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Amino Acids (Neuromethods #3)
by Alan A. Boulton Glen B. Baker James D. WoodThis book is about amino acids.
Amino Acids: Biochemistry and Nutrition
by Guoyao WuFollowing its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition presents exhaustive coverage of amino acids in the nutrition, metabolism and health of humans and other animals. Substantially revised, expanded and updated to reflect scientific advances, this book introduces the basic principles of amino acid biochemistry and nutrition, while highlighting the current knowledge of the field and its future possibilities. The book begins with the basic chemical concepts of amnio acids, peptides and proteins, and their digestion and absorption. Subsequent chapters cover cell-, tissue-, and species-specific synthesis and catabolism of amino acids and related bioactive metabolites, and the use of isotopes to study amino acids metabolism in cells and the body. The book details protein turnover, physiological functions of amino acids, as well as both the regulation and inborn errors of amino acid metabolism. The book concludes with a presentation on human and animal dietary requirements of amino acids and evaluates dietary protein quality. Features: Encompasses a comprehensive coverage of basic to applied concepts in amino acid metabolism in humans and other animals. Highlights important roles of dietary amino acids and protein intake in growth, physical performance and health, including sarcopenia mitigation and immunity. Discusses concerns over the excess intakes of amino acids or protein in the development of diseases, including cardiovascular disorders, diabetes and cancers, as well as bone integrity Each chapter contains select references to provide comprehensive reviews and original experimental data on the topics discussed. Each chapter is backed by original experimental data on various topics discussed and contains select references to aid the reader further in research. Written by Distinguished Professor of Animal Nutrition, Guoyao Wu, Ph.D., this book is an authoritative reference for students and researchers in both biomedicine and agriculture.
Amino Acids and Proteins for the Athlete: The Anabolic Edge (Nutrition in Exercise & Sport)
by Mauro G. Di PasqualeExtensively updated with all chapters rewritten and double the information and references, Amino Acids and Proteins for the Athlete: The Anabolic Edge, Second Edition reflects the nearly exponential increase in data and knowledge in the past few years regarding the use of amino acids and proteins to enhance athletic performance. This groundbreaking
Amino Acids and Proteins in Fossil Biominerals: An Introduction for Archaeologists and Palaeontologists (Analytical Methods in Earth and Environmental Science)
by Beatrice DemarchiAMINO ACIDS AND PROTEINS IN FOSSIL BIOMINERALS An essential cross-disciplinary guide to the proteins that form biominerals and that are preserved in the fossil record?? Amino Acids and Proteins in Fossil Biominerals is an authoritative guide to the patterns of survival and degradation of ancient biomolecules in the fossil record. The author brings together new research in biomineralization and ancient proteins to describe mechanisms of protein diagenesis. The book draws on the author's experiences as well as current information from three research fields: geochemistry, archaeology and Quaternary sciences. The author examines the history of the study of ancient proteins, from the dating of Quaternary biominerals to the present advances in shotgun proteomics, and discusses their applications across archaeology, geology and evolutionary biology. This important guide:?? Explores the main components of biominerals Describes the breakdown of proteins in fossils Reviews the applications of ancient protein studies Written for students and researchers of biomolecular archaeology and palaeontology, Amino Acids and Proteins in Fossil Biominerals provides a cross-disciplinary guide to the proteins responsible for the formation of biominerals and to the survival of biomolecules in the archaeological and palaeontological record. This book forms one volume of the popular New Analytical Methods in Earth and Environmental Science Series.
Amino Acids in Higher Plants
by G Osuji A Raychaudhuri Z-H He A. O Hudson C Sengupta-Gopalan S. M Duff F Gallardo E Gonzales-Vigil F. J Corpas Autar K. Mattoo R Hoefgen I Garcia Fernandez R Azevedo R Ingle L. V Nguyen E Planchet S Okumoto S Pfautsch J. W Chandler A Ishihara M Banon Arnao H Stotz S. O Duke D. A Saltmiras E Lewinsohn J Thomas S Rutherfurd S. C Minocha C. L LevesqueAmino acids play a role in the defence mechanisms and stress responses of plants, as well as in food quality and safety for humans and animals. Recent advances in the field make a comprehensive overview of the information a necessity; this book collates chapters on plant enzymes and metabolism, modulation, molecular aspects and secondary products. Also including information on ecology, the environment and mammalian nutrition and toxicology, it provides an authoritative resource.
Amino Acids in Higher Plants
by A Raychaudhuri D. A Saltmiras Z-H He L. V Nguyen G Osuji S. O Duke C. L Levesque Autar K. Mattoo A. O Hudson I Garcia Fernandez R Ingle J Thomas E Gonzales-Vigil S. C Minocha R Azevedo J D'Mello H Stotz S Pfautsch S Okumoto F Gallardo M Banon Arnao E Planchet S. M Duff C Sengupta-Gopalan F. J Corpas S Rutherfurd R Hoefgen E Lewinsohn J. W Chandler A IshiharaAmino acids play a role in the defence mechanisms and stress responses of plants, as well as in food quality and safety for humans and animals. Recent advances in the field make a comprehensive overview of the information a necessity; this book collates chapters on plant enzymes and metabolism, modulation, molecular aspects and secondary products. Also including information on ecology, the environment and mammalian nutrition and toxicology, it provides an authoritative resource.
Amino Acids in Nutrition and Health: Amino acids in systems function and health (Advances in Experimental Medicine and Biology #1265)
by Guoyao WuThis edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.
Amino Acids in Nutrition and Health: Amino Acids in the Nutrition of Companion, Zoo and Farm Animals (Advances in Experimental Medicine and Biology #1285)
by Guoyao WuAmino acids (AAs) are not only building blocks of protein, but are also signalling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health and well-being of individuals.Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Amino Acids in Nutrition and Health: Amino Acids in Gene Expression, Metabolic Regulation, and Exercising Performance (Advances in Experimental Medicine and Biology #1332)
by Guoyao WuThis book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.
Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry (Amino Acids, Peptides and Proteins in Organic Chemistry (VCH) #6)
by Andrew B. HughesThis is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis (Amino Acids, Peptides and Proteins in Organic Chemistry (VCH) #6)
by Andrew B. HughesThis is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Aminoacyl-tRNA Synthetases in Biology and Medicine (Topics in Current Chemistry #344)
by Sunghoon KimThis book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
Aminoglycoside Antibiotics A Guide To Therapy (Routledge Revivals)
by William G. Barnes and Glenn R. HodgesFirst Published in 1984, this book offers a full, comprehensive guide into the applications of Aminoglycoside Antibiotics in therapy. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.
Aminta: A Pastoral Play (Dual-language Poetry Series)
by Torquato Tasso Charles Jernigan Irene Marchegiani JonesTasso's masterpiece "Aminta" is perhaps the most famous pastoral play ever. It is also the work that launched the reputation of the author of the famed Italian epic poem of the First Crusade, Gerusalemme liberata. This story of satyrs and nymphs, shepherds and lovers is set in the ideal forest, far from the world of urban sophistication and decadence. It is presented here in the first Italian-English, dual-language edition of the play, and is the first new English translation published since the 19th century. Aminta's importance can not be overestimated; and its influence has been phenomenal, spawning over 200 plays by 1700 in Italy alone. This Italian pastoral is the source of numerous plays in France, Spain and England. Indirectly at least, it is also an inspiration for Shakespeare's pastoral comedies, such as "As You Like It," "Twelfth Night," and "A Midsummer Night's Dream." This volume is illustrated with the original woodcuts of the 1589 Aldine edition. Winner of the 2002 Premio Internazionale Diego Valeri of the Premio Monselice. DUAL-LANGUAGE POETRY. Introduction, notes, bibliography, illustrated.
Amir Khusraw: The Poet of Sultans and Sufis (Makers of the Muslim World)
by Sunil SharmaSurveys the life and lyrics of the 14th century Persian-speaking Indian poet.
Amir Sjarifoeddin: Politics and Truth in Indonesia, 1907-1948 (Cornell Modern Indonesia Project)
by Rudolf MrázekAmir Sjarifoeddin explores the experiences of a central figure in the Indonesian revolution, whose life mirrored the idealism and contradictions of the anti-colonial and post-war world of twentieth century Indonesia. Amir was born at the edge of an empire in a time of change. Imprisoned by the Dutch for anti-colonialism, he was sentenced to death by the Japanese for anti-fascism. He survived to become the prime minister of the new Indonesian republic. Disappointed by the direction the Indonesian elites were taking, Amir turned increasingly to the left. In 1948 he joined the armed uprising against both the Indonesian government and the corruption of the national revolution, and was captured and executed as a traitor. In Amir Sjarifoeddin, Rudolf Mrázek unveils the human dimensions of a figure who is widely mythologized but often poorly understood. Through Sjarifoeddin's life, it is possible to study the moral ambiguity and complexities of the political revolutions of the twentieth century.
Amiri Baraka: The Politics and Art of a Black Intellectual
by Jerry WattsAmiri Baraka, formerly known as LeRoi Jones, became known as one of the most militant, anti-white black nationalists of the 1960s Black Power movement. An advocate of Black Cultural Nationalism, Baraka supported the rejection of all things white and western. He helped found and direct the influential Black Arts movement which sought to move black writers away from western aesthetic sensibilities and toward a more complete embrace of the black world. Except perhaps for James Baldwin, no single figure has had more of an impact on black intellectual and artistic life during the last forty years. In this groundbreaking and comprehensive study, the first to interweave Baraka's art and political activities, Jerry Watts takes us from his early immersion in the New York scene through the most dynamic period in the life and work of this controversial figure. Watts situates Baraka within the various worlds through which he travelled including Beat Bohemia, Marxist-Leninism, and Black Nationalism. In the process, he convincingly demonstrates how the 25 years between Baraka's emergence in 1960 and his continued influence in the mid-1980s can also be read as a general commentary on the condition of black intellectuals during the same time. Continually using Baraka as the focal point for a broader analysis, Watts illustrates the link between Baraka's life and the lives of other black writers trying to realize their artistic ambitions, and contrasts him with other key political intellectuals of the time. In a chapter sure to prove controversial, Watts links Baraka's famous misogyny to an attempt to bury his own homosexual past. A work of extraordinary breadth, Amira Baraka is a powerful portrait of one man's lifework and the pivotal time it represents in African-American history. Informed by a wealth of original research, it fills a crucial gap in the lively literature on black thought and history and will continue to be a touchstone work for some time to come.
Amiri Baraka and the Congress of African People
by Michael SimangaThis important look at CAP combines historical research and analysis with the author's first-hand experience with the organization, providing the first historical narrative of a consequential player in the Black Power Movement.
Amirs, Admirals & Desert Sailors
by David F. WinklerHost to the U.S. Navy for nearly six decades, Bahrain has been a steadfast American ally in the turbulent Middle East. Its unique relationship with the United States evolved through a series of friendships between Bahrain s ruling Al Khalifa royal family and top U.S. Navy flag officers assigned to the fleet in the Gulf. Over the years it has become a strategic partnership critical to global security.As naval historian David F. Winkler examines these developing relationships, he offers a fascinating overview of Bahraini history, the entry of American humanitarian and economic interests, the establishment of an American naval presence in the Cold War, the Arab-Israeli conflicts, and the downfall of the Iranian shah, among other subjects. The author tells the story from both Bahraini and American perspectives.Given U.S. commitment to the region and its concurrent objectives of combating the global war on terrorism and establishing democracy, this book provides an important historical context for those interested in a crucial facet of American foreign relations. While many works describe the history of U.S. diplomatic and military involvement in the Gulf, this is the first to cover in depth the history of the U.S. Navy in Bahrain.
The Amish
by Donald B. Kraybill Karen M. Johnson-Weiner Steven M. NoltCompanion to the acclaimed PBS American Experience documentary.Winner of the CHOICE Outstanding Academic Title of the Choice ACRLThe Amish have always struggled with the modern world. Known for their simple clothing, plain lifestyle, and horse-and-buggy mode of transportation, Amish communities continually face outside pressures to modify their cultural patterns, social organization, and religious world view. An intimate portrait of Amish life, The Amish explores not only the emerging diversity and evolving identities within this distinctive American ethnic community, but also its transformation and geographic expansion.Donald B. Kraybill, Karen M. Johnson-Weiner, and Steven M. Nolt spent twenty-five years researching Amish history, religion, and culture. Drawing on archival material, direct observations, and oral history, the authors provide an authoritative and sensitive understanding of Amish society. Amish people do not evangelize, yet their numbers in North America have grown from a small community of some 6,000 people in the early 1900s to a thriving population of more than 320,000 today. The largest populations are found in Ohio, Pennsylvania, and Indiana, with additional communities in twenty-eight other states and three Canadian provinces. The authors argue that the intensely private and insular Amish have devised creative ways to negotiate with modernity that have enabled them to thrive in America. The transformation of the Amish in the American imagination from "backward bumpkins" to media icons poses provocative questions. What does the Amish story reveal about the American character, popular culture, and mainstream values? Richly illustrated, The Amish is the definitive portrayal of the Amish in America in the twenty-first century.
The Amish: A Concise Introduction (Young Center Books in Anabaptist and Pietist Studies)
by Steven M. NoltThe essential introduction to Amish life and culture.There seems to be no end to our fascination with the Amish, a religious minority that has both placed itself outside the mainstream of American culture and flourished within it. Yet most people know very little about the nuanced relationship the Amish have with society or their own communities. Drawing on more than twenty years of fieldwork and collaborative research, Steven M. Nolt’s The Amish: A Concise Introduction is a compact but richly detailed portrait of Amish life. In fewer than 150 pages, readers will come away with a clear understanding of the complexities of these simple people. Writing in engaging and accessible language, Nolt explains how the Amish at once operate within modern America and stand very much apart from the world. Arguing that Amish life is shaped equally by internal and external social, political, and economic contexts, Nolt explores Amish identity as emerging from a complex cultural negotiation with modernity. He takes on much-hyped topics such as Rumspringa and reveals the distinctive Amish approach to technology. He also explains how Amish principles stand in contrast to contemporary American values, including rational efficiency, large-scale organization, and Western notions of individuality. Authoritative, informative, and illustrated, this guide provides a vivid introduction to a way of life many find fascinating but few truly understand.
The Amish and Technology: An Excerpt from The Amish
by Donald B. Kraybill Karen M. Johnson-Weiner Steven M. NoltHopkins Digital Shorts deliver high-quality scholarship and compelling narratives in an abbreviated, electronic format. Whether excerpted from forthcoming or classic backlist titles or developed with newly commissioned content, Hopkins Digital Shorts provide concise introductions to fundamental concepts, defining moments, and influential texts.Limits on technology are the signature mark of twenty-first century Amish identity. Riding in horse-drawn buggies and living unplugged from the public grid unmistakably separate Amish people from mainstream Americans. Yet the Amish do not categorically condemn technology. Nor are they technologically naïve. Rather, Amish communities selectively sort out what might help or harm them. More significantly, the Amish modify and adapt technology in creative ways to fit their cultural values and social goals. Amish technologies are diverse, complicated, and ever-changing. This digital short explores the complicated relationship between the Amish and technology today.
Amish Baking: Traditional Recipes for Bread, Cookies, Cakes, and Pies
by Good Books100 authentic Amish yeast breads, quick breads, cakes, cookies, bars, pies, and more! Gathered from interviews with real Amish grandmothers, tattered recipe boxes, and old books and diaries, here is an assortment of delicious baked goods that have been and continue to be popular in eastern Pennsylvania, particularly in the Lancaster area. Now you too can experience the warm, comforting recipes of old order Amish cooks. Prepare to make wonderful treats such as: Potato BunsGlazed DoughnutsSchnitz PieShoofly PieHot Milk Sponge CakeMolasses CookiesOatmeal Whoopie PiesWhole Wheat BreadCorn BreadAnd more! These recipes will soon become your family favorites and go-to desserts for bake sales or potluck dinners. With simple ingredients and instructions that are easy to follow, you'll find yourself whipping up the same wonderful baked goods you can find in Amish markets or farm stands.
The Amish Blacksmith (Men of Lancaster County #2)
by Mindy Starns Clark Susan MeissnerNew from bestselling authors Mindy Starns Clark and Susan Meissner, The Amish Blacksmith (Book 2 in The Men of Lancaster County series) explores the men of an Amish community in Lancaster County, how their Amish beliefs play out in their unique roles, and the women who change their lives.<P><P> Apprenticed blacksmith Jake Miller is skeptical of Priscilla Kinsinger's innate ability to soothe troubled horses, especially when he has own ideas on how to calm them. Six years earlier, Priscilla's mother died in an awful accident at home, and Priscilla's grief over losing her mother was so intense that she was sent to live with relatives in Indiana. She has just returned to Lancaster County.<P> Not that her homecoming matters to Jake, who is interested in courting lighthearted Amanda Shetler. But Jake's boss is Priscilla's uncle, and when the man asks Jake to help his niece reconnect with community life, he has no choice but to do just that. Surprisingly, he finds himself slowly drawn to the beautiful but emotionally wounded Priscilla.<P> Jake then determines to prove to her that it's not her fault her mother died, but what he discovers will challenge everything they both believe about the depth of love and the breadth of forgiveness.