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Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation

by Stephen J. Forman Robert S. Negrin Joseph H. Antin Frederick R. Appelbaum

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Thomas' Hematopoietic Cell Transplantation

by Robert S. Negrin Stephen J. Forman Karl G. Blume Frederick R. Appelbaum

This outstanding reference source on bone marrow transplantation has become recognised as the bible in the field. This fourth edition has been fully revised to reflect latest developments, and now features over 500 illustrations, including a colour plate section. The need for this new edition cannot be overstated - more than 13,000 new cases per year of haematopoietic stem cell transplantation have been reported to the International Bone Marrow Transplant RegistryThe original editor, Donnall Thomas, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases.The book also now includes a fully searchable CD with PDFs of the entire content.

Thomas' Hematopoietic Cell Transplantation, 2 Volume Set

by Stephen J. Forman Frederick R. Appelbaum Joseph H. Antin Robert S. Negrin

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making New companion website with full searches capabilities and downloadable figures

Thomas Percival’s Medical Ethics and the Invention of Medical Professionalism: With Three Key Percival Texts, Two Concordances, and a Chronology (Philosophy and Medicine #142)

by Laurence B. McCullough

This book provides the first comprehensive, historically based, philosophical interpretations of two texts of Thomas Percival’s professional ethics in medicine set in the context of his intellectual biography. Preceded by his privately published and circulated Medical Jurisprudence of 1794, Thomas Percival (1740-1804) published Medical Ethics in 1803, the first book thus titled in the global histories of medicine and medical ethics. From his days as a student at the Warrington Academy and the medical schools of the universities of Edinburgh and Leyden, Percival steeped himself in the scientific method of Francis Bacon (1561-1626). McCullough shows how Percival became a Baconian moral scientist committed to Baconian deism and Dissent. Percival also drew on and significantly expanded the work of his predecessor in professional ethics in medicine, John Gregory (1724-1773). The result is that Percival should be credited with co-inventing professionalism in medicine with Gregory. To aid and encourage future scholarship, this book brings together the first time three essential Percival texts, Medical Jurisprudence, Medical Ethics, and Extracts from the Medical Ethics of Dr. Percival of 1823, the bridge from Medical Ethics to the 1847 Code of Medical Ethics on the American Medical Association. To support comparative reading, this book provides concordances of Medical Jurisprudence to Medical Ethics and of Medical Ethics to Extracts. Finally, this book includes the first Chronology of Percival’s life and works.

Thomas S. Szasz: The Man and His Ideas

by Jeffrey A. Schaler Henry Zvi Lothane Richard E. Vatz

As it entered the 1960s, American institutional psychiatry was thriving, with a high percentage of medical students choosing the field. But after Thomas S. Szasz published his masterwork in 1961, The Myth of Mental Illness, the psychiatric world was thrown into chaos. Szasz enlightened the world about what he called the “myth of mental illness.” His point was not that no one is mentally ill, or that people labeled as mentally ill do not exist. Instead he believed that diagnosing people as mentally ill was inconsistent with the rules governing pathology and the classification of disease. He asserted that the diagnosis of mental illness is a type of social control, not medical science. The editors were uniquely close to Szasz, and here they gather, for the first time, a group of their peers—experts on psychiatry, psychology, rhetoric, and semiotics—to elucidate Szasz’s body of work. Thomas S. Szasz: The Man and His Ideas examines his work and legacy, including new material on the man himself and the seeds he planted. They discuss Szasz’s impact on their thinking about the distinction between physical and mental illness, addiction, the insanity plea, schizophrenia, and implications for individual freedom and responsibility. This important volume offers insight into and understanding of a man whose ideas were far beyond his time.

Thompson & Thompson Genetics and Genomics in Medicine, 9th Edition

by Ronald Doron Cohn Stephen W. Scherer Ada Hamosh

First published in 1966, Thompson and Thompson Genetics and Genomics in Medicine has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over. Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveries―such as the functional roles of non-coding RNAs, chromatin regulation and epigenetics―latest technologies, and new diagnoses they are enabling. Under an expanded title, this ninth edition has been completely revised by a new editorial team overseeing a large cadre of contributing authors. Support groups have also assisted in updating illustrations featuring beautiful images of those living with genetic conditions. - Comprehensive coverage of: genomes in biology and medicine; copy number and structural genomic variation; novel discoveries; latest technology; and new genetic diagnoses - Over 40 clinical case studies, capturing the latest challenges of variable expression, pleiotropy, and complex disorders through new diagnostic strategies - Full-color text, illustrations, updated line diagrams, and clinical photos - End-of-chapter questions and comprehensive answers to challenge the reader to consolidate the material into practice and prepare for examination - An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud - Updated and new clinical cases, supported with photography by the not-for-profit organization, Positive Exposure - New content on growing role of sequencing and novel functional assays in diagnosis and screening of genetic conditions - New chapter on Epigenetics - Clearer and more precise terminology, in response to contemporary and evolving guidelines - New sections describing the use (and need for) genetic information from diverse populations, including unique indigenous and founder populations, for diagnosis and management.

Thompson & Thompson GENETICS IN MEDICINE

by Robert L. Nussbaum Roderick R. Mcinnes Huntington F. Willard

Through six editions, Thompson & Thompson's Genetics in Medicine has been a well-established favorite textbook on this fascinating and rapidly evolving field, integrating the classic principles of human genetics with modern molecular genetics to help you understand a wide range of genetic disorders. The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex concepts more easily. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics. Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included.

Thoracic Imaging: Illustrated Clinical Cases, Second Edition (Thieme Publishers Ser.)

by Sue Copley David Hansell Jeffrey Kanne

The chest radiograph is a ubiquitous, first-line investigation and accurate interpretation is often difficult. Radiographic findings may lead to the use of more sophisticated imaging techniques, such as multidetector computed tomography (MDCT) and positive emission tomography. Containing 100 challenging clinical cases and illustrated with superb, h

Thoracic Imaging: A Core Review

by Stephen Hobbs Christian Cox

Prepare for success on the thoracic imaging component of the radiology Core Exam! Thoracic Imaging: A Core Review, 2nd Edition, is an up-to-date, practical review tool written specifically for the Core Exam. This helpful resource contains 300 image-rich, multiple-choice questions with detailed explanations of right and wrong answers, fully revised content, and additional eBook questions to ensure you’re ready for the Core Exam or recertification exam.

Thoracic Outlet Syndrome

by Dean M. Donahue Julie Ann Freischlag Karl A. Illig Peter I. Edgelow Robert W. Thompson Sheldon E. Jordan

Thoracic Outlet Syndrome is an essential reference for physicians involved in the diagnosis, referral and treatment of the condition. Thoracic outlet syndrome (TOS) is made up of a constellation of problems resulting from pathology at the thoracic outlet in the neck. Busy specialty practice see multiple affected patients in every clinic, however TOS can often be difficult to diagnosis. This book explores all possible ancillary care issues surrounding this complex condition, including rehabilitation, disability, natural history, and medicolegal issues, and aims to stimulate research, discussion, and a sense of community between professionals involved in this area. Vascular, thoracic, and neurosurgeons, neurologists, psychiatrists and psychologists, physical therapists, occupational medicine specialists, and pain specialists alike, will find this book to be a must have for successfully treating, referring and diagnosing TOS in clinical practice.

Thoracic Outlet Syndrome

by Karl A. Illig Robert W. Thompson Julie Ann Freischlag Dean M. Donahue Sheldon E. Jordan Ying Wei Lum Hugh A. Gelabert

This extensively revised edition is an essential reference for physicians involved in the diagnosis, referral and treatment of the thoracic outlet syndrome (TOS). TOS is made up of a constellation of problems resulting from pathology at the thoracic outlet in the neck. Busy specialty practice sees multiple affected patients in every clinic, but TOS can often be difficult to diagnosis. Thoracic Outlet Syndrome explores all possible ancillary care issues surrounding this complex condition, including rehabilitation, disability, natural history and medicolegal issues, and aims to stimulate research, discussion and a sense of community between professionals involved in this area. Vascular and thoracic surgeons, neurosurgeons, neurologists, psychiatrists and psychologists, physical therapists, occupational medicine specialists and pain specialists will find this book a must read for successful treatment, referral and diagnosis of TOS in clinical practice.

Thoracic Radiology: A Guide for Beginners

by Michele Anzidei Iacopo Carbone

This book offers a comprehensive overview of all major pathologic conditions involving the lung and mediastinum and the related diagnostic procedures. Oncologic and non-oncologic conditions are reviewed and described in detail, featuring, besides normal anatomy, also high quality images from several modalities (including X-ray, CT, MR and PET), as well as b/w and color illustrations and line drawings. Complications associated with surgical and oncological treatments are also presented in detail with extensive imaging examples. The book provides a thorough coverage of the topic of thoracic imaging, yet considering a concise and synthetic approach essential to optimal learning. The book will be a useful reference guide for the everyday clinical practice of young radiologists, residents and medical students.

Thoracic Surgery: Cervical, Thoracic and Abdominal Approaches

by Claudiu E. Nistor Steven Tsui Kaan Kırali Adrian Ciuche Giuseppe Aresu Gregor J. Kocher

This book provides a guide to the anatomy and the surgical techniques required in thoracic and cardiothoracic surgery. It discusses the advantages and disadvantages of certain surgical procedures in relation to the lymphatic system, thyroid gland, chest wall and parathyroid glands, as well as pulmonary endarterectomy. Further, it addresses intraoperative and postoperative complications, and explores newer fields like microthymectomy, microlobectomy, and pain management for thoracic surgery patients. Providing an update on the latest advances in thoracic surgery, it appeals to general, thoracic, cardiothoracic, and cardiovascular surgeons. It also offers trainees insights into the foundation of the techniques and the relevant anatomy.

Thoracic Surgery: 50 Challenging Cases

by Wickii Vigneswaran

In Thoracic Surgery: 50 Challenging Cases, editor Wickii T. Vigneswaran has selected 50 challenging cases presented by leading thoracic surgeons. Each case highlights a unique situation from which other surgeons can learn. The selection of Cases includes patients with diagnostic challenges, unconventional and innovative solutions, unexpected findings, and new techniques to treat old problems. The discussions after each case provide a useful starting point for further inquiry. Amply illustrated, this book reflects the wisdom and experience of world leaders in thoracic surgery and teaches junior surgeons how to approach the key thoracic surgical procedures, and how to manage in unexpected and difficult situations. This is a Masterclass in thoracic surgery.

Thoracic Surgery Clerkship: A Guide for Senior Medical Students (Contemporary Surgical Clerkships)

by Thomas Ng Travis Geraci

This quick-reference guide is the first book written specifically for the many third- and fourth-year medical students rotating on the thoracic surgery service. The book focuses on the diagnosis and management of the most common pathologic entities. Each chapter covers history, physical examination, imaging, and common diagnoses. For each diagnosis, the book sets out the typical presentation, options for non-operative and operative management, and expected outcomes. Chapters include key illustrations, quick-reference charts, tables, diagrams, and bulleted lists. Students can read the text from cover to cover to gain a general foundation of knowledge that can be built upon when they begin their rotation, then use specific chapters to review a sub-specialty before starting a new rotation or seeing a patient with a sub-specialty attending. Topics covered include lung cancer, pulmonary resection, pleural empyema, thoracic outlet syndrome, esophageal disorders, tracheal malignancies, and much more.Practical and user-friendly, Thoracic Surgery Clerkship is the ideal, on-the-spot resource for medical students and practitioners seeking fast facts on diagnosis and management. Its bullet-pointed outline format makes it a perfect quick reference, and its content breadth covers the most commonly encountered problems in clinical practice.

Thoracic Surgery for the Acute Care Surgeon (Hot Topics in Acute Care Surgery and Trauma)

by Joseph M. Galante Raul Coimbra

This volume is a “how-to guide” to treating thoracic trauma and emergencies for acute care surgeons. It highlights the diagnosis and management of thoracic disease and injuries, and each chapter includes algorithms that lead readers through the process of identifying and treating many common and some uncommon thoracic pathologies. The international team of authors provides readers with a unique and diverse approach to the operative and non-operative challenges encountered by ACS surgeons. The large number of figures offers readers insights into what they can expect to see when caring for these patients. The editors understand that the management of adults and children differ and have included a specific chapter on pediatrics. Given the broad audience and diverse settings in which the text can be used, the authors also provide details of care in limited-resource environments. The volume is a valuable tool for professionals interested in thoracic surgery and acute care surgery.

Thoracic Surgical Techniques

by Francis C. Wells Aman S. Coonar

This heavily revised second edition of this book provides a comprehensive overview of both common and rarely performed thoracic surgical techniques. Techniques covered include thymectomy, left and right lower lobectomy, rib resection for empyema, median sternotomy and lung biopsies. Emphasis is focused on the practical steps necessary to successfully and reliably perform the techniques covered, while acknowledgement is also given to individual variations in how these techniques are performed. Thoracic Surgical Techniques provides a detailed clinical illustrative guide for successfully performing a range of procedures reliably. Its large number of detailed illustrations and concise technical descriptions provides an invaluable resource for all practising and trainee thoracic surgeons.

Thoracic Ultrasound and Integrated Imaging

by Andrea Aliverti Francesco Feletti Bruna Malta

This book focuses on thoracic ultrasound, a versatile, diagnostically accurate, low-cost, noninvasive and non-ionizing imaging technique. Thanks to portable devices, the method can be used to provide quick and accurate diagnoses in emergency settings, during transport, or at the patient’s bedside in intensive care units. In addition, as a dynamic examination that allows “real-time” assessment, it can be used to optimize diagnoses, the use of respiratory support equipment, surgical interventions and physiopathological assessments, both in critical patients and those with chronic conditions. Lastly, since it avoids ionizing radiation, thoracic ultrasound offers a first-line diagnostic tool for thoracic disease assessment in connection with pregnancy, neonatology and pediatrics. Pursuing a practical approach, this book also addresses the technological components that are needed in order to adequately set up the equipment. This integrated approach provides non-radiologists with essential know-how on using thoracic ultrasound as an extension of their physical examinations. Specific chapters are dedicated to thoracic ultrasound applications in neonatology, pediatrics and emergency medicine, as well as guided procedures and diaphragm function studies. Thoracic ultrasound has been a central element in the editors’ clinical and experimental work for several years, and the book also includes contributions by prominent international experts on specific applications. Given its content and scope, the book will be of interest to all medical practitioners seeking a practical approach to thoracic ultrasound.

Thoracoscopic Repair of Esophageal Atresia

by Ravi P Kanojia

Esophageal atresia is a common neonatal emergency, and surgical repair in the newborn period is conventionally achieved by thoracotomy. With the development in pediatric minimal access surgery, esophageal atresia repair has been done with thoracoscopy after its first description in 1999. Many centers now prefer the thoracoscopic approach, which is claimed to be beneficial in terms of outcome both in the short and long term. Neonatal thoracoscopy is a difficult procedure and has a long learning curve. It requires a team approach with a competent anesthetist and surgical assistant. A surgeon alone cannot accomplish this procedure. This book presents comprehensive details on the procedure of thoracoscopic repair of esophageal atresia. The chapters sequentially explain all the procedure steps, from setup, instrumentation, patient selection, and ergonomics to detailed stepwise descriptions of the operative procedure. Since esophageal atresia can have so many variations in anatomy, the chapters cover how to tackle these variations. To keep the reader's interest, a detailed review of history and current literature, along with controversies, is presented. Interested readers will start from the history as the first chapter and can go through the descriptions of the entire procedure from start to finish. Any Pediatric surgery trainee interested in Pediatric Minimal access discipline will find this book as a one-stop resource on everything he wants to know about Thoracoscopic repair of esophageal atresia. The book also includes coverage of non-surgical aspects such as anesthesia and ventilation and effects on cerebral oxygenation during thoracoscopy. The book provides easy-to-understand English and is richly supplemented with illustrations and high-resolution operative photographs. Video clips also supplement the text wherever an operative step is explained. These videos are linked to the publisher’s website for easy access.

Thoracoscopy for Pulmonologists: A Didactic Approach

by Gianfranco Tassi Jean-Marie Tschopp Philippe Astoul

There is an increasing need for medical thoracoscopy performed by pulmonologists, which may be video assisted and has the advantage of being very cost-effective. This book is a comprehensive and up-to-date guide to thoracoscopy for pulmonologists that documents the considerable progress in endoscopic telescopes and instrumentation. Clear practical guidance is provided on technique, and diagnostic, therapeutic, and interventional applications of thoracoscopy are all carefully examined with the aid of high-quality illustrations. Although medical thoracoscopy is much less invasive than thoracotomy, complications can occur in a small number of cases; these are discussed and advice on prevention is provided. The concluding section examines the future of the field, covering developments such as 'mini' thoracoscopy, autofluorescence thoracoscopy, and flexi-rigid thoracoscopy.

The Thorax: Medical, Radiological, and Pathological Assessment

by Cesar A. Moran Mylene T. Truong Patricia M. de Groot

The current medical practice has become more of a team effort rather than an isolated practice. The current evaluation of patients in the daily practice is essentially performed by medical assessment of the patient in question followed by diagnostic imaging, and when needed and possible the evaluation of tissue for diagnosis with its subsequent assessment of biomarkers and other ancillary tools that play an important role in the evaluation and prognosis. The book herein proposed will exactly provide such assessment focused in the thoracic assessment of patients afflicted with any particular disease of the thorax. Expert clinician in pulmonary medicine will provide the state of the art in the evaluation of such patients, which will provide the most important background in the clinical impression and further assessment of these patients. This assessment in most cases is followed by the evaluation of imaging, which provides a highly important information of not only the exact location of the process but also of the nature of whether is localized, infiltrative, diffuse, bilateral, etc., as well as the possible compromise of other adjacent structures. Such information is crucial as imaging and clinical information will provide a working diagnosis, which ultimately will be defined by the pathological assessment. Therefore, in real practice neither one of these subspecialties works alone or in isolation. On the contrary, each one depends on the other for the final diagnosis and proper management of patients with thoracic diseases. Based on such experience is that the current text will provide in the same text of the needed information that a clinician, radiologist or pathologist will need in order to arrive to the best possible conclusion. The scope of this book is unique in its nature as currently, even though there are several text on either one of those specialties, those publication are strictly on the either radiology, medicine or pathology. Our proposed text will bring all those together in a single text and written by experts in their respective field. This book should be of interest to all of those in the practice of thoracic medicine (radiologist, pulmonologist, pathologists) and any one who in the general practice is confronted with the evaluation of these patients.

The Thorax: An integrated approach

by Catherine Ryan Diane Lee Nancy Keeney Smith

This clinical textbook will update the reader on the relevant anatomy, known biomechanics, clinical assessment, musculoskeletal conditions and treatment of the thorax and how these relate to the function of the whole body. An integrated biopsychosocial model (the Integrated Systems Model - ISM) will be highlighted in this text and used as a foundation for clinicians to organize their knowledge from multiple sources. The text emphasizes the current suggestion from the evidence that treatment be individualized and that clinical reasoning form the basis for treatment decisions.Richly illustrated with 3D-rendered colour anatomical drawings, and over 250 clinical photographs, The Thorax: An integrated approach is the definitive manual on the thorax for all bodyworkers helping patients improve mobility and control of the trunk.

The Thorax (Cancer Dissemination Pathways)

by Nicola Sverzellati Mario Silva

This book highlights the differences, in terms of neoplastic dissemination pathways, between various types of thoracic cancers. It presents and discusses a comprehensive schematic overview of tumors of the lung parenchyma, of the mediastinum, of the pleura, and of the chest wall. For each tumor, it details the local spread and the lymphatic and vascular dissemination, and it describes the challenging staging of lung tumors with mutations. Illustrations and artwork enrich the content and help readers to understand and visualize tumor spread. The book is of great interest to professionals involved in the study, diagnosis and treatment of thoracic pathologies, as well as to residents in radiology, oncology and pulmonology.

The Thorax -- Part A: Physiology (In Three Parts), Second Edition (Lung Biology in Health and Disease)

by Charis Roussos

This book provides a comprehensive, authoritative, and contemporary discussion of the physiology and pathophysiology of the chest wall as well as an overview of the diagnostic and therapeutic modalities. It is an invaluable aid to clinical investigators.

The Thorax, ---Part B: Applied Physiology (In Three Parts)

by Charis Roussos Theodoros Vassilakopoulos

This timely Second Edition of a landmark reference furnishes in-depth examinations of the latest developments in the physiology, pathophysiology, and clinical relevance of the respiratory muscles and chest wall-reflecting the explosion of information that has occurred since the publication of the previous edition.

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