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A Guide to Zona Pellucida Domain Proteins
by Eveline S. Litscher Paul M. WassarmanThis book provides a coherent, clear, and uniform presentation of structural, genetic, molecular, and biochemical information available for the zona pellucida domain protein family, which impact pathologies such as infertility, deafness, and cancer. Furthermore it: Details information about the structure and function of the ZP domain in ZPDC-proteins Provides illustrations of the organization of ZPDC-proteins, the genes that encode the proteins, and examples of mutations in the ZP domain that cause diseases Speculates as to the evolution of the ZP domain and potential therapeutics for diseases stemming from ZP domain mutations Addresses mammalian and non-mammalian systems
A Guide to the Extrapyramidal Side-Effects of Antipsychotic Drugs
by D. G. Cunningham OwensAntipsychotic drugs have revolutionised the management of major psychiatric disorders and the outcomes of those who suffer from them. They are, however, possessed of a range of adverse effects, amongst the most frequent and distressing of which are those resulting in disturbance of voluntary motor function. Extrapyramidal side effects - or E. P. S. - are still poorly recognised and not infrequently misattributed. Despite a vast research literature, there have been few attempts to bring together both the descriptive clinical elements of these disorders and major research conclusions pertinent to routine practice. This very readable and well illustrated 1999 book seeks to rectify this in the hope of increasing clinicians' awareness of the issues and acknowledgement of their impact. This is a task made more rather than less urgent with the emergence of drugs of lower liability but which may promote subtler abnormality than standard compounds.
A Guide to the Formulation of Plans and Goals in Occupational Therapy
by Sue Parkinson Rob BrooksThis practical guide for occupational therapists introduces a tried and tested method for moving from assessment to intervention, by formulating plans and measurable goals using the influential Model of Human occupation (MOHO). Section 1 introduces the concept of formulation – where it comes from, what it involves, why it is important, and how assessment information can be guided by theoretical frameworks and organised into a flowing narrative. Section 2 provides specific instructions for constructing occupational formulations using the Model of Human Occupation. In addition, a radically new way for creating aspirational goals is introduced - based on a simple acronym - which will enable occupational therapists to measure sustained changes rather than single actions. Section 3 presents 20 example occupational formulations and goals, from a wide range of mental health, physical health and learning disability settings, as well as a prison service, and services for homeless people and asylum seekers. Designed for practising occupational therapists and occupational students, this is an essential introduction for all those who are looking for an effective way to formulate plans and goals based on the Model of Human Occupation.
A Guide to the MRCP Part 2 Written Paper 2Ed
by Anthony Warrens Malcolm Persey Michael Fertleman Stephen PowisTrainees in preparation for the MRCP examination will welcome the much-anticipated new edition of this 'gold standard' revision book. Revised and updated throughout to encompass new developments in medical diagnostics and therapeutics, and restructured to reflect the recent changes in the format of the Part 2 written examination, the book continues
A Guide to the NHS
by Tony WhiteTo maximise the effectiveness of their work, NHS employees need a clear understanding of the structures and systems of the organisation in which they work. However, this information can be widely spread, hard to access and difficult to gain a working overview of, and the pace of changes and initiatives can seem almost dizzying. This book draws together a clear picture of the modern NHS, from funding and governance to reports, inquiries and overarching legislation. The book is clear and easy to understand and crucially includes full references to provide a one-stop point of access to the most detailed and up-to-date information available. This book is essential reading for workers in the NHS at all levels, including managers, administrators and clinical professionals. It is vital reading for managers and staff at commercial companies working with the NHS. It will also be of interest to campaigners, patient interest groups, researchers and journalists with an interest in the NHS. Specialty registrars and consultants can also find the information from the book, and much more, in The Doctor's Handbook Parts 1 & 2, by the same author. 'Rather than long narrative histories or complex explanations, the author signposts readers to sources of further information, making this book the quick guide so many of us need' - from the Foreword by Sir Ian Carruthers
A Guide to the Standard EMDR Therapy Protocols for Clinicians, Supervisors, and Consultants
by Andrew M. LeedsThis second edition of an acclaimed guide to the theory and practice of EMDR provides updated information regarding new evidence for its treatment efficacy and an in-depth presentation of state-of-the-art research on its mechanisms of action. The book reviews outcome studies suggesting EMDR's effectiveness for diagnoses beyond PTSD, along with studies on its use for treatment of depression, with cancer patients, and with groups. It surveys new strategies on advanced EMDR therapy topics such as when treating dissociative and personality disorders, along with references for more in-depth information. The second edition also provides an expanded glossary and extensively updated references and reflects changes corresponding to the DSM-5. <p><p>The book delivers clear, concise treatment guidelines for students, practicing clinicians, supervisors, clinic directors, and hospital administrators involved in the treatment of those with PTSD, specific phobias, and panic disorder. For researchers conducting treatment outcome studies, it provides easy-to-access treatment guidelines and a comprehensive set of fidelity checklists for all aspects of EMDR therapy. Many new charts, forms, scripts, illustrations, tables, and decision trees present key information clearly and concisely to guide treatment planning and documentation. Case studies with transcripts illustrate the different protocols and further guide practitioners of EMDR therapy in informed decision making.
A Guide to the World Anti-Doping Code
by Paul DavidWritten for those involved in sport, this book provides a guide to the fundamental principles of the World Anti-Doping Code and associated international standards and to the role of the Court of Arbitration for Sport and other national and international level sporting tribunals in adjudicating the code. After a summary of the history and a general overview of the code, chapters discuss the central role of the Prohibited List and then proceed to provide article-by-article commentary. Later chapters examine the possibility of challenges to the enforceability of the code and the process by which the provisions of the code are reviewed and amended. Annotation ©2009 Book News, Inc. , Portland, OR (booknews. com)
A Handbook Of Psychiatry (International Library Of Psychology)
by P.M. Lichtenstein S.M SmallThis is Volume XI of nineteen in collection of Abnormal and Clinical Psychology. Originally published in 1944, this book looks at the area of normality and abnormality. Normalcy is a relative term and its patterns vary continuously.
A Handbook for Action Research in Health and Social Care
by Richard Winter Carol Munn-GiddingsAction research is a form of research closely linked to practice which can readily be undertaken by practitioners and service users. This handbook offers a comprehensive guide to action research as a strategy for inquiry and development in health and social care. It can be used by individuals or groups working independently on their own projects or as a basis for a tutor-led course. It features* an introduction to the theories behind action research and other forms of research related to it*lively case studies from social work, nursing, mental health care and community work* a step-by-step study guide.The theoretical section of the book provides a general definition of action research, compares action research with other forms of social research, outlines the nature of a 'culture of inquiry' in the workplace, and describes the links between action research and service-user research, management,community development, evaluation, reflective practice, feminist research and anti-racist research.This practical study guide covers issues such as preparing a proposal, ethics and principles of procedure, gathering and analysing data, writing a report, the links between action research and critical reflection. It will be particularly useful for groups wishing to undertake action research on an independent basis
A Handbook for Support Workers in Health and Social Care: A Person-Centred Approach
by Paul Mackreth Bryony WalkerSupport workers are key deliverers of care in the UK, often hugely valued by those people they provide care for. Their roles and responsibilities are increasing in the midst of ever-changing health and social care systems. A Handbook for Support Workers in Health and Social Care recognises the contribution of support workers and provides an introduction to the core knowledge, legislation and models of practice required to work across health and social care settings. Covering core person-centred skills that a support worker needs to develop, this textbook looks at knowing and managing yourself, before moving on to understanding your role in the organisation and teamwork. It outlines the relevant legislation and policies, from the Care Act (2014) to confidentiality. Communication, both written and in person, is a central theme, and key values such as compassion and dignity are explored in relation to this. There is a thought-provoking discussion of working with people, covering topics including respecting choices, thinking about risk and safeguarding. The book ends by looking at what it means to be a competent practitioner and the importance of continual professional development. The first textbook introducing the core theory and practice knowledge necessary to work as a support worker in health and social care, it includes case studies, tasks and exercises to help the reader apply their learning. The authors share more than 20 years of experience in the design and delivery of support worker courses in higher education. They deliver continuing professional development, bespoke training and consultation to the health and social care workforce.
A Handbook for the Assessment of Children's Behaviours
by Peter D. Hill Jonathan O.H. WilliamsThis ground-breaking book takes a new approach to the assessment of behaviour in children and adolescents. Written by an expert author team, combining one (JW) with higher qualifications in general practice, child neuropsychiatry, and child and adolescent psychiatry, with one (PH) with higher qualifications in medicine, paediatrics and child and adolescent psychiatry, the book draws on many thousands of multidisciplinary case discussions, at Great Ormond Street Hospital, in the Children's Multispecialty Assessment Clinic in North London, and in private practice.The book is ideal for the busy mental health professional working in a small team. Organised to allow rapid look-up of behaviours with comprehensive lists of their possible causes, it synthesizes research evidence and clinical experience. The authors interpret behaviour broadly, including not just voluntary actions, but also actions whose voluntary nature is questionable (such as drop attacks, personal preferences, and pseudobehaviours). They also include problems that lead to referral through their behavioural manifestations (e.g. aggression, anxiety, or a poor relationship with mother). Overall, the book spans the behavioural, cognitive, social and emotional problems of children and adolescents.With the child and family in the room, and with detailed school reports and psychometric results available, it is usually possible to identify causes of symptoms that are specific to the child and his environment, and which can guide behavioural, cognitive, social, and family interventions.Purchasers of the book will also be entitled to a Wiley Desktop Edition--an interactive digital version featuring downloadable text and images, highlighting and note taking facilities, in-text searching, and linking to references and glossary terms.
A Handbook for the Sheep Clinician
by Agnes Winter Michael ClarksonAn established favourite with veterinary and agricultural students and a valuable addition to the library of any veterinarian or sheep farmer, this handbook covers the basics of sheep medicine and production. Geared at being an on-farm reference, it concisely conveys all of the fundamental information for the treatment of sheep worldwide. In this fully updated and revised 7th edition, topics covered include reproduction, vaccination, pregnancy and newborns, lameness, parasites, diseases, neurology and health promotion. An emphasis on diagnosis and treatment combined with short, easily digestible chapters and step-by-step diagrams makes this book an essential practical guide to recognising, treating and preventing disease.
A Handbook for the Sheep Clinician
An established favourite with veterinary and agricultural students and a valuable addition to the library of any veterinarian or sheep farmer, this handbook covers the basics of sheep medicine and production. Geared at being an easily accessed reference, it clearly conveys fundamental information on the care and treatment of sheep worldwide. This fully updated and revised eighth edition: - continues to cover all important aspects of sheep production and health, including reproduction, vaccination, pregnancy and newborns, lameness, internal and external parasites and flock health promotion; - reviews general developments and advancements in sheep veterinary medicine, as well as disease prevalence by geographical spread and in relation to changing climate; - considers topics of increasing importance such as vaccine availability and drug resistance. An emphasis on diagnosis and treatment combined with short, easily-digestible chapters and step-by-step diagrams makes this book an essential practical guide to recognizing, treating and preventing disease.
A Handbook for the Study of Mental Health (2nd edition)
by Teresa L. Scheid Tony N. BrownThe 2nd edition of A Handbook for the Study of Mental Health: Contexts, Theories, and Systems provides a comprehensive review of the sociology of mental health, with chapters written by leading scholars and researchers. The volume presents an overview of historical, social, and institutional frameworks for understanding mental health and illness. Part I examines social factors that shape psychiatric diagnosis and the measurement of mental health and illness, the theories that explain the definition and treatment of mental disorders, and cultural variability in mental health. Part II investigates effects of social context on mental health and illness. Individual chapters consider the role of social statuses including class, gender, race, and age. Several chapters focus on the critical role played by stress, marriage, work, and social support, with a concluding chapter focusing on terrorism. Part III focuses on the organization, delivery, and evaluation of mental health services, including a discussion of the criminalization of mental illness, the mental health challenges posed by HIV, and the importance of stigma in meeting the mental health needs of individuals. A Handbook for the Study of Mental Health is a key research reference source that will be useful to both undergraduates and graduate students studying mental health and illness from any number of disciplines.
A Handbook for the Study of Mental Health: Social Contexts, Theories, and Systems
by Wright Scheid Teresa L. Eric R.With chapters written by leading scholars and researchers, the third edition of A Handbook for the Study of Mental Health provides an updated, comprehensive review of the sociology of mental health. The volume presents an overview of the historical, social, and institutional frameworks for understanding mental health and illness. Part I examines the social factors that shape psychiatric diagnosis and the measurement of mental health and illness, the theories that explain the definition and treatment of mental disorders, and cultural variability in mental health. The section addresses the DSM-5 and its potential influence on diagnosis and research on mental health outcomes. Part II investigates the effects of social context on mental health and illness. Part III focuses on the organization, delivery, and social context of mental health treatment. The chapters in Part III address the likely impact of the Affordable Care Act on mental health care. This volume is a key resource for students, researchers, advocates, and policymakers seeking to understand mental health and mental health delivery systems.
A Handbook of Bioanalysis and Drug Metabolism
by Gary EvansRecent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.
A Handbook of Children and Young People's Participation: Perspectives from Theory and Practice
by Nigel Thomas Barry Percy-SmithA Handbook of Children and Young People's Participation brings together key thinkers and practitioners from diverse contexts across the globe to provide an authoritative overview of contemporary theory and practice around children’s participation. Promoting the participation of children and young people – in decision-making and policy development, and as active contributors to everyday family and community life – has become a central part of policy and programme initiatives in both majority and minority worlds. This book presents the most useful recent work in children’s participation as a resource for academics, students and practitioners in childhood studies, children’s rights and welfare, child and family social work, youth and community work, governance, aid and development programmes. The book introduces key concepts and debates, and presents a rich collection of accounts of the diverse ways in which children’s participation is understood and enacted around the world, interspersed with reflective commentaries from adults and young people. It concludes with a number of substantial theoretical contributions that aim to take forward our understanding of children’s participation. The emphasis throughout the text is on learning from the complexity of children’s participation in practice to improve our theoretical understanding, and on using those theoretical insights to challenge practice, with the aim of realising children’s rights and citizenship more fully.
A Handbook of Gene and Cell Therapy
by Clévio Nóbrega Liliana Mendonça Carlos A. MatosThis is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
A Handbook of Internet of Things in Biomedical and Cyber Physical System (Intelligent Systems Reference Library #165)
by Raghvendra Kumar Valentina E. Balas Vijender Kumar Solanki Md. Atiqur Rahman AhadThis book presents a compilation of state-of-the-art work on biomedical and cyber-physical systems in connection with the Internet of Things, and successfully blends theory and practice. The book covers the studies belonging to Biomedical and Cyber-physical System, so it is a unique effort by the research experts, who are divulging in the domain deeply. The book is very easy for the audience, who are doing study in the Biomedical and Cyber-physical System; it helps to read some real-time scenarios from where the reader in general gets many sparking ideas to convert it into the research problems in their studies. This book is of use to solve down the problems of graduate, postgraduate, doctoral industry executives, who are involving in the cutting-edge work of Internet of Things with Biomedical or Cyber-physical System, with the help of real-time solutions, given in the formation of chapters by subject’s experts.The key uses of this book are in the area of Internet of Things in connection with Cyber-physical System as well as Biomedical domain.
A Handbook of Transcription Factors: Handbook Of Transcription Factors (Subcellular Biochemistry #52)
by Timothy R. HughesTranscription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
A Handful of Ashes: Dr Harry Kent Book 2 (Dr Harry Kent thrillers)
by Rob McCarthyCrime's most original series character returns in a gripping new case. Dr Harry Kent is on the edge...He works too hard, sleeps too little, hardly sees daylight. And then the Met police call him out to certify the suicide of a whistleblower from a world-renowned London children's hospital - a trainee children's surgeon who accused her boss of negligence. Except someone held Susan Bayliss down... The grieving parents of the children who died demand answers. The hospital is stonewalling. Everyone has secrets - it's up to Harry and DCI Frankie Noble to find out which were worth killing for. But Harry's taking this personally... and that means trouble's on its way.
A Handful of Ashes: Dr Harry Kent Book 2 (Dr Harry Kent thrillers)
by Rob McCarthyThe second thrilling book in the London-set Dr Harry Kent series, the perfect mix of detective novel and medical drama. Susan Bayliss became notorious when she blew the whistle on her boss, a heart surgeon at a renowned children's hospital. She accused him of negligence, operations were stopped and an inquiry launched. In the end she was the one suspended as a troublemaker. Now Dr Harry Kent, a medical examiner with the Met Police, has been called out to certify her suicide. But something about the scene is wrong. Someone held Susan down... The grieving parents of the children who died demand answers. The hospital is stonewalling. Everyone has secrets - it's up to Harry and DCI Frankie Noble to find out which were worth killing for.(P) 2017 Hodder & Stoughton
A Hard Death: A Novel (Edward Jenner Series #2)
by Jonathan HayesForensic pathologist Edward Jenner survived the horrific ordeal of the Inquisitor serial slayings in New York, but not the political fallout. With his state medical license suspended, he hopes to repair his shattered life while working as a medical examiner in Douglas County, Florida. But evil is not confined to big cities alone.Two corpses pulled from a sunken car—followed by the grisly discovery of four more bodies hanging in the Everglades—are evidence of an insidious rot infecting this quiet coastal resort community. Suddenly Jenner's investigation is turning up grim traces of a nightmarish conspiracy—and with no one to trust and nowhere to turn, his only hope of survival is to walk away . . . something Jenner could never do.
A Health Economics Primer
by Shirley Johnson-LansCovers the key areas of health care economics - the supply and demand for health care and health insurance, the impact of technological innovation, and the role of institutions and public policy. It aims to enable instructors to adapt the course, with suggestions for ways to use this text along with essential readings covering research debates.
A Healthcare Solution: A Patient-Centered, Resource Management Perspective (Resource Management)
by Mark A. Vonderembse David D. DobrzykowskiThe evidence is undeniable. By any measure, the US spends more on healthcare than any other country in the world, yet its health outcomes as measure by longevity are in the bottom half among developed countries, and its health-related quality of life has remained constant or declined since 1998. In addition to high costs and lower than expected outcomes, the healthcare delivery system is plagues by treatment delays as it can take weeks to see a specialist, and many people have limited or no access to care. Part of the challenge is that the healthcare delivery system is a large, complex, and sophisticated value creation chain. Successfully changing this highly interconnected system is difficult and time consuming because the underlying problems are hard to comprehend, the root causes are many, the solution is unclear, and the relationships among problems, causes, and solution are multifaceted. To address these issues, the book carefully explains the underlying problems, examines their root causes using information, data, and logic, and presents a comprehensive and integrated solution that addresses these causes. These three steps are the methodological backbone of this book. A solution depends on understanding and applying the principles of patient-centered care (PCC) and resource management. PCC puts patients, supported by their primary care physicians, back in the role as decision makers and depends on patients being responsible for their health including making good life-style choices. After all, the best way to reduce healthcare costs and increase quality of life is to improve our health and wellness and as a result need less care. In addition, health insurance must be rethought and redesigned so it is less likely to lead to overuse. For many people with health insurance, the out-of-pocket cost of healthcare are small, so healthcare decision making is often biased toward consumption. Effective resource management means that healthcare providers must do a better job of acquiring and using resources in order to provide care quickly, productively, and correctly. This means improving healthcare strategy and management, accelerating the use of information technology, making drug costs affordable and fair, reducing the incidence of malpractice, and rebuilding the provider network.In addition, implementation is difficult because there are many participants in the healthcare delivery value chain, such as physicians, nurses, and medical technicians, as well as many provider organizations, such as hospitals, clinics, physician offices, and labs. Further up the value chain there are pharmaceutical companies, equipment providers, and other suppliers. These participants have diverse and sometimes conflicting goals, but each must be willing to accept change and work in a coordinated manner to improve healthcare. To overcome these problems, strong national leadership is needed to get the attention and support from the people and organizations involved in healthcare and to make the comprehensive changes that will lower healthcare costs, improve healthcare quality, eliminate delays, increase access, and enhance patient satisfaction.