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PACS and Digital Medicine: Essential Principles and Modern Practice
by Yu Liu Jihong WangTo improve efficiency and reduce administrative costs, healthcare providers, insurance companies, and governments are increasingly using integrated electronic health record (EHR) and picture archiving and communication systems (PACS) to manage patients' medical information. Reflecting the latest applications of PACS technology, PACS and Digital Med
PACS and Imaging Informatics
by H. K. HuangThe definitive guide to PACS -- now with more clinically applicable materialIn recent years, the field of picture archiving and communications systems--PACS--and image informatics has advanced due to both conceptual and technological advancements. This edition of PACS and Imaging Informatics: Basic Principles and Applications addresses the latest in this exciting field. In contrast to the previous edition, this updated text uses the framework of image informatics, not physics or engineering principles, to explain PACS. It is the only resource that thoroughly covers the critical issues of hardware/software design and implementation in a systematic and easily comprehensible manner.To strengthen and update the book, the author:Emphasizes clinical applications of PACS and integrates clinical examples throughout the textReflects the many changes in the field, with new chapters on Web-based PACS, security, integrating the healthcare enterprise, clinical management systems, and the electronic patient recordUses the framework of imaging informatics to explain PACS, making the book accessible to those without advanced knowledge of physics, engineering, math, or information technologyExplains how PACS can improve workflow, therapy, and treatmentWith the most systematic and thorough coverage of practical applications available, this text is the complete guide for all those involved in designing, implementing, and using PACS. Professionals in medical and allied health imaging informatics; radiologists and their technical staff; surgeons and oncologists and their teams; medical and electronic engineers; medical informaticians; and fellows, graduate students, and advanced undergraduates will all benefit from this valuable resource."An excellent book for people involved in the design, implementation, or simply the operations of PACS and an appropriate textbook."--From a review of the previous edition in IEEE Engineering in Medicine and Biology"The strength of the book lies in the vast experience of the author, who has implemented PACS at numerous institutions in the United States and abroad."--From a review of the previous edition in Radiology
PACS-Based Multimedia Imaging Informatics: Basic Principles and Applications
by H. K. HuangThoroughly revised to present the very latest in PACS-based multimedia in medical imaging informatics—from the electronic patient record to the full range of topics in digital medical imaging—this new edition by the founder of PACS and multimedia image informatics features even more clinically applicable material than ever before. It uses the framework of PACS-based image informatics, not physics or engineering principles, to explain PACS-based multimedia informatics and its application in clinical settings and labs. New topics include Data Grid and Cloud Computing, IHE XDS-I Workflow Profile (Integrating the Healthcare Enterprise Cross-enterprise Document Sharing for Imaging), extending XDS to share images, and diagnostic reports and related information across a group of enterprise health care sites. PACS-Based Multimedia Imaging Informatics is presented in 4 sections. Part 1 covers the beginning and history of Medical Imaging, PACS, and Imaging Informatics. The other three sections cover Medical Imaging, Industrial Guidelines, Standards, and Compliance; Informatics, Data Grid, Workstation, Radiation Therapy, Simulators, Molecular Imaging, Archive Server, and Cloud Computing; and multimedia Imaging Informatics, Computer-Aided Diagnosis (CAD), Image-Guide Decision Support, Proton Therapy, Minimally Invasive Multimedia Image-Assisted Surgery, BIG DATA. New chapter on Molecular Imaging Informatics Expanded coverage of PACS and eHR's (Electronic Health Record), with HIPPA compliance New coverage of PACS-based CAD (Computer-Aided Diagnosis) Reorganized and expanded clinical chapters discuss one distinct clinical application each Minimally invasive image assisted surgery in translational medicine Authored by the world's first and still leading authority on PACS and medical imaging PACS-Based Multimedia Imaging Informatics: Basic Principles and Applications, 3rd Edition is the single most comprehensive and authoritative resource that thoroughly covers the critical issues of PACS-based hardware and software design and implementation in a systematic and easily comprehensible manner. It is a must-have book for all those involved in designing, implementing, and using PACS-based Multimedia Imaging Informatics.
PALEO: It's not a diet, it's a lifestyle
by Cassandra Rodriguez Tomas Pulido GalanDon't start a diet that will finish someday, start a lifestyle that lasts forever. Forget about counting calories, starving and tasteless food. Gain health, vitality, strength, improve your appearance, live better and longer. Question the established dogmas. Stand up to the food industry, Join the revolution. Welcome to the tribe.
PAMP Signals in Plant Innate Immunity
by P. VidhyasekaranPlant innate immunity is a potential surveillance system of plants and is the first line of defense against invading pathogens. The immune system is a sleeping system in unstressed healthy plants and is activated on perception of the pathogen-associated molecular patterns (PAMP; the pathogen's signature) of invading pathogens. The PAMP alarm/danger signals are perceived by plant pattern-recognition receptors (PRRs). The plant immune system uses several second messengers to encode information generated by the PAMPs and deliver the information downstream of PRRs to proteins which decode/interpret signals and initiate defense gene expression. This book describes the most fascinating PAMP-PRR signaling complex and signal transduction systems. It also discusses the highly complex networks of signaling pathways involved in transmission of the signals to induce distinctly different defense-related genes to mount offence against pathogens.
PARP Inhibitors for Cancer Therapy
by Nicola J. Curtin Ricky A. SharmaPARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The "synthetic lethality" of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.
PARP as a Therapeutic Target (Handbooks in Pharmacology and Toxicology)
by Jie ZhangRecent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati
PAT Applied in Biopharmaceutical Process Development And Manufacturing: An Enabling Tool for Quality-by-Design (Biotechnology and Bioprocessing)
by Jose C. Menezes Cenk Undey Duncan Low Mel KochAs with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the rapid growth in the biopharmaceutical area and the comp
PBX Security and Forensics
by I. I. AndroulidakisPBX Security and Forensics presents readers with theoretical and practical background for Private Branch Exchanges (PBXs). PBX is privately owned equipment that serve the communication needs of a private or public entity making connections among internal telephones and linking them to other users in the Public Switched Telephone Network (PSTN). Targeted damages and attacks in PBXs can cause significant instability and problems. The author provides examples of these threats and how to prevent against such attacks in the future. Readers will also be shown where to find forensics data and how to conduct relevant analysis.
PCAT Prep Plus 2018-2019: 2 Practice Tests + Proven Strategies + Online (Kaplan Test Prep)
by Kaplan Test PrepKaplan's PCAT Prep Plus 2018–2019 includes all the content and strategies you need to get the PCAT results you want. Kaplan Test Prep is the only Official Provider of PCAT Prep, as endorsed by the American Association of Colleges of Pharmacy (AACP).The Best Review2 full-length, realistic practice tests online that provide you with scores and percentilesA guide to the current PCAT Blueprint to show you exactly what to expect on Test DayAdditional practice questions for every subject, all with detailed answers and explanationsComprehensive review of all the content covered on the PCAT:WritingBiologyGeneral ChemistryOrganic ChemistryBiochemistryCritical ReadingQuantitative ReasoningKaplan's proven strategies for Test Day successExpert GuidanceKaplan's expert psychometricians ensure our practice questions and study materials are true to the test.We invented test prep—Kaplan (www.kaptest.com) has been helping students for almost 80 years. Our proven strategies have helped legions of students achieve their dreams.
PCAT Prep Plus 2020-2021: 2 Practice Tests + Proven Strategies + Online (Kaplan Test Prep)
by Kaplan Test PrepKaplan's PCAT Prep Plus 2020-2021 includes all the content and strategies you need to get the PCAT results you want. Kaplan Test Prep is the only Official Provider of PCAT Prep, as endorsed by the American Association of Colleges of Pharmacy (AACP).PCAT announced minor changes to the exam for the July 2018 test dates going forward – the timing of three of the sections has increased, giving you more time per question, a greater emphasis on passage-based questions in the science sections, more real-life problems in the Quantitative Reasoning section, and non-science based passages in Reading Comprehension. We have already updated the timing on the included Full-Length practice tests with PCAT Prep Plus to match the test as well as aligned the science sections with the increase in passage-based questions. Rest assured that the changes still align with the effective prep you'll get from Kaplan's PCAT Prep Plus as the core skills and content tested has not changed. To see the new timing of the exam visit kaptest.com/study/pcat/all-about-the-pcat/The Best Review2 full-length, realistic practice tests online that provide you with scores and percentilesA guide to the current PCAT Blueprint to show you exactly what to expect on Test DayAdditional practice questions for every subject, all with detailed answers and explanationsComprehensive review of all the content covered on the PCATKaplan's proven strategies for Test Day successExpert GuidanceKaplan's experts ensure our practice questions and study materials are true to the test.We invented test prep—Kaplan (www.kaptest.com) has been helping students for 80 years. Our proven strategies have helped legions of students achieve their dreams.
PCAT Prep Plus: 2 Practice Tests + Proven Strategies + Online (Kaplan Test Prep)
by Kaplan Test PrepKaplan's PCAT Prep Plus, Third Edition is up-to-date with the latest test changes and includes all the content and strategies you need to get the PCAT results you want. Kaplan Test Prep is the only Official Provider of PCAT Prep, as endorsed by the American Association of Colleges of Pharmacy (AACP). We are so certain that PCAT Prep Plus offers all the knowledge you need to excel at the PCAT that we guarantee it: After studying with the online resources and book, you'll score higher on the PCAT—or you'll get your money back.The Best Review2 full-length, realistic practice tests online that provide you with scores and percentilesA guide to the current PCAT Blueprint to show you exactly what to expect on Test DayAdditional practice questions for every subject, all with detailed answers and explanationsComprehensive review of all the content covered on the PCATKaplan's proven strategies for Test Day successExpert GuidanceKaplan's experts ensure our practice questions and study materials are true to the test.We invented test prep—Kaplan (kaptest.com) has been helping students for 80 years. Our proven strategies have helped legions of students achieve their dreams.
PCAT Test Prep Flash Cards: Algebra Essentials (Exambusters PCAT Workbook #2 of 4)
by Ace Inc.<P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i><P><P> 450 questions and answers that highlight introductory algebra definitions, problems, and concepts.<P><P> Topics: Algebraic Concepts, Sets, Variables, Exponents, Properties of Numbers, Simple Equations, Signed Numbers, Monomials, Polynomials, Additive and Multiplicative Inverse, Word Problems, Prime Numbers, Factoring, Algebraic Fractions, Ratio and Proportion, Variation, Radicals, Quadratic Equations <P>Exambusters PCAT Prep Workbooks provide comprehensive, fundamental PCAT review--one fact at a time--to prepare students to take practice PCAT tests. Each PCAT study guide focuses on one specific subject area covered on the PCAT exams. From 300 to 600 questions and answers, each volume in the PCAT series is a quick and easy, focused read. Reviewing PCAT flash cards is the first step toward more confident PCAT preparation and ultimately, higher PCAT exam scores!
PCAT Test Prep Flash Cards: Arithmetic Essentials (Exambusters PCAT Workbook #1 of 4)
by Ace Inc.<P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i><P><P> 600 questions and answers highlight essential arithmetic definitions, problems, and concepts. <P><P>Topics: Addition, Subtraction, Multiplication, and Division of Whole Numbers; Fractions and Decimals, Multiplication Tables, Word Problems, Percents, Measurement, Metric System, Square Roots and Powers, Real Numbers, Properties of Numbers<P>Exambusters PCAT Prep Workbooks provide comprehensive, fundamental PCAT review--one fact at a time--to prepare students to take practice PCAT tests. Each PCAT study guide focuses on one specific subject area covered on the PCAT exams. From 300 to 600 questions and answers, each volume in the PCAT series is a quick and easy, focused read. Reviewing PCAT flash cards is the first step toward more confident PCAT preparation and ultimately, higher PCAT exam scores!
PCAT Test Prep Flash Cards: Biology Essentials (Exambusters PCAT Workbook #3)
by Ace Inc.<P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i><P><P> 450 questions and answers (ILLUSTRATED). Essential definitions and concepts. <P><P>Topics: Cells, Biochemistry and Energy, Evolution and Classification, Kingdoms: Bacteria, Fungi, Protista; Kingdom: Plantae, Kingdom: Animalia, Human Locomotion, Human Circulation and Immunology, Human Respiration and Excretion, Human Digestion, Human Nervous System, Human Endocrinology, Reproduction and Development, Genetics, Ecology <P>Exambusters PCAT Prep Workbooks provide comprehensive, fundamental PCAT review--one fact at a time--to prepare students to take practice PCAT tests. Each PCAT study guide focuses on one specific subject area covered on the PCAT exams. From 300 to 600 questions and answers, each volume in the PCAT series is a quick and easy, focused read. Reviewing PCAT flash cards is the first step toward more confident PCAT preparation and ultimately, higher PCAT exam scores!
PCAT Test Prep Flash Cards: Chemistry Essentials (Exambusters PCAT Workbook #4 of 4)
by Ace Inc.<P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. Benetech is actively working on projects to improve accessibility issues such as these.</i><P><P> 700 questions and answers. Essential definitions, formulas, concepts, and sample problems. <P><P>Topics: Introduction, Matter, Atoms, Formulas, Moles, Reactions, Elements, Periodic Table, Electrons, Chemical Bonds, Heat, Gases, Phase Changes, Solutions, Reaction Rates, Equilibrium, Acids and Bases, Oxidation and Reduction, Introduction to Organic Chemistry, Radioactivity <P>Exambusters PCAT Prep Workbooks provide comprehensive, fundamental PCAT review--one fact at a time--to prepare students to take practice PCAT tests. Each PCAT study guide focuses on one specific subject area covered on the PCAT exams. From 300 to 600 questions and answers, each volume in the PCAT series is a quick and easy, focused read. Reviewing PCAT flash cards is the first step toward more confident PCAT preparation and ultimately, higher PCAT exam scores!
PCBs: Human and Environmental Disposition and Toxicology
by Takeshi Nakano Paul S Cooke Tomas Tmovec Deborah C Rice Linda S Birnbaum Charles S WongThough polychlorinated biphenyls (PCBs) have been banned in the United States for more than thirty years, the toxic effects of their presence in local environments continue to be a significant public health concern. PCBs: Human and Environmental Disposition and Toxicology brings together more than fifty established specialists on PCB toxicity to discuss recent trends and specialized investigations of PCB influences on the environment and on humans. Renowned scientists including Paul S. Cooke, Takeshi Nakano, Tomas Trnovec, Deborah C. Rice, Linda S. Birnbaum, and Charles S. Wong present cutting-edge research on Hudson River PCBs, human contamination, homologue profiles, high PCB exposure in Slovakia, and PCB effects on the thyroid hormone, nutrition, and estrogen levels in humans and animals. Focusing on the detection, movement, metabolism, toxicity, remediation, and risk assessment of PCB contamination, this multi-disciplinary study is a valuable resource for regulatory agencies and scientists working with PCBs.
PCR Detection of Microbial Pathogens
by Mark WilksPCR methods for the detection of microbial pathogens have made relatively little impact in diagnostic microbiology laboratories due to the common decision to use expensive commercially produced tests rather than the cheaper alternative of developing one's own tests or introducing tests developed by other workers. PCR Detection of Microbial Pathogens, Second Edition presents alternatives to commercially produced PCR methods to detect microbial pathogens. Although most of the chapters in this book are devoted to the detection of specific pathogens, the first chapters in this book should appeal to anyone working in this field regardless of their particular interests. Although PCR tests can often be made to work with relatively little effort, it is often unclear how efficient the PCR test is, how inhibitory the specimen containing the pathogen of interest is and how the test can be quality controlled. All of which are of great importance in developing tests for diagnostic use. These topics are covered in great depth at the beginning of the book. The main part of the book is devoted to describing methods for the detection of a wide range of pathogens and from widely different specimens and situations. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, PCR Detection of Microbial Pathogens, Second Edition serves microbiologists regardless of their particular interest because, when used together with the general principles, the sheer variety of procedures provided here enables the reader to design and introduce diagnostic tests in the laboratory with confidence.
PCR Mutation Detection Protocols
by Ralph Rapley Bimal D. TheophilusApplication of DNA technology to the identification of disease-causing mutations has become widespread in recent years. PCR Mutation Detection Protocols, provides biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Additional coverage is given to the direct use of DNA sequencing as a detection method in its own right and to the characterization of mutations previously located by other screening techniques. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution. <P><P> Comprehensive and highly practical, PCR Mutation Detection Protocols assures both seasoned and novice investigators access to the highly productive and readily reproducible PCR-based mutation detection methods, techniques that are laying the groundwork for many of today's major scientific and medical advances.
PCR Mutation Detection Protocols, 2nd Edition
by Ralph Rapley Bimal D. TheophilusSince the publication of the popular first edition, the explosion of DNA sequence information, the access to bioinformatics and mutation databases coupled with the ability to readily detect and confirm mutations has cemented the role of molecular diagnostics in medicine and, in particular, mutation detection by the polymerase chain reaction (PCR). In PCR Mutation Detection Protocols, Second Edition, expert researchers bring the subject up-to-date with key protocols involving the PCR and its many various incarnations such as SSCP, CSGE, and dHPLC. The volume also addresses key areas such as Southern blotting, accurate diagnostics with high throughput, as well as microarray systems. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which provide the often hard to find information that may mean the difference between the success and failure of the method. Authoritative and cutting-edge, PCR Mutation Detection Protocols, Second Edition aims to stimulate postgraduate scientists, researchers, and clinicians already engaged in the area and to provide an important first step for those new to this practice wanting to adopt the powerful and essential technique in their own laboratories.
PCR Primer Design
by Anton YuryevAt the heart of most high-throughput methods is the technique of polymerase chain reaction (PCR). This book focuses on primer design, which is critical to both the efficiency and the accuracy of the PCR. With intricate descriptions of basic approaches as well as specialized methods, "PCR Primer Design" is an exceptional reference for all those involved in studying the genome.
PCR Primer Design (Methods in Molecular Biology #2392)
by Chhandak BasuThis third edition provides new and updated chapters on design PCR primers for successful DNA amplification. Chapters are divided into seven parts, including primer design strategies for quantitative PCR, genotyping, multiplex PCR, in silico PCR primer design, and primer design to identify plant and animal viruses. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, PCR Primer Design, Third Edition aims to be useful for various fields of molecular biology, including biotechnology, molecular genetics, and recombinant DNA technology.
PCR Protocols
by Daniel J. ParkKnown for flexibility and robustness, PCR techniques continue to improve through numerous developments, including the identification of thermostable DNA polymerases which exhibit a range of properties to suit given applications. PCR Protocols, Third Edition selects recently developed tools and tricks, contributed by field-leading authors, for the significant value that they add to more generally established methods. Along with the cutting-edge methodologies, this volume describes many core applications, such as PCR cloning and sequencing, expression, copy number or methylation profile analysis, 'DNA fingerprinting', diagnostics, protein engineering, interaction screening as well as a chapter highlighting workflow considerations and contamination control, crucial for all PCR methods. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary reagents and materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, PCR Protocols, Third Edition seeks to further elucidate this essential technique while also providing core principles with broad applications for scientists of all backgrounds.
PCR Protocols in Molecular Toxicology (Methods in Life Sciences - Toxicology Section)
by John P. Vanden HeuvelMolecular toxicology is an emerging discipline that utilizes molecular and cell biology to understand how drugs and chemicals result in their unwanted effects. PCR Protocols in Molecular Toxicology is a practical guide to the use of polymerase chain reaction (PCR) to help examine, on a molecular and cellular level, how toxic responses are manifested. It offers a basic understanding of PCR and its optimization, as well as describing specific, high-impact areas of molecular toxicology and recent advances. The following techniques are described in detail: Quantitative reverse transcriptase PCR and methods to examine gene expression Differential display cloning Cloning and library screening by PCR Genotype and polymorphism analysis of drug and toxicant metabolizing enzymes Basic, non-PCR based molecular biology methods PCR Protocols in Molecular Toxicology will aid both novices and experienced PCR practitioners in using PCR to its fullest potential.
PCR Technology: Current Innovations, Third Edition
by Stephen A. Bustin Tania NolanPCR's simplicity as a molecular technique is, in some ways, responsible for the huge amount of innovation that surrounds it, as researchers continually think of new ways to tweak, adapt, and re-formulate concepts and applications. PCR Technology: Current Innovations, Third Edition is a collection of novel methods, insights, and points of view that