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The Ubiquitin System in Health and Disease
by Bernhard Haendler Stefan JentschThe ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. A deregulation of this system has been reported in various pathologies including cancer, neurodegenerative diseases and immune disorders. Most of the enzymes involved in adding or removing ubiquitin chains have been identified, but often their direct substrate and the type of ubiquitylation remains to be clarified. A better understanding of the mechanisms governing these processes is likely to allow the identification of novel targets for pharmacological intervention and pave the way for improved therapies. The latest developments in this rapidly moving field are presented in this book.
The Ulnar Nerve
by Giuliano Gentili Mario Di NapoliThis book systematically reviews sensory and motor nerve conduction studies on the ulnar nerve, from pilot human studies of peripheral nerve conduction in the 1950s through to the most recent scientific evidence. Precise descriptions are provided of approx. 70 nerve conduction techniques that were reproduced in the laboratory, with organization of the techniques according to practical criteria for ease of reference. Particular attention is devoted to those techniques that have shown higher sensitivity and specificity in diagnosis of compressive mononeuropathies, such as ulnar neuropathy at the elbow or wrist. Normal and pathological values derived from the original articles and the subsequent literature are presented, and the wealth of illustrative material facilitates comprehension and reproduction of each technique. The volume is completed by a detailed, well-illustrated glossary explaining the more commonly used terms in electrodiagnostic medicine. This book will appeal to novice and experienced neurologists, students, clinical neurophysiology technicians, and rehabilitation physicians. It represents a logical extension of the volumes on the median nerve recently published by Springer.
The Ultimate Enhancement of Morality (SpringerBriefs in Ethics)
by Vojin RakićThis book deals with good, evil, happiness and morally enhanced post-humans. It offers a succinct historical elaboration of philosophical stances towards morality and happiness, focusing on Kant's ideas in particular. Human augmented ethical maturity in a futuristic version of Kant’s Ethical Commonwealth implies, among else, voluntary moral bio-enhancement (VMBE); consequently, more happiness – as morality and happiness are in a circularly supportive relationship; ultimate morality (UM). UM is in its own way a universal morality. In line with the contention that Kant’s vision of the (not immediate but more distant) future of humanity is one of a cosmopolitan moral order in which humans act virtuously in the broadest possible community, that is, humanity, it is justified to conclude that successful VMBE is conducive to Kant’s vision. In this context the book is of great interest to a broad audience, such as those interested in VMBE and novel conceptions of morality, and those with an interest in the historical development of morality and happiness, in philosophy (specifically, ethics) and in post-humanity.
The Ultimate Guide for Laser and IPL in the Aesthetic Field
by Kamal Alhallak Adel Abdulhafid Salem Tomi Dima OmranThis book offers practitioners a comprehensive reference to light-based treatments that combines theory and best practices. It is unique in that it compares the various modalities and platforms of laser and IPL treatments while also discussing the most recent technological advancements. It also includes comprehensive treatment protocols, settings, and laser operating procedures. Furthermore, the book compares the mechanism of action of different lasers based on the skin-light interaction according to wavelength, pulse width, and delivery methods, making it invaluable to new practitioners and medical directors in the aesthetic medicine field.The book includes over 100 colour images and videos to help readers better understand techniques and treatment procedures. This visual aid makes the book especially useful when following treatment protocols. Chapters delve into every aspect of laser and IPL in aesthetics, including skin anatomy, hair reduction, vascular lesions, pigmentary conditions, scar remodelling, stretch mark revision, facial rejuvenation, skin toning technologies and wrinkle reduction methods. Furthermore, the book includes two chapters that will help practitioners invest in new and refurbished laser machines. The Ultimate Guide for Laser and IPL in the Aesthetic Field, with its comprehensive coverage of laser and IPL treatments in aesthetics, is an indispensable resource for healthcare professionals looking to refine their skills or refresh their knowledge on light-based treatments. It combines theories with practical aspects to provide the reader with everything they need to know about effective treatment delivery, making it an invaluable reference for any aesthetic practitioner!
The Ultimate Guide to Passing Clinical Medicine Finals (MasterPass)
by Dominic Greenyer Mohammed Faysal Malik Asiya MaulaA well prepared student takes the initiative to create learning opportunities and propel themselves towards qualification; we find that the better prepared you are, the luckier you become. From the Preface The key to passing clinical finals is not a secret; adequate preparation and the ability to think logically and speak clearly are all hallmarks of a successful candidate. This unique guide gives final year students the knowledge and confidence required to pass their examinations with insiders' tips on particular information and skills required to be a top candidate. It is ideal as both a revision aid in the weeks leading up to the examination, and as an aide-memoire the night before.
The Ultimate Guide to Passing Surgical Clinical Finals (MasterPass)
by Mohammed Faysal Malik Asiya MaulaMedical students lack information on preparing for clinical surgical finals, particularly on common mistakes and the features which identify successful candidates. The Ultimate Guide to Passing Surgical Clinical Finals is an accessible and comprehensive preparation aid, equipping final year medical students with the knowledge and skills that they are expected to demonstrate both in clinical surgical finals and in clinical practice as junior doctors. Its tutorial-style approach provides advice on how to think logically, speak coherently, and demonstrate both breadth and depth of knowledge - all key hallmarks of successful candidates. The book's broad approach reflects the full range of skills and knowledge covered by modern curricula, including instruments, procedures and the increasing use of surgical imaging. It is vital reading for clinical year medical students preparing for final examinations in surgery, and for postgraduate students who wish to improve their presentation, viva and OSCE clinical examination skills. 'This book's approach is in the best surgical traditions of ordered thinking when it comes to the examination itself. I admire this book and commend it to you.' - From the Foreword by David E Khoo
The Ultimate Guide to Point-of-Care Ultrasound-Guided Procedures
by Michael Blaivas Srikar AdhikariThis comprehensive book provides an in-depth examination of a broad range of procedures that benefit from ultrasound guidance in the point-of-care setting. It covers common procedures such as ultrasound-guided central and peripheral venous access to regional nerve blocks, temporary pacemaker placement, joint aspirations, percutaneous drainage, a variety of injections and airway management. Chapters examine a variety of topics critical to successful ultrasound procedures, including relevant sonoantomy, necessary equipment, proper preparation, potential complications, existing evidence and how to integrate these procedures into clinical practice. For each procedure, the book includes step-by-step instructions and discusses the advantages of ultrasound guidance over traditional techniques. Providing rich procedural detail to help in clinical decision making, The Ultimate Guide to Point-of-Care Ultrasound-Guided Procedures is an indispensable, go-to reference for all health care providers who work in a variety of clinical settings including primary care, emergency department, urgent care, intensive care units, pediatrics, pre-hospital settings and those who practice in the growing number of new ultrasound programs in these specialties.
The Ultimate Guide to Yin Yang
by Antony CumminsThe first book to fully explore and explain the concept of yin yang, breaking it down in easy-to-follow terms for all those interested in Daoism, alternative medicine, martial arts and other Eastern fields of study. Illustrated with striking red/black graphics that make the concepts more accessible.The concept of yin yang can be found in some of the oldest writing in the world. It is fundamental to Chinese thought and the route to understanding most Chinese practices, from Traditional Chinese Medicine to Daoism and feng shui. It also offers us ways of enhancing our own lives, establishing greater balance not only in our own environment but also in the wider world if we can work with other people to follow nature's flow. The central question of the book is "What is yin yang?" Step by step, with plenty of helpful illustrations and graphics, it explores the history and changing uses of yin yang - not forgetting the pronunciation and spelling (why yinyang is actually better than yin yang). The book also makes suggestions for working with yin yang, from observing the landscape to get a sense of the ebb and flow of energy through the world, to studying the patterns of nature in order to take what you need but not too much, to approaching sex as a cosmic ritual. After reading this book, readers will understand how to position themselves so that yin yang fills their lives with abundance - how to be in the right place at the right time.
The Ultimate Medical School Rotation Guide
by Stewart H. Lecker Bliss J. ChangWritten by the top medical student rotators, this book provides medical students with the often elusive information and skills required to ace their clinical rotationsChapters cover all major medical sub-specialties such as internal medicine, general surgery, cardiology, dermatology, orthopedics, neurosurgery, and ophthalmology. Additionally, the book offers many novel features including a review of core rotation skills for oral presentations and a walk-through of a day in the life of the medical student on a particular rotation. It focuses on the common cases that students actually encounter in the hospital. This format thereby administers a complete, concise overview of what is needed for each rotationA unique resource, The Ultimate Medical School Rotation Guide is not only instructional and comprehensive, but also assuring and supportive as it encourages students to appreciate this rewarding time in their medical careers
The Ultimate Obamacare Handbook (2015-2016 edition): A Definitive Guide to the Benefits, Rights, Responsibilities, and Potential Pitfalls of the Affordable Care Act
by Kimberly AmadeoObamacare can save you money, but only if you know how it really works. Americans have been barraged with fifteen times more negative than positive news about Obamacare. As a result, 40 percent of the people who dislike it actually qualified for insurance subsidies and don't realize it. Hardworking, middle-class families need facts, not opinions, to get all the benefits they deserve. Here you'll find: A guide to buying low-cost health insurance Step-by-step instructions to signing up for insurance Directions to apply for Obamacare exemptions Eligibility requirements for subsidies Definitions of insurance, health care, and Obama terms Real-life stories of people who have already been helped This handbook refutes the myths about the Affordable Care Act with research-based evidence. It reveals the seven reasons why health care costs so much, as well as how the ACA attacks those costs. You'll learn who really gets benefits from subsidies and who pays for them. Most importantly, this book uncovers how the ACA might save you and your family money in 2016 and beyond.
The Ultimate Pet Health Guide: Breakthrough Nutrition and Integrative Care for Dogs and Cats
by Gary RichterAs a holistic veterinarian and scientist, Dr. Gary Richter helps dog and cat owners to navigate the thicket of treatment options and separate the fact from the fiction. He wants us to use what actually works, not just what Western science or alternative medicine say "should" work.This multifaceted approach to health is known as integrative medicine. Dr. Richter examines traditional medicine from many cultures alongside modern medical techniques, describing the best of complementary care and the best of conventional veterinary medicine. Every treatment he recommends has the backing of scientific research or years of successful outcomes in his clinical practice. After explaining the treatment, he offers specific recommendations for an integrative approach to common diseases, including allergies, skin conditions, diabetes, heart disease, and cancer.A holistic approach to health includes nutrition, as it sets up the foundation for your pet&’s health. Dr. Richter cuts through the hype in the pet-food world and explains how to choose the best commercial foods and supplements, and even includes both raw and cooked dog- and cat-food recipes for general diet as well as to treat specific needs. He also explains how we can use the right foods and supplements to "hack" the body&’s processes, including the immune system.
The Ultimate Retirement Guide for 50+: Winning Strategies to Make Your Money Last a Lifetime (Revised & Updated for 2025)
by Suze OrmanThe instant NEW YORK TIMES BESTSELLERWALL STREET JOURNAL BESTSELLERPUBLISHERS WEEKLY BESTSELLERUSA TODAY BESTSELLER#1 PERSONAL FINANCE EXPERTRevised & Updated for 2025THE PATH TO YOUR ULTIMATE RETIREMENT STARTS RIGHT HERE!Retirement today is more complex than ever before. It is most definitely not your parents' retirement. You will have to make decisions that weren't even part of the picture a generation ago. Without a clear-cut path to manage the money you&’ve saved, you may feel like you're all on your own.Except you're not—because Suze Orman has your back.Suze is America's most recognized personal finance expert for a reason. She's been dispensing actionable advice for years to people seeking financial security. Now, in this revised and updated Ultimate Retirement Guide for 50+, which reflects recent changes in retirement rules passed by Congress, Suze gives you the no-nonsense advice and practical tools you need to plan wisely for your retirement in today's ever-changing landscape.You'll find new rules for downsizing, spending wisely, delaying Social Security benefits, and more—starting where you are right now.Suze knows money decisions are never just about money. She understands your hopes, your fears, your wishes, and your desires for your own life as well as for your loved ones. She will guide you on how to let go of regret and fear, and with her unparalleled knowledge and unique empathy, she will reveal practical and personal steps so you can always live your Ultimate Retirement life."I wrote this book for you," Suze says. "The worried, the fearful, the anxious. I know you need help navigating the road ahead. I've helped steer people toward happy and secure retirements my whole life, and that's exactly what I want to do for you."
The Ultimate Self-Sufficiency Manual: 200+ Tips for Living Off the Grid
by Tim MacWelchLooking for a greater sense of control in the chaotic world of today? Concerned about your dependence on existing food and power sources, and other systems beyond your control? Empower yourself with the gift of self reliance–with the Total Self Sufficiency Manual, which has over 220 tips and techniques to empower your independence from survival expert and New York Times-bestselling author Tim MacWelch.
The Ultimate Student’s Guide to Scientific Research
by Samuel J. Rubin Nir QvitA scientific career is a long and winding journey. Many factors assemble to determine the trajectory and products of scientific inquiry. This book addresses the scientific career path comprehensively, ranging from how to build a strong foundational knowledge and skill base, to training programs, composing winning research proposals and grants, conducting excellent research, writing papers and reports, collaborative research programs, bridging academia and industry, career advancement, and more. Guides where, how, and what to study in undergraduate, post-baccalaureate, graduate, and post-graduate training programs and addresses important crossroads throughout the continuum of training and beyond. Highlights best practices, techniques, and nuances for creating a successful scientific career. Provides critical insights for traversing major milestones and decision-points in a scientific career and serves as a resources for reference throughout stages of advancement. Discusses alternative career opportunities for individuals trained in sciences. Offers students, researchers, and other scientists across all stages of their careers with accessible, engaging, and useful insider tips.
The Ultimate Survival Medicine Guide: Emergency Preparedness for Any Disaster
by Joseph Alton Amy Alton<P> The Ultimate Survival Medicine Guide: Emergency Preparedness for any Disaster is the new abridged version of the bestselling book The Survival Medicine Handbook. This unique medical book is meant to enable the average person to handle injuries and illness in situations in which modern medical facilities and professionals aren’t available due to a disaster. <P> This book is written by America’s top medical preparedness experts: Joe Alton, MD, and Amy Alton, ARNP. Their mission: to put a medically prepared person in every family for when medical help is not on the way. Using decades of medical experience, they address, in plain language, dozens of medical issues associated with surviving disasters and epidemics. The Altons also discuss the medical supplies needed to become a medical asset to your family and community as well as alternative and natural strategies for when pharmaceuticals aren’t available. <P> Most medical books will send you to the doctor or hospital when an emergency happens. The Ultimate Survival Medicine Guide assumes what might actually happen--that the average person could be left without medical help in a disaster. With this unique book, you’ll have a head start on keeping your family healthy in times of trouble.
The Ultimate Vaccine Timeline: A Fact-Packed History of Vaccines and Their Makers
by Shaz KhanDive deep into a comprehensive fact-packed history of vaccines that includes information on vaccine manufacturers and their evolution over time. Browse through an extensive series of verifiable and documented facts on vaccines. For well over a century, vaccines have been routinely recommended to billions of people worldwide, mostly children and babies. With an ever-increasing portfolio of vaccines using novel technologies on the global market, it is important now more than ever to consolidate a chronology of facts relating to human vaccination. Considering the current climate of censorship around vaccines, this publication will contribute to an expanded understanding of this important medical intervention. Spanning over fifteen hundred years, this thoroughly researched timeline is an educational tool for any researcher, student, doctor, scientist, parent, or curious human being wishing to gain a broader perspective and insight into the complex and vast landscape of human vaccination. From smallpox to shingles; tetanus to tuberculosis; hepatitis B to HPV, discover when, where, and by whom these vaccines were invented and marketed. Including a historical timeline of pharmaceutical company beginnings, mergers and acquisitions since the seventeenth century, this illustrated reference book shines a light on the controversial subject of vaccines and their makers.
The Ultimate Weight Solution for Teens: The 7 Keys to Weight Freedom
by Jay McgrawWhat his dad did for adults with "The Ultimate Weight Solution," Jay McGraw, son of Dr. Phil McGraw, now tailors for teens. This is a book to promote weight wellness for young people by the author of "Life Strategies for Teens."
The Ultimate pH Solution: Balance Your Body Chemistry to Prevent Disease and Lose Weight
by Michelle Schoffro CookControl the level of acid in your body and reclaim your health with this simple, step-by-step programBeginning a healthier lifestyle can be as easy as starting your day sipping a glass of water with a squeeze of lemon juice. Drinking this simple drink is only one of the many ways, all outlined in The Ultimate pH Solution, that you can change your body's pH and ward off disease. Too much acid in your blood can cause a host of health problems, but with cutting-edge, medically sound research, this indispensable guide offers an easy-to-follow plan and simple lifestyle changes that will help you kick acid and stay healthy.The Ultimate pH Solution also includes real-life success stories of people who have overcome disease and lost weight by balancing their pH levels, along with 50 recipes for delicious pH-powerful dishes. Learn why high-protein diets may be harmful to your health, why eating dairy may not help you avoid osteoporosis, and how to lower the acid levels in your body for optimal health.
The Umbilical Cord Blood Controversies in Medical Law (Biomedical Law and Ethics Library)
by Karen DevineSince the therapeutic value of umbilical cord blood (UCB) stem cells was first recognised in the late 1980s, there has been a proliferation of both public and private UCB banks worldwide. However, the ability to utilise such a potentially valuable resource has provoked a number of controversies. In a distinctly accessible style, this book unpacks the socio-legal implications of the UCB collection process and constructs a detailed analysis of the law and ethics that surrounds UCB banking in the UK, including ownership of the cells. Its enquiry is located within the theoretical framework of altruism versus self-interest and explores the notions of risk and choice associated with this distinctive blend of public/private healthcare provision. The book evaluates the impact of the Human Tissue Act 2004 and the European Union Tissues and Cells Directive (2004/23/EC) on the UCB industry and provides a unique insight into the effect that the law may have on the NHS whose maternity staff and premises are used to collect UCB. This book would be of interest primarily to a UK readership in addition to expectant families, health professionals, students, academics, practitioners and the UCB industry elsewhere in the world.
The Unapologetic Guide To Black Mental Health: Navigate An Unequal System, Learn Tools For Emotional Wellness, And Get The Help You Deserve
by Rheeda WalkerWe can’t deny it any longer: there is a Black mental health crisis in our world today. Black people die at disproportionately high rates due to chronic illness, suffer from poverty, under-education, and the effects of racism. This book is an exploration of Black mental health in today’s world, the forces that have undermined mental health progress for African Americans, and what needs to happen for African Americans to heal psychological distress, find community, and undo years of stigma and marginalization in order to access effective mental health care. <p><p> In The Unapologetic Guide to Black Mental Health, psychologist and African American mental health expert Rheeda Walker offers important information on the mental health crisis in the Black community, how to combat stigma, spot potential mental illness, how to practice emotional wellness, and how to get the best care possible in system steeped in racial bias. <p> It’s past time to take Black mental health seriously. Whether you suffer yourself, have a loved one who needs help, or are a mental health professional working with the Black community, this book is an essential and much-needed resource.
The Uncanny Rise of Medical Hypnotism, 1888–1914: Between Imagination and Suggestion (Mental Health in Historical Perspective)
by Gordon David BatesThis book explores the improbable rise of medical hypnotism in Victorian Britain and its subsequent assimilation and neglect. It follows the careers of the ‘New Hypnotists’: Charles Lloyd Tuckey, John Milne Bramwell, George Kingsbury and Robert Felkin. This loosely knit group all trained with the Suggestion School of Nancy and published books on hypnotism. They had to confront the many public and medical prejudices against the trance state which had persisted after the scandalous disgrace of John Elliotson and medical mesmerism, fifty years before. Hypnotism was a highly contested technology and in the 1890s the debates about safety and utility were fought in the national newspapers as well as the medical journals. The new hypnotists took on the might of the medical institutions personified by Ernest Hart, Editor of the British Medical Journal. However their timing was propitious, as the rise of faith-healing forced the medical profession to confront the non-physical therapeutic aspects of the doctor-patient relationship. The hypnotic discourse was shaped by these developments, but also by the fascination of the general public, novelists, occultists, psychic investigators, educationalists and spiritualists in the myriad possibilities of the trance state. Despite growing interest in the prehistory of British psychology and talking therapies, and the recent challenges to the primacy of Freudian histories, there are few accounts of the development of British ‘eclectic therapy’. This book uses the New Hypnotists as a lens to examine Victorian medicine and society, exploring their role in establishing the term ‘psychotherapy,’ and legitimising medical hypnotism, a precursor of psychological therapies.
The Uncertain Art: Thoughts on a Life in Medicine
by Sherwin B. Nuland"Life is short, and the Art so long; the occasion fleeting; experience fallacious; and judgment difficult. The physician must not only be prepared to do what is right himself, but also to make the patient, the attendants, and the externals, cooperate."-attributed to Hippocrates, c. 400 B.C.E. The award-winning author of How We Die and The Art of Aging, venerated physician Sherwin B. Nuland has now written his most thoughtful and engaging book. The Uncertain Art is a superb collection of essays about the vital mix of expertise, intuition, sound judgment, and pure chance that plays a part in a doctor's practice and life. Drawing from history, the recent past, and his own life, Nuland weaves a tapestry of compelling stories in which doctors have had to make decisions in the face of uncertainty. Topics include the primitive (and sometimes illegal) procedures doctors once practiced with good intentions, such as grave robbing and prescribing cocaine as an anesthetic (which resulted in a physician becoming America's first cocaine addict); the curious "cures" for irregularity touted by people from the ancient Egyptians to the cereal titan John Harvey Kellogg and bodybuilder Charles Atlas; and healers grappling with today's complex moral and ethical quandaries, from cloning to gene therapy to the adoption of Eastern practices like acupuncture. Nuland also recounts his most dramatic experiences in a forty-year medical career: the time he was called out of the audience of a Broadway play to help a man having a heart attack (when no other doctor there would respond), and how he formed a profound friendship with an unforgettable-and doomed-heart patient. Behind these inspiring accounts always lie the mysteries of the human body and human nature, the manner in which the ill can will themselves back to health and the odd and essential interactions between a body's own healing mechanisms and a doctor's prescriptions.Riveting and wise, amusing and heartrending, The Uncertain Art is Sherwin Nuland's best work, gems from a man who has spent his professional life acting in the face of ambiguity and sharing what he has learned.
The Uncomplicated Guide to Diabetes Complications
by Marvin E. Levin Michael A. PfeiferDiabetes complications can be prevented, and they can be treated.First you need to know how serious and life threatening the issues are that you're up against. Learn how to take care of yourself to prevent diabetes complications before they become deadly. Uncomplicated Guide to Diabetes Complications is divided into chapters on major parts and systems of the body and the diabetic complications that may affect them.This new edition covers everything from heart disease prevention, eye problems, and diabetic kidney diseases to gastroparesis, GI problems, and critical diabetic foot care. Also included is the latest information on new diabetes medications, overcoming depression, and even erectile dysfunction.Get the edge you need to protect yourself and to prevent or slow down diabetes complications. Most people affected by diabetes will experience complications as a result of diabetes symptoms. How to treat and prevent those complications seems overwhelming, but The Uncomplicated Guide to Diabetes Complications makes understanding what to do a snap.
The Unconscious: Theory, Research, and Clinical Implications (Psychoanalysis and Psychological Science)
by Joel Weinberger Valentina StoychevaWeaving together state-of-the-art research, theory, and clinical insights, this book provides a new understanding of the unconscious and its centrality in human functioning. The authors review heuristics, implicit memory, implicit learning, attribution theory, implicit motivation, automaticity, affective versus cognitive salience, embodied cognition, and clinical theories of unconscious functioning. They integrate this work with cognitive neuroscience views of the mind to create an empirically supported model of the unconscious. Arguing that widely used psychotherapies--including both psychodynamic and cognitive approaches--have not kept pace with current science, the book identifies promising directions for clinical practice.
The Underactive Bladder
by Michael B. Chancellor Ananias C. DioknoThis book provides up-to-date guidance on optimal care of the patient with an underactive bladder. It covers all aspects of management, including clinical evaluation, urodynamic diagnosis, standard care, drug therapy, and emerging treatment options. Nursing issues are extensively discussed, and advice offered on the use of catheters and avoidance of catheter-related complications. Further chapters address epidemiology, pathophysiology, animal modeling, and health care costs. While most practitioners are familiar with overactive bladder, the converse condition of underactive bladder has generally remained far below the radar. As a consequence, there is still a lack of empirically validated treatments and effective treatment strategies. This is a matter of concern, especially as the burden of the condition is expected to rise in line with the aging of global populations. The Underactive Bladder is a major step forward in raising awareness, exploring best practices in patient care, and searching for future therapies. It will be invaluable for urologists, geriatricians, other specialists, researchers, and nurses.