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The Know-It-Alls: The Rise of Silicon Valley as a Political Powerhouse and Social Wrecking Ball
by Noam CohenThe world&’s tech giants are at the centre of controversies over fake news, free speech and hate speech on platforms where influence is bought and sold. Yet, at the outset, almost everyone thought the internet would be a positive, democratic force, a space where knowledge could be freely shared to enable everyone to make better-informed decisions. How did it all go so wrong? Noam Cohen reports on the tech libertarians of Silicon Valley, from the self-proclaimed geniuses Jeff Bezos, Peter Thiel, Reid Hoffman and Mark Zuckerberg to the early pioneers at Stanford University, who have not only made the internet what it is today but reshaped society in the process. It is the story of how the greed, bias and prejudice of one neighbourhood is fracturing the Western world.
The Knowledge: Your guide to female health – from menstruation to the menopause
by Dr Nighat ArifTHE ESSENTIAL WOMEN'S HEALTH BIBLECelebrated GP Dr Nighat Arif brings women's health to the forefront in this extensive guidebook designed to help everyone better understand each of the three key stages of a woman's life: the puberty years, the fertility years and the peri/menopausal years. Every step of the way, Dr Nighat will help you get to know the female body by explaining what is normal, what to expect, how to care for yourself and when to seek help. This book tackles many important topics: from the help available for people with conditions like endometriosis and polycystic ovary syndrome to the symptoms of heart disease to look out for in women.The Knowledge is for everyone - and this book encompasses all experiences, including the perspectives of women of colour, people of all abilities and cultures, and the transgender community to ensure that all groups affected by female health concerns are a part of vital conversations. This is a life-saving book for all genders, ages and communities. From the young preteen hoping to understand their first period, to the couple experiencing fertility issues, to the single father raising teenage daughters, to the person unknowingly experiencing early signs of gynaecological cancer: this book is an indispensable asset for us all.
The Knowledge: Your guide to female health – from menstruation to the menopause
by Dr Nighat ArifTHE ESSENTIAL WOMEN'S HEALTH BIBLECelebrated GP Dr Nighat Arif brings women's health to the forefront in this extensive guidebook designed to help everyone better understand each of the three key stages of a woman's life: the puberty years, the fertility years and the peri/menopausal years. Every step of the way, Dr Nighat will help you get to know the female body by explaining what is normal, what to expect, how to care for yourself and when to seek help. This book tackles many important topics: from the help available for people with conditions like endometriosis and polycystic ovary syndrome to the symptoms of heart disease to look out for in women.The Knowledge is for everyone - and this book encompasses all experiences, including the perspectives of women of colour, people of all abilities and cultures, and the transgender community to ensure that all groups affected by female health concerns are a part of vital conversations. This is a life-saving book for all genders, ages and communities. From the young preteen hoping to understand their first period, to the couple experiencing fertility issues, to the single father raising teenage daughters, to the person unknowingly experiencing early signs of gynaecological cancer: this book is an indispensable asset for us all.
The Knowledgeable Patient: Communication and Participation in Health (CBS- Cochrane Book Series #2)
by Sophie HillLearn how to place communication and participation at the heart of evidence-based healthcare The Knowledgeable Patient: Communication and Participation in Health sits at the forefront of the challenging, changing 21st century landscape. The 'knowledgeable patient' as an individual can take many forms: patient, family carer, consumer advocate, or member of the public interested in health issues. In each of these roles, knowledgeable patients interact with health professionals by asking questions about the evidence for treatment, seeking support, exchanging views, and contributing experiences and new ideas on how to improve the health system. Drawing from several research paradigms, The Knowledgeable Patient is an essential guide to a new era of complex healthcare. Integrating consumer stories and evidence from systematic reviews, it examines key communication and participation issues in a range of contexts, including: surgery safe medicine use chronic disease self management the complexity of multimorbidity notification of rare disease risk. The Knowledgeable Patient is international in scope with researched examples spanning living in the community, health service treatment, governance, and policy making. It provides health professionals with new ideas, concepts, evidence, and practical tools to understand the central role of communication and participation to a well-functioning health system. It is an ideal reference for undergraduate and postgraduate students studying the health sciences. Watch a video about The Knowledgeable Patient: Communication and Participation in Health from the author, Sophie Hill: bit.ly/xNYCqG
The Kock Pouch
by Pär Myrelid Mattias BlockThis book is about the recently revived technique of Kock pouch in inflammatory bowel disease. It discusses the Kock pouch as an alternative to patients not suitable for a pelvic pouch or where the pelvic pouch has failed. It provides clinicians with all the necessary information on patient guidance and surgical revisions after a long life with a Kock pouch. The reader will learn about the development of the pouch, pre and post-operative strategies, surveillance, complications and the limitations and weaknesses of the method. New pioneering experimental methods used by the authors are also discussed. The use of ileorectal anastomosis and Kock’s continent ileostomy has regained interest as the long term problems of the pelvic pouch have and this book brings the knowledge and valuable experiences of a few experts at international centres to a large audience. This is an indispensable guide for colorectal surgeons, gastroenterologists and stoma therapists involved in the care of patients with inflammatory bowel disease where colectomy is still needed, either in an emergency setting or due to dysplasia or cancer.
The LDN Book, Volume Two: The Latest Research on How Low Dose Naltrexone Could Revolutionize Treatment for PTSD, Pain, IBD, Lyme Disease, Dermatologic Conditions, and More
by Linda ElsegoodA comprehensive examination of Low Dose Naltrexone—a little-known drug with big potential&“[LDN] raises hopes of reversing memory loss in old age.&”—the GuardianA drug that is simultaneously affordable, devoid of severe side effects, and applicable to a wide range of diseases is not often found in the modern pharmaceutical landscape. But as medical professionals and researchers alike continue to discover, Low Dose Naltrexone (LDN) boasts this remarkable combination.LDN, originally prescribed in higher doses as a treatment for opioid addiction, works by blocking opioid receptors, thereby stimulating the production of endorphins, mitigating the inflammatory process, and stabilizing the immune response. Prescribed off-label and administered in small daily doses, this generic drug has proven useful in treating many different ailments.Expanding on the information presented in The LDN Book, Volume 1, which showcased LDN&’s efficacy in treating conditions such as lupus, thyroiditis, autism spectrum disorder, and chronic fatigue, Volume 2 highlights the latest clinical trials, case studies, and research with explanations from a dozen medical professionals on how they are using LDN to help patients suffering from:Chronic painParkinson&’s diseaseDermatologic conditionsTraumatic brain injuryLyme disease and moreThe LDN Book, Volume 2 is both a resource for practitioners, pharmacists, and patients, and a renewed call for further research on the healing potential of this generic drug.
The Labor Progress Handbook
by Penny Simkin Ruth AnchetaThe third edition of The Labor Progress Handbook builds on the success of first two editions and remains an unparalleled resource on simple, non-invasive interventions to prevent or treat difficult labor. Features new to this edition include two new chapters on third and fourth stage labor management and low-technology interventions, a complete analysis of directed versus spontaneous pushing, and additional information on massage techniques.
The Labor Progress Handbook: Early Interventions to Prevent and Treat Dystocia
by Penny Simkin Lisa Hanson Ruth AnchetaPraise for the previous edition: "This…edition is timely, useful, well organized, and should be in the bags of all doulas, nurses, midwives, physicians, and students involved in childbirth."–Journal of Midwifery and Women's Health The Labor Progress Handbook: Early Interventions to Prevent and Treat Dystocia is an unparalleled resource on simple, non-invasive interventions to prevent or treat difficult or prolonged labor. Thoroughly updated and highly illustrated, the book shows how to tailor one’s care to the suspected etiology of the problem, using the least complex interventions first, followed by more complex interventions if necessary. This new edition now includes a new chapter on reducing dystocia in labors with epidurals, new material on the microbiome, as well as information on new counselling approaches specially designed for midwives to assist those who have had traumatic childbirths. Fully referenced and full of practical instructions throughout, The Labor Progress Handbook continues to be an indispensable guide for novices and experts alike who will benefit from its concise and accessible content.
The Laboratory Bird (Laboratory Animal Pocket Reference)
by Douglas K Taylor Vanessa K Lee Karen R StraitLaboratory animals, including birds, play an important role in biomedical research. The humane care and management of these animals is an ongoing concern. A new addition to the acclaimed Laboratory Animal Pocket Reference series, The Laboratory Bird is the first publication dedicated to the care and use of avian species in the research setting.Cove
The Laboratory Canine (Laboratory Animal Pocket Reference)
by Garrett Field Todd A. JacksonLaboratory animals, including dogs, play an important role in biomedical research and medical advances. Dogs have a long history of use in research and have contributed enormously to the health and welfare of both humans and animals. The humane care and management of these animals is a fundamental component of their use in medical research.T
The Laboratory Cat (Laboratory Animal Pocket Reference)
by Brent J. MartinThis guide was created especially for individuals performing research with cats whose duties include animal facility management, animal husbandry, regulatory compliance, and technical procedures involved with their research. Basic information and common procedures are presented in detail.
The Laboratory Ferret (Laboratory Animal Pocket Reference)
by C. Andrew Matchett Rena Marr Felipe M. Berard Andrew G. Cawthon Sonya P. SwingLaboratory animals, including ferrets, play an important role in biomedical research and advances. The humane care and management of these animals remains an ongoing concern. Published in color to provide greater clarity to the techniques and concepts discussed, The Laboratory Ferret presents basic information and common procedures in detail to pro
The Laboratory Guinea Pig
by Donna J. Clemons Jennifer L. SeemanLaboratory animals play an important role in biomedical research and advances. Expanded, updated, and now published in full color to provide greater clarity to the techniques and concepts discussed, this guide presents basic information and common procedures in detail to provide a quick reference for investigators, technicians, and caretakers in the laboratory setting. It includes additional information on the research uses of the guinea pig along with updated medical care information.
The Laboratory Hamster and Gerbil (Laboratory Animal Pocket Reference)
by Karl J. Field Amber L. SiboldThe Laboratory Hamster and Gerbil details basic information and common procedures for individuals performing research with hamsters and gerbils. It includes duties of animal facility management, animal husbandry, regulatory compliance, and technical procedures and assists in the humane care and use of hamsters and gerbils in the laboratory. It prov
The Laboratory Mouse (Laboratory Animal Pocket Reference)
by Mark A. Suckow Sara Hashway Kathleen R. Pritchett-CorningWith the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to reflect advances since the second edition, The Laboratory Mouse continues to be the most accessible reference on the biology and care of the mouse in research settings. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers on the humane care and use of the mouse. The new edition adds information on novel technologies such as CRISPR-Cas and on housing systems and management practices; it covers new concepts such as pain assessment by facial expression and the importance of nest-building as an assessment tool of well-being. There are now expanded sections on anesthesia and analgesia, and on behavior and enrichment. An ideal quick reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in a research setting, this book will be particularly valuable to those new to working with mice who need to start research programs using these animals.
The Laboratory Mouse: A Guide to the Location and Orientation of Tissues for Optimal Histological Evaluation
by Susan Ryan Jennifer Johnson Brian DelGiudice Dinesh Bangari Eleanor Peterson Gregory Ulinski Beth ThurbergKey features: High quality full color photographs and descriptive texts on the location and removal of the organs from the mouse Instructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysis Full color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achieved All in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader ‘from the mouse to the microscope’, it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.
The Laboratory Nonhuman Primate (Laboratory Animal Pocket Reference)
by Jeffrey D. Fortman Terry A. Hewett Lisa C. HallidayKey features Contains 28 updated tables designed as quick, easy-to-use references for New and Old World species Provides over 100 photographs and illustrations, most now in color, depicting aspects of nonhuman primate biology, behavior, management practices, diseases, and technical procedures Gives a concise overview of regulatory considerations for the use of nonhuman primates in biomedical research Expands the Veterinary Care chapter to include new sections on nutritional support, behavioral conditions, dental care, and updated information on anesthetic and analgesic drugs Presents step-by-step descriptions of common and advanced sampling techniques Includes extensive resource lists for vendors of animals, feed, sanitation supplies, caging, anesthetic equipment, and veterinary and research supplies Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic husbandry and covers biologic characteristics, regulatory compliance, common diseases, and anesthetic management.The text gives easy-to-follow descriptions of basic technical procedures including restraint, intubation, tuberculin skin testing, and collection of blood and urine samples. It also reviews advanced sampling procedures including collection of bone marrow, cerebrospinal fluid, bronchoalveolar lavage fluid, and rectal mucosal biopsy. The Laboratory Nonhuman Primate presents information in a clear, concise format to allow readers to incorporate concepts and techniques into the standard operating procedures of a facility.
The Laboratory Pig (Laboratory Animal Pocket Reference)
by Kirsten Rosenmay Jacobsen Aage K Olsen Alstrup Axel K. Hansen Peter BollenSince the popular second edition of The Laboratory Swine was published more than a decade ago, the number of pigs used in toxicity studies has increased as an alternative to commonly used non-rodent species, while, at the same time, large developments have been made in welfare concepts of laboratory animals. Pigs have gained prominence in both basic and applied research, leading to a significant increase in publication activity.This third edition summarizes these new insights, raising the bar for humane care and use of pigs, from agricultural sources to genetically and microbiological defined minipigs. Aimed at animal caretakers, technicians, laboratory animal veterinarians, and investigators planning and performing studies on pigs, it provides an overview with extensive references for further study. The book has been updated with a special focus on refined methods for housing and handling pigs, including an updated description of commonly performed experimental and surgical procedures.Continuing its legacy as the premier reference on the care and use of pigs in the laboratory, the small, practical, and accessible format makes this an easy "go-to" book, with easy-to-find information and high-quality color images. The third edition aims to contribute to humane use and care for laboratory pigs in all aspects of housing, husbandry, veterinary care, and experimental techniques.
The Laboratory Rabbit (Laboratory Animal Pocket Reference)
by Mark A. Suckow Valerie Schroeder Fred A. DouglasWith laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting
The Laboratory Rat (Laboratory Animal Pocket Reference)
by Patrick Sharp Jason S. VillanoRats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal h
The Laboratory Small Ruminant (Laboratory Animal Pocket Reference)
by Matthew J. Allen Gary L. BorkowskiThe Laboratory Small Ruminant details basic information and common procedures for individuals performing research with small ruminants. Details include duties of animal husbandry, regulatory compliance, and technical procedures. It is designed to assist in the humane care and use of small ruminants in the laboratory and to provide immediate informa
The Laboratory Swine (Laboratory Animal Pocket Reference)
by Peter J. Bollen Axel K. Hansen Aage K Olsen AlstrupAddressing the biology, husbandry, management, veterinary care and research applications of both large and miniature swine, this color resource is renowned as the laboratory reference on swine. It is thoroughly updated and includes a major revision to the anesthetics section. It also places a heightened focus on animal welfare and addresses important considerations related to genetically modified swine. The Laboratory Swine, Second Edition is ideal for animal caretakers, technicians, investigators, and laboratory animal veterinarians as a single-source reference that contributes to the humane care and use of swine in research.
The Laboratory Xenopus sp. (Laboratory Animal Pocket Reference)
by Sherril L. GreenXenopus have gained increasing popularity as a laboratory animal and continue to serve as an important part of biomedical research. This book offers a practical reference to the care and maintenance of captive clawed frogs. With full-color illustrations of management practices and technical procedures, the text explores the wide range of responsibilities facing individuals who work with this species, from husbandry, compliance, and veterinary care to housing and water quality management. Numerous figures and tables enhance understanding of concepts. An experienced researcher at a top tier institution, the author provides an invaluable guide for facility technicians and animal caretakers.
The Laboratory Zebrafish (Laboratory Animal Pocket Reference)
by Carole Wilson David ChuThis guide covers all aspects pertaining to the use of zebrafish including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. The zebrafish is now a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management. The new edition includes more figures, tables and bullet points, a wealth of new full-color images, major updates on health and welfare (including colony health surveillance and viruses), and a complete overhaul of the compliance section to address more international concerns.
The Laboratory Zebrafish (Laboratory Animal Pocket Reference)
by Claudia Harper Christian LawrenceLike other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief span