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Modern Hip Preservation: New Insights In Pathophysiology And Surgical Treatment
by Reinhold GanzThis book comprehensively discusses both the history and the current concepts of modern hip preservation surgery. Offering an overview of the game-changing studies on the hip and pelvis vascular anatomy it thoroughly describes the evolution of a new and comprehensive pathophysiology of the hip joint degeneration. Moreover, in the first part, particular emphasis is devoted to the history and current knowledge of femoroacetabular impingement and hip dysplasia.The second part examines the main surgical procedures that have evolved and matured since the 1980s, culminating in a new class of open surgical approaches, such as hip surgical dislocation, periacetabular osteotomies, proximal femoral osteotomies and corrections, and widening the door for hip-arthroscopy. Based on over 40 years of practical and pioneering experience by the editor and 15 years of collaboration with the GICCA Study Group, this book offers a valuable resource to residents, researchers and practicing orthopedic surgeon wishing to gain insights into hip preservation surgery.
Modern Hip Resurfacing
by Derek J. McminnHip replacement surgery is a radical and traumatic procedure that has enormous disadvantages to the patient in terms of postoperative mobility and morbidity. Hip resurfacing is a more conservative approach resulting in less of the patient's hip and femur being lost, which has great advantages to a younger patient group. The author of Hip Resurfacing is the world's leading authority on this surgery, making this the definitive resource in hip resurfacing
Modern Hospice Design: The Architecture of Palliative and Social Care
by Ken WorpoleThe new edition of this acclaimed book comprehensively updates its timely advocacy of the need for good quality palliative care, today more necessary than ever. Rooted in the social history of the care of the elderly and terminally ill, Modern Hospice Design: The Architecture of Palliative and Social Care takes cognisance of the new conditions of social care in the 21st century, principally in the UK, Europe and North America. It does so with regard to the development of new building types, but also in response to new philosophies of palliative care and the status of the elderly and the dying. Benefitting from a clearer methodological approach and conceptual framework, the expanded book allows a broad section of readers to navigate the text more easily. At its core is a public discussion of a philosophy of design for providing care for the elderly and the vulnerable, taking the importance of architectural aesthetics, the use of quality materials, the porousness of design to the wider world, and the integration of indoor and outdoor spaces as part of the overall care environment. In doing so it advocates care settings that, in the words of Maggie Jencks whose life and ideas inspired the Maggie’s Centres, ‘rise to the occasion’. Including new chapters and new in-depth case studies, complete will full colour illustrations, this book is for architects and interior designers and their students, healthcare professionals, social care providers, estate and facility managers, hospital administrators and Healthcare Trust Boards.
Modern Immunohistochemistry
by Peiguo Chu Lawrence WeissDiagnostic pathology is an inherently flawed science due to the many possible interpretations of various tissues. However, the application of immunohistochemical stains as a diagnostic tool has been widely used since the 1990s as an extremely effective ancillary technique that removes much subjectivity from the practice. In fact, immunohistochemistry has supplanted simple morphologic evaluation as the definitive diagnostic method for a wide array of tumor types. This book offers a new and modern atlas-based resource for this science. Every anatomic region is covered in detail, and major diseases contain side-by-side examples of other ancillary staining techniques for comparison. The text is geared toward both the resident and practitioner of anatomic pathology and is supplemented with histograms, algorithms, and guides to the application and interpretation of uncommon antigens and immunostains. Not only is the book illustrated with more than 600 high-quality photomicrographs, but a companion CD-ROM of all images in downloadable format is included.
Modern Industrial Microbiology and Biotechnology
by Nduka Okafor Benedict C. OkekeThe field of industrial microbiology involves a thorough knowledge of the microbial physiology behind the processes in the large-scale, profit-oriented production of microbe-related goods which are the subject of the field. In recent times a paradigm shift has occurred, and a molecular understanding of the various processes by which plants, animals and microorganisms are manipulated is now central to industrial microbiology. Thus the various applications of industrial microbiology are covered broadly, with emphasis on the physiological and genomic principles behind these applications. Relevance of the new elements such as bioinformatics, genomics, proteomics, site-directed mutation and metabolic engineering, which have necessitated the paradigm shift in industrial microbiology are discussed.
Modern Infectious Disease Epidemiology
by Mirjam Kretzschmar Alexander Krämer Klaus KrickebergHardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro's and con's of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control. The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission. This choice of topics bridges the gap between scientific research on the clinical, biological, mathematical, social and economic aspects of infectious diseases and their applications in public health. The book will help the reader to understand the impact of infectious diseases on modern society and the instruments that policy makers have at their disposal to deal with these challenges. It is written for students of the health sciences, both of curative medicine and public health, and for experts that are active in these and related domains, and it may be of interest for the educated layman since the technical level is kept relatively low.
Modern Infectious Disease Epidemiology
by Johan GieseckeHighly practical yet authoritative, the new edition of Modern Infectious Disease Epidemiology has been thoroughly updated and revised in line with changing health concerns. This successful book continues to outline the tools available to the infectious disease student or clinician seeking a thorough background in the epidemiology of infectious and communicable diseases. Building on many case studies and practical scenarios included, the book then uses the tools learnt to illustrate the fundamental concepts of the study of infectious diseases, such as infection spread, surveillance and control, infectivity, incubation periods, seroepidemiology, and immunity in populations. New edition of this popular book, completely revised and updated Retains the clarity and down-to-earth approach praised in previous editions Successfully combines epidemiological theory with the principles of infectious disease treatment and control A highly experienced author brings a personal and unique approach to this important subject All students of epidemiology, infectious disease medicine and microbiology will find this text invaluable, ensuring its continued popularity.
Modern Issues and Methods in Biostatistics
by Mark ChangClassic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.
Modern Keratoplasty: Surgical Techniques and Indications (Essentials in Ophthalmology)
by Jorge L. Alió Jorge L. Alió del BarrioKeratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells.This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons.Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.
Modern Magnetic Resonance: Part 1: Applications In Chemistry, Biological And Marine Sciences, Part 2: Applications In Medical And Pharmaceutical Sciences, Part 3: Applications In Materials Science And Food Science
by Graham A. WebbA comprehensive collection of the applications of Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI) and Electron-Spin Resonance (ESR). Covers the wide ranging disciplines in which these techniques are used:* Chemistry;* Biological Sciences;* Pharmaceutical Sciences;* Medical uses;* Marine Science;* Materials Science;* Food Science. Illustrates many techniques through the applications described, e.g.:* High resolution solid and liquid state NMR;* Low resolution NMR, especially important in food science;* Solution State NMR, especially important in pharmaceutical sciences;* Magnetic Resonance Imaging, especially important for medical uses;* Electron Spin Resonance, especially important for spin-labelling in food, marine and medical studies.
Modern Management of Abnormal Uterine Bleeding
by Peter Joseph O’Donovan Charles E MillerModern Management of Abnormal Uterine Bleeding focuses on helping gynecologists refine their operative techniques and consider new approaches to the diagnosis, and treatment, of this highly challenging condition by investigating: current scientific and clinical trails &nb
Modern Management of Cancer of the Rectum
by Riccardo A. Audisio Walter E. Longo Vikram ReddyModern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.
Modern Management of Endometriosis
by Kevin Jones G. David Adamson Professor Christopher SuttonEndometriosis - a condition in which the lining of the uterus grows in other abdominal locations - is one of the most common causes of severe period pain, pelvic pain, and abnormal bleeding in women. Untreated, it may result in long-term complications such as pelvic adhesions, ovarian cysts and infertility. At times, bowel, bladder, and ureters may
Modern Management of Uterine Fibroids
by Mostafa Metwally Tin-Chiu LiUterine fibroids are very common in women of reproductive age and are mostly benign. However, they are often a cause of abnormal bleeding and, in severe cases, can cause infertility. This comprehensive guide reviews the clinical management of uterine fibroids, with a particular focus on practical surgical techniques. Engage with topics such as the anatomy of the pelvis, key theatre equipment and surgical treatments including hysteroscopic and laparoscopic techniques. Features also include debates around morcellation, and less invasive treatments such as uterine artery embolisation are also covered. An online video library of surgical procedures reinforces the practical techniques taught in the book and detailed colour images supplement the book's thorough coverage of fibroid management. This makes Modern Management of Uterine Fibroids an essential resource for practicing gynaecologists and IVF specialists, as well as students.
Modern Medicine in New Mexico: The State Medical Society from 1949 to 2009
by Michael Joe DupontSixty years ago, modern medicine finally made its way to New Mexico. As World War II wound down, the state was a quaint backwater filled with aging quacks, Grade C medical graduates, and a vest-pocket professional organization. A group of young-gun doctors and an ex-Marine from Oklahoma changed all that. The state boomed with postwar specialists and patients seeking the sun, and the New Mexico Medical Society (NMMS) quarterbacked the sea changes in state health care. At any number of tipping points--physician shortages, malpractice nightmares, and the crisis of managed care--the state Society played a pivotal role.Based upon archival research and extended interviews with more than fifty past presidents of the NMMS, this volume issued in 2010 describes how the New Mexico Chapter of the American Academy of Family Physicians became a national leader on medical-legal matters, clinical prevention, and continuing education. Rich with anecdotal detail, this work uses the careers of physician-leaders as a prism to present the evolution of state medicine from World War II into the new millennium.
Modern Medicine: Biomedical Devices, Medical Gases, Radiopharmaceuticals, New Drug Discovery, Volume 2
by Pronobesh Chattopadhyay Danswrang GoyaryModern Medicine: Biomedical Devices, Medical Gases, Radiopharmaceuticals, New Drug Discovery, Volume 2 discusses the procedures of drug approval and regulatory requirements that must be met according to the United States Food and Drug Administration (FDA), the European Medical Agency (EMA), and the Central Drug Standard Control Organization (CDSCO). In the rapidly evolving landscape of modern medicine, groundbreaking innovations have emerged that are reshaping the way we approach healthcare. Modern Medicine delves into the cutting-edge realms of medical devices, medical gases, radiopharmaceuticals, and new drug discovery, offering a comprehensive exploration of these transformative fields that are revolutionizing patient care and medical practices. Discover the future of healthcare technology, and uncover the intricate world of biomedical engineering, where state-of-the-art devices seamlessly merge with the human body to monitor, diagnose, and treat ailments Dive deep into the utilization of medical gases for respiratory conditions, pain management, and even novel applications in regenerative medicine Unravel the mysteries of radiopharmaceuticals, a fusion of molecular imaging and therapy that offers unprecedented insights into the inner workings of the human body Embark on a journey through the intricate processes of drug discovery, where groundbreaking research and cutting-edge technologies are yielding therapies that were once deemed impossible Modern Medicine is a must-read for medical professionals, researchers, students, and anyone intrigued by the remarkable intersection of science, technology, and patient well-being. Join us on a journey to the forefront of medical innovation, where the unimaginable becomes reality, and the future of healthcare takes shape before our eyes. The chapter on regulatory implications for the approval process in this book will be the most useful resource for researchers and students, particularly those with backgrounds in pharma, forensic medicine, regulatory affairs, or those who aspire to succeed in drug research. Additionally, the information contained in this volume of the book could be of great interest to researchers working in the pharmaceutical and health industries.
Modern Medicine: Lay Perspectives And Experiences
by Simon J. Williams Michael CalnanDo lay people view modern medicine as a fountain of hope or a font of despair? What are their experiences of modern medical care and technology, and how do their views and experiences differ across different social groups? Combining theoretical insights with a range of qualitative and ethnographic research, this volume examines lay experiences and evaluation of medicines and drugs, chronic illness and life-saving technology, and reproductive technologies. It also considers the growing popularity of complementary therapies as a potential challenge to orthodox medicine.
Modern Menopausal Hormone Treatment: Facts and Myths About Sex Hormones
by Hilde LöfqvistThis unique book is structured to give the reader a comprehensive view to understand the decline of hormones at midlife and the risks and benefits of evidence based hormonal treatments. The difference between bio-identical and synthetic hormones is shown.With this book the author intends to restore the trust of the mostly positive effects of hormone treatment during menopause. In this book effective hormone treatments that may be carried on for years are discussed. Those hormones may even prevent age related diseases (arthralgia, osteoporosis, cardiovascular diseases) if started at the right time frame directly after menopause, known as "window of opportunity". This book fills a gap for medical health providers and can be of benefit for all women searching evidence-based information and answers on hormone menopausal changes and treatments. The book provides the reader with case histories to show how different women are at the menopausal transition, and what the doctor has to consider in the choice of investigation and treatment.
Modern Methods for Epidemiology
by Yu-Kang Tu Darren C. GreenwoodRoutine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper. However, proper understanding of the challenging statistical theory behind those methods remains essential for correct application and interpretation, and rarely seen in the medical literature. Modern Methods for Epidemiology provides a concise introduction to recent development in statistical methodologies for epidemiological and biomedical researchers. Many of these methods have become indispensible tools for researchers working in epidemiology and medicine but are rarely discussed in details by standard textbooks of biostatistics or epidemiology. Contributors of this book are experienced researchers and experts in their respective fields. This textbook provides a solid starting point for those who are new to epidemiology, and for those looking for guidance in more modern statistical approaches to observational epidemiology. Epidemiological and biomedical researchers who wish to overcome the mathematical barrier of applying those methods to their research will find this book an accessible and helpful reference for self-learning and research. This book is also a good source for teaching postgraduate students in medical statistics or epidemiology.
Modern Methods in Carbohydrate Synthesis (Frontiers In Natural Product Research Ser. #Vol. 1)
by Shaheer H. KhanModern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important field of enzymatic synthesis, also covering combined chemical and enzymatic synthesis.Chapters are written by leading experts in the field. Wherever possible, methods of synthesis are provided in sufficient detail to allow the reader to implement the techniques described. More than 1700 references are provided in the 21 chapters comprising the book. This volume should provide a wealth of information to a large number of synthetic organic chemists, medicinal chemists, protein chemists, biochemists, glycobiologists and cell biologists, including students in these fields.
Modern Methods of Pharmaceutical Analysis, Second Edition, Volume II
by Roger E. SchirmerThis book reviews several of the newer methods that find wide application in pharmaceutical analysis, as well as several older methods of unique importance. The principle of each technique is discussed with emphasis on factors that directly affect its proper application to analytical problems .
Modern Microtia Reconstruction: Art, Science, and New Clinical Techniques
by John F. Reinisch Youssef TahiriMicrotia is a rare congenital deformity where the external ear is underdeveloped or absent. Occurring on average in one out of 12,000 children born in the world, there are very few books dedicated to ear reconstruction and microtia, specifically. Microtia reconstruction is a relatively uncommon and notoriously difficult procedure, where hearing as well as external ear deformity need to be addressed. This book is the result of 30 years dedicated to the surgical treatment of microtia: understanding in depth the pathophysiology and trying various surgical techniques to provide long lasting and pleasing aesthetic and functional results. With the limited amount of published information on microtia and ear reconstruction, Modern Microtia Reconstruction shines significant light on the new techniques and advances currently available. It presents advanced surgical techniques alongside inventive approaches that will lay the foundation on which surgeons can continue to expand their knowledge and know-how of the surgical approach of ear reconstruction. While the literature that is currently available on ear reconstruction focuses primarily on cartilage-based surgery, this book explores several other techniques detailing their advantages and disadvantages for both the surgeon and the patient discussing techniques for primary ear reconstruction, secondary ear reconstruction, reconstruction in the unsatisfied patient, as well as for post-traumatic ear reconstruction. Providing not only full-color images and illustrations but extensive video clips of each surgical technique to truly see and experience the subtleties of the surgery in a variety of patients. The primary audience is plastic surgeons, ENT surgeons, oral/maxillofacial surgeons, audiologists, physician’s assistants, and nurse practitioners with a secondary audience of course being highly knowledgeable parents of patients with microtia. With over a quarter of a century experience between the two editors, this book represents a major advance in showing a reliable approach to ear reconstruction surgery
Modern Molecular Biology:
by William B. Isaacs Srinivasan YegnasubramanianMolecular biology has rapidly advanced since the discovery of the basic flow of information in life, from DNA to RNA to proteins. While there are several important and interesting exceptions to this general flow of information, the importance of these biological macromolecules in dictating the phenotypic nature of living creatures in health and disease is paramount. In the last one and a half decades, and particularly after the completion of the Human Genome Project, there has been an explosion of technologies that allow the broad characterization of these macromolecules in physiology, and the perturbations to these macromolecules that occur in diseases such as cancer. In this volume, we will explore the modern approaches used to characterize these macromolecules in an unbiased, systematic way. Such technologies are rapidly advancing our knowledge of the coordinated and complicated changes that occur during carcinogenesis, and are providing vital information that, when correctly interpreted by biostatistical/bioinformatics analyses, can be exploited for the prevention, diagnosis, and treatment of human cancers. The purpose of this volume is to provide an overview of modern molecular biological approaches to unbiased discovery in cancer research. Advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression will be overviewed. These include the strategies employed in modern genomics, gene expression analysis, and proteomics.
Modern Monitoring in Anesthesiology and Perioperative Care
by Andrew B. Leibowitz Suzan UysalClose monitoring of patients during anesthesia is crucial for ensuring positive treatment outcomes and patient safety. The increasing availability of new technologies and the repurposing of older monitors means more patient data is at anesthesiologists' fingertips than ever before. However, this flood of options can be overwhelming. A practical resource for understanding this array of clinical monitoring options in anesthesia, this important text focuses on real-world applications in anesthesia and perioperative care. Reviewing the evidence for improved patient outcomes for monitoring technology, neurological monitoring, echocardiography systems and ultrasound are amongst the techniques covered in a head-to-toe approach. Statistics used by manufacturers to gain approval for their technology are discussed, as well as the under-appreciated risks associated with monitoring such as digital distraction. Future monitoring technologies including wearable systems are explored in depth. Focusing on applied practice, this book is an essential text for front-line healthcare professionals in anesthesia.
Modern Natural Product Synthesis: Overcoming Difficulties
by Masahisa Nakada Keiji Tanino Kazuo Nagasawa Satoshi YokoshimaIn this book, key experts in the field of total synthesis of natural products in Japan describe the details of their synthesis routes including unexpected reactions and syntheses. By presenting detailed stories behind the total synthesis developments, including those routes that were unsuccessful the book provides the reader with a better understanding of how other researchers devise their strategy and overcome difficulties in their studies. The contributions in the book have focused on highlighting the research from Japan however it is appealing to researchers and students worldwide. This compilation of cutting-edge natural product synthesis provides high-quality expertise, especially to graduate students and young researchers, regarding research on synthetic organic chemistry. It can be utilized as teaching material in university seminars as well as provide guidance to researchers in the area of total synthesis.This is an open access book.