- Table View
- List View
The Neurologic Diagnosis: A Practical Bedside Approach
by Jack N. AlpertAn introductory text that transitions into a moderately advanced, case-based analysis of neurologic disorders and diseases, this book emphasizes how to simplify the process of making a neurologic diagnosis. Medical students and residents are often intimidated by a deluge of data, perception of anatomic complexity, extensive differential diagnoses, and often have no organized structure to follow. Diagnostic methods of general medicine are not applicable. Indeed, neurology is a unique specialty since it requires the intermediary step of an anatomic diagnosis prior to proffering a differential diagnosis. Yet the required knowledge of neuroanatomy need not be profound for the student or resident who will not specialize in neurology or neurosurgery. The Neurologic Diagnosis: A Practical Bedside Approach, 2nd Edition is primarily directed to neurology and neurosurgery residents but it will be useful for medical and family practice residents who will discover that a great percentage of their patients have neurologic symptoms. A one-month neurology rotation out of four years of medical school is not sufficient to make a cogent neurologic diagnosis. The aim of this concise, practical book -- which includes an in-depth video of how to perform a neurologic examination -- is to facilitate the process of establishing a neuroanatomic diagnosis followed by a rigorous analysis of symptoms and signs to reach a well-thought out differential diagnosis. Focused and succinct, this book is an invaluable resource for making a lucid neurologic diagnosis.
The Neurological Emergence of Epilepsy
by Vasia LekkaThis book explores the emergence of epilepsy as a purely neurological disorder, in the second half of the nineteenth century. It focuses on the world's first neurological hospital, the National Hospital for the Paralysed and Epileptic in London, and on its leading figure, John Hughlings Jackson (1835-1911). Through an analysis of the National Hospital's medical records and a historical account of the course of epilepsy until our time, this book presents the nineteenth-century turn towards the scientific study of the human brain and the various political, social, ideological and epistemological implications of this major change. In spite of the recent trend of describing the history of mental illness, mental patients and psychiatric institutions, so far, neurology, epilepsy and epileptic patients have largely remained outside the scope of social historians, historians of medicine and social scientists. This book has the ambition to fill that gap.
The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
by J. J. Volpe Leslie L. Barton Neil R. FriedmanIn this concise book, an international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder. Finally a volume for pediatricians, neurologists, infectious disease specialists and all who care for children.
The Neuron: Cell And Molecular Biology
by Leonard K. Kaczmarek Irwin B. LevitanThe Fourth Edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. <p><p>The book begins with properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neuron generates varied patterns of electrical activity. Covered next are the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The following section examines the biochemical pathways that are linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory. <p><p>The book contains scores of color figures and fully updated chapters; online content packaged exclusively with the Fourth Edition includes detailed animations of neural processes, in-depth supplemental reading, and additional full-color figures and tables.
The Neuronal Microenvironment
by Alan A. Boulton Wolfgang Walz Glen B. BakerThe Neuronal Microenvironment
The Neuropathology of Huntington's Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy
by Udo Rüb Jean Paul G. Vonsattel Helmut Heinsen Horst-Werner KorfThis monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
The Neuropathology of Schizophrenia
by Matthew WilliamsIn the past few decades, neuropathology has witnessed a resurgence. The rise of structural and functional imaging techniques has allowed pathological studies to target regions of special interest as revealed by whole-brain techniques, and the development of comprehensive software packages has facilitated cellular and pathological measurements. Furthermore, a new generation of antibodies and improved staining methods has made the field more accessible to researchers and revealed more detail than could once have been envisaged. Perhaps most important of all has been the sourcing of high-quality tissue through modern, large-scale databases covering multiple tissue banks, removing much of the heterogeneity that had made repeat studies all but impossible. The Neuropathology of Schizophrenia reviews the field following these recent improvements in techniques and contrasting more modern methods against older studies. This book presents the current state of neuropathological knowledge in schizophrenia by means of examination of neuropathology as informed by functional systems. It starts by considering the frontal cortical region, a particularly well-examined region of the brain, before moving through other cortical regions, subcortical pathways and the deep white matter. In addition, potential new routes for investigation are considered, particularly in glial cells.
The Neuropharmacology of Alcohol (Handbook of Experimental Pharmacology #248)
by Kathleen A. Grant David M. LovingerThis volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.
The Neuropharmacology of Nicotine Dependence
by David J.K. Balfour Marcus R. MunafòThe primary purpose of this book and its companion volume The Behavioral Genetics of Nicotine and Tobacco is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While The Behavioral Genetics of Nicotine and Tobacco considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the present book focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of researchand will hopefully prove valuable to those who are developing their own research programmes in this important topic.
The Neurophysics of Human Behavior: Explorations at the Interface of Brain, Mind, Behavior, and Information
by Fred P. Gallo Mark E. FurmanHow do brain, mind, matter, and energy interact? Can we create a comprehensive model of the mind and brain, their interactions, and their influences? Synthesizing research from neuroscience, physics, biology, systems science, information science, psychology, and the cognitive sciences, The Neurophysics of Human Behavior advances a unified theory of
The Neurophysiological Bases of Auditory Perception
by Ray Meddis Enrique Lopez-Poveda Alan R. PalmerThe International Symposium on Hearing is a triennial, highly-prestigious event where world-class scientists present and discuss the most recent advances in the field of hearing research. The symposium focuses on the relationship between auditory physiology, psychoacoustics, and computational modeling. Presented papers range from basic to applied research, and are published in book format. The books from past editions have a large demand by neuroscientists, otolaryngologists, psychologists, and artificial intelligence researchers. This meeting is highly special in that every paper is a plenary session given by invitation by a key, world-class auditory scientist. There are no poster sessions. The editors will have to choose the best 60 papers from approximately 80 submitted abstracts. Priority will be given to hot topics and to papers showing significant advances (this is almost guaranteed, anyhow, by the quality of the speakers). Papers will be submitted by invitation only and invitations will be sent only to the most-significant auditory scientists at present. Furthermore, published papers can be regarded as peer-reviewed because they will be accompanied (in print) by a full discussion between the authors and other conference attendants. This format is identical to that of preceding editions of this symposium and has proven highly successful. A full list of past conference books is given below. We will not know the list of chapters until approximately November 2008, that is 6 months before the conference (May 2009). You can get an idea of the type and format of the chapters by having a look at the books for the last two symposium editions, which were published by Springer.
The Neuropilins: Role and Function in Health and Disease
by Gera Neufeld Ofra KesslerThis book covers basic research topics such as the structure-function relationships of neuropilins and mechanisms of neuropilin-mediated signal transduction, details the most important roles of the neuropilins in developmental biology, and addresses their roles in various conditions such as cancer and various eye diseases. The two neuropilin genes encode scaffold receptors that can bind several different ligands, and also associate with many other receptors and modify their activity. Further, it has been confirmed that they play important roles in the shaping of major organs and tissues such as the nervous system and the vascular system, and that they can modulate immune responses. The book offers a helpful guide for biomedical researchers and all scientists active in the neurosciences, vascular and molecular biology, as well as developmental biology and immunology.
The Neuropsychiatry of Epilepsy
by Bettina Schmitz Michael R. TrimbleResearch into the neuropsychiatry of epilepsy has become a central focus of interest in the last five years. Comorbidity of epilepsy with behavioral problems is now recognized widely, and the neuroscientific basis for such comorbidity is an active area of investigation. With an expanded international team of authors, this fully revised new edition builds on the strengths of its predecessor, examining in detail the subtleties of behavioral changes in patients with seizure disorders and offering both a diagnostic and a management perspective. New chapters cover genetic disorders, the effects of epilepsy on social behavior as viewed through theory of mind, a discussion of the precuneus, the importance and nature of peri-ictal psychiatric symptoms, depression and the interictal dysphoric disorder, and the relationship between antiepileptic drugs and suicide. This new edition is a must for anyone involved in diagnosing or managing epilepsy.
The Neuropsychiatry of Headache
by Mark W. Green Philip R. MuskinWhilst the vast majority of headaches are minor ailments, some patients develop chronic symptoms that have psychiatric dimensions. These symptoms can be immensely challenging to manage and can have a serious impact on the patient's quality of life. The relationship between headache and psychiatric disease is often rationalized as cause and effect; however, the interplay between the two is complex. Management of each of the co-morbid disorders affects the other one in positive and/or negative ways. The Neuropsychiatry of Headache details the current concepts of various headache conditions and the psychiatric syndromes; topics covered include migraine, mood disorders, medication overuse and personality disorders. Headache specialists, neurologists, psychiatrists, neuropsychiatrists and neuropsychologists will find this an invaluable resource for understanding and co-managing these conditions.
The Neuropsychological Analysis of Problem Solving
by LuriaFor any of us, problem solving is a daily event. For some, it is a major task. This historical book puts to use neuropsychological methods to analyze the process of problem solving. Experience shows that the process is psychologically so complicated that standard methods established in pedagogy and psychology are insufficient to precisely determine individual factors hindering effective problem solving.The authors present techniques for rehabilitation training which could compensate for the impairments observed in individual cases. Luria's work has transformed rehabilitation training, enabling the evaluation of rehabilitation principles and methods.Luria's thinking and conceptual style reflect his genius and rich understanding of brain-behavior relationships. As those who have read it agree, Luria demonstrates remarkable insight with his complex analysis and his qualitative analysis is ""breathtaking.
The Neuropsychology Toolkit
by Richard L. WanlassThis book provides information, guidelines, and materials to help future neuropsychology supervisees identify, understand, and avoid some of these problems and pitfalls. Also included are a neuropsychological questionnaire, short- and long-report formats, and sample statements that can be used to help with wording sections of the report that are particularly challenging to write.
The Neuroscience of Clinical Psychiatry: The Pathophysiology Of Behavior And Mental Illness
by Edmund HigginsBridge the gap between neuroscience and mental illness/mental health with this straightforward and reader-friendly resource! The Neuroscience of Clinical Psychiatry, 3rd Edition is a highly readable, in-depth text ideal for residents studying for boards, practicing psychiatrists, and any mental health professional seeking an overview of the neuroscience revolution. Focusing on the basic neuroscientific concepts underlying normal behavior and commonly encountered disorders, Dr. Edmund S. Higgins and Dr. Mark S. George make complex information enjoyable, relevant, and easy to understand, ensuring that this Third Edition continues to be a trusted source of information on the neurologic underpinnings of psychiatric disorders.
The Neuroscience of Everyday Life: An Applied Guide for Health Sciences Students
by Winnie Dunn Dawn M. Nilsen Timothy J. Wolf Lorie Gage RichardsBy weaving vignettes and case studies throughout, this fascinating and original textbook provides an accessible primer not only on the key principles of neuroscience but, crucially, how they may manifest in the everyday lives of people with neurological conditions.Each chapter begins with the story of a person or family, including a description of what they want to do in their everyday life, before presenting the neuroscientific principles that underlie this person’s situation. Rather than a technical book about neuroanatomy, physiology, or pathology, the spotlight is on understanding the way that neurological differences impact a person’s life. Through focusing on a particular condition, each chapter highlights a different aspect of the nervous system, and what happens when things change. A wide range of topics are covered, from conditions such as Parkinson’s, dementia, MS, and autism, to conditions resulting from traumatic events such as spinal cord injuries, stroke, and chronic pain. The goal of the book is to trace a thread from neuroscience to how the nervous system affects active participation in daily activities. This approach gives students and professionals a thorough and informed grounding to support problem-solving in practice, improving evidence-based assessment, interventions, and outcomes.Following current evidence-based teaching practices, this text emphasizes engaged teaching/learning methods throughout each chapter to encourage students’ own active discovery. This ground-breaking text will be essential reading for any health science students as well as professionals in practice.
The Neuroscience of Hallucinations
by Delphine Pins Pierre Thomas Renaud Jardri Arnaud CachiaHallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: Hallucinations in the healthy individual. A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling. Molecular mechanisms of hallucinogenic drugs. Structural and functional variations in the hallucinatory brain in schizophrenia. The neurodevelopment of hallucinations. Innovations in brain stimulation techniques and imaging-guided therapy. Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.
The Neuroscience of Handwriting: Applications for Forensic Document Examination (International Forensic Science And Investigation Ser.)
by Michael P. Caligiuri Linton A. MohammedThe Daubert trilogy of U.S. Supreme Court cases has established that scientific expert testimony must be based on science grounded in empirical research. As such, greater scrutiny is being placed on questioned document examination generally, and handwriting comparison in particular. Bridging the gap between theory and practice, The Neuroscience of
The Neuroscience of Mindfulness Meditation
by Yi-Yuan TangThis book presents the latest neuroscience research on mindfulness meditation and provides guidance on how to apply these findings to our work, relationships, health, education and daily lives. Presenting cutting-edge research on the neurological and cognitive changes associated with its practice Tang aims to explain how it reaps positive effects and subsequently, how best to undertake and implement mindfulness practice. Mindfulness neuroscience research integrates theory and methods from eastern contemplative traditions, western psychology and neuroscience, and is based on neuroimaging techniques, physiological measures and behavioural tests. The Neuroscience of Mindfulness Meditation begins by explaining these foundations and then moves on to themes such as the impact of personality and how mindfulness can shape behaviour change, attention and self-control. Finally, the book discusses common misconceptions about mindfulness and challenges in future research endeavours. Written by an expert in the neuroscience of mindfulness this book will be valuable for scholars, researchers and practitioners in psychotherapy and the health sciences working with mindfulness, as well as those studying and working in the fields of neuroscience and neuropsychology.
The Neuroscience of Psychedelics: The Pharmacology of What Makes Us Human
by Genís Ona• Examines the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, and MDMA• Explains the physiological mechanisms behind visionary effects, including what is happening in the brain and how each psychedelic is processed by the body• Shares safe strategies for using psychedelics, including harm-reduction techniques, and looks at where the future of psychedelic therapies is likely to goWith the widespread legalization of marijuana and the increasing use of psychoactives in controlled therapy settings, further research and understanding of psychedelics is now possible. Yet while individual accounts of their use abound, exactly what&’s happening to the brain and body when using these substances is still not widely understood.Longtime pharmacological researcher Genís Ona presents a comprehensive look at the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, tropane alkaloids, and MDMA. Exploring how psychedelics work within the brain, Ona shares results from his extensive research to reveal the physiological mechanisms that allow these molecules to have their visionary effects, explaining what is happening at the receptor level as well as the &“cascade&” effects that differ from substance to substance. He examines how the body processes each substance, describing how each psychedelic is released, absorbed, distributed, metabolized, and eliminated. He also details possible dangerous interactions between these substances and other drugs as well as their potential toxicity.Although his main focus is the biological and neurological effects of psychedelics, Ona also explores the mystical and spiritual dimension of psychedelic use, particularly as practiced in Indigenous traditions, showing how they enable access to a profound spiritual territory. He shares safe strategies for using psychedelics and looks at where the future of psychedelic therapies is likely to go, with an emphasis on ensuring that traditional knowledge is respected, honored, and protected.
The Neuroscience of Psychotherapy: Healing the Social Brain (IPNB #0)
by Louis CozolinoA new edition of the classic text that links neuroscience and human behavior in a therapeutic context. This groundbreaking book explores the revolution in psychotherapy that brought an understanding of the social nature of people’s brains into a therapeutic context. Louis Cozolino is a master at synthesizing neuroscience and demonstrating how it applies to psychotherapy practice. Here, he argues that all forms of psychotherapy are successful to the extent to which they enhance change in relevant neural circuits. Beginning with an overview of the intersecting fields of neuroscience and psychotherapy, this book delves into the brain’s inner workings, from basic neuronal building blocks to complex systems of memory, language, and the organization of experience. In this updated edition, readers will also find new content on the evolutionary foundations of psychotherapy; the necessity of gaining broad perspectives on mind, brain, and culture in clinical training; the importance of interpreting research with the human brain’s biases in mind; the debatable applicability of Eurocentric perceptions of “self”; and more.
The Neurosciences and the Practice of Aviation Medicine
by Anthony N. NicholsonThis book brings the neurosciences to operational and clinical aviation medicine. It is concerned with the physiology and pathology of circadian rhythmicity, orientation, hypotension and hypoxia, and with disorders of the central nervous system relevant to the practice of aviation medicine. The chapters on circadian rhythmicity and orientation deal with the impaired alertness and sleep disturbance associated with desynchrony and with the effects of linear and angular accelerations on spatial awareness. Hypotension and hypoxia cover cerebral function during increased gravitational stress, clinical aspects of exposure to acute hypoxia, the mild hypoxia of the cabin of transport aircraft, adaptation and acclimatization to altitude and decompression at extreme altitudes and in space. Disorders of particular significance to the practice of aviation medicine such as excessive daytime sleepiness, epilepsy, syncope, hypoglycaemia, headache and traumatic brain injury are covered, while neuro-ophthalmology, the vestibular system and hearing also receive detailed attention. The potentially adverse effects of the aviation environment and of disorders of the nervous system are brought together, and the text covers the neurological examination as it relates to aircrew and explores current management and therapeutics. The Neurosciences and the Practice of Aviation Medicine is an essential work for those involved in the practice of aviation medicine where familiarity with the effects of the aviation environment on the nervous system and understanding the pathophysiology of relevant clinical disorders are of prime concern. The authors from leading centres of excellence are physiologists concerned with the aviation environment and physicians involved in the day-to-day practice of medicine. They bring to this authoritative text wide experience and expertise in both the experimental and clinical neurosciences.
The Neuroscientist Who Lost Her Mind: My Tale of Madness and Recovery
by Barbara K. Lipska Elaine McArdleAs a deadly cancer spread inside her brain, leading neuroscientist Barbara Lipska was plunged into madness—only to miraculously survive with her memories intact. In the tradition of My Stroke of Insight and Brain on Fire, this powerful memoir recounts her ordeal and explains its unforgettable lessons about the brain and mind. In January 2015, Barbara Lipska—a leading expert on the neuroscience of mental illness—was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, just as her doctors figured out what was happening, the immunotherapy they had prescribed began to work. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity. In The Neuroscientist Who Lost Her Mind, Lipska describes her extraordinary ordeal and its lessons about the mind and brain. She explains how mental illness, brain injury, and age can change our behavior, personality, cognition, and memory. She tells what it is like to experience these changes firsthand. And she reveals what parts of us remain, even when so much else is gone.