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Reproduktionsimmunologie

by Wolfgang Würfel

Das Buch beschreibt die immunologischen Regulationsmechanismen, angefangen von der Implantation bis hin zur Schwangerschaft in Theorie und Praxis und gibt einen Ausblick zur Immunonkologie. Bisher hat sich die Reproduktionsmedizin stark auf die Herbeiführung der extrakorporalen Fertilisation fokussiert, doch werden Einnistungsprobleme immer evidenter.Expertinnen und Experten auf diesem Gebiet der Reproduktionsmedizin beantworten umfassend Fragen zu Implantationsproblemen, rezidivierenden Aborten, Schwangerschaftskomplikationen und Autoimmunerkrankungen auf der Basis von immunologischen Fehlregulationen.Kennen Sie die wichtigsten Grundlagen zu immunologischen Regulationsmechanismen bei Implantation und Schwangerschaft und deren Auswirkungen auf das immunologische Milieu, dann behandeln Sie Ihre Patientinnen optimal. Das Buch richtet sich an Reproduktionsmediziner, Pränatalmediziner, Geburtshelfer sowie interessierte Onkologen.

Reproduktionsmedizin: Gynäkologie Und Gynäkologische Onkologie, Geburtshilfe, Perinatologie Und Pränatale Diagnostik, Gynäkologische Endokrinologie Und Reproduktionsmedizin (Springer Reference Medizin)

by Michael Ludwig Klaus Diedrich Georg Griesinger

Die Betreuung von Paaren mit Kinderwunsch und ungewollt kinderlosen Paaren erfordert von Gynäkologen und Reproduktionsmedizinern nicht nur Wissen über die menschliche Fortpflanzung, sondern auch die Kenntnis psychosomatischer, gynäkologischer, andrologischer, juristischer und ethischer Aspekte. Die Autoren des Leitfadens und Nachschlagewerks behandeln diese Themen fundiert und praxisnah. Beginnend bei den physiologischen Grundlagen führend sie über die Diagnostik hin zu den verschiedenen reproduktionsmedizinischen Techniken.

Reprogenetics: Law, Policy, and Ethical Issues (Bioethics)

by Gregory E. Kaebnick Lori P. Knowles

From the cloning of Dolly the sheep a decade ago to more recent advances in embryonic stem cell research, new genetic technologies have often spurred polemical, ill-informed debates. Perhaps nowhere is this more evident than in the field of reproductive genetics, where difficult bioethical issues are distilled into sound bites and far-fetched claims for easy public consumption. The underlying complexities of reprogenetic research and practice are often drowned out by the noise.In this thoughtful and informed collection, Lori P. Knowles and Gregory E. Kaebnick bring together bioethicists from the United States, Canada, and the United Kingdom to examine the ethical and policy quandaries created by new genetic technologies. Featuring an overview of the field’s history (including lessons to be learned from eugenics), comparisons of international and domestic governmental regulations, and discussions of how the market and public opinion affect research, this book considers both the risks and the benefits of combining genetic and reproductive technologies.Concluding with a cautionary call for increased regulation, Reprogenetics introduces fact, history, and reason into a public discussion of complex and vexing issues.

Reprogramming Microbial Metabolic Pathways

by Peter Quinn Jian Chen Xiaoyuan Wang

Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production.

Reprogramming the Brain: A Guide to the Future of the Brain and Neuromodulation by a Patient and his Doctor

by Alfonso Fasano Benjamin Stecher

In June 2021, Doctor and Patient decided that time had come to surgically implant two six-inch-long metal alloy spikes all the way through Ben’s brain. It was felt that the medications Ben was taking to control his Parkinson’s disease had become unmanageable. Back then, Ben was taking about 20 different pills a day. Each pill, if it absorbed properly, would activate the dopamine pathways in his brain and induce uncontrollable writhing movements that would last for about an hour. He would then get about 20 minutes where he’d feel somewhat normal before the slowness and tremor kicked in again. So, he’d take another pill and the cycle would repeat.After months of adjusting his medication and finding just the right settings on his deep brain stimulator, it was decided, for the first time ever in a clinical trial in North America, to flip on the adaptive settings.This is the story of how that decision was made and what happened next.

Reptile Medicine and Surgery in Clinical Practice

by Robert Johnson Bob Doneley Deborah Monks Brendan Carmel

A concise and practical quick reference guide to treating reptiles in first opinion veterinary practice Reptile Medicine and Surgery in Clinical Practice is the ideal guide for the busy veterinarian treating reptile cases. Designed as a quick reference guide, but with comprehensive coverage of all the topics needed for first opinion practice, the book presents the principles of reptile medicine and surgery. Richly illustrated chapters cover anatomy, physiology, behaviour, husbandry, reproduction, common diseases and disorders, and much more. Application in a clinical setting is emphasized throughout, including guidance on the physical examination, diagnostic testing and imaging, treatment options, and anaesthetic and surgical techniques. Practical quick-reference guide—ideal for the busy, first-opinion veterinary practitioner Richly illustrated in full colour throughout Edited by a team of highly experienced exotic animal veterinarians Useful reference for those studying for postgraduate certificates in exotic animal medicine With contributions from experts around the globe, Reptile Medicine and Surgery in Clinical Practice is a valuable reference offering a balanced international view of herpetological medicine.

Reptiles and Amphibians: Self-Assessment Color Review, Second Edition (Veterinary Self-Assessment Color Review Series)

by Fredric L. Frye

Much has happened in the 19 years since the publication of the first edition of Reptiles and Amphibians: Self-Assessment Color Review. Many more scientists and clinicians have taken an interest in reptiles and amphibians, novel radiographic techniques have been developed, and veterinary surgeons have devised operative solutions to numerous serious

Reputation and Power

by Daniel Carpenter

The U.S. Food and Drug Administration is the most powerful regulatory agency in the world. How did the FDA become so influential? And how exactly does it wield its extraordinary power? Reputation and Power traces the history of FDA regulation of pharmaceuticals, revealing how the agency's organizational reputation has been the primary source of its power, yet also one of its ultimate constraints. Daniel Carpenter describes how the FDA cultivated a reputation for competence and vigilance throughout the last century, and how this organizational image has enabled the agency to regulate an industry as powerful as American pharmaceuticals while resisting efforts to curb its own authority. Carpenter explains how the FDA's reputation and power have played out among committees in Congress, and with drug companies, advocacy groups, the media, research hospitals and universities, and governments in Europe and India. He shows how FDA regulatory power has influenced the way that business, medicine, and science are conducted in the United States and worldwide. Along the way, Carpenter offers new insights into the therapeutic revolution of the 1940s and 1950s; the 1980s AIDS crisis; the advent of oral contraceptives and cancer chemotherapy; the rise of antiregulatory conservatism; and the FDA's waning influence in drug regulation today. Reputation and Power demonstrates how reputation shapes the power and behavior of government agencies, and sheds new light on how that power is used and contested.Some images inside the book are unavailable due to digital copyright restrictions.

Requiem for the Bone Man: A Novel

by R. A. Comunale

Requiem for the Bone Man is a moving, compelling first novel, told with the assurance and skill of a born storyteller. It is also a meditation on the art of healing, as seen in the adventures of its unforgettable central character, Dr. Robert Galen. From his youth as a street-smart son of immigrants to his career as a gifted physician, Galen is tough-minded yet compassionate. Above all, he is deeply human, willing to risk the pain of loss and failure that inevitably comes to those with an unshakeable commitment to a vocation and to friends and loved ones.

Requirements Engineering for Digital Health

by Samuel A. Fricker Christoph Thümmler Anastasius Gavras

Healthcare and well-being have captured the attention of established software companies, start-ups, and investors. Software is starting to play a central role for addressing the problems of the aging society and the escalating cost of healthcare services. Enablers of such digital health are a growing number of sensors for sensing the human body and communication infrastructure for remote meetings, data sharing, and messaging. The challenge that lies in front of us is how to effectively make use of these capabilities, for example to empower patients and to free the scarce resources of medical personnel. Requirements engineering is the process by which the capabilities of a software product are aligned with stakeholder needs and a shared understanding between the stakeholders and development team established. This book provides guide for what to look for and do when inquiring and specifying software that targets healthcare and well-being, helping readers avoid the pitfalls of the highly regulated and sensible healthcare domain are and how they can be overcome. This book brings together the knowledge of 22 researchers, engineers, lawyers, and CEOs that have experience in the development of digital health solutions. It represents a unique line-up of best practices and recommendations of how to engineer requirements for digital health. In particular the book presents: · The area of digital health, e-health, and m-health · Best practice for requirements engineering based on evidence from a large number of projects · Practical step-by-step guidelines, examples, and lessons-learned for working with laws, regulations, ethical issues, interoperability, user experience, security, and privacy · How to put these many concerns together for engineering the requirements of a digital health solution and for scaling a digital health product For anybody who intends to develop software for digital health, this book is an introduction and reference with a wealth of actionable insights. For students interested in understanding how to apply software to healthcare, the text introduces key topics and guides further studies with references to important literature.

Rescue

by Anita Shreve

Is love always worth saving - no matter what the cost?The car crash should have killed her. But rookie paramedic Peter Webster takes the emergency call, and helps the young woman, Sheila Arsenault, to survive. After the accident, she haunts his thoughts, despite his misgivings about getting involved with a patient. Soon he is embroiled in an intense love affair and in Sheila's troubled life. Eighteen years later, Sheila is long gone and Peter is raising their daughter, Rowan, alone. But Rowan is veering dangerously off course and for the first time in their quiet life together Peter fears for her future. He seeks out the only person who may be able to help Rowan, although Sheila's return is sure to unleash all the questions Peter has been carefully keeping at bay: Why would a mother leave her family? How did the marriage of two people in love unravel?

Rescue Team (Grace Medical #2)

by Candace Calvert

"Calvert is an ER nurse who brings the reader not only a great romantic story, but a glimpse into the chaos of an urban medical clinic."--ROMANTIC TIMES Tired of running from her past, nurse Kate Callison intends to become Austin Grace Hospital's permanent ER director and make Texas her home. Despite staff friction, she's moving ahead. Then unthinkable tragedy wraps the ER in crime tape, brings swarms of media, legal chaos... and a search-and-rescue hero who seems determined to meddle in her life. For Wes Tanner, nothing beats finding someone who's lost; he's known that helpless terror firsthand. That's why he's committed to extending a lifeline of hope to others as a rescue volunteer. He's ready for anything--except Austin Grace's prickly and dismissive ER director. As Kate and Wes discover more about each other, new respect becomes something deeper. Kate wonders if her heart might finally have found a home. But when a startling missing person's case unearths secrets and opens old wounds, she fears that all they've found will just as quickly be lost. CANDACE CALVERT is a former ER nurse and author of the Mercy Hospital and Grace Medical series. Her medical dramas offer readers a chance to "scrub in" on the exciting world of emergency medicine, wife, mother, and very proud grandmother, Candace makes her home in northern California. Please visit her website at www.candacecalvert.com.

Rescued by Dr. Rafe (Stranded in His Arms #1)

by Annie Claydon

Her unexpected rescuer When newly qualified paramedic Mimi Sawyer is separated from her colleague in a flash flood, the last person she wants to come to her rescue is Dr. Rafe Chapman-the man who broke her heart when he walked out five years ago... Talking about his feelings has never been easy for Rafe. But their forced reunion means confronting the truth of the past. It's suddenly clear that Mimi has always been the one for him, yet to win her back he'll need to convince Mimi that he's the one for her!

Rescued by Her Mr. Right: Healed By Her Army Doc (bondi Bay Heroes) / Rescued By Her Mr Right (bondi Bay Heroes) (Bondi Bay Heroes #4)

by Alison Roberts

Dancing in the best man’s arms……is her biggest risk of all!In this Bondi Bay Heroes story, injured nurse Harriet Collins agrees to let hunky paramedic Jack Evans get her fighting fit and back on the Specialist Disaster Response team. After all, it’s purely platonic, right? Plus she’s already nursing a broken heart. But when she’s the bridesmaid and Jack’s the best man at their teammates’ wedding, Harriet wonders if it could be more…

Rescued by Her Rival (Harlequin Lp Medical Ser. #Vol. 1031)

by Amalie Berlin

From fighting fires…To fighting attraction!Firefighter medic Lauren Autry was devastated when she lost out on her dream job as a smoke jumper to golden boy Beck Ellison. Two years later she’s trying again and surprised to see her nemesis with the rookies on probation. Beck is more brooding than ever, but still as maddeningly handsome. A wildfire forces them to work together, but it’s the flaming attraction raging between them that Lauren is desperately trying to put out…“The healing powers of love are working overtime! Excellent characters and attention grabbing … highly recommend!”— Goodreads on Healed Under the Mistletoe“This was such an emotionally-charged story, which I loved from start to finish…a wonderfully-crafted tale…”— Harlequin Junkie on Back in Dr. Xenakis’ Arms

Rescued by Mr. Wrong

by Cynthia Thomason

Life is meant to be lived Surprising her family for Christmas seems like a good idea...until Carrie Foster loses control of her car in a freak blizzard. Now she's stuck in the middle of nowhere with a fractured leg, the unplanned-for guest of the man who saved her life. Keegan Breen lives in a secluded cabin on his family's neglected campgrounds, which nature-lover Carrie sees as a potential paradise. The haunted war correspondent is a world away from the boy he was once. But together, can they prove the cynics wrong and show that opposites can not only attract, but be soul mates?

Rescued by the Dreamy Doc

by Amy Andrews

Nurse Callie Duncan tells herself she's finally put the pieces of her life back together. Then drop-dead-gorgeous world-renowned psychologist Sebastian Walker arrives at her hospital. . . . Seb recognizes the pain behind Callie's beautiful face and fiery temperament and decides they might be just what each other needs for a very welcome distraction!Nights spent in the roguish Seb's strong arms jump-start Callie's badly broken heart. And now the fiercely independent Callie must let this dreamiest of doctors deliver a real fairy-tale ending.

Rescued by the Single Dad Doc: Rescued By The Single Dad Doc / The Midwife's Secret Child (the Midwives Of Lighthouse Bay) (Mills And Boon Medical Ser.)

by Marion Lennox

“So you’re rescuing me? Like you’ve rescued three kids and a dog already?”Life has taught Dr. Rachel Tilding the hard way that she can’t afford to let her guard down—ever! Except her new boss, Dr. Tom Lavery, hasn’t read the memo. He’s known for sheltering all manner of waifs and strays, and Rachel feels uncomfortably like Tom’s latest project! She should be pushing back, but somehow Tom and his boys are starting to heal her wounded heart…“What an entertaining, fast-paced, emotionally-charged read Ms. Lennox has delivered in this book…. The way this story started had me hooked immediately….”—Harlequin Junkie on The Baby They Longed For“…the chemistry between this couple was strong and present from the moment they come face-to-face, as these two still have pretty intense feelings for each other; the romance was heart-warming….”—Harlequin Junkie on Finding His Wife, Finding a Son

Rescued by the Single Dad: Rescued By The Single Dad / The Doctor's Marriage For A Month (Mills And Boon Medical Ser.)

by Emily Forbes

Falling in love…With her rescuer!When paramedic Patrick Reeves discovers Dr. Charli Lawson trapped after a landslide, he holds her hand until she’s freed. They will never forget the connection of that night, but Patrick is a single dad with a broken heart, and Charli has already lost everything! She tries to stay away but he slips past her defenses. Could her courageous but scarred rescuer—and his adorable three-year-old—help heal Charli’s lonely heart?“This is the best book I’ve read by Ms. Forbes so far and I was hooked right from the beginning….”— Harlequin Junkie on Reunited with Her Brooding Surgeon“…it was riveting and tugged at my heartstrings due to the emotional back story of the heroine and all this couple go through on their journey to happy ever after.”— Harlequin Junkie on One Night That Changed Her Life

Rescuing Dr. Ryan

by Caroline Anderson

The injured hero!Will Ryan is supposed to be training Lucie Compton as a family doctor, yet here he is with two injured arms, relying on her for every undignified little thing! It’s more than his pride can take.She disrupts his peace, his life, his dignity—and she’s beautiful! She’s loud, willful and the dog prefers her to him. She’s kind, thoughtful…and he’s dreaming about her! Not that he’d ever tell her.Lucie decides to save this grumpy but gorgeous soul from himself—and get him to pursue his real desires! In fact, she makes rescuingDr. Ryan her very next challenge….

Rescuing the Paramedic's Heart: Falling Again For The Animal Whisperer / Rescuing The Paramedic's Heart (bondi Beach Medics) (Bondi Beach Medics #1)

by Emily Forbes

You can’t heal a heart……by keeping your distanceParamedic Poppy is back in Sydney. Her first stop? Bondi Beach’s surf and sand! There’s just the small matter of bumping into the bay’s newest elite lifeguard—Ryder Evans, her first love, who was forced to move away…taking a piece of Poppy’s heart with him. If she wants him back, she must be bold enough to let gorgeous Ryder show her what she’s been missing.From Harlequin Medical: Life and love in the world of modern medicine.Bondi Beach MedicsBook 1: Rescuing the Paramedic’s Heart

Research Coproduction in Healthcare

by Ian D. Graham Jo Rycroft-Malone Anita Kothari Chris McCutcheon

A ground-breaking and rigorous presentation of coproduction in research In Research Coproduction in Healthcare, a team of experienced applied health researchers and decision makers deliver a robust exploration of collaborative ways on how to plan and conduct healthcare research. The book explores relational skills that are essential to achieving successful coproduction, including trust through humility, ongoing communication, emotional intelligence, and the structures and processes required to work with a range of knowledge users. It also sets out the fundamentals of research coproduction and its transformative potential for more effective and efficient health systems and improved health outcomes. Readers will also find: A thorough introduction to the planning, implementation and evaluation of research coproduction, including how to write a successful research coproduction proposal Comprehensive explorations of capacity-building and infrastructure requirements Practical discussions of the theory of coproduction, including treatments of power and tokenism In-depth reflections on the essential building blocks of research coproduction Perfect for researchers, knowledge users, funders, trainees and organizations, Research Coproduction in Healthcare will also earn a place in the libraries of coproduction teams, policymakers, clinicians, and health system managers.

Research Degrees for Health Professionals

by Richard Hays Lesley Hallam

Interested in undertaking research training? More health professionals are considering enrolling in a postgraduate degree that includes research training, and many are choosing to do this part-time within already busy personal and professional lives. Many are also choosing to conduct research in areas that involve more than one traditional discipline or are closely linked to their professional practice. The challenges they will face are quite different to those of typical full-time students moving on from a first degree. This practical book guides health professionals, and the academic faculty who supervise them, through developing research ideas based on professional practice to successful completion and graduation with either masters or doctoral level degrees. Research training can be a complex process. It is daunting trying to juggle a personal and professional life, and help and advice on this is otherwise hard to find. This book is ideal for healthcare professionals undertaking, or considering undertaking part-time research training. It is also invaluable for full-time research students, and will be a great source of information for academic supervisors and course organisers. 'This book is written for all those poor souls who feel an inclination to undertake further education in a way that answers questions relevant to their work. Research training does not need to be seen as daunting. There is a wide range of research training available, from lower level coursework modules through to higher level, research project-based programmes, many of them designed for full-time study. Few practicing health professionals have the time or the inclination to suspend professional work and study full-time, and so embark on complex pathways that combine research and professional practice. The choice of pathways is potentially confusing and there are numerous challenges to reaching a satisfactory outcome and maintaining sanity. With careful planning, prediction of potential pressure points, and early detection of challenges and intervention, research training even amidst complex lives, can be very rewarding and even life-changing.' - Richard Hays, in the Preface.

Research Design in Chinese Medicine: Linking Social and Health Sciences

by Dongcheng Li

Research Design in Chinese Medicine: Linking Social and Health Sciences is an innovative and comprehensive guide that bridges the ancient wisdom of Traditional Chinese Medicine (TCM) with modern research methods in social and health sciences. Authored by an expert with a background in Chinese medicine and a doctorate in education from Johns Hopkins University, this book is set to revolutionize the way TCM is studied and practiced in the contemporary world.Designed for a diverse readership, from TCM students and practitioners to those in social sciences and holistic medicine, the book provides a unique integration of traditional techniques and modern research approaches. It offers invaluable resources for Doctor of Acupuncture and Herbal Medicine (DAHM) students, helping them deepen and refine their research skills. Additionally, it serves as an essential academic tool for educators in TCM and related fields, perfectly suited for course adoption in over 50 accredited acupuncture schools within the U.S. and extending its reach globally.Research Design in Chinese Medicine: Linking Social and Health Sciences offers a balanced emphasis on both qualitative and quantitative research approaches. This holistic methodology ensures that readers gain a full spectrum of knowledge, from formulating research questions to conducting ethical studies. The step-by-step guide provided in the book is supplemented with a wealth of resources, including a dedicated website, downloadable templates, and case studies, making it not just a book but a complete learning experience.The book is positioned to be a key resource in the field of TCM research. Its interdisciplinary approach and practical guidance make it invaluable to anyone looking to conduct meaningful research in TCM. The combination of the author's expertise and the practical tools offered makes this book a must-have for students, practitioners, and researchers in the field.

Research Design: Quantitative, Qualitative, Mixed Methods, Arts-Based, and Community-Based Participatory Research Approaches

by Patricia Leavy

This user-friendly book provides a step-by-step guide to using the five major approaches to research design: quantitative, qualitative, mixed methods, arts-based, and community-based participatory research. Chapters on each approach follow a unique format--they present a template for a research proposal and explain in detail how to conceptualize and fill in every section. Terminology commonly used within each approach is identified, and key moments of ethical decision making are flagged. Interdisciplinary research examples draw on current events and social justice topics. Unique coverage includes hot topics: replication studies and data sharing, tailoring proposals to different audiences, and more. The book also includes a general introduction to social research; an in-depth, practical discussion of ethics; and a chapter on how to begin a research study, from planning a topic to developing a research question via a literature review. Pedagogical Features *Multiple "Review Stops" in each chapter--quick quizzes with answer keys. *End-of-chapter writing exercises, research activities, and suggested resources. *Bold-face key terms and an end-of-book glossary. *Boxed tips from experts in the respective approaches. *Supplemental PowerPoint slides for instructors using the book in a class.

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