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The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications
by Enrique Zudaire Frank CuttittaAngiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases. These extraordinary advancements have been built upon a vast array of diverse analytical techniques developed globally throughout the field. Over the years, these methods have evolved to suit the specific needs of different researchers and experimental scenarios, resulting in a myriad of technical variants of basic assay approaches. "The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications" is an up-to-date comprehensive textbook on angiogenesis and lymphangiogenesis techniques and applications. This volume is designed to embody the collective works of experts in the clinical as well as the basic research arenas who have significantly contributed to the development and application of techniques in all areas of angiogenesis and lymphangiogenesis. Each chapter introduces and discusses one or a group of closely related techniques and convey step-by-step protocol information and detailed technical guidance to the reader. Emphasis has been placed on explanatory illustrations, critical technical steps as well as divulging information on the benefits and caveats of specific practices related to the methods discussed. This manual is intended to serve as a written guide for both newcomers and established professionals in the field.
Textbook of Assisted Reproduction
by Gautam Nand Allahbadia Baris Ata Steven R. Lindheim Bryan J. Woodward Bala BhagavathGroundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples around the world. The book aims to cover all aspects of assisted reproduction. Particular attention is given to topics such as the assessment of infertile couples; assisted reproductive techniques (ARTs) including ovulation induction, intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (clinical and laboratory aspects); reproductive genetics; and obstetric and perinatal outcomes.
Textbook of Assisted Reproductive Techniques: Two Volume Set
by David K. Gardner Ariel Weissman Colin M. Howles Zeev ShohamAlready established as a classic comprehensive reference for the whole team at the IVF clinic, this new edition has been extensively revised, with the addition of several important new contributions on laboratory ( including advanced sperm selection techniques for ICSI, human embryo biopsy procedures, oocyte activation, managing an oocyte bank, artificial gametes, and epigenetics) as well as on clinical topics (including GnRH agonist triggering, segmentation of IVF treatment, uterus transplantation, and risk and safety management). As previously, methods, protocols, and techniques of choice are presented by eminent contributors internationally.
Textbook of Assisted Reproductive Techniques: Volume 1: Laboratory Perspectives (Reproductive Medicine And Assisted Reproductive Techniques Ser.)
by David K. Gardner Ariel Weissman Colin M. Howles Zeev ShohamEstablished as a definitive reference for the IVF clinic, the fifth edition has been extensively revised, with the addition of several important new contributions on laboratory topics, including advanced sperm selection techniques for ICSI, human embryo biopsy procedures, oocyte activation, managing an oocyte bank, artificial gametes, and epigenetics. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Textbook of Assisted Reproductive Techniques: Volume 1: Laboratory Perspectives (Reproductive Medicine And Assisted Reproductive Techniques Ser.)
by David K. Gardner Ariel Weissman Colin M. Howles Zeev ShohamEstablished as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on laboratory topics, including KPIs for the IVF laboratory, Quality control in the cloud, Artificial Intelligence, AI in gamete and embryo selection, Demystifying vitrification, Microfluidics, Gene editing, Disaster management, and Early human embryo development revealed by static imaging. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Textbook of Assisted Reproductive Techniques: Volume 2: Clinical Perspectives (Reproductive Medicine And Assisted Reproductive Techniques Ser.)
by David K. Gardner Ariel Weissman Colin M. Howles Zeev ShohamEstablished as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on clinical topics, including The use of digitalization and precision medicine in the IVF clinic, The environment and reproduction, The use of gonadotropin-releasing hormone agonists and the efficiency of IVF, Controlled ovarian stimulation for freeze-all cycles, Immunology in ART, Home monitoring of ART cycles, Luteal-phase support in ART, The POSEIDON stratification of ‘low prognosis’ patients in ART, Controlled ovarian stimulation for low responder patients, Adjuvants for poor responders, Innovative therapies in diminished ovarian reserve and primary ovarian insufficiency patients, and Fertility options for transgender and nonbinary individuals. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Textbook of Assisted Reproductive Techniques: Volume 2: Clinical Perspectives (Reproductive Medicine And Assisted Reproductive Techniques Ser.)
by David Gardner Ariel Weissman Zeev Shoham Colin HowlesEstablished as a definitive reference for the IVF clinic, the fifth edition has been extensively revised, with the addition of several important new contributions on clinical topics, including GnRH agonist triggering, segmentation of IVF treatment, uterus transplantation, and risk and safety management. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Textbook of Atopic Dermatitis (Series in Dermatological Treatment)
by Sakari Reitamo Thomas A. Luger Martin SteinhoffAtopic dermatitis or atopic eczema is an extremely common skin disease characterized by red patches, dry, scaling or crusting skin, and intense itch. It frequently develops in children during the first year of life and can become severe, with a consequently major impact on health-related quality of life. This text from international experts draws t
Textbook Of Ayurveda: Fundamental Principles, Volume One
by Vasant Lad Kevin Curry Robert E. Svoboda Shawn O'Connor Carlos LunaIn his Ayurvedic Studies Program, Vasant Lad teaches Ayurveda as a science of moment-to-moment living. Each lecture that he gives flows from his own heart in a river of healing wisdom. This textbook conveys the philosophical and fundamental principles of Ayurveda in a dynamic and inspirational way, providing a detailed foundation upon which to pursue deeper knowledge.
Textbook of Basic Nursing (10th Edition)
by Mary T. Kowalski Caroline Bunker RosdahlThe new, revised edition of this extremely popular all-in-one text for the practical/vocational nursing curriculum has everything to meet the needs of students and instructors. The text, which is part of Lippincott,,s Pathways for LPN/LVN Education Series, contains information on all the critical areas in the curriculum%Anatomy & Physiology, Fundamentals, Skills, Adult Health, Growth and Development, Mental Health, Maternity and Pediatrics, and Geriatric Considerations. Based heavily on the NCLEX-PN framework, this highly-visual new edition features short chapters with easily digestible content including review questions, features, and alerts for reinforcement of important content. The text is accompanied by a robust student Workbook and a comprehensive, turn-key ancillary program to help teachers teach and students learn! A special feature of the new edition is the inclusion of NCLEX-PN Alerts, which highlight critical NCLEX-relevant content in each key area, and a voluminous Test Generator that more than doubles the number of questions in the previous edition.
Textbook of Biochemistry: With Clinical Correlations, Seventh Edition
by Thomas M. DevlinThis book presents a clear and precise discussion of the biochemistry of eukaryotic cells, particularly those of mammalian tissues, relates biochemical events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of abnormal biochemical processes in human disease. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to human diseases.
Textbook of Breast Cancer: A Clinical Guide to Therapy
by Gianni Bonadonna Gabriel N Hortobagyi Pinuccia ValagussaWith the current advances in chemotherapy and hormonal drugs for breast cancer, as well as in surgical techniques and procedures, a revised edition of this popular textbook has become increasingly necessary. Completely overhauling the existing material, the editors of this important work have provided a full update of the area, focusing in particul
Textbook of Cardiorenal Medicine
by Peter A. McCullough Claudio RoncoThis textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings together experts at the nexus between cardiovascular and renal medicine to provide an exception reference to educate in this critical area of modern medicine. It describes how the heart and kidneys are inextricably linked via hemodynamic, neural, hormonal and cellular signaling systems and, concentrating on disease-based coverage, goes on to review emerging concepts in epidemiology, pathogenesis, screening, diagnosis and the management of cardiorenal syndromes, all extensively illustrated and containing features to support scholarship in the field. Textbook of Cardiorenal Medicine provides consistent chapter organization, clear design and engaging text to define the diagnosis, treatment, intervention and surgical aspects of the full range of conditions encountered within this area of medicine. It is therefore an essential resource to all involved in the management of cardiorenal disease.
Textbook of Cardiovascular Intervention
by Craig A. ThompsonThe field of interventional cardiology and interventional vascular medicine now comprises the dominant diagnostic and therapeutic field within cardiovascular medicine, and continues to grow in terms of patients managed and physicians trained. The Textbook of Cardiovascular Intervention is intended to provide a modern, comprehensive and practical text on interventional cardiology for the current, rapidly evolving practice environment. It is written by a group of worldwide experts in the field and will appeal to fellows, residents and physicians in cardiology, interventional cardiology, cardiothoracic and vascular surgery, vascular and endovascular medicine, neurointerventional radiology and surgery, emergency medicine and intensive care.
Textbook of Catheter-Based Cardiovascular Interventions: A Knowledge-based Approach
by Peter LanzerThis book is a fully updated and revised second edition of a highly successful text in which a new concept of knowledge mining, based on explication and transfer of interventional knowledge of experts, has been implemented. The dedicated training program that is set out will serve the needs of all interventional operators, whether cardiologists, vascular surgeons, vascular specialists, or radiologists, enabling them to achieve a consistent expert level across the entire broad spectrum of catheter-based interventions. Operator skills – and in particular decision-making and strategic skills – are the most critical factors for the outcome of catheter-based cardiovascular interventions. Currently, such skills are commonly developed by the empirical trial and error method only. The explicit teaching, training, and learning approach adopted in this book permits the rapid transfer of interventional knowledge and enables individual operators to negotiate steep learning curves and acquire complex skills in a highly efficient manner. It will thereby offer invaluable assistance in meeting successfully the challenges of modern cardiovascular care.
Textbook of Cell Signalling in Cancer
by Jacques RobertThis book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis. This comprehensive reference text is based on the master's courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.
Textbook of Chemical Peels: Superficial, Medium, and Deep Peels in Cosmetic Practice (Series in Cosmetic and Laser Therapy)
by Philippe DeprezChemical peels have returned to the forefront of the practitioner's armamentarium and are popular because they offer nearly immediate results. The Textbook of Chemical Peels is the definitive guide to all types of chemical peel treatments. It covers the practical application and scientific background for a wide variety of chemical peels. The book reflects the new classification of peels as a medical, rather than cosmetic, treatment and helps providers by making chemical peel formulas easier, safer, and quicker to use. The book covers the appropriate selection of peels to treat the face, scalp, neck, hands, body, and forearms. It also discusses the use of peels to treat aging skin, stretch marks, scars, melasma, chloasma, acne, postinflammatory hyperpigmentation, and scalp keratoses.The mechanism of action, indication, application, and results are discussed for a variety of chemical peels including alpha hydroxy acids, trichloroacetic acid, salicylic acid, resorcine, and phenols. Also covered are any contraindications, precautions, and safety issues. This edition includes new material on adjunctive procedures such as microneedling and mesotherapy as well as new information on mosaic peels.Treatment prior to and following the peel are also discussed in detail, and a full chapter is devoted to discussing complications associated with chemical peels. The book incorporates color clinical photographs throughout as well as descriptive tables summarizing key information. Based on the author’s extensive experience in both research and practice, this updated reference is an invaluable guide to all providers involved with chemical peel treatments.
Textbook of Clinical Embryology
by Kevin Coward Dagan WellsThe success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook - inspired by the postgraduate degree program at the University of Oxford - guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
A Textbook of Clinical Embryology
by Eliezer GirshPersonnel working in assisted reproductive technology often lack the opportunities for dedicated training in the specialized techniques and technologies required for the procedures. As such, success in the form of live birth rates can range from over 50% to less than 10% per treatment cycle. This comprehensive introductory textbook is an essential resource for trainee embryologists, medical students and nurses. The recent revolutions in biotechnology and molecular biology involved in delivering assisted reproductive services are thoroughly discussed. Basic knowledge such as the development and physiology of both male and female reproductive systems is covered, with practical aspects of IVF including gamete and embryo manipulation, cryopreservation and genetic testing explained in detail. A full description of the optimal structure and management of the IVF laboratory is given, helping ensure procedures are safe and effective. Extensive and highly detailed colour illustrations bring the content to life and aids readers in their understanding.
Textbook of Clinical Epidemiology: For Medical Students
by Chongjian Wang Fen LiuThis book is a comprehensive and practical introduction of clinical epidemiology for students and practitioners. It covers both the basic principles and concepts of clinical epidemiology as well as its applications in various medical disciplines.It covers how to design, conduct, and interpret clinical studies using methods such as bias analysis, confounding control, causality assessment, diagnosis evaluation, prognosis prediction treatment comparison, and meta-analysis in this book. It also introduces how to apply these skills to real-world scenarios through case studies and examples that provide a fresh perspective on familiar topics. This book is a useful textbook for graduate and undergraduate students in medical schools, including MBBS (Bachelor of Medicine and Bachelor of Surgery) student.
Textbook of Clinical Gastroenterology and Hepatology
by C. J. Hawkey Jaime Bosch Joel E. Richter Guadalupe Garcia-Tsao Francis K. L. ChanWhereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.
Textbook of Clinical Management of Club Drugs and Novel Psychoactive Substances: NEPTUNE Clinical Guidance
by Dima Abdulrahim Owen Bowden-JonesThere are global concerns about the proliferation and misuse of club drugs and novel psychoactive substances, yet we know little about their harms and research on clinical management and treatment remains limited. This book fills the knowledge gap by providing a detailed overview of the research evidence available to date. The book provides a framework that allows readers to understand this large number of new drugs, using classifications based on primary psychoactive effect. Within this framework, the book provides detailed reviews of the more commonly used drugs. Each chapter explores pharmacology, patterns and mode of use, acute and chronic harms, and clinical interventions supported by research evidence. An invaluable resource for clinical staff, this book will support clinicians working in the emergency department, substance misuse and addiction services, mental health services, primary care, sexual health services and more. It will also be of interest to academics and those developing drug policy.
Textbook of Clinical Neurology
by J.B.M. Kuks J. W. SnoekThis textbook is in line with the latest international thinking, guidelines and research findings in the field of neurology. The treatment guidelines used in the Netherlands and Belgium have been taken into account, thus making it a useful source of information in training and clinical practice. The reader is guided from basic concepts to complex physiology. The first nine chapters are devoted to the basic neurological sciences and provide a glimpse of clinical practice. The ensuing seventeen clinical chapters are based on the illness model, thus giving the reader an overview of a large number of neurological disorders. Each chapter begins with a case study which provides a practical context for the theory. The textbook also includes many tables and diagrams to clarify the concepts discussed. The Textbook of Clinical Neurology is also available online. Readers will find the entire content on the website, along with test questions, case studies, guidelines and other additional material. The textbook is designed for use in medical and paramedical training and is also suitable for programmes in nursing, human movement sciences, and medical biology. It serves as a reference for doctors and physiotherapists in clinical practice.
Textbook of Clinical Neurology
by J.B.M. Kuks J.W. Snoek B. Jacobs C.O. Martins JarnaloThis textbook is designed for use in medical and paramedical training and is also suitable for programmes in nursing, human movement sciences, and medical biology. It serves as a reference for doctors and paramedics such as physiotherapists in clinical practice. This 2nd edition was written parallel with the 19th edition of the Dutch textbook, that has been used in medical and paramedical curricula in the Netherlands and Belgium for many years. The authors used their broad experience in medical education and encorporated many comments of students to come to a practice-based textbook for the education of undergraduate students and young residents in Neurology. It is in line with the most recent international thinking, guidelines and research findings in the field of neurology. The treatment guidelines used in Europe have been taken into account. The reader is guided from basic concepts to complex physiology. The first eleven chapters are devoted to the basic neurological sciences and provide a glimpse of clinical practice. The ensuing nineteen clinical chapters are based on the illness model, thus giving the reader an overview of a large number of neurological disorders. Each chapter starts with a case study which provides a practical context for the theory. The textbook also includes many tables and diagrams to clarify the concepts discussed. The Textbook of Clinical Neurology is also available online. Readers will find the entire content on the website, along with test questions, case studies, guidelines and other additional material.
Textbook of Clinical Otolaryngology
by Abdulsalam Al-Qahtani Hassan Haidar Aisha LaremThis textbook provides a comprehensive overview of the state of the art in otolaryngology, discussing all the newly advances in the subspecialties of head and neck, plastics, otology, laryngology, rhinology and pediatrics, and also addressing topics like allergy, sleep medicine, trauma, and the fundamentals of systemic diseases that frequently manifest in the head and neck region. The book is divided into 9 sections, presenting the recent literature concerning all the subspecialties in otolaryngology and providing the information necessary for readers to gain an understanding of the field of otolaryngology. Each chapter includes definitions, key points and take-home messages, to aid learning. Throughout the book, tips and key features are highlighted with boxes, tables and figures, which the reader can refer back to for quick revision. Above all, the book enables medical students, residents and junior specialists in the field of ENT to develop their learning and surgical skills.