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Unser Körper - Ausdruck, Haltung, Körpersprache: Mit der TCM neu wahrnehmen

by Mike Mandl

Wer sind wir in körperlicher Hinsicht? Was sagt unser Erscheinungsbild über uns? Und was hat das alles mit chinesischer Medizin zu tun? Um diese Fragen zu beantworten, müssen wir uns nur betrachten. Unser Körper spricht zu uns. Durch seine Formen, seine Strukturen, seine Ausprägung. Er erzählt uns spannende und lehrreiche Geschichten: Über unsere Herkunft und unseren Werdegang. Über unseren Status Quo und unsere Zukunft. Er berichtet von Möglichkeiten und Grenzen, von Stärken und Schwächen, von Vorlieben und Abneigungen. Er kann uns helfen, uns selber besser kennen zu lernen. Vorausgesetzt: Wir verstehen seine Sprache. Die Sprache unseres Körpers zu erlernen, ist das Ziel dieses Buches. Der Autor vergleicht dabei Menschen mit Bäumen, spricht von Fünf Elementen, widmet sich den drei Schätzen und ist der Meinung, dass Kondition und Konstitution auf einen Nenner kommen sollen. Das wirkt auf den ersten Blick chinesisch, im zweiten Blick ist es sogar, weil eine Grundlage dieses Buches die Traditionelle Chinesische Medizin ist. Das alles wird serviert mit Leichtigkeit und einer Prise Humor: Geschichten von Kopf bis Fuß.

Unsettled: How the Purdue Pharma Bankruptcy Failed the Victims of the American Overdose Crisis

by Ryan Hampton

A shocking inside account of reckless capitalism and injustice in the Purdue Pharma bankruptcy case.In September 2019, Purdue Pharma—the maker of OxyContin and a company controlled by the infamous billionaire Sackler family—filed for bankruptcy to protect itself from 2,600 lawsuits for its role in fueling the U.S. overdose crisis. Author and activist Ryan Hampton served as co-chair of the official creditors committee that acted as a watchdog during the process, one of only four victims appointed among representatives of big insurance companies, hospitals, and pharmacies. He entered the case believing that exposing the Sacklers and mobilizing against Purdue would be enough to right the scales of justice. But he soon learned that behind closed doors, justice had plenty of other competition—and it came with a hefty price tag.Unsettled is the inside story of Purdue’s excruciating Chapter 11 bankruptcy proceedings, the company’s eventual restructuring, and the Sackler family’s evasion of any true accountability. It’s also the untold story of how a group of determined ordinary people tried to see justice done against the odds—and in the face of brutal opposition from powerful institutions and even government representatives. Although America was envisioned as an equitable place, where the vulnerable are protected from the greed of the powerful, the corporate-bankruptcy process betrays those values. In its heart of hearts, this system is built to shield the ultra-wealthy, exploit loopholes for political power, promote gross wealth inequality, and allow companies such as Purdue Pharma to run amok.The real story of the Purdue bankruptcy wasn’t that the billion-dollar corporation was a villain, a serial federal offender. No matter what the media said, Purdue didn’t do this alone. They were aided and abetted by the very systems and institutions that were supposed to protect Americans. Even on-your-side elected officials worked against Purdue’s victims—maintaining the status quo at all costs.Americans deserve to know exactly who is responsible for failing to protect people over profits—and what a human life is worth to corporations, billionaires, and lawmakers. Unsettled is what happened behind closed doors—the story of a sick, broken system that destroyed millions of lives and let the Sacklers off almost scot-free.

Unsettling Welfare: The Reconstruction of Social Policy (Social Policy: Welfare, Power and Diversity)

by Gordon Hughes Gail Lewis

Unsettling Welfare addresses the changing relationship between social welfare, its 'recipients' and the state. In particular, the book explores the direction and the impact of the reforms of the welfare state that took place during the 1980s and 1990s. By focusing on specific fields of social welfare and social control, including health, education, housing, income maintenance, social services and criminal justice, Unsettling Welfare identifies general trends and the ways in which these are manifested.

Unshrunk: A Story of Psychiatric Treatment Resistance

by Laura Delano

&“A must read for anyone probing the dark side of mental health treatment.&” —Anna Lembke, MD, New York Times bestselling author of Dopamine Nation &“A really moving and heart-rending story. Unshrunk will help and empower so many people.&” —Johann Hari, New York Times bestselling author of Stolen FocusThe powerful memoir of one woman&’s experience with psychiatric diagnoses and medications, and her journey to discover herself outside the mental health industryAt age fourteen, Laura Delano saw her first psychiatrist, who immediately diagnosed her with bipolar disorder and started her on a mood stabilizer and an antidepressant. At school, Delano was elected the class president and earned straight-As and a national squash ranking; at home, she unleashed all the rage and despair she felt, lashing out at her family and locking herself in her bedroom, obsessing over death.Delano&’s initial diagnosis marked the beginning of a life-altering saga. For the next thirteen years, she sought help from the best psychiatrists and hospitals in the country, accumulating a long list of diagnoses and a prescription cascade of nineteen drugs. After some resistance, Delano accepted her diagnosis and embraced the pharmaceutical regimen that she&’d been told was necessary to manage her incurable, lifelong disease. But her symptoms only worsened. Eventually doctors declared her condition so severe as to be &“treatment resistant.&” A disturbing series of events left her demoralized, but sparked a last glimmer of possibility. . . . What if her life was falling apart not in spite of her treatment, but because of it? After years of faithful psychiatric patienthood, Delano realized there was one thing she hadn&’t tried—leaving behind the drugs and diagnoses. This decision would mean unlearning everything the experts had told her about herself and forging into the terrifying unknown of an unmedicated life.Weaving Delano&’s medical records and doctors&’ notes with an investigation of modern psychiatry and illuminating research on the drugs she was prescribed, Unshrunk questions the dominant, rarely critiqued role that the American mental health industry, and the pharmaceutical industry in particular, plays in shaping what it means to be human.

Unshrunk: How The Mental Health Industry Took Over My Life - And My Fight to Get it Back

by Laura Delano

One of Lit Hub's Most Anticipated Books of 2025A really moving and heart-rending story. Unshrunk will help and empower so many people.JOHANN HARI, author of Stolen Focus and Lost ConnectionsUnshrunk is the story of a young woman who dared to be herself, and a potent reminder of why human suffering can never be reduced to a diagnostic manual. A must read for anyone probing the dark side of mental health treatment. ANNA LEMBKE, author of Dopamine Nation'A wonderful, incisive and deeply moving book... provides a rare glimpse behind the curtain of a profession in peril.'DR JAMES DAVIES, AUTHOR OF CRACKED AND SEDATES'Inspiring... A wake-up call about a deeply flawed system'PROFESSOR JOANNA MONCRIEFFIn this gripping, essential memoir, Laura Delano takes readers through the labyrinth of the American mental health system, where 'the best available care' left her sicker, more desperate, and more lost than ever before. This beautiful, rageful, joyful book is a beacon for all seeking a life beyond labels, beyond medication, beyond disorder.JESSICA NORDELL, AUTHOR OF THE END OF BIAS: A BEGINNING***I began to think about the forces at play, not just within me, but beyond me. What if my life hadn't fallen apart in the way that it had because of 'treatment-resistant mental illness', as I'd been led to believe, but because of the treatment itself?At age fourteen, Laura Delano's parents took her to her first psychiatrist. At school, she was the model student, but at home Laura felt an uncontrollable rage that she unleashed on family, friends and herself. She was promptly diagnosed with bipolar disorder and started on a course of mood stabilizers and antidepressants. It was to mark the beginning of a painful and relentless journey. For the next thirteen years, Laura sought help from the best psychiatrists and hospitals, accumulating an ever-expanding list of diagnoses and prescriptions for nineteen different drugs. She accepted her diagnoses and embraced the pharmaceutical regime she'd been told was necessary to manage her incurable, lifelong disease. But as her symptoms only got more severe and eventually she was deemed 'treatment resistant', Laura began to wonder if the drugs and diagnoses were the cure - or had they become the problem?Weaving together Laura's medical records and doctors' notes with illuminating research on the drugs she was prescribed, Unshrunk is the powerful memoir of one woman's battle against the commercial psychiatric industry and the role it plays in shaping what it means to be human.

Unshrunk: How The Mental Health Industry Took Over My Life - And My Fight to Get it Back

by Laura Delano

One of Lit Hub's Most Anticipated Books of 2025A really moving and heart-rending story. Unshrunk will help and empower so many people.JOHANN HARI, author of Stolen Focus and Lost ConnectionsUnshrunk is the story of a young woman who dared to be herself, and a potent reminder of why human suffering can never be reduced to a diagnostic manual. A must read for anyone probing the dark side of mental health treatment. ANNA LEMBKE, author of Dopamine Nation'A wonderful, incisive and deeply moving book... provides a rare glimpse behind the curtain of a profession in peril.'DR JAMES DAVIES, AUTHOR OF CRACKED AND SEDATES'Inspiring... A wake-up call about a deeply flawed system'PROFESSOR JOANNA MONCRIEFFIn this gripping, essential memoir, Laura Delano takes readers through the labyrinth of the American mental health system, where 'the best available care' left her sicker, more desperate, and more lost than ever before. This beautiful, rageful, joyful book is a beacon for all seeking a life beyond labels, beyond medication, beyond disorder.JESSICA NORDELL, AUTHOR OF THE END OF BIAS: A BEGINNING***I began to think about the forces at play, not just within me, but beyond me. What if my life hadn't fallen apart in the way that it had because of 'treatment-resistant mental illness', as I'd been led to believe, but because of the treatment itself?At age fourteen, Laura Delano's parents took her to her first psychiatrist. At school, she was the model student, but at home Laura felt an uncontrollable rage that she unleashed on family, friends and herself. She was promptly diagnosed with bipolar disorder and started on a course of mood stabilizers and antidepressants. It was to mark the beginning of a painful and relentless journey. For the next thirteen years, Laura sought help from the best psychiatrists and hospitals, accumulating an ever-expanding list of diagnoses and prescriptions for nineteen different drugs. She accepted her diagnoses and embraced the pharmaceutical regime she'd been told was necessary to manage her incurable, lifelong disease. But as her symptoms only got more severe and eventually she was deemed 'treatment resistant', Laura began to wonder if the drugs and diagnoses were the cure - or had they become the problem?Weaving together Laura's medical records and doctors' notes with illuminating research on the drugs she was prescribed, Unshrunk is the powerful memoir of one woman's battle against the commercial psychiatric industry and the role it plays in shaping what it means to be human.

Unsichere Operationsindikationen und Überversorgung: Häufigkeit chirurgischer und interventioneller Eingriffe im internationalen Vergleich

by Eike Sebastian Debus Reinhart T. Grundmann Viktorija Pède

Das Buch stellt mit der Analyse geographischer Unterschiede bei der Behandlung ausgewählter Erkrankungen potenzielle Einspareffekte im Gesundheitswesen dar. Dabei werden beispielhaft Eingriffe ganz verschiedener Fachgebiete (Allgemeinchirurgie, Orthopädie, Kardiologie, Hals-Nasen-Ohrenheilkunde, Urologie, Geburtshilfe) anhand nationaler und internationaler statistischer Erhebungen auf Ebene der deutschen Bundesländer und der OECD-Staaten untersucht. Auf der Basis einer Literaturrecherche in der Datenbank PubMed erfolgt die wissenschaftliche Analyse der dargestellten Unterschiede. Die Ergebnisse zeigen, dass unsichere Indikationen einen wesentlichen Grund für die Variation in der Operationshäufigkeit darstellen.

Unspeakable: Father-Daughter Incest in American History

by Lynn Sacco

First place, Large Nonprofit Publishers Illustrated Covers, 2010 Washington Book PublishersNamed one of the Top Five Books of 2009 by Anne Grant, The Providence JournalThis history of father-daughter incest in the United States explains how cultural mores and political needs distorted attitudes toward and medical knowledge of patriarchal sexual abuse at a time when the nation was committed to the familial power of white fathers and the idealized white family.For much of the nineteenth century, father-daughter incest was understood to take place among all classes, and legal and extralegal attempts to deal with it tended to be swift and severe. But public understanding changed markedly during the Progressive Era, when accusations of incest began to be directed exclusively toward immigrants, blacks, and the lower socioeconomic classes. Focusing on early twentieth-century reform movements and that era’s epidemic of child gonorrhea, Lynn Sacco argues that middle- and upper-class white males, too, molested female children in their households, even as official records of their acts declined dramatically. Sacco draws on a wealth of sources, including professional journals, medical and court records, and private and public accounts, to explain how racial politics and professional self-interest among doctors, social workers, and professionals in allied fields drove claims and evidence of incest among middle- and upper-class white families into the shadows. The new feminism of the 1970s, she finds, brought allegations of father-daughter incest back into the light, creating new societal tensions. Against several different historical backdrops—public accusations of incest against "genteel" men in the nineteenth century, the epidemic of gonorrhea among young girls in the early twentieth century, and adult women’s incest narratives in the mid-to late twentieth century—Sacco demonstrates that attitude shifts about patriarchal sexual abuse were influenced by a variety of individuals and groups seeking to protect their own interests.

Unstitched: My Journey to Understand Opioid Addiction and How People and Communities Can Heal

by Brett Ann Stanciu

What if society looked at addiction without judgement? Unstitched shares the powerful story of one librarian&’s quest to understand the impact of addiction fed by stigma and inevitable secrecy.The opioid epidemic has hit people in communities large and small and across all socio-economic classes. What should each of us know about it, and do about it? Unstitched moves readers from feelings of helplessness and blame into empathy, ultimately helping friends, family, and community members separate the disease of addiction from the person underneath.A stranger, rumored to be a heroin addict, repeatedly breaks into the small-town library Brett Ann Stanciu runs. After she tries to get law enforcement to take meaningful action against him—elementary school children and young parents with babies frequent the place after all—he dies by suicide. When she realizes how little she knows about opioid misuse, she sets out on a mission, seeking insight from others, such as people in recovery, treatment providers, the town police chief, and Vermont's US attorney. Stanciu&’s journey leads to compassionate generosity, renewed faith, and ultimately a measure of personal redemption as she realizes she has a role to play in helping the people of her community stitch themselves back together.

Unsupervised Feature Extraction Applied to Bioinformatics: A PCA Based and TD Based Approach (Unsupervised and Semi-Supervised Learning)

by Y-h. Taguchi

This updated book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tensor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics.

Untangling the Maternity Crisis: Action For Change

by Rosemary Mander Nadine Edwards Jo Murphy-Lawless

Arguing that contemporary maternity services provide a toxic environment both in which to practise and to give birth, this book looks at how we can change this. Its aim is promoting the best possible experiences of childbearing, and confident, strengthening and loving contexts for new parenthood. Designed to create awareness about the professional and political realities which enmesh maternity care, this inspiring volume features an in-depth and research-oriented analysis of the challenges faced by contemporary maternity services. Recognising the frequently hostile environment in which midwives practise, the contributors go on to explore its impact on women and families, as well as on midwives themselves. They then look at woman-centred and community-based ways of contributing to a much better birthing experience for all. Important and relevant for all those with an interest in improving maternity care, this book is particularly suited to midwives – practising and student, doulas, birth educators and activists, policymakers and health service managers.

Unternehmen Zahnarztpraxis - die Bausteine des Erfolgs

by Nicole Franzen Francesco Tafuro

Niedergelassene Zahnärzte müssen nicht nur medizinisches Geschick unter Beweis stellen, auch unternehmerische- und Führungs-Qualitäten sind gefragt. Die Autoren beschreiben den Weg zur erfolgreichen Praxis anhand von Themenblöcken: der Zahnarzt als Unternehmer-Persönlichkeit, Betriebswirtschaft, professioneller Praxisauftritt, Teamaufbau und -führung, Organisation und Zeitmanagement, Beratungs- und Aufklärungsgespräche. Fallbeispiele und Praxistipps erleichtern die Analyse der eigenen Situation. Checklisten, Formulare und Textvorlagen auf CD-ROM.

Unternehmen Zahnarztpraxis: Erfolgreich organisieren, delegieren, digitalisieren, skalieren (Erfolgskonzepte Zahnarztpraxis & Management)

by Wolfgang Schmitt Frank Zastrow

Dieses Buch erzählt von einem Zahnarzt, der die moderne Zahnarztpraxis neu gedacht hat. Begleiten Sie ihn auf seinem Weg und erfahren Sie auf unterhaltsame Weise, wie Sie die Faktoren Zeit, Geld und Leben in einen vernünftigen Einklang bringen. Entscheidend sind kluge, unternehmerische Strategien, um Freiräume zu gewinnen für das, was Ihnen wirklich wichtig ist. Wer vom Getriebenen im Hamsterrad zum Gestalter seines eigenen (Arbeits-)Lebens werden will, kommt an diesem Buch nicht vorbei. Und auch, wer nicht sofort alles anders machen möchte, findet viele nützliche Anregungen. Schaffen Sie die Basis für wirtschaftlichen Erfolg und Lebensqualität zugleich und lernen Sie:Ihre Zahnarztpraxis souverän zu führenDie eigene Expertise weiterzuentwickelnFreiraum für Außerberufliches zu schaffenRegenerationsphasen zu nutzenOrganisierenInterne Prozessoptimierung und klare VerantwortungsbereicheQualitätsmanagement als ChanceModerne maßgeschneiderte Inhouse-KommunikationssystemeDelegierenWas gebe ich wie an wen?Das optimale PraxisteamErfolgsfaktor WertschätzungDigitalisierenPatientengewinnung und -bindung online/offlineWas bieten Sie, was andere nicht haben?Empfehlungs-Marketing und Online-BewertungenSkalierenWelche Praxisform passt zu Ihnen?Einzelpraxis, Gemeinschaftspraxis oder MVZ?Rechtliche und wirtschaftliche Unterschiede

Unterrichten und Präsentieren in Gesundheitsfachberufen

by Jörg Schmal

Souverän und anschaulich unterrichten!Dieses Buch richtet sich an Dozenten und Lehrende in Gesundheitsfachberufen und bietet umfangreichen Inhalt für eine gute Gestaltung von Vorträgen, praktischen und theoretischen Unterrichtseinheiten oder Präsentationen. Ein Fachgebiet zu kennen, heißt nicht, es auch ansprechend präsentieren zu können. Der erfahrene Autor hilft Ihnen zu verstehen, was guten Unterrichtet ausmacht und wie Sie Ihre Inhalte erfolgreich weitergeben können. Anhand zahlreicher Praxisbeispiele stellt er didaktische und methodische Grundlagen leicht verständlich und umsetzbar dar. Dabei werden über 60 verschiedene Methoden für abwechslungsreiche Lehr-Lerneinheiten aufgezeigt.So werden Sie sicher in der Darbietung und kreativ in der Wissensvermittlung!

Unterrichten und Präsentieren in Gesundheitsfachberufen: Methodik und Didaktik für Praktiker

by Jörg Schmal

Zeitgemäß und anschaulich unterrichten! Dieses Buch richtet sich an Dozenten und Lehrende in Gesundheitsfachberufen und bietet umfangreichen Inhalt für eine gute Gestaltung von Vorträgen, praktischen und theoretischen Unterrichtseinheiten oder Präsentationen. Ein Fachgebiet zu kennen, heißt nicht, es auch ansprechend präsentieren zu können. Der erfahrene Autor hilft Ihnen zu verstehen, was guten Unterricht ausmacht und wie Sie Ihre Inhalte erfolgreich weitergeben können. Anhand zahlreicher Praxisbeispiele stellt er didaktische und methodische Grundlagen leicht verständlich und umsetzbar dar. Dabei werden über 60 verschiedene Methoden für abwechslungsreiche Lehr-Lerneinheiten aufgezeigt. So bleibt Ihr Unterricht aktuell und spannend!

Untersuchen und Befunden in der Physiotherapie: Untersuchungstechniken und Diagnoseinstrumente (Physiotherapie Basics)

by Kay Bartrow

Dieses praxisorientierte Lehrbuch vermittelt Schülern und Studierenden der Physiotherapie und Berufseinsteigern das essentielle Handwerkszeug für die physiotherapeutische Untersuchung als Grundlage für eine erfolgversprechende Therapie. Praktisches Vorgehen, Untersuchungs- und Testverfahren, Befundinterpretation, Dokumentation, sowie kompaktes Hintergrundwissen werden strukturiert und verständlich erläutert. Für jeden Untersuchungsschritt wird das Vorgehen anhand ausführlicher Patientenbeispiele und mit zahlreichen Abbildungen veranschaulicht. Plus: Zusatzmaterialien zum Download Neu in der 3. Auflage: typische Fallbeispiele zur Veranschaulichung des Clinical Reasoning Prozesses, erweiterte Hinweise zur Dokumentation von Befundergebnissen, zusätzliche Informationen zum Flaggensystem in der Physiotherapie Für Ausbildung, Studium, Berufsstart und für erfahrene Therapeuten, die ihr Praxiswissen auffrischen wollen.

Untersuchung von linearen und zirkulären Transkripten des TRAM1- und S100A6-Genlokus im Kontext des Harnblasenkarzinoms

by Josephine Dubois

Das Harnblasenkarzinom gehört weltweit zu den häufigsten Krebserkrankungen und wird meist erst im Endstadium erkannt. Gegenwärtig verwendete diagnostische Verfahren sind invasiv, zeit- und kostenintensiv und verbunden mit dem Risiko weiterer Komplikationen. Die Entwicklung von nicht-invasiven Tumormarkern für die Diagnose und Nachsorge von Harnblasenkarzinomen ist von großem klinischen Interesse und könnte anhand von RNA-Markern im Patientenurin realisiert werden. Im ersten Schritt wurde daher das Transkriptom vom Urin gesunder Patienten mit dem von Harnblasenkarzinom-Patienten im fortgeschrittenen Tumorstadium verglichen und potentielle Tumormarker identifiziert. Anschließend wurde der Fokus auf die Analyse von linearen und zirkulären RNA-Spezies des TRAM1- und S100A6-Genlokus gelegt und umfassende Studien zur Detektion und Verifizierung der Transkripte durchgeführt. Dabei empfahlen sich insbesondere S100A6-RNAs durch eine solide Nachweisbarkeit im Patientenurin und eine erhöhte Expression mit fortschreitendem Krankheitsstadium als Tumormarker für das Harnblasenkarzinom. Zirkuläre RNAs standen aufgrund ihrer vermuteten erhöhten Stabilität in Körperflüssigkeiten und der bereits bekannten Tumor-biologischen Funktionen ebenfalls im Mittelpunkt der Untersuchungen. Ein besseres Verständnis der vielfältigen Funktionen von zirkulären Transkripten könnte zudem die Entwicklung von therapeutischen Strategien zur Behandlung von Blasentumoren vorantreiben.

Unthinkable: An Extraordinary Journey Through the World's Strangest Brains

by Helen Thomson

'Wonderfully clear, fluent and eye-opening' THE TIMES'A stirring scientific journey, a celebration of human diversity and a call to rethink the "unthinkable"' NATURE'An utterly fascinating romp around the nether regions of the human mind' BIG ISSUEIMAGINE . . . getting lost in a one-room flat; seeing auras; never forgetting a moment; a permanent orchestra in your head; turning into a tiger; life as an out-of-body experience; feeling other people's pain; being convinced you are dead; becoming a different person overnight.Our brains are far stranger than we think. We take it for granted that we can remember, feel emotion, navigate, empathise and understand the world around us, but how would our lives change if these abilities were dramatically enhanced - or disappeared overnight? Award-winning science writer Helen Thomson has spent years travelling the world tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways. Delving into the rich histories of these conditions, exploring the very latest research and cutting-edge medical techniques, Thomson explains the workings of our consciousness, our emotions, our creativity and even the mechanisms that allow us to understand our own existence. Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

Unthinkable: An Extraordinary Journey Through the World's Strangest Brains

by Helen Thomson

How the mind works -- everything from memory to emotion, navigation to creativity -- explained in nine extraordinary human stories.IMAGINE . . . getting lost in a one-room flat; seeing auras; never forgetting a moment; a permanent orchestra in your head; turning into a tiger; life as an out-of-body experience; feeling other people's pain; being convinced you are dead; becoming a different person overnight.Our brains are far stranger than we think. We take it for granted that we can remember, feel emotion, navigate, empathise and understand the world around us, but how would our lives change if these abilities were dramatically enhanced - or disappeared overnight? Award-winning science writer Helen Thomson has spent years travelling the world tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways. Delving into the rich histories of these conditions, exploring the very latest research and cutting-edge medical techniques, Thomson explains the workings of our consciousness, our emotions, our creativity and even the mechanisms that allow us to understand our own existence. Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.(P)2018 John Murray Press

Unthinkable: An Extraordinary Journey Through the World's Strangest Brains

by Helen Thomson

In this Indiebound bestseller, the award-winning science writer unlocks the biggest mysteries of the human brain by examining nine extraordinary cases.Our brains are far stranger than we think. We take it for granted that we can remember, feel emotion, navigate, empathize and understand the world around us, but how would our lives change if these abilities were dramatically enhanced—or disappeared overnight?Helen Thomson has spent years travelling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he’s a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.“Helen Thomson’s remarkable book is an astonishing tour of the human brain in all its awesome power and bewildering variation . . . Unthinkable will enrich your brain, blow your mind, and warm your heart.” —Ed Yong, Pulitzer Prize-winning author

Until Further Notice, I Am Alive

by Tom Lubbock

&“These are thoughts for us all, sooner or later—and this is a book I'll keep with me, as long as I live.&”—David Sexton, The Scotsman In 2008, art critic Tom Lubbock was diagnosed with a rare brain tumor and told he had only two years to live. Physically fit and healthy, and suffering from few symptoms, he faced his death with the same directness and courage that had marked the rest of his life. Lubbock was renowned for the clarity and unconventionality of his writing, and his characteristic fierce intelligence permeates this extraordinary chronicle. With unflinching honesty and curiosity, he repeatedly turns over the fact of his mortality, as he wrestles with the paradoxical question of how to live, knowing we&’re going to die. Defying the initial diagnosis, Tom survived for three years. He savored his remaining days; engaging with books, art, friends, his wife and their young son, while trying to stay focused on the fact of his impending death. There are medical details—he vividly describes the slow process of losing control over speech as the tumor gradually pressed down on the area of his brain responsible for language—but this is much more than a book about illness; rather, it's a book about a man who remains in thrall to life, as he inches closer to death. &“I hope that if I am ever diagnosed with a terminal illness I will remember to reread Until Further Notice, I Am Alive. It is, in its tough-minded way, truly joyous.&”—Lynn Barber, Sunday Times

Until Proven Safe: The History and Future of Quarantine, from the Black Death to the Space Age

by Geoff Manaugh Nicola Twilley

Geoff Manaugh and Nicola Twilley have been researching quarantine since long before the COVID-19 pandemic. With Until Proven Safe, they bring us a book as compelling as it is definitive, not only urgent reading for social-distanced times but also an up-to-the-minute investigation of the interplay of forces–––biological, political, technological––that shape our modern world.Quarantine is our most powerful response to uncertainty: it means waiting to see if something hidden inside us will be revealed. It is also one of our most dangerous, operating through an assumption of guilt. In quarantine, we are considered infectious until proven safe.Until Proven Safe tracks the history and future of quarantine around the globe, chasing the story of emergency isolation through time and space—from the crumbling lazarettos of the Mediterranean, built to contain the Black Death, to an experimental Ebola unit in London, and from the hallways of the CDC to closed-door simulations where pharmaceutical execs and epidemiologists prepare for the outbreak of a novel coronavirus.But the story of quarantine ranges far beyond the history of medical isolation. In Until Proven Safe, the authors tour a nuclear-waste isolation facility beneath the New Mexican desert, see plants stricken with a disease that threatens the world’s wheat supply, and meet NASA’s Planetary Protection Officer, tasked with saving Earth from extraterrestrial infections. They also introduce us to the corporate tech giants hoping to revolutionize quarantine through surveillance and algorithmic prediction.We live in a disorienting historical moment that can feel both unprecedented and inevitable; Until Proven Safe helps us make sense of our new reality through a thrillingly reported, thought-provoking exploration of the meaning of freedom, governance, and mutual responsibility.

Until We're Seen: Public College Students Expose the Hidden Inequalities of the COVID-19 Pandemic (Contemporary Ethnography)

by Joseph Entin and Jeanne Theoharis with Dominick Braswell

Firsthand accounts of COVID-19’s devastating effects on working-class communities of colorThe first months of the COVID-19 pandemic were filled with talk of heroes, the frontline workers who kept the country functioning. “And when they write those history books, the heroes of the battle will be the hardworking families of New York,” Governor Andrew Cuomo trumpeted on Labor Day 2020. But what if those heroes, those essential workers and their families, wrote the book themselves?In Until We’re Seen, the heroes write their own stories. Through firsthand accounts by college students at Brooklyn College and California State University Los Angeles, Until We’re Seen chronicles COVID-19’s devastating, disproportionate effects on working-class communities of color, even as the United States has declared the pandemic over and looks away from its impacts.Very few of these students and their families had the luxury of laboring from home; if they were able to keep their jobs, they took subways and buses, and they worked. They drove delivery trucks, worked in private homes, cooked food in restaurants for people to pick up, worked as EMTs, and did construction. They couldn’t escape to second homes; if anything, more people moved in, as families were forced to consolidate to save money. Together, the accounts in this book show that the COVID-19 pandemic did discriminate, following the race and class fissures endemic to US society. But if these are tales of hardship, they are also love stories—of students’ families, biological and chosen—and of the deep resolve, mundane carework, and herculean efforts such love entails.Recounting 2020–2022 through the experiences of predominantly young, working-class immigrants and people of color living in the first two major US COVID-19 epicenters, Until We’re Seen spotlights previously untold stories of the pandemic in New York, Los Angeles, and the nation as a whole.

Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression

by Lucy W. Barrett Sue Fletcher Steve D. Wilton

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.

Unusual Cases in Peritoneal Surface Malignancies

by Emel Canbay

This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies which have originated from different primaries, such as breast cancer, small bowel cancers and imatinib resistant GISTosis and sarcomas and pseudomyxoma. The book provides the most up-to-date information on current approaches such as cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Given the increasing evidence that the patients who may benefit from this treatment modality avoid potential lethal course of these diseases, the book explores the application of these approaches to a number of types of malignancy. The first chapters explore Benign Multicystic Mesothelioma and Pseudomyxoma Peritonei arising from unusual primaries. Among other explored topics are peritoneal metastases from serous papillary uterine carcinoma, sarcoma and from unusual origins. This book is valuable for surgical oncologists who deal with the management of peritoneal surface malignancies.

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