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Topical and Transdermal Drug Delivery

by Adam C. Watkinson Heather A. Benson

Practical drug development approaches presented by leading expertsDesigned to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development.Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts:Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment.Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics.Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results.With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.

Topics in Cognitive Rehabilitation in the TBI Post-Hospital Phase

by Renato Anghinah Wellingson Paiva Linamara Rizzo Battistella Robson Amorim

Traumatic brain injury (TBI) refers to nondegenerative, noncongenital damage to the brain from an external mechanical force, which can lead to permanent or temporary impairment of cognitive, physical, and psychosocial functions, with an associated diminished or altered state of consciousness. Despite this broad definition, it is estimated that more than 1.500.000 people suffer TBI annually in US, with 20% afflicted with moderate or severe forms. Additionally, a high percentage of these patients are unable to return to their daily routine (approximately 50%). In this context, both motor and cognitive rehabilitation are extremely important for these individuals. The aim of cognitive and motor rehabilitation is to recover an individual’s ability to process, interpret and respond to environmental inputs, as well as to create strategies and procedures to compensate for lost functions that are necessary in familial, social, educational and occupational settings. The purpose of this book is to review the basic concepts related to TBI, including mechanisms of injury, acute and post-acute care, severity levels, the most common findings in mild, moderate and severe TBI survivors, and the most frequent cognitive and motor impairments following TBI, as well as to discuss the strategies used to support post-TBI patients. The most important rehabilitation techniques, both from cognitive and motor perspectives, are addressed. Finally, information regarding work and community re-entry and familial and psychological support are discussed in detail.Topics in Cognitive Rehabilitation in the TBI Post-Hospital Phase is intended as a reference guide for all professionals who have contact with or are related to patients suffering from TBI. Any professionals who work with or are related to patients suffering from TBI will find here a broad and comprehensive overview of TBI, addressing all essential issues, from acute care to rehabilitation strategies, follow up and re-socialization.

Topics in Dental Biochemistry

by Martin Levine

Over the last 20 years, biochemistry and molecular biology have undergone a revolution that has affected our understanding of the oral cavity. Topics in Dental Biochemistry is primarily designed for students of dentistry who need to relate biochemistry and molecular biology to dentally related topics in physiology, nutrition, anatomy, histology, microbiology, and immunology. The book will also be of value for dental professionals, scientists, and practitioners of medicine who are interested in hard and soft tissue structure and disease. It provides the necessary basic scientific background for a clearer understanding of bone, tooth, saliva, and surrounding soft tissue research and also for an appreciation of how dental caries and periodontal disease might be better diagnosed and controlled in the future. Dentistry was developed to treat dental caries, but since the early 20th century it has increasingly been treating periodontal, traumatic and genetic diseases affecting tooth structure and attachment. Fluoridation is discussed at length. Other methods for controlling dental caries and new or suggested methods for controlling oral hygiene and periodontal disease are also discussed.

Topics in Medical Image Processing and Computational Vision

by Renato M. Natal Jorge Joao Manuel Tavares

The sixteen chapters included in this book were written by invited experts of international recognition and address important issues in Medical Image Processing and Computational Vision, including: Object Recognition, Object Detection, Object Tracking, Pose Estimation, Facial Expression Recognition, Image Retrieval, Data Mining, Automatic Video Understanding and Management, Edges Detection, Image Segmentation, Modelling and Simulation, Medical thermography, Database Systems, Synthetic Aperture Radar and Satellite Imagery. Different applications are addressed and described throughout the book, comprising: Object Recognition and Tracking, Facial Expression Recognition, Image Database, Plant Disease Classification, Video Understanding and Management, Image Processing, Image Segmentation, Bio-structure Modelling and Simulation, Medical Imaging, Image Classification, Medical Diagnosis, Urban Areas Classification, Land Map Generation. The book brings together the current state-of-the-art in the various multi-disciplinary solutions for Medical Image Processing and Computational Vision, including research, techniques, applications and new trends contributing to the development of the related areas.

Topographic Labiaplasty: From Theory to Clinical Practice

by Pablo Gonzalez-Isaza Rafael Sánchez-Borrego

This book provides the reader a fully descriptive approach of labia minora hypertrophy and clitoral hood elongation related to anatomical variants. The expert contributors present their reproducible and structured technique of Topographic Labiaplasty, that allows the surgeon to improve surgical results and avoid complications and poor aesthetic outcomes. It also enables surgeons to understand the huge anatomical variants related to labia minora hypertrophy and clitoral frenulum complex aiming a better result from the aesthetic and functional point of view.The eighteen well written chapters include a brief historical research about the history of labiaplasty, classifications of labia minora hypertrophy, indications and contraindications for the surgery, anesthetic considerations, surgical instrumentation, reconstructive aspects, labiaplasty in teenagers and the sexological impact. The book also features surgical videos.Topographic Labiaplasty - From Theory to Practice is addressed to consultants in gynecology, plastic surgery, urogynecology and those interested in female cosmetic genital surgery.

Topographical and Pathotopographical Medical Atlas of the Chest, Abdomen, Lumbar Region, and Retroperitoneal Space

by Z. M. Seagal

Written by an experienced and well-respected physician and professor, this new volume, building on the previous volume, Ultrasonic Topographical and Pathotopographical Anatomy, and its sequel, Topographical and Pathotopographical Medical Atlas of the Head and Neck, also available from Wiley-Scrivener, presents the ultrasonic topographical and pathotopographical anatomy of the chest, abdomen, lumbar region, and retroperitoneal space, offering further detail into these important areas for use by medical professionals. This series of atlases of topographic and pathotopographic human anatomy is a fundamental and practically important book designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy. Also you can find here new theoretical and practical sections of topographic anatomy developed by the author himself which are published for the first time. They are practically important for mastering the technique of operative interventions and denying possibility of iatrogenic complications during operations. This important new volume will be valuable to physicians, junior physicians, medical residents, lecturers in medicine, and medical students alike, either as a textbook or as a reference. It is a must-have for any physician’s library.

Topographical and Pathotopographical Medical Atlas of the Human Body

by Z. M. Seagal

Written by an experienced and well-respected physician and professor, this new volume combines the entire previous four books, Ultrasonic Topographical and Pathotopographical Anatomy, and its three sequels, also available from Wiley-Scrivener, presenings the ultrasonic topographical and pathotopographical anatomy of the entire body, offering further detail into these important areas for use by medical professionals. This comprehensive and exhaustive medical atlas of topographic and pathotopographic human anatomy is a fundamental and practically important book designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy. You can also find here new theoretical and practical sections of topographic anatomy developed by the author himself which are published for the first time. They are practically important for mastering the technique of operative interventions and denying possibility of iatrogenic complications during operations. This important new volume will be valuable to physicians, junior physicians, medical residents, lecturers in medicine, and medical students alike, either as a textbook or as a reference. It is a must-have for any physician’s library.

Topographical and Pathotopographical Medical Atlas of the Pelvis, Spine, and Limbs

by Z. M. Seagal

Written by an experienced and well-respected physician and professor, this new volume, building on the previous volume, Ultrasonic Topographical and Pathotopographical Anatomy, and its sequels, also available from Wiley-Scrivener, presents the ultrasonic topographical and pathotopographical anatomy of the pelvis, spine, and limbs, offering further detail into these important areas for use by medical professionals. This series of atlases of topographic and pathotopographic human anatomy is a fundamental and practically important book designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy. Also you can find here new theoretical and practical sections of topographic anatomy developed by the author himself which are published for the first time. They are practically important for mastering the technique of operative interventions and denying possibility of iatrogenic complications during operations. This important new volume will be valuable to physicians, junior physicians, medical residents, lecturers in medicine, and medical students alike, either as a textbook or as a reference. It is a must-have for any physician’s library

Topological Data Analysis: The Abel Symposium 2018 (Abel Symposia #15)

by Markus Szymik Nils A. Baas Gunnar E. Carlsson Gereon Quick Marius Thaule

This book gathers the proceedings of the 2018 Abel Symposium, which was held in Geiranger, Norway, on June 4-8, 2018. The symposium offered an overview of the emerging field of "Topological Data Analysis". This volume presents papers on various research directions, notably including applications in neuroscience, materials science, cancer biology, and immune response. Providing an essential snapshot of the status quo, it represents a valuable asset for practitioners and those considering entering the field.

Topology and Physics of Circular DNA (CRC Press Revivals)

by Alexander Vologodskii

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

Tornado of Life: A Doctor's Journey through Constraints and Creativity in the ER

by Jay Baruch

Stories from the ER: a doctor shows how empathy, creativity, and imagination are the cornerstones of clinical care.To be an emergency room doctor is to be a professional listener to stories. Each patient presents a story; finding the heart of that story is the doctor&’s most critical task. More technology, more tests, and more data won&’t work if doctors get the story wrong. Empathy, creativity, and imagination are the cornerstones of clinical care. In Tornado of Life, ER physician Jay Baruch offers a series of short, powerful, and affecting essays that capture the stories of ER patients in all their complexity and messiness. Patients come to the ER with lives troubled by scales of misfortune that have little to do with disease or injury. ER doctors must be problem-finders before they are problem-solvers. Cheryl, for example, whose story is a chaos narrative of &“and this happened, and then that happened, and then, and then and then and then,&” tells Baruch she is "stuck in a tornado of life.&” What will help her, and and what will help Mr. K., who seems like a textbook case of post-combat PTSD but turns out not to be? Baruch describes, among other things, the emergency of loneliness (invoking Chekhov, another doctor-writer); his own (frightening) experience as a patient; the patient who demanded a hug; and emergency medicine during COVID-19. These stories often end without closure or solutions. The patients are discharged into the world. But if they&’re lucky, the doctor has listened to their stories as well as treated them.

Torres and Ehrlich Modern Dental Assisting (6th Edition)

by Doni Bird Debbie Robinson Audrey Behrens

Learn dental assisting top to bottom from the best, with the most comprehensive, most current, and most trusted text available. For more than 40 years, students and practitioners alike have relied on Modern Dental Assisting for its cutting-edge content, easy-to-grasp writing style, step-by-step procedures, engaging learning features, and top-notch visuals to master all aspects of dental assisting.

Torres and Ehrlich Modern Dental Assisting (6th Edition)

by Doni Bird Debbie Robinson Audrey Behrens

Learn dental assisting top to bottom from the best, with the most comprehensive, most current, and most trusted text available. For more than 40 years, students and practitioners alike have relied on Modern Dental Assisting for its cutting-edge content, easy-to-grasp writing style, step-by-step procedures, engaging learning features, and top-notch visuals to master all aspects of dental assisting.

Torres and Erhlich: Modern Dental Assisting, 9th Edition

by Debbie S. Robinson Doni L. Bird

User-friendly and easy to understand, Torres and Ehrlich Modern Dental Assisting, 9th Edition has everything you need to prepare for a career in dental assisting. This complete learning package includes the textbook, Evolve website, a multimedia procedures DVD with video clips and animations, and an interactive dental office CD that includes updated case studies and interactive review exercises. This book also satisfies ADA accreditation guidelines and the CDC Guidelines for Infection Control in Dental Health-Care Settings. Procedures walk you through hands-on laboratory skills and include illustrations, equipment and supplies needed, and the rationale behind each step to help you master the skills. Essential for your practice as a dental assistant, CDC boxes familiarize you with the latest CDC guidelines and illustrate how to use them in the clinical setting. Review Exercises on Evolve provide additional opportunity for reviewing the topics in the book. Shorter chapters offer a more focused discussion of each topic and help you find specific information easily. Learn the proper way to sit, reach, stretch, and position your hands and wrists in the Ergonomics chapter. Dental Caries chapter discusses the prevention and intervention of caries. Interactive Charting Exercises on the CD and written exercises in the workbook provide practice in this critical dental assisting skill. Critical Thinking questions and scenarios test your problem solving skills and provide an opportunity for classroom discussion. Patient Education boxes at the end of select chapters offer tips and strategies to help you learn to interact and share information with patients. Be aware of ethical and legal situations with Legal and Ethical Implications boxes to protect yourself and your patients. Explore the latest cutting-edge research, trends, and hot topics that relate to chapter content with Eye to the Future boxes. Student Workbook also available Multimedia Procedures DVD packaged with the text includes 60 procedural video clips with optional review questions at the end of each clip to help you visualize difficult concepts and test your knowledge. A variety of case studies and review on the Interactive Dental Office CD packaged with the text, allow you to apply your knowledge and sharpen your clinical and practice management skills. Evolve website includes Canadian content tailored to Canadas specific nutrition guidelines and privacy regulations. Electronic Resources sections list available resources for each chapter on Evolve, the CD-ROM, and the DVD to tie together the text and electronic content. Added emphasis on Expanded Functions helps you understand the skills you need to become proficient in complex procedures. Updated photos reflect the modern dental assisting environment in which you will practice practice.

Torres' Patient Care in Imaging Technology

by Andrea Dutton TerriAnn Ryan

Torres’ Patient Care in Imaging Technology, 9th Edition helps students develop the knowledge and skills they need to become safe, perceptive, and efficient radiologic technologists. The book offers a strong illustration program and a logical organization that emphasizes the connections between classroom learning and clinical practice. Fully aligned with the latest ARRT and ASRT standards, this edition covers current trends and advances in the field and offers an unparalleled array of online teaching and learning resources.

Torres' Patient Care in Imaging Technology

by TerriAnn Ryan

Now fully aligned with the latest ARRT and ASRT standards,Torres’ Patient Care in Imaging Technology, 10th Edition, by TerriAnn Ryan, helps students develop the knowledge and skills they need to become safe, perceptive, and efficient radiologic technologists. This student-focused text offers a strong illustration program and a logical organization that emphasizes the connections between classroom learning and clinical practice. Designed to keep readers informed and up to date, it covers current trends and advances in the field and offers an unparalleled array of online teaching and learning resources.

Torticollis: Differential Diagnosis, Assessment and Treatment, Surgical Management and Bracing

by Karen Karmel-Ross

Torticollis: Differential Diagnosis, Assessment and Treatment, Surgical Management and Bracing fulfills a need, long overdue. To provide pediatric physicians, orthopedists, surgeons, physical therapists, occupational therapists, and family physicians with a systematic approach to the assessment and treatment of congenital muscular torticollis, this important guidebook gives you vital information on torticollis and its impact on the growth and development of children. Underscoring the importance of early intervention, Torticollis covers the differential diagnosis of this disorder, its conservative management, the advantages of a team approach to management, the selection of appropriate treatment techniques and pathways, and the relationship between torticollis posture and development of postural control and balance.From pages packed with useful information and amply illustrated, you will learn about the various causes of torticollis, the guidelines for assessment and timing of treatment, the main goals of treatment intervention, and when surgery is necessary. Torticollis discusses the fabrication and use of custom-made neck collars to help resolve lateral head tilt and postoperative splinting. Through the book’s well-organized and clear discussions, you will also learn about: conservative management outcome surgical intervention plagiocephaly hemihypoplasia ocular torticollis evaluation guidelines motor skill development postural control and balance development assessing neck range-of-motion and strength manual therapy intervention strengthening exercises in play therapeutic handling and positioning treatment pathways exercises for posture education and midline control home intervention exercisesTorticollis teaches you how to detect torticollis early and differentiate nonmuscular torticollis etiology. You will also learn how to evaluate the entire musculoskeletal system, how to assess motor development, postural control, and balance, and how to develop an exercise treatment plan. Nowhere else will you find such a comprehensive overview of this disorder, the challenges it presents, the progress that has been made, the interventions that work, and the research that needs to be done!

Tortoise Husbandry and Welfare

by Jane Williams

Keeping captive tortoises healthy and well is a significant challenge. Because they are ectotherms, these reptiles are totally dependent upon external sources to maintain body temperature and therefore metabolic function. Their physical environment is vital for them to remain healthy, and as owners, we have to provide sufficient choice in the environment for them to be able to experience as near optimum conditions as we can. Covering all aspects of tortoise husbandry and welfare, this book advises on: - Suitable temperature ranges, light sources, humidity, substrate, space, and seasonal changes according to individual tortoise species; - Specific dietary requirements, and opportunities for expression of natural behaviours including reproduction. - Variety of environments, ranging across indoor and outdoor accommodation options, to achieve optimum conditions for tortoises in captivity Written by a leading clinical animal behaviourist, this book is an important read for anyone involved in tortoise welfare, from students and zoo rescue staff, to pet owners and the veterinarians advising them.

Tortuga: A Novel

by Rudolfo Anaya

Master storyteller Rudolfo Anaya explores the world of pain and recovery in this autobiographical novel about an injured teenage boy's journey to overcome suffering--both physical and spiritual When the story opens, the eponymous hero of Rudolfo Anaya's novel is in an ambulance en route to a hospital for crippled children in the New Mexican desert. A poor boy from Albuquerque, sixteen-year-old Tortuga takes his name from the odd, turtle-shaped mountain that is rumored to possess miraculous curative powers. Tortuga is paralyzed, and not even his mother's fervent prayers can heal him. But under the mountain's watchful gaze, with the support of fellow patients, he begins the Herculean task of breaking out of his shell and becoming whole again. Drawn from personal experience and imbued with the magic realism and phantasmagorical vision quests that distinguish Anaya's work, Tortuga is a joyful, life-sustaining book about hope, faith, friendship, and love that celebrates the triumph of the human spirit in the physical world.

Tortured by Her Touch

by Dianne Drake

The first kiss is the deepest! Ex-army doc Marc Rousseau might be devastatingly sexy, but he specializes in being difficult! No longer able to practice as a surgeon, he's working with injured war veterans alongside stunning Dr. Anne Sebastian...the one woman who sees beyond his gruff exterior. Marc knows Anne is off-limits-especially as she's unlikely to trust any man again-but being around her is such sweet torture! And when a late-night swim leads to a steamy kiss, Marc and Anne start to wonder...dare they take a chance on a future together?

Total Ankle Replacement: A Practical Guide to Surgical Management

by Beat Hintermann Roxa Ruiz

This book offers a comprehensive and up-to-date overview of ankle osteoarthritis pathologies and solutions for successful ankle replacement surgery. The opening chapters examine the anatomical basics and biomechanical features essential for understanding each pathological condition and achieving a well-balanced and stable replaced ankle. The authors further illustrate the diagnostic work-up, pre-operative planning, indications, and contraindications. Providing step-by-step guidance through the most updated surgical techniques, many of which they have pioneered themselves, they complement the path toward successful replacement surgery. Besides primary arthroplasty, the volume focuses particularly on revising failed total ankle arthroplasty and provides new insights into the possibilities and limitations of salvaging a painful ankle arthrodesis with an ankle prosthesis. A wealth of intraoperative photographs of unique quality, combined with a consistent structureand a problem-oriented approach, make this book a must-read for all foot and ankle surgeons. Moreover, it is a valuable source of information for residents wishing to gain insights into end-stage osteoarthritic ankles and for researchers and physiotherapists seeking to understand the clinician’s view on their work.

Total Diet Studies

by Gerald G. Moy Richard W. Vannoort

Unless a food is grossly contaminated, consumers are unable to detect through sight or smell the presence of low levels of toxic chemicals in their foods. Furthermore, the toxic effects of exposure to low levels of chemicals are often manifested slowly, sometimes for decades, as in the case of cancer or organ failure. As a result, safeguarding food from such hazards requires the constant monitoring of the food supply using sophisticated laboratory analysis. While the food industry bears the primary responsibility for assuring the safety of its products, the overall protection of people's diets from chemical hazards must be considered one of the most important public health functions of any government. Unfortunately, many countries do not have sufficient capability and capacity to monitor the exposure of their populations to many potentially toxic chemicals that could be present in food and drinking water. Without such monitoring, public health authorities in many countries are not able to identify and respond to problems posed by toxic chemicals, which may harm their population and undermine consumer confidence in the safety of the food supply. From a trade perspective, those countries that cannot demonstrate that the food they produce is free of potentially hazardous chemicals will be greatly disadvantaged or even subject to sanctions in the international marketplace. The goal of a total diet study (TDS) is to provide basic information on the levels and trends of exposure to chemicals in foods as consumed by the population. In other words, foods are processed and prepared as typical for a country before they are analyzed in order to better represent actual dietary intakes. Total diet studies have been used to assess the safe use of agricultural chemicals (e. g. , pesticides, antibiotics), food additives (e. g. , preservatives, sweetening agents), environmental contaminants (e. g. , lead, mercury, arsenic, cadmium, PCBs, dioxins), processing contaminants (e. g. , acrylamide, polycyclic aromatic hydrocarbons, chloropropanols), and natural contaminants (e. g. , aflatoxin, patulin, other mycotoxins) by determining whether dietary exposure to these chemicals are within acceptable limits. Total diet studies can also be applied to certain nutrients where the goal is to assure intakes are not only below safe upper limits, but also above levels deemed necessary to maintain good health. International and national organizations, such as the World Health Organization, the European Food Safety Agency and the US Food and Drug Administration recognize the TDS approach as one of the most cost-effective means of protecting consumers from chemicals in food, for providing essential information for managing food safety, including food standards, and for setting priorities for further investment and study. Total Diet Studies introduces the TDS concept to a wider audience and presents the various steps in the planning and implementation of a TDS. It illustrates how TDSs are being used to protect public health from chemicals in the food supply in many developed and developing countries. The book also examines some of the applications of TDSs to specific chemicals, including contaminants and nutrients.

Total Hip Arthroplasty

by Karl Knahr

During the 2011 EFORT Congress in Copenhagen, many interesting topics relating to tribology in total hip arthroplasty were discussed during a special day devoted entirely to the subject. EFORT decided that, given the wide interest in these discussions, publication of the presentations would be warmly welcomed by all fellow professionals who were unable to attend. This book is the result. It provides detailed information on currently used articulating materials and their wear performance. Clinical outcomes are discussed, and important new frontiers are carefully considered. The book will be of interest both to novices who want to learn more about the field and to experienced orthopaedic surgeons wishing to keep abreast of the latest developments.

Total Hip Arthroplasty: Medical and Biomedical Engineering and Science Concepts

by Emre Tokgoz

Total Hip Arthroplasty: Medical and Biomedical Engineering and Science Concepts provides an extensive overview of the most recent advancements in total hip arthroplasty (THA) through a thorough review of the literature in medicine, engineering, mathematics, computing, and related technologies. Coverage includes the most recent engineering and computing techniques such as robotics, biomechanics, artificial intelligence, and optimization, as well as the medical and surgical aspects of pre-existing conditions, surgical procedure types, postoperative complications, and patient care. This book will be a valuable introductory reference for academics, students, and researchers to THA concepts and advances.

Total Hip Arthroplasty: Tribological Considerations and Clinical Consequences

by Karl Knahr

In recent years the 'Tribology Day' has become a recognized highlight of the EFORT Congress, and at the 2012 Congress in Berlin an entire day was once again devoted to tribology in total hip arthroplasty. EFORT decided that, given the wide interest in tribology, publication of the presentations would be warmly welcomed by fellow professionals who were unable to attend. The resulting book includes all presentations delivered on the day and covers a range of interesting topics. Up-to-date information is provided on the various articulating materials, and all the articulations recently used in total hip arthroplasty are discussed, with provision of clinical data. The book will be of interest not only to experienced surgeons but also to trainees and residents who wish to extend their knowledge of total hip arthroplasty.

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