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Nobody's Normal: How Culture Created The Stigma Of Mental Illness
by Roy Richard GrinkerA compassionate and captivating examination of evolving attitudes toward mental illness throughout history and the fight to end the stigma. For centuries, scientists and society cast moral judgments on anyone deemed mentally ill, confining many to asylums. In Nobody’s Normal, anthropologist Roy Richard Grinker chronicles the progress and setbacks in the struggle against mental-illness stigma—from the eighteenth century, through America’s major wars, and into today’s high-tech economy. Nobody’s Normal argues that stigma is a social process that can be explained through cultural history, a process that began the moment we defined mental illness, that we learn from within our communities, and that we ultimately have the power to change. Though the legacies of shame and secrecy are still with us today, Grinker writes that we are at the cusp of ending the marginalization of the mentally ill. In the twenty-first century, mental illnesses are fast becoming a more accepted and visible part of human diversity. Grinker infuses the book with the personal history of his family’s four generations of involvement in psychiatry, including his grandfather’s analysis with Sigmund Freud, his own daughter’s experience with autism, and culminating in his research on neurodiversity. Drawing on cutting-edge science, historical archives, and cross-cultural research in Africa and Asia, Grinker takes readers on an international journey to discover the origins of, and variances in, our cultural response to neurodiversity. Urgent, eye-opening, and ultimately hopeful, Nobody’s Normal explains how we are transforming mental illness and offers a path to end the shadow of stigma.
Nocturia
by Jeffrey P. Weiss, MD, FACS Philip E. Van Kerrebroeck, MD, PhD, MMSc Jerry G. Blaivas Facs, Phd Hon Alan J. Md, Facs, Phd Hon Alan J. WeinNocturia: Causes, Consequences and Clinical Approaches is the first volume exclusively on the topic of nocturia and is designed to be a comprehensive treatise on the subject. The volume is organized into 11 chapters first introducing and defining nocturia and its impact to patients and society, followed by chapters dealing with predictors and risk factors; relationship to sleep disorders; overactive bladder; and water homeostasis. Therapeutic areas addressing nocturia are covered in specific chapters and include pharmacotherapy affecting the bladder, prostate and kidneys as well as behavioral therapy and surgical intervention. Separate chapters are devoted to alternative therapies as well as the impact of nocturia in the elderly. The volume closes with a chapter presenting avenues for future investigation into the etiology and management of nocturia. Clinical case scenarios inclusive of figures and tables illuminate the evaluation and management of patients with nocturia. Nocturia: Causes, Consequences and Clinical Approaches will give physicians and related healthcare providers the background to understand the conditions causing nocturia, how nocturia affects society and the basis for its rational treatment. It will be used as a state of the art reference by urologists, urogynecologists, internists, nephrologists, pulmonologists, endocrinologists and sleep medicine specialists.
Nocturnal Non-Invasive Ventilation
by Robert C. Basner Sairam ParthasarathyThis comprehensive resource brings together the most current theories, evidence and best practice parameters for the use of nocturnal non-invasive ventilation (nNIV). Chapters focus on the application of acute and chronic nNIV in patients with cardio-respiratory disorders over a range of major medical settings. Updates on past and recent research in this field are highlighted. Authored by leading clinicians and investigators, Nocturnal Non-Invasive Ventilation provides practical and cutting-edge knowledge to physicians, researchers and allied health professionals on the front lines of treating cardio-respiratory and sleep disorders.
Nog lang en gelukkig
by Allan ChinonSprookjes zijn eigenlijk gelijkenissen waarin de reis van de mens door het leven wordt uitgebeeld. De meeste sprookjes eindigen met de jeugdige droom van geluk, maar het werkelijke leven eindigt natuurlijk niet met jeugd of eeuwige gelukzaligheid. Ouderdomssprookjes symboliseren de ontwikkelingstaken die de mens moet volbrengen in de tweede levenshelft. Ze gaan over oud worden, maar ook over groei. Ze geven een visie op wat het leven op middelbare en latere leeftijd kan inhouden.
Noise Pollution and Ergonomic Intervention by Acoustic Material (Synthesis Lectures on Mechanical Engineering)
by Noe Alba-Baena Suchismita Satapathy Meghana Mishra Tushar Kanta MahapatraThis book is based on the understanding as well as the use of information technology extensively, to explore OHS related risk in major risky sectors due to noise and a framework is suggested through the systematic analysis of the barriers and its implementations. Ergonomic analysis is done to investigate problems associated with hearing. Acoustic materials are fabricated and tested. A case study is conducted to reduce noise by placing accoustic material.
Noise and Randomness in Living System
by Sisir Roy Sarangam MajumdarThis book illustrates the role of randomness and noise in living organisms. Traditionally, the randomness and noise have been used in understanding signal processing in communications. This book is divided into two sections, the first of which introduces readers to the various types and sources of noise and the constructive role of noise in non-linear dynamics. It also analyses the importance of randomness and noise in a variety of science and engineering applications. In turn, the second section discusses in detail the functional role of noise in biological processes for example, in case of brain function at the level of ion channel, synaptic level and even at cognitive level. These are described in various chapters. One of the challenging issue finding the neuronal correlates of various meditative states is to understand how brain controls various types of noise so as to reach a state of synchronized oscillatory state of the brain corresponding to the state of Samadhi. This is described in details in one chapter called Noise, Coherence and meditation. The concept of noise and the role of randomness in living organism raise lot of controversy for last few decades. This is discussed in a separate chapter. Finally, the epistemic and ontic nature of randomness as discussed in physical science are investigated in the context of living organism.
Noise-Induced Hearing Loss
by Arthur N. Popper Richard R. Fay Donald Henderson Colleen G. Le PrellExposure to loud noise continues to be the largest cause of hearing loss in the adult population. The problem of NIHL impacts a number of disciplines. US standards for permissible noise exposure were originally published in 1968 and remain largely unchanged today. Indeed, permissible noise exposure for US personnel is significantly greater than that allowed in numerous other countries, including for example, Canada, China, Brazil, Mexico, and the European Union. However, there have been a number of discoveries and advances that have increased our understanding of the mechanisms of NIHL. These advances have the potential to impact how NIHL can be prevented and how our noise standards can be made more appropriate.
Nolo's Guide to Social Security Disability: Getting & Keeping Your Benefits
by David A. Morton IIINolo's Guide to Social Security Disability covers the criteria for getting disability benefits for back problems, heart and cardiovascular disease, diabetes, cancer, autoimmune diseases, mental issues like depression and anxiety, and 200 more medical conditions. Learn how to match the medical details of your disability to Social Security regulations to make sure you have the right evidence to qualify for the benefits you're due when you apply. This guide is written by a former Chief Medical Consultant for the Social Security Administration whose expert deciphering of the medical portions of SSA regulations will help you understand how you can get benefits. If you've been denied benefits already, this book will tell you how to find out why and what steps to take to prove that you should get benefits on appeal. This edition is completely updated with the latest rules and information plus updated figures for 2018 and many updated medical listings.
Nolo's Guide to Social Security Disability: Getting & Keeping Your Benefits
by David A. Morton IIIQualify for Social Security disability benefits, quickly and easily Nolo's Guide to Social Security Disability covers the criteria for getting disability benefits for back problems, heart and cardiovascular disease, diabetes, cancer, autoimmune diseases, mental issues like depression and anxiety, and 200 other medical conditions. Learn how to match the medical details of your disability to Social Security regulations to make sure you have the right evidence to qualify for the benefits you're due when you apply. This guide is written by a former Chief Medical Consultant for the Social Security Administration whose expert deciphering of the medical portions of SSA regulations will help you understand how you can get benefits. If you’ve been denied benefits already, this book will tell you how to find out why and what steps to take to prove that you should get benefits on appeal. This edition is completely updated with the latest rules and information plus updated figures for 2020 and many updated medical listings.
Nolph and Gokal's Textbook of Peritoneal Dialysis
by Raymond T. Krediet Ramesh KhannaNolph and Gokal's Text Book of Peritoneal Dialysis, Third Edition, covers advances made in the field for the past 30 years. During the past two decades, the time during which this therapy has been increasingly utilized, this text has continued to be recognized as the major source of the discipline's base knowledge. The evolution of this text to its newest edition parallels the growth of peritoneal dialysis from Continuous Ambulatory Peritoneal Dialysis in the eighties to the current therapy that encompasses manual and automated therapies with full emphasis on adequacy of dialysis dose. Peritoneal dialysis represents an intracorporeal technique for blood purification. This unique dialysis system represents one of many human attempts to manipulate nature for sustenance of life. The past few years of advances have focused on further improvement of the technique. Areas that have fueled the interest of researchers include: (1) Physiology of high transporters (and the role of genetics and inflammation); (2) Continued debate over the most appropriate adequacy indices (small solute clearances, large solute clearances, clinical assessment etc.); (3) Understanding, preventing and treating the MIA syndrome in PD patients ( including the roles of leptin, and adiponectin); (4) Pathogenesis and newer management strategies of vascular calcification; (5) Continued improvements in infectious complications including peritonitis; (6) Further improvements in catheter technology; (7) Automated techniques; (8) Explaining and correcting PD underutilization; (9) Rationale and applications of newer dialysis solutions; (10) New understanding and approaches to management of osteodystrophy; (11) Refinements in anemia management including new insights in iron metabolism in PD patients; (12) Further definition of indications for PD; (13) The ideal time to initiate dialysis. Newer insight into host defense mechanisms have also made the past decade of advances in the field more meaningful for clinicians. This text also covers the knowledge gained from animal models of peritoneal dialysis. Nolph and Gokal's Textbook of Peritoneal Dialysis, Third Edition is a compilation of the latest knowledge in the field. It cites and describes in great detail, the new discoveries and the evolution of understanding the subject of these discoveries.
Nolph and Gokal's Textbook of Peritoneal Dialysis
by Raymond T. Krediet Ramesh KhannaThis fourth edition comprehensively covers peritoneal dialysis. Peritoneal dialysis represents an intracorporeal technique for blood purification. This unique dialysis system represents one of many human attempts to manipulate nature for sustenance of life. Recent advances have focused on further improvement of the technique, which are covered in full throughout the text. During the past decade, the time during which this therapy has been increasingly utilized, the 3rd Edition has continued to be recognized as the major source of the discipline's base knowledge. The evolution of this text to its newest edition parallels the growth of peritoneal dialysis from Continuous Ambulatory Peritoneal Dialysis in the eighties to the current therapy that encompasses manual and automated therapies with full emphasis on adequacy of dialysis dose. Nolph and Gokal's Textbook of Peritoneal Dialysis is the most in-depth publication on this dialysis technique and is an ideal resource for all clinicians practicing peritoneal dialysis.
Non B cell-Derived Immunoglobulins: The Structure, Characteristics and the Implication on Clinical Medicine (Advances in Experimental Medicine and Biology #1445)
by Jing Huang Xiaoyan Qiu Xiaojun XuThis book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.
Non Coding RNAs in Plants
by Jan Barciszewski Volker A. ErdmannIn the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biological activities and specific functional scopes. RNA silencing plays a crucial role in coordinating the expression, stability, protection and inheritance of eukaryotic genomes. It compromises several mechanisms, that invariably depend on core small non coding RNAs and that achieve dedicated sequence-specific functions. RNA silencing has been recognized to carry critical developmental, stress-response and bodyguard functions be coordinating the expression, protection, stability and inheritance of virtually all eukaryotic genomes. Thus, the ncRNAs encompass a wide set of mechanisms that achieve specialized functions.
Non Invasive Artificial Ventilation
by Stefano Nava Francesco FanfullaOver the last two decades, the increasing use of noninvasive ventilation (NIV) has reduced the need for endotracheal ventilation, thus decreasing the rate of ventilation-induced complications. Thus, NIV has decreased both intubation rates and mortality rates in specific subsets of patients with acute respiratory failure (for example, patients with hypercapnia, cardiogenic pulmonary edema, immune deficiencies, or post-transplantation acute respiratory failure). Despite the increased use of NIV in clinical practice, there is still a need for more educational tools to improve clinicians' knowledge of the indications and contraindications for NIV, the factors that predict failure or success, and also what should be considered when starting NIV. This book has the dual function of being a "classical" text where the major findings in the literature are discussed and highlighted, as well as a practical manual on the tricks and pitfalls to consider in NIV application by both beginners and experts. For example, setting the ventilatory parameters; choosing the interfaces, circuits, and humidification systems; monitoring; and the "right" environment for the "right" patient will be discussed to help clinicians in their choices.
Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences
by Bernardo Dell’Osso Giorgio Di LorenzoThis book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.
Non Invasive Diagnostic Techniques in Clinical Dermatology
by Howard I. Maibach Enzo Berardesca Klaus-Peter WilhelmThis book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration and erythema and blood flow. All of the authors are experts in the field, with detailed knowledge of the techniques they describe. Non Invasive Diagnostic Techniques in Clinical Dermatology will be of value for all dermatologists, whether they are engaged in delivering patient care or in research programs, for cosmetic scientists and for biologists involved in skin research and product assessment.
Non-Alcoholic Fatty Liver Disease
by Geoffrey C. Farrell Christopher P. Day Arthur J. McculloughThe sharp rise in cases of Non-alcoholic fatty liver disease is fast becoming one of the major concerns for hepatologists worldwide. This comprehensive clinical guide explains how to diagnose NAFLD and manage patients according to the best standards of care. Contributors from the world's leading institutions concentrate on patient care, drawing on their extensive experience.
Non-Alcoholic Fatty Liver Disease: A 360-degree Overview
by Elisabetta BugianesiThe goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the latest scientific understanding of this multisystemic disease, involving the expertise of specialists including hepatologists, diabetologists, and cardiologists. The respective contributions address various aspects, including the newly released international guidelines, novel diagnostic modalities, and new experimental drugs. The work will appeal to a broad readership, from residents in internal medicine to specialists.
Non-Alcoholic Steatohepatitis: Methods and Protocols (Methods in Molecular Biology #2455)
by Devanand SarkarThis volume contains a comprehensive collection of laboratory protocols used by researchers to analyze varied aspects of non-alcoholic steatohepatitis (NASH). The chapters in this book cover topics such as methods for histological diagnosis of NASH; the purpose of generating an in vivo NASH model; protocols for isolating hepatocytes and Kupffer cells, bone marrow derived macrophages, and adipocytes; techniques to develop human pluripotent stem cells-derived liver organoids; single-cell and RNA-sequencing; and a description of how to extract exosomes and exosomal miRNAs from mesenchymal stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Non-Alcoholic Steatohepatitis: Methods and Protocols is a valuable resource for new and experiences investigators studying NASH, and serves as an essential reference on NASH for basic and clinical researchers and students.
Non-Aligned Psychiatry in the Cold War: Revolution, Emancipation and Re-Imagining the Human Psyche (Mental Health in Historical Perspective)
by Ana AntićThis book explores the relationship between socialist psychiatry and political ideology during the Cold War, tracing Yugoslav ‘psy’ sciences as they experienced multiple internationalisations and globalisations in the post-WWII period. These unique transnational connections – with West, East and South – remain at the centre of this book. The author argues that the ‘psy’ disciplines provide a window onto the complications of Cold War internationalism, offering an opportunity to re-think postwar Europe's internal dynamics. She tells an alternative, pan-European narrative of the post-1945 period, demonstrating that, in the Cold War, there existed sites of collaboration and vigorous exchange between the two ideologically opposed camps, and places like Yugoslavia provided a meeting point, where ideas, frameworks and professional and cultural networks from both sides of the Iron Curtain could overlap and transform each other. Moreover, the book offers the first analysis of East European psychiatrists’ contacts with and contributions to the decolonizing world, exploring their participation in broader political discussions about decolonization, anti-imperialism and non-alignment. The Yugoslav brand of East-West psychoanalysis and psychotherapy bred a truly unique intellectual framework, which enabled psychiatrists to think through a set of political and ideological dilemmas regarding the relationship between individuals and social structures. This book offers a thorough reinterpretation of the notion of ‘communist psychiatry’ as a tool used solely for political oppression, and instead emphasises the political interventions of East European psychiatry and psychoanalysis.
Non-Alzheimer's and Atypical Dementia
by Michael D. Geschwind Caroline Racine BelkouraDementia is the most common type of neurodegenerative disorder. Non-Alzheimer's and Atypical Dementia concentrates on each form of dementia individually, considering symptoms, diagnosis and treatment Focuses on non-Atypical Dementia Multidisciplinary approach to diagnosis and management Allows development of management and care plan strategies Practical approach including case studies Written by a world-renowned editorial team
Non-Biological Complex Drugs
by Daan J.A. Crommelin Jon S. B. de VliegerThe rise of bio- and nano-technology in the last decades has led to the emergence of a new and unique type of medicine known as non-biological complex drugs (NBCDs). This book illustrates the challenges associated with NBCD development, as well as the complexity of assessing the effects of manufacturing changes on innovator and follow-on batches of NBCDs. It also touches upon proven marketing authorization requirements for biosimilars that could be effective in evaluating follow-on NBCDs, including a demonstration of control over the manufacturing process and a need for detailed physico-chemical characterization and (pre)clinical tests. This book is meant to be used for years to come as a standard reference work for the development of NBCDs. Moreover, this book aims to stimulate discussions and further our thinking to ensure that decisions regarding the approval of complex drugs are made with relevant scientific data on the table.
Non-Clinical Vascular Infusion Technology, Volume I: The Science
by Owen P. Green Guy HealingIntravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. For the first time, th
Non-Clinical Vascular Infusion Technology, Volume II: The Techniques
by Owen P. Green and Guy HealingIntravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. With contributions fro
Non-Heart-Beating Organ Transplantation: Medical and Ethical Issues in Procurement
by Roger HerdmanNon-heart-beating donors (individuals whose deaths are determined by cessation of heart and respiratory function rather than loss of whole brain function) could potentially be of major importance in reducing the gap between the demand for and available supply of organs for transplantation. Prompted by questions concerning the medical management of such donors--specifically, whether interventions undertaken to enhance the supply and quality of potentially transplantable organs (i.e. the use of anticoagulants and vasodilators) were in the best interests of the donor patient--the U.S. Department of Health and Human Services asked the Institute of Medicine to examine from scientific and ethical points of view "alternative medical approaches that can be used to maximize the availability of organs from [a] donor [in an end-of-life situation] without violating prevailing ethical norms...."This book examines transplantation supply and demand, historical and modern conceptions of non-heart-beating donors, and organ procurement organizations and transplant program policies, and contains recommendations concerning the principles and ethical issues surrounding the topic.