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Older Women With Chronic Pain
by Karen A RobertoThis much-needed book explores the issues and consequences of chronic pain in later life. Chronic pain often accompanies the non-fatal health conditions experienced by older women, but much of the professional literature virtually ignores older chronic pain sufferers. Older Women With Chronic Pain begins to fill this void by exploring chronic pain and its effects on older individuals. Authors draw upon existing pain literature, their knowledge of aging, and recognition of the health issues facing older women to illuminate the particulars of chronic pain in later life in relation to its etiology, assessment, consequences, and management.Chronic pain is not and should not be treated as part of the natural aging process. This book stresses the importance of understanding the causes and consequences of living with chronic pain in later life. Among the specific areas that chapters explore are: physical and biomedical aspects of chronic pain in later life the importance of using a comprehensive strategy for assessing chronic pain in older women coping strategies used by older women with chronic musculoskeletal pain issues associated with cancer pain and pain management in later life the influence of chronic pain on the family relationships of older women nonpharmacologic interventions for the management of chronic pain in older womenThe book includes a thorough review of the geriatric literature as well as suggestions for future research in the area of women with chronic pain. Researchers and academicians interested in the health concerns of older women, and clinicians and practitioners working with older women (and men) with chronic pain will find this book full of insightful information to help them in their work.
Olds' Maternal-Newborn Nursing & Women's Health Across the Lifespan (9th Edition)
by Marcia L. London Patricia A. Wieland Ladewig Michele R. DavidsonThis family-focused text that provides comprehensive coverage of maternal-newborn nursing and women’s health with special attention to evidence-based practice, cultural competence, critical thinking, professionalism, patient education, and home/community care. Accurate, readable, personal, and engaging, OLDS' MATERNAL-NEWBORN NURSING & WOMEN'S HEALTH ACROSS THE LIFESPAN, 9/e reflects a deep understanding of pregnancy and birth as normal life processes, and of family members as partners in care. This edition includes a deeper discussion of childbirth at risk; four new nursing care plans; updated coverage of contraception, complementary/alternative therapies, and much more. New teaching features include Professionalism in Practice and Health Promotion Education boxes, Clinical Judgment case studies, and Critical Thinking questions. This edition also aligns more closely with AACN’s Essentials of Baccalaureate Education for Professional Nursing Practice.
Ole Doc Methuselah
by L. Ron HubbardExplore exotic new worlds in the celebrated and enduring classic of space travel on a cosmic scale, Ole Doc Methuselah mixes equal parts of vivid action, spectacle and mystery and a broad vein of humor to chronicle the voyages and exploits of Ole Doc Methuselah and his unique alien companion, Hippocrates. Ole Doc journeys through the universe as a member of the elite Soldiers of Light, a heroic physician who fights the disease, corruption and social/political upheavals that have spread through mankind's lost planetary colonies. "Classic adventures by a classic writer." --Roger Zelazny
Olfaction in Animal Behaviour and Welfare
by Birte Nielsen Dr Luisa Amo Dr Raimund Apfelbach Dr J. Elizabeth Bolhuis Dr Vincent Bombail Dr Roisin Campbell-Palmer Dr Caroline Clouard Dr Laurent Dormont Dr Markus Fendt Dr Peter Hepper Dr Tadeusz Jezierski Dr Olivia Le Moëne Dr Frédéric Levy Dr Nicolas Meunier Dr Raymond Nowak Dr Marije Oostindjer Dr Olivier Rampin Dr Frank Rosell Dr Roland Salesse Dr Burton Slotnick Dr Deborah Wells Dr Tristram D. WyattEvidence-based, yet entirely practical, this important new text builds upon the basics of neuroscience to describe the links between olfaction and animal behaviour, and the effects of odours in animal welfare. Animals use smells in a multitude of ways: to orientate themselves, to create social bonds, to recognise food, to initiate reproduction, and to avoid predators and imminent threats such as fire. Starting from the scientific basis of olfaction and odour perception, the book covers pheromones and behavioural tests, before describing the role of olfaction in feeding behaviour, reproduction, disease detection, and animal housing. The book: · is written in an evidence-based way, yet with an easy-to-understand style, making it accessible to non-experts · focuses on animals managed by humans, i.e. farm, zoo, lab and companion species · is illustrated by in-depth research examples of many different species This is a captivating introduction to the world of smells, suitable for advanced students, researchers, and teachers of applied ethology, animal welfare and veterinary science.
Olfaction: An Interdisciplinary Perspective from Philosophy to Life Sciences (Human Perspectives in Health Sciences and Technology #4)
by Nicola Di Stefano Maria Teresa RussoThis book offers a broad and timely perspective on research on olfaction and its current technological challenges. It specifically emphasizes the interdisciplinary context in which olfaction is investigated in contemporary research. From aesthetics to sociology, from bioengineering to anthropology, the different chapters discuss a wide variety of issues arising from olfaction research and its application in different contexts. By highlighting the overlaps between different areas of research, the book fosters a better communication between disciplines and leads towards a better understanding of the role of olfaction in human perception and cognition. This inspiring read is of interest to students, researchers and practitioners in psychology, philosophy, bioengineering, and cultural studies.
Olfactory Receptors
by Chiquito J. CrastoDespite the best efforts of many and despite landmark discoveries and experimental ingenuity, challenges in the pursuit of research related to olfactory receptors (ORs) continue to exist. In Olfactory Receptors: Methods and Protocols, experts in the field contribute chapters that serve to address these challenges. The volume consists of several sections: knowledge dissemination of ORs, theoretical assessments of OR structure and function, as well as development and use of expression systems and experimental functional analysis. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and practical, Olfactory Receptors: Methods and Protocols seeks to aid researchers in furthering the knowledge of olfaction and moving us ever closer to the thrilling discoveries that will follow.
Olfactory Receptors: Methods and Protocols (Methods in Molecular Biology #1820)
by Fabio Marques Simoes de Souza Gabriela AntunesThis detailed volume explores olfactory receptors, a topic that goes beyond classical biochemical essays and involves methods to investigate the brain areas associated with the perception of odorants. Gathering the strands of many advanced techniques, the book organizes these key methods in order to achieve a unifying comprehension of the olfactory system. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and multidisciplinary, Olfactory Receptors: Methods and Protocols serves to benefit not only those who are beginning in the field of olfactory receptors, but also those who are already working in the field and that want to learn another advanced techniques.
Olfactory Research in Dogs
by Lucia LazarowskiThis book unites cutting-edge research related to various aspects of dog olfaction. It includes rich expertise about detection dogs with application perspectives, and expands beyond.In four clearly arranged sections, readers will discover specialist contributions on:the fundamentals of olfaction, anatomy, comparative olfactory neuroscience and dysfunctionmethodological reflections on canine olfactometry and essential implications for practice, comprising dog selection for scent detection, handler bias and signal detection conceptsthe connection with dog behavior, cognition, welfare, and learning and training methodsdiverse application examples of dog olfactory capabilities, such as disease detection for diagnostics, infectious disease surveillance, forensics and ecological conservationThe unique and exciting link between science and practice makes this book a valuable read not only for researchers, but also for practicing veterinarians and professionals in the fields of canine detection, chemical sensing, working dog behavior and welfare.
Olga: A Novel
by Prof Bernhard SchlinkA #1 INTERNATIONAL BESTSELLER'Bernhard Schlink speaks straight to the heart' New York Times'Brilliant... A tale of love and loss in 20th century Germany' Evening Standard'A cleverly-constructed tale of cross-class romance' Mail on Sunday'A poignant portrait of a woman out of step with her time' Observer Olga is an orphan raised by her grandmother in a Prussian village around the turn of the 20th century. Smart and precocious, she fights against the prejudices of the time to find her place in a world that sees her as second-best.When she falls in love with Herbert, a local aristocrat obsessed with the era's dreams of power, glory and greatness, her life is irremediably changed.Theirs is a love against all odds, entwined with the twisting paths of German history, leading us from the late 19th to the early 21st century, from Germany to Africa and the Arctic, from the Baltic Sea to the German south-west.This is the story of that love, of Olga's devotion to a restless man - told in thought, letters and in a fateful moment of great rebellion.
Oligodendrocytes: Methods and Protocols (Methods in Molecular Biology #1936)
by David A. Lyons Linde KegelThis volume looks at the study of oligodendrocytes through in vitro and in vivo techniques, multiple model organisms, using approaches that bridge scales from molecular through system. Chapters in this book cover topics such as fundamental molecular analyses of oligodendrocytes and myelin; in vitro, ex vivo, and in vivo molecular-cellular-electrophysiology-based techniques; oligodendrocyte formation, homeostasis, and disruption in zebrafish and Xenopus; and parallel system-level imaging of animal and human models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, Oligodendrocytes: Methods and Protocols is a valuable reference guide that highlights the expansive and fast-paced nature of research into oligodendrocyte biology underlying health and function.
Oligonucleotide Synthesis
by Piet HerdewijnA collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.
Oligonucleotide-Based Drugs and Therapeutics: Preclinical and Clinical Considerations for Development
by Nicolay Ferrari Rosanne SeguinA comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic science behind antisense oligonucleotides chemistry, toxicology, manufacturing, to safety assessments, the design of therapeutic protocols, to clinical experience. Antisense oligonucleotides are single strands of DNA or RNA that are complementary to a chosen sequence. While the idea of antisense oligonucleotides to target single genes dates back to the 1970's, most advances have taken place in recent years. The increasing number of antisense oligonucleotide programs in clinical development is a testament to the progress and understanding of pharmacologic, pharmacokinetic, and toxicologic properties as well as improvement in the delivery of oligonucleotides. This valuable book reviews the fundamentals of oligonucleotides, with a focus on antisense oligonucleotide drugs, and reports on the latest research underway worldwide. • Helps readers understand antisense molecules and their targets, biochemistry, and toxicity mechanisms, roles in disease, and applications for safety and therapeutics • Examines the principles, practices, and tools for scientists in both pre-clinical and clinical settings and how to apply them to antisense oligonucleotides • Provides guidelines for scientists in drug design and discovery to help improve efficiency, assessment, and the success of drug candidates • Includes interdisciplinary perspectives, from academia, industry, regulatory and from the fields of pharmacology, toxicology, biology, and medicinal chemistry Oligonucleotide-Based Drugs and Therapeutics belongs on the reference shelves of chemists, pharmaceutical scientists, chemical biologists, toxicologists and other scientists working in the pharmaceutical and biotechnology industries. It will also be a valuable resource for regulatory specialists and safety assessment professionals and an important reference for academic researchers and post-graduates interested in therapeutics, antisense therapy, and oligonucleotides.
Oligonucleotide-Based Therapies: Methods and Protocols (Methods in Molecular Biology #2036)
by Olof Gissberg Rula Zain Karin E. LundinThis book provides a collection of comprehensive, up-to-date, and broadly applicable guides to the research and development fields of oligonucleotide (ON) therapeutics. Covering topics from the study of antisense and anti-gene effects to oligonucleotides in the context of drug discovery and development, the volume explores a wide-ranging and useful spectrum of methods and protocols needed to take full advantage of therapeutic applications involving ONs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Oligonucleotide-Based Therapies: Methods and Protocols aims to be a great aid in the laboratory as well as an ideal reference guide when designing antisense and anti-gene oligonucleotides for therapeutic applications.
Oligosaccharides of Chitin and Chitosan: Bio-manufacture and Applications
by Liming ZhaoThe book provides an overview of bio-manufacturing techniques for the production, purification, characterization and modification of chito/chitin oligosaccharides and their monomers. In addition, it explores potential applications in the food, biomedical and agricultural industry on the basis of their bioactivities and biomaterial properties. Lastly, it shares a range of cutting-edge insights to help solve problems in industrial processes and promote further academic investigation. Given its scope, it offers a valuable resource for researchers and graduate students in the fields of bioengineering, food science, biochemistry, etc.
Olive Oil: Minor Constituents and Health
by Dimitrios BoskouEpidemiological studies indicate that the consumption of natural antioxidants from such plant-derived sources as olive oil produces beneficial health effects. Olive Oil: Minor Constituents and Health provides a balanced understanding of the pharmacological properties of phenols and other bioactive ingredients in the composition of olive oil. It dis
Oliver Sacks: The Last Interview
by Oliver SacksAn extraordinary collection of interviews with the beloved doctor and author, whose research and books inspired generations of readers.Oliver Sacks--called "the poet laureate of medicine" by the New York Times--illuminated the mysteries of the brain for a wide audience in a series of richly acclaimed books, including Awakenings and The Man Who Mistook His Wife for a Hat, and numerous The New Yorker articles. In this collection of interviews, Sacks is at his most candid and disarming, rich with insights about his life and work. Any reader of Oliver Sacks will find in this book an entirely new way of looking at a brilliant writer.
Olivia: My Life of Exile in Kalaupapa
by Olivia Robello BreithaOlivia Robello Breitha was diagnosed with Hansen's disease (leprosy) when she was a young woman in the 1930s. At the time, there was no treatment for the disease and in Hawaii many people with leprosy were exiled to Kalaupapa, a community on the island of Molokai. Breitha, who had a 6th grade education, wrote her powerful story about living with the disease. At times they were treated inhumanely, mostly by doctors and medical professionals, and Breitha was unafraid to fight for patient rights and reducing stigma.
Omega Balance: Nutritional Power for a Happier, Healthier Life (A Johns Hopkins Press Health Book)
by Anthony John HulbertLearn how to live a happier and healthier life by finding the right balance of omega fatty acids in your diet.Omega-3 and omega-6 fatty acids are essential in the human diet. In Omega Balance, noted scientist Anthony J. Hulbert explains how the balance between these fatty acids in the human food chain has changed over the last half-century and the very serious negative health impacts this imbalance has created. An imbalance of these omega fats contributes to increased rates of obesity, diabetes, cardiovascular diseases, allergies, asthma, as well as cancer and a variety of other inflammatory diseases. Omega balance is also important for normal brain function, and an imbalance in these fatty acids is associated with depression, mood disorders, and neurodegenerative diseases. Hulbert provides extensive information on the omega balance of different foods and discusses fascinating details about human evolution, dietary changes throughout history, the effect of diet on human development and physiological processes, and more. He investigates the paleo diet of our ancestors and describes the dramatic changes that have accompanied the increased ultra-processing of modern foods. Omega Balance is an essential guide to understanding a significant problem in our modern food chain and will make us rethink the food we eat.
Omega-3 Fatty Acids
by Mahabaleshwar V. Hegde Anand Arvind Zanwar Sharad P. AdekarThis volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.
Omega-3 Fatty Acids and the DHA Principle
by Raymond C. Valentine David L. ValentineThe physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carrie
Omega-3 Fatty Acids in Health and Disease
by Robert S. LeesA report from research in the MIT Sea Grant College Program. Discusses the relationship between particular fatty acids found only in fish oil, and human health. Presents and evaluates information on the health effects of dietary fats generally; evidence that fish oil consumption affects the incidenc
Omega-3 Fatty Acids: Keys to Nutritional Health and Disease
by Mahabaleshwar V. Hegde Anand Arvind Zanwar Sharad P. AdekarThis book argues for the importance of omega-3 fatty acids in our diet. Omega-3 fatty acids are a must in our daily diet, as the human body cannot synthesize it. The human body is crippled in evolution; we are deprived of the genes that are needed to synthesize these vital molecules. Except for regular fish eaters, the majority of the human population does not get adequate omega-3 fatty acid in their food. Fatty acids provide a structural framework for cells, tissues, and organs, as well as the building blocks for several bioactive ingredients, and they provide a wide range of benefits from general improvements in health to protection against inflammation and disease. Omega-3 Fatty Acids discusses various sources of omega-3 fatty acid, health implications of omega-3 fatty acid intake, and remedial measures that can improve diet for those lacking in fatty acids. The book opens with a discussion of various sources of omega-3 fatty acids, such as flaxseed, milk, eggs, and marine algae. Following this, is a detailed discussion of the effect omega-3 intake has on different conditions, like pregnancy, psoriasis, aging disorders, cardiovascular events, obesity, and non-communicable diseases, such as diabetes and Alzheimer’s. This much-expanded edition includes new chapters on topics such as the linoleic-to-linolenic dietary intake ratio, the role of omega-3 fatty acids in eye health, the effects of omega-3 fatty acids on metabolic syndrome and fatty liver disease, and the influence of omega-3 fatty acids on bone turnover and energy metabolism. An indispensable text designed for nutritionists, dietitians, clinicians and health-related professionals, Omega-3 Fatty Acids presents a comprehensive assessment of the current knowledge about the nutritional effects of omega-3 fatty acids and their delivery in foods.
Omega-6/3 Fatty Acids
by Ronald Ross Watson Sherma Zibadi Fabien De MeesterOver the last several years developing human research suggests that a component of omega-3 fatty acids, long chain ones, contribute particularly to health benefits. Omega-6/3 Fatty Acids: Functions, Sustainability Strategies and Perspectives focuses on developing information on this newly recognized key component. This volume uniquely, and for the first time, focuses on sustainability of natural sources of omega-3 fatty acids variants including long chain ones, and on ways to increase their use and availability to reduce major diseases. The authors review cardiovascular disease, neurological changes and mental health and other diseases like diabetes where long chain omega-3 fatty acids play protective roles from recent human trials. Each chapter evaluates developing information on the possible mechanistic role of long chain omega-3 fatty acids. After showing their requirement and involvement in health promotion there are reviews of various sources and ways to protect and promote them. Authors provide support for the benefits and sources of long chain omega-3 fatty acids and their increased dietary intake that reduce various physical and mental illnesses. Omega-6/3 Fatty Acids: Functions, Sustainability and Perspectives is a unique and important new volume that provides the latest data and reviews to physicians who need to assess serum omega-6/3 and fatty acids to help diagnose risks and change diets and to inform industry and the scientific community with reviews of research for actions including new studies and therapies.
Omgaan met een scheiding
by J.P. van de Ven BVEr gaan in Nederland elke dag driehonderd stellen uit elkaar (dit zijn op jaarbasis 219. 000 mensen). Zij raken veelal verwikkeld in het afhandelen van allerhande juridische en praktische zaken. Maar over gevoelens zoals verwarring, angst, woede, wantrouwen, jaloezie, verdriet, opluchting, schuld en schaamte die met een scheiding gepaard gaan, en over hoe je daarmee omgaat is weinig informatie voorhanden. Het boek omgaan met een scheiding voorziet hierin. Het behandelt de gevolgen van een scheiding op emotioneel, mentaal en sociaal gebied.
Omgaan met hoogtevrees.
by S. J. Swaen Vogelbescheming Nederland W. A. Sterk IpzoHoogtevrees is een van de bekendste vormen van angst. De klachten treden niet alleen op grote hoogtes op. Sommige mensen durven bijvoorbeeld niet in diep helder water te zwemmen of hebben moeite om naar een kerktoren op te kijken. Iedereen heeft in zekere mate last van hoogtevrees. Hoogtes kunnen gevaarlijk zijn en het is dan ook logisch om op grote hoogte op je hoede te zijn. Maar wanneer de angst uit de hand loopt en je bang wordt in situaties die geen angst hoeven op te wekken, dan belemmert de hoogtevrees je dagelijks leven. Mensen met hoogtevrees gaan immers steeds meer situaties uit de weg waarin ze met hoogteverschillen te maken kunnen krijgen. Overmatige hoogtevrees is daarom een vervelende klacht, maar doorgaans goed te verhelpen. Dit boek laat zien dat iedereen met wat motivatie, begeleiding en tijdsinvestering zijn hoogtevrees onder controle kan krijgen. Hierbij wordt uitgegaan van de principes van de gedragstherapie. Door de stapsgewijze beschrijving van de gedragstherapeutische weg met duidelijke tips en opdrachten is Omgaan met hoogtevrees een waardevol zelfhulpboek. De heldere beschrijvingen van andere therapieën met een indicatie van de effectiviteit ervan maken het ook een handige wegwijzer voor wie liever een beroep doet op de hulpverlening. Omgaan met hoogtevrees verschijnt in de reeks Van A tot ggZ.