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Lying in the Dark Room: Architectures of British Maternity (Routledge Research in Architecture)

by Emma Cheatle

Lying in the Dark Room: Architectures of British Maternity returns to and reflects on the spatial and architectural experience of childbirth, through both a critical history of maternity spaces and a creative exploration of those we use today. Where conventional architectural histories objectify buildings (in parallel with the objectification of the maternal body), the book—in the mode of creative practice research—presents a creative-critical autotheory of the architecture of lying-in. It uses feminist, subjective modes of thinking that travel across disciplines, registers and arguments. The book assesses the transformation of maternity spaces—from the female bedchamber of seventeenth- and eighteenth-century marital homes, to the lying-in hospitals of the eighteenth and nineteenth centuries purposely built by man-midwives, to the late twentieth-century spaces of home and the modern hospital maternity wing—and the parallel shifts in maternal practices. The spaces are not treated as mute or neutral backdrops to maternal history but as a series of vital, entangled atmospheres, materials, practices and objects that are produced by, and, in turn, produce particular social and political conditions, gendered structures and experiences. Moving across spaces, systems, protagonists and their subjectivities, the book shows how hospital design and protocol altered ordinary birth at home and continues to shape maternal spatial experience today. As such, it will be of interest to a wide range of readers, from architectural historians, theoreticians, designers and students to medical humanities historians, to English Literature, humanities and material studies scholars, as well as those interested in creative-critical writing.

Lyle Creelman

by Susan E. Armstrong-Reid

This intriguing scholarly biography examines the important contributions of Canada's foremost international nurse, Lyle Creelman. Creelman parlayed her experience as a community health nurse in British Columbia into significant international appointments with two organizations undertaking massive responsibility for health tasks in the post-war period - first, as chief nurse of the British Zone of Occupied Germany with the United Nations Relief and Rehabilitation Administration (UNRRA), and, from 1954 to 1968, the Chief Nursing Officer of the World Health Organization (WHO).In telling Creelman's fascinating story, Susan Armstrong-Reid helps readers learn about the transformation of the nursing profession and global health governance in the twentieth century. This story challenges the prevailing portrait of expatriate nurses during this period as agents of Western cultural imperialism. Lyle Creelman: The Frontiers of Global Nursing not only recasts the broader historical narrative of nursing's legacy to global health, but contextualizes its continuing importance for approaching health care in the twenty-first-century.

Lyme Borreliosis

by Jeremy Gray Klaus-Peter Hunfeld

This book is a compact clinical introduction to Lyme borreliosis for physicians of all specialties who care for patients with suspected B. burgdorferi infection, whether in hospital or general practice. The book provides a great deal of practice-oriented information on symptomatology, diagnosis, treatment, and prophylaxis with a special emphasis on the situation in Europe. At the same time, it describes contemporary scientific knowledge in as much detail as is required in order to understand the pathogenetic relationships and their relevance to medical care. The authors are members of an interdisciplinary expert group of epidemiologists, biologists, microbiologists, and clinicians who have been working in the area of tick-borne diseases for many years. The personal experience of each of the authors, accumulated through their daily work with patients in special clinics or by confrontation with complicated questions in basic research, epidemiology, and laboratory diagnostics of Lyme borreliosis, represents an important mainstay of the book. Written from the perspective of clinical management and practical problem-solving, this topical monograph will assist clinicians in meeting diagnostic challenges and providing appropriate medical aid to patients with Lyme borreliosis.

Lyme Carditis: From A to Z

by Adrian Baranchuk Rachel Wamboldt Chang Nancy Wang

This book provides valuable tools for the appropriate diagnosis and management of Lyme carditis. It includes epidemiological, pathophysiological and clinical recommendations for the identification, confirmation and management of the disease. With one score that currently facilitates diagnosing Lyme carditis when patients present with undiagnosed complete heart block (the “SILC Score”), a rapid recognition of Lyme carditis as the cause of conduction disorders is essential to allow early treatment with IV antibiotics with a high probability of complete resolution and avoiding unnecessary pacemaker implantation. Lyme carditis: From A to Z provides a clinical algorithm to facilitate management, pre-discharge evaluations of the conduction system and long-term follow-up of patients properly treated for Lyme carditis. It provides a proven approach to patients implanted with cardiac devices and in whom Lyme carditis is subsequently diagnosed, while it also explores the possibility of Lyme dilated cardiomyopathy as a chronic manifestation of Lyme disease. This book therefore represents an original and unique resource that sheds light on an important topic of discussion in many endemic regions of the world.

Lyme Disease: An Evidence-based Approach

by Robert Smith Paul G Auwaerter Phillip J. Baker Alan G Barbour Dag Berildda Raymond J Dattwyler Rick Dersch David M Dudzinski Randi Eikeland Afton L. Hassett Linden Hu Adriana Marques Paul S Mead Robert B Nadelman Erlend Roaldsnes Jonathan R Salik Eugene D Shapiro Lenard Sigal Kirk Sperber Gerold Stanek Franc Strle Klemen Strle Gary Wormser

This new edition of Lyme Disease provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. This book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives on all aspects of Lyme disease and explicitly review both the basic biology of the infection and practical clinical aspects. This new edition: Includes new borrelial pathogens that have been identified (B. miyamotoi, B. mayonii and B. bavariensis among others). Provides updated information on the molecular biology of the organism, neuroborreliosis, and the role of the C6 peptide in diagnosis. Discusses the controversies about 'chronic Lyme disease', post Lyme disease syndrome and other ongoing but non-specific symptoms that have been attributed to this infection. As the endemic footprint of Lyme disease continues to grow, this book provides a broad and detailed guide for clinicians and researchers involved with the diagnosis and treatment of the condition. Covering biology, epidemiology and therapeutics, it is also essential reading for students of global health and infectious disease.

Lyme Disease: An Evidence-based Approach

by John J. Halperin

This new edition of Lyme Disease provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. This book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives on all aspects of Lyme disease and explicitly review both the basic biology of the infection and practical clinical aspects.

Lyme Disease: Why It’s Spreading, How It Makes You Sick, and What to Do about It (A Johns Hopkins Press Health Book)

by Alan G. Barbour

A world-renowned Lyme disease expert explains everything you need to know if you live, work, or play in areas with the ticks that carry disease.Once restricted to small forested areas in the northeast and north-central United States, Lyme disease is now a common infection in North America and Europe. The Centers for Disease Control and Prevention estimate that more than 300,000 new cases occur each year in the United States. Misunderstandings over symptoms and treatment increase the public's concerns about the disease—which, if not properly treated, can become chronic and debilitating. An expert on tick-borne diseases, Alan G. Barbour explains the course of illness that results from infection, diagnosis and treatment options, and steps that can be taken to avoid a tick bite in the first place. The ticks that transmit Lyme disease may also transmit other disease-causing pathogens, and these other infections are considered as well. Drawing on real case histories of individuals with Lyme disease—or illnesses that may be mistaken for Lyme disease—Barbour explains: The biology of the spirochete, Borrelia burgdorferi, that causes Lyme disease The role of animals such as mice that carry the infection The life cycle of the ticks that transmit the infection The importance of deer in perpetuating the cycle The basics of diagnostic laboratory tests and how test results are interpreted How antibiotics are used in treating Lyme diseaseInfected ticks are abundant in the woods, in walking trails, and in the shrubs and tall grass where suburban lawns meet wooded areas. Barbour stresses preventing disease through community-wide ecology projects and individual and household protection. While it may be difficult to escape infection, understanding the danger, the symptoms, and the treatment goes a long way toward preventing long-term health consequences. Featuring a list of reliable web sites and a glossary of terms, Lyme Disease is an invaluable resource for everyone who is at risk of the disease or is involved in preventing and treating it.

Lyme disease: Global Status 2010 edition

by Dr Stephen Berger Gideon Informatics

Lyme disease: Global Status is one in a series of GIDEON ebooks which summarize the status of individual infectious diseases, in every country of the world. Data are based on the GIDEON database (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing search of the medical literature. Chapters are arranged alphabetically, by country name. Each section is divided into five subsections. 1. Descriptive epidemiology 2. Summary of clinical features 3. Global status of the disease 4. Status of the disease in a specific country 5. References

Lyme-Borreliose

by Jeremy Gray Klaus-Peter Hunfeld

Dieses Buch ist eine kompakte klinische Einführung in die Lyme-Borreliose für Ärzte aller Fachrichtungen, die Patienten mit Verdacht auf B. burgdorferi-Infektion betreuen, sei es im Krankenhaus oder in der Allgemeinpraxis. Das Buch bietet viele praxisorientierte Informationen zu Symptomatik, Diagnose, Behandlung und Prophylaxe mit besonderem Schwerpunkt auf der Situation in Europa. Gleichzeitig beschreibt es den aktuellen wissenschaftlichen Kenntnisstand so detailliert, wie es für das Verständnis der pathogenetischen Zusammenhänge und deren Relevanz für die medizinische Versorgung erforderlich ist. Die Autoren sind Mitglieder einer interdisziplinären Expertengruppe von Epidemiologen, Biologen, Mikrobiologen und Klinikern, die seit vielen Jahren auf dem Gebiet der zeckenübertragenen Krankheiten tätig sind. Die persönliche Erfahrung jedes einzelnen Autors, die er durch die tägliche Arbeit mit Patienten in Spezialkliniken oder durch die Konfrontation mit komplizierten Fragen der Grundlagenforschung, Epidemiologie und Labordiagnostik der Lyme-Borreliose gesammelt hat, stellt eine wichtige Stütze des Buches dar. Aus dem Blickwinkel des klinischen Managements und der praktischen Problemlösung geschrieben, wird diese aktuelle Monographie den Kliniker bei der Bewältigung diagnostischer Herausforderungen und der angemessenen medizinischen Versorgung von Patienten mit Lyme-Borreliose unterstützen.

Lyme: The First Epidemic of Climate Change

by Mary Beth Pfeiffer

Lyme disease is spreading rapidly around the globe as ticks move into places they could not survive before. The first epidemic to emerge in the era of climate change, the disease infects half a million people in the US and Europe each year, and untold multitudes in Canada, China, Russia, and Australia.Mary Beth Pfeiffer shows how we have contributed to this growing menace, and how modern medicine has underestimated its danger. She tells the heart-rending stories of families destroyed by a single tick bite, of children disabled, and of one woman's tragic choice after an exhaustive search for a cure.Pfeiffer also warns of the emergence of other tick-borne illnesses that make Lyme more difficult to treat and pose their own grave risks. Lyme is an impeccably researched account of an enigmatic disease, making a powerful case for action to fight ticks, heal patients, and recognize humanity's role in a modern scourge.

Lymph Node Cytopathology

by Stefan E. Pambuccian Ricardo H. Bardales

This volume in the Essentials in Cytopathology book series will focus on the cytopathology of lymph nodes. It will address the topic of fine needle aspiration of lymph nodes and fulfill the need for an easy-to-use and authoritative synopsis of lymph node cytopathology. The book with adopt an algorithmic diagnostic approach, starting from the cytomorphologic pattern of the lymph node aspirate. The focus will be on the appropriate and effective use of ancillary studies (immunohistochemistry, flow cytometry, fluorescence in situ hybridization and molecular techniques) and integration of their results into the final diagnosis. The book will present the cytopathologic features and differential diagnoses for the major cytologic patterns in lymph node fine needle aspiration. The entities typically falling within each of these patterns will be discussed with illustration of the spectrum of cytologic features, differential diagnoses and pitfalls. The book will cover the full spectrum of benign and malignant primary conditions of the lymph nodes, with emphasis on common disorders. Discussion of metastatic conditions will be restricted to those that are relevant to the differential diagnosis of primary lymphoid disorders. This book is designed as an easy to use resource that fits into the lab coat pocket, ideal for portability and quick reference. It is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in lymph node aspirates. The accompanying text follows an easy to use pattern-based outline. A useful resource for every pathologist, cytopathologist, fellow and trainee.

Lymph Stasis: Pathophysiology, Diagnosis, and Treatment (Routledge Revivals)

by Waldemar L. Olszewski

First published 1991. Lymph Stasis: Pathophysiology, Diagnosis, and Treatment provides a reintroduction to the lymphatic system and its primary disease-lymph stasis-to practitioners who treat patients with lymph stasis of the limbs. Topics discussed include an introduction to the lymphatic system in man, the structure of lymphatics and the mechanism of lymph formation based on animal and human studies, chemical and cellular composition of lymph in humans, pathological factors affecting lymph flow, treatment of lymphedema, and clinical studies on antibiotic penetration to tissue fluid and lymph. Angiologists, vascular surgeons, dermatologists, radiologists, and nuclear medicine specialists are among those physicians who will find a wealth of useful information in this book.

Lymphatic Filariasis

by Trilok Chandra Goel Apul Goel

This book provides up-to-date information on lymphatic filariasis supported with abundant images, tables and algorithms. It is a first such monograph on a disease that has varied presentations which are complete clinical entities, such as chyluria, hydrocele, elephantiasis, etc. This book consists of three parts, parasitology, acute clinical manifestations and chronic presentations of the disease. Approximately 120 million people are infected with lymphatic filariasis in tropical and subtropical countries. About a third of these suffer clinical consequences of this infection, and many are seriously disfigured. India, Indonesia and Nigeria are the most endemic countries in the world. In spite of Global Control Program of WHO, filariasis continues to be a significant medical challenge and current efforts underway will take a long time to bring it under control. Lymphatic Filariasis is meant for general surgeons, physicians, urologists and plastic surgeons, including the postgraduate students. Useful for epidemiologists, internists, and those involved in filariasis prevention programs.

Lymphatic Filariasis: Epidemiology, Treatment And Prevention - The Indian Perspective

by Brij Kishore Tyagi

Lymphatic Filariasis (LF) is a group of human and animal infectious diseases caused by nematode parasites of the order Filariidae. Often neglected, it is one of the oldest and the most debilitating tropical diseases (NTDs), transmitted from human to human by mosquitoes bites, particularly the brown black mosquito known as Culex quinquifasciatus. LF is a major public health problem in many parts of the tropics, especially India, which accounts for as much as 40% of total global cases. As a leading cause of permanent and long-term disability worldwide, the parasite infection imposes a severe physical and socioeconomic burden. The World Health Organization (WHO) estimates that 1.4 billion people live in high-risk areas – 120 million of which are already infected with LF, including 22 million children below the age of 15 and about 76 million who suffer from damaged lymphatic and renal systems.India has made great strides toward eliminating the disease, and these advances are of global significance. They include early diagnosis mechanisms, vaccine product development, detection of parasites in the vector, and studies on parasite evolution trends in nature as warning signals. Reports on the successes and failures are needed to enable measures to be taken to avoid disaster and ensure a smooth transition from endemicity in India to the elimination of lymphatic filariasis by 2020. This book, which gathers highly original contributions on various subjects related to lymphatic filariasis, discusses the latest scientific research that will help the nation to achieve this milestone. It also serves as a guide to many other countries struggling against this highly debilitating and incapacitating disease.

Lymphatic Transport of Drugs

by William N. Charman

Lymphatic Transport of Drugs provides a thorough review of the determinants that affect the uptake and delivery of drugs and xenobiotics to the lymphatics. Factors affecting the transport and delivery of lipophilic drugs through the lymph after oral administration, lymphatic transport of polar drugs and macromolecules after gastrointestinal dosing, transport of drugs into the lymph after parenteral administration, and particulate drug delivery systems are among the topics examined in this volume. Lymphatic Transport of Drugs is primarily intended for pharmaceutical scientists who are attempting to alter the delivery of current therapeutic agents through formulation of prodrugs, as well as for researchers designing new drugs for lymph delivery.

Lymphedema

by Arin K. Greene Sumner A. Slavin Håkan Brorson

This volume is a clinically-oriented book that can be used for patient care, teaching, or research. It covers the entire field of lymphedema, including both primary and secondary disease, as well as all diagnostic and treatment modalities. The text begins with a foundation for the condition, including its pathophysiology, epidemiology, and morbidity. Next, the classification of lymphedema is covered which is the template for accurate diagnosis. Clinical, radiological, and differential diagnosis of lymphedema is also reviewed. Finally, conservative and operative management is presented, including both physiologic and excisional procedures. Lymphedema: Presentation, Diagnosis, and Treatment provides a comprehensive, easy-to-read reference for any health care provider managing a patient with lymphedema. The text is clinically-focused, evidence-based, and practical. The reader, regardless of his/her level of training or specialty, will be able to adequately treat a patient with lymphedema using this resource. To facilitate its use in clinical settings, the book was designed to be portable. In addition, diagnostic and treatment algorithms are included to further simplify the management of these patients. Patient images are presented throughout the text to illustrate the clinical care of lymphedema. All chapters are written by experts in the field, and contain the most current information on the topic.

Lymphedema

by Byung-Boong Lee John Bergan Stanley G. Rockson

Lymphedema: A Concise Compendium of Theory and Practice brings into one volume the most important sources of information to guide the evaluation and treatment of patients with lymphedema. The management of chronic lymphedema continues to challenge both patients and treating physicians worldwide. In the past decades, however, substantial progress has been achieved for both diagnosis and therapy of these disabling conditions. With increasing attention to the quality of life, this debilitating life-long disease is receiving more attention not only by lymphedema specialists, but also by clinicians across the spectrum of health care delivery. Lymphedema: A Concise Compendium of Theory and Practice provides clear, concise background and recommendations in an easy-to-use format. It is a valuable reference tool for clinical practitioners (physicians/nurse practioners/technicians) who wish to deliver state-of-the-art health care to their patients with lymphatic and venous disorders.

Lymphedema

by Byung-Boong Lee John Bergan Stanley G. Rockson

A comprehensive, evidence-based introduction to the area of lymphology, the book is directed mainly to the US audience and will appeal to an interdisciplinary field of health professionals. It describes the unique anatomy and physiology of the lymphatic system and the intimate relationship it shares with the venous system. It explores the differential diagnosis of the "swollen leg/arm", which is often the presenting problem to the health care professional. The necessity of history taking, physical examination and laboratory studies are noted. Treatment methods are described as an introduction and psychosocial and quality of life issues are explored in depth.

Lymphocyte Homing to the Skin: Immunology, Immunopathology, and Therapeutic Perspectives

by Wolf-Henning Boehncke

Over the last decade, enormous progress in the understanding of T-cell homing has made it possible to identify the multitude of molecules involved, such as cytokines, chemokines, and adhesion molecules, and to unravel their complex interactions resulting in controlled, non-random T-cell recirculation. These insights are now being explored therapeut

Lymphocyte Immunization Therapy (LIT) in Reproductive Failures: New Horizons

by Mohan Raut Mugdha Raut

Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis.This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective.The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained.The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy.The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers.The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.

Lymphoma

by Anas Younes Bertrand Coiffier

Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.

Lymphoma

by Robert Marcus Robert Marcus John W. Sweetenham Michael E. Williams John W. Sweetenham

Major advances have occurred in the diagnosis and treatment of lymphoma in recent years. Our understanding of the molecular biology and genetics of the disease has increased exponentially, and significant imaging developments have resulted in earlier and more accurate diagnosis. The new edition of this landmark text places these advances in the context of daily clinical practice. Each chapter has been updated to reflect recent developments, including new treatment agents such as immunomodulatory drugs and the next generation of antibodies, and the increasing prognostic role of PET scanning. Results from recent large-scale clinical trials are presented, and pathology and cytogenetics are integrated into discussion of each disease entity, enabling the reader to review all the key diagnostic information in one place. Featuring many color illustrations, and written and edited by leading authorities in the field, Lymphoma provides all the information you need to diagnose and manage these complex disorders.

Lymphoma

by Peter W. Johnson Tim Illidge

A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for providing for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question.

Lymphoma

by Ralf Küppers

Lymphomas are lymphoid malignancies derived from B or T lymphocytes, and their study has been and still is paradigmatic for many aspects of cancer research. Lymphoma: Methods and Protocols presents and discusses key methods that are used in lymphoma research, partly specific for lymphoma research but often adaptable to the study of other cancers. By covering a broad variety of methods used in lymphoma research, this book will be of interest not only for hematologists, hematopathologists, and immunologists but also for scientists interested in other fields of cancer research as well as human genetics. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Versatile and cutting-edge, Lymphoma: Methods and Protocols serves researchers studying human physiology with the ultimate goal of understanding and controlling these often terrible diseases.

Lymphoma and Leukemia of the Nervous System

by Lisa M. Deangelis Tracy Batchelor

This is the second edition of a book called "Lymphoma of the Nervous System," which was published by Butterworth-Heinemann (B-H) in 2004. Lymphoma and Leukemia of the Nervous System is a comprehensive review of this challenging group of diseases and should be useful for the practicing neurologist, hematologist, oncologist and for any practitioner involved in the management of these patients.

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