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Neglected No More: The Urgent Need to Improve the Lives of Canada's Elders in the Wake of a Pandemic
by Andre PicardIt took the coronavirus pandemic to open our eyes to the deplorable state of so many of the nation's long-term care homes: the inhumane conditions, overworked and underpaid staff, and lack of oversight. In this timely new book, esteemed health reporter André Picard reveals the full extent of the crisis in eldercare, and offers an urgently needed prescription to fix a broken system.When COVID-19 spread through seniors' residences across Canada, the impact was horrific. Along with widespread illness and a devastating death toll, the situation exposed a decades-old crisis: the shocking systemic neglect towards our elders.Called in to provide emergency care in some of the hardest-hit facilities in Ontario and Quebec, the military issued damning reports of what they encountered. And yet, the failings that were exposed--unappetizing meals, infrequent baths, overmedication, physical abuse and inadequate personal care--have persisted for years in these institutions. In Neglected No More, André Picard takes a hard look at how we came to embrace mass institutionalization, and lays out what can and must be done to improve the state of care for our elders, a highly vulnerable population with complex needs and little ability to advocate for themselves. Picard shows that the entire eldercare system--fragmented, underfunded and unsupported--is long overdue for a fundamental rethink. We need to find ways to ensure seniors can age gracefully in the community for longer, with supportive home care and respite for family caregivers, and ensure that long-term care homes are not warehouses of isolation and neglect. Our elders deserve nothing less.
Neglected Tropical Diseases: Drug Discovery and Development (Methods and Principles in Medicinal Chemistry)
by Raimund Mannhold Helmut Buschmann Jörg HolenzA drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products. This important book: -Ties together information from different sources for developing novel treatsments forneglected tropical diseases -Is aligned with WHO?s initiative to eradicate tropical diseases -Outlines current and potential drugs for treating tropical diseases -Provides a standard reference for the entire field Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.
Neglected Tropical Diseases and Conditions of the Nervous System
by Marina Bentivoglio Esper A. Cavalheiro Krister Kristensson Nilesh B. PatelA number of diseases and conditions that occur primarily in remote rural or poor urban areas of low-income countries have traditionally been neglected by the neuroscience research community. These diseases and conditions affect the nervous system directly (sometimes with lethal consequences) and/or are associated with severe neurological sequels such as epilepsy, cognitive deficits, and sleep disruption. Several diseases also have the effect of promoting poverty by leaving sufferers unable to lead economically productive lives due to cognitive and behavioral disturbances or severe stigmatization. The pathogenesis of neural dysfunction in the diseases addressed in this book and their sequels remains unclear. Neuroscience of Neglected Diseases and Conditions makes available much needed information about how these diseases affect the human nervous system as well as to promote interest in further research. Further research into neglected diseases and conditions will uncover information that sheds light on more general topics of interest to the neuroscience research community.
Neglected Tropical Diseases and Phytochemicals in Drug Discovery
by Chukwuebuka Egbuna Muhammad Akram Jonathan Chinenye Ifemeje Samrat BhattacharyyaNEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.
Neglected Tropical Diseases - East Asia (Neglected Tropical Diseases)
by Jürg Utzinger Peiling Yap Martin Bratschi Peter SteinmannNeglected tropical diseases (NTDs) are a group of diseases frequently found in impoverished communities in tropical and sub-tropical countries. The risk for many of the NTDs is high in both deprived urban and rural areas of East Asia. Adapted to the endemic settings and characteristics of the diseases, a range of tools and strategies are currently being rolled out for the large-scale control of many NTDs. Both vector control measures and community sensitization programmes have for example been used to control dengue in urbanized settings. Challenges posed by yaws and lymphatic filariasis are being addressed by mass drug administration, while rabies requires the involvement of the veterinary public health sector for disease control. For leprosy, an elimination target has been defined; however, achieving this goal remains a considerable challenge. Food-borne trematodiases, on the other hand, are emerging and require a deeper understanding of its burden in East Asia and how these diseases can be tackled in a cost-effective manner. Finally, factors, such as an increase of non-communicable diseases due to changing lifestyles which accompany economic growth, the spreading HIV epidemic as well as climate change and the occurrence of natural disasters can potentially affect the epidemiology and control of NTDs. This volume discusses the mentioned topics in detail with contributions by experts in the respective research areas from different working environments.
Neglected Tropical Diseases - Europe and Central Asia (Neglected Tropical Diseases)
by Jürg Utzinger Peter SteinmannThis volume of the Neglected Tropical Diseases (NTD) series covers the most prevalent NTDs in Europe and Central Asia. This book discusses in detail the pathology, diagnostics and control approaches of the most important neglected pathogens occurring in these geographical regions. Each chapter focuses on one specific disease or group of related diseases, and provides the reader with in-depth insights into the topic. This volume addresses researchers in Microbiology and Biomedicine as well as clinicians and public health officials working in affected regions.
Neglected Tropical Diseases - Latin America and the Caribbean
by Carlos Franco-Paredes José Ignacio Santos-PreciadoThis book addresses the major neglected tropical diseases (NTDs) - based on their prevalence and the years of healthy life lost to disability - in Latin American and Caribbean countries. These include Chagas disease, leishmaniasis, hookworm infection, and other soil-transmitted helminth infections, followed by dengue, schistosomiasis, leishmaniasis, leprosy, cysticercosis, bartonellosis, Plasmodium vivax malaria, and onchocerciasis. Topics like disease burden, major manifestations and approaches to the control and elimination of NTDs in Latin America and the Caribbean are discussed in detail. As such, the book will be of general interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of this region of the world.
Neglected Tropical Diseases - Middle East and North Africa
by Mary Ann Mcdowell Sima RafatiThe Middle East and North Africa (MENA) is highly endemic for several neglected tropical diseases (NTDs), including viral, bacterial, protozoan and helminth infections. This new volume covers the most prevalent NTDs found in about 22 MENA countries emphasizing the disease burden, clinical manifestations and control approaches. Each individual chapter deals with one specific disease and is written by a group of experts on that topic.
Neglected Tropical Diseases - North America (Neglected Tropical Diseases)
by Jill E. WeatherheadThis volume of the Neglected Tropical Diseases (NTD) series covers the most prevalent NTDs in North America. This book discusses in detail pathology, diagnostics and control approaches of selected NTDs in the sub-tropical regions of the United States of America. There are disproportionate numbers of children and adults living in poverty within the United States that are at risk of infections caused by helminths, protozoa, viruses and bacteria which commonly lead to chronic, debilitating and stigmatizing diseases. Each chapter focuses on one specific disease or series of related diseases, and provides in-depth insights into the topic.
Neglected Tropical Diseases - Oceania
by Alex LoukasThis volume of the Neglected Tropical Diseases (NTD) series covers the most prevalent NTDs in Oceania. This book will discuss in detail pathology, diagnostics and control approaches of selected NTDs in the geografic region. A large part of Oceania's population lives in poverty and therefore is at high risk for certain parasitic diseases, such as hookworm infection, lymphatic filariasis, strongyloidiasis or scabies. In addition bacterial infections such as dengue and new emerging viruses are of importance as major health risks for people living and traveling in this area. Each chapter focuses on one specific disease or series of related diseases, and provides in-depth insights into the topic.
Neglected Tropical Diseases - South Asia (Neglected Tropical Diseases Ser.)
by Sunit K. SinghThis book covers all aspects of Neglected Tropical Diseases in the region of South Asia. NTDs constitute a significant part of the total disease burden in this geographic area, including soil borne helminth infections, vector borne viral infections, protozoan infections and a few bacterial infections. The current volume covers the most common neglected viral, bacterial and protozoan infections. On top of that, the last part of the volume is dedicated to the management of neglected tropical diseases.
Neglected Tropical Diseases - Sub-Saharan Africa
by John Gyapong Boakye BoatinThis book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.
Negotiating a Good Death: Euthanasia in the Netherlands
by Carlton Muson Joan K PerryShould human beings be allowed to decide when to die? Should doctors be allowed to assist them?During the last ten years there has been much international interest in euthanasia in the Netherlands. In the discussion of euthanasia in the US and the UK, both sides in the debate continually refer to the “Dutch Experience”. Negotiating a Good Death: Euthanasia in the Netherlands presents firsthand descriptions of euthanasia in practice in the Netherlands--something that has never been done before. This will provide a deeper understanding of the issues involved for all those interested in end-of-life decisions. It will also help clinicians and other medical professionals better understand end-of-life decision making.Negotiating a Good Death is the first inside account of how decisions about euthanasia are made in real-life situations. Documenting two years of observations at a Dutch hospital, this valuable book describes why patients request euthanasia, the social factors that influence doctors’decisions about granting patients’requests, and how patients and doctors confer over peaceful deaths. Some aspects of this delicate, often hidden, and socially taboo subject that Negotiating a Good Death frankly discusses are: the emotions that lead to a wish for death the ideology of easy death the anthropology of death the role of the researcher the line between symptom alleviation and euthanasia where the responsibility lies conservative options for medical personnel how to speak to relatives of someone who has requested euthanasia euthanasia as a cultural constructThrough case studies and examples, Negotiating a Good Death: Euthanasia in the Netherlands will help you understand the issues surrounding euthanasia and how life-ending decisions are made by both doctors and patients.
Negotiating a Good Death: Euthanasia in the Netherlands
by Joan K Parry Carlton MunsonSocial Work Theory and Practice with the Terminally Ill, second edition, takes a compassionate look at ways that social workers can help dying people and their families. The social workers who work most effectively with terminally ill patients and their families are the ones who best understand the multifaceted nature of the dying process and its impact on the the patient, the family, and even on the health care professionals who work with patients at the end of life. Dr. Parry--who specializes in dying and bereavement--offers astute observations on the stages of dealing with the diagnosis of a terminal illness and the impending death that patients and their families confront. This updated second edition provides valuable new information on ways that social workers can help those with AIDS and their families, on traumatic death from any cause, and on the grieving processes of parents.Social Work Theory and Practice with the Terminally Ill, second edition, also includes stimulating discussions on: the interdisciplinary health team the grieving process professional burnout how social workers adapt to working with dying patients euthanasia and physician-assisted dying living wills and patients’rightsIn touching case studies, this volume illustrates the particular needs and concerns of the terminally ill and their families--impending losses, financial worries, job concerns, pain, unfinished business, and spiritual needs--and reviews successful interventions used by social workers to help patients and their families work through the dying process.
Negotiating Ageing: Cultural Adaptation to the Prospect of a Long Life (Routledge Key Themes in Health and Society)
by Simon BiggsThe world is growing older and this is a historically unprecedented phenomenon. Negotiating such change, personally, socially and for governments and international organisations requires an act of cultural adaptation. Two key questions arise: What is the purpose of a long life? and How do we adapt to societies where generations are of approximately the same size? A number of pre-existing narratives can be identified; however, it is argued that contemporary policies have produced a premature answer which may eclipse the potential arising from lifecourse change. In this book Simon Biggs discusses ways of interrogating these questions and the adaptations we make to them. Four major areas, all of which have been suggested as solutions to population ageing, are critically assessed, including work as an answer, the relationship between work, ageing and health, narratives of spirit, belief and wisdom, the body and the natural, anti-ageing medicine, critical approaches to dementia, plus family and intergenerational relations. This book is particiularly useful for those trying to make sense of population ageing and negotiate solutions. It describes a number of concepts that can be used to assess what we are told about a long life and how generations can adapt together. With the cultural landscape moving away from traditional interpretations of old age, the question of adult ageing is of growing interest to a number of groups. This book is essential reading for social and health-care workers, other helping professionals, policy makers, social scientists and all who encounter the prospect of a long life.
Negotiating Family Responsibilities
by Janet Finch Professor Janet Finch Jennifer MasonNegotiating Family Responsibilities provides a major new insight into contemporary family life, particularly kin relationships outside the nuclear family. While many people believe that the real meaning of 'family' has shrunk to the nuclear family household, there is considerable evidence to suggest that relationships with the wider kin group remain an important part of most people's lives. Based on the findings of a major study of kinship, and including lively verbatim accounts of conversations with family members concepts of responsibility and obligation within family life are examined and the authors expand theories on the nature of assistance within families and argue that it is negotiated over time rather than given automatically.
Negotiating Health: Intellectual Property and Access to Medicines
by Pedro Roffe Geoff Tansey David Vivas-EuguiIn developing countries, access to affordable medicines for the treatment of diseases such as AIDS and malaria remains a matter of life or death. In Africa, for instance, more than one million children die each year from malaria alone, a figure which could soon be far higher with the extension of patent rules for pharmaceuticals. Previously, access to essential medicines was made possible by the supply of much cheaper generics, manufactured largely by India; from 2005, however, the availability of these drugs is threatened as new WTO rules take effect. Halting the spread of malaria and HIV/AIDS is one of the eight Millennium Goals adopted at the UN Millennium Summit, which makes this a timely and topical book. Informed analysis is provided by internationally renowned contributors who look at the post-2005 world and discuss how action may be taken to ensure that intellectual property regimes are interpreted and implemented in a manner supportive to the right to protect public health and, in particular, to promote access to medicines for all.
Negotiating Pharmaceutical Uncertainty: Women's Agency in a South African HIV Prevention Trial
by Eirik Saethre Jonathan StadlerTelling the story of a clinical trial testing an innovative gel designed to prevent women from contracting HIV, Negotiating Pharmaceutical Uncertainty provides new insight into the complex and contradictory relationship between medical researchers and their subjects. Although clinical trials attempt to control and monitor participants' bodies, Saethre and Stadler argue that the inherent uncertainty of medical testing can create unanticipated opportunities for women to exercise control over their health, sexuality, and social relationships. Combining a critical analysis of the social production of biomedical knowledge and technologies with a detailed ethnography of the lives of female South African trial participants, this book brings to light issues of economic exclusion, racial disparity, and spiritual insecurity in Johannesburg's townships. Built on a series of tales ranging from strategy sessions at the National Institutes of Health to witchcraft accusations against the trial, Negotiating Pharmaceutical Uncertainty illuminates the everyday social lives of clinical trials.As embedded anthropologists, Saethre and Stadler provide a unique and nuanced perspective of the reality of a clinical trial that is often hidden from view.
Negotiating Pharmaceutical Uncertainty: Women's Agency in a South African HIV Prevention Trial
by Eirik Saethre Jonathan StadlerTelling the story of a clinical trial testing an innovative gel designed to prevent women from contracting HIV, Negotiating Pharmaceutical Uncertainty provides new insight into the complex and contradictory relationship between medical researchers and their subjects. Although clinical trials attempt to control and monitor participants' bodies, Saethre and Stadler argue that the inherent uncertainty of medical testing can create unanticipated opportunities for women to exercise control over their health, sexuality, and social relationships. Combining a critical analysis of the social production of biomedical knowledge and technologies with a detailed ethnography of the lives of female South African trial participants, this book brings to light issues of economic exclusion, racial disparity, and spiritual insecurity in Johannesburg's townships. Built on a series of tales ranging from strategy sessions at the National Institutes of Health to witchcraft accusations against the trial, Negotiating Pharmaceutical Uncertainty illuminates the everyday social lives of clinical trials. As embedded anthropologists, Saethre and Stadler provide a unique and nuanced perspective of the reality of a clinical trial that is often hidden from view.
Negotiating Public Health in a Globalized World
by David Fairman Diana Chigas Nick Drager Elizabeth McclintockIn a new era of global health diplomacy, the most important tool for decision-making is negotiation. Globalization is binding countries, issues and people together as never before. In the domain of public health, traditional international concerns like the spread of infectious diseases have been joined by new concerns and challenges in managing the health impacts of trade and intellectual property rights, and by new opportunities to create effective global public health agreements and programs. To address the major health crises of today and to prevent or mitigate them in the future, countries must seek collective agreement and action within and across their borders. However, the world of international negotiation is not the world in which health decision-makers reside or are most comfortable. The goal of this guide is to provide health policy-makers with practical information and negotiation tools, to help them create better international health agreements and programs. "This is the best book I know to help health professionals develop the negotiation skills necessary to meet the challenges of global health diplomacy. It is filled with wise advice and invaluable tools for success." Professor Jeswald W. Salacuse, The Fletcher School of Law and Diplomacy, Tufts University
Negotiating the Emotional Challenges of Conducting Deeply Personal Research in Health
by J. E. Sumerau Alexandra Xan" NowakowskiPublic health researchers and clinicians regularly work with people who have suffered physical and mental trauma. Knowing how to conduct a study or treat a patient while navigating deep emotional issues requires special skills and overall awareness of how trauma can impact the process and outcomes of participating in research and/or receiving health care. This book presents a diverse array of case examples from scholars of health-related topics, focusing on biographical narrative as a window into understanding key needs in trauma informed scholarship and medicine. Exploring stories from people of varied backgrounds, experiences, and contexts can help professionals within and beyond the academic research and clinical care spheres create rewarding experiences for patients. Negotiating the Emotional Challenges of Conducting Deeply Personal Research in Health will be of interest to public health practitioners, educators and researchers as well as students.
Neighborhoods, Communities and Child Maltreatment: A Global Perspective (Child Maltreatment #15)
by Kathryn Maguire-Jack Carmit KatzThis volume explores methods for studying child maltreatment in the context of neighborhoods and communities, given their importance in the lives of families. It discusses the ways in which neighborhoods have changed over time and how this that has impacted parenting in the modern context. It also highlights the ways in which policies have contributed to persistent poverty and inequality, which indirectly impacts child maltreatment. An important focus of this volume is to examine the multitude of ways in which the neighborhood context affects families, including structural factors like poverty, segregation, residential instability, and process factors like social cohesion. The volume takes a critical look at the ways in which culture and context affect maltreatment through a community-based approach, and uses this approach to understand child maltreatment in rural areas. The editors and contributors explore innovative prevention approaches and reflect on the future of this field in terms of what remains unknown, how the information should be used to guide policy in the future, and how practitioners can best support parents while being mindful of the importance of context. Addressing an important topic, this volume is of relevance and interest to a wide readership of scholars and students in the social and behavioral sciences, as well as to practitioners and policy makers working with neighborhoods and communities.
Neighbourhood Effects or Neighbourhood Based Problems?: A Policy Context
by Nick Bailey Duncan Maclennan Ludi Simpson Maarten Van Ham David ManleyThis edited volume critically examines the link between area based policies, neighbourhood based problems, and neighbourhood effects: the idea that living in disadvantaged neighbourhoods has a negative effect on residents' life chances over and above the effect of their individual characteristics. Over the last few decades, Western governments have persistently pursued area based policies to fight such effects, despite a lack of evidence that they exist, or that these policies make a difference. The first part of this book presents case studies of perceived neighbourhood based problems in the domains of crime; health; educational outcomes; and employment. The second part of the book presents an international overview of the policies that different governments have implemented in response to these neighbourhood based problems, and discusses the theoretical and conceptual processes behind place based policy making. Case studies are drawn from a diverse range of countries including the United Kingdom, The Netherlands, Australia, Canada, and the USA.
Neighbourhood Effects Research: New Perspectives
by Nick Bailey Duncan Maclennan Ludi Simpson Maarten Van Ham David ManleyOver the last 25 years a vast body of literature has been published on neighbourhood effects: the idea that living in more deprived neighbourhoods has a negative effect on residents' life chances over and above the effect of their individual characteristics. The volume of work not only reflects academic and policy interest in this topic, but also the fact that we are still no closer to answering the question of how important neighbourhood effects actually are. There is little doubt that these effects exist, but we do not know enough about the causal mechanisms which produce them, their relative importance in shaping individual's life chances, the circumstances or conditions under which they are most important, or the most effective policy responses. Collectively, the chapters in this book offer new perspectives on these questions, and refocus the academic debate on neighbourhood effects. The book enriches the neighbourhood effects literature with insights from a wide range of disciplines and countries.
Neighbourhood Structure and Health Promotion
by Christiane Stock Anne EllawayIt has long been theorized that people living in poor areas have more health problems than their more advantaged peers. More recently, science has been testing this hypothesis, concentrating on the impact of the built environment on well-being and its contribution to health inequities. Neighbourhood Structure and Health Promotion offers sociology-based theory and evidence-based findings so readers may better understand the effects of place on health choices, behaviour, and outcomes. This international volume analyzes the complex relationships among neighbourhood conditions and characteristics, people's perceptions of where they live, and their everyday health lives, from eating habits and activity levels to smoking, drinking, and drug use. Chapters introduce innovative methods for measuring and monitoring links between place and health in terms of risks and resources, and employing objective and subjective data. Prospects for engaging neighbourhoods in prevention efforts, particularly involving young people, and policy implications for the future of health promotion and inequity reduction are discussed as well. Included in the coverage: The spatiality of injustice: area effects on behaviour.Qualitative and quantitative methods for assessing neighbourhood health resources.The potential of GIS and GPS in the health sciences.Green spaces and health: possibilities for research and policy.School neighbourhoods and obesity prevention in youth.Connecting gender, social environment, and health.Neighbourhood Structure and Health Promotion advances the study of this increasingly critical topic, making it a valuable reference for researchers, practitioners, policy makers and advanced students in health, health promotion, social epidemiology, and urban planning.