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Tobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment
by Ming D. LiThis book provides the most recent knowledge on almost all key aspects of the health impact of tobacco smoking. Its 21 chapters focus on both preclinical and clinical studies. The contents are broad, covering the epidemiology of tobacco smoking; genetic epidemiology; identification of susceptibility genomic regions, genes, and pathways as determined by both human and animal studies; evolutionary relations among the different nAChR subunit genes that are so important to the nicotine response; smoking-related diseases; E-cigarettes; and smoking cessation. Furthermore, each chapter includes a detailed and comprehensive list of key references. For both clinical and basic researchers, this book is a valuable resource on nicotine dependence and other addictions.
Tobacco War: Inside the California Battles
by Stanton A. Glantz Edith D. BalbachTobacco War charts the dramatic and complex history of tobacco politics in California over the past quarter century. Beginning with the activities of a small band of activists who, in the 1970s, put forward the radical notion that people should not have to breathe second-hand tobacco smoke, Stanton Glantz and Edith Balbach follow the movement through the 1980s, when activists created hundreds of city and county ordinances by working through their local officials, to the present--when tobacco is a highly visible issue in American politics and smoke-free restaurants and bars are a reality throughout the state. The authors show how these accomplishments rest on the groundwork laid over the past two decades by tobacco control activists who have worked across the U.S. to change how people view the tobacco industry and its behavior. <P> Tobacco War is accessibly written, balanced, and meticulously researched. The California experience provides a graphic demonstration of the successes and failures of both the tobacco industry and public health forces. It shows how public health advocates slowly learned to control the terms of the debate and how they discovered that simply establishing tobacco control programs was not enough, that constant vigilance was necessary to protect programs from a hostile legislature and governor. In the end, the California experience proves that it is possible to dramatically change how people think about tobacco and the tobacco industry and to rapidly reduce tobacco consumption. But California's experience also demonstrates that it is possible to run such programs successfully only as long as the public health community exerts power effectively. With legal settlements bringing big dollars to tobacco control programs in every state, this book is must reading for anyone interested in battling and beating the tobacco industry.
Tobacco or Health?
by Knut-Olaf Haustein David GronebergThis book presents a summary of the consequences that tobacco smoking has on health, taking into account all organ systems affected, such as the respiratory tract, cardiovascular system, central nervous system, and urinary tract, including mineral metabolism, the pregnant woman, etc. It also describes primary prevention measures as well as possible intervention modalities, established on evidence-based medicine, to help individuals stop smoking. The book is of a high scientific standard and thus differs from many popular-science treatises. It helps inform the reader of all smoking-related problems.
Tobacco-Specific N-Nitrosamines Recent Advances
by Roger O. McClellanThis remarkable book provides updates on various aspects of tobacco - its chemical and biological nature, and its physiological effects.
Tocotrienols: Vitamin E Beyond Tocopherols, Second Edition
by Victor R. Preedy Ronald Ross Watson Barrie TanThe first 90 years of vitamin E research has produced prolific and notable discoveries, but until the last few decades, attention has been given mostly to the biological activities and underlying mechanisms of alpha-tocopherol, which we now know is one of more than eight vitamin E isomers. Currently, the non-tocopherol vitamin E molecule tocotrieno
Toda la verdad sobre el COVID-19: La historia detrás del gran reinicio, los pasaportes de vacunación y la nueva normalidad
by Joseph Mercola Ronnie CumminsUSA Today, Wall Street Journal, Bestseller Internacional“Una [crítica] elocuente, carismática e informada de un sistema corrupto.”—Robert F. Kennedy, Jr.,del prólogo“El Dr. Mercola es un visionario, pionero y líder.”—Del Bigtree, anfitrión de The HighwireEl muchas veces ganador de libros más vendidos del New York Times, Dr. Mercola y Ronnie Cummins, fundador y director de la Asociación de Consumidores Orgánicos y Vía Orgánica, se unen para exponer la verdad - y terminar con la locura - sobre el COVID-19. Mediante una robusta investigación, más de 500 referencias de artículos de revistas científicas arbitradas, estadísticas oficiales gubernamentales y descubrimientos de investigación de salud pública de todo el mundo, los autores muestran la necesidad urgente de un despertar global. Es hora de unirnos, exigir la verdad y tomar el control de nuestra salud. La Verdad Sobre el COVID-19 es tu invitación a unirte al Dr. Mercola y Cummins mientras educan y organizan un futuro sano, equitativo, democrático y regenerativo. *Edición actualizada con un nuevo prólogo*
Today's Curiosity is Tomorrow's Cure: The Case for Basic Biomedical Research
by Steve CaplanBasic curiosity-driven biomedical science has delivered many of today’s most significant medical advances. This book provides clearly explained examples from recent biomedical history and includes convincing arguments for sustaining a robust portfolio of basic research. Intended as an engaging read, which will delight undergraduate and graduate students, as well as scientific researchers, it is full-throated advocacy of basic science. Illustrations and examples include the discoveries of penicillin and insulin, and the breakthrough elucidation of the genetic code. Providing both compelling rationale in support of basic science, and a fascinating look through the history of modern biomedical research, this book highlights with stirring examples why basic biomedical research is so important, and how so many key advances in medicine are derived from basic research. The book also offers a rationale for scientific inquiry and a broader understanding of the history of modern biomedical research missing from today’s classrooms. Key Features 1) Provides clear explanations of great scientific discoveries 2) Illustrates connections between basic research findings and modern medicine 3) Includes compelling graphics/diagrams/illustrations 4) Accessible to the general public 5) Offers background for more specialized readers, including researchers as well as those with advanced degrees. Related Titles Staddon, J. Scientific Method: How Science Works, Fails to Work, and Pretends to Work (ISBN 978-1-1382-9536-0) Helliwell, J. R. Skills for Scientific Life (ISBN 978-1-4987-6875-7) MacRitchie, F. Scientific Research as a Career (ISBN 978-1-4398-6965-9)
Today's Medical Assistant: Clinical And Administrative Procedures
by Kathy Bonewit-West Sue A. Hunt Edith ApplegateMedical assistants, for many years an integral part of most physicians' staff, now fulfill an ever-expanding and varied role in the medical office, both clinically and administratively. With increased responsibilities, however, comes a greater need for professional knowledge and skills.
Today's Medical Assistant: Clinical and Administrative Procedures
by Kathy Bonewit-West Sue HuntBringing together comprehensive, easy-to-read coverage of medical assisting competencies and a solid foundation of anatomy and physiology, Today's Medical Assistant: Clinical and Administrative Procedures, 4th Edition provides everything you need to successfully begin a career as a medical assistant. <p><p>This hands-on guide uses easy-to-follow language and detailed visuals to walk you through all the medical knowledge, procedures, and skills you need for success in today's fast-paced medical office. Cutting-edge content is organized around medical assisting standards and competencies, supplemented throughout with a wide assortment of engaging learning tools and activities that help you to fully understand and demonstrate those competencies. <p><p>The 4th Edition features enhanced coverage of healthcare law, certification, electronic health records, motivational interviewing, office management, and more, as well as additional procedures to address behavior-based competencies and expanded sample certification exams online.
Today's Students, Tomorrow's Doctors: Bk.2, Further Detection and Management of Physical Disease
by Kathy Feest Karen ForbesThis work includes forewords by Sir Kenneth Calman, Lynn Calman, and Rita Charon. Respectively Vice-Chancellor and Warden, University of Durham and former Chief Medical Officer for England; Research Associate, School of Nursing, Midwifery and Social Work, University of Manchester; Professor of Clinical Medicine, College of Physicians and Surgeons, University of Columbia, New York, USA. "Today's Students, Tomorrow's Doctors" offers actual accounts of life as a trainee junior doctor in the health service today. It is an intriguing read which includes student contributions that are witty, humorous, poignant and sometimes harrowing. With a strong focus on the personal, powerful and emotional experiences of trainee and junior doctors, this unique book challenges medical educators to understand the demands placed on graduates and will stimulate change and curriculum development. The book is also a great reference for medical students - preparing them for the realities of ward life. It aids in developing an understanding of the skills and experience required to survive and thrive in the healthcare environment. This is an invaluable resource for medical educators in both work-based and university roles. It will also be of great interest to healthcare managers and curriculum developers and shapers. 'A joy to read, full of hope. We were delighted, surprised and at times concerned. Delighted because of the issues raised and the sophisticated ways in which students responded to the challenges; surprised at the range of issues raised and the obvious importance of relationships in the clinical setting; finally concerned at some of the attitudes which were commented on, especially of senior staff, and on the adequacy of preparation for house officer posts. This book is inspirational and should be read by all who have any part to play in the education of doctors.' - Sir Kenneth Calman and Lynne Calman, in their Foreword. 'Extraordinary. This is autobiographical insight at its most powerful, for it leads to transformative growth and true learning. I am first of all impressed with the emotional valence of these writings. They reflect the students' interior states of sadness, empathy, and awe as they bear witness to patients' suffering. The essays reflect a fresh calculus of sickness and duty [and] give me great and glad hope that our doctors of the future will be efficient with the forms of medicine as well as courageous in braving their contact with the ill, with the dying, with the humans who confront them evermore seeking care, seeking comfort, seeking their full capacity to heal.' - Rita Charon, in her Foreword.
Today’s Medical Assistant: Clinical and Administrative Procedures
by Kathy Bonewit-West Sue A. Hunt Edith ApplegateThis textbook provides up-to-date information in both the administrative and clinical areas, and it incorporates current trends in technology. It provides a format for the achievement of professional competency in skills performed in the medical office, and the understanding of their application to real-life or on-the-job situations.
Todes- und Suizidwünsche: Ethische Herausforderungen in der Pflege (essentials)
by Annette Riedel Anna-Henrikje Seidlein Karen KlotzPflegefachpersonen sind oft erste Ansprechpartner*innen, wenn pflegebedürftige Menschen einen Todes- oder Suizidwunsch äußern. Solche Äußerungen sind tiefgreifend und vielschichtig. Sie erfordern sorgfältige Abklärung und professionelle, einfühlsame Begleitung. Gleichzeitig bringen diese Situationen komplexe ethische Fragestellungen mit sich, die Pflegefachpersonen vor moralische Herausforderungen stellen können. Besonders der Wunsch nach Suizidassistenz verlangt eine reflektierte Gewissensentscheidung. Das essential beleuchtet die ethischen Dimensionen der Thematik und zeigt Wege für einen verantwortungsvollen Umgang mit Todes- und Suizidwünschen, Suizidassistenz und Suizidprävention in der Pflegepraxis auf.
Todesfeststellung und Leichenschau für Hausärzte: medizinisch, juristisch, verwaltungstechnisch richtig handeln
by Burkhard Madea Klaus WeckbeckerGriffbereit - prägnant – übersichtlich. Das Wichtigste für den Hausarzt. Alle notwendigen Informationen zur praktischen Durchführung der Leichenschau – medizinisch, juristisch, verwaltungstechnisch. Checkliste zur LeichenschauLinks zu den wichtigsten GesetzestextenAbrechnungshinweise Inklusive Verhaltensregeln bei speziellen Fragestellungen: Verdacht auf iatrogenen Todesfall, Zuständigkeiten, Melde- und Schweigepflichten, Zusammenarbeit mit Polizei und Justiz …
Todesvorstellung von Heilberuflern: Methoden der Literaturzusammenfassung (Palliative Care und Forschung)
by Martin W. Schnell Christine Dunger Christian Schulz-QuachHeilberufler, d.h. Ärzt*innen, Pflegende und Vertreter anderer Professionen, die in der Versorgung sterbender Menschen und deren Angehöriger tätig sind, haben Vorstellungen vom Tod ausgebildet. Diese leiten die Behandlungsweise von sterbenden Menschen, da sie Antworten auf fundamentale Fragen geben. Was ist der Tod? Wann tritt ein Mensch in seine letzte Lebensphase ein? Todesvorstellungen sind meist Mischkonzepte. Wissenschaft, Berufserfahrung, Mythologie, Religion, allgemeine Werte gehen in sie ein. Die vorliegende Publikation erforscht die Todesvorstellungen von Heilberuflern und stellt sie in ihrer Diversität dar. Der Band führt dabei Methoden der Literaturzusammenfassung vor, die von fortgeschrittenen Studierenden, Doktoranden und jungen Forscher*innen verwendet werden können, um einen relevanten Forschungsstand zu dokumentieren. Eine wissenschaftshistorische und methodische Reflexion fundiert diese Vorstellung.
Todo lo que necesitas saber sobre el virus del Zika
by Dr Christopher Maloney N. D. Ana Rodríguez Díaz¿Te da miedo el virus del Zika? ¿Todavía piensas que se propaga sobre todo por los mosquitos? ¿Sabes que hay otros animales que albergan el Zika? ¿Tienes idea de cuánto tiempo lo podemos tener en el cuerpo y contagiar a otras personas? El Dr. Maloney explica de forma sencilla las investigaciones más recientes sobre la propagación del Zika y sobre el hecho de que el virus produzca efectos secundarios graves, como anomalías genéticas y parálisis. Ofrece una posible explicación sobre por qué algunos bebés se ven afectados y otros no. El Zika es al mismo tiempo más y menos peligroso de lo que nos han contado. Aquí puedes aprender rápidamente a mantener a tu familia a salvo del Zika.
Toegepast rekenen
by Ron GroothuisAls docent rekenen huldigde Ron Groothuis het principe dat iedereen kan rekenen en dat rekenen spannend, leuk en uitdagend is. Wat leerlingen belemmert, is het idee dat ze niet kunnen rekenen. Niets is echter minder waar! Samen met zijn leerlingen ontwikkelde Groothuis een lesprogramma waarin de dagelijkse maar ook de spectaculaire kanten van het rekenen naar voren kwamen. 'Toegepast rekenen voor zorg en verpleging' is de neerslag van dit lesprogramma. Het stelt de leerlingen in staat om in en naast de lessen de stof zelfstandig te leren ontdekken en beheersen. Alle belangrijke rekenelementen waar de student later in de praktijk mee te maken krijgt, worden geoefend. Ron Groothuis volgde de opleidingen NLO Maatschappij/Huishoudkunde en MO-A Pedagogiek. Hij geeft sinds 1984 trainingen en scholing in de zorgsector. Tevens is hij werkzaam in de zorg in diverse staf- en managementfuncties. Kijk voor de tekst online, studie-links, meer opdrachten en samenvattingen op www. studiecloud. nl
Together, Closer: The Art and Science of Intimacy in Friendship, Love, and Family
by Giovanni FrazzettoFor readers of Oliver Sacks and Stephen Grosz, a wondrous, deeply felt book that explores intimacy through the stories of eight relationships, from the author of Joy, Guilt, Anger, Love The bonds we are capable of feeling toward other people—how we know and belong to one another—provide fascinating glimpses into the intricacies of human behavior. Intimacy is that moment when our true identity is revealed to another, when traumas, fears, and ambitions are shared. Through the ordinary stories of eight relationships, Giovanni Frazzetto has woven an extraordinary narrative of togetherness. He shares the details of romantic partners trapped in a long cycle of attraction and rejection, a single woman who finds herself deep in a fictional relationship with a boyfriend she has invented out of frustration with her love life, and a couple absorbed in a years-long clandestine affair. But intimacy can also extend beyond romantic encounters: coping with the loss of a loved one, dealing with overbearing or emotionally distant parents, or celebrating the joys and comforts of our dearest friends. In Together, Closer, Frazzetto unravels the components of intimacy in all of these relationships, illuminating the mysteries, challenges, and pleasures of intimacy through a brilliant mix of storytelling and science. Praise for Giovanni Frazzetto’s Joy, Guilt, Anger, Love: “In Frazzetto’s book, the Italian researcher and writer offers a fine primer on six emotions plus empathy. But before diving into the biology of each emotion (the role of the amygdala in fear and of serotonin reuptake in grief), he inspects his target through the lenses of psychology, philosophy, art, and personal experience. What you see is that poetry offers more insight into our feelings than does neuroanatomy or biochemistry.” —The Washington Post
Together: A Memoir of a Marriage and a Medical Mishap
by Judy GoldmanA routine procedure left novelist, memoirist, and poet Judy Goldman's husband paralyzed. Together is her unforgettable account of the struggle to regain their "normal" life and a nuanced portrait of a marriage tested.When Judy Goldman's husband of almost four decades reads a newspaper ad for an injection to alleviate back pain, the outpatient procedure sounds like the answer to his longtime backaches. But rather than restoring his tennis game, the procedure leaves him paralyzed from the waist down--a phenomenon none of the doctors the family consults can explain. Overnight, Goldman's world is turned upside down. Though she has always thought of herself as the polite, demure wife opposite her strong, brave husband, Goldman finds herself thrown into a new role as his advocate, navigating byzantine hospital policies, demanding and refusing treatments, seeking solutions to help him win back his independence. Along the way, Goldman flashes back to her memories of their life together. As she tries envision her family's future, she discovers a new, more resilient version of herself. Together is a story of the life we imagine versus the life we lead--an elegant and empathetic meditation on partnership, aging, and, of course, love.
Together: Loneliness, Health and What Happens When We Find Connection
by Vivek H. Murthy'The most important book you'll read this year.' DANIEL H. PINK, author of Drive'Together stands with Atul Gawande's classic, Being Mortal.' MALCOLM GLADWELL, author of Outliers'A welcome beacon towards meaningful connection' ARIANNA HUFFINGTON, author of Thrive'Fascinating, moving and essential reading.' ATUL GAWANDE, author of Being Mortal'This book is a gift' SUSAN CAIN, author of Quiet'Exactly what the doctor ordered' ANGELA DUCKWORTH, author of GritThe world seems more connected than ever, and yet loneliness is at epidemic levels. But what effect is it having on us, and how can we treat it - even at a distance?When Obama appointed him Surgeon General of the United States, Dr Vivek Murthy observed the growing health crisis of isolation first-hand. In this ground-breaking book, he traces the roots of the problem, and shows how loneliness lies behind some of our greatest personal and social challenges, from anxiety and depression to addiction and violence. But he also reveals the cure. His search led him to talk to doctors, scientists, parents and community members around the world. The solutions are deceptively simple and easily applicable - and the effects are transformative. And one thing is clear: real human connection is a medical necessity if we want to stay healthy. We can all create it, and benefit from it, and it is more urgent than ever that we start now.
Together: The Healing Power of Human Connection in a Sometimes Lonely World
by Vivek H MurthyIn this groundbreaking book, Former Surgeon General of the United States, Vivek Murthy argues that loneliness is the underpinning to the current crisis in mental wellness and is responsible for the upsurge in suicide, the opioid epidemic, the overuse of psych meds, the over-diagnosing and pathologizing of emotional and psychological struggle. <P><P>The good news is that social connection is innate and a cure for loneliness. In Together, the former Surgeon General will address the importance of community and connection and offer viable and actionable solutions to this overlooked epidemic. <P><P><b>A New York Times Bestseller</b>
Toilet as Business for the Hygiene of the Chinese Community in Colonial Hong Kong
by Yuk-sik ChongThis book analyses how public toilets were provided by the government and local business in Hong Kong between the 1860s and 1930s through a process that was embedded in class and racial politics. Addressing public toilet provision from a political economy perspective, it focuses on the interplay of the cross-border night soil business between Hong Kong and China’s silk producing area; the silk market between China and Colonial powers; the Hong Kong land market between the colonial government and Chinese business; and how these factors jointly produced a network of toilets in the colony. As the book shows, the commercial viability of toilets created multiple logics and a new moral geography; further, exploring the topic can help us gain a better understanding of how urban governance functioned in colonies and how it intertwined with economic contingencies within a global economic system. The intended readership includes academics and members of the general public with an interest in colonialism, public infrastructures, public health, government–business relations, and urban governance.
Toledo State Hospital (Images of America)
by Kimberly BrownleeThe Toledo State Hospital opened in 1888, and its design and healing approach were revolutionary for the time. First in the country built entirely on the "cottage model," its plan was intended to create a homelike atmosphere in a beautifully manicured landscape. Treatment methods were based on the "moral treatment" philosophy, the belief that calming surroundings with nutritious food, productive work, and diversion would help the disturbed mind to heal. Over the years, facilities were expanded to serve a burgeoning patient population, and medications and treatments evolved. In the 1950s, however, the population began a steady decline due to the advent of services in the community and to advances in psychotropic drugs. As the old buildings were emptied, they were demolished, and all were gone by 1981.
Toll-Like Receptors
by Luke A.J. O'Neill Claire E. MccoyIn addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections highlighting tips on troubleshooting and avoiding known pitfalls. Versatile and cutting-edge, Toll-Like Receptors: Methods and Protocols provides an ideal manual for a wide range of biologists and medical researchers studying these vital components of the immune system.
Toll-Like Receptors: Methods and Protocols (Methods in Molecular Biology #2700)
by Francesca Fallarino Marco Gargaro Giorgia ManniThis volume provides methods on the role of TLRs in immune responses and on the various approaches targeting different TLRs in cancer, autoimmunity and in vaccine development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Toll-Like Receptors: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Toll-like Receptors in Health and Disease (Handbook of Experimental Pharmacology #276)
by Vijay KumarThe current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans.The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.