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Machine Learning for Critical Internet of Medical Things: Applications and Use Cases
by Fadi Al-Turjman Anand NayyarThis book discusses the applications, challenges, and future trends of machine learning in medical domain, including both basic and advanced topics. The book presents how machine learning is helpful in smooth conduction of administrative processes in hospitals, in treating infectious diseases, and in personalized medical treatments. The authors show how machine learning can also help make fast and more accurate disease diagnoses, easily identify patients, help in new types of therapies or treatments, model small-molecule drugs in pharmaceutical sector, and help with innovations via integrated technologies such as artificial intelligence as well as deep learning. The authors show how machine learning also improves the physician’s and doctor’s medical capabilities to better diagnosis their patients. This book illustrates advanced, innovative techniques, frameworks, concepts, and methodologies of machine learning that will enhance the efficiency and effectiveness of the healthcare system.Provides researchers in machine and deep learning with a conceptual understanding of various methodologies of implementing the technologies in medical areas;Discusses the role machine learning and IoT play into locating different virus and diseases across the globe, such as COVID-19, Ebola, and cervical cancer;Includes fundamentals and advances in machine learning in the medical field, supported by significant case studies and practical applications.
Machine Learning for Disease Detection, Prediction, and Diagnosis: Challenges and Opportunities
by Tanupriya Choudhury Avita KatalThe book &“Machine Learning for Disease Detection, Prediction, and Diagnosis&” can be a comprehensive guide to the novel concepts, techniques, and frameworks essential for improving the viability of existing machine-learning practices. It provides an in-depth analysis of how these new technologies are helpful to detect, predict and diagnose diseases more accurately. The book covers various topics such as image classification algorithms, supervised learning methods like support vector machines (SVM), deep neural networks (DNNs), convolutional neural networks (CNNs), etc. unsupervised approaches such as clustering algorithms as well as reinforcement learning strategies. This book is an invaluable resource for anyone interested in machine-learning applications related to disease detection or diagnosis. It explains different concepts and provides practical examples of how they can it implements using real-world data sets from medical imaging datasets or public health records databases, among others. Furthermore, it offers insights into recent advances made by researchers which have enabled automated decision-making systems based on AI models with improved accuracy over traditional methods. This text also discusses ways through which current models could improve further by incorporating domain knowledge during the model training phase, thereby increasing their efficacy even further. Overall, this book serves as a great source of information about the latest advancements made in the field of Machine Learning & Artificial Intelligence towards efficient building systems capable enough detecting & diagnosing diseases automatically while avoiding human errors resulting due manual intervention at any stage along process pipeline thus ensuring better outcomes overall. Moreover, it helps readers understand the underlying principles behind each technique discussed so that they may apply them according to their own application scenarios efficiently without worrying much about the implementation details required to get the job done the right way the first time around itself!
Machine Learning for Health Informatics
by Andreas HolzingerMachine learning (ML) is the fastest growing field in computer science, and Health Informatics (HI) is amongst the greatest application challenges, providing future benefits in improved medical diagnoses, disease analyses, and pharmaceutical development. However, successful ML for HI needs a concerted effort, fostering integrative research between experts ranging from diverse disciplines from data science to visualization. Tackling complex challenges needs both disciplinary excellence and cross-disciplinary networking without any boundaries. Following the HCI-KDD approach, in combining the best of two worlds, it is aimed to support human intelligence with machine intelligence. This state-of-the-art survey is an output of the international HCI-KDD expert network and features 22 carefully selected and peer-reviewed chapters on hot topics in machine learning for health informatics; they discuss open problems and future challenges in order to stimulate further research and international progress in this field.
Machine Learning for Healthcare: Handling and Managing Data
by Rashmi Agrawal, Jyotir Moy Chatterjee, Abhishek Kumar, Pramod Singh Rathore and Dac-Nhuong LeMachine Learning for Healthcare: Handling and Managing Data provides in-depth information about handling and managing healthcare data through machine learning methods. This book expresses the long-standing challenges in healthcare informatics and provides rational explanations of how to deal with them. Machine Learning for Healthcare: Handling and Managing Data provides techniques on how to apply machine learning within your organization and evaluate the efficacy, suitability, and efficiency of machine learning applications. These are illustrated in a case study which examines how chronic disease is being redefined through patient-led data learning and the Internet of Things. This text offers a guided tour of machine learning algorithms, architecture design, and applications of learning in healthcare. Readers will discover the ethical implications of machine learning in healthcare and the future of machine learning in population and patient health optimization. This book can also help assist in the creation of a machine learning model, performance evaluation, and the operationalization of its outcomes within organizations. It may appeal to computer science/information technology professionals and researchers working in the area of machine learning, and is especially applicable to the healthcare sector. The features of this book include: A unique and complete focus on applications of machine learning in the healthcare sector. An examination of how data analysis can be done using healthcare data and bioinformatics. An investigation of how healthcare companies can leverage the tapestry of big data to discover new business values. An exploration of the concepts of machine learning, along with recent research developments in healthcare sectors.
Machine Learning for Medical Image Reconstruction: Second International Workshop, MLMIR 2019, Held in Conjunction with MICCAI 2019, Shenzhen, China, October 17, 2019, Proceedings (Lecture Notes in Computer Science #11905)
by Daniel Rueckert Andreas Maier Florian Knoll Jong Chul YeThis book constitutes the refereed proceedings of the Second International Workshop on Machine Learning for Medical Reconstruction, MLMIR 2019, held in conjunction with MICCAI 2019, in Shenzhen, China, in October 2019. The 24 full papers presented were carefully reviewed and selected from 32 submissions. The papers are organized in the following topical sections: deep learning for magnetic resonance imaging; deep learning for computed tomography; and deep learning for general image reconstruction.
Machine Learning for Multimodal Healthcare Data: First International Workshop, ML4MHD 2023, Honolulu, Hawaii, USA, July 29, 2023, Proceedings (Lecture Notes in Computer Science #14315)
by Julia A. Schnabel Andreas K. Maier Pallavi Tiwari Oliver StegleThis book constitutes the proceedings of the First International Workshop on Machine Learning for Multimodal Healthcare Date, ML4MHD 2023, held in Honolulu, Hawaii, USA, in July 2023. The 18 full papers presented were carefully reviewed and selected from 30 submissions. The workshop's primary objective was to bring together experts from diverse fields such as medicine, pathology, biology, and machine learning. With the aim to present novel methods and solutions that address healthcare challenges, especially those that arise from the complexity and heterogeneity of patient data.
Machine Learning for Neurodegenerative Disorders: Advancements and Applications (Artificial Intelligence in Biomedical Image Processing)
by Sudip Paul Sanjay Saxena Biswajit JenaThis book explores the application of machine learning to the understanding, early diagnosis, and management of neurodegenerative disorders. With a specific focus on its role in ongoing clinical trials, the book covers essential topics such as data collection, pre-processing, feature extraction, model development, and validation techniques. It delves into the applications of neuroimaging techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) in the diagnosis and understanding of neurodegenerative disorders. Additionally, the book examines various machine-learning algorithms employed for biomarker discovery in neurodegenerative disorders. It highlights the role of neuroinformatics and big data analysis in advancing the understanding and management of neurodegenerative disorders. Furthermore, the book reviews future prospects and presents the ethical considerations and regulatory challenges associated with implementing machine learning approaches in the diagnosis, treatment, and prevention of neurodegenerative disorders. This comprehensive resource is intended for neuroscientists, students, researchers, and neurologists to understand the emerging scope of machine learning in neurodegenerative disorders.
Machine Learning for Neuroscience: A Systematic Approach
by Chuck EasttomThis book addresses the growing need for machine learning and data mining in neuroscience. The book offers a basic overview of the neuroscience, machine learning and the required math and programming necessary to develop reliable working models. The material is presented in a easy to follow user-friendly manner and is replete with fully working machine learning code. Machine Learning for Neuroscience: A Systematic Approach, tackles the needs of neuroscience researchers and practitioners that have very little training relevant to machine learning. The first section of the book provides an overview of necessary topics in order to delve into machine learning, including basic linear algebra and Python programming. The second section provides an overview of neuroscience and is directed to the computer science oriented readers. The section covers neuroanatomy and physiology, cellular neuroscience, neurological disorders and computational neuroscience. The third section of the book then delves into how to apply machine learning and data mining to neuroscience and provides coverage of artificial neural networks (ANN), clustering, and anomaly detection. The book contains fully working code examples with downloadable working code. It also contains lab assignments and quizzes, making it appropriate for use as a textbook. The primary audience is neuroscience researchers who need to delve into machine learning, programmers assigned neuroscience related machine learning projects and students studying methods in computational neuroscience.
Machine Learning for Practical Decision Making: A Multidisciplinary Perspective with Applications from Healthcare, Engineering and Business Analytics (International Series in Operations Research & Management Science #334)
by Hossam Ali-Hassan Christo El Morr Manar Jammal Walid EI-HallakThis book provides a hands-on introduction to Machine Learning (ML) from a multidisciplinary perspective that does not require a background in data science or computer science. It explains ML using simple language and a straightforward approach guided by real-world examples in areas such as health informatics, information technology, and business analytics. The book will help readers understand the various key algorithms, major software tools, and their applications. Moreover, through examples from the healthcare and business analytics fields, it demonstrates how and when ML can help them make better decisions in their disciplines. The book is chiefly intended for undergraduate and graduate students who are taking an introductory course in machine learning. It will also benefit data analysts and anyone interested in learning ML approaches.
Machine Learning in Biological Sciences: Updates and Future Prospects
by Shyamasree Ghosh Rathi DasguptaThis book gives an overview of applications of Machine Learning (ML) in diverse fields of biological sciences, including healthcare, animal sciences, agriculture, and plant sciences. Machine learning has major applications in process modelling, computer vision, signal processing, speech recognition, and language understanding and processing and life, and health sciences. It is increasingly used in understanding DNA patterns and in precision medicine. This book is divided into eight major sections, each containing chapters that describe the application of ML in a certain field. The book begins by giving an introduction to ML and the various ML methods. It then covers interesting and timely aspects such as applications in genetics, cell biology, the study of plant-pathogen interactions, and animal behavior. The book discusses computational methods for toxicity prediction of environmental chemicals and drugs, which forms a major domain of research in the field of biology. It is of relevance to post-graduate students and researchers interested in exploring the interdisciplinary areas of use of machine learning and deep learning in life sciences.
Machine Learning in Clinical Neuroscience: Foundations and Applications (Acta Neurochirurgica Supplement #134)
by Luca Regli Victor E. Staartjes Carlo SerraThis book bridges the gap between data scientists and clinicians by introducing all relevant aspects of machine learning in an accessible way, and will certainly foster new and serendipitous applications of machine learning in the clinical neurosciences. Building from the ground up by communicating the foundational knowledge and intuitions first before progressing to more advanced and specific topics, the book is well-suited even for clinicians without prior machine learning experience. Authored by a wide array of experienced global machine learning groups, the book is aimed at clinicians who are interested in mastering the basics of machine learning and who wish to get started with their own machine learning research. The volume is structured in two major parts: The first uniquely introduces all major concepts in clinical machine learning from the ground up, and includes step-by-step instructions on how to correctly develop and validate clinical prediction models. It also includes methodological and conceptual foundations of other applications of machine learning in clinical neuroscience, such as applications of machine learning to neuroimaging, natural language processing, and time series analysis. The second part provides an overview of some state-of-the-art applications of these methodologies. The Machine Intelligence in Clinical Neuroscience (MICN) Laboratory at the Department of Neurosurgery of the University Hospital Zurich studies clinical applications of machine intelligence to improve patient care in clinical neuroscience. The group focuses on diagnostic, prognostic and predictive analytics that aid in decision-making by increasing objectivity and transparency to patients. Other major interests of our group members are in medical imaging, and intraoperative applications of machine vision.
Machine Learning in Dentistry
by Li Wang Dinggang Shen Ching-Chang KoThis book reviews all aspects of the use of machine learning in contemporary dentistry, clearly explaining its significance for dental imaging, oral diagnosis and treatment, dental designs, and dental research. Machine learning is an emerging field of artificial intelligence research and practice in which computer agents are employed to improve perception, cognition, and action based on their ability to “learn”, for example through use of big data techniques. Its application within dentistry is designed to promote personalized and precision patient care, with enhancement of diagnosis and treatment planning. In this book, readers will find up-to-date information on different machine learning tools and their applicability in various dental specialties. The selected examples amply illustrate the opportunities to employ a machine learning approach within dentistry while also serving to highlight the associated challenges. Machine Learning in Dentistry will be of value for all dental practitioners and researchers who wish to learn more about the potential benefits of using machine learning techniques in their work.
Machine Learning in Farm Animal Behavior using Python
by Natasa Kleanthous Abir HussainThis book is a comprehensive guide to applying machine learning to animal behavior analysis, focusing on activity recognition in farm animals. It begins by introducing key concepts of animal behavior and ethology, followed by an exploration of machine learning techniques, including supervised, unsupervised, semi-supervised, and reinforcement learning. The practical section covers essential steps like data collection, preprocessing, exploratory data analysis, feature extraction, model training, and evaluation, using Python.The book emphasizes the importance of high-quality data and discusses various sensors and annotation methods for effective data collection. It addresses key machine learning challenges such as generalization and data issues. Advanced topics include feature selection, model selection, hyperparameter tuning, and deep learning algorithms. Practical examples and Python implementations are provided throughout, offering hands-on experience for researchers, students, and professionals aiming to apply machine learning to animal behavior analysis.
Machine Learning in Healthcare Informatics
by Sumeet Dua U. Rajendra Acharya Prerna DuaThe book is a unique effort to represent a variety of techniques designed to represent, enhance, and empower multi-disciplinary and multi-institutional machine learning research in healthcare informatics. The book provides a unique compendium of current and emerging machine learning paradigms for healthcare informatics and reflects the diversity, complexity and the depth and breath of this multi-disciplinary area. The integrated, panoramic view of data and machine learning techniques can provide an opportunity for novel clinical insights and discoveries.
Machine Learning in Healthcare: Fundamentals and Recent Applications
by G.R. Sinha Bikesh Kumar SinghArtificial intelligence (AI) and machine learning (ML) techniques play an important role in our daily lives by enhancing predictions and decision-making for the public in several fields such as financial services, real estate business, consumer goods, social media, etc. Despite several studies that have proved the efficacy of AI/ML tools in providing improved healthcare solutions, it has not gained the trust of health-care practitioners and medical scientists. This is due to poor reporting of the technology, variability in medical data, small datasets, and lack of standard guidelines for application of AI. Therefore, the development of new AI/ML tools for various domains of medicine is an ongoing field of research. Machine Learning in Healthcare: Fundamentals and Recent Applications discusses how to build various ML algorithms and how they can be applied to improve healthcare systems. Healthcare applications of AI are innumerable: medical data analysis, early detection and diagnosis of disease, providing objective-based evidence to reduce human errors, curtailing inter- and intra-observer errors, risk identification and interventions for healthcare management, real-time health monitoring, assisting clinicians and patients for selecting appropriate medications, and evaluating drug responses. Extensive demonstrations and discussion on the various principles of machine learning and its application in healthcare is provided, along with solved examples and exercises. This text is ideal for readers interested in machine learning without any background knowledge and looking to implement machine-learning models for healthcare systems.
Machine Learning in Medical Imaging
by Qian Wang Li Wang Ehsan Adeli Yinghuan Shi Heung-Il SukThis book constitutes the refereed proceedings of the 7th International Workshop on Machine Learning in Medical Imaging, MLMI 2016, held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 38 full papers presented in this volume were carefully reviewed and selected from 60 submissions. The main aim of this workshop is to help advance scientific research within the broad field of machine learning in medical imaging. The workshop focuses on major trends and challenges in this area, and presents works aimed to identify new cutting-edge techniques and their use in medical imaging.
Machine Learning in Medical Imaging: 7th International Workshop, MLMI 2016, Held in Conjunction with MICCAI 2016, Athens, Greece, October 17, 2016, Proceedings (Lecture Notes in Computer Science #10019)
by Li Wang, Ehsan Adeli, Qian Wang, Yinghuan Shi and Heung-Il SukThis book constitutes the refereed proceedings of the 7th International Workshop on Machine Learning in Medical Imaging, MLMI 2016, held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 38 full papers presented in this volume were carefully reviewed and selected from 60 submissions. The main aim of this workshop is to help advance scientific research within the broad field of machine learning in medical imaging. The workshop focuses on major trends and challenges in this area, and presents works aimed to identify new cutting-edge techniques and their use in medical imaging.
Machine Learning in Medical Imaging: 8th International Workshop, MLMI 2017, Held in Conjunction with MICCAI 2017, Quebec City, QC, Canada, September 10, 2017, Proceedings (Lecture Notes in Computer Science #10541)
by Qian Wang, Yinghuan Shi, Heung-Il Suk and Kenji SuzukiThis book constitutes the refereed proceedings of the 8th International Workshop on Machine Learning in Medical Imaging, MLMI 2017, held in conjunction with MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 44 full papers presented in this volume were carefully reviewed and selected from 63 submissions. The main aim of this workshop is to help advance scientific research within the broad field of machine learning in medical imaging. The workshop focuses on major trends and challenges in this area, and presents works aimed to identify new cutting-edge techniques and their use in medical imaging.
Machine Learning in Medical Imaging: 9th International Workshop, MLMI 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Proceedings (Lecture Notes in Computer Science #11046)
by Yinghuan Shi Heung-Il Suk Mingxia LiuThis book constitutes the proceedings of the 9th International Workshop on Machine Learning in Medical Imaging, MLMI 2018, held in conjunction with MICCAI 2018 in Granada, Spain, in September 2018.The 45 papers presented in this volume were carefully reviewed and selected from 82 submissions. They focus on major trends and challenges in the area of machine learning in medical imaging and aim to identify new cutting-edge techniques and their use in medical imaging.
Machine Learning in Medicine
by Aeilko H. Zwinderman Ton J. CleophasMachine learning is a novel discipline concerned with the analysis of large and multiple variables data. It involves computationally intensive methods, like factor analysis, cluster analysis, and discriminant analysis. It is currently mainly the domain of computer scientists, and is already commonly used in social sciences, marketing research, operational research and applied sciences. It is virtually unused in clinical research. This is probably due to the traditional belief of clinicians in clinical trials where multiple variables are equally balanced by the randomization process and are not further taken into account. In contrast, modern computer data files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required. This book was written as a hand-hold presentation accessible to clinicians, and as a must-read publication for those new to the methods.
Machine Learning in Medicine (Chapman & Hall/CRC Healthcare Informatics Series)
by Jasjit S. Suri Ayman El-BazMachine Learning in Medicine covers the state-of-the-art techniques of machine learning and their applications in the medical field. It presents several computer-aided diagnosis (CAD) systems, which have played an important role in the diagnosis of several diseases in the past decade, e.g., cancer detection, resulting in the development of several successful systems. New developments in machine learning may make it possible in the near future to develop machines that are capable of completely performing tasks that currently cannot be completed without human aid, especially in the medical field. This book covers such machines, including convolutional neural networks (CNNs) with different activation functions for small- to medium-size biomedical datasets, detection of abnormal activities stemming from cognitive decline, thermal dose modelling for thermal ablative cancer treatments, dermatological machine learning clinical decision support systems, artificial intelligence-powered ultrasound for diagnosis, practical challenges with possible solutions for machine learning in medical imaging, epilepsy diagnosis from structural MRI, Alzheimer's disease diagnosis, classification of left ventricular hypertrophy, and intelligent medical language understanding. This book will help to advance scientific research within the broad field of machine learning in the medical field. It focuses on major trends and challenges in this area and presents work aimed at identifying new techniques and their use in biomedical analysis, including extensive references at the end of each chapter.
Machine Learning in Medicine - Cookbook
by Aeilko H. Zwinderman Ton J. CleophasThe amount of data in medical databases doubles every 20 months, and physicians are at a loss to analyze them. Also, traditional methods of data analysis have difficulty to identify outliers and patterns in big data and data with multiple exposure / outcome variables and analysis-rules for surveys and questionnaires, currently common methods of data collection, are, essentially, missing. Obviously, it is time that medical and health professionals mastered their reluctance to use machine learning and the current 100 page cookbook should be helpful to that aim. It covers in a condensed form the subjects reviewed in the 750 page three volume textbook by the same authors, entitled "Machine Learning in Medicine I-III" (ed. by Springer, Heidelberg, Germany, 2013) and was written as a hand-hold presentation and must-read publication. It was written not only to investigators and students in the fields, but also to jaded clinicians new to the methods and lacking time to read the entire textbooks. General purposes and scientific questions of the methods are only briefly mentioned, but full attention is given to the technical details. The two authors, a statistician and current president of the International Association of Biostatistics and a clinician and past-president of the American College of Angiology, provide plenty of step-by-step analyses from their own research and data files for self-assessment are available at extras. springer. com. From their experience the authors demonstrate that machine learning performs sometimes better than traditional statistics does. Machine learning may have little options for adjusting confounding and interaction, but you can add propensity scores and interaction variables to almost any machine learning method.
Machine Learning in Medicine - Cookbook Three
by Aeilko H. Zwinderman Ton J. CleophasUnique features of the book involve the following. 1. This book is the third volume of a three volume series of cookbooks entitled "Machine Learning in Medicine - Cookbooks One, Two, and Three". No other self-assessment works for the medical and health care community covering the field of machine learning have been published to date. 2. Each chapter of the book can be studied without the need to consult other chapters, and can, for the readership''s convenience, be downloaded from the internet. Self-assessment examples are available at extras. springer. com. 3. An adequate command of machine learning methodologies is a requirement for physicians and other health workers, particularly now, because the amount of medical computer data files currently doubles every 20 months, and, because, soon, it will be impossible for them to take proper data-based health decisions without the help of machine learning. 4. Given the importance of knowledge of machine learning in the medical and health care community, and the current lack of knowledge of it, the readership will consist of any physician and health worker. 5. The book was written in a simple language in order to enhance readability not only for the advanced but also for the novices. 6. The book is multipurpose, it is an introduction for ignorant, a primer for the inexperienced, and a self-assessment handbook for the advanced. 7. The book, was, particularly, written for jaded physicians and any other health care professionals lacking time to read the entire series of three textbooks. 8. Like the other two cookbooks it contains technical descriptions and self-assessment examples of 20 important computer methodologies for medical data analysis, and it, largely, skips the theoretical and mathematical background. 9. Information of theoretical and mathematical background of the methods described are displayed in a "notes" section at the end of each chapter. 10. Unlike traditional statistical methods, the machine learning methodologies are able to analyze big data including thousands of cases and hundreds of variables. 11. The medical and health care community is little aware of the multidimensional nature of current medical data files, and experimental clinical studies are not helpful to that aim either, because these studies, usually, assume that subgroup characteristics are unimportant, as long as the study is randomized. This is, of course, untrue, because any subgroup characteristic may be vital to an individual at risk. 12. To date, except for a three volume introductary series on the subject entitled "Machine Learning in Medicine Part One, Two, and Thee, 2013, Springer Heidelberg Germany" from the same authors, and the current cookbook series, no books on machine learning in medicine have been published. 13. Another unique feature of the cookbooks is that it was jointly written by two authors from different disciplines, one being a clinician/clinical pharmacologist, one being a mathematician/biostatistician. 14. The authors have also jointly been teaching at universities and institutions throughout Europe and the USA for the past 20 years. 15. The authors have managed to cover the field of medical data analysis in a nonmathematical way for the benefit of medical and health workers. 16. The authors already successfully published many statistics textbooks and self-assessment books, e. g. , the 67 chapter textbook entitled "Statistics Applied to Clinical Studies 5th Edition, 2012, Springer Heidelberg Germany" with downloads of 62,826 copies. 17. The current cookbook makes use, in addition to SPSS statistical software, of various free calculators from the internet, as well as the Konstanz Information Miner (Knime), a widely approved free machine learning package, and the free Weka Data Mining package from New Zealand. 18. The above software packages with hundreds of nodes, the basic processing units including virtually all of the statistical and data mining methods, can be used not only for data analyses, but also for appropriate data stora...
Machine Learning in Medicine - Cookbook Two
by Aeilko H. Zwinderman Ton J. CleophasThe amount of data medical databases doubles every 20 months, and physicians are at a loss to analyze them. Also, traditional data analysis has difficulty to identify outliers and patterns in big data and data with multiple exposure / outcome variables and analysis-rules for surveys and questionnaires, currently common methods of data collection, are, essentially, missing. Consequently, proper data-based health decisions will soon be impossible. Obviously, it is time that medical and health professionals mastered their reluctance to use machine learning methods and this was the main incentive for the authors to complete a series of three textbooks entitled "Machine Learning in Medicine Part One, Two and Three, Springer Heidelberg Germany, 2012-2013", describing in a nonmathematical way over sixty machine learning methodologies, as available in SPSS statistical software and other major software programs. Although well received, it came to our attention that physicians and students often lacked time to read the entire books, and requested a small book, without background information and theoretical discussions and highlighting technical details. For this reason we produced a 100 page cookbook, entitled "Machine Learning in Medicine - Cookbook One", with data examples available at extras. springer. com for self-assessment and with reference to the above textbooks for background information. Already at the completion of this cookbook we came to realize, that many essential methods were not covered. The current volume, entitled "Machine Learning in Medicine - Cookbook Two" is complementary to the first and also intended for providing a more balanced view of the field and thus, as a must-read not only for physicians and students, but also for any one involved in the process and progress of health and health care. Similarly to Machine Learning in Medicine - Cookbook One, the current work will describe stepwise analyses of over twenty machine learning methods, that are, likewise, based on the three major machine learning methodologies: Cluster methodologies (Chaps. 1-3) Linear methodologies (Chaps. 4-11) Rules methodologies (Chaps. 12-20) In extras. springer. com the data files of the examples are given, as well as XML (Extended Mark up Language), SPS (Syntax) and ZIP (compressed) files for outcome predictions in future patients. In addition to condensed versions of the methods, fully described in the above three textbooks, an introduction is given to SPSS Modeler (SPSS' data mining workbench) in the Chaps. 15, 18, 19, while improved statistical methods like various automated analyses and Monte Carlo simulation models are in the Chaps. 1, 5, 7 and 8. We should emphasize that all of the methods described have been successfully applied in practice by the authors, both of them professors in applied statistics and machine learning at the European Community College of Pharmaceutical Medicine in Lyon France. We recommend the current work not only as a training companion to investigators and students, because of plenty of step by step analyses given, but also as a brief introductory text to jaded clinicians new to the methods. For the latter purpose, background and theoretical information have been replaced with the appropriate references to the above textbooks, while single sections addressing "general purposes", "main scientific questions" and "conclusions" are given in place. Finally, we will demonstrate that modern machine learning performs sometimes better than traditional statistics does. Machine learning may have little options for adjusting confounding and interaction, but you can add propensity scores and interaction variables to almost any machine learning method.
Machine Learning in Medicine – A Complete Overview
by Aeilko H. Zwinderman Ton J. CleophasAdequate health and health care is no longer possible without proper data supervision from modern machine learning methodologies like cluster models, neural networks, and other data mining methodologies. The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector, and it was written as a training companion, and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care.In this second edition the authors have removed the textual errors from the first edition. Also, the improved tables from the first edition, have been replaced with the original tables from the software programs as applied. This is, because, unlike the former, the latter were without error, and readers were better familiar with them.The main purpose of the first edition was, to provide stepwise analyses of the novel methods from data examples, but background information and clinical relevance information may have been somewhat lacking. Therefore, each chapter now contains a section entitled "Background Information".Machine learning may be more informative, and may provide better sensitivity of testing than traditional analytic methods may do. In the second edition a place has been given for the use of machine learning not only to the analysis of observational clinical data, but also to that of controlled clinical trials.Unlike the first edition, the second edition has drawings in full color providing a helpful extra dimension to the data analysis.Several machine learning methodologies not yet covered in the first edition, but increasingly important today, have been included in this updated edition, for example, negative binomial and Poisson regressions, sparse canonical analysis, Firth's bias adjusted logistic analysis, omics research, eigenvalues and eigenvectors.