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Bioactive Lipids in Health and Disease (Advances in Experimental Medicine and Biology #1127)
by Andres Trostchansky Homero RubboThe purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology
Bioactive Molecules in Food (Reference Series in Phytochemistry)
by Kishan Gopal Ramawat Jean-Michel MérillonThis reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable case studies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.
Bioactive Molecules in Plant Defense: Saponins
by Mostafa Abdelrahman Sudisha JogaiahThis book presents a broad perspective on saponins as important natural products with a key role in plant defense. The presence of saponins has been reported in several plant species, and many types of saponins have been found to exhibit significant antifungal activities. In addition to their role in plant defense, saponins are of increasing interest for drug research, as they are active ingredients in several traditional medicines and hold potentially valuable pharmacological properties. In this book, the authors briefly introduce readers to saponin accumulation in various plant organs, with a specific focus on their structure classification and diversity. Readers will find detailed information on the saponin structure-activity relationship and saponins’ vital role in sustainable agriculture as a chemical barrier to pathogen attack. The latest techniques for isolating, identifying, and quantifying saponins are also discussed. In the closing chapter, the authors outline the recent metabolic engineering strategies applied to improve saponin glycosides production and their potential applications in plant disease resistance.This book and the companion volume Bioactive Molecules in Plant Defense: Signaling in Growth and Stress offer vital resources for all researchers and students interested in plant pathology, mycology and sustainable agriculture.
Bioactive Molecules in Plant Defense: Signaling in Growth and Stress
by Mostafa Abdelrahman Sudisha JogaiahThis book focuses on signaling molecules in plant defense, outlining some of the most important cellular and chemical plant defense strategies during periods of stress and growth. Written by leading experts, it covers topics such as the diversity of plant-growth-promoting fungi, the gene-to-metabolite network of plant-microbe interactions, modulation of plant cellular responses to stress, and how plant nutritional deficiency affects crop production. Together with the companion volume Bioactive Molecules in Plant Defense: Saponins, this book offers an essential source of information for postgraduate students and researchers interested in plant pathology, mycology and sustainable agriculture.
Bioactive Natural Products
by Goutam BrahmachariNatural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell.This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes.Key features:Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural productsFeatures chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biologyForward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving fieldApplication-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnologyThis book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Bioactive Natural Products for Pharmaceutical Applications (Advanced Structured Materials #140)
by Amit Kumar Nayak Dilipkumar PalThis book covers the recent innovations relating to various bioactive natural products (such as alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, volatile oils, fixed oils, fats and waxes, proteins and peptides, vitamins, marine products, camptothecin, piperines, carvacrol, gedunin, GABA, ginsenosides) and their applications in the pharmaceutical fields related to academic, research and industry.
Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
by Anil K. SharmaThis book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms. Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.
Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition
by Steven M. Colegate Russell J. MolyneuxFollowing the successful format of the original, this new edition presents applications of the most recent techniques for the detection, isolation, and structural determination of bioactive natural products. It features new case studies and illustrations that demonstrate applications of techniques covered in the book. Complementing as much as replacing the first edition, most of the contributors are new. The text includes updates on chemical extraction, and NMR-based structure determination, and new contributions on liquid chromatography linked with mass and NMR spectroscopy, dereplication approaches, assessment of source material for natural products and novel bioassay development.
Bioactive Natural products in Drug Discovery
by Joginder Singh Vineet Meshram Mahiti GuptaThis book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.
Bioactive Peptides from Food: Sources, Analysis, and Functions (Food Analysis & Properties)
by Leo M.L. Nollet and Semih ÖtleşA growing body of scientific evidence has revealed that many food peptides exhibit specific biological activities in addition to their established nutritional value. Bioactive peptides present in foods may help reduce the worldwide epidemic of chronic diseases that account for a great number of premature deaths annually. Bioactive peptides can be defined as isolated small fragments of proteins which provide some physiological health benefits. They act as potential modifiers reducing the risk of many chronic diseases. Bioactive Peptides from Food: Sources, Analysis, and Functions considers fundamental concepts, sources, hydrolysis, fractionation, purification, analysis, chemical synthesis, functions, and regulatory status of nutraceutical bioactive peptides. Methods of isolation of these peptides from different protein sources with their in vitro and vivo physiological effects are addressed. Divided into seven sections, this book delves into how these peptides play a major role in the development of various functional foods. Numerous bioactive peptides have been reported in recent years as naturally present or generated from food proteins of different origins like milk, eggs, soya, fish, and meat. Key Features: Includes a detailed study of the different sources of bioactive peptides Discusses the health benefits, such as antimicrobial, antiallergic, antihypertensive, antitumor, and immunomodulatory properties of peptides Explorates the state of the art analysis methods of peptides Discovers the bioinformatics of possible bioactive peptides Written by experts in their field from around the world, Bioactive Peptides from Food reveals the world of databases of peptides. It is a great resource for food scientists, technologists, chemists, nutrition researchers, producers, and processors working in the whole food science and technology field as well as those who are interested in the development of innovative functional products.
Bioactive Peptides: Applications for Improving Nutrition and Health
by Richard Owusu-ApentenChronic illnesses, injury, or infections produce a decline in muscle massleading to delayed recovery, more post-treatment complications, longer hospital stays, and higher mortality rates. Therefore, ensuring adequate lean body mass is of major concern in health care. Presenting data from human studies and trials, along with recent research findings
Bioactive Peptides: Production, Bioavailability, Health Potential, and Regulatory Issues (Nutraceuticals)
by Yashwant V. Pathak M. Selvamuthukumaran John Oloche OnuhBioactive peptides have been receiving attention recently due to their applications as health-promoting agents. Derived from food proteins and other natural sources, they exhibit various beneficial effects such as preventing diseases or modulating physiological systems once absorbed. As the market for nutraceuticals and functional foods continues to expand, consumer interest has also grown and there are many common foods that have shown an abundance of bioactive peptides, including dairy products, cereal, legumes, meat, and numerous other sources. In this newest addition to the series Nutraceuticals: Basic Research and Clinical Applications, Bioactive Peptides: Production, Bioavailability, Health Potential, and Regulatory Issues provides a comprehensive review of the current state of knowledge in the field of food protein hydrolysates and bioactive peptides, their food sources, bioavailability, production, applications, functionalities, health potentials, and regulatory issues governing their use. Features Discusses different methodologies employed for scaling up bioactive peptides commercially Provides information on optimizing the production process Explains various bioactive properties exerted by different types of bioactive peptides Explores the application of metabolomics to the study of bioactive peptides With over 20 chapters written by established subject matter experts in their field, this book provides timely information and discusses the latest developments of bioactive peptides. It will be useful for researchers, academics, and industry experts, and can serve as an excellent resource for anyone interested in enhancing their knowledge in the field of bioactive peptides.
Bioactive Phytochemicals from Vegetable Oil and Oilseed Processing By-products (Reference Series in Phytochemistry)
by Mohamed Fawzy Ramadan HassanienThis book comprehensively reviews the phytochemistry, functional properties, and health-promoting effects of bioactive compounds found in oil processing by-products, and it also explores the food and non-food applications of these by-products. Several oilseeds, vegetables, and fruits are cultivated for their oils and fats, wherein the oil extraction industry generates a huge amount of waste (meal or cake). The valorisation of this waste would be very beneficial not only from the economic and environmental perspectives, but also for the potential applications in food, cosmetics and pharmaceutical industries, in which phytochemicals derived from vegetable oil and oilseed processing by-products play an important role in, for instance, extending the shelf life of several products and providing added-value properties with their antioxidant and antimicrobial properties. In this work, expert contributors discuss about the added-value of biowaste from common and non-traditional vegetable oils and oilseeds processing, as well as fruit oils processing, and offer an extensive overview of the different bioactive compounds found in extracts from oil processing by-products and their chemical composition. The book also collects several examples in which oil processing by-products are integrated into industrial activities such as food production, livestock production and in pharmaceutical and cosmetics industries. Professionals and scholars alike interested in the recycling of agro-industrial wastes derived from vegetable oil and oilseed processing by-products will find this book a handy reference tool.
Bioactive Phytochemicals in By-products from Bulb, Flower and Fruit Vegetables
by Mohamed Fawzy RamadanThis book collates bioactive compounds from the by-products of bulb, flower and fruit vegetables, and it explores vegetable processing by-products utilization. By-products and wastes from vegetable processing have been gathering attention in the food industry due to the management of residues that pose significant disposal challenges. This book not only addresses these concerns but also underscores the potential of these by-products as sources of value-added phytochemicals, with a focus on the recovery of bioactive phytochemicals and technologically critical secondary metabolites. This book covers vegetable by-products’ economic significance, ecological implications, and their applications spanning nutrition, health, and industry. Divided into 13 chapters, the book offers an overview of the phytochemical, nutritional, biochemical and physicochemical properties of vegetable processing wastes. It discusses process by-products of diverse vegetables, including fennel, garlic, onion, artichoke, cauliflower, broccoli, bitter melon, bell pepper, chili pepper, chayote, cucumber, eggplant, green plantain banana, pumpkin and tomato. In each chapter, readers will find an economic perspective for each biowaste, the chemical analysis of the bioactive compounds, their biological and functional properties, and relevant food and non-food applications of extracts and bioactive compounds from vegetable by-products. This book, coupled with its companion volume, "Bioactive Phytochemicals in By-products from Leaf, Stem, Root, and Tuber Vegetables," serves as an indispensable resource for students, scholars, and researchers seeking to deepen their understanding of this research area. It also extends its relevance to professionals within the food industry, offering the latest insights and findings from cutting-edge research.
Bioactive Phytochemicals in By-products from Leaf, Stem, Root and Tuber Vegetables
by Mohamed Fawzy RamadanThis book offers a comprehensive overview of bioactive phytochemicals within by-products from leaf, stem, root, and tuber vegetables, and it explores the valorisation of these vegetable cultivation and processing by-products, not only as a source of valuable bioenergy but also for health purposes. Divided into 16 chapters, the book begins with an introduction to the economic significance of biowaste generated from vegetable cultivation and processing, setting the stage for subsequent chapters that cover the phytochemical, nutritional, biochemical and physicochemical properties of vegetable processing wastes and their multifaceted applications. Readers will find valuable insights into the valorisation of process by-products from diverse vegetables like cabbage, spinach, watercress, asparagus, celery, kohlrabi, beetroot, carrot, celeriac, turnip, sweet potato, potato and taro. In each chapter, readers will find an economic perspective for each biowaste, the chemical analysis of the bioactive compounds, their biological and functional properties, and relevant food and non-food applications of extracts and bioactive compounds from vegetable by-products. This book, coupled with its companion volume, " Bioactive Phytochemicals in By-products from Bulb, Flower and Fruit Vegetables" serves as an indispensable tool for students, scholars, and researchers seeking to expand their knowledge within this field in agricultural and nutritional sciences. It also extends its relevance to professionals within the food industry, offering the latest insights and findings from cutting-edge research.
Bioactive Polyphenols from Wine Grapes (SpringerBriefs in Cell Biology)
by Ellen L Robb Jeffrey A StuartIs red wine good for you? And if so, why? How much? And what are the actual benefits? This addition to the SpringerBriefs in Cell Biology series thoroughly but succinctly answers these questions. It covers the biochemistry, health benefits and therapeutic potential of wine grapes. It begins with an overview of phytoalexin production in Vitis vinifera (Common Grape Vine), detailing the relationship of resveratrol to analogues such as pterostilbene, piceid and the viniferins (resveratrol oligomers). The discussion then turns to the hundreds of reports linking resveratrol and related grape vine polyphenols to various beneficial health effects especially cardio- and cerebro- vascular, metabolic, anti-inflammatory and more. Also addressed are the numerous intracellular mechanisms that have been shown to mediate the effects of these compounds in mammalian cells and tissues. Finally, the authors discuss aspects of polyphenol bioavailability and how this will influence choices taken for delivering these compounds as nutritional supplements. A brief chapter containing general conclusions and prospectus rounds out the information.
Bioactive Polysaccharide Materials for Modern Wound Healing (Springerbriefs In Molecular Science: Chemistry of Foods)
by Tina Maver Uroš Maver Tanja Pivec Manja Kurečič Zdenka Peršin Karin Stana KleinschekThis is the first concise book that includes different aspects of naturally-derived components for wound healing. It presents the first exhaustive review of modern techniques in wound dressing development. With a growing, ageing population and the rapid growth of the wound-care market, the authors explore the current trend of bio-based products (active components and host materials) in this field. After a short introduction into modern solutions in wound-care and modern techniques in wound-dressing development, the authors, leaders in the field, explore natural-based components (drugs, extracts, materials etc.); safety and efficiency assessments (biocompatibility, cytotoxicity and in vitro performance etc.); and model films as a platform for the development of new wound dressings.
Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals (Institute of Food Technologists Series #29)
by Eunice Li-Chan Yoshinori Mine Bo JiangBioactive Proteins and Peptides as Functional Foods and Nutraceuticals highlights recent developments of nutraceutical proteins and peptides for the promotion of human health. The book considers fundamental concepts and structure-activity relations for the major classes of nutraceutical proteins and peptides. Coverage includes functional proteins and peptides from numerous sources including: soy, Pacific hake, bovine muscle, peas, wheat, fermented milk, eggs, casein, fish collagen, bovine lactoferrin, and rice. The international panel of experts from industry and academia also reviews current applications and future opportunities within the nutraceutical proteins and peptides sector.
Bioactive Secondary Metabolites from Medicinal Plants of Africa (Interdisciplinary Biotechnological Advances)
by Aman DekeboThis book provides a comprehensive overview of bioactive compounds derived from African traditional medicinal plants, shedding light on their potential applications in modern medicine. It compiles crucial information on compounds with proven in vitro and in vivo activity against various diseases, providing a foundation for further research in drug discovery. The book also introduces the use of these bioactive secondary metabolites in cosmetics, nutrition, and pest control, with detailed description of medicinal plant species, including their botanical names, ethnomedicinal uses, and pharmacological activities, making it an invaluable resource for researchers and pharmaceutical companies. Key concepts include the exploration of secondary metabolites from plants in Ethiopia, Egypt, Kenya, Uganda, Zimbabwe, Cameroon, Tanzania, Madagascar, and Nigeria, and their industrial applications. The chapters cover ethnobotanical knowledge, bioactivities, and chemical profiling of these plants, including the ethnobotanical and phytochemical studies of Ethiopian flora, the role of rose-scented geranium in the perfume industry, and the use of fruits and vegetables in treating respiratory ailments. Readers will also discover insights into the use of secondary metabolites for pest control, the conservation strategies for endangered African plants, and the synthesis of bio-nanoparticles for therapeutic applications. The book presents a detailed analysis of medicinal plants with anti-malarial, antileishmanial, improve sexual desire and antimicrobial properties, highlighting their significance in traditional and modern medicine. This volume is an essential resource for researchers, graduate students, and professionals in the fields of natural products, phytochemistry, and pharmaceuticals. It provides a unique perspective on the integration of traditional African medicine with contemporary scientific research, offering valuable insights into the potential of these bioactive compounds in drug development.
Bioactive Sphingolipids in Cancer Biology and Therapy
by Yusuf A. Hannun Chiara Luberto Cungui Mao Lina Marie ObeidThis volume presents information on both the basic and clinical aspects of sphingolipid-metabolizing enzymes in various cancers. The volume also includes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer.
Bioactive Surfaces (Advances in Polymer Science #240)
by Jean-Francois Lutz Hans G. BörnerErik Wischerhoff, Nezha Badi, André Laschewsky and Jean-François Lutz Smart Polymer Surfaces: Concepts and Applications in Biosciences; S. Petersen, M. Gattermayer and M. Biesalski Hold on at the Right Spot: Bioactive Surfaces for the Design of Live-Cell Micropatterns; Julien Polleux Interfacing Cell Surface Receptors to Hybrid Nanopatterned Surfaces: A Molecular Approach for Dissecting the Adhesion Machinery; Abigail Pulsipher and Muhammad N. Yousaf Self-Assembled Monolayers as Dynamic Model Substrates for Cell Biology; D. Volodkin, A. Skirtach and H. Möhwald LbL Films as Reservoirs for Bioactive Molecules; R. Gentsch and H. G. Börner Designing Three-Dimensional Materials at the Interface to Biology; Joerg C. Tiller Antimicrobial Surfaces;
Bioactive-Based Nanotherapeutics
by Rakesh K. Sindhu Sumitra Singh Evren Algin YaparThe book provides essential insights into the revolutionary potential of nanotechnology in medicine, exploring innovative approaches that harness natural materials for targeted and effective disease management. Nanotechnology has emerged as an innovative field with the potential to transform various sectors, including medicine and allied health sciences. Bioactive nanotherapeutics, a specific area within nanotherapeutics, utilizes natural materials or biomimetic designs to offer distinct advantages such as targeted drug delivery, biocompatibility, and improved therapeutic efficacy. These bioactive-based nanotherapeutics are used in the treatment and management of various diseases. Bioactive-Based Nanotherapeutics explores this rapidly growing field of therapeutics. It presents a broad overview of the fundamentals of bioactive nanomaterials, their design strategies, and their therapeutic applications. Leading experts from different disciplines have contributed chapters that explore a diverse range of topics, including the basics of bioactive nanotherapeutics, isolation methods of different bioactive compounds, and formulation developments. This volume addresses the importance of nanotechnology for the treatment and management of different diseases, including nasal, gastrointestinal, rectal, and transdermal diseases. Readers will find the book: Provides scientific research and evidence that supports the effectiveness of bioactive-based nanocarriers in treating diseases; Explores actionable steps and real-life scenarios to illustrate the practical benefits; Provides a comprehensive guide that explains the holistic approach, explaining health-related applications of bioactive-based nanoformulations. Audience Pharmacists, biologists, chemists, doctors, academics, and industry professionals interested in holistic and bioactive-based methods for disease treatment.
Bioactives Encapsulation: Food Applications (Methods and Protocols in Food Science)
by Samantha Cristina de Pinho Carmen Silvia Favaro-TrindadeThe purpose of this book is to give a comprehensive introduction into methods and procedures on the production of micro and nanoencapsulation systems suitable for posterior incorporation in food products. Written in the format of the Methods and Protocols in Food Science series, the chapters include an introduction to the respective topic, list necessary materials and reagents, detail well established and validated methods for readily reproducible laboratory protocols and contain notes on how to avoid or solve typical problems. Authoritative and cutting-edge, Bioactives Encapsulation: Food Applications aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Bioactives in Fruit: Health Benefits and Functional Foods
by Denise Hunter Margot SkinnerFor centuries we have known that fruit is important for health, but we are only just beginning to fully understand why. Bioactives in Fruit: Health Benefits and Functional Foods aims to summarise some of our current knowledge on the bioactive compounds that are associated with the health benefits of specific fruits with a strong emphasis on the validation of health benefits by human intervention trials. Reflecting the current interest in food and health, the book includes strategies to retain and enhance the bioactives in fruit through breeding, growing conditions, fruit storage, processing into ingredients and production of functional foods. To accomplish this task authors with expertise in biology, chemistry, pharmacology, food science, nutrition, medicine, and horticulture have contributed. They come from universities, government and industry funded research institutes and biotechnology and food companies in Europe, the United States, Asia and New Zealand to give the book a broad perspective. This book, describing fruit bioactives, their health benefits when consumed as a food and related topics regarding their development into fresh or processed functional foods, will be of use to postgraduate students, researchers, functional food product developers, food regulators and anyone who has curiosity about why fruit is good for you. The information contained within will provide plant breeders with new targets for the development of value-added horticultural products, and will also provide nutritionists and dieticians with a useful resource for developing strategies to assist in preventing or slowing disease onset or severity. Bioactives in Fruit: Health Benefits and Functional Foods is a major resource which will be required reading for anyone working in the fields of health and functional foods.
Bioactivity of Engineered Nanoparticles (Nanomedicine and Nanotoxicology)
by Bing Yan Hongyu Zhou Jorge L. Gardea-TorresdeyThis book brings together reviews from international experts who are exploring the biological activities of nanomaterials for medical applications or to better understand nanotoxicity. Topics include but are not limited to the following: 1) mechanistic understanding of nanostructure-bioactivity relationships; 2) the regulation of nanoparticles' bioactivity by means of chemical modification; 3) the new methodologies and standard methods used to assess nanoparticles' bioactivity; 4) the mechanisms involved in nanoparticle-biomolecule interactions and nanoparticle-cell interactions; and 5) biomedical applications of nanotechnology. The book will be a valuable resource for a broad readership in various subfields of chemical science, engineering, biology, environment, and medicine.