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Ano-Rectal Endosonography and Manometry in Paediatrics

This book brings together lessons learned in the clinical use of anorectal endosonography and manometry in paediatrics. In contrast to adult medicine, where they are virtually indispensable for specialists dealing with colo-proctology, in paediatrics endoanal ultrasound and anorectal manometry are still the prerogative of very few international centres. This book collects the results of a Workshop organised at the Paediatric Surgery Unit of Bologna, entitled "International Seminar on Endosonography and Anorectal Manometry in Paediatrics", and presents contributions from leading European experts. Focusing on the paediatric age group, this volume fills a gap in the paediatric gastroenterology literature, and will benefit all specialists wishing to use these methods in the management and treatment of common clinical problems, e.g. chronic constipation.

Anogenitale Hautkrankheiten: Erkennen, Befunden, Behandeln

Blickdiagnose für Hausärzte, Urologen, Gynäkologen und Dermatologen Blickdiagnose für Hausärzte, Urologen, Gynäkologen und Dermatologen! Hautkrankheiten im Bereich des männlichen und weiblichen Genitale werden durch die Eigenheiten der Genitalregion modifiziert. Eine Re ihe davon manifestiert sich aber auch nur im Genitalbereich. Diese werden oft erstmals von einem Facharzt beobachtet, der sich mit anderen genitalen Beschwerden beschäftigt, etwa der Urologe bei Männern oder der Gynäkologe bei Frauen. Dieses Buch möchte gerade den Nicht-Dermatologen einige Krankheitsbilder demonstrieren, die sie im Genitalbereich zu sehen bekommen und sie auf die nosologische Bedeutung und die Parallelen zu anderen Hautkrankheiten hinweisen und den Blick des befundenen Arztes schulen. Das Buch umfasst das Wichtigste für den behandelnden Arzt: - von der Blickdiagnose zur Therapie - über 150 farbige Abbildungen zum Erkennen und Wiedererkennen der Pathologien - kurze Texte zum schnellen Erfassen der Symptomatik und Therapieoptionen Ein unverzichtbarer Begleiter für Praxis und Klinik!

Anoikis: How the Extracellular Matrix Regulates Life-or-Death Decisions

Anoikis is defined broadly as apoptosis that is inhibited by appropriate cell-matrix interactions. Normal and tumor cells vary widely in their sensitivity to anoikis, but, in general, metastatic tumor cells are inevitably anoikis-resistant. In particular, tumor cells that possess a cancer stem cell or mesenchymal phenotype, arising from the oncogenic Epithelial-Mesenchymal Transition (EMT), are transcriptionally re-programmed to resist anoikis. While the anoikis response occurs through the mitochondrial pathway typically found in other apoptotic responses (e.g., DNA damage, death receptors, oxidative stress), the regulation of anoikis by cell-matrix signalling is unique and only partially characterized. The uniqueness of anoikis is: a. regulation by integrins, non-integrin matrix receptors, and the signaling complexes associated with them; b. regulation by metabolic changes occurring in response to attachment/detachment; c. regulation by oncogenes and tumor suppressor genes d. regulation by tumor microenvironment; e. regulation by EMT.

Anomalies and Curiosities of Medicine

Anomalies of the Developing Dentition: A Clinical Guide To Diagnosis And Management

This book is an up-to-date, succinct, and easily accessible reference on the diverse anomalies that may arise in the developing dentition, including those relating to crown size and shape, tooth formation, tooth eruption, tooth number, and enamel and dentin formation. For each anomaly, information is provided on clinical and radiographic features, etiology, and management. Attention is also drawn to clinically relevant associations among anomalies. The inclusion of numerous high-quality photographs and images will assist the practitioner in establishing the correct diagnosis in each patient and in understanding the rationale for specific interventions. The book will also facilitate discussion of the anomaly with the caregiver or patient, including with respect to genetic and other implications and the appropriate treatment path. Anomalies of the Developing Dentition is an excellent clinical guide to the subject that will aid in timely identification and appropriate management. It will meet the needs of students and practitioners in multiple disciplines of both medicine and dentistry.

Anomia: Theoretical and Clinical Aspects (Brain, Behaviour and Cognition)

This important book provides a broad, integrated overview of current research on word-finding deficit, anomia, the most common symptom of language dysfunction occurring after brain damage. Besides its clinical importance, anomia gives a fascinating view on the inner workings of language in the brain. Written by two internationally known researchers in the field, the book begins with an overview of psycholinguistic research on normal word retrieval as well as the influential cognitive models of naming and goes on to review the major forms of anomia. Neuroanatomical aspects, clinical assessment and therapeutic approaches are reviewed and evaluated. This edition has been fully updated to include coverage of advances in cognitive modeling of lexical retrieval disorders, structural and functional neuroimaging findings on the neural basis of naming and anomia, anomia diagnostics and new approaches to the challenging task of anomia therapy. Covering both theory and practice, this book provides invaluable reading for researchers and practitioners in speech and language disorders, neuropsychology and neurology, as well as for advanced undergraduate students and graduate students in the field.

Anophthalmia: The Expert's Guide to Medical and Surgical Management

This book provides a comprehensive review on the surgical care of patients requiring removal of an eye, as well as consequent functional and cosmetic rehabilitation. In addition to covering the crafting of ocular prosthetics, Anophthalmia: The Expert's Guide to Medical and Surgical Management also addresses the psychological and physical adjustments to losing an eye, and adapting to that loss.Divided into five parts, Anophthalmia functions as a go-to reference for ophthalmologists and oculoplastic surgeons. The book begins by laying out the clinical foundations and history of anophthalmia. Part II and III discuss surgical removal techniques, prosthesis fitting and maintenance, congenital anophthalmia, infections and inflammations, and newer surgical techniques such as osseointegration after orbital exenteration. Finally, the book concludes with chapters on prosthetic options including scleral shells, keratopigmentation procedures, and cosmetic contact lenses.Unique in content, Anophthalmia is a vital resource for practicing ophthalmologists, oculoplastic surgeons, and all medical professionals who care for patients with surgical and traumatic loss of the eye and orbital tissues. Additionally, sufficient detail and explanation make this work accessible to those in training, such as medical students, ophthalmology residents, and fellows.

Anorectal Disease: Contemporary Management

This book provides a concise yet comprehensive summary of the current status of the field that guides patient management and stimulate investigative efforts. It is an easy reference for day-to-day anorectal pathology. The text reviews new testing procedures for anorectal diseases and provides new treatment options about anorectal disease both benign and malignant. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. The text includes highly practical presentations of typical patients seen in the clinical practice of proctology in the form of case presentations with expert analysis and commentary. Example cases would include common but challenging cases such as an anal tumor, chronic anal pain and anal discharge. Anorectal Disease: Contemporary Management is a comprehensive, state-of-the-art review of this field and serves as a valuable resource for residents, clinicians, surgeons and researchers with an interest anorectal disease.

Anorectal Physiology: A Clinical and Surgical Perspective

This is the first comprehensive book exclusively dedicated to anorectal physiology and the importance of diagnostic tools in guiding the evaluation and treatment of anorectal dysfunction. Functional disorders, and specifically fecal incontinence and evacuatory disorders, are prevalent in the general population, affecting up to 20% of individuals. As many of these conditions have extremely complex mechanisms, a thorough understanding of anorectal physiology is a crucial element in the surgeon’s “arsenal" to ensure accurate evaluation and to inform treatment. At this time, there is no other title that specifically addresses all aspects of anorectal physiology, as well as anorectal and pelvic floor disorders, including fecal incontinence and defecation disorders. Specifically, the book provides detailed descriptions of diagnostic methods and treatment algorithms for a range of anorectal conditions, including modern treatment modalities such as sacral neuromodulation.A unique and comprehensive reference covering all aspects of the evaluation and treatment of anorectal disorders, Anorectal Physiology – A Clinical and Surgical Perspective will be of significant interest to proctologists and coloproctologists, gastroenterologists, colorectal surgeons, gynecologists and all other professionals interested in anorectal physiology.

Anorexia Nervosa and Recovery: A Hunger for Meaning

Through the voices of twenty-one women, Karen Way presents the most objective, complete, and compassionate picture of what anorexia nervosa is about and, more importantly, of the complex individual variables and obstacles in the journey to recovery. From the premise that anorexia nervosa is an addiction--an obsession controlling all aspects of an individual’s life--and that complete recovery is possible by finding meaning in life, this enlightening book contrasts sharply to other books written on the subject by clinicians and theorists which merely speculate on the nature and etiology of anorexia nervosa. Anorexia Nervosa and Recovery lets the reader hear the personal struggles of women who have fought this powerful disease. They describe how anorexia controlled their lives and how, once they overcame their obsessions with food, weight, and thinness, they were able to lead fulfilling lives. This illuminating book encourages and inspires women who are in the throes of anorexia nervosa. They will recognize the emptiness in the voices and the descriptions of daily life. Therapists and clinicians who treat anorexic women will find intriguing chapters on events which trigger anorexia and what anorexics will do to maintain their strategies for coping. Concerned friends and family and others interested in understanding this controlling disease will be enlightened from this important and helpful book.

Anorexic Bodies: A Feminist and Sociological Perspective on Anorexia Nervosa

This book explores the ways in which anorexic women use their eating to control their bodies. It argues that the female body in modern Western culture is understood as open and accessible and female appetite as dangerous and voracious. Anorexia attempts to resist both these constructions in the creation of a closed, desireless body. Since anorexic women resist the power of collective ideologies their resistance cannot work - the closed body becomes its own prison.

Another Day in the Frontal Lobe: A Brain Surgeon Exposes Life on the Inside

Katrina is a neurosurgeon, one of only two hundred or so women among the alpha males who dominate this high-pressure, high-prestige medical specialty. She is also a superbly gifted writer witty, insightful, at once deeply humane and refreshingly wry.

Another Day in the Frontal Lobe: A Brain Surgeon Exposes Life on the Inside

Katrina Firlik is a neurosurgeon, one of only two hundred or so women among the alpha males who dominate this high-pressure, high-prestige medical specialty. She is also a superbly gifted writer–witty, insightful, at once deeply humane and refreshingly wry. In Another Day in the Frontal Lobe, Dr. Firlik draws on this rare combination to create a neurosurgeon’s Kitchen Confidential–a unique insider’s memoir of a fascinating profession.Neurosurgeons are renowned for their big egos and aggressive self-confidence, and Dr. Firlik confirms that timidity is indeed rare in the field. “They’re the kids who never lost at musical chairs,” she writes. A brain surgeon is not only a highly trained scientist and clinician but also a mechanic who of necessity develops an intimate, hands-on familiarity with the gray matter inside our skulls. It’s the balance between cutting-edge medical technology and manual dexterity, between instinct and expertise, that Firlik finds so appealing–and so difficult to master. Firlik recounts how her background as a surgeon’s daughter with a strong stomach and a keen interest in the brain led her to this rarefied specialty, and she describes her challenging, atypical trek from medical student to fully qualified surgeon. Among Firlik’s more memorable cases: a young roofer who walked into the hospital with a three-inch-long barbed nail driven into his forehead, the result of an accident with his partner’s nail gun, and a sweet little seven-year-old boy whose untreated earache had become a raging, potentially fatal infection of the brain lining. From OR theatrics to thorny ethical questions, from the surprisingly primitive tools in a neurosurgeon’s kit to glimpses of future techniques like the “brain lift,” Firlik cracks open medicine’s most prestigious and secretive specialty. Candid, smart, clear-eyed, and unfailingly engaging, Another Day in the Frontal Lobe is a mesmerizing behind-the-scenes glimpse into a world of incredible competition and incalculable rewards.From the Hardcover edition.

Another Eyesight: Multi-Sensory Design in Context

This book provides an overview and some in-depth information about the many ways of creating multi-sensory access for blind and partially sighted people to art, nature and historical sites.

Another Kind of Madness: A Journey Through the Stigma and Hope of Mental Illness

WINNER: Best Autobiography/Memoir, 2018 Best Book Awards, sponsored by American Book Fest Glenn Close says: "Another Kind of Madness is one of the best books I’ve read about the cost of stigma and silence in a family touched by mental illness. I was profoundly moved by Stephen Hinshaw’s story, written beautifully, from the inside-out. It’s a masterpiece."A deeply personal memoir calling for an end to the dark shaming of mental illnessFamilies are riddled with untold secrets. But Stephen Hinshaw never imagined that a profound secret was kept under lock and key for 18 years within his family—that his father’s mysterious absences, for months at a time, resulted from serious mental illness and involuntary hospitalizations. From the moment his father revealed the truth, during Hinshaw’s first spring break from college, he knew his life would change forever. Hinshaw calls this revelation his “psychological birth.” After years of experiencing the ups and downs of his father’s illness without knowing it existed, Hinshaw began to piece together the silent, often terrifying history of his father’s life—in great contrast to his father’s presence and love during periods of wellness. This exploration led to larger discoveries about the family saga, to Hinshaw’s correctly diagnosing his father with bipolar disorder, and to his full-fledged career as a clinical and developmental psychologist and professor. In Another Kind of Madness, Hinshaw explores the burden of living in a family “loaded” with mental illness and debunks the stigma behind it. He explains that in today’s society, mental health problems still receive utter castigation—too often resulting in the loss of fundamental rights, including the inability to vote or run for office or automatic relinquishment of child custody. Through a poignant and moving family narrative, interlaced with shocking facts about how America and the world still view mental health conditions well into in the 21st century, Another Kind of Madness is a passionate call to arms regarding the importance of destigmatizing mental illness.

Another Path to My Garden: My Life as a Quadriplegic

Marilyn Noell looks back over the past forty-three years of her life as a quadriplegic. Her struggles have been many – fear, depression, surgery, learning to use what "moving parts" remained after her diving accident when she was just nineteen. But perhaps her toughest challenge has been to be and be seen as a useful, active individual.

Another Person’s Poison: A History of Food Allergy (Arts and Traditions of the Table: Perspectives on Culinary History)

To some, food allergies seem like fabricated cries for attention. To others, they pose a dangerous health threat. Food allergies are bound up with so many personal and ideological concerns that it is difficult to determine what is medical and what is myth. Another Person's Poison parses the political, economic, cultural, and genuine health factors of a phenomenon that dominates our interactions with others and our understanding of ourselves. For most of the twentieth century, food allergies were considered a fad or junk science. While many physicians and clinicians argued that certain foods could cause a range of chronic problems, from asthma and eczema to migraines and hyperactivity, others believed that allergies were psychosomatic. ' <P><P>This book traces the trajectory of this debate and its effect on public-health policy and the production, manufacture, and consumption of food. Are rising allergy rates purely the result of effective lobbying and a booming industry built on self-diagnosis and expensive remedies? Or should physicians become more flexible in their approach to food allergies and more careful in their diagnoses? Exploring the issue from scientific, political, economic, social, and patient-centered perspectives, this book is the first to engage fully with the history of a major modern affliction, illuminating society's troubled relationship with food, disease, nature, and the creation of medical knowledge.

Another Twinkle in the Eye: Contemplating Another Pregnancy After Perinatal Mental Illness

Another Twinkle in the Eye is an essential guide for anyone contemplating another pregnancy after perinatal mental illness. The decision to bring a child into the world is rarely one that is taken lightly. When a previous pregnancy and early parenthood has resulted in poor maternal and/or paternal perinatal mental health, making a conscious decision to have another baby can be even more challenging. This unique book provides facts, resources, and discussion points to support people in making informed and comfortable decisions. It is also an essential resource for health professionals who support or are involved in the decision-making process of couples planning another pregnancy. The author combines personal experience with real-life stories from other parents. Also included are contributions from healthcare professionals. The book offers comprehensive coverage across five key areas: Reflection on the previous pregnancy, miscarriage or stillbirth, Decisions to be made when considering another pregnancy, Ways to plan for and to have a healthier experience, The role of healthcare professionals and facilities, and Self-help and complementary techniques for good mental health in the perinatal period.

Another War, Another Peace: A Novel

The powerful story of an unlikely friendship and a doctor&’s re-education on the battlefields of the Vietnam WarFresh out of medical school and planning to enter academia, David pragmatically applies to serve in the US Army, thinking he would rather work in a stateside military hospital than get drafted. But when he gets reassigned to Southeast Asia, he suddenly finds himself on a base in Vietnam. He joins a civilian aid mission on a supposedly secure plateau, and spends his days dispensing pills to villagers. As David comes to terms with the unexpected factors that brought him to Vietnam, he must adjust to many more twists and turns—among them his relationship with his driver, Tom, a young, rough-hewn Southerner whose reticence feels unnervingly like indifference. Gradually, however, David sees that there&’s far more to Tom than he initially thought. As their friendship grows, David also realizes that his fellow doctors and the troops on base hold widely diverging opinions about the war and its objectives. As it becomes clear that their base is located on a key strategic route—the notorious Ho Chi Minh Trail—and thus a vulnerable target, it&’s only a matter of time before battles break out . . .

Another Way of Looking at Bipolar Disorder

People might call me a miracle man: I am cured from bipolar disorder. I know through experience that these words could surprise people, and many won’t even believe them. That’s one of the difficulties of bipolar disorder: as doctors don’t know how to cure it, they insist on the fact that people can’t be cured and affirm this. This is my true story.

Another Whistle Blower: McGee and Big Pharma Criminals

Another Whistle Blower is the sixth and final novella of Carl Douglass's McGee series. Pharmacist Cecil Edgington strikes it rich when he joins a pharmaceutical consortium to market a cancer wonder drug. Or is it too good to be true? He learns a little more, begins to suspect much more; and finally, he gets downright scared. That is when he seeks to counsel, assistance, and protection of McGee & Associates. McGee uncovers a vast conspiracy, a dangerous cabal, and a labyrinthine source of riches beyond his greatest imaginations. Cecil has a life-altering decision to make: should he stay with the consortium and get rich? Or should he become a whistleblower and live as a fugitive? That decision is the stuff of a riveting book and a life's lesson.

Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems

Succeed in your course with Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, the most comprehensive source on this subject available today!

Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems

The most trusted source on the subject available today, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 12th Edition equips pharmacy students with everything they need to master the intricacies of pharmaceutical dosage form design and production and achieve successful outcomes in their courses and beyond. Reflecting the latest CAPE, APhA, and NAPLEX® competencies, this trusted, extensively updated resource clarifies the interrelationships between pharmaceutical and biopharmaceutical principles, product design, formulation, manufacture, compounding, and the clinical application of the various dosage forms in patient care, as well as regulations and standards governing the manufacturing and compounding of pharmaceuticals. New and revised content throughout keeps students up to date with current approaches to key coverage areas, and additional case studies demonstrate concepts in action to reinforce understanding and prepare students for the clinical challenges ahead.

Ansie di una giovane madre

Questo libro è scritto per i giovani genitori, specialmente per quelli che non hanno ancora esperienza nell'arte della maternità per aiutare ad alleviare le ansie che seguono la nascita e la cura di un neonato fino a un anno di età. Sebbene il titolo sembra focalizzarsi sulle madri, i padri non sono esentati e dovrebbero anche passare in rassegna questo libro dal momento che anche loro sono coinvolti nella preoccupazione e nel trascorrere notti insonni. Si presume che i neonati siano un dono desiderato di Dio e un carico di gioia per i loro genitori, ma spesso nquesta gioia viene stroncata da ansie che risultano dalla mancanza di conoscenza, "vecchie dicerie", miti e credenze culturali che spesso non sono molto corrette, mandando i giovani genitori a correre da un posto all'altro in cerca di soluzioni. Abbastanza divertente, la maggior parte delle cause di preoccupazioni sono spesso processi normali che dovrebbero aver luogo dato che il neonato si riadatta alla vita fuori dal grembo materno. Alcuni sono problemi minori che potrebbero essere risolti da un Pediatra o un buon Professionista Generico spesso tramite counseling, portando un sollievo mlìolto desiderato e un ambiente rilassato in casa. Comunque, un viaggio verso un posto sbagliato o un suggerimento sbagliato da ambienti sbagliati potrebbe, non solo danneggiare in modo permanente il bambino ma anche condurre al decesso del neonato o infante con molto dolore da parte della famiglia. I fatti in questo libro sono raccolti per aiutare questi giovani genitori ad acquisire le conoscenze di cui hanno bisogno per gestire i loro neonati, ridurre l'ansia ed applicare misure appropriate che aiuteranno i neonati a godere di un inizio in salute nella vita. E' il risultato di molti anni di pratica sia nel campo della salute infantile sia nel sistema ospedaliero pubblico e privato. Esso darà una risposta a molte domande poste da giovani madri che consultano pediatri, altri dottori, infe

Ansiedades de uma jovem mãe

Este livro foi desenvolvido para os pais jovens ou de primeira viagem, aqueles que ainda não tiveram alguma experiência na arte da maternidade, para ajudar a aliviar algumas preocupações e ansiedades que vêm junto com o nascimento e os cuidados com um bebê recém-nascido até o primeiro ano de vida. Apesar do título parecer focar nas mães, pais não estão isentos e também devem tomar conhecimento do conteúdo neste exposto, já que eles também estão envolvidos nas preocupações e nas noites em claro. Os bebês devem ser desejados presentes de Deus e trazer muitas alegrias aos seus pais, mas muitas vezes a alegria é incompleta, devido às preocupações resultantes da falta de conhecimento, às crendices, mitos e crenças culturais imprecisas, fazendo com que jovens pais “corram de um lado para o outro” em busca de soluções. É interessante ressaltar que o foco da maioria das preocupações deve acontecer por processos naturais, já que o recém-nascido está se ajustando à nova vida fora do útero da mãe. Em poucos casos há de fato problemas menores que podem ser resolvidos por um bom pediatra ou clínico-geral durante consulta, trazendo alívio e relaxamento ao ambiente do lar. Entretanto, uma ida ao lugar errado ou um conselho de alguém não capacitado, pode não somente provocar algum dano permanente à criança, como também provocar o falecimento do bebê ou da criança, trazendo extrema tristeza à família. O conteúdo deste livro está organizado de maneira a ajudar esses jovens pais a adquirirem conhecimentos necessários nos cuidados de seus bebês, a reduzirem a ansiedade e a aplicarem medidas apropriadas que irão promover um início de vida mais saudável. Este é o resultado de muitos anos de prática em saúde da criança, em redes hospitalares públicas e privadas. Ele irá tirar muitas dúvidas apresentadas por jovens mães nas consultas com pediatras, com outros médicos, com enf