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PHEs, Environment and Human Health
by Claudio Bini Jaume BechThis book is dedicated to the occurrence and behaviour of PHEs in the different compartments of the environment, with special reference to soil. Current studies of PHEs in ecosystems have indicated that many industrial areas near urban agglomerates, abandoned or active mines, major road systems and ultimately also agricultural land act as sources and at the same time sinks, of PHEs and large amounts of metals are recycled or dispersed in the environment, posing severe concerns to human health. Thanks to the collaboration of numerous colleagues, the book outlines the state of art in PHEs research in several countries and is enforced with case studies and enriched with new data, not published elsewhere. The book will provide to Stakeholders (both Scientists Professionals and Public Administrators) and also to non-specialists a lot of data on the concentrations of metals in soils and the environment and the critical levels so far established, in the perspective to improve the environmental quality and the human safety.
PHTHALATES AND CUMULATIVE RISK ASSESSMENT: The Tasks Ahead
by National Research Council of the National AcademiesPeople are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
PI3K and AKT Isoforms in Immunity: Mechanisms and Therapeutic Opportunities (Current Topics in Microbiology and Immunology #436)
by Margarita Dominguez-VillarThis book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease.PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration and cell death. Recent work has highlighted the multiple roles of PI3K classes and subunits and their involvement in the immune response to the body’s own and foreign antigens and diseases such as cancer and autoimmunity. This book offers a detailed introduction to the biology of the three PI3K classes, followed by an extensive discussion of the diverse roles of AKT and PI3K isoforms in immune cells. Based on this knowledge, it subsequently explains in more detail how specific isoforms are connected to immune-mediated diseases. The book concludes by highlighting the latest advances in the production of isoform-specific inhibitors and their use in various human diseases. This book is intended as a reference guide for students and researchers interested in the multifaceted aspects of PI3K biology.
PI3K-mTOR in Cancer and Cancer Therapy
by Nandini Dey Pradip De Brian Leyland-JonesIn the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority of solid tumors is sustained via the PI3K-AKT-mTOR pathway. Because of its prominent role in many cancer types, the PI3K-mTOR pathway has become a major therapeutic target. The volume includes two complementary parts which address the problem of etiology and disease progression and is intended to portray the very basic mechanisms of the PI3K-AKT-mTOR signaling pathway's involvement in various facets of the cancer, including stem cell renewal, cell metabolism, angiogenesis, genetic instability, and drug resistance. Significant progress has been made in recent years elucidating the molecular mechanism of cancer cell proliferation, angiogenesis, and drug-resistance in relation to the PI3K-mTOR pathway and this volume provides an in-depth overview of recent developments made in this area.
PIP Joint Fracture Dislocations
by Julie E. AdamsComprised exclusively of clinical cases covering injuries to the proximal interphalangeal (PIP) joint, this concise, practical casebook will provide orthopedic surgeons and hand surgeons with the best real-world strategies to properly manage the multifaceted surgical techniques for management of the PIP. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome and clinical pearls and pitfalls. Cases included illustrate both operative and non-operative treatment of volar fracture dislocations, dorsal block splinting and pinning, ORIF with screw fixation, volar plate and hemi hamate arthroplasty, PIP joint fusion, and pediatric PIP joint injuries, among others. Pragmatic and reader-friendly, PIP Joint Fracture Dislocations: A Clinical Casebook will be an excellent resource for orthopedic surgeons and Hand surgeons confronted with both common and complex fractures to the PIP joint.
PJ und Famulatur im Ausland (Springer-Lehrbuch)
by Maximilian Storz Sven GottschlingSie sind Medizinstudent und wollen Ihre Famulatur oder ein PJ-Tertial im Ausland absolvieren? Dann werden Sie bald auf eine Menge offener Fragen stoßen: Wohin soll es gehen? Wie und wann bewerbe ich mich? Mit welchen Kosten muss ich rechnen? Antworten auf diese und noch viele weitere Fragen finden Sie in diesem Buch. Knapp und übersichtlich ist alles enthalten, was man vor und nach der Abreise wissen muss: · Schritt für Schritt durch die Organisation des Auslandspraktikums · Überblick über die beliebtesten Länder · Tipps zum Klinikalltag · Hinweise zu kulturellen Aspekten · Checklisten und Vorlagen · Erfahrungsberichte · Fragen und Antworten am Ende der wichtigsten Kapitel Endlich kommt Licht in den Informationsdschungel und man muss sich die notwendigen Details nicht mehr mühsam zusammensuchen! Der Autor Dr. Maximilian Storz ist Assistenzarzt für Innere Medizin und lebt zur Zeit in Tübingen. Schon während diverser Auslandsaufenthalte in seiner Studienzeit (u. a. Südkorea, Dänemark und Schweiz) hat er intensiv an seinem Buch zum Thema Famulatur und praktisches Jahr im Ausland geschrieben.
PLAB: 1000 Extended Matching Questions
by Una F CoalesThis book is an essential purchase for all candidates sitting Part 1 of the PLAB exam administered by the UK General Medical Council. All doctors from non-EC countries who wish to practice in UK must sit the PLAB exam which comprises 200 Extended Matching Questions (EMQs). This book contains 1000 practice EMQs of a similar type to those in the exam.The questions cover all aspects of the new syllabus, which not only includes a range of clinical topics but also requires knowledge of the GMC's Duties of a Doctor, principles and practice of evidence-based medicine, and clinical governance. Recommended to all candidates sitting the new PLAB test.
PNF in der Praxis: Eine Anleitung in Bildern (Rehabilitation Und Prävention Ser. #22)
by Dominiek Beckers Math BuckVon neurophysiologischen Grundlagen über Befunderhebung und Behandlungstechniken bis hin zu PNF-Pattern – Lernen Sie mit diesem Praxis- und Lehrbuch Schritt für Schritt alle Facetten der Propriozeptiven Neuromuskulären Fazilitation kennen und werden Sie zum Experten dieser etablierten Methode.In diesem Buch finden Sie: Grundlagen der PNF (inklusive PNF-Philosophie, ICF-Modell, motorisches Lernen u.v.m.), PNF-Patterns und ihre funktionelle Anwendung präzise und verständlich erklärt, über 640 farbige Abbildungen für die anschauliche Darstellung aller wichtigen Techniken und Behandlungsschritte, Behandlungsbeispiele und zahlreiche Praxistipps für eine unkomplizierte Umsetzung im therapeutischen Alltag, Fragen am Ende jedes Kapitels zur Kontrolle Ihres LernerfolgsNeu in der 8. Auflage: Vollständig aktualisiert, Vorstellung der Internationalen PNF Association, zusätzliche Anwendungsmöglichkeiten und Patientenbeispiele Ein Muss für alle, die PNF lernen möchten oder bereits anwenden!
POCUS in Critical Care, Anesthesia and Emergency Medicine
by Noreddine Bouarroudj Peňafrancia C. Cano Shahridan bin Mohd Fathil Habiba HemamidThis book describes Emergency Ultrasound (EFAST echo, Lung Ultrasound, Vascular Ultrasound and Transthoracic Echocardiograhy) and all ultrasound technics in Anesthesia practice, i.e. Gastric Ultrasound, Airway Ultrasound and Ultrasound guided vascular access.The book is divided into 11 sections and each section is devoted to a well-defined topic that are further investigated in the dedicated chapters richly and fully illustrated with colored and detailed sonoanatomy drawings. The volume represents a very useful, practical and highly didactic tool.It presents concise up-to-date and evidence-based knowledge in POCUS and explains the use and benefits of ultrasound for intensivists, anesthesiologists, emergency specialists and allied professionals, as well.
POP - PraxisOrientierte Pflegediagnostik
by Elisabeth Jedelsky Dagmar Tomacek Renate Hansmann Ruza Pandzic Franz Allmer Josef Eberl Harald Stefan Kurt Schalek Marie Christine VencourPraxisOrientierte Pflegediagnostik steht für ressourcenorientiertes Diagnostizieren. Dabei werden Potenziale, Risiken und Defizite von Patienten gleichermaßen berücksichtigt. Die Autoren stellen in dem Band über 150 Pflegediagnosen vor: mit klaren Definitionen, konkreten Ressourcen sowie pflegerelevanten Ätiologien und Risikofaktoren. Für die 2. Auflage wurden Erfahrungen mit der Erstauflage eingearbeitet, neue Pflegephänomene aufgenommen und Diagnosen ergänzt. Mit beiliegender CD-ROM und pflegediagnoseorientiertem Anamnesebogen als Hilfsmittel.
POP - PraxisOrientierte Pflegediagnostik: Pflegediagnosen, Ziele und Maßnahmen nach der Version POP2
by Elisabeth Jedelsky Dagmar Tomacek Renate Hansmann Ruza Pandzic Franz Allmer Josef Eberl Harald Stefan Kurt Schalek Marie Christine VencourPraxisOrientierte Pflegediagnostik steht für ressourcenorientiertes Diagnostizieren. Dabei werden Potenziale, Risiken und Defizite von Patienten gleichermaßen berücksichtigt. Die Autoren stellen in dem Band über 150 Pflegediagnosen vor: mit klaren Definitionen, konkreten Ressourcen sowie pflegerelevanten Ätiologien und Risikofaktoren. Für die 2. Auflage wurden Erfahrungen mit der Erstauflage eingearbeitet, neue Pflegephänomene aufgenommen und Diagnosen ergänzt. Mit beiliegender CD-ROM und pflegediagnoseorientiertem Anamnesebogen als Hilfsmittel.
POTS and Other Acquired Dysautonomia in Children and Adolescents: Diagnosis, Interventions, and Multi-disciplinary Management
by Kelly Mccracken Barnhill Fletcher BarnhillThis is an authoritative overview for anyone encountering Postural Orthostatic Tachycardia Syndrome (POTS) - a dysfunction of the autonomic nervous system resulting in diverse symptoms experienced in an upright position that are relieved by lying down - and other types of acquired dysautonomia. It provides essential information on the symptoms, diagnosis and treatment in children and young people. Post-viral syndromes can be extremely difficult to manage and the average individual spends two to three years accessing appropriate diagnosis. This book provides necessary information for parents and healthcare professionals on identifying POTS and other post-viral dysautonomia, the most common triggers, appropriate intervention and successful multi-disciplinary management in both short and long term situations. It also includes helpful tips and coping strategies for managing the syndrome at home and in educational and clinical settings.
PPG Signal Analysis: An Introduction Using MATLAB®
by Mohamed ElgendiThis book serves as a current resource for Photoplethysmogram (PPG) signal analysis using MATLAB®. This technology is critical in the evaluation of medical and diagnostic data utilized in mobile devices. Information and methodologies outlined in the text can be used to learn the empirical and experimental process (including data collection, data analysis, feature extractions, and more) from inception to conclusion. This book also discusses how introduced methodologies can be used and applied as tools that will teach the user how to validate, test, and simulate developed algorithms before implementing and deploying the algorithms on wearable, battery-driven, or point-of-care devices.
PR und Organisationskommunikation im Gesundheitswesen: Interdisziplinäre Perspektiven auf Wertehorizonte und deren Spannungsfelder
by Doreen ReifegersteDas Gesundheitssystem ist geprägt von medizinischen, gemeinwohlorientierten und ökonomischen Interessen. Diese Zielgrößen sind dabei vor dem Hintergrund gesellschaftlicher und systembezogener Wandlungsprozesse wie der Patientenorientierung und Digitalisierung zu bewerten. In der Gesamtschau ergibt dies ein Spannungsfeld konkurrierender und komplementärer Ziele in der internen und externen Kommunikation von Kliniken, Pharmaunternehmen, Krankenversicherungen und einzelner Akteure des Gesundheitswesens. Auf dieses Spannungsfeld geht dieser Band ein und integriert dabei die Perspektiven der PR-und Organisationskommunikation sowie der Gesundheitskommunikation.
PREPAREDNESS NOW!
by Aton EdwardsIn uncertain times, a solid preparedness plan is essential for every individual and family. PREPAREDNESS NOW! navigates the new realities of twenty-first century living: extreme weather, economic instability, terror attacks, and more.Packed with checklists, resources, and step-by-step instructions, PREPAREDNESS NOW! details everything needed for office, car, and home preparedness. This newly expanded and revised edition includes an extended chapter on food and water storage and urban gardening, techniques in personal defense, and the latest and best preparedness products on the market. This book encourages basic lifestyle changes that lead to a more self-sufficient and satisfying existence, regardless of circumstance.PREPAREDNESS NOW! is written by one of the most experienced preparedness experts in the field. Aton Edwards is executive director of the International Preparedness Network (IPN) and has worked with the Red Cross, NYPD, Center for Disease Control, and thousands of people domestically and overseas.This manual delivers practical advice on: Building your emergency kits for home, car, and office Water quality control and storage Emergency shelter, power, lighting, and heating Emergency transportation, communications, and evacuation Extreme weather preparedness Chemical, biowarfare, and nuclear preparedness Defense against infectious diseases Personal defense and crime prevention for the twenty-first century home
PRK: Past, Present, and Future
by Lucio Buratto Steven G. Slade Sebastiano Serrao Marco LombardoModern laser vision correction has continually changed since its inception. The evolution of this procedure has been aided by broad technological advancements, increased surgical knowledge, and increased understanding of the cornea and its response to lasers.PRK: The Past, Present, and Future of Surface Ablation will provide a complete vision of the PRK laser correction techniques that have emerged and the technological advancements that have made them possible. The collaboration of Drs. Buratto, Slade, Serrao, and Lombardo, along with a team of international surgeons have produced a complete book specifically designed to assist clinician’s to improve the quality of their patient’s visionWith over 85 color illustrations demonstrating the various procedures and concepts, the book will help ophthalmologists develop a more thorough understanding of PRK. PRK: The Past, Present, and Future of Surface Ablation is excellent for surgeons interested in learning the concepts, developing skills, and preparing for the actual laser procedure. This definitive resource couples both the authors' and 9 contributors' diverse experience and knowledge to produce a complete vision of PRK laser vision correction. PRK: The Past, Present, and Future of Surface Ablation will be the definitive resource necessary for all surgeons aspiring to improve their surgical results using the latest techniques available.
PROLOG: Assessment And Critique (Prolog)
by American College of Obstetricians and GynecologistsEach of the 6 units of PROLOG addresses a major area in obstetrics and gynecology and consists of two parts—an assessment book and a critique book. Put your knowledge to the test and earn 25 CME credits for this volume! The obstetrician–gynecologist who completes Obstetrics, Eighth Edition, should be able to:Demonstrate an understanding of maternal and fetal physiology and pathophysiology and their impact on normal and complicated pregnanciesIdentify components of antepartum care that optimize maternal and perinatal outcomes in uncomplicated pregnancies, including education regarding normal pregnancyDiagnose and plan efficacious and cost-effective management of medical and obstetric conditions encountered during the antepartum period.Identify the risks and prognosis of selected complications of pregnancy and in the neonateDescribe invasive and noninvasive methods of fetal assessment in the antepartum period and identify the risks, indications, predictive value, and physiologic basis for testsDiagnose problems and manage obstetric emergencies.Select appropriate management strategies for intrapartum care and deliveryConsider medical-legal principles, risk management and office management guidelines in obstetric practice.
PROLOG: Obstetrics, Ninth Edition (Prolog)
by American College of Obstetricians & Gynecologists College of AmericanPROLOG: Obstetrics is the premier learning tool for staying up to date in the specialty area. Consisting of an assessment and critique book, PROLOG is an effective, self-directed study resource and reference for both obstetricians– gynecologists and those in training. The content is peer-reviewed, current, and clinically relevant. Put your knowledge to the test and earn up to 25 CME credits with this volume.Upon successful completion, users of this unit will be able to:Demonstrate an understanding of maternal and fetal physiology and pathophysiology and the effects on normal and complicated pregnanciesIdentify components of antepartum care that optimize maternal and perinatal outcomes in uncomplicated pregnancies, including education regarding normal pregnancyDiagnose and plan efficacious and cost-effective management of medical and obstetric conditions encountered during the antepartum periodIdentify the risks and prognosis of selected complications of pregnancy and in the neonateDescribe antenatal genetic screening and diagnostic tests and identify the indications, risks, and predictive value for eachDiagnose problems and manage obstetric emergenciesSelect appropriate management strategies for intrapartum care and deliveryConsider medical-legal principles, risk management, and office management guidelines in obstetric practiceOrder PROLOG: Obstetrics, Ninth Edition, today!A complimentary, online study tool— PROLOG Games— is included with purchase of this print copy.
PROLOG: Patient Management in the Office, Eighth Edition (Prolog)
by American College of Obstetricians and GynecologistsPROLOG: Patient Management in the Office, Eighth Edition, is the premier learning tool for staying up-to-date in obstetrics and gynecology. Consisting of an assessment and critique book, PROLOG is an effective, self-directed study resource and reference for both obstetrician–gynecologists and those in training. The content is peer-reviewed, current, and clinically relevant. Put your knowledge to the test and earn 25 CME credits with this volume.
PROLOG: Reproductive Endocrinology and Infertility, Ninth Edition (Prolog)
by American College of Obstetricians & GynecologistsPROLOG: Reproductive Endocrinology and Infertility, Ninth Edition, is the premier resource for staying up to date in this specialty area. Consisting of critique and assessment sections, PROLOG offers an effective, self-directed study experience for obstetrician–gynecologists and those in training. The content is current, relevant, and written and reviewed by experts in the field. Put your knowledge to the test and earn 25 CME credits with this volume. Upon completing this unit, learners should be able to: • Identify appropriate tests for endocrinology and infertility conditions. • Determine the appropriate medical management to address infertility. • Apply the concepts of the hypothalamic-pituitary-ovarian-uterine axis when considering medication. • Understand the basics of assisted reproductive technology. • Counsel women regarding treatment options for primary and secondary amenorrhea and infertility. Purchase PROLOG: Reproductive Endocrinology and Infertility, Ninth Edition, today to advance your knowledge and enhance your practice. A complimentary, online study tool, PROLOG Games, is included with purchase of the printed book.
PROPEL to Quality Healthcare: Six Steps to Improve Patient Care, Staff Engagement, and the Bottom Line
by Thomas M Muha Martha MurphyYou got into healthcare because you wanted to help people, but quickly discovered providing high-quality care is challenging. Seemingly impossible demands are placed on you and your team. Some coworkers are constantly complaining; others are in their silos doing only what they must to get through the long days. Collaboration is often lacking, and patients suffer the painful consequences. It’s easy to become overloaded with work and overwhelmed with negativity. This is not how the healthcare profession has to be. There is a new science – Positive Psychology – that studies how people are able to perform extraordinarily well in challenging situations. After a dozen years of research in prestigious medical centers, an evidence-based method for applying this science has been developed. That six step program is PROPEL. You will read stories illustrating the experiences of doctors, nurses and administrators who learned to use PROPEL to transform their professional life (and, for many, their personal life as well). You will learn how they were able to attain remarkable results with their teams, units and clinics: • Staff callout and FMLA decreased 75% • Wait times for chemotherapy infusion reduced 6 hours • Staff turnover dropped 80% • Pediatric MRI scheduling driven down from 14 weeks to 10 days • Bone marrow transplant procedures increased by 50% • ED diversion due to psychiatric patient boarding virtually eliminated • Patient fall rate cut by 70% • Use of agency and travelers nurses abolished • Patient satisfaction scores up 50% The cumulative impact to the bottom line has been calculated to be millions of dollars. The most meaningful measure of PROPEL’s success, however, comes from the thousands of dedicated professionals who have expressed heartfelt gratitude for having learned how to recapture their joy for working in healthcare.
PROTAC-Mediated Protein Degradation: A Paradigm Shift in Cancer Therapeutics
by Mukesh Nandave Priti JainThis book is a comprehensive coverage of the ubiquitin-proteasome system and its involvement in cancer progression, and the application of PROTACs in different types of cancer treatment. The book discusses a unique perspective and comprehensive knowledge of the potential of PROTACs to transform cancer therapies. It provides an overview of the history, mechanisms, chemistry, design considerations, and different technologies involved in PROTACs. Additionally, it explains the ubiquitin-proteasome system, its impact on various diseases, and the principles and mechanisms of UPS. The book also describes the chemistry and design aspects of PROTACs and their role in various types of cancers. Finally, it covers the pharmaceutics aspect of formulation design, global requirements, and toxicological aspects of PROTACs. This book is targeted at cancer researchers, medical oncologists, bioinformatics, computational biologists, pharmacologists, medicinal chemists, formulation scientists, regulatory authorities, and policy makers.
PTAEXAM: The Complete Study Guide
by Scott M. Giles"Perhaps the most valuable piece of Information a candidate can utilize when preparing for the National Physical Therapist Assistant Examination is the National Physical Therapist Assistant Examination Blueprint. The blueprint provides a detailed analysis of each of the content areas of the National Physical Therapist Assistant Examination. A thorough understanding of the content outline and system specific weighting will streamline a candidate's preparation. Less time will be spent covering topics that are not clinically relevant to the actual examination and as a result, more time will be available for reviewing and relearning. Perhaps the most valuable piece of Information a candidate can utilize when preparing for the National Physical Therapist Assistant Examination is the National Physical Therapist Assistant Examination Blueprint. The blueprint provides a detailed analysis of each of the content areas of the National Physical Therapist Assistant Examination. A thorough understanding of the content outline and system specific weighting will streamline a candidate's preparation. Less time will be spent covering topics that are not clinically relevant to the actual examination and as a result, more time will be available for reviewing and relearning.
PTAEXAM: The Complete Study Guide
by Scott M. GilesScorebuilders compete study guide to the PTA Exam- by Scott M. Giles. -Comprehensive academic review -Hundreds of new challenging questions -Three online full length exams - Explanations of correct and incorrect answers - Sophisticated performance analysis
PTCE - Pharmacy Technician Certification Exam Flashcard Book + Online
by Della Ata KhouryPTCE (Pharmacy Technician Certification Exam) Flashcard Book400 Questions & Answers You Need to KnowWritten by a seasoned pharmacy technician instructor, this PTCE study supplement covers everything you need to know for the exam: assisting the pharmacist in serving patients, maintaining medication and inventory control systems, and participating in the management of pharmacy practice.The 400 flashcards are broken down by PTCE test topics and include multiple-choice questions with detailed answers. We give you:100 flashcards focused on the top 100 brand/generic drug names including their drug classes, indications, side effects, and special considerations; 50 flashcards focused on pharmaceutical terms and abbreviations and 250 flashcards focused on PTCE review material: Assisting the Pharmacist in Serving Patients (165 flashcards), Maintaining Medication and Inventory Control Systems (50 flashcards), and Participating in the Administration and Management of Pharmacy Practice (30 flashcards).After studying with the book, review what you've learned at REA's online Study Center. Customizable e-flashcards and 3 practice quizzes let you create your own PTCE study plan and study anywhere, anytime. You can also make your own flashcards for any topics that give you difficulty.If you're a pharmacy tech student and want extra practice and review before the exam, REA's PTCE Flashcard Book is the right Rx for your study needs.