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Using R for Biostatistics
by Jan M. Yates Thomas W. MacFarlandThis book introduces the open source R software language that can be implemented in biostatistics for data organization, statistical analysis, and graphical presentation. In the years since the authors’ 2014 work Introduction to Data Analysis and Graphical Presentation in Biostatistics with R, the R user community has grown exponentially and the R language has increased in maturity and functionality. This updated volume expands upon skill-sets useful for students and practitioners in the biological sciences by describing how to work with data in an efficient manner, how to engage in meaningful statistical analyses from multiple perspectives, and how to generate high-quality graphics for professional publication of their research. A common theme for research in the diverse biological sciences is that decision-making depends on the empirical use of data. Beginning with a focus on data from a parametric perspective, the authors address topics such as Student t-Tests for independent samples and matched pairs; oneway and twoway analyses of variance; and correlation and linear regression. The authors also demonstrate the importance of a nonparametric perspective for quality assurance through chapters on the Mann-Whitney U Test, Wilcoxon Matched-Pairs Signed-Ranks test, Kruskal-Wallis H-Test for Oneway Analysis of Variance, and the Friedman Twoway Analysis of Variance. To address the element of data presentation, the book also provides an extensive review of the many graphical functions available with R. There are now perhaps more than 15,000 external packages available to the R community. The authors place special emphasis on graphics using the lattice package and the ggplot2 package, as well as less common, but equally useful, figures such as bean plots, strip charts, and violin plots. A robust package of supplementary material, as well as an introduction of the development of both R and the discipline of biostatistics, makes this ideal for novice learners as well as more experienced practitioners.
Using Statistics in the Social and Health Sciences with SPSS and Excel
by Martin Lee AbbottProvides a step-by-step approach to statistical procedures to analyze data and conduct research, with detailed sections in each chapter explaining SPSS® and Excel® applications This book identifies connections between statistical applications and research design using cases, examples, and discussion of specific topics from the social and health sciences. Researched and class-tested to ensure an accessible presentation, the book combines clear, step-by-step explanations for both the novice and professional alike to understand the fundamental statistical practices for organizing, analyzing, and drawing conclusions from research data in their field. The book begins with an introduction to descriptive and inferential statistics and then acquaints readers with important features of statistical applications (SPSS and Excel) that support statistical analysis and decision making. Subsequent chapters treat the procedures commonly employed when working with data across various fields of social science research. Individual chapters are devoted to specific statistical procedures, each ending with lab application exercises that pose research questions, examine the questions through their application in SPSS and Excel, and conclude with a brief research report that outlines key findings drawn from the results. Real-world examples and data from social and health sciences research are used throughout the book, allowing readers to reinforce their comprehension of the material. Using Statistics in the Social and Health Sciences with SPSS® and Excel® includes: * Use of straightforward procedures and examples that help students focus on understanding of analysis and interpretation of findings * Inclusion of a data lab section in each chapter that provides relevant, clear examples * Introduction to advanced statistical procedures in chapter sections (e.g., regression diagnostics) and separate chapters (e.g., multiple linear regression) for greater relevance to real-world research needs Emphasizing applied statistical analyses, this book can serve as the primary text in undergraduate and graduate university courses within departments of sociology, psychology, urban studies, health sciences, and public health, as well as other related departments. It will also be useful to statistics practitioners through extended sections using SPSS® and Excel® for analyzing data. Martin Lee Abbott, PhD, is Professor of Sociology at Seattle Pacific University, where he has served as Executive Director of the Washington School Research Center, an independent research and data analysis center funded by the Bill & Melinda Gates Foundation. Dr. Abbott has held positions in both academia and industry, focusing his consulting and teaching in the areas of statistical procedures, program evaluation, applied sociology, and research methods. He is the author of Understanding Educational Statistics Using Microsoft Excel® and SPSS®, The Program Evaluation Prism: Using Statistical Methods to Discover Patterns, and Understanding and Applying Research Design, also from Wiley.
Using Story Telling as a Therapeutic Tool with Children (Helping Children with Feelings)
by Margot SunderlandThis practical handbook begins with the philosophy and psychology underpinning the therapeutic value of story telling. It shows how to use story telling as a therapeutic tool with children and how to make an effective response when a child tells a story to you. It is an essential accompaniment to the "Helping Children with Feelings" series and covers issues such as: Why story telling is such a good way of helping children with their feelings? What resources you may need in a story-telling session? How to construct your own therapeutic story for a child? What to do when children tell stories to you? Things to do and say when working with a child's story.
Using Technology in Human Services Education: Going the Distance
by Goutham Menon Nancy K. BrownMake the most of what today&’s technology has to offer in human services education!Distance education presents special challenges to social work education. Using Technology in Human Services Education: Going the Distance provides case studies and practical research on making the best use of this powerful new tool for teaching. Designed for both practitioners and educators, this fascinating book examines the use of technology in education and practice in the field of social work and other human services. Because setting up distance-learning programs can be expensive, Using Technology in Human Services Education suggests ways to reduce the impact on the budget, including setting up a consortium to merge resources with other schools. It also shows how to integrate traditional instructional approaches with the new technologies, how to make use of email and electronic discussion groups, and how to use the Internet to hone practice-related skills. In addition, it covers the current status of the technology itself.Using Technology in Human Services Education: Going the Distance explores ways to maximize the potential of distance education, such as: a framework for designing distance education courses that fully utilize the unique environments these courses offer a discussion of the impact of technological tools in teaching specific course content ways that SACs (Site Advisory Committees) can increase students&’ socialization into their new professions ways that students need to be supported in order to feel a connection to a distance-learning program the use of GIS (Geographic Information Systems) to help meet and identify the information needs of a field placement agencyUsing Technology in Human Services Education offers creative approaches and practical advice for making the best use of the technology. Whatever your level of computer skill, from novice to hacker, this book will give you ideas you can use. No individual or institution interested in maintaining top quality in human services education should be without this book!
Using the Bowen Technique to Address Complex and Common Conditions
by Isobel Knight John WilksThe Bowen technique resets and repairs the body, restoring balance to relieve pain and improve energy. This book shows how it can be particularly effective at alleviating conditions that are renowned for being difficult to treat, as well as at enhancing performance in dance and other sports. Covering lower back pain, frozen shoulder, tennis elbow, carpal tunnel, hayfever, asthma, diabetes (type 2), migraines, stress and tension disorders, fibromyalgia, chronic fatigue, palliative care, performance enhancement, and in pre and post-natal care, clinical case studies reveal Bowen technique in action along with detailed explanations of how and why Bowen is so effective for each of these different situations. This is the perfect book for Bowen practitioners, and other complementary and alternative health practitioners and medical professionals wanting to know how and why the Bowen technique can help their patients, as well as patients interested in learning about what Bowen can do for them.
Using the Delphi Method to Establish Expert Consensus: A Practical Guide (Advancing Methods for Interdisciplinarity in the Social Sciences)
by Anthony JormThis Open Access book provides detailed practical guidance on how to do a Delphi study to establish a consensus across the broad range of social, psychological, health and environmental sciences. The book informs the design of Delphi studies by drawing on wisdom-of-crowds research on the conditions under which groups make better-quality judgements. It covers the development of the Delphi method and its many variations, as well as the ways this method has been used to make judgements of facts where the evidence is imperfect, set methodological standards, make predictions, define foundational concepts, determine collective values, and improve professional practice and policy. It takes the reader through the steps in carrying out a Delphi study and the choices that have to be made at each step. It also covers the implementation of Delphi findings in practice. Case examples are included throughout drawing from a variety of disciplines.
Using the Pharmaceutical Literature
by Sharon SrodinGathering information of critical importance for professionals in the pharmaceutical and medical device industries, this guide provides a comprehensive overview of key resources, such as databases, on-line directories, reports, and periodicals-providing at-a-glance guidance and collection development tools for information professionals in this fiel
Uterine Adenomyosis
by Marwan Habiba Giuseppe BenagianoRecent advances in imaging have renewed interest in uterine adenomyosis. The disease can now be diagnosed before hysterectomy which has advanced our understanding of its clinical impact, such as its effect on fertility. This book will provide an in-depth reference to recent scientific advances in the pathophysiology of uterine adenomyosis. It will represent some of the most up-to date and authoritative work in the field. This book is aimed at specialist clinicians and postgraduates wishing to acquire in-depth understanding of adenomyosis, and will be an essential reading for research scientists who will find a distillation of an up-to-date critical reading of literature.
Uterine Cancer
by Shalini Rajaram K. Chitrathara Amita MaheshwariUterine cancers are the commonest malignancies of the female genital tract in the developed world, and are increasing in numbers world over because of obesity and other life-style changes. Many of these malignancies are hereditary and thus, a better understanding of the genetic and molecular biology is needed. This would lead to appropriate treatment plan for improving the quality of life and long-term survival. This book addresses, in depth, all aspects of uterine malignancies covering both carcinomas and sarcomas. The book is divided into seven sections; the first two sections deal with epidemiology, molecular aspects, familial cancers and pathology and the later sections focus on diagnosis, imaging techniques and comprehensive management of both early stage and advanced cancers. Surgical techniques, adjuvant chemotherapy and radiotherapy have been covered in detail. Apart from the open surgical methods, role of laparoscopy and emerging role of robotic surgery in the contemporary management of endometrial cancers have been discussed. Written by authors with expertise in the field of gynecologic oncology from premier institutes, this book provides up-to-date information on best practice management of uterine malignancies.
Uterine Cancer
by David M. Luesley Andrew Berchuck Frank G. LawtonThis authoritative reference compiles the latest studies on the epidemiology, diagnosis, and treatment of uterine cancer and offers an extensive review of the molecular pathogenesis of endometrial and uterine disorders-analyzing patterns of disease presentation as population demographics change and considering the challenges this will place on future healthcare procedures.
Uterine Cancer
by Franco Muggia Esther OlivaThere are an estimated 41,000 new cases of Uterine and Endometrial Cancer each year in the United States alone, resulting in roughly 7300 deaths. In Uterine Cancer: Screening, Diagnosis and Treatment, Franco Muggia, Esther Oliva and a panel of prominent medical and gynecologic oncologists survey all aspects of Uterine and Endometrial Cancer, including current screening methods, staging and prognostic factors, and available treatment options. The discussion includes the role of imaging in the diagnosis and treatment of endometrial cancer, the molecular pathology and genetics of uterine cancer and the essential epidemiology of cancer of the endometrium. Authoritative and highly practical, Uterine Cancer: Screening, Diagnosis and Treatment is the definitive text on the most common cancer of the female genital tract, and a must-have for all gynecological residents and fellows, as well as gynecological oncologists and family practice doctors who wish to provide their patients with the best possible care.
Uterine Cancer: Screening, Diagnosis, and Treatment (Current Clinical Oncology)
by Franco Muggia Esther Oliva Alessandro D. SantinThere are more than 63,000 new cases of uterine and endometrial cancer each year in the United States, up from approximately 41,000 when the first edition of Uterine Cancer was published in 2009. A book focusing on these cancers was timely, with emergent sophistication in diagnosis increasingly impacting clinical decision-making. However, five years later, the need for an updated book on this topic is even stronger as oncologists recognize opportunities to impact the outcome on women that are increasingly diagnosed with these malignancies. Uterine Cancer: Screening, Diagnosis, and Treatment, Second Edition, part of the Current Clinical Oncology series, enhances the awareness on this somewhat neglected area of therapeutics, helping to integrate targeted therapies into the management of women with uterine cancer. Written by experts in the field in a highly practical and comprehensive manner, it is a must-have for all gynecological residents and fellows, as well as gynecological oncologists, medical oncologists, radiation oncologists, and family practice doctors who wish to provide their patients with the best possible care.
Uterine Cervical Cancer: Clinical and Therapeutic Perspectives
by Samir A. FarghalyThis volume provides a broad background of the basic sciences, clinical and therapeutic aspects, and management of uterine cervical cancer. It offers state-of-the-art information on the molecular genetics, biology, and clinical aspects of premalignant lesions of the uterine cervix, and provides a better understanding of the molecular and cellular events that underlie uterine cervical cancer. Uterine Cervical Cancer: Clinical and Therapeutic Perspectives contains extensive, updated information on the promising new developments in the diagnosis and management of uterine cervical cancer. It will serve as an invaluable resource for all clinicians and basic medical scientists caring for women with uterine cervical cancer, including attending surgeons, physicians, clinical fellows, and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology.
Uterine Endometrial Function
by Hideharu KanzakiThis book focuses on uterine endometrial function and receptivity from multiple perspectives. The chapters cover a variety of topics including the role of estrogen and progesterone, animal models, parameters for assessing endometrial receptivity, the mechanism of angiogenesis, epigenetic regulation, and stem/progenitor cells. Despite nearly 35 years of experience with in vitro fertilization, the rate of successful implantations remains low. Abnormal endometrial receptivity has been proposed as one of the factors contributing to reduced reproductive potential in women, but our understanding of it is limited. Endometrial receptivity results from an orchestrated interplay between the embryo and the maternal endometrium, and the receptive status, known as the window of implantation, is reached only briefly in the mid-luteal phase. This book provides a comprehensive overview of the latest advances in endometrial function and paves the way for innovative treatments and drug development for infertility. This work will appeal to a wide readership, from researchers on endometrial function and assisted reproductive technology (ART) to clinicians and technicians in the field of gynecology.
Uterine Fibroids
by John C. PetrozzaUterine fibroids are a painful condition that may also create serious limitations on a patient's reproductive options. This new text from an acknowledged expert at a major regional referral center fully reviews the relevant diagnostic factors as well as the potential new medical treatments and current thinking about the various - sometimes controversial - surgical options available for management. Print versions of this book also include access to the eBook version with links to procedural videos.
Uterine Fibroids and Adenomyosis (Comprehensive Gynecology and Obstetrics)
by Norihiro SuginoThis volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understanding of the pathogenesis and pathophysiology of these benign tumors. Renowned experts provide detailed discussions of basic research and clinical aspects of uterine fibroids and adenomyosis in this book, from histopathology and molecular pathogenesis to diagnosis and the latest treatment of uterine fibroids, including pregnancy complications of adenomyosis. A great deal of information and a deep understanding of molecular and genetic biology have led to development of more innovative treatments of these tumors. Thus this book benefits not only oncologists, seasoned gynecologists, and obstetricians, but also molecular biologists and other basic researchers who are involved in the treatment of uterine fibroids.
Uterine Fibroids: The Complete Guide (A Johns Hopkins Press Health Book)
by Elizabeth A. StewartProviding the most reliable and up-to-date information on this very common and difficult disorder, Dr. Stewart helps women understand uterine fibroids and make the best possible choices about their care.You've called in sick today. Your back and legs hurt. Your abdomen is bloated and more than a little uncomfortable. You are having your period, and the bleeding is so heavy you can't even think about leaving the house. You have uterine fibroids.One in every four women see their lives affected by uterine fibroids, which can cause heavy bleeding, abdominal bloating, pain, and infertility. The symptoms can be mildly annoying or life altering in severity. Until recently, hysterectomy was the only way to cure fibroids, and each year more than 200,000 hysterectomies are performed in the United States to treat these noncancerous growths. But hysterectomy isn’t always the best solution. The procedure can be devastating for women who were planning to get pregnant, and it is a significant surgery for anyone. In this comprehensive and compassionate guide, Dr. Elizabeth A. Stewart helps women understand the treatment options now available.An internationally recognized expert on fibroids, Dr. Stewart describes all the available medical and surgical treatments as well as alternative and complementary therapies. In addition to hysterectomy, she explains uterine artery embolization (UAE), noninvasive focused ultrasound (FUS), and innovative hormone treatments. Simple diagrams and photographs illustrate the condition—and its treatment. Dr. Stewart encourages women with fibroids to learn as much as they can before choosing a treatment plan. Providing the most reliable and up-to-date information on this very common and difficult disorder, she helps women understand uterine fibroids and make the best possible choices about their care.
Uterine Myoma, Myomectomy and Minimally Invasive Treatments
by Andrea Tinelli Antonio MalvasiUterine myomas are the most common benign tumors in women, affecting the half of women and mostly in reproductive age. Myomas cause significant morbidity and are the single most common indication for hysterectomy around the world. Thus, myomas represent a major personal and public health concern worldwide. The diagnosis of fibroids can be established based on ultrasound and radiological imaging. Recent research on the genomics and molecular biology of myomas has enabled us to better understand the pathogenesis and pathophysiology of this benign tumor, but more remains to be discovered. In the clinical parterre, novel methods of conservative treatments have been developed to allow many women to keep their reproductive capacity and to save uterus, and more novel treatments are available on the horizon. For this topic, an outstanding group of worldwide experts have come together to provide a detailed discussion of basic research and clinical aspects of myomas. All the existing knowledge will be summarized in this book that can serve as a starting point for clinicians, young doctors, students, fellows and all researchers who want to read up on this disease. This book is devoted to myomas, covering both recent advances in our understanding of their behaviour, and an overview of the current options for their minimally invasive treatments, with endoscopy and new devices. As we learn more about the molecular, genetic and biology of myomas, we will be able to develop more innovative treatments.
Uterine Pathology
by Robert A. Soslow Teri A. LongacrePart of the Cambridge Illustrated Surgical Pathology series, this book provides a comprehensive account of the experienced gynecologic pathologists' diagnostic approach to uterine pathology. Discussion is built around major pathologic entities in the uterus and cervix while highlighting the diverse and complex spectrum of alterations encountered in daily practice. Emphasizing clear description, diagnostic algorithms and problem solving, the book's primary goal is to lay the foundation for diagnostic accuracy, reproducibility, and relevance. It also dispels common misconceptions and encourages an intelligent and thoughtful approach to diagnostic problems using all the tools available to the modern physician. The book is richly illustrated, with more than 700 color photomicrographs, all of which are also found in downloadable format on the accompanying CD-ROM.
Uterus Transplantation
by Mats BrännströmThis book discusses all aspects of the uterus transplantation procedure in women who are childless because of a dysfunctional or missing uterus, from initial pre-operative investigations to follow-up after the uterine graft has been removed. All the international experts who are engaged in clinical activities and/or research in this field have contributed one or more of the book’s chapters. Since the first live birth following uterus transplantation was reported in Sweden in September 2014, the field has been rapidly evolving around the globe: the first cases in USA, Germany, China, Brazil, and Czech Republic were performed in 2016 and several other centres are preparing for clinical trials of uterus transplantation. Uterus transplantation is a subject that attracts the attention of many bioethicists, and like all other major procedures in transplantation surgery and assisted reproduction techniques, it is a complex process that requires a multidisciplinary team if it is to be successful. As such the book is a valuable resource not only for clinicians from many disciplines, but also for nurses, ethicists, psychologists and researchers.
Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies
by Afshin Amini Samar Masoumi-Moghaddam David L. MorrisThis volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer. It will coherently review the pathophysiological aspects of the mucin glycoproteins in malignancies and provide an updated account of the status of bromelain and N-acetylcysteine in cancer therapy. The volume will develop the idea of using these two drugs as a combination formulation for mucin-depleting effects.
Utilizing Effective Risk Communication in COVID-19: Highlighting the BRCT
by Erik Rifkin Andy LazrisThis book demonstrates how a novel decision-aid, called a Benefit-Risk Characterization Theater (BRCT), can be used to:· Significantly improve accurate communication of health risks from exposure to COVID-19; and· Assess how to best contain and control COVID-19.To date, there have been far-reaching ramifications based on ineffective risk communication when clarifying these health endpoints.A BRCT is a familiar, theatrical chart representation of 1,000 people, with the risks and benefits shown by blackened seats. Since health outcomes can easily be put into such a chart, we show how BRCTs can be used objectively by professionals, the media and lay people. It allows characterization and communication of health benefits and risks of COVID-19 treatment and containment in an undemanding and straightforward way.BRCTs have been successfully used to assist patients in determining:· Their level of acceptable risk of various medical interventions;· If the benefits of intervention outweigh the risks;· Who should make the final decision regarding medical intervention; and· Whether the decision is evidence-based.Written by experts in the field, this book fills in a gap in communication between the medical community, the public and patients. It also provides an area of expertise in communication that is beneficial for medical providers and medical students.
Utilizing the 3Ms of Process Improvement in Healthcare: A Roadmap to High Reliability Using Lean, Six Sigma, and Change Leadership
by Richard MorrowUtilizing the 3Ms of Process Improvement in Healthcare supplies step-by-step guidance on how to use the 3Ms of change leadership to improve healthcare processes. Complete with forms, templates, and healthcare case studies, it illustrates the proper application of the 3Ms. It weaves stories throughout the book of role models who have succeeded, as w
Uveal Melanoma: Biology and Management
by Eric H. BernickerThis book provides a comprehensive examination of uveal melanoma, a rare neoplasm that carries a very high mortality and whose natural history makes it fairly unique among adult tumors. Split into three sections, this book explores the basic science behind the disease and inherited genetic syndromes that predispose some patients, as well as the pathology and use of gene expression profiling to determine risk of recurrence. It also focuses on the management of the primary tumor in the eye, including surgical intervention and lesion imaging. Elucidating treatment options for metastatic disease, the book reviews chemotherapy agents and immunotherapy approaches, as well as liver-directed therapies, cellular therapies, and various treatments after primary treatment but before the development of metastases.Uveal Melanoma: Biology and Management is the most up-to-date and comprehensive text devoted solely to this disease and will be useful to medical oncologists, ophthalmologists, radiation therapists, interventional radiologists, pathologists, molecular biologists and immunology researchers, as well as trainees in those fields.
Uveitis
by George N. Papaliodis Uveitis is a practical guide for the diagnosis and treatment of uveitis and ocular inflammatory diseases. This text provides uveitis specialists, practicing ophthalmologists, and ophthalmology residents with the appropriate diagnostic testing and evidenced-based therapeutic options for managing patients afflicted with these conditions. The realm of ocular inflammatory diseases is constantly changing with improved diagnostic modalities and treatment options, however, despite these innovations, the ocular inflammatory diseases, including uveitis, are the third leading cause of blindness worldwide. Written and edited by leaders in the fields of ophthalmology, rheumatology, internal medicine, infectious disease, and oncology, Uveitis addresses the latest advances in the field, from the advent of PCR technology, intraocular depot steroid implants, neoplastic and infectious diseases masquerading as uveitis, and the use of systemic immunomoduatory therapies (including biologic agents/humanized monoclonal antibodies in the armamentarium).