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Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity
by Katharina Spanel-BorowskiIn the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.
Atlas of the Neonatal Rat Brain
by Renuka Ramachandra Thyagarajan SubramanianAtlas of the Neonatal Rat Brain provides photographic, histological illustrations of the anatomical features of the neonatal rat brain at postnatal (P) days P-1, P-7, and P-14. The sections are Nissl stained with Cresyl violet, creating photomicrographs with high resolution and clarity. The structures are directly labeled on the images, making it e
Atlas of the Patellofemoral Joint
by Vicente Sanchis-AlfonsoA picture is worth a thousand words, and the goal of this atlas is to better understand patellofemoral conditions through pictures. Hence the reason we have decided to publish this book, which is a collection of the finest images of patellofemoral joint surgery, supplied by world renowned specialists in Knee surgery. All the images, footnotes and summaries are compiled in order to convey a simple understanding of this complex problem. This is a very practical book, aimed at the general orthopedic surgeon and also those that specialize in surgery of the knee. The book is divided into four sections, the first section focuses on the etiopathogenic bases, the second section focuses on emerging technologies, the third section includes difficult clinical cases studied, and the fourth section provides a description of the most important surgical techniques for the knee extensor mechanism.
Atlas of the Supraaortic Craniocervical Arterial Variations: MR and CT Angiography
by Akira UchinoThis book presents numerous figures of various variations of the supraaortic arteries detected by MR and CT angiography. Improved both MR and CT angiographic image quality permits incidental detection of even small anomalous arterial branches. Although the cerebral arterial variations may have limited clinical significance, their correct diagnosis during MR and CT angiographic image interpretation is important to interventional neuroradiologists as well as both neurosurgeons and otorhinolaryngologists, who must be familiar with arterial variations to prevent complications during surgery. Readers can easily identify arterial variations and make correct diagnosis during image interpretation using this textbook.
Atlas on Narrow Band Imaging in Upper Aerodigestive Tract Lesions
by Rakesh SrivastavaThis book covers all aspects of narrow band imaging (NBI), including research, general principles and diagnostic features in various ENT pathologies. In addition to highlighting the advantages of NBI over white light endoscopy for the detection of early cancers and lesions that are less than 1 cm in diameter, the book offers a step-by-step approach to help readers easily grasp various pathologies of the upper aerodigestive tract. It discusses both malignant and non-malignant aspects of NBI and provides extensive information on inflammatory lesions of the upper aerodigestive tract, including various clinical features of laryngopharyngeal reflux. Subsequent chapters cover the most difficult aspects of NBI in treated mucosa (post-chemo radiated), in which the potential recurrence of disease is a key question. It also addresses the limitations of NBI, including false positive and false negative cases.Given its scope, the book will benefit otolaryngologists, oncosurgeons, radiation oncologists and oral medicine practitioners, as well as graduate students of ENT, radiotherapy, oral medicine and oncosurgery.
Atlas on the Human Testis: Normal Morphology and Pathology
by Davor JežekAtlas on the Human Testis: Normal Morphology and Pathology presents histological illustrative material from paraffin and semi-thin sections of the human testis which are routinely used in the assessment of testicular morphology, allowing an early detection of carcinoma in situ and more advanced pathological changes of the testicular parenchyma. The early detection of cancer in situ is based on the careful morphological investigation of the biopsy and immunohistochemistry (IHC). Therefore, this atlas contains detailed descriptions of IHC methods as well as modern molecular biological methods such as DNA microarrays and proteomics and advanced microscopy techniques related to the testicular biopsy. Adequate evaluation of the testicular biopsy leads to high cure rates of testicular neoplasms which can be used as a basis to successfully treat infertility in men. Atlas on the Human Testis: Normal Morphology and Pathology is a valuable reference tool which will appeal to andrologists, urologists, pathologists, clinical embryologists, as well as reproductive biology scientists.
Atlas sportorthopädisch-sporttraumatologische Operationen
by Andreas B. Imhoff Matthias FeuchtAkute Verletzungen, Verletzungsfolgen von Fehlbelastungen und Überlastungsschäden sind typische Krankheitsbilder in der Sportmedizin. Bei der Behandlung der meist jüngeren Patienten stellt sich für Operateure die Frage nach dem wirkungsvollsten Eingriff. Ein Expertenteam der Technischen Universität München, Abteilung für Sportmedizin, stellt in dem Operationsatlas die 75 am häufigsten durchgeführten Operationsverfahren vor. Alle Operationen sind detailliert beschrieben und mit 300 brillanten Operationszeichnungen versehen.
Atlas sportorthopädisch-sporttraumatologische Operationen (2 Auflage)
by Andreas B. Imhoff Matthias J. FeuchtDargestellt sind 87 sportorthopädisch-sporttraumatologische Operationsverfahren.<P><P> Jede Operation wird step-by-step beschrieben und ist mit zahlreichen brillanten Zeichnungen und Fotos visualisiert.<P> In der 2. Auflage: Alle Inhalte sind aktualisiert und zusätzliche Operationsverfahren erweitern das Spektrum.<P>In diesem Buch sind die 87 am häufigsten durchgeführten Operationsverfahren in der Sportmedizin dargestellt, zumeist arthroskopische Verfahren. Akute Verletzungen, Folgen von Fehlbelastungen und Überlastungsschäden sind die typischen Krankheitsbilder. Betroffen sind oft jüngere Patienten, die nach der Behandlung ihre Sportart wieder aktiv praktizieren möchten. Der Operateur steht nun vor der Frage nach dem schonendsten und wirkungsvollsten Eingriff und dem „How to do“. Das Expertenteam der Technischen Universität München, mit Herrn Prof. Dr. med. Imhoff an der Spitze, gibt mit seinem Operationsatlas Antworten auf diese Fragen. Mit Step-by-Step-Beschreibungen und –Visualisierungen aller Operationen können die Darstellungen als Operationsanleitungen dienen.<P> Für die 2. Auflage wurde das Buch aktualisiert und um zahlreiche zusätzliche Krankheitsbilder und deren operative Behandlung erweitert. Es ist ideal für die Vorbereitung auf die praktische Durchführung von Operationen in der Sportmedizin geeignet.<P> Erweiterungen in der 2. Auflage:<P> · Arthroskopische Methoden der AC-Gelenkstabilisierung.<P> · Minimalinvasive arthroskopische Rotatorenmanschettennaht-Rekonstruktionstechniken.<P> · Radiusköpfchenprothesenimplantation.<P> · Endoskopische Bizepssehnenrekonstruktion.<P> · Mediale und laterale Bandrekonstruktionen bei Epikondylopathie.<P> · Vordere Kreuzbandersatzbandplastiken: bei Partialrupturen, isoliertem Kreuzbandbündelersatz mit arthroskopischen Refixationstechniken und der extraartikulären Stabilisierung.<P> · Posterolaterale Bandrekonstruktion am Kniegelenk.<P> · Ligament bracing bei Multiligamentverletzungen auf der medialen und lateralen Seite des Kniegelenks.<P>
Atlas van de parodontale diagnostiek
by Johan Dijk Fred Spijkervet Jan TrompAtlas parodontale diagnostiek is een onmisbaar hulpmiddel bij het stellen van een diagnose. De eerste uitgave van dit boek verscheen tien jaar geleden. Sindsdien hebben veel ontwikkelingen plaatsgevonden. Vandaar dat het tijd werd voor deze tweede uitgave, waarin diverse hoofdstukken zijn gewijzigd en aangevuld. Net als in de eerste uitgave krijgen, naast diagnostiek, de anatomie en pathologie een belangrijke plaats in dit boek. In de hoofdstukken 'Pathologie' en 'Mucogingivale aandoening' is veel nieuwe kennis opgenomen. Het hoofdstuk 'Effecten van parodontitis op het lichaam', waarin wordt uitgelegd hoe parodontitis en systeemaandoeningen elkaar kunnen beïnvloeden, is volledig herzien. De implantologie heeft in de afgelopen jaren een belangrijke plaats binnen de tandheelkundige zorg ingenomen. Daarom is er een geheel nieuw hoofdstuk opgenomen: 'Diagnostiek van de parodontale weefsels rond het implantaat'. Atlas parodontale diagnostiek is rijk geïllustreerd met klinische en röntgendiagnostische foto's, die een goed beeld van het vakgebied geven. Daarnaast bieden de tabellen en grafieken veel belangrijke informatie. De foto's, tabellen en grafieken worden bondig toegelicht. De tien hoofdstukken in dit boek geven een compleet beeld van de diagnostiek in de parodontologie.
Atmospheric Reactive Nitrogen in China: Emission, Deposition and Environmental Impacts
by Xuejun Liu Enzai DuAtmospheric reactive nitrogen (N) emissions, as an important component of global N cycle, have been significantly altered by anthropogenic activities, and consequently have had a global impact on air pollution and ecosystem services. Due to rapid agricultural, industrial, and urban development, China has been experiencing an increase in reactive N emissions and deposition since the late 1970s. Based on a literature review, this book summarizes recent research on: 1) atmospheric reactive N in China from a global perspective (Chapter 1); 2) atmospheric reactive N emissions, deposition and budget in China (Chapters 2-5); 3) the contribution of atmospheric reactive N to air pollution (e.g., haze, surface O3, and acid deposition) (Chapters 6-8); 4) the impacts of N deposition on sensitive ecosystems (e.g., forests, grasslands, deserts and lakes) (Chapters 9-12); and 5) the regulatory strategies for mitigation of atmospheric reactive N pollution from agricultural and non-agricultural sectors in China (Chapters 13-14). As such it offers graduate students, researchers, educators in agricultural, ecological and environmental sciences, and policy makers a glimpse of the environmental issues related to reactive N in China .
Atom-Probe Tomography: The Local Electrode Atom Probe
by Michael K. Miller Richard G. ForbesNanocharacterization by Atom Probe Tomography is a practical guide for researchers interested atomic level characterization of materials with atom probe tomography. Readers will find descriptions of the atom probe instrument and atom probe tomography technique, field ionization, field evaporation and field ion microscopy. The fundamental underlying physics principles are examined, in addition to data reconstruction and visualization, statistical data analysis methods and specimen preparation by electropolishing and FIB-based techniques. A full description of the local electrode atom probe - a new state-of-the-art instrument - is also provided, along with detailed descriptions and limitations of laser pulsing as a method to field evaporate atoms. Valuable coverage of the new ionization theory is also included, which underpins the overall technique.
Atomic Doctors: Conscience And Complicity At The Dawn Of The Nuclear Age
by James L. NolanAn unflinching examination of the moral and professional dilemmas faced by physicians who took part in the Manhattan Project.After his father died, James L. Nolan, Jr., took possession of a box of private family materials. To his surprise, the small secret archive contained a treasure trove of information about his grandfather’s role as a doctor in the Manhattan Project. Dr. Nolan, it turned out, had been a significant figure. A talented ob-gyn radiologist, he cared for the scientists on the project, organized safety and evacuation plans for the Trinity test at Alamogordo, escorted the “Little Boy” bomb from Los Alamos to the Pacific Islands, and was one of the first Americans to enter the irradiated ruins of Hiroshima and Nagasaki.Participation on the project challenged Dr. Nolan’s instincts as a healer. He and his medical colleagues were often conflicted, torn between their duty and desire to win the war and their oaths to protect life. Atomic Doctors follows these physicians as they sought to maximize the health and safety of those exposed to nuclear radiation, all the while serving leaders determined to minimize delays and maintain secrecy. Called upon both to guard against the harmful effects of radiation and to downplay its hazards, doctors struggled with the ethics of ending the deadliest of all wars using the most lethal of all weapons. Their work became a very human drama of ideals, co-optation, and complicity.A vital and vivid account of a largely unknown chapter in atomic history, Atomic Doctors is a profound meditation on the moral dilemmas that ordinary people face in extraordinary times.
Atomic Force Microscopy in Biomedical Research: Methods and Protocols (Methods in Molecular Biology #736)
by Davide Ricci Pier Carlo BragaWith its ability to explore the surface of the sample by means of a local scanning probe and its use of dedicated software allows to be visualize results, atomic force microscopy (AFM) has revolutionized the study of the smallest aspects of life. Atomic Force Microscopy in Biomedical Research: Methods and Protocols proves that this technology is no longer simply just another form of microscopy but has given rise to a completely new way of using microscopy that fulfils the dreams of all microscopists: being able to touch, move, and interact with the sample while it is being examined, thus making it possible to discover not only morphological but also chemical and physical structural information. Covering such topics as molecule imaging, nanoscale surface analysis and cellular imaging, force-spectroscopy, investigating drug action, and AFM as a nanotool, this volume features the most up-to-date techniques currently in use. Written in the Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and expert tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Atomic Force Microscopy in Biomedical Research: Methods and Protocols brings together different types of applications in order to provide examples from diverse fields in the hope of inspiring researchers to apply their ingenuity in their own specialization and add significant originality to their varying studies.
Atomic and Molecular Spectroscopy: Basic Aspects and Practical Applications (Graduate Texts in Physics)
by Sune SvanbergA wide-ranging review of modern spectroscopic techniques such as X-ray, photoelectron, optical and laser spectroscopy, and radiofrequency and microwave techniques. On the fundamental side the book focuses on physical principles and the impact of spectroscopy on our understanding of the building blocks of matter, while in the area of applications particular attention is given to those in chemical analysis, photochemistry, surface characterisation, environmental and medical diagnostics, remote sensing and astrophyscis. The Fourth Edition also provides the reader with an update on laser cooling and trapping, Bose-Einstein condensation, ultra-fast spectroscopy, high-power laser/matter interaction, satellite-based astronomy and spectroscopic aspects of laser medicine.
Atoms of Mind: The "Ghost in the Machine" Materializes
by W. R. KlemmThis book describes the author's view of how the mind "thinks" at various levels of operation. These levels include nonconscious mind (as in spinal/brainstem reflexes and neuroendocrine controls), subconscious mind, and conscious mind. In the attempt to explain conscious mind, there is considerable critique of arguments over whether or not free will is an illusion. Finally, the author summarizes current leading theories for consciousness (Bayesian probability, chaos, and quantum mechanics) and then presents his own theory based on patterns of nerve impulses in circuits that are interlaced coherently into larger networks.
Atoms, Radiation, and Radiation Protection
by James E. Turner Darryl J. Downing James S. Bogard Robert L. Coleman Keith F. EckermanAtoms, Radiation, and Radiation Protection Discover the keys to radiation protection in the fourth edition of this best-selling textbook A variety of atomic and sub-atomic processes, including alpha, beta, and gamma decay or electron ejection from inner atom shells, can produce ionizing radiation. This radiation can in turn produce environmental and biological effects both harmful – including DNA damage and other impacts of so-called ‘radiation sickness’ – and helpful, including radiation treatment for cancerous tumors. Understanding the processes that generate radiation and the steps which can be taken to mitigate or direct its effects is therefore critical in a wide range of industries and medical subfields. For decades, Atoms, Radiation, and Radiation Protection has served as the classic reference work on the subject of ionizing radiation and its safeguards. Beginning with a presentation of fundamental atomic structure and the physical mechanisms which produce radiation, the book also includes thorough discussion of how radiation can be detected and measured, as well as guide-lines for interpreting radiation statistics and detailed analysis of protective measures, both individual and environmental. Now updated by a new generation of leading scholars and researchers, Atoms, Radiation, and Radiation Protection will continue to serve global scientific and industrial research communities. Readers of the fourth edition of Atoms, Radiation, and Radiation Protection will also find: Detailed updates of existing material, including the latest recommendations of the ICRP and NCRP Treatment of current physiokinetic and dosimetric models All statistics now presented in SI units, making the book more globally accessible Atoms, Radiation, and Radiation Protection is a foundational guide for graduate students and researchers in health physics and nuclear physics, as well as related industries.
Atopic Dermatitis - Eczema: Clinics, Pathophysiology and Therapy
by Johannes Ring Kilian EyerichThis entirely revised edition of the successful work presents the state of the art in clinics, research and practical management of atopic dermatitis - eczema. The wide variability in clinical morphology including differences between age groups and ethnicities is illustrated by color pictures including the typical minimal manifestations or “stigmata” suggestive of atopy. The dramatic rise in the prevalence of this disease over the last few decades is reflected by detailed analyses of epidemiological data from all over the world. In-depth descriptions of key pathophysiological mechanisms including epidermal barrier, molecular genetics, itch pathophysiology and modern cellular immunology offer readers a deeper understanding of the complex events leading to the often excruciating symptoms. Treatment – and management – comprises all aspects from elicitor avoidance to basic emollient skin care, immuno-modulating treatments both topical and systemic, up to the latest advances in kinase inhibitors and biologics.In turn, the book discusses the role of the microbiome and antimicrobial treatments as well as phototherapy, provides dietary recommendations for individuals with food allergies, and explores psychosocial aspects of the disease. Environmental influences are considered with regard to irritants and allergens. All recommendations are based on current national and international guidelines. The complex management strategies for this disease have led to the emergence of educational programs (Eczema Schools), which the authors have developed and promoted at the national and international level. This new revised edition of Atopic Dermatitis - Eczema will be an invaluable asset for dermatologists, allergists, pediatricians and general practitioners, but also for all related health personnel and patient organizations interested in gaining a fuller understanding of this widespread skin disease.
Atopic Dermatitis and Eczematous Disorders
by Donald RudikoffIt is estimated that around 15% of the population suffer from atopic dermatitis or eczematous disorders at some point in their lifetime, causing a significant percentage of visits to dermatologists, primary care physicians, and allergists. Despite much current research interest, the pathophysiology of these disorders and their optimum treatment rem
Atopic Dermatitis and Eczematous Disorders
by Donald Rudikoff Steven R. Cohen Jonathan SilverbergThis updated and revised edition gives the clinician a comprehensive review of the different clinical presentations of eczematous disorders and their associated pathophysiology and treatments. The editors have recruited expert contributors for each topic. There are many color photographs, as well as helpful tables with useful guidelines for treatment, so the dermatologist, the pediatrician, the allergist, and the generalist will all find this work a useful clinical reference for daily practice.FROM REVIEWS OF THE FIRST EDITION‘One of the most thorough references on atopic dermatitis for clinicians’(Doody’s Reviews)‘If you provide care to individuals who are atopic, you will want this volume at your side’(SkinMed)
Atopic Dermatitis: Eczema
by Johannes RingThis book presents the state of the art in research into atopic dermatitis, or atopic eczema, and provides numerous effective practical management recommendations that are grounded in the immense clinical experience of the author. A scientific evidence-based approach to the subject is adopted, progressing from clinical symptoms in different disease stages, molecular genetics, and pathophysiology through to treatment and prevention. All aspects of patient management are covered, including diagnostics, avoidance strategies, emollient therapy, and acute treatment of eczema and itch. Diverse special therapeutic approaches are discussed, ranging from glucocorticoids, topical calcineurin inhibitors, and antimicrobial therapy through to UV therapy, allergen-specific immunotherapy, systemic immunosuppressive therapy, and emerging options. Environmental influences are considered, and there is a focus on the whole human being, with attention to psychosocial aspects of the disease and the benefit of educational programs such as "eczema schools". Atopic Dermatitis will be invaluable for dermatologists, allergists, pediatricians, and general practitioners and informative for other interested persons and sufferers.
Atrial Fibrillation (Fundamental And Clinical Cardiology Ser. #Vol. 50)
by Peter Kowey Gerald V. NaccarelliFilling a gap in the literature, this all-encompassing reference explores the epidemiology, mechanisms, and pathophysiology of atrial fibrillation and compiles the latest diagnostic and treatment practices for patient care. The book summarizes the most recent advances in symptom relief, drug development, device management, and long-term control of
Atrial Fibrillation Ablation, 2011 Update
by Andrea Natale Antonio RavieleThis concise text presents best practices for all aspects of atrial fibrillation ablation as outlined in the new version of the VeniceChart International Consensus document, which is presented in conjunction with the biannual Venice Arrhythmias conference. In addition to discussing the latest in a-fib ablation research, this 2011 update covers all the key areas of therapy and patient management, including:* Techniques and technologies* Procedural endpoints* Patient management pre-, peri- and post-ablation* Prevention and treatment of complications* Definition of success and long-term resultsWith contributions from the world's recognized thought leaders in this field, this book is a highly valuable source of information not only for specialists in electrophysiology, but also for general cardiologists, fellows in cardiology and others interested in this dynamic and increasingly important topic.
Atrial Fibrillation Therapy (Current Cardiovascular Therapy)
by John Camm Gheorghe-Andrei Dan Antoni Bayés LunaThe paradigm for atrial fibrillation (AF) management has changed significantly in recent years. A new era has begun for the prevention of one of the most tremendous complication of AF, stroke. Prevention of ischemic stroke in AF patients with oral anticoagulants represents a huge challenge because of the narrow therapeutic change of these drugs, interindividual and intraindividual variability, and the unsatisfactory time in therapeutically range (TTR) with this type of medication. New guidelines have emerged as a result of new mechanisms for initiation and perpetuation for pharmacotherapy to cure AF and trials with new classes of antithrombotic drugs are ongoing. The treatment of AF is still in its infancy, but recent research is revealing how it can be applied with optimal efficacy. This book assists trainees, recertifying physicians, practicing physicians and other professional staff in internal medicine, cardiology, emergency medicine, and clinical pharmacology to apply new diagnostic tools for selecting the best treatment options for AF patients.
Atrial Fibrillation from an Engineering Perspective (Series in BioEngineering)
by Leif SörnmoProvides an up-to-date overview of techniques developed for acquisition, analysis, and modeling of bioelectrical signals.<P><P> Presents a wide variety of approaches to characterizing and modeling atrial activity.<P> Emphasizes emerging technologies for monitoring of atrial fibrillation in connection with ischemic stroke, interventional ablation procedures, and pharmacological treatment.<P>Atrial Fibrillation from an Engineering Perspective provides an up-to-date overview of techniques developed for acquisition, modeling, and analysis of noninvasive, bioelectrical signals reflecting this common arrhythmia. Special emphasis is put on emerging technologies for monitoring of atrial fibrillation in connection with ischemic stroke, interventional ablation procedures, and pharmacological treatment, applications which all depend on the availability of techniques for detecting and characterizing episodes of paroxysmal atrial fibrillation. Detectors exploring both rhythm and morphology are described, as well as detectors confined to rhythm and better suited for low power implementation. A wide variety of approaches to modeling and characterization of atrial activity are described, emanating from a statistical and deterministic starting points. This book is suitable for graduate students, researchers, and engineers who want a comprehensive treatise of atrial fibrillation from an engineering perspective. It may be used for self-study, as a supplement to courses in signal processing, or as a modern monograph by researchers in the field of atrial fibrillation.
Atrial Fibrillation in Practice
by Gregory Y LipThis book provides a clear, concise, management-orientated approach to atrial fibrillation. It also provides a useful and practical guide to the issues relating to this common cardiac problem, to improve the care and treatment of these patients.