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Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke
by John H. Zhang Jun Chen Xiaoming HuThis book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.
Non-Obstetric Surgery During Pregnancy
by Ceana H. Nezhat Michael S. Kavic Raymond J. Lanzafame Michael K. Lindsay Travis M. PolkAs minimally invasive surgical techniques evolve, the outlook for patients continues to brighten. This is also true for pregnant women experiencing conditions requiring surgical intervention during gestation. A physician’s ability to identify potential risk factors in pregnant patients that present pre-op directly corresponds with their success in monitoring patients in post-op for adverse obstetric outcomes from non-obstetric surgeries. The utilization of laparoscopic techniques during surgery for pregnant patients has decreased the risk of fetal complications and increased the positive outlook for the duration of the pregnancy. This text is designed to present a minimally invasive approach to surgery that is non-obstetrics related and to educate readers on the potential risk factors and negative outcomes on pregnant patients following non-obstetric surgery. The various sections of this book will address issues faced by surgeons who undertake the task of operating on the pregnant patient. When performing non-obstetric surgery on a pregnant patient the ability to identify possible risk factors for adverse obstetric outcomes is important. Risk factors can be maternal-, surgical-, obstetrical-, or disease-associated. Common adverse obstetric outcomes following non-obstetric surgery include preterm delivery, preterm labor without preterm delivery, and miscarriage. Fetal well-being is an additional risk-benefit factor to be considered when weighing options before conducting non-obstetric surgeries on pregnant patients. This book will provide physicians with the knowledge and tools to identify common risk factors and successfully apply evidence-based risk reduction. To date, no comprehensive resource is available for non-obstetric surgery during pregnancy. Types of pregnancies, potential complications, proper use of anesthesia, types of risk factors (maternal-, surgical-, obstetrical-, and disease-associated), etc. will be thoroughly explained and depicted within these pages. All chapters will be written by subject matter experts in their fields. All information communicated will be comprised of the most currently available knowledge
Non-Operative Treatment of the Lumbar Spine
by Grant CooperBridging the gap between the medical literature and the practice of lumbar spine medicine, this user-friendly, accessible text describes the causes of lower back pain and associated "sciatic" pathologies and how these problems can be successfully treated without surgery. Beginning with a review of the anatomy of the lumbar spine and the most common causes of lower back pain, diagnostic and management strategies for a variety of conditions are discussed, including discogenic pain, facet joint pain, sacroiliac joint pain, spondylolisthesis, lumbar radiculopathy, piriformis syndrome, spinal stenosis, and compression fractures. Chapters on epidural steroid injections, exercises for lower back pain and alternative treatments follow, as well as when it is appropriate to recommend surgery. The second section of the book is devoted to numerous clinical scenarios in which evidence based medicine is applied to actual clinical cases. Non-Operative Treatment of the Lumbar Spine will be a valuable reference for orthopedists, rheumatologists, physiatrists, pain management specialists, neurologists, and anyone treating patients with lower back pain.
Non-Parkinsonian Movement Disorders
by Brandon R. Barton Deborah A. HallA clinical ‘in the office’ or ‘at the bedside’ guide to effective patient care for neurologists in practice and in training Each presentation includes practical descriptions of phenomenology, and key clinical information from the history and neurological examination that guide the physician to the correct diagnosis, and treatment options Throughout the book Science Revisited highlights remind clinicians of the scientific anchors related to each disorder, and Evidence at a Glance boxes summarise clinical trial evidence-based review information Numerous video clips in every chapter demonstrate different movement disorders to aid diagnosis Unique learning tools, Tips and Tricks and Caution Warning boxes, give useful hints on improving outcomes and preventing errors
Non-Pharmacological Interventions: An Essential Answer to Current Demographic, Health, and Environmental Transitions
by Gregory NinotNon-pharmacological interventions (NPIs) have become essential solutions for better living, preventing disease, and self-care, in addition to biomedical treatments, and for increasing longevity without loss of quality of life. Over the past 20 years, these practices have gone from general diet and hygiene advice to targeted and personalized solutions for prevention, care optimization, and curative treatments. Selected empirically for centuries or recently with the help of technological innovations and epigenetic, interventional, and medico-economic studies, their development is growing and diversifying around the world. Today an NPI ecosystem is made up of a myriad of public and private actors. As interest in NPIs grows, so do questions about safety, effectiveness, standardization, ethical practice, and surveillance. In this book, the author answers these questions with a scientific approach, because evidence-based science, evidence-based practice, clinical research, and data monitoring have revolutionized this field. Topics explored among the chapters include: · Defining Non-Pharmacological Interventions · The Benefits and Dangers of Non-Pharmacological Interventions · Motives and Facilitators of Non-Pharmacological Intervention Use · The Market for Non-Pharmacological Interventions · Evaluation of Non-Pharmacological Interventions · The Future of Non-Pharmacological Interventions Non-Pharmacological Interventions: An Essential Answer to Current Demographic, Health, and Environmental Transitions is a must-have resource for clinicians and other health professionals, researchers, students, health insurers, policy-makers, caregivers, and entrepreneurs in the health and wellness space, as well as any users who wish to inform themselves about NPIs.
Non-Pulmonary Complications of Critical Care
by Jeremy B. Richards Renee D. StapletonClinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic administration and sedation and analgesia. However, despite improved clinical care, many critically ill patients continue to experience complications of critical illness - some complications are iatrogenic and preventable, while others are simply a component of the natural history of critical illness. These complications lead to increased mortality, morbidity, cost and long-term chronic conditions. Non-Pulmonary Complications of Critical Care: A Clinical Guide is a valuable resource for trainees and clinicians who aim to better understand and improve the quality of critical care medicine. Armed with information about potential non-pulmonary complications of ICU care and strategies to minimize or prevent those complications, the critical care clinician will be able to help ICU patients potentially avoid much of the morbidity associated with critical illness. This book is organized by organ system such that it can be easily used as a bedside reference. Complications caused by pharmaceuticals are dispersed throughout every chapter and the concluding chapters provide a special emphasis on meticulous supportive care of the critically ill patient to allow the best chance for recovery.
Non-Pushing PCI Techniques
by Kazuaki MitsudoThis book provides an in-depth review of non-pushing percutaneous coronary intervention (PCI). With abundant, clear figures, the chapters logically describe retrograde wiring techniques, including the stenting of bifurcation lesions, right coronary artery ostial lesions, and left main trunk (LMT) lesions, and then go on to illustrate Mitsudo’s non-pushing PCI techniques. Short columns between chapters offer tips and tricks to help readers gain a better understanding.Given its scope, this book is not only a valuable resource for by coronary interventionalists dealing with PCI for complex lesions including chronic total occlusion (CTO), but also serves as a practical and informative for cardiologists.
Non-Representational Geographies of Therapeutic Art Making
by Candice P. BoydUtilising non-representational theories and practice-led research methods, this book serves to reclaim therapeutics as ecological, spatial and material. It examines the sites and performances of a wide range of therapeutic art practices, including painting and drawing, dance movement therapy, fibre art, subterranean graffiti practice, and poetic permaculture. In doing so it provides an important assessment of the role and status of therapy in contemporary life. A highly interdisciplinary text, Boyd’s research is informed by a thorough reading of post-structural theory including contemporary feminism, Guattari’s ethico-aesthetic paradigm, Whitehead’s process-oriented ontology, and Deleuze’s writing on sense and the event. This innovative study will prove essential for scholars and practitioners of cultural geography, socially-engaged art, therapeutic studies, and occupational therapy.
Non-Sighted and Sighted Adults' Volumetric Perceptions of Functional Objects
by T. M. Nelson C. J. Ladan J. EppsA report on the study of the manner in which sighted, sighted-but-blindfolded, late-blind (subsequent to 7 years of age), and congenitally blind (blind since birth) persons employ physical parameters in determining weight and volume of functional objects.
Non-Steroidal Anti-Inflammatory Drugs in Water: Emerging Contaminants and Ecological Impact (The Handbook of Environmental Chemistry #96)
by Leobardo Manuel Gómez-OlivánThis book gathers the main international research findings on non-steroidal anti-inflammatory drugs (NSAIDs) as emerging contaminants in water. It focuses on the major routes of exposure, and the destinations and life cycles of NSAIDs in water, as well as the manifestations of toxicity in different organisms. It also reviews the methods used in the detection, analysis and quantification of NSAIDs in water as well as the biological and chemical methods of removing them. Lastly, the book offers an overview of the legal frameworks in place and provides conclusions and recommendations for the future. Given its scope, the book is an indispensable resource for scientists in academia and industry, as well as for decision-makers involved in contamination assessment and environmental analysis and NGOs interested in the problem of water contamination by NSAIDs.
Non-Suicidal Self-Injury in Eating Disorders
by Laurence Claes Jennifer J. MuehlenkampNon-suicidal self-injury and eating disorders represent significant problems among today's youth and pose unique challenges for clinicians, particularly when they co-occur. This book is a rare resource in that it provides cutting-edge information on the interactions between self-injury and disordered eating, empirically informed treatments for the co-occurrence of these behaviors, and specific topics relevant to understanding nuances in the risk factors, treatment, and prevention of both self-injury and eating disorders. Practitioners, graduate students, and researchers working within this specialized area will find this text to be instrumental in advancing their knowledge and improving the treatment of self-injury in those with eating disorders.
Non-Surgical Control of Periodontal Diseases
by Paul A. Levi Y. Natalie Jeong Robert J. Rudy Daniel K. ColemanThis handbook has been designed for practicing dental clinicians and students, which includes dental hygienists, general dentists, periodontists, and students of dental hygiene and dentistry who are responsible for treating patients with a broad spectrum of periodontal diseases. The book will enable practicing clinicians and students to successfully meet the challenge of excellent patient care, by providing , in a concise and simplified format, both classic and contemporary practical measures that address all aspects of non-surgical periodontal disease management. Readers are carefully guided through an extensive body of accumulated knowledge in eight broad chapters which includes: the patient's involvement in disease control and prevention, the clinician's instrumentation for the diagnosis and basic treatment of gingivitis/periodontitis along with pharmacotherapeutics and supportive maintenance therapy to ensure long-term success. Numerous illustrations help to bring the presented ideas and suggestions to life and the succinct nature of the text will allow readers to transfer useful information quickly to their own clinical settings.
Non-Surgical Rejuvenation of Asian Faces
by Souphiyeh SamizadehThis book provides a practically applicable guide to facial aesthetics, non-surgical treatment and enhancement in patients of Asian descent. The available evidence base for the use of a range of available techniques when treating an Asian patient is presented and relevant aspects of facial analysis, treatment planning and provision are covered. Detailed instruction is given on how to use cutting edge techniques enabling the reader to develop a thorough understanding of how to proficiently perform these approaches in their clinical practice. Non-Surgical Rejuvenation of Asian Faces systematically reviews the evidence base for and details how to use the latest available non-surgical techniques for facial rejuvenation in this group of patients. It is a valuable resource for aesthetic medicine professionals and trainees alike seeking a reference on the topic.
Non-Surgical Rhinoplasty (The PRIME Series)
by Ali Pirayesh Dario Bertossi Riccardo Nocini*Brings together all a surgeon needs to know for safe and effective non-invasive rhinoplasty *Offers a one-stop resource for surgeons wishing to add injection techniques to their practice *Presents a master-class from world experts
Non-Surgical Thread Procedures: The Future of Aesthetic Medicine
by Nancy M. KimThis book provides knowledge and instruction about thread procedures that are the current state of the art in the United States. The book offers a comprehensive overview of the threads available and in favor of use in the US. The chemical and biological activity of the threads also will be explained. Chapters will discuss research that support the theory and clinical efficacy of the threads, thus laying the foundation for understanding the purpose of the threads. Chapters discuss the different types, sizes and styles of threads in current use. The various areas and procedures that are possible with the threads will be described in detail to allow practitioners a greater comfort level when learning these procedures. The book will also include tips to help practitioners succeed with these procedures as it is generally not as straight forward as some other aesthetic procedures. In addition, the book compares and contrasts thread procedures with other current modalities. This will delineate the advantages of threads over other treatments for aesthetic treatment including surgery. The book also contains multiple videos that show the use of threads in various procedures.Non-Surgical Thread Procedures is a must-have resource for clinicians and physicians that practice minimally invasive aesthetic procedures as well as those interested in thread procedures.
Non-Surgical Treatment of Keratinocyte Skin Cancer
by Gregor Jemec Lajos Kemeny Donald MiechWith more and more patients suffering from field cancerisation, an alternative for repeated surgery for the diagnosis and treatment of non-melanoma skin cancer is becoming necessary. Although surgery remains the gold standard for treatment of non-melanoma or keratinocyte skin cancer, it also has its downside. Surgery leaves scars and nowadays the cosmetic outcome of therapy is becoming increasingly important. Since many cases can effectively be managed without surgery, the possibilities of non-surgical therapy are gaining popularity, particularly in low malignancy tumours. This reader-friendly clinical guide offers treatment options for the growing group of these patients. It describes the current state-of-the art for non-surgical treatment of this type of skin cancer, and gives factual knowledge to beginners and new inspirations to experts.
Non-Traditional Feeds for Use in Swine Production (CRC Press Revivals)
by Phillip A Thacker Roy N KirkwoodFeed represents the single greatest expense associated with bringing pigs to market weight. Therefore, if you can reduce the cost of feeding without detriment to pig performance, the economics of swine production will improve. The ingredient list for swine rations has become fairly limited, and the majority of diets fed to pigs consist of a few staples, such as corn, wheat, barley, and soybean meal. Non-Traditional Feeds for Use in Swine Production explores over fifty non-traditional feedstuffs in terms of their nutritional content and their viability as alternative, cost effective food sources
Non-Vascular Interventional Radiology of the Abdomen
by Ronald S. ArellanoThis book is designed to provide a foundation for physicians-in-training and a quick guide to further enhance the skills set of practicing interventionalists. It is a concise reference manual covering the major aspects of clinical scenarios, procedures, and techniques. Non-Vascular Interventional Radiology of the Abdomen expertly addresses the planning and execution of commonly encountered procedures, including organ specific biopsies, abscess drainage, urinary interventions, gastrostomy, gastrojejunostomy, and biliary interventions.
Non-Venereal Treponematoses: Global Status 2010 edition
by Dr Stephen Berger Gideon InformaticsNon-Venereal Treponematoses: Global Status is one in a series of GIDEON ebooks which summarize the status of individual infectious diseases, in every country of the world. Data are based on the GIDEON database (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing search of the medical literature. Chapters are arranged alphabetically, by country name. Each section is divided into five subsections. 1. Descriptive epidemiology 2. Summary of clinical features 3. Global status of the disease 4. Status of the disease in a specific country 5. References Non-Venereal Treponematoses: Global Status includes separate sections on Endemic syphilis (bejel), Pinta, and Yaws.
Non-Viral Gene Delivery Vectors
by Gabriele CandianiThis volume provides readers with a wide collection of the latest and readily reproducible technical protocols available in the field of non-viral gene delivery vectors. The chapters in this book are organized into three major parts: Part I is a section on conventional bolus gene delivery vectors that introduces typical transfection approaches relying on the addition of transfectants to the cell culture medium where the cells are grown in; Part II covers stimuli-responsive bolus transfectants and topics on gene delivery complexes made of smart polymers or stimuli-responsive polymers that change according to the environment they are in and delivered by dripping into cells; Part III discusses examples of substrate-mediated gene delivery also termed reverse transfection and the immobilization of a gene delivery vector onto a surface as opposed to more typical bolus delivery from the medium. Written in the highly successful "Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, "Non-Viral Gene Delivery Vectors: Methods and Protocols "is written for experimentalists, and is an essential part of many laboratory bookshelves. This book will help novice and professionals alike succeed in their research in this field. "
Non-coding RNA and the Reproductive System
by Dagmar Wilhelm Pascal BernardThis book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.
Non-coding RNAs and Cancer
by Muller FabbriThe discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.
Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer
by Paul HolvoetThis book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine.
Non-coding RNAs in Cardiovascular Diseases (Advances in Experimental Medicine and Biology #1229)
by Junjie XiaoThis book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects. It is particularly useful for researchers and students in the field of non-coding RNA and cardiovascular biology, as well as for cardiologists, pharmacologists and physiologists.
Non-coding RNAs in Colorectal Cancer
by Ondrej Slaby George A. CalinThis is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.