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Neurobiological and Psychological Aspects of Brain Recovery (Contemporary Clinical Neuroscience)
by Laura PetrosiniThe importance of this unique book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery following injury. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and psychological resilience the authors present a book that will help lead to the development of better treatment strategies for functional recovery from brain damage. The new edition is fully updated throughout and contains completely new chapters on brain recovery in childhood, epigenetic aspects of brain recovery, and artificial intelligence techniques in traumatic brain injury research.
Neurobiology Essentials for Clinicians: What Every Therapist Needs to Know
by Arlene Montgomery Allan N. SchoreThis book presents an overview of the latest theories of affect regulation and focuses on how these theories work in clinical settings and how therapists can be taught to implement them. The notion of teaching and learning will be extended by the theories themselves-the author presents methods of education that enact the theories being taught. The book is divided into eight chapters, each one highlighting a particular structure or related structures of the brain. Suggestions for learning how to clinically apply the neurobiological/neuroanatomical information are offered. What is so unique about this book is that the bulk of the chapters are clinical dialogue, accompanied by neurobiological commentary. Thus, readers can see for themselves, during the course of parts of sessions, just how a "neurobiological outlook" can inform therapeutic understandings of what clients are doing and saying. The result is a very user-friendly learning experience for readers, as they are taken along a journey of understanding various brain systems and how they relate to psychotherapeutic principles. Elegantly bridging the gap between the academic and clinical domains, this book is essential for anyone interested in the application of neurobiological principles to psychotherapy and wishes to learn about neurobiology without feeling overwhelmed or intimidated.
Neurobiology For Dummies
by Frank Amthor Anne B. TheibertAn essential guide to help you demystify the complex topic of neurobiology and jump into this fascinating scientific field Neurobiology is a notoriously difficult subject, but Neurobiology For Dummies explains the essentials in terms anyone can understand. This fun and accessible book covers the fundamentals, covering the anatomy, physiology, and pathology of the nervous system. Students in fields like neuroscience and pharmacology will get a complete overview of the molecular and cellular mechanisms of the nervous system, making it easier to complete coursework and pass exams in introductory neurobiology courses. In this updated edition, fresh examples highlight the latest research, so you'll be prepared with a current understanding of the science. Whatever your ultimate career destination, this Dummies guide will help you get neurobiology under your belt. Get easy-to-understand explanations of complex topics in neurobiology Understand the latest breakthroughs in neurological disease treatments Learn about the fascinating ways that the brain and body are interconnected Supplement your neurobiology textbook and prepare for your exam This is the perfect resource for students majoring in neuroscience, biology, cognitive science, medicine, and beyond. With Neurobiology For Dummies as a supplement, you can sail through any introductory neurobiology course.
Neurobiology For Dummies
by Frank AmthorThe approachable, comprehensive guide to neurobiology Neurobiology rolls the anatomy, physiology, and pathology of the nervous system into one complex area of study. Neurobiology For Dummies breaks down the specifics of the topic in a fun, easy-to-understand manner. The book is perfect for students in a variety of scientific fields ranging from neuroscience and biology to pharmacology, health science, and more. With a complete overview of the molecular and cellular mechanisms of the nervous system, this complete resource makes short work of the ins and outs of neurobiology so you can understand the details quickly. Dive into this fascinating guide to an even more fascinating subject, which takes a step-by-step approach that naturally builds an understanding of how the nervous system ties into the very essence of human beings, and what that means for those working and studying in the field of neuroscience. The book includes a complete introduction to the subject of neurobiology. Gives you an overview of the human nervous system, along with a discussion of how it's similar to that of other animals Discusses various neurological disorders, such as strokes, Alzheimer's disease, Parkinson's disease, and schizophrenia Leads you through a point-by-point approach to describe the science of perception, including how we think, learn, and remember Neurobiology For Dummies is your key to mastering this complex topic, and will propel you to a greater understanding that can form the basis of your academic and career success.
Neurobiology and Mental Health Clinical Practice: New Directions, New Challenges
by Dennis Miehls and Jeffrey ApplegateThis book illustrates the current findings of interpersonal neurobiology that inform knowledge building and clinical practice. Contributions cover an impressive range of material including how neurobiology interfaces with clinical work with children, individuals with substance abuse issues, couples and clients with trauma histories. Leading mental health clinician-scholars describe path-breaking explorations at the neurobiological frontiers of 21st century clinical theory and practice. Representing the fields of social work, psychology and psychiatry, these authors creatively apply research findings from the ongoing revolution in social and behaviour neuroscience to a diverse array of clinical issues. Contributions include elaborations of theory (the evolving social brain; new directions in attachment, affect regulation and trauma studies); practice (neurobiologically informed work with children, adults, couples and in the conduct of supervision); and emerging neuroscientific perspectives on broader mental health issues and concerns (substance abuse; psychotropic medications; secondary traumatic stress in clinicians; the neurodynamics of racial prejudice; the dangers of forfeiting humanism to our current romance with the biological). Together, these chapters equip readers with state-of-the-art knowledge of the manner in which new understandings of the brain inform and shape today’s professional efforts to heal the troubled mind. This book was originally published as a special issue of Smith College Studies in Social Work.
Neurobiology for Clinical Social Work: Theory and Practice (Norton Series on Interpersonal Neurobiology)
by Jeffrey S. Applegate Janet R. ShapiroThe last fifteen years have produced an explosion of research on the neurobiology of attachment. This research, which explores the ways in which affect regulation play key roles in determining the structure and function of the developing brain and mind, has led to a revolution in the way that parent-child relationships are viewed. Although these insights have informed psychiatry as well as cognitive and psychoanalytic psychology, their application to social work practice, education, and research has been lacking. Here for the first time ever, social work educators Jeffrey Applegate and Janet Shapiro demystify neurobiology and present it anew with the social work audience specifically in mind. Social workers, by virtue of their work with at-risk children and families, occupy a unique position from which to employ this new research in prevention and intervention. This lack of education about neurobiology has unfortunately fostered misconceptions among social workers that these theories are too academic and thus irrelevant to clinical practice. Neurobiology for Clinical Social Work corrects this misconception and introduces social workers to the powerful and practical ideas that are coming out of neurobiological research. The research summarized here offers new insights about the crucial role that relationships play in human development and in professional helping efforts. To set the stage for this inquiry, the authors introduce fundamentals of brain structure, development, and functioning in the first parts of the book. This introduction is intended as a primer and proceeds from the assumption that many readers are relatively unfamiliar with the field of brain science. Building on this foundation, the authors go on to describe the manner in which memory and affect regulation are neuropsychological processes. The next chapters of the book delve into the concepts of attachment. Specifically, the authors are concerned with how precursors to attachment evolve during the earliest months of an infant's life and how various attachment classifications (secure, insecure, disorganized) lead to affect regulation--the ability of a child to regulate emotion. Throughout the book these concepts are discussed in the context of what social workers face when trying to find explanatory structures for the ways in which early childhood experiences affect later life. Later chapters turn even more directly toward practice. Using case examples--including adolescent parents and their children, children with a depressed parent, and children of substance abusing parents--Applegate and Shapiro show clinicians how to make use of neurobiological concepts in designing treatment plans and interventions. One chapter contains three extended case examples, with commentary, representing the three most common intervention models taught in schools of social work--psychodynamic, cognitive-behavioral, and systemic. Various settings, such as community mental health, family service agencies, and child welfare, are also discussed. In order to be effective and meet the complex challenges of the twenty-first century, social work professionals must join with their colleagues in other disciplines in coordinated efforts to integrate and apply newly emerging knowledge toward the enhancement of human well-being. Neurobiology for Clinical Social Work is a great place to start this process of integration and learning.
Neurobiology of Actin
by Gianluca Gallo Lorene M LanierThis text is an introduction to the interface between the actin cytoskeleton and the myriad of issues fundamental to the understanding of the nervous system. It covers the neurobiology of actin ranging from basic cellular organization and function to the roles of actin in the health and disease states of the nervous system. Its opening chapter presents the fundamental concepts required to appreciate the details of the molecular machinery that regulates actin in a cellular context, setting the stage for the first part of the book which reviews the neurobiology of actin at the cellular level. The latter section of the book then discusses the functions of actin in the context of neurobiological issues ranging from early development to synaptic function and disease states of the nervous system. This text is intended for neuroscientists interested in investigating the actin cytoskeleton in the context of their particular neuroscience research program, and its chapters are cross-referenced in order to assist readers in finding relevant information that is covered in greater depth in other chapters.
Neurobiology of Aggression and Rage
by Allan SiegelWhile other books concentrate on the different facets of aggression, these publications tend to focus on a single aspect of the subject and do not make any attempt to integrate biology and behavior. This lack of integration in the literature has created a major gap in our current understanding of the factors that influence aggressive actions. <
Neurobiology of Alzheimer's Disease (Current Topics in Behavioral Neurosciences #69)
by Emma J. Kidd Paul A. NewhouseThis volume brings together pre-clinical and clinical research on topics highly relevant to the development and improvement of our understanding of Alzheimer’s disease (AD). The combination of both research areas will appeal to a broad range of researchers from basic scientists to neurologists. The topics cover both established and more recent areas of research on the underlying causes of this disease which are still not fully understood more than 100 years after its first description by Alois Alzheimer. This broad perspective demonstrates how research into AD is evolving along with considering clinical aspects of the disease. The chosen contributors are well-placed to provide expert views on these topics. The book is divided into 2 sections, pre-clinical research and clinical research. While each section contains unique topics, there are also topics common to both areas such as Down Syndrome, considerations of diversity and behavioural and neurobiological symptoms of dementia to provide a wider perspective on these topics. The inclusion of Down Syndrome demonstrates the reverse translation of knowledge from the clinic to laboratory-based neurobiology. The two main sections are then further subdivided into groups for related topics. The broad overview of this book will encourage researchers to pursue bold and innovative research to expand knowledge of this complex neurodegenerative disease and to improve its detection, diagnosis, treatment, and management.
Neurobiology of Autism Spectrum Disorders
by Abdeslem El Idrissi Dan McCloskeyThis book brings together the exciting new findings that will bring us closer to a better understanding of the alterations of neuronal connectivity in autistic brains. This volume authoritatively covers the epidemiology, physiology, neurodevelopment, genetics, environmental influences, imaging studies, neuroanatomy, and neurochemistry of autism spectrum disorders. While the neurobiology of autism is still a long way from being understood, this book posits techniques, such as using brain imaging to find signatures in early days of life, that could help move the diagnosis and help identify neural pathways. Understanding these mechanisms opens the possibility to pharmacological, behavioral, and psychosocial therapeutic interventions. With contributions from the leading international autism researchers, Neurobiology of Autism Spectrum Disorders is the go-to reference for researchers and clinicians with an interest in understanding the underlying neurobiology of autism spectrum disorders.
Neurobiology of Body Fluid Homeostasis: Transduction and Integration
by Alan Kim Johnson Laurival Antonio De Luca José Vanderlei MenaniA timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, Sao Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad inte
Neurobiology of Cancer: Role of the Nervous System in Cancer Etiopathogenesis, Treatment, and Prevention
by Boris MravecThe focus of this book is to describe the current understanding of the interactions between the nervous system and cancer and the use of this information in the treatment and prevention of cancer. Author and noted researcher Boris Mravec presents a clearly written and well-illustrated monograph on this rapidly developing new field. The book begins with an exploration of the basic concepts supporting the neurobiology of cancer, discusses the ways in which the nervous system affects all the hallmarks of cancer, delves extensively into stress and cancer, covers the etiopathogenetic consequences of the neurobiology of cancer, the implications for cancer prevention and treatment, and looks at future directions in the field.
Neurobiology of Chemical Communication (Frontiers in Neuroscience)
by Carla Mucignat-CarettaIntraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism-ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their prese
Neurobiology of Depression (Frontiers in Neuroscience)
by Cecilio Álamo Francisco López-MunozMajor depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, mol
Neurobiology of Grooming Behavior
by Allan V. Kalueff Justin L. Laporte Carisa L. BergnerGrooming is among the most evolutionary ancient and highly represented behaviours in many animal species. It represents a significant proportion of an animal's total activity and between 30-50% of their waking hours. Recent research has demonstrated that grooming is regulated by specific brain circuits and is sensitive to stress, as well as to pharmacologic compounds and genetic manipulation, making it ideal for modelling affective disorders that arise as a function of stressful environments, such as stress and post-traumatic stress disorder. Over a series of 12 chapters that introduce and explicate the field of grooming research and its significance for the human and animal brain, this book covers the breadth of grooming animal models while simultaneously providing sufficient depth in introducing the concepts and translational approaches to grooming research. Written primarily for graduates and researchers within the neuroscientific community.
Neurobiology of Huntington's Disease: Applications to Drug Discovery (Frontiers in Neuroscience)
by Donald C. Lo Robert E. HughesIn 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that see
Neurobiology of Interval Timing
by Hugo Merchant Victor De LafuenteThe study of how the brain processes temporal information is becoming one of the most important topics in systems, cellular, computational, and cognitive neuroscience, as well as in the physiological bases of music and language. During the last and current decade, interval timing has been intensively studied in humans and animals using increasingly sophisticated methodological approaches. The present book will bring together the latest information gathered from this exciting area of research, putting special emphasis on the neural underpinnings of time processing in behaving human and non-human primates. Thus, Neurobiology of Interval Timing will integrate for the first time the current knowledge of both animal behavior and human cognition of the passage of time in different behavioral context, including the perception and production of time intervals, as well as rhythmic activities, using different experimental and theoretical frameworks. The book will the composed of chapters written by the leading experts in the fields of psychophysics, functional imaging, system neurophysiology, and musicology. This cutting-edge scientific work will integrate the current knowledge of the neurobiology of timing behavior putting in perspective the current hypothesis of how the brain quantifies the passage of time across a wide variety of critical behaviors.
Neurobiology of Motor Control: Fundamental Concepts and New Directions
by Ansgar Büschges Scott L. HooperA multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.
Neurobiology of Respiration
by Mieczyslaw PokorskiRespiration is an area of the medical study that undergoes fast developments. A better understanding of the neural and cellular mechanisms underlying respiratory disorders and lung function is essential for the evidence-based pharmacotherapy and for optimizing the patient care and prophylactic measures to improve the health and quality of life. This comprehensive book is a blend of basic and clinical research. The book is thought to promote the translation of science into clinical practice. The book presents an update on the areas of current research and clinical interest in the neurobiology of the respiratory system. Recent innovations in detection and management of respiratory diseases are described. The book will be a base of reference in the field of respiration for years to come and a source of future research ideas. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for 'bench to bedside' treatments of lung diseases.
Neurobiology of Sensation and Reward
by Jay A. GottfriedSynthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a
Neurobiology: A Functional Approach
by Georg F. StriedterFocusing on the problems that brains help organisms solve, Neurobiology: A Functional Approach asks not only how the nervous system works but also why it works as it does. This text introduces readers to neurobiology through an evolutionary, organismal, and experimental perspective. With a strong emphasis on neural circuits and systems, it bridges the gap between the cellular and molecular end and the cognitive end of the neuroscience spectrum, allowing students to grasp the full breadth of the subject. Neurobiology covers not only what neuroscientists have learned about the brain in terms of facts and ideas, but also how they have learned it through key experiments.
Neurobiology: Methods and Protocols (Methods in Molecular Biology #2746)
by Sebastian DworkinThis volume will serve as a guide for students in the field of neurobiology, and be a bridge between basic science researchers, doctors, and surgeons in clinical practice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Neurobiology: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Neurobiopsychosocial Perspectives on Aggression and Violence: From Biology to Law Enforcement (Advances in Preventing and Treating Violence and Aggression)
by József HallerThis book bridges the gap between basic science, which deals with general concepts of aggression and its neurobiological foundations, and law enforcement as one of the applied fields of aggression research. It addresses the current state of research and practice and compares and integrates the concept of aggression with violent crime. Chapters examine the types of criminal careers that cross the boundary between the two and summarize the biological, psychological, and social factors that underlie particular types of criminal careers. Subsequent chapters discuss overlaps between biological and psychological factors and detail how and to what extent aggression may serve as explanatory mechanisms for violence. The book also discusses the relationship between social problems and neuropsychological deficits, addressing how the neuropsychological deficits lead to the intergenerational recycling of social problems. Finally, the volume explores violence and aggression from a neurobiological perspective. Topics featured in this book include:The heritability of aggressiveness and violence-proneness.Glucocorticoids in humans.Aggression circuitry in animals.Distorted circuitry in violent animals.Biological factors of psychological change. Neurobiopsychosocial Perspectives on Aggression and Violence is a must-have resource for researchers, clinicians and other professionals, and graduate students in forensic psychology, criminology/criminal justice, public health, developmental psychology, psychotherapy/counseling, psychiatry, social work, educational policy and politics, health psychology, nursing, and behavioral therapy/rehabilitation.
Neuroblastoma
by M. A. HayatIntroduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
Neuroblastoma: Clinical and Surgical Management
by Sabine Sarnacki Luca PioThis book addresses neuroblastoma, a type of embryonic tumor derived from neural crest cells and one of the most frequent extra-cranial solid tumors in children. However, the term also describes a heterogeneous group of tumors, the prognosis of which can differ greatly according to age, stage and biology. Some forms undergo spontaneous regression, and some are cured by surgery alone or after chemo-reduction, while others exhibit extremely aggressive behavior. Their successful treatment is one of the best examples of tailored medicine, which involves close collaboration between pediatric surgeons, pediatric oncologists, radiologists, nuclear medicine specialists, biologists, oncogeneticists and radiotherapists. The book pursues a unique approach, as it combines most essential insights from all of these fields, together with key information regarding epidemiology, physiopathology and palliative care. The respective chapters were written by the leading international experts on neuroblastoma, and present the latest advances in terms of research, surgical approaches and medical treatments. The book offers an invaluable resource to all pediatric surgeons, pediatricians, oncologists, students, researchers and all others involved in neuroblastoma management who want to benefit from their colleagues’ expertise.