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Analytical Routes to Chaos in Nonlinear Engineering
by Albert C. LuoNonlinear problems are of interest to engineers, physicists and mathematicians and many other scientists because most systems are inherently nonlinear in nature. As nonlinear equations are difficult to solve, nonlinear systems are commonly approximated by linear equations. This works well up to some accuracy and some range for the input values, but some interesting phenomena such as chaos and singularities are hidden by linearization and perturbation analysis. It follows that some aspects of the behavior of a nonlinear system appear commonly to be chaotic, unpredictable or counterintuitive. Although such a chaotic behavior may resemble a random behavior, it is absolutely deterministic. Analytical Routes to Chaos in Nonlinear Engineering discusses analytical solutions of periodic motions to chaos or quasi-periodic motions in nonlinear dynamical systems in engineering and considers engineering applications, design, and control. It systematically discusses complex nonlinear phenomena in engineering nonlinear systems, including the periodically forced Duffing oscillator, nonlinear self-excited systems, nonlinear parametric systems and nonlinear rotor systems. Nonlinear models used in engineering are also presented and a brief history of the topic is provided. Key features: Considers engineering applications, design and control Presents analytical techniques to show how to find the periodic motions to chaos in nonlinear dynamical systems Systematically discusses complex nonlinear phenomena in engineering nonlinear systems Presents extensively used nonlinear models in engineering Analytical Routes to Chaos in Nonlinear Engineering is a practical reference for researchers and practitioners across engineering, mathematics and physics disciplines, and is also a useful source of information for graduate and senior undergraduate students in these areas.
Analytical Scientists in Pharmaceutical Product Development: Task Management and Practical Knowledge
by Kangping XiaoThis book explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. •Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. •Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. •Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment. This book explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. •Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. •Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. •Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment.
Analytical Similarity Assessment in Biosimilar Product Development
by Shein-Chung ChowThis book focuses on analytical similarity assessment in biosimilar product development following the FDA’s recommended stepwise approach for obtaining totality-of-the-evidence for approval of biosimilar products. It covers concepts such as the tiered approach for assessment of similarity of critical quality attributes in the manufacturing process of biosimilar products, models/methods like the statistical model for classification of critical quality attributes, equivalence tests for critical quality attributes in Tier 1 and the corresponding sample size requirements, current issues, and recent developments in analytical similarity assessment.
Analytical Skills for AI and Data Science: Building Skills for an AI-Driven Enterprise
by Daniel VaughanWhile several market-leading companies have successfully transformed their business models by following data- and AI-driven paths, the vast majority have yet to reap the benefits. How can your business and analytics units gain a competitive advantage by capturing the full potential of this predictive revolution? This practical guide presents a battle-tested end-to-end method to help you translate business decisions into tractable prescriptive solutions using data and AI as fundamental inputs.Author Daniel Vaughan shows data scientists, analytics practitioners, and others interested in using AI to transform their businesses not only how to ask the right questions but also how to generate value using modern AI technologies and decision-making principles. You’ll explore several use cases common to many enterprises, complete with examples you can apply when working to solve your own issues.Break business decisions into stages that can be tackled using different skills from the analytical toolboxIdentify and embrace uncertainty in decision making and protect against common human biasesCustomize optimal decisions to different customers using predictive and prescriptive methods and technologiesAsk business questions that create high value through AI- and data-driven technologies
Analytical Sociology
by Gianluca ManzoDemonstrates the power of the theoretical framework of analytical sociology inexplaining a large array of social phenomenaAnalytical Sociology: Actions and Networks presents the most advanced theoretical discussion of analytical sociology, along with a unique set of examples on mechanism-based sociology. Leading scholars apply the theoretical principles of analytical sociology to understand how puzzling social and historical phenomena including crime, lynching, witch-hunts, tax behaviours, Web-based social movement and communication, restaurant reputation, job search and careers, social network homophily and instability, cooperation and trust are brought about by complex, multi-layered social mechanisms. The analyses presented in this book rely on a wide range of methods which include qualitative observations, advanced statistical techniques, complex network tools, refined simulation methods and creative experimental protocols. This book ultimately demonstrates that sociology, like any other science, is at its best when it dissects the mechanisms at work by means of rigorous model building and testing. Analytical Sociology: * Provides the most complete and up-to-date theoretical treatment of analytical sociology.* Looks at a wide range of complex social phenomena within a single and unitary theoretical framework.* Explores a variety of advanced methods to build and test theoretical models.* Examines how both computational modelling and experiments can be used to study the complex relation between norms, networks and social actions.* Brings together research from leading global experts in the field in order to present a unique set of examples on mechanism-based sociology.Advanced graduate students and researchers working in sociology, methodology of social sciences, statistics, social networks analysis and computer simulation will benefit from this book.
Analytical Sociology and Social Mechanisms
by Pierre DemeulenaereMechanisms are very much a part of social life. For example, we can see that inequality has tended to increase over time, and that cities can become segregated. But how do such mechanisms work? Analytical sociology is an influential approach to sociology which holds that explanations of social phenomena should focus on the social mechanisms that bring them about. This book evaluates the major features of this approach, focusing on the significance of the notion of mechanism. Leading scholars seek to answer a number of questions in order to explore all the relevant dimensions of mechanism-based explanations in social sciences. How do social mechanisms link together individual actions and social environments? What is the role of multi-agent modelling in the conceptualization of mechanisms? Does the notion of mechanism solve the problem of relevance in social sciences explanations?
Analytical Solutions for Transport Processes: Fluid Mechanics, Heat and Mass Transfer (Mathematical Engineering)
by Günter BrennThis monograph provides analytical solutions to a number of classical problems in transport processes, i. e. in fluid mechanics, heat and mass transfer. Increasing computing power and efficient numerical methods have increased the importance of computational tools. However, the interpretation of these results is often difficult and the computational results need to be tested against the analytical results. This is why the analytical solutions are of high value. Furthermore, analytical solutions for transport processes provide a much deeper understanding of the physical phenomena of a given process than the corresponding numerical solution. The target audience primarily comprises researcher and practitioners but the book may also be beneficial for graduate students who want to enter the field.
Analytical Space: The Next Frontier?
by David Lane Thomas R. Eisenmann Jeffrey J. BussgangWith one satellite aloft and in the midst of beta testing in late 2018, Analytical Space founders Justin Oliveira and Dan Nevius turned to critical questions about the pioneering startup's go-to-market, pricing, and business development strategy. Analytical Space aimed to build and operate a constellation of inexpensive satellites that would receive and relay to the ground data gathered by orbiting Earth observation satellites, thereby speeding and increasing the amount of data their operators could collect and sell to clients in the multi-billion market for information on crops, weather, and other observable changes on Earth. The cofounders now needed to select the best initial customers, validate demand for their unique data relay service, and establish pricing that would both spur adoption and impress investors ahead of their next financing round.
Analytical Techniques and Methods for Biomass
by Sílvio Vaz Jr.This book deals with the application of techniques and methods of chemical analysis for the study of biomass and its conversion processes, aiming to fill the current gap in the book literature on the subject. The use of various techniques and analytical methods is presented and discussed in a straightforward manner, providing the reader with the possibility of choosing the most appropriate methodologies for analysis of the major classes of plant biomass and its products. In the present volume, a select group of international specialists describes different approaches to understand the biomass structure, their physical and chemical properties, the parameters of conversion processes, the products and by-products formation and quantification, quality parameters, etc. Modern chemistry plays a strong economic role in industrial activities based on biomass, with an increasing trend of the importance of its application from the deployment of biorefineries and the principles of green chemistry, which make use of the potential of biomass with decreasing impact negative environmental. In this context, analytical chemistry can contribute significantly to the supply chains of biomass, be it plant or animal origin; however, with the first offering the greatest challenges and the greatest opportunity for technical, scientific and economic progress, given its diversified chemical constitution. Thus, the chemical analysis can be used to examine the composition for characterizing physicochemical properties and to monitor their conversion processes, in order to obtain better products and uses of biomass. The quality of the biomass used determines the product quality. Therefore, reliable information is required about the chemical composition of the biomass to establish the best use (e. g. , most suitable conversion process and its conditions), which will influence harvest and preparation steps. Conversion processes should be monitored for their yield, integrity, safety, and environmental impact. Effluent or residues should be monitored and analyzed for environmental control. Co-products need to be monitored to avoid interference with the product yield and product purity; however, co-products are also a good opportunity to add value to the biomass chain. Finally, products need to be monitored and analyzed to determine their yields and purity and to ensure their quality. In this context, analytical chemistry can contribute significantly to the biomass supply chains, be it of plant or animal origin.
Analytical Techniques for Biopharmaceutical Development
by Stephen Tuck Tim Wehr Roberto Rodriquez-DiazThis reference assists scientists in the selection and application of analytical techniques for biopharmaceutical identification, formulation, and assessment-providing a valuable survey of exploratory methods commonly utilized during the preclinical, clinical, and commercial phases of development.
Analytical Techniques for Clinical Chemistry
by Sergio Caroli Gyula ZárayDiscover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.
Analytical Techniques for Natural Product Research
by Satyanshu KumarPlants are important source of lead molecules for drug discovery. These lead molecules serve as starting materials for laboratory synthesis of drug as well a model for production of biologically active compounds. Phytochemical processing of raw plant materials is essentially required to optimize the concentration of known constituents and also to maintain their activities. Extraction techniques and analytical techniques have played critical roles in phytochemical processing of raw materials. Extraction technologies from conventional extraction to green extraction as well as analytical techniques from single technique to hyphenated/coupled techniques most frequently used in phytochemistry laboratories are covered in the book.
Analytical Techniques for Natural Product Research
by Satyanshu KumarPlants are important source of lead molecules for drug discovery. These lead molecules serve as starting materials for laboratory synthesis of drug as well a model for production of biologically active compounds. Phytochemical processing of raw plant materials is essentially required to optimize the concentration of known constituents and also to maintain their activities. Extraction techniques and analytical techniques have played critical roles in phytochemical processing of raw materials. Extraction technologies from conventional extraction to green extraction as well as analytical techniques from single technique to hyphenated/coupled techniques most frequently used in phytochemistry laboratories are covered in the book.
Analytical Techniques for Studying the Physical Properties of Lipid Emulsions (SpringerBriefs in Food, Health, and Nutrition #3)
by Maria Lidia HerreraThis book will review old and new methods to study emulsion stability and structure. Examples of emulsion-based foods include ice cream, yoghurt, and mayonnaise. The physicochemical properties of emulsions play an important role in food systems, as they directly contribute to the texture, sensory and nutritional properties of foods. One of the main properties is stability, which refers to the ability of an emulsion to resist physical changes over time. The development of an effective strategy to prevent undesirable changes in the properties of a particular food emulsion depends on the dominant physicochemical mechanism(s) responsible for the changes. In practice, two or more of these mechanisms may operate in concert. It is therefore important for food scientists to identify the relative importance of each mechanism, the relationship between them, and the factors that influence them, so that effective means of controlling the stability and physicochemical properties of emulsions can be established. Several techniques are used to study the physical behavior and structure of emulsions. Each technique has its advantages and disadvantages and provides different insights into the destabilization mechanisms. Among the oldest methods used to study emulsion stability is visual observation and small deformation rheometry. More recently, other techniques, such as ultrasound profiling, microscopy, droplet size distribution, and measurement of surface concentration to characterize adsorbed protein at the interface, have also been employed. Some of these techniques, such as droplet size distribution, involve some form of dilution. However, dilution disrupts some structures that play an important role in stability. The ability to study the stability of food emulsions in their undiluted form may reveal subtle nuances about their stability. Diffusing wave spectroscopy (DWS), laser scanning confocal microscopy (LSCM), nuclear magnetic resonance (NMR), and Turbiscan are among the more powerful, non-perturbing techniques used to characterized emulsions.
Analytical Techniques for the Elucidation of Protein Function
by Isao Suetake Rohit K. Sharma Hironobu HojoANALYTICAL TECHNIQUES FOR THE ELUCIDATION OF PROTEIN FUNCTION An essential aid for scientists seeking alternative techniques for investigating proteins Proteins are the building blocks of living organisms, and they play an enormous range of fundamental roles in sustaining and shaping life. The critical determinant of a protein’s function is its structure, and the analysis of protein structures has therefore become a significant component of biological research. In recent years, longstanding analytical techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy have been supplemented by a number of new methods which promise to revolutionize the study of proteins and their functions. Analytical Techniques for the Elucidation of Protein Function serves as an introduction to these techniques, which are especially crucial for analyzing intrinsically disordered regions and post-translational modifications. These have revolutionized the study of proteins in recent years, and conventional methods for analyzing protein structures are no longer sufficient to work through their ramifications. This book therefore brings greater awareness of techniques which promise to produce the very cutting edge of protein research. Analytical Techniques for the Elucidation of Protein Function readers will find: A discussion of techniques including electron paramagnetic resonance (ESR) spectroscopy, neutron scattering, Raman imaging, and more Both theoretical background and practical applications for each technique Contributions from leading international researchers into protein structure and function This practically focused text is a valuable reference for protein and peptide analysis and synthesis researchers, as well as for graduate and advanced undergraduate students in the life sciences.
Analytical Techniques in Biochemistry (Springer Protocols Handbooks)
by Mahin BashaThis book provides a comprehensive overview of the major biochemical analytical techniques, with detailed descriptions of the instrumentation and applications. The contributions, which each focus on a specific technique, are based on a thorough review and analysis of the current literature as well as the authors’ experiences in the lab. Divided into nine parts, the book provides insights into basic separation techniques like sedimentation, filtration and centrifugation, as well as analytical techniques such as spectrophotometry, chromatography, electrophoresis, immuno-techniques, radioactivity and microscopy.
Analytical Techniques in Biochemistry and Molecular Biology
by Rajan KatochAdvances in biochemistry now allow us to control living systems in ways that were undreamt of a decade ago. This volume guides researchers and students through the full spectrum of experimental protocols used in biochemistry, plant biology and biotechnology.
Analytical Techniques in Electromagnetics
by Matthew N. Sadiku Sudarshan R. NelaturyAnalytical Techniques in Electromagnetics is designed for researchers, scientists, and engineers seeking analytical solutions to electromagnetic (EM) problems. The techniques presented provide exact solutions that can be used to validate the accuracy of approximate solutions, offer better insight into actual physical processes, and can be utilized
Analytical Techniques in Forensic Science
by Rosalind WolstenholmeAn in-depth text that explores the interface between analytical chemistry and trace evidence Analytical Techniques in Forensic Science is a comprehensive guide written in accessible terms that examines the interface between analytical chemistry and trace evidence in forensic science. With contributions from noted experts on the topic, the text features a detailed introduction analysis in forensic science and then subsequent chapters explore the laboratory techniques grouped by shared operating principles. For each technique, the authors incorporate specific theory, application to forensic analytics, interpretation, forensic specific developments, and illustrative case studies. Forensic techniques covered include UV-Vis and vibrational spectroscopy, mass spectrometry and gas and liquid chromatography. The applications reviewed include evidence types such as fibers, paint, drugs and explosives. The authors highlight data collection, subsequent analysis, what information has been obtained and what this means in the context of a case. The text shows how analytical chemistry and trace evidence can problem solve the nature of much of forensic analysis. This important text: Puts the focus on trace evidence and analytical science Contains case studies that illustrate theory in practice Includes contributions from experts on the topics of instrumentation, theory, and case examples Explores novel and future applications for analytical techniques Written for undergraduate and graduate students in forensic chemistry and forensic practitioners and researchers, Analytical Techniques in Forensic Science offers a text that bridges the gap between introductory textbooks and professional level literature.
Analytical Techniques in Meat Science
by M. Muthukumar V. V. Kulkarni P. S. Girish S. B. Barbuddhe B. M. NaveenaAnalytical Techniques in Meat Science is a comprehensive compilation of all the relevant methodologies for the quality analysis of meat. The content of the book is designed to cater to requirement of meat producers, regulatory agencies, researchers, students, teachers, laboratory staff etc. It covers techniques for physico-chemical analysis, speciesidentification and microbiological examination of meat. Also, it contains the latest biotechnological and proteomic techniques for meat quality evaluation. To help the reader understand better figures, tables, line diagrams, etc are used frequently whenever needed. Some important pictures are given in plates for lucid and clear understanding of theconcept.Note: T&F does not sell or distribute the hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.
Analytical Techniques in the Assessment of Credit Risk: An Overview of Methodologies and Applications (EURO Advanced Tutorials on Operational Research)
by Constantin Zopounidis Michalis Doumpos Christos Lemonakis Dimitrios NiklisThis book provides a unique, focused introduction to the analytical skills, methods and techniques in the assessment of credit risk that are necessary to tackle and analyze complex credit problems. It employs models and techniques from operations research and management science to investigate more closely risk models for applications within the banking industry and in financial markets. Furthermore, the book presents the advances and trends in model development and validation for credit scoring/rating, the recent regulatory requirements and the current best practices. Using examples and fully worked case applications, the book is a valuable resource for advanced courses in financial risk management, but also helpful to researchers and professionals working in financial and business analytics, financial modeling, credit risk analysis, and decision science.
Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring
by Melissa N. Dunkle William L. WinnifordA thorough introduction to environmental monitoring in the oil and gas industry Analytical Techniques in the Oil and Gas Industry for Environmental Monitoring examines the analytical side of the oil and gas industry as it also provides an overall introduction to the industry. You’ll discover how oil and natural gas are sourced, refined, and processed. You can learn about what’s produced from oil and natural gas, and why evaluating these sourced resources is important. The book discusses the conventional analyses for oil and natural gas feeds, along with their limitations. It offers detailed descriptions of advanced analytical techniques that are commercially available, plus explanations of gas and oil industry equipment and instrumentation. You’ll find technique descriptions supplemented with a list of references as well as with real-life application examples. With this book as a reference, you can prepare to apply specific analytical methods in your organization’s lab environment. Analytical Techniques can also serve as your comprehensive resource on key techniques in the characterization of oil and gas samples, within both refinery and environmental contexts. Understand of the scope of oil and gas industry techniques available Consider the benefits and limitations of each available process Prepare for applying analytical techniques in your lab See real examples and a list of references for each technique Read descriptions of off-line analytics, as well as on-line and process applications As a chemist, engineer, instructor, or student, this book will also expand your awareness of the role these techniques have in environmental monitoring and environmental impact assessments.
Analytical Techniques in the Pharmaceutical Sciences (Advances in Delivery Science and Technology)
by Yvonne Perrie Thomas Rades Anette MüllertzThe aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e. g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.
Analytical Testing for the Pharmaceutical GMP Laboratory
by Kim Huynh-BaProvides practical guidance on pharmaceutical analysis, written by leading experts with extensive industry experience Analytical Testing for the Pharmaceutical GMP Laboratory presents a thorough overview of the pharmaceutical regulations, working processes, and drug development best practices used to maintain the quality and integrity of medicines. With a focus on smaller molecular weight drug substances and products, the book provides the knowledge necessary for establishing the pharmaceutical laboratory to support Quality Systems while maintaining compliance with Good Manufacturing Practices (GMP) regulations. Concise yet comprehensive chapters contain up-to-date coverage of drug regulations, pharmaceutical analysis methodologies, control strategies, testing development and validation, method transfer, electronic data documentation, and more. Each chapter includes a table of contents, definitions of acronyms, a reference list, and ample tables and figures. Addressing the principal activities and regulatory challenges of analytical testing in the development and manufacturing of pharmaceutical drug products, this authoritative resource: Describes the structure, roles, core guidelines, and GMP regulations of the FDA and ICH. Covers the common analytical technologies used in pharmaceutical laboratories, including examples of analytical techniques used for the release and stability testing of drugs. Examines control strategies established from quality systems supported by real-world case studies. Explains the use of dissolution testing for products such as extended-release capsules, aerosols, and inhalers. Discusses good documentation and data reporting practices, stability programs, and the Laboratory Information Management System (LIMS) to maintain compliance. Includes calculations, application examples, and illustrations to assist readers in day-to-day laboratory operations. Contains practical information and templates to structure internal processes or common Standard Operating Procedures (SOPs). Analytical Testing for the Pharmaceutical GMP Laboratory is a must-have reference for both early-career and experienced pharmaceutical scientists, analytical chemists, pharmacists, and quality control professionals. It is also both a resource for GMP laboratory training programs and an excellent textbook for undergraduate and graduate courses of analytical chemistry in pharmaceutical sciences or regulatory compliance programs.
Analytical Thermodynamics
by Dongqing LiThis book provides the foundations of analytical thermodynamics for graduate level. The content is based on the author’s lecture notes developed over 30 years of academic teaching. It aims to present thermodynamics to the readers as easy to understand as possible, being suitable for professors teaching advanced thermodynamics or graduate students learning thermodynamics. The chapters include the basics of analytical thermodynamics, modelling of homogeneous and heterogeneous systems, thermodynamics of interfaces and three-phase contact lines and the Second Law in engineering thermodynamics.