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The Chemistry of Mycotoxins
by Stefan Bräse Anna M. Linsenmeier Stephanie Lindner Bettina M. Ruff Sabilla Zhong Franziska Gläser Carsten Kramer Anne C. Meister Kye-Simeon MastersThe biological activity of mycotoxins ranges from weak and/or sometimes positive effects, such as antibacterial activity (see penicillin derivatives derived from Penicillium strains) to strong mutagenic (e. g. aflatoxins, patulin), carcinogenic (e. g. aflatoxins), teratogenic, neurotoxic (e. g. ochratoxins), nephrotoxic (e. g. fumonisins, citrinin), hepatotoxic, and immunotoxic (e. g. ochratoxins, diketopiperazines) activity. Nowadays, many laboratories around the world are specialized in the detection of mycotoxins in food products and contaminated material found in housing. In this volume, a focus on the most important classes of mycotoxins is provided and their chemistry of the last ten years is discussed. In each Section, the individual biological impact is outlined. Sections are arranged according to mycotoxin classes (e. g. aflatoxins) and/or structural classes (e. g. resorcinyl lactones, diketopiperazines). The biology of mycotoxins is also described.
The Chemistry of PCB'S
by Otto HutzingerThe literature on chlorinated biphenyl is growing rapidly. Review articles on PCB's cited in this book usually contained a section on the toxicity of PCB. The structure and nomenclature are detailed. The chapters and topics included are (1) commercial PCB preparations: properties and compositions, (2) synthesis of chlorobiphenyls, (3) chemical reactions of chlorobiphenyls, (4) photodegradation of chlorobiphenyls, (5) metabolism of chlorobiphenyls, (5) mass spectroscopy of chlorobiphenyls, (6) nuclear magnetic resonance of chlorobiphenyls, (7) ultraviolet spectroscopy of chlorobiphenyls, (8) infrared spectrometry of chlorobiphenyls, (9) determination of chlorobiphenyls, and (10) recent developments.
The Chemokine System in Experimental and Clinical Hematology
by Oystein BruserudThe aim of the issue is to describe and explain the importance of the chemokine system in hematology. The chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.
The Chiari Malformations
by R. Shane Tubbs Mehmet Turgut W. Jerry OakesThis unique, contemporary book is the successor edition of a ground-breaking, authoritative title devoted to the pathology and treatment of chiari malformations. Since an abundance of research and development has occurred after the publication of the Chiari Malformations this updated title meets the market need for a reference that reflects such advances in the field. Chiari Malformations, 2nd Edition is divided into nine sections. Opening sections feature chapters on general aspects, diagnostic features and clinical presentation. These are followed by sections on differential diagnosis, treatment and prognosis. Finally, the book closes with an extensive discussion on research, related pathologies and patient resources. Expertly written chapters are supplemented with numerous high-quality illustrations and images to aid in visual learning.An impressive, nuanced successor, Chiari Malformations, 2nd Edition, is an invaluable resource for neuroscientists and clinicians at all levels, as well as graduate students to specific research scientists studying this region.
The Chiari Malformations
by R. Shane Tubbs W. Jerry OakesOnce an uncommon clinical finding, the Chiari malformations are now frequently seen with the advent of more sophisticated imaging modalities. With more than one hundred years of experience with these entities, medicine currently has a much better understanding of the embryology and pathophysiology of the disorder. Long-term outcome studies are becoming more prevalent and patients are commonly operated on with generally favorable results. Comprehensive in design, the The Chiari Malformations focuses on the two most common forms of hindbrain herniation, the Chiari I and II malformations. Since the original description and classification of hindbrain hernias more than one hundred and twenty years ago, the Chiari malformations have revealed much of their pathophysiology and have become easily diagnosed radiologically. Indeed with the availability of MRI, more and more patients are being labeled with the diagnosis but without symptoms or appropriate symptoms. Timely and an invaluable addition to the literature, The Chiari Malformations thoroughly details the progress that has been made with our understanding of these conditions, their radiologic definition, details of operative intervention and prediction of outcome.
The Chicago Review Press NCLEX-RN Practice Test and Review (NCLEX Practice Test and Review series)
by Linda Waide Berta RolandFully revised to conform to the 2004 NCLEX Test Plan, this study guide and test includes "hot spot," fill-in-the-blank, and select-all-that-apply questions to reflect the new test format. Ten written practice tests cover all the body systems and two additional practice tests cover mental health and miscellaneous topics. Each practice test includes a system overview and complete explanations for both correct and incorrect answers. In addition to the written tests, a 100-item interactive software CD in the NCLEX format is included to allow students to become comfortable with the on-screen exam.
The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
by Domenico RibattiThe chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane which serves as a gas exchange surface and its function is supported by a dense capillary network. Because of its extensive vascularization and easy accessibility, the CAM has been broadly used to study the morpho-functional aspects of the angiogenesis process in vivo and to investigate the efficacy and mechanisms of action of pro-angiogenic and anti-angiogenic natural and synthetic molecules. The CAM is a suitable site for transplanting tissues, which can survive and develop in the CAM by peripheral anastomoses between graft and original CAM vasculature or by new angiogenic vessels grown from the CAM that invade the graft. While the formation of peripheral anastomoses between host and pre-existing donor vessels is the main, and the most common, mechanism involved in the revascularization of embryonic grafts, the growth of CAM-derived vessels into the graft is only stimulated in tumor grafts. The CAM has long been a favored system for the study of tumor angiogenesis and metastasis, because at this stage the chick immunocompetence system is not fully developed and the conditions for rejection have not been established. Tumors remain avascular for 72 h, after which they are penetrated by new blood vessels and begin a phase of rapid growth. Also, delivery of tumor cells onto the CAM allows the fine study of the effects of tumor derived angiogenic growth factors on blood vessel structure and functionality. The CAM may also used to verify the ability to inhibit the growth of capillaries by implanting tumors onto the CAM and by comparing tumor growth and vascularization with or without the administration of an anti-angiogenic molecule. Other studies using the tumor cells/CAM model have focused on the invasion of the chorionic epithelium and the blood vessels by tumor cells. The cells invade the epithelium and the mesenchymal connective tissue below, where they are found in the form of a dense bed of blood vessels, which is a target for intravasation.
The Chick and the Dead: Life and Death Behind Mortuary Doors
by Carla ValentineA mortician explains the autopsy process—and what it can teach us about the living—with “a morbidly galloping parade of every possible kind of dead body” (New York Times).Carla Valentine works with the dead. After studying forensics, she assisted pathologists with post-mortems for years before becoming the curator of the world’s most famous pathology museum. When it comes to death, she truly is an expert, and in this book she shares that expertise.Using the most common post-mortem process as the backbone of the narrative, she takes us through the process of an autopsy while also describing the history and changing cultures of our relationship with the dead. The book is full of vivid insight into what happens to our bodies in the end. Each chapter considers an aspect of an autopsy alongside an aspect of Carla’s own life and work, and touches on some of the more controversial aspects of our feelings about death, including the relationship between sex and death and our attitudes toward human tissue collection.Starting with the first cut, we move from external examination into the body itself, discovering more about the heart, stomach, and brain, and into dismembered and reconstructed bodies, at each stage taking a colorful detour into the question of what these things can teach us about the living. Join Carla on the journey from microscope-requesting nine-year-old to pathology educator and death engager at a Victorian museum (a journey made via around 5,000 autopsies) as she tells the story of exactly what it’s like to live a life immersed in death.Praise for Carla Valentine’s The Science of Murder“A breezy and accessible look at the history of forensic science.” —Publishers Weekly“Utterly superb.” —Deanna Raybourn, New York Times–bestselling author of the Veronica Speedwell Mysteries
The Chicken Health Handbook, 2nd Edition: A Complete Guide to Maximizing Flock Health and Dealing with Disease
by Gail DamerowHealthy chickens are happy chickens. This one-of-a-kind reference book covers the health problems that plague chickens of all breeds and ages. Practical charts identify common symptoms and causes of infection, while an alphabetic listing of diseases provides advice on treatment. You’ll find helpful descriptions of troublesome ailments of all types, from poor egg production to crooked toe syndrome. Practical remedies and gentle preventative care measures will help your beloved flock stay happy, healthy, and safe.
The Chief Concern of Medicine: The Integration of the Medical Humanities and Narrative Knowledge into Medical Practices
by Ronald Schleifer Vannatta Jerry B.Unlike any existing studies of the medical humanities, The Chief Concern of Medicine brings to the examination of medical practices a thorough---and clearly articulated---exposition of the nature of narrative. The book builds on the work of linguistics, semiotics, narratology, and discourse theory and examines numerous literary works and narrative "vignettes" of medical problems, situations, and encounters. Throughout, the book presents usable expositions of the ways storytelling organizes itself to allow physicians and other healthcare workers (and even patients themselves) to be more attentive to and self-conscious about the information---the "narrative knowledge"---of the patient's story.
The Child Surveillance Handbook
by David Hall Jonathan Williams David EllimanPrevious editions of "The Child Surveillance Handbook" have built its reputation as the essential reference guide for GPs, health visitors and other members of the healthcare team in primary care. Now thoroughly revised and updated, this new edition remains the authoritative guide to child surveillance - promoting the health, welfare and life chances of children.
The Child Who Never Grew: A Memoir
by Pearl S. BuckA &“groundbreaking&” memoir about raising a special-needs daughter in an era of misinformation and prejudice—a classic that helped transform our perceptions (Publishers Weekly). It was my child who taught me to understand so clearly that all people are equal in their humanity and that all have the same human rights. Pearl S. Buck is known today for earning a Nobel Prize in Literature and for such New York Times–bestselling novels as The Good Earth. What many do not know is that she wrote that great work of art with the motivation of paying for a special school for her oldest daughter, Carol, who had a rare developmental disorder. What was called &“mental retardation&” at the time—though some used crueler terms—was a disability that could cause great suffering and break a parent&’s heart. There was little awareness of how to deal with such children, and as a result some were simply hidden away, considered a source of shame and stigma, while others were taken advantage of because of their innocence. In this remarkable account, which helped bring the issue to light, Pearl S. Buck candidly discusses her own experience as a mother, from her struggle to accept Carol&’s diagnosis to her determination to give her child as full and happy a life as possible, including a top-quality education designed around her needs and abilities. Both heartrending and inspiring, The Child Who Never Grew provides perspective on just how much progress has been made in recent decades, while also offering common sense and timeless wisdom for the challenges still faced by those who love and care for someone with special needs. It is a clear-eyed and compelling read by a woman renowned for both her literary talent and her humanitarian spirit. This ebook features an illustrated biography of Pearl S. Buck including rare images from the author&’s estate.
The Child Who Rescued Christmas
by Jessica MatthewsFor nurse Sara Wittman, life with husband Cole is perfect...until they discover having a much-wanted baby just isn't happening. When Cole learns of a two-year-old son he never knew existed, they face a crash course in parenting! It could be the happiest Christmas ever, once they realize that little Brody's unexpected arrival is the answer to their dreams....
The Child and His Family
by Buhler, CharlotteFirst published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.
The Child in Mind: A Child Protection Handbook
by Judy Barker Deborah HodesFirst published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.
The Child in You: The Breakthrough Method for Bringing Out Your Authentic Self
by Stefanie StahlThe breakthrough million-copy international bestseller about how to befriend your inner child to find happiness"Compassionate, clear-eyed, and insightful . . . The Child in You is like your own personal therapist that you can carry around with you." --Lori Gottlieb, New York Times bestselling author of Maybe You Should Talk to SomeoneWe all want to be loved and to feel safe to express who we really are. But over time we grow estranged from what brings us our purest happiness--because everyday traumas, unyielding societal expectations, and the judgment of our parents and peers submerge our true self beneath layers of behaviors rooted in fear and shame and mistrust. In The Child in You, psychologist Stefanie Stahl guides you, step-by-step, through her therapeutic method that has helped millions to peel away these layers and reconnect with their inner child--both the shadow child, representing our deepest insecurities and the part of our self-esteem that is injured and unstable, and the sun child, representing our greatest joys and the part of our self-esteem that remains positive and intact.The many examples and exercises in this book will help you discover your shadow child and sun child, identify which of the shadow child's dozen self-protection strategies are at work in you, and put into practice the array of proven self-reflection strategies to overcome negative influences and beliefs. Because it's never too late to have a happy childhood, or to bring your authentic self out from the shadows so you can embody your radiant individuality.A PENGUIN LIFE TITLE
The Child's Discovery of Death: A study in child psychology (International Library Of Psychology Ser.)
by Anthony, SylviaRoutledge is now re-issuing this prestigious series of 204 volumes originally published between 1910 and 1965. The titles include works by key figures such asC.G. Jung, Sigmund Freud, Jean Piaget, Otto Rank, James Hillman, Erich Fromm, Karen Horney and Susan Isaacs. Each volume is available on its own, as part of a themed mini-set, or as part of a specially-priced 204-volume set. A brochure listing each title in the "International Library of Psychology" series is available upon request.
The Child's Unconscious Mind: The Relations of Psychoanalysis to Education
by Lay, WilfridFirst published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.
The Childhood Immunization Schedule and Safety
by Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization ScheduleVaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U. S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. "The Childhood Immunization Schedule and Safety" identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.
The Children in Child Health: Negotiating Young Lives and Health in New Zealand (Rutgers Series in Childhood Studies)
by Julie SprayWho are the children in child health policy? How do they live and see the world, and why should we know them? A journey into the lives of children coping in a world compromised by poverty and inequality, The Children in Child Health challenges the invisibility of children’s perspectives in health policy and argues that paying attention to what children do is critical for understanding the practical and policy implications of these experiences. In the unique context of indigenous Māori and migrant Pacific children in postcolonial New Zealand, Julie Spray explores the intertwining issues of epidemic disease, malnutrition, stress, violence, self-harm, and death to address the problem of how scholars and policy-makers alike can recognize and respond to children as social actors in their health. The Children in Child Health innovatively combines perspectives from childhood studies, medical anthropology, and public health and policy together with evocative ethnography to show how a deep understanding of children’s worlds can change our approach to their care.
The Children's Doctor and the Single Mom
by Lilian DarcyThe doctor takes a family! Tammy Prunty is an excellent neonatal-intensive-care nurse--and a single mom of five children! There's simply no time in her life for relationships. Besides, she's sworn off men for good! Her gorgeous colleague, neonatal specialist Laird Burchell, is definitely out of the question. He's a playboy, way out of her league and not the kind of man who'd even think about taking on five kids. But Laird's been bowled over by Tammy's warmth, her sense of humor and her gorgeous red hair. He might be daunted by the prospect of fatherhood, but there's so much about Tammy and her lively young family that makes him think she's a woman worth risking everything for....
The Children's Doctor's Special Proposal (The London Victoria #2)
by Kate HardyNew pediatrician Rhys Morgan was everything the hospital grapevine promised: piercing blue eyes, perfect physique and a mysteriously guarded manner. He was also Katrina's boss, but since a previous relationship with a colleague had seriously damaged her confidence, she thought she was safe from Rhys's charms. That is until she discovered they shared a deep commitment to their little patients--and a heartfelt passion for each other.For Rhys, Katrina was nothing short of a miracle. He had never believed in happy families. Yet Katrina opened his eyes to what love and family really meant, and her courage and vulnerability created a fierce desire within Rhys to protect her. A desire that could make him risk his heart with the most special proposal of all....
The Children's Health Insurance Program: Past and Future
by David G. SmithThe Children's Health Insurance Program was crafted in a period of intense partisan and ideological controversy over health care entitlements to provide -creditable coverage- for American children below 200 percent of the Federal Poverty Level. This objective was widely supported, though achieved only by a compromise between the structural alternatives of a block grant, similar to the Maternal and Child Health Block Grant or an entitlement resembling Medicaid. According to David G. Smith, the CHIP compromise has been a successful experiment that far exceeded expectations, both in identifying and enrolling -targeted low-income children- and in earning political capital. He argues that beyond this core mission, the reauthorization of CHIPRA (Children's Health Insurance Program Reauthorization Act of 2009) invites a larger mission: going beyond enrollment of children to include assuring access, improving quality, and containing costs of health care for them. Extending this thrust, the author notes that CHIP could be used to establish children's health as a niche--much like care for the elderly--within the larger scheme of health care insurance for all. Several areas of successful performance needed for the program to be adjudged a success as well as its limitations are discussed in the book. These areas include initial implementation, enrolling kids, federal-state relations, and the uses and misuses of waivers to modify the program. A description of changes made by the CHIPRA reauthorization and the new Patient Protection Affordable Care Act (PPACA) is also included. This is followed by a consideration of lessons learned from CHIP's evolution and recommendations for future development. In short, this is a valuable and readable account for those interested in the current and future trends of health care for the young.
The Children's Heart Surgeon
by Meredith WebberTop pediatric heart surgeon Alex Attwood gives all his caring to his tiny patients. He's not interested in women…not since the blond stranger he kissed one long-ago night and never found again. So Alex is shocked to meet the new nurse manager of the Children's Cardiac Unit at St. James's Hospital. Annie Talbot has a different name from his mystery woman, and she dyes her hair brown. She also flatly denies ever having met him. But one thing Annie can't hide is her response to his kiss…. Jimmie's Children's Unit…where hearts are mended!
The Children's Hospital
by Chris AdrianA hospital is preserved, afloat, after the Earth is flooded beneath seven miles of water. Inside, assailed by mysterious forces, doctors and patients are left to remember the world they've lost and to imagine one to come. At the center, Jemma Claflin, a medical student, finds herself gifted with strange powers and a frightening destiny.