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Lingual and Gastric Lipases: Their Role in Fat Digestion (Routledge Revivals)
by Margit HamoshFirst published in 1990: This book discusses the role of fat digestion with regards to Lingual and Gastric Lipases.
Linguistic Theory for Aphasia
by Maria Garraffa Giuditta SmithThis book presents a cutting-edge overview of the language models of in phonology, morphology, syntax, and pragmatics, proposed to underlie language phenotypes across aphasic syndromes, as well as the potential applications of linguistic theory to advance therapeutic treatment -and research- in aphasiology. It draws together examples from a range of aphasic syndromes, providing valuable insights into the way language-specific properties may affect the manifestation of language deficits across aphasia. The authors discuss experimental evidence of deficits across language domains, which is crucial to those who study language abilities in aphasia. It concludes by examining how linguistic theory might contribute to patient classification in aphasia and to future directions for research in experimental linguistics and aphasiology. This book will appeal to students and scholars of neuropsychology, psycholinguistics, linguistics, and speech and language therapy.
Linkage Disequilibrium and Association Mapping
by Andrew R. CollinsAs researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. They provide cutting-edge analysis of the most up-to-date and preeminent information available.
Linking Health and Education for African American Students' Success
by Nadine M. Finigan-CarrThe linkages between a student’s health and a student’s ability to learn have been well established. Children who are sick stay home; and, children at home cannot learn if they are not in school leading to increased dropout rates among other educational outcomes. However, an understanding of this concept is just the beginning of understanding how education and public health are inextricably linked. In light of this, Linking Health and Education for African American Students’ Success examines health disparities and education inequities simultaneously and moves beyond a basic understanding of health and education in K-12 school programs. The structural inequalities which lead to reduced academic attainment mirror the social determinants of health. Education is one of the most powerful determinants of health, and disparities in educational achievement as a result of structural inequalities closely track disparities in health. These disparities lead to both sub-standard healthcare and reduced academic attainment among children from underserved minorities in the United States, especially African Americans. This book discusses how this may result in children with poorer mental health outcomes; higher school dropout rates; increased risks of arrests and incarceration; higher rates of chronic diseases and mortality; and overall diminished opportunities for success, while providing suggestions as to how to address these issues. This results in an insightful read for researchers, academics and practitioners in the fields of healthcare and education.
Linking Housing and Services for Older Adults: Obstacles, Options, and Opportunities
by Jon Pynoos Penny Hollander Feldman Joann AhrensPackaging supportive services with housing-a pressing issue for older adultsThe population of older adults is expected to explode in the coming years. Linking Housing and Services for Older Adults: Obstacles, Options, and Opportunities examines a crucial, complex, and often overlooked issue for policymakers and the public at large: older adults&’ increasing needs for housing and supportive long-term care services. As baby boomers strive to help their parents make difficult decisions about their options, pressure mounts for policymakers to develop appropriate housing and services. This book brings together respected experts to discuss the answers to difficult questions about meeting the housing and support service needs of aging adults.Linking Housing and Services for Older Adults: Obstacles, Options, and Opportunities explores in-depth the tough issues pertaining to which populations are presently being served, what their needs are, and who is being left out. You&’ll learn exactly what types of services are available, who is providing them, and how are they packaged. From residential care to assisted living to institutional care, this book addresses all facets of the complicated problems of providing availability to fulfill need. This important source presents insightful analysis of the total range of issues and the challenges to progress as well as offering specific recommendations to effectively offer housing and vital long-term care supportive services to older adults.Linking Housing and Services for Older Adults: Obstacles, Options, and Opportunities discusses in detail: the argument for increased development of supportive housing for older adults-and the barriers preventing it the issues related to providing a variety of housing and service options to the Medicaid population two case studies that illustrate how policies aimed at linking housing and services play out at the state and local level-and the need for strong leadership and the ability to develop key partnerships as vital aspects for success the interrelationship of factors regarding nursing home admission, the availability of subsidized housing, and Medicaid eligibility the need for care management to be holistic-including environmental care assessment, repair, and renovation management in addition to current long-term care settings creating affordable assisted living facilities for older persons receiving Medicaid services the successful components of the national Coming Home Program four case studies emphasizing different finance and regulatory approaches-providing lessons learned for developers, state agencies, and advocates of affordable assisted livingThis vital educational resource is also an essential reference for local, state, and national policymakers, housing officials, and long-term care providers.
Linking Research and Public Health Practice: A Review of CDC's Program of Centers for Research and Demonstration of Health Promotion and Disease Prevention
by National Research CouncilHealth promotion and disease prevention are central priorities in the Centers for Disease Control and Prevention (CDC) vision. To advance research in these areas, Congress authorized and CDC established a program of university-based Centers for Research and Demonstration of Health Promotion and Disease Prevention to explore improved ways of appraising health hazards and to serve as demonstration sites for new and innovative research in public health. Begun in 1986 with three centers, there are now fourteen. In response to a CDC request to evaluate the program, Linking Research and Public Health Practice examines the vision for the prevention research centers program, the projects conducted by the centers, and the management and oversight of the program. In conducting the evaluation, the IOM committee took a broad view of how prevention research can influence the health of communities, and considered both the proximal risk factors for disease prevention and the more distal conditions for health promotion and improved equity in the distribution of risk factors. Month?
Linkshändigkeit und Hirnasymmetrien: Eine Einführung (essentials)
by Sebastian OcklenburgDieses essential gibt einen Überblick über aktuelle Forschung zum Thema Linkshändigkeit und Hirnasymmetrien. Dabei werden neben Grundlagen zur Erfassung von Linkshändigkeit und Hirnasymmetrien auch ihre Evolution, Entwicklung und ihre Erforschung im Tierreich beleuchtet. Weitere Themenschwerpunkte sind die Erforschung zwischen Linkshändigkeit und kognitiven Funktionen sowie das Thema Händigkeit und Sport. Abgerundet wird das essential durch eine Besprechung des Themas Umlernen der Händigkeit und eine Diskussion veränderter Asymmetrien bei verschiedenen Patientengruppen.
Lip Cancer
by Antonia KolokythasThis textbook is intended as a comprehensive reference that will provide easy-to-follow and well-organized guidance on the management of lip cancer, from diagnosis to treatment and reconstruction. After discussion of anatomy and premalignant conditions, detailed attention is paid to squamous cell carcinoma of the lip. Surgical management is explained, and the roles of radiation therapy and chemotherapy, discussed. Reconstruction techniques following ablative surgery are then described in depth, with reference to defect size and complexity. In addition, the potential complications of treatment and reconstruction are presented, with advice on their management. The closing chapter considers other malignant lesions of the lip. The informative text is complemented by high-quality illustrations and clinical and radiographic material. The contributors all have extensive experience and in-depth knowledge of the topics they address.
Lip Reading
by Harry KrausShe Could Save Millions, or Save Herself She just needs a little longer. She's really close. Dr. Rebecca Jackson, a medical researcher, stands on the verge of a breakthrough that will transform medicine. But she soon discovers the reason behind the miraculous progress in her research, and it leaves her with a nearly impossible choice . . . and little time to decide. More than her research is at stake. And more threatens it than this latest revelation. Something she's tried hard to cover up. There is a high cost to some things in medicine and it's not always the patient who pays. Can Rebecca find the faith and wisdom she needs to make the right call? The clock is ticking and the pressure is on.
Lipedema: A Practical Guidebook
by Zaher Jandali Lucian P. Jiga Corrado CampisiThis book is written as a guide for patients suffering from lipedema. Known as a common, painful fat distribution disorder characterised by a disproportional fat accumulation, lipedema represents an unmet medical need where scientific evidence on both pathophysiology and its treatment is still lacking. As the number of affected patients is increasing, besides striving to map the conundrum of clinical signs and relate these to their underlying mechanisms, developing standardised approaches addressing both fat mass reduction and body contouring are key issues able to warrant therapeutic success. In this book, our intention was to look at this complex disease from all its actual perspectives and provide a concise summary of the actual state of knowledge for all those affected. After looking into the most actual data on the aetiology, pathophysiology and course of the disease, the book then focuses on our complex treatment protocols wherecurrent conservative and surgical treatment options are systematically analyzed, considering their long-term chances of success as well as associated risks and side effects. We propose a three step treatment approach. 1st step initiates with weight control and addresses obesity, if present. 2nd step is an individual liposuction therapy plan to treat all lipedema areas, and more. 3rd step includes body contouring surgery, only in patients with massive skin laxity after liposuction and / or massive weight loss.
Lipid Management
by Hussein YassineThe purpose of this work is to provide an update on our understanding of lipids in the clinic using information from recent clinical trials and in special populations. This will be a concise, easy to read book. We will cover LDL, HDL and triglyceride metabolism in the first chapters. We will provide updates from recent HDL trials where raising HDL cholesterol did not translate into reduced cardiovascular events and revisit the role of HDL cholesterol in heart disease (Dr. Yassine). The vast majority of authors are confirmed. Dr. Goran will review lipids abnormalities in children with a particular focus on vulnerable populations (emphasis on ethnicity and childhood obesity). Dr. Goldberg will review the treatment goals for managing lipids in clinic. Dr. Abela will provide his expertise on the link between inflammation and lipids, and how this relates to atherosclerosis development. I invited Drs. Howard Hodis and Wendy Mack (world renowned experts on carotid imaging) to provide an update on measures of subclinical atherosclerosis in patients with abnormal lipid levels. Finally, I invited Dr. Michael Dube to provide an update on how new HIV medications impact lipid levels. Overall, this somewhat small book will be an excellent resource for understanding changes in lipids in different populations with an updated approach to managing complicated lipid cases.
Lipid Mediators and Their Metabolism in the Brain
by Akhlaq A. FarooquiLipid Mediators and Their Metabolism in the Brain presents readers with cutting edge and comprehensive information not only on the synthesis and degradation of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, but also their involvement in neurological disorders. It is hoped that this monograph will be useful not only to postgraduate student and their teachers, but also to research scientists and physicians, who are curious about the generation and roles of lipid mediators in the brain.
Lipid Mediators in Allergic Diseases of the Respiratory Tract
by Clive RobinsonPostgraduates and researchers in the study of allergies, clinical immunology, chest diseases, pharmacology, physiology and biochemistry.
Lipid Metabolism and Health
by Bryant Stamford Robert J. MoffattThat a relation exists between lipids/lipoproteins and coronary artery disease is no longer an arguable point. However, the complexities associated with this relationship, and the number of factors that can impact and alter circumstances and clinical status, are many and diverse. Consequently, this relationship continues to receive a great deal of
Lipid Metabolism in Tumor Immunity (Advances in Experimental Medicine and Biology #1316)
by Yongsheng LiThis book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery.
Lipid Oxidation in Health and Disease (Oxidative Stress and Disease)
by Corinne M. Spickett Henry Jay FormanOxidative modification of lipids and phospholipids-including radical damage, halogenation, and nitration-result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of
Lipid Peroxidation In Biomembranes
by Valerian E. KaganThis book will explain the colossal potential of life to cope with different living environments is possible owing to the exceptionally well developed mechanisms of adaptation to environmental conditions. There is an innumerable variety of concrete mechanisms which make it possible for living creatures to adapt to different and changing environmental conditions. Nevertheless, all this variety is the manifestation of the three strategic line of the adaptation process: 1. Evolutional or genotypic adaptation. 2. Phenotypic adaptation. 3. Rapid adaptation.
Lipid Signaling in Human Diseases (Handbook of Experimental Pharmacology #259)
by Julian Gomez-Cambronero Michael A. FrohmanLipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their reaction products have been implicated in fundamental cellular processes including cell proliferation, division and migration. These enzymes and their products underlie the molecular mechanisms of numerous human diseases, in particular metabolic disease (diabetes), cancer, neurodegenerative disease and cardiovascular disease.Over the last decade, studies have advanced to the point that a number of inhibitors for these enzymes have been developed to attempt to ameliorate these conditions; some of the inhibitors are currently in human clinical trial. The need for this book is to review the current status of this field and the prospect for the inhibitors to be clinically important.
Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease (Advances in Experimental Medicine and Biology #1276)
by Xian-Cheng JiangThis book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.
Lipid-Mediated Signaling (Methods in Signal Transduction Series)
by Eric J. Murphy Thad A. RosenbergerAs the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand
Lipid-mediated Protein Signaling
by Daniel G.S. CapellutoThis book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.
Lipidomics
by Sanjoy K. BhattacharyaThis volume explores lipidomics through protocols that focus on areas of utility, techniques, and bioinformatics advancements. The protocols in this book cover topics such as isolation of specific membranes and specialized fractionation of subcellular compartments, and computational and functional analysis of lipid metabolizing enzymes. Each protocol also discusses methods of dealing with fractionated organelles--cells to whole organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Lipidomics: Methods and Protocols is a useful and valuable resource for biochemists, molecular biologists, and neuroscientists interested in neurology, ophthalmology and vision sciences, as well as mass spectrometrists with interest in disease discovery.
Lipidomics in Health & Disease: Methods & Application (Translational Bioinformatics #14)
by Xiangdong Wang Duojiao Wu Huali ShenThis volume covers the emerging area of science, Clinical Lipidomics, which is the application of lipidology to the understanding of physiological and pathophysiological changes of lipidomes, with a special focus on lipidomic profiles in human diseases.Lipidomics is widely used to map lipid molecular species in a biological system. Clinical lipidomic analysis has demonstrated the comprehensive characterization of molecular lipids in various severities, durations, and therapies as a critical tool in identification and validation of disease-specific biomarkers. This volume on Clinical Lipidomics will add to the literature and help advance the knowledge of the pathogenesis, diagnosis, prevention and treatment of diseases.
Lipidomics of Stem Cells
by Alice Pébay Raymond C.B. WongThis book combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells. Examples of different classes of lipids--such as sphingolipids, lysophospholipids, cannabinoids and neutral lipids--are described and illustrate the vast biological effects of this class of molecules. The international contributors are all recognized experts in their respective fields. Covering the various aspects of the topic, Lipidomics of Stem Cells provides an up-to-date snapshot--unique among the literature--of where the lipid world is in term of understanding the roles of lipids in stem cell biology. It provides an essential reference for stem cell biologists, lipid biologists, development biologists, students, academics and clinicians in related areas.
Lipids and Atherosclerosis
by Chris J. Packard Daniel J. RaderNew discoveries in genetics, molecular, and cell biology are not only enhancing our understanding of the etiology and progression of disease, but are finding applications in the development of new drugs or the implementation of new kinds of therapy. This book provides an in-depth review of emerging areas in biomedical research at the interface of s