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Rechtmäßigkeit ärztlicher Maßnahmen an transidenten und intersexuellen Minderjährigen (MedR Schriftenreihe Medizinrecht)
by Philine DiesselhorstDieses Buch untersucht die rechtlichen Fragen, die sich im Rahmen der ärztlichen Behandlung transidenter und intersexueller Minderjähriger stellen. Im ersten Teil des Werkes werden die medizinisch-biologischen Grundlagen von Transidentität und Intersexualität sowie der medizinische und gesellschaftliche Umgang mit beiden Phänomenen dargestellt. Anschließend folgt eine Auseinandersetzung mit der Bedeutung des Geschlechts im Recht und der personenstandrechtlichen Behandlung transidenter und intersexueller Personen. Im darauffolgenden Hauptteil des Werkes werden zunächst die allgemeinen Voraussetzungen rechtmäßigen ärztlichen Handelns analysiert und sodann auf die speziellen Fallgruppen der Transidentität und Intersexualität angewendet, wobei ein besonderes Augenmerk auf die Indikationsstellung und die Einwilligung durch einen Minderjährigen selbst beziehungsweise durch die sorgeberechtigten Eltern gelegt wird. Zudem erfolgt eine vertiefte Analyse des § 1631e BGB. Schließlich wird die rechtliche Behandlung beider Fallgruppen unter Berücksichtigung der bestehenden tatsächlichen Unterschiede in einen Vergleich gesetzt und die Frage erörtert, ob die aktuelle Rechtslage den jeweiligen spezifischen Anliegen beider Fallgruppen gerecht wird.
Rechtsfragen der Fernbehandlung (MedR Schriftenreihe Medizinrecht)
by Jonas SiglmüllerDieses Buch analysiert und bewertet die Rechtslage zur Durchführung medizinischer Behandlungen bei örtlichem und/oder zeitlichem Versatz auf dem Gebiet des Standesrechts, des Haftungsrechts, des Werberechts, des Rechts der medizinischen Verordnungen, des SGB V-Leistungsrechts, des Medizinprodukterechts und des Datenschutzrechts.
Rechtsfragen der Obduktion und postmortalen Gewebespende
by Albrecht Wienke Kathrin Janke Markus A. RothschildBei über 95 % aller Verstorbenen in Deutschland bestehen nach wie vor keine autoptisch gesicherten Erkenntnisse über die eigentliche Todesursache und etwaige Begleiterkrankungen. Die auf einer solchen unsicheren Datenlage beruhenden gesundheitspolitischen Entscheidungen zu Disease-Management-Programmen, zu Prävention und strukturellen Maßnahmen der Krankenversorgung entsprechen damit nicht der erforderlichen Evidenz. Dies hat zugleich negative Auswirkungen auf die Qualität ärztlicher Diagnostik und Therapie und somit auf die Patientensicherheit. Zudem machen es die sehr unterschiedlichen Rechtsgrundlagen in den Landesgesetzen über das Leichen-, Bestattungs- und Friedhofswesen den betroffenen Angehörigen und den Mediziner in der praktischen Umsetzung der oft widerstreitenden Interessen nicht leicht. Die klinische und anatomische Sektion ist nach derzeit allgemeiner Meinung auch im wissenschaftlichen Interesse oder zu Ausbildungszwecken ohne Zustimmung des Verstorbenen oder seiner Angehörigen unzulässig. Die medizinische Forschungs- und Ausbildungssituation wird durch diese Zustimmungslösung nachhaltig beeinträchtigt; eine erweiterte Widerspruchslösung könnte hierbei viele Hindernisse in der praktischen Handhabung beseitigen. Die DGMR hat sich in ihren aktuellen Empfehlungen daher für eine gesetzliche Abkopplung der postmortalen Gewebespende von der Organtransplantation im Transplantationsgesetz ausgesprochen, um die seit Jahren niedrige Obduktionsquote in Deutschland nachhaltig zu verbessern. Der vorliegende Tagungsband gibt die Referate und die Empfehlungen der DGMR zur Obduktion und postmortalen Gewebespende wieder.
Rechtsfragen der Personalisierten Medizin
by Albrecht Wienke Christian Dierks Kathrin JankeDie Personalisierte Medizin (auch Individualisierte Medizin) eröffnet neue Perspektiven für Prädiktion, Diagnostik, Therapie und Medikamentenentwicklung. Die Auswahl von Medikation und Dosierung in Abhängigkeit individueller Besonderheiten durch den Nachweis von Biomarkern und die Abstimmung der pharmakotherapeutischen Optionen auf die molekularen Besonderheiten eines Tumors in der Onkologie sind Beispiele dieses medizinischen Konzepts. Die damit einhergehenden Rechtsfragen berühren das Arztrecht, das Arzneimittelrecht, das Recht der Krankenversicherungen und das Datenschutzrecht. Die DGMR hat in ihrem Einbecker Workshop im Frühjahr 2013 mit Experten der Medizin und der Rechtswissenschaften die Rechtsfragen der Personalisierten Medizin in einem Workshop erarbeitet und dazu Empfehlungen beschlossen. Damit liegen zusammengefasste Erkenntnisse in diesem noch jungen Bereich vor, die die weiteren Diskussionen bereichern sollen.
Rechtsmedizin (Springer-Lehrbuch)
by Reinhard Dettmeyer Florian Veit Marcel VerhoffWie bestimmt man den Todeszeitpunkt? Wie werden die verschiedenen Gewalteinwirkungen diagnostiziert? Wie lässt sich ermitteln, welche Rolle Alkohol bei der Todesursache spielt? Und wie sehen die Rechtsbeziehungen zwischen Arzt und Patient aus?Über die Arbeit des Rechtsmediziners bestehen sehr unterschiedliche Vorstellungen. Mit dem Lehrbuch Rechtsmedizin werden diese Vorstellungen konkret. Kompakt und sehr praxisnah werden alle Themen der Rechtsmedizin behandelt. Und das ganz übersichtlich:Zahlreiche Fallbeispiele geben einen Einblick in die PraxisDefinitionen machen sofort klar, worum es gehtMehr als 100 Tabellen bringen die Fakten auf den Punkt und helfen beim schnellen LernenMehr als 220 Abbildungen machen die Rechtsmedizin anschaulichMerksätze für das Wichtigste in einem SatzHier finden Sie alles Notwendige für die Prüfung: die ärztliche Leichenschau, eine ausführliche Forensik, das Medizinrecht und vieles mehr. Durch die praxisnahe Darstellung ist das Buch sowohl für Studierende als auch für Ärzte und Mitarbeiter von Polizei- und Justizbehörden hervorragend geeignet.
Rechtsmedizin
by Reinhard Dettmeyer Florian Veit Marcel VerhoffWie bestimmt man den Todeszeitpunkt? Wie werden die verschiedenen Gewalteinwirkungen diagnostiziert? Wie lässt sich ermitteln, welche Rolle Alkohol bei der Todesursache spielt? Und wie sehen die Rechtsbeziehungen zwischen Arzt und Patient aus?Über die Arbeit des Rechtsmediziners bestehen sehr unterschiedliche Vorstellungen. Mit dem Lehrbuch Rechtsmedizin werden diese Vorstellungen konkret. Kompakt und sehr praxisnah werden alle Themen der Rechtsmedizin behandelt. Und das ganz übersichtlich:Zahlreiche Fallbeispiele geben einen Einblick in die PraxisDefinitionen machen sofort klar, worum es gehtMehr als 100 Tabellen bringen die Fakten auf den Punkt und helfen beim schnellen LernenMehr als 220 Abbildungen machen die Rechtsmedizin anschaulichMerksätze für das Wichtigste in einem SatzHier finden Sie alles Notwendige für die Prüfung: die ärztliche Leichenschau, eine ausführliche Forensik, das Medizinrecht und vieles mehr. Durch die praxisnahe Darstellung ist das Buch sowohl für Studierende als auch für Ärzte und Mitarbeiter von Polizei- und Justizbehörden hervorragend geeignet. Die vierte Auflage wurde sorgfältig aktualisiert und erweitert.
Rechtsmedizin: Befunderhebung, Rekonstruktion, Begutachtung
by Burkhard MadeaDIE Rechtsmedizin - einzigartig im deutschsprachigen Raum Umfassend Alle aktuellen Erkenntnisse und Standards der RechtsmedizinFundort für spezielle DetailfragenGültig im gesamten deutschsprachigen Raum (Deutschland, Österreich, Schweiz)Die Basis für jedes GutachtenSicherheit für die Facharztprüfung Rechtsmedizin Praxisrelevant Leitlinienbasierte praktische Anleitungen zu Vorgehensweisen und Methoden für die tägliche ArbeitFundierte Übersichten und ChecklistenKommentierte Gesetzestexte und FalldarstellungenKooperation und Schnittstellenmanagement zwischen Sachverständigen, Behörden und Institutionen NEU u.a. Neueste molekularbiologische Analytik, z. B. prädiktive Phänotypisierung und molekulare AltersschätzungNeueste toxikologische Analytik, z. B. neue psychoaktive SubstanzenInfektionsdiagnostikCOVID-19 assoziierte TodesfälleKlinische Rechtsmedizin und forensische SexualmedizinAlkoholismusmarkerNeueste gesetzliche Regelung, z. B. § 81e StPO, neue Psychoaktive-Stoffe-GesetzAktuelle Entwicklungen zur Akkreditierung und Qualitätssicherung Nach den Leitlinien und Vorgaben DGRM Deutsche Gesellschaft für RechtsmedizinGTFCh Gesellschaft für Toxikologische und Forensische ChemieEU RecommendationIALM International Academy of Legal MedicineISFG International Society for Forensic Genetics „Rechtsmedizin“ bietet für jede Fragestellung der Rechtsmedizin eine Antwort – als verlässliche Informationsquelle und Nachschlagewerk. Für Rechtsmediziner, Pathologen, Toxikologen, Biologen, Kriminologen, Kriminalisten und Juristen in Klinik, Labor, Sektionssaal und Gericht.
Rechtsmedizin für Dummies (Für Dummies)
by Frank RamsthalerWir alle kennen die Forensik aus verschiedenen Filmen und Serien. Doch jetzt besuchen Sie einen Kurs in Rechtsmedizin an der Universität? Mit diesem Buch decken Sie Mythen der Filme und Serien auf und entdecken die reale Welt der Rechtsmedizin. Dieses Buch bietet die ideale Basis und erklärt verständlich die Grundlagen. Von Pathologie und Physiologie des Todes, über die Identifizierung eines unbekannten Toten bis zu modernen forensischen Techniken und vieles mehr finden Sie in diesem Buch.
Rechtsmedizinische Aspekte in der Notfallmedizin: Für den Rettungsdienst- und Notarzteinsatz
by Sieglinde Ahne Thomas Ahne Michael BohnertDieses Taschenbuch liefert Mitarbeitern im Rettungsdienst und Notärzten anhand von zahlreichen Fallbeispielen rechtsmedizinisches Praxiswissen für die Erstversorgung von Notfallpatienten. Themen sind u.a. Leichenschau, Verhalten am Tatort, stumpfe und scharfe Gewalt, Strangulation, Schussverletzungen, Tötungsdelikte und Suizid. Auch Besonderheiten bei plötzlichem Kindstod, Kindesmisshandlung und Sexualdelikten werden berücksichtigt. Die 2. Auflage erscheint komplett überarbeitet, aktualisiert und um das Thema Kinderschutz erweitert.
The Recipient: A Pyschological Medical Thriller
by Dean MayesHer heart is dying.Casey Schillinge is a vivacious young woman on the verge of making her mark on the world. While backpacking, she is struck down by a tropical disease and suffers cardiac failure. But at the eleventh hour, Casey receives a life-saving heart transplant and a rare second chance to begin again.Her new heart is changing her.Three years later, Casey has become a withdrawn shell of her former self: she is estranged from her loved ones, afraid of open spaces and rides the line between legitimate and criminal work. The worst of her troubles come in the form of violent night terrors; so frightening that she resorts to extreme measures to keep herself from sleeping.What is her heart revealing?When she can take no more, she embarks on a desperate search for the source of her dreams. In so doing, she makes a shocking discovery surrounding the tragic fate of the donor whose heart now beats inside her chest. As she delves deeper into the mystery of her donor, she realizes her dreams are not a figment of her imagination, but a real-life nightmare.Will her heart end up killing her after all?"As Dean takes you on an adrenaline-fuelled ride that twists to a kicker of a climax, ultimately uncovering a tale of human horror that is all too real, he will keep you guessing throughout as you try and figure out just who the good guys and the bad guys are. A word of warning – trust no-one as you race towards the very satisfying conclusion of this gripping psychological thriller!" - Marcia B, Book Muster Down Under"Entwining very real social issues with fast-paced adventure and fascinating dream sequences, Mayes has created a story that successfully combines suspense, dark humor, cultural references, action and outright horror, an intense examination of what motivates the terrible crimes perpetrated in the novel. Be prepared for a wild ride!" - Abbie Williams, author of The Shore Leave Cafe series"Overall, a great read that was fascinating medically and had great character development." - Christina Boswell, Manhattan Book ReviewBe sure to also read Dean Mayes' other novels:The Hambledown DreamGifts of the PeramangkThe Artisan Heart
Recipient States in Global Health Politics
by Ricardo PereiraEven if constrained in their international choices, recipient countries of global health programmes hold the capacity to autonomously define and pursue their own strategies, policies, and ultimately attain political goals. This is comparatively demonstrated through the analysis of PEPFAR's implementation in Botswana, Ethiopia and South Africa.
Recipient Vessels in Reconstructive Microsurgery: Anatomy and Technical Considerations
by Raffi Gurunian Risal DjohanThis book offers a comprehensive review of reconstructive microsurgery with an emphasis on the recipient vasculature. Chapters describe the anatomy, exposure, and technical considerations of recipient vessels in reconstructive microsurgery. The book strives to fill that void of literature covering recipient vessels and their surgical exposure for microvascular anastomosis. Alongside nuanced description for each particular body structure, the chapters will provide illustrations and short video clips on how to prepare these essential vessels. The book is the accumulation of the editors’ many years of experience in Asia, Europe, and the United States and also features contributions from world experts. Recipient Vessels in Reconstructive Microsurgery -- Anatomy and Technical Considerations is a must-have resource for trainees and residents as well as surgeons working in plastic surgery and microsurgery.
Reciprocity and Dependency in Old Age
by Sue ThompsonThis book highlights (1) the significance of reciprocity for the maintenance of self-esteem in old age and (2) the negative implications for the well-being of dependent older people when that significance goes unrecognized and, as a consequence, opportunities to give back to society, as well as take from it, are not facilitated by those in a position to do so. The discussion draws on research undertaken in the UK and Southern India into the extent to which having the self-perception of being valued in the world is important to older people in receipt of care support and whether, in their experience, this is recognized by others. The author presents an analysis of theoretical insights from leading thinkers across a broad range of literature and from several disciplines, including social theory, social work, philosophy, and gerontology. The author also gives voice to the perspectives of those dependent older people not often heard because of marginalizing and disempowering processes that contribute to their having little opportunity to be heard in the first place. The emphasis of this book is on aspiration to a meaningful life and continuing personal growth as offering a challenge to dominant discourses the equate old age with decline.
Reclaim Your Life from IBS: A Scientifically Proven CBT Plan for Relief Without Restrictive Diets
by Melissa G. HuntReclaim Your Life from IBS teaches a number of skills that can directly reduce the impact of gastrointestinal symptoms in a person’s life. The book explores the differential diagnosis of irritable bowel syndrome (IBS) and the current scientific models of what causes IBS. It teaches the reader the cognitive model of stress management using cognitive-behavioral therapy and helps readers learn to identify their negative beliefs and reframe them more accurately. It also guides readers to reduce avoidance and helps them understand how to use dietary modifications and medications wisely, rather than reactively. In this second edition, numerous case examples throughout illustrate the application of these core CBT skills to IBS-related thoughts and experiences, and new material is included on exercise, diet, and medications. This book is a proven self-help book for people with IBS, as well as being useful as a treatment manual for clinicians who work with patients with IBS.
Reclaiming the Self in Psychiatry: Centering Personal Narratives for a Humanist Science
by Şerife TekinReclaiming the Self in Psychiatry: Centering Personal Narratives for Humanist Science diagnoses the fundamental problem in contemporary scientific psychiatry to be a lack of a sophisticated and nuanced engagement with the self and proposes a solution—the Multitudinous Self Model (MuSe).MuSe fulfils psychiatry’s twin commitments to patients’ flourishing and scientific objectivity. Marshalling the conceptual and empirical resources from testimonies from individuals diagnosed with mental disorders, substantive research in cognitive science, and empirically informed philosophy, MuSe provides clinicians, scientists, and patients pathways to respond to mental distresses and disorders. This framework boosts psychiatry’s relationship to science by facilitating expansive notions of expertise and objectivity in which some patients are recognized as “experience-based experts” whose contributions to psychiatric knowledge are indispensable. Şerife Tekin draws the contours of a future for psychiatry that is grounded in philosophy, medical humanities, and social sciences as much as physiology and neuroscience.This book is an ideal read for professional psychiatrists and philosophers of psychiatry who are interested in the philosophy of mental health.
Recoding: Expansion of Decoding Rules Enriches Gene Expression
by Raymond F. Gesteland John F. AtkinsThe genetic code is dynamic - it, or its readout, can be specifically changed by mRNA signals that modify the behavior of on-board ribosomes. Many viruses use recoding to maximize utilization of information in small genomes, and probably all organisms use recoding in at least some genes for expanding the regulatory repertoire. The volume will detail specific recoding examples to understand the mechanisms and the mRNA signals. It will continue to detail the biochemical and genetic approaches to identify and study the cellular factors involved in recoding. The signals in mRNA that dictate recoding often include complex folded structures of the RNA, which we are studying by a combination of microbiology, genetics, biochemical and NMR approaches.
Recognising Autism and Asperger’s Syndrome: A Practical Guide to Adult Diagnosis and Beyond
by Trevor PowellRecognising Autism and Asperger’s Syndrome is an accessible guide, offering information and guidance, self-help and coping strategies and illustrated throughout with personal quotes, vignettes and anecdotes from clients with autism with whom the author has worked clinically. The book captures the individual stories, quotations and experiences, observed in adult autism diagnostic services, woven in with contemporary research, theory and clinical insights. It outlines the history of the condition and the present criteria for obtaining a diagnosis. With exercises, tips, questionnaires, psycho-educational work and advice sheets, this new edition also elucidates the female presentation of autism that has attained significance in the recent times. The book is deliberately aimed at a broad audience of people: those who have just received a diagnosis and want to know more, those who are considering seeking a diagnosis, family members, relatives, friends and clinicians, including mental health workers, psychologists, support workers and all those who work with autistic people.
Recognition and Alleviation of Pain in Laboratory Animals
by National Research Council of the National AcademiesThe use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare.
Recognizing and Correcting Developing Malocclusions
by Eustáquio A. Araújo Peter H. BuschangRecognizing and Correcting Developing Malocclusions: A Problem-Oriented Approach to Orthodontics provides an evidence-based approach to early treatment, an often-controversial topic. Based on decades of experience in clinical practice and education, Drs. Araújo and Buschang clearly present treatment protocols for mixed-dentition patients with various malocclusions and other orthodontic problems. Class I, Class II, and Class III malocclusions are covered extensively, along with eruptive deviations and open-bite malocclusions. The literature is comprehensively reviewed to ensure that the reader thoroughly understands the development, phenotypic characteristics and etiology of each type of malocclusion. Taking a problem-oriented approach, the authors provide detailed information for each case, develop comprehensive problem lists, and then provide evidence-based treatment solutions. The clinical focus of the text is ideal suited for private-practice clinician, with numerous references and academic underpinnings to ensure its suitability for orthodontic and pediatric dentistry residents. Focuses solely on mixed dentition orthodontic treatments Great variety of case studies--5 to 10 cases per chapter Each case is presented in the format of a problem list and evidence-based solutions More than 300 clinical photographs and radiographs
Recognizing and Correcting Developing Malocclusions: A Problem-Oriented Approach to Orthodontics
by Eustáquio A. Araújo Peter H. BuschangComprehensive reference providing an evidence-based approach to the early treatment, recognition, and correction of developing malocclusions Recognizing and Correcting Developing Malocclusions, Second Edition provides an evidence-based approach to early treatment of developing malocclusions, presenting treatment protocols for mixed-dentition patients with various malocclusions and other orthodontic problems. Class I, Class II, and Class III malocclusions are covered extensively, along with eruptive deviations and different malocclusions. The literature is comprehensively reviewed to ensure that the reader thoroughly understands the development, phenotypic characteristics, and etiology of each type of malocclusion. Taking a problem-oriented approach, the authors provide detailed information for each case, develop comprehensive problem lists, and then present evidence-based treatment solutions. This newly revised and updated Second Edition contains comprehensive updates to all chapters and sections, including dental trauma and its consequences and sleep apnea in children. Containing figures, tables, patient pictures, and 3D rendered illustrations throughout to elucidate key concepts, Recognizing and Correcting Developing Malocclusions, Second Edition explores topics including: Assessing the degree of severity of a developing malocclusion and recognizing and correcting intra-arch deviationsGenetics of dental occlusions and malocclusions and mixed dentition orthodontic mechanicsStrategies for managing missing second premolar teeth in young patients and principles and techniques of premolar autotransplantationAbnormal eruption, function, and aesthetics, congenitally missing teeth, autotransplantation, and habitsConstruction of a diagnosis, treatment plan, and estimation of prognosis based on available diagnostic records produced by both old and new technologies Practical in approach but grounded in the literature, Recognizing and Correcting Developing Malocclusions, Second Edition is equally useful as a patient-side guide for clinicians and as a detailed reference for orthodontic and pediatric specialists and residents.
Recognizing Child Abuse in Radiology
by Alan E. Oestreich Marguerite M. CaréThis book is both a personal review of experience in the diagnosis of child abuse and its differential diagnosis, intended to instruct beginners, and a reliable source of information for the more experienced health care provider. Emphasis is placed on normal findings that simulate abuse, true and false diagnoses of metabolic bone disease as the cause of fractures, abusive head trauma, and the problem of zealous abuse-denying "experts. " Plain radiography is emphasized, with appropriate mention of, ultrasound, CT, MRI, - in detecting childhood abuse is clearly explained, and individual chapters focus on neuroradiological evaluation and the radiological assessment of abdominal, thoracic, and subcutaneous abnormalities. Guidance is provided on how to exclude a range of alternative diagnoses, on the documentation of concerns over potential abuse, and on the needs of the clinician in relation to the radiologist. Recognizing Child Abuse in Radiology will be of value for radiologists in training and practice, for health care workers, and for other interested professionals.
Recognizing the Past in the Present: New Studies on Medicine before, during, and after the Holocaust
by Sabine Hildebrandt, Miriam Offer Michael A. GrodinFollowing decades of silence about the involvement of doctors, medical researchers and other health professionals in the Holocaust and other National Socialist (Nazi) crimes, scholars in recent years have produced a growing body of research that reveals the pervasive extent of that complicity. This interdisciplinary collection of studies presents documentation of the critical role medicine played in realizing the policies of Hitler’s regime. It traces the history of Nazi medicine from its roots in the racial theories of the 1920s, through its manifestations during the Nazi period, on to legacies and continuities from the postwar years to the present.
Recognizing the Past in the Present: New Studies on Medicine before, during, and after the Holocaust
by Sabine Hildebrandt, Miriam Offer Michael A. GrodinFollowing decades of silence about the involvement of doctors, medical researchers and other health professionals in the Holocaust and other National Socialist (Nazi) crimes, scholars in recent years have produced a growing body of research that reveals the pervasive extent of that complicity. This interdisciplinary collection of studies presents documentation of the critical role medicine played in realizing the policies of Hitler’s regime. It traces the history of Nazi medicine from its roots in the racial theories of the 1920s, through its manifestations during the Nazi period, on to legacies and continuities from the postwar years to the present.
Recombinant and In Vitro RNA Synthesis
by Graeme L. ConnThe discovery of catalytic RNAs in the mid-1980s marked the beginning of a new era in RNA biology and an ever increasing appreciation of the diverse and critical roles played by this fascinating molecule. In Recombinant and In Vitro RNA Synthesis: Methods and Protocols, expert researchers in the field detail approaches from the inception of a new RNA project to the final sample ready for analysis. These experimental protocols combine established work-horse approaches with some of the latest innovative methods for RNA synthesis and purification. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Recombinant and In Vitro RNA Synthesis: Methods and Protocols aids scientists in continuing to study the fascinating world of RNA.
Recombinant Antibodies for Cancer Therapy
by Martin Welschof Jürgen KraussIn Recombinant Antibodies for Cancer Therapy: Methods and Protocols, Martin Welschoff and Jürgen Krauss present a collection of carefully selected protocols for the design, construction, and characterization of novel anticancer therapeutics based on recombinant antibody technology. These readily reproducible methods include coverage of hybridoma-derived recombinant antibodies, recombinant antibody fragments from phagemid-displayed antibody repertoires, antibody fragments with additional properties, and large-scale production of recombinant antibodies for clinical applications. Concise review articles also survey the current status of recombinant antibodies in cancer therapy, as well as the generation of antibody molecules through antibody engineering.