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Toll-like Receptors: Roles in Infection and Neuropathology
by Tammy KielianMammalian Toll-like receptors (TLRs) were first identified in 1997 based on their homology with Drosophila Toll, which mediates innate immunity in the fly. In recent years, the number of studies describing TLR expression and function in the nervous system has been increasing steadily and expanding beyond their traditional roles in infectious diseases to neurodegenerative disorders and injury. Interest in the field serves as the impetus for this volume in the Current Topics in Microbiology and Immunology series entitled "Toll-like receptors: Roles in Infection and Neuropathology". The first five chapters highlight more traditional roles for TLRs in infectious diseases of the CNS. The second half of the volume discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands. Several conceptual theories are introduced in various chapters that deal with the dual nature of TLR engagement and whether these signals favor neuroprotective versus neurodegenerative outcomes. This volume should be informative for both experts as well as newcomers to the field of TLRs in the nervous system based on its coverage of basic TLR biology as well as specialization to discuss specific diseases of the nervous system where TLR function has been implicated. A must read for researchers interested in the dual role of these receptors in neuroinfection and neurodegeneration.
Tomatoes and Tomato Products: Nutritional, Medicinal and Therapeutic Properties
by V. R. PreedyThe contributors to this book are authors of international and national standing, leaders in the field and trendsetters. The book covers emerging fields of science and important discoveries relating to tomatoes and related products. This represents a one-stop shopping of material related to tomatoes. This book will be essential reading for plant sc
Tommy Douglas
by Dave MargoshesDuring the 17 years he was premier of Saskatchewan, Tommy Douglas changed the face of his province. He then served for 10 years as first leader of the federal New Democratic Party. Today he is recognized as the "father of medicare." In 2004, CBC TV viewers voted him the "Greatest Canadian."
Tomographic Methods in Nuclear Medicine: Physical Principles, Instruments, and Clinical Applications
by Bhagwat D. AhluwaliaThis publication is a compendium of physical principles, system descriptions, instrument quality assurance, and clinical applications of extant tomographic methods in nuclear medicine. Written by an expert in this pertinent field, each chapter deals with the topics in a comprehensive fashion to provide a ready reference of all the work done on the subject and an estimate of the future utilization. Descriptions of methods available to nuclear medicine for tomographic viewing include positron emission, single photon emission, and planar tomography. This is an excellent resource volume of general applicability for nuclear medicine physicians, nuclear medicine scientists, and researchers in organ imaging and processing techniques.
Tomography of the Earth's Crust: From Geophysical Sounding to Real-Time Monitoring
by Michael Weber Ute MünchThe research work on the topic of ''Tomography of the Earth's Crust: From Geophysical Sounding to Real-Time Monitoring'' has focused on the development of cross-scale multiparameter methods and their technological application together with the development of innovative field techniques. Seismic wave field inversion theory, diffusion and potential methods were developed and optimized with respect to cost and benefit aspects. This volume summarizes the scientific results of nine interdisciplinary joint projects funded by the German Federal Ministry of Education and Research in the framework of the Research and Development Program GEOTECHNOLOGIEN. Highlights and innovations presented cover many length scales and involve targets ranging from applications in the laboratory, to ground water surveys of heterogeneous aquifer, geotechnical applications like tunnel excavation, coal mine and CO2 monitoring and the imaging and monitoring of tectonic and societally relevant objects as active faults and volcanoes. To study these objects, the authors use the full spectrum of geophysical methods (ultrasonics, seismic and seismology, electromagnetics, gravity, and airborne) in combination with new methods like seismic interferometry, diffuse wave field theory and full-wave-form inversion in 3D and partially also in 4D. Geophysical Sounding to Real-Time Monitoring'' has focused on the development of cross-scale multiparameter methods and their technological application together with the development of innovative field techniques. Seismic wave field inversion theory, diffusion and potential methods were developed and optimized with respect to cost and benefit aspects. This volume summarizes the scientific results of nine interdisciplinary joint projects funded by the German Federal Ministry of Education and Research in the framework of the Research and Development Program GEOTECHNOLOGIEN. Highlights and innovations presented cover many length scales and involve targets ranging from applications in the laboratory, to ground water surveys of heterogeneous aquifer, geotechnical applications like tunnel excavation, coal mine and CO2 monitoring and the imaging and monitoring of tectonic and societally relevant objects as active faults and volcanoes. To study these objects, the authors use the full spectrum of geophysical methods (ultrasonics, seismic and seismology, electromagnetics, gravity, and airborne) in combination with new methods like seismic interferometry, diffuse wave field theory and full-wave-form inversion in 3D and partially also in 4D. 2 monitoring and the imaging and monitoring of tectonic and societally relevant objects as active faults and volcanoes. To study these objects, the authors use the full spectrum of geophysical methods (ultrasonics, seismic and seismology, electromagnetics, gravity, and airborne) in combination with new methods like seismic interferometry, diffuse wave field theory and full-wave-form inversion in 3D and partially also in 4D.
Tomorrow Will Be A Good Day: My Autobiography - The Sunday Times No 1 Bestseller
by Captain Tom MooreEmbark on an enchanting journey into our country's past hundred years through the remarkable life of Captain Sir Tom MooreTHE NO. 1 SUNDAY TIMES BESTSELLER'A wonderful life story with lessons for us all . . . beautifully written' DAILY TELEGRAPH'Gloriously enthralling' DAILY MAIL__________Captain Sir Tom Moore's story is all our stories . . .Born at the tail end of the Spanish flu epidemic, Tom Moore was raised in the Yorkshire Dales by a loving family that had not escaped tragedy. Yet when the clouds of war threatened, Tom raised his hand and joined up to fight.The Second World War took him to the Far East, where his can-do spirit was forged. Whether fighting for his life in Burma or helming a firm back home, racing motorbikes or raising a family, he always sought to do his very best. To make a difference to those around him.Captain Tom's story is that of our parents and our grandparents.It is the story of the past hundred years here in Britain.__________'Engaging . . . His upbeat nature shines through and reminds us how much worse this year would have been without him' Evening Standard'A wonderful read. Captain Tom is a beacon of light, and hope, and positivity' Piers Morgan, Life Stories, ITV'A great book' Good Morning Britain'A beautiful book. We have so much to learn from Captain Sir Tom' Chris Evans, Virgin Radio 'Fascinating. It's the life story of an ordinary man who is extraordinary' Michael Ball, BBC Radio 2
Tomorrow's Cures Today?: How to Reform the Health Research System
by Donald R ForsdykeDiscussing the laws in the current research funding decision process, the author suggests ways to improve future funding of health research systems. Chapters recount ways of raising funds, the tragic way authorities improperly introduced diptheria immunization, consideration of how the peer review system evolved in response to massive infusion of f
Tomorrow's Healthcare by Nano-sized Approaches: A Bold Future for Medicine
by Paula Veronica Messina Benedini Luciano Damian PlacenteNanomedicine, a scientific branch of nanotechnology that operates on the same scale as biology, offers the possibility of influencing the healing process from inside of the body by manipulating the matter at cellular or molecular levels. Throughout this book, current healing approaches based on this revolutionary new technology are summarized from a scientific assessment. The aim of the authors is to give, through select examples, a deep insight to nanotechnology status and the great progress that its rigorous application will bring to human health. The authors' commitment is to broaden the vision of health professionals who will eventually be the future users of this knowledge.
Tomosynthesis Imaging (Imaging in Medical Diagnosis and Therapy)
by Ingrid Reiser Stephen GlickAn innovative, three-dimensional x-ray imaging technique that enhances projection radiography by adding depth resolution, Tomosynthesis Imaging explores tomosynthesis, an emerging limited-angle tomographic imaging technology that is being considered for use in a range of clinical applications, and is currently being used for breast cancer screening
Toms River
by Dan Fagin<P>The riveting true story of a small town ravaged by industrial pollution, Toms River melds hard-hitting investigative reporting, a fascinating scientific detective story, and an unforgettable cast of characters into a sweeping narrative in the tradition of A Civil Action, The Emperor of All Maladies, and The Immortal Life of Henrietta Lacks. <P>One of New Jersey's seemingly innumerable quiet seaside towns, Toms River became the unlikely setting for a decades-long drama that culminated in 2001 with one of the largest legal settlements in the annals of toxic dumping. <P>A town that would rather have been known for its Little League World Series champions ended up making history for an entirely different reason: a notorious cluster of childhood cancers scientifically linked to local air and water pollution. <P>For years, large chemical companies had been using Toms River as their private dumping ground, burying tens of thousands of leaky drums in open pits and discharging billions of gallons of acid-laced wastewater into the town's namesake river. <P>In an astonishing feat of investigative reporting, prize-winning journalist Dan Fagin recounts the sixty-year saga of rampant pollution and inadequate oversight that made Toms River a cautionary example for fast-growing industrial towns from South Jersey to South China. <P>He tells the stories of the pioneering scientists and physicians who first identified pollutants as a cause of cancer, and brings to life the everyday heroes in Toms River who struggled for justice: a young boy whose cherubic smile belied the fast-growing tumors that had decimated his body from birth; a nurse who fought to bring the alarming incidence of childhood cancers to the attention of authorities who didn't want to listen; and a mother whose love for her stricken child transformed her into a tenacious advocate for change. <P>A gripping human drama rooted in a centuries-old scientific quest, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who refused to keep silent until the truth was exposed. <P><b> Winner of the Pulitzer Prize</b> <P><b> Winner of The New York Public Library's Helen Bernstein Book Award </b> <P><b>A New York Times Bestseller</b>
Tongue Diagnosis In Chinese Medicine, Revised Edition
by Giovanni MaciociaTongue diagnosis is one of the most precious diagnostic methods in Chinese medicine. Its basic elements are relatively easy to learn, but like many aspects of Chinese medicine, it is constantly enriched by clinical practice. No matter how long one has been practicing, there will always be something new to learn. In fact, in every lecture I give on tongue diagnosis there is always at least one student who describes a type of tongue that I have never seen before!
Tongue Image Analysis
by David Zhang Hongzhi Zhang Bob ZhangThis is the first book offering a systematic description of tongue image analysis and processing technologies and their typical applications in computerized tongue diagnostic (CTD) systems. It features the most current research findings in all aspects of tongue image acquisition, preprocessing, classification, and diagnostic support methodologies, from theoretical and algorithmic problems to prototype design and development of CTD systems. The book begins with a very in-depth description of CTD on a need-to-know basis which includes an overview of CTD systems and traditional Chinese medicine (TCM) in order to provide the information on the context and background of tongue image analysis. The core part then introduces algorithms as well as their implementation methods, at a know-how level, including image segmentation methods, chromatic correction, and classification of tongue images. Some clinical applications based on these methods are presented for the show-how purpose in the CTD research field. Case studies highlight different techniques that have been adopted to assist the visual inspection of appendicitis, diabetes, and other common diseases. Experimental results under different challenging clinical circumstances have demonstrated the superior performance of these techniques. In this book, the principles of tongue image analysis are illustrated with plentiful graphs, tables, and practical experiments to provide insights into some of the problems. In this way, readers can easily find a quick and systematic way through the complicated theories and they can later even extend their studies to special topics of interest. This book will be of benefit to researchers, professionals, and graduate students working in the field of computer vision, pattern recognition, clinical practice, and TCM, as well as those involved in interdisciplinary research.
Tongue Lesions: Diagnostic Challenges and Therapeutic Strategies
by Mahmoud F. SakrThe book offers in a single resource the whole coverage of different diseases and lesions, congenital or acquired, of the tongue, along with a complete spectrum of surgical techniques that can be used to achieve the best functional and aesthetic results.In addition to tongue embryology, surgical anatomy, histology and physiology, the book explores the differential diagnosis of congenital anomalies of the tongue and lingual lesions, as well as the most recent advances in surgical management (resection, reconstruction and surgical management of the neck in patients with tongue cancer). The volume includes unique chapters about tongue replantation and tongue allo-transplantation. Richly illustrated, this book provides an indispensable source of knowledge to all specialists and trainees entrusted with the care of patients suffering from tongue lesions.
Tongue-Tied: How a Tiny String under the Tongue Impacts Nursing, Speech, Feeding and More
by Richard BaxterChances are, you or someone you know is affected by a tongue-tie. Common, yet little understood, tongue-ties can lead to a myriad of problems, including difficulty when nursing, speaking or eating. In the most crucial and formative parts of children's lives, tongue-ties have a significant effect on their well-being. Many parents and professionals alike want to know what can be done, and how best to treat these patients and families. And now, there are answers. Tongue-Tied: How a Tiny String Under the Tongue Impacts Nursing, Feeding, Speech, and More is an exhaustive and informative guide to this misunderstood affliction. Along with a team of medical specialists, author Dr. Richard Baxter demystifies tongue ties and spells out how this condition can be treated comprehensively, safely and comfortably. Starting with a broad history of tongue-ties, this invaluable guide covers 21st-century assessment techniques and treatment options available for tethered oral tissues. Various accounts of patient challenges and victories are prominently featured as well. With the proper diagnosis and treatment, tethered oral tissues can be released with minimal discomfort, resulting in improvements during nursing, speaking, and feeding, while also reducing the incidence of dental issues, headaches, and even neck pain for children through adults. Aimed at both parents and professionals, Tongue-Tied encourages those affected while providing reassuring and valuable information. Dr. Baxter and his qualified team have pooled their expertise to make a difference in the lives of people.
Too Conscientious: The Evolution of Ethical Challenges to Professionalism in the American Medical Marketplace (The International Library of Bioethics #94)
by Douglas E. LemleyThis book addresses the fundamental conflict of interest that physicians face in their daily work lives between the ethics of proper medical care versus the demands of standard business practices. However, unlike other books of this sort, this one places direct responsibility for this ethical dilemma upon the shoulders of physicians themselves. Taking ethical, legal, and business perspectives into account, the book traces the historically evolving response of American physicians to ever-increasing business interests within the profession. These financial concerns now have become intrinsic not only to the practice of medicine but seemingly also to the character of a growing segment of its practitioners. The book offers a plea for a change to a more socialized healthcare system as used in other advanced nations.
Too Ill to Talk?: User Involvement in Palliative Care
by Penny Rhodes Neil SmallUser involvement has become an important part of health policy initiatives during the last decade, but how realistic is the concept and do all users want to be involved? This book brings the voices of people with serious illness, and those caring for them, into debate about how far health and social care services can reflect the views of users.Providing an overview of the literature on user involvement, the book looks at the policy and professional context within which user involvement is undertaken, in particular user involvement in pallative care. The authors discuss two key concepts - palliative care and empowerment - and analyse the role of self-help groups and new information and communication technologies in this context. The book focuses on the detailed narratives of people coping with three life-threatening illnesses - cystic fibrosis, multiple sclerosis and motor neurone disease - and in this way the views and experiences of the 'user' are brought into play to critique current policy and practice.Addressing a current health services issue in a refreshingly critical manner the text challenges the assumption that user involvement is either easy to achieve or that it is necessarily welcomed by all parties. It will be valuable reading for students on health studies courses, health professionals and policy makers in health and social care.
Too Young for Cancer: One Woman's Battle for a Diagnosis and a Fighting Chance
by Katie ColemanA stage IV cancer survivor reflects on treatment and recovery in this inspiring memoir that reveals the biases of the healthcare system—and the power of community. New Year's Eve 2020 was supposed to be a turning point to better days for twenty-nine-year-old Katie Coleman. Instead, she found herself in the ER processing the earth-shattering news of a stage IV cancer diagnosis, one that had come after years of being assured she was "too young for cancer&” and a repeated misdiagnosis of anxiety.Too Young for Cancer tells the story of Katie&’s journey from diagnosis with an ultrarare cancer through treatment, recovery, and a life-altering shift in perspective. Katie starts her journey shy, timid, and frightened of an intimidating medical world, but as she learns how to advocate for herself, she faces her own mortality with bravery and finds herself at top cancer institutions arguing her case for a radical and high-risk surgery that could change her life forever.With support from her husband, innovative doctors, and a diverse community of cancer survivors, Katie finds her life&’s purpose to advocate not only for herself but also for others who are fighting just as hard for their lives.Too Young for Cancer highlights the absolute best and worst in healthcare and uncovers the silver linings and beauty of humanity filling the space in between.
Toolbox Resilienz: Skills für den Umgang mit kritischen Situationen beim Lernen und im Klinikalltag (essentials)
by Martina Kahl-ScholzResilienz ist mittlerweile als Schlagwort überall da zu hören, wo Menschen sich Herausforderungen gegenübersehen – egal, ob das für den privaten oder beruflichen Bereich, für einzelne Personen, Teams oder ganze Unternehmen gilt. Resilienz ist aber kein Allheilmittel, das man sich im Vorbeigehen aneignen und dann jederzeit anwenden kann. Vielmehr beschreibt Resilienz eine innere Haltung, die sich allgemeinhin aus mehreren Bausteinen zusammensetzt – genau das gilt für die ureigene Widerstandskraft, um die es in diesem essential gehen soll, auch.Aus eigener Erfahrung beschreibt die Autorin, welche Herausforderungen das Medizinstudium und der spätere klinische Alltag bereithalten können – und dass man zwar theoretisch darauf vorbereitet sein kann, die praktische Erfahrung aber doch die Vorstellung davon meistens um Längen schlägt. Dieses essential soll eine kleine Hilfestellung bieten, um durch das Näherrücken an das Thema „Resilienz&“ einige Skills zu vermitteln, die das Lernen erleichtern und auch den Umgang mit kritischen Situationen im Klinikalltag einfacher machen. Damit hilft man als angehender Arzt/angehende Ärztin nicht nur sich selbst, sondern auch den Patienten, die man behandelt.
Toole's Cerebrovascular Disorders
by José Biller E. Steve Roach Kerstin BettermannToole's Cerebrovascular Disorders, was the first modern book devoted to the care of the stroke, originally published more than 40 years ago. Drs. E. Steve Roach, Kerstin Bettermann, and José Biller have completely revised and updated sixth edition of the highly respected standard for stroke diagnosis and treatment, adding chapters on genetics, pregnancy-related stroke, and acute treatment. The practical focus of the book has not changed, retaining its emphasis on bedside diagnosis and treatment. Easily accessible for both stroke specialists and residents, the sixth edition has been modernized to keep pace with the rapid expansion of knowledge in stroke care and includes evidence-based recommendations, the latest technology and imaging, and risk factors. The text is supplemented with more than 200 images, many in color. E. Steve Roach, MD, FAAN, FAHA, is Professor of Pediatrics and Neurology and Director of the Division of Child Neurology at The Ohio State University College of Medicine, Columbus, Ohio. Kerstin Bettermann, MD, PhD, is Assistant Professor of Neurology at Penn State College of Medicine, Hershey, Pennsylvania. José Biller, MD, FACP, FAAN, FAHA, is Professor of Neurology and Neurosurgery and Chairman of the Department of Neurology at Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.
Toolkit kwetsbare ouderen: Screeningsinstrument en evidence-based zorgplannen voor kwetsbare ouderen in de eerste lijn
by Nienke BleijenbergOuderen willen graag zo lang mogelijk zelfstandig blijven wonen. Met het toenemen van de leeftijd kunnen zij echter door gezondheidsproblemen te maken krijgen met beperkingen in hun dagelijks functioneren. Dit kan leiden tot een verminderde kwaliteit van leven, een toenemende zorgvraag en andere negatieve gezondheidsuitkomsten. Het is belangrijk dit verhoogde risico op achteruitgang in het dagelijks functioneren tijdig te signaleren. Met name zorgverleners in de eerste lijn, zoals verpleegkundigen en huisartsen, spelen hierin een belangrijke rol. Hun taak is in een vroeg stadium deze ouderen te identificeren en vervolgens zorg op maat te leveren om achteruitgang te verminderen of tegen te gaan. De ‘Toolkit kwetsbare ouderen’ beschrijft een methode waarmee zorgverleners in de eerste lijn een omslag kunnen maken naar proactieve evidence-based ouderenzorg. De toolkit geeft handvatten voor het identificeren van mogelijk kwetsbare ouderen met behulp van dertien evidence-based zorgplannen. De methode is onder ruim 3000 ouderen wetenschappelijk onderzocht. Ouderen die zorg volgens deze methode ontvingen lieten na één jaar minder achteruitgang zien dan ouderen die de bestaande zorg ontvingen. De werkwijze werd positief ontvangen door ouderen, huisartsen en praktijkverpleegkundigen. De toolkit is bestemd voor studenten verpleegkunde, studenten die een aanvullende opleiding volgen voor in de eerste lijn of ouderenzorg, maar is zeker ook geschikt voor verpleegkundigen in de eerste lijn zoals praktijkverpleegkundigen en wijkverpleegkundigen.
Tools and Techniques in Radiation Biophysics
by Ashima PathakThis textbook describes the study of radiation, covering the basic concepts and their advanced applications, and highlights the handling of radioisotopes and radiation measurements using various instruments. The book also focuses on the effects and up-to-date applications of radiation on biological systems and their use in diagnosing and treating various diseases. Chapters provide an easy understanding of the subject matter with the help of self-explanatory, well-illustrated figures and easy-to-grasp language. “Tools and Techniques in Radiation Biophysics” is designed for undergraduate and post-graduate studying radiation Biophysics as one of the major courses in medical physics, nuclear medicine, biophysics, and other applied sciences. The multi-disciplinary approach of this book facilitates learning and a deep understanding of the concepts and helps the readers develop an interest in the subject so that they can pursue their careers efficiently in this field. Researchers and lecturers will value this book to enhance their knowledge and clarify queries.
Tools and Trends in Bioanalytical Chemistry
by Lauro Tatsuo Kubota José Alberto Fracassi da Silva Marcelo Martins Sena Wendel Andrade AlvesThis textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis.Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.
Tools and the Organism: Technology and the Body in Ancient Greek and Roman Medicine
by Colin WebsterThe first book to show how the concept of bodily organs emerged and how ancient tools influenced conceptualizations of human anatomy and its operations. Medicine is itself a type of technology, involving therapeutic tools and substances, and so one can write the history of medicine as the application of different technologies to the human body. In Tools and the Organism, Colin Webster argues that, throughout antiquity, these tools were crucial to broader theoretical shifts. Notions changed about what type of object a body is, what substances constitute its essential nature, and how its parts interact. By following these changes and taking the question of technology into the heart of Greek and Roman medicine, Webster reveals how the body was first conceptualized as an “organism”—a functional object whose inner parts were tools, or organa, that each completed certain vital tasks. He also shows how different medical tools created different bodies. Webster’s approach provides both an overarching survey of the ways that technologies impacted notions of corporeality and corporeal behaviors and, at the same time, stays attentive to the specific material details of ancient tools and how they informed assumptions about somatic structures, substances, and inner processes. For example, by turning to developments in water-delivery technologies and pneumatic tools, we see how these changing material realities altered theories of the vascular system and respiration across Classical antiquity. Tools and the Organism makes the compelling case for why telling the history of ancient Greco-Roman medical theories, from the Hippocratics to Galen, should pay close attention to the question of technology.
Tools for Evaluating the Metropolitan Medical Response System Program: Phase I Report
by Committee on Evaluation of the Metropolitan Medical Response ProgramInformation on the Tools for Evaluating the Metropolitan Medical Response System Program
Tools for Teaching Comprehensive Human Sexuality Education
by Dominick Splendorio Lori ReichelA hands-on resource filled with interactive activities to engage students' thinking and skill development This book contains ready-to-use lesson plans referencing both the National Sexuality Education Standards and the National Health Education Standards, and is arranged into chapters by the seven topic areas outlined in the National Sexuality Education Standards. These include: anatomy and physiology, puberty and adolescent development, identity, pregnancy and reproduction, sexually transmitted infections, healthy relationships, and personal safety. These dynamic "pick and choose" lessons and activities have been field-tested in classrooms and workshops by the authors, who are recognized experts in this area. Many of the lessons contain an opening activity to immediately engage students, followed by student-centered learning experiences such as case studies, simulations, real-life scenarios, self-assessments, journals, and individual and group projects/presentations. Features lessons that incorporate the essential knowledge and skills to empower students to make healthy decisions related to their sexual health Includes performance indicators detailed what students should know and be able to do by the end of grades eight and twelve Offers supplementary web resources and assessment projects, as well as "Home-School Connection" assignments to support family communication about sexuality