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Cancer: A Comprehensive Textbook of Cancer’s Causes, Complexities and Consequences
by Carolyn ComptonThis comprehensive, ground-breaking title presents, in simplifying style, the driving and organizing principles of cancer, making this multidimensional, highly complex disease easily understandable for readers. Developed out of the renowned author’s many years of teaching a widely popular, several-hundred-student college course, this 12-chapter book begins with an account of the history of cancer as a medical and public health problem, as well as the major milestones and setbacks in the ongoing quest to understand the wide variety of cancers that continue to impact the world. Subsequent chapters then address pathogenesis, incidence and mortality statistics, risk factors, causal factors, screening challenges and victories, treatment strategies, and disease prevention approaches. This wealth of clinical information is further supplemented with socioeconomic discussions on the financial, social, ethical, technological, regulatory, political, and logistical challenges that limit progress in cancer research. A soon to be gold-standard text that thoroughly and expertly describes cancer as a composite, adaptive system, Cancer: The Enemy from Within equips and empowers all undergraduate students and graduate students to better understand this continually perplexing disease. Clinicians across all disciplines may also find this work of great interest.
Cancer: Basic Science and Clinical Aspects
by Sheila A. Barry Craig A. Almeida“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.
Cancer: Prevention, Early Detection, Treatment and Recovery
by Gary S. Stein Kimberly P. LuebbersA guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.
Candace Pert: Genius, Greed, and Madness in the World of Science
by Pamela RyckmanCandace Pert stood at the dawn of three revolutions: the opioid crisis, the AIDS crisis, and the mind-body movement. Indeed, her visionary work shaped history – for good and, inadvertently, for evil. Before there was Bessel van der Kolk, there was Candace Pert, the Mother of the Mind-Body Revolution. Her story forms a launchpad to discuss the most pressing issues plaguing science and healthcare today. Pert played pivotal roles in major movements in both science and politics. Namely, she: Discovered the opiate receptor (the mechanism by which opioids function in the brain), launching the opioid crisis. Proved the mind-body link, launching the field of integrative or functional medicine. Created Peptide T, the underground AIDS drug featured in the film Dallas Buyers Club, and then went rogue, becoming a linchpin in the black market for her drug. Pert was sabotaged by mentors and colleagues keen to profit from her brilliance. But she too became tainted, believing that her noble ends would justify devious means. Like a mythic hero, she succumbed to a fatal flaw, and her greatest strengths—singularity of purpose and blind faith in her own virtuosity—would prove to be her undoing. CANDACE PERT is a great read for anyone interested in integrative health, mind-body awareness, medical ethics, the bureaucracy of a toxic healthcare system, and a flawed genius whose scandals and breakthroughs shaped history. &“Exemplary research, balanced accounts and deeply evocative prose... a truly insightful narrative on what it can mean to be a woman at the cutting edge of science.&” – The Wall Street Journal &“Riveting biography… nuanced portrait…Readers will be engrossed.&” – Publisher's Weekly &“There is a revolution taking form that is significantly influencing how the Western medical community views health and disease. Candace Pert&’s contribution to this revolution is undeniable.&” – Deepak Chopra &“Ryckman&’s writing is life-like, suspenseful, and creates a roller coaster ride of stakes and unexpected discovery&” – Dr. Lisa Miller, New York Times bestselling author of The Spiritual Child and The Awakened Brain
Candid Creatures: How Camera Traps Reveal the Mysteries of Nature
by Roland KaysA riveting collection of photographs that captures wild animals in their native habitats.In Candid Creatures, the first major book to reveal the secret lives of animals through motion-sensitive game cameras, biologist Roland Kays has assembled over 600 remarkable photographs. Drawing from archives of millions of color and night-vision photographs collected by hundreds of researchers, Kays has selected images that show the unique perspectives of wildlife from throughout the world. Using these photos, he tells the stories of scientific discoveries that camera traps have enabled, such as living proof of species thought to have been extinct and details of predator-prey interactions.Each image captures a moment frozen in the camera’s flash as animals move through their wild habitats. Kays also discusses how scientists use camera traps to address conservation issues, creating solutions that allow humans and wild animals to coexist. More than just a collection of amazing animal pictures, the book’s text, maps, and illustrations work together to describe the latest findings in the fast-moving field of wildlife research. Candid Creatures is a testament to how the explosion of game cameras around the world has revolutionized the study of animal ecology. The powerful combination of pictures and stories of discovery will fascinate anyone interested in science, nature, wildlife biology, or photography.
Candida Adherence to Epithelial Cells
by Mahmoud A. GhannoumThis is the first book ever to be published on this topic! Comprehensively packed with up-to-date research information, this volume is written with both the beginner and the established research expert in mind. Complemented with tables, line drawings, and photographs, this resource provides background material which allows the reader to become familiar with Candida albicans and its relation to its host. This unique work places particular emphasis on the effect of therapeutic agents on adherence and adherence blockage in the control of Candidosis. The goal of these studies is to be of practical value in the control and prevention of Candida infections. This book is of specific interest to all who are involved (at any level) with microbiology, infectious diseases, medical and veterinary mycology, and chemotherapy.
Candida Albicans: Methods and Protocols (Methods in Molecular Biology #499)
by Richard A. Calderone Ronald L. CihlarOver the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have come as the result of newly available genome sequences of pathogens such as candida albicans and other model fungi. In Candida Albicans: Methods and Protocols, expert researchers explore these exciting new insights, focusing on the study of medically important fungi and Candida spp in particular. Chapters examine critical aspects of molecular methods, providing information on reporter gene assays, transformation, gene expression in vivo, and methods for large-scale gene disruption. At the same time, the work includes in-depth descriptions of disease models of candidiasis, facts about strain identification, and guidelines on the preparation of samples for proteomic investigations and tandem affinity purification. Composed in the highly successful "Methods in Molecular BiologyTM" series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting edge, Candida Albicans: Methods and Protocols is an invaluable source of methods for investigators in the exhilarating fields of medical and molecular mycology.
Candida Species: Methods and Protocols (Methods in Molecular Biology #2542)
by Richard CalderoneThis updated volume explores Candida and candidiasis methods, useful to a wide variety of Candida scientists including those new to the field. Beginning with a section on the Candida genome, the book continues by covering techniques for antifungal discovery and studying resistance, pathogenesis and virulence, communities, as well as immunity. Biofilm protocols are also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Candida Species: Methods and Protocols, Second Edition serves as an ideal guide for researchers working to further our understanding of this family of infective fungi.
Candida albicans: Cellular And Molecular Biology
by Rajendra PrasadThis book on Candida albicans and similar pathogens provides a timely overview of the groundbreaking discoveries made in the areas of drug resistance, host–pathogen interactions, virulence, host immune system modulation, etc., in the last two decades. This comprehensive 2nd Edition includes chapters on fungal infections, hyphal morphogenesis, molecular mechanisms of antifungal resistance, antifungal agents, multidrug transporters, virulence mechanisms in Candida albicans, host–pathogen interactions, the cell wall, fungal biofilms, lipids and antifungal resistance, signaling mechanisms and last but not the least host-immune responses. As such, it offers an ideal reference guide for mycologists, researchers, pharmacists, clinicians, and undergraduate students engaged or interested in fungal research. It will also benefit clinicians, who are required to keep abreast of the current state of research on antifungal drug resistance and antifungal development.
Candida auris: Methods and Protocols (Methods in Molecular Biology #2517)
by Alexander LorenzThis volume covers the latest experimental protocols used by researchers to study the recently emerged fungal pathogen of humans, Candida auris, and also explores the pathogen’s antifungal resistance, virulence, and pathogenicity. The chapters in this book cover topics such as the identification of C. auris in clinic samples by PCR and mass spectrometry; molecular typing to identify clade affiliation; genetic manipulation; genome analysis by bioinformatics; and phenotypic characterization using various biochemical, mass spectrometry, microscopy, and flow cytometry approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Candida auris: Methods and Protocols is a valuable resource for researchers interested in learning more about this developing field.
Candy Experiments (Candy Experiments Ser. #1)
by Loralee LeavittCandy is more than a sugary snack. With candy, you can become a scientific detective. You can test candy for secret ingredients, peel the skin off candy corn, or float an &“m&” from M&M&’s. You can spread candy dyes into rainbows, or pour rainbow layers of colored water. You'll learn how to turn candy into crystals, sink marshmallows, float taffy, or send soda spouting skyward. You can even make your own lightning.Candy Experiments teaches kids a new use for their candy. As children try eye-popping experiments, such as growing enormous gummy worms and turning cotton candy into slime, they&’ll also be learning science. Best of all, they&’ll willingly pour their candy down the drain.Candy Experiments contains 70 science experiments, 29 of which have never been previously published. Chapter themes include secret ingredients, blow it up, sink and float, squash it, and other fun experiments about color, density, and heat. The book is written for children between the ages of 7 and 10, though older and younger ages will enjoy it as well. Each experiment includes basic explanations of the relevant science, such as how cotton candy sucks up water because of capillary action, how Pixy Stix cool water because of an endothermic reaction, and how gummy worms grow enormous because of the water-entangling properties.
Cane-based Biofuels And Bioproducts
by Sagadevan MundreeSugarcane has garnered much interest for its potential as a viable renewable energy crop. While the use of sugar juice for ethanol production has been in practice for years, a new focus on using the fibrous co-product known as bagasse for producing renewable fuels and bio-based chemicals is growing in interest. The success of these efforts, and the development of new varieties of energy canes, could greatly increase the use of sugarcane and sugarcane biomass for fuels while enhancing industry sustainability and competitiveness. Sugarcane-Based Biofuels and Bioproducts examines the development of a suite of established and developing biofuels and other renewable products derived from sugarcane and sugarcane-based co-products, such as bagasse. Chapters provide broad-ranging coverage of sugarcane biology, biotechnological advances, and breakthroughs in production and processing techniques. This text brings together essential information regarding the development and utilization of new fuels and bioproducts derived from sugarcane. Authored by experts in the field, Sugarcane-Based Biofuels and Bioproducts is an invaluable resource for researchers studying biofuels, sugarcane, and plant biotechnology as well as sugar and biofuels industry personnel.
Canine Confidential: Why Dogs Do What They Do
by Marc BekoffGet to know your best friend better: “Everyone who owns a dog, breeds or trains dogs, or works with dogs should read this informative book.” —Library JournalJust think about the different behaviors you see at a dog park. We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand?Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, Canine Confidential not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives better. Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions and trainers we must recognize them as the unique, complex individuals they are—so we can keep them as happy and healthy as possible.“Bekoff shares his own studies and others’ research, along with real-life stories, in a winning tone.” —Booklist
Canine Epilepsy: An Owner's Guide to Living With and Without Seizures
by Caroline D. LevinThis canine Epilepsy guide helps you to not only understand what this disease entails but also the kinds of things that can help your dog gain control- including medical issues or treatments that can make the situation worse. A must read for anyone dealing with seizures in their dog.
Canine Ergonomics: The Science of Working Dogs
by William S. HeltonSince Canis lupus familiaris first shared a fire with man more than 15,000 years ago, dogs have been trusted and valued coworkers. Yet the relatively new field of canine ergonomics is just beginning to unravel the secrets of this collaboration. As with many new fields, the literature on working dogs is scattered across several non-overlapping disci
Canine Olfaction Science and Law: Advances in Forensic Science, Medicine, Conservation, and Environmental Remediation
by Tadeusz Jezierski John Ensminger L. E. PapetThe value of the canine nose is well-documented, and working dogs are being utilized for their olfactory skills in an increasing number of fields. Not only are dogs used by police, security, and the military, but they are also now used in forensic science, in medical detection of disease, in calculating population trends of endangered species and e
Canine and Feline Anesthesia and Co-Existing Disease
by Lindsey B.C. Snyder Rebecca A. JohnsonCanine and Feline Anesthesia and Co-Existing Disease is the first book to draw together clinically relevant information on the anesthetic management of dogs and cats with existing disease conditions. Providing a detailed reference on avoiding and managing complications resulting from concurrent disease, the book offers a ready reference for handling anesthesia in patients with common presenting diseases. Organized by body system, Canine and Feline Anesthesia and Co-Existing Disease is designed to allow the reader to quickly find and apply advice for anesthetizing patients with specific conditions. Each chapter presents in-depth, practical information on the special considerations before, during, and after sedation and anesthesia of a patient with a given disease. Canine and Feline Anesthesia and Co-Existing Disease is a useful reference for general practitioners, veterinary students, specialists in a variety of areas, and veterinary anesthesiologists alike.
Cann's Principles Of Molecular Virology
by Edward P. RybickiCann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work. It discusses the interactions which control the structure of virus particles, the ways viruses infect cells, how viruses replicate themselves, and the consequences and pathogenesis of virus infection for host organisms. This fully updated edition also reflects advances made in the field and includes new content on phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses. With the addition of ancillary resources, Principles of Molecular Virology, Seventh Edition is an essential foundational reference for academics, graduate students, and advance undergraduates in virology, molecular biology, and microbiology as well as researchers entering virology, infectious disease, and immunology research.
Cannabinoids
by Vincenzo Di MarzoThe 21st century will witness the unprecedented marketing of therapeutic drugs developed from cannabinoids and the endocannabinoid system. Cannabinoids is a timely volume, which represents a comprehensive review of the most important issues in cannabinoid research as well as those of most likely therapeutic relevance. For the first time, the multi-faceted aspects of cannabinoid chemistry, biology and medicine are presented in one volume. Key topics of discussion: -major families of phytocannabinoids; -pharmacological activity of phytocannabinoids; -interactions of phytocannabinoids with their proposed molecular target; -components of the endocannabinoid system; -molecular mechanisms of the endocannabinoid system; -Physiological and pathological role of endocannabinoids; -industrial applications of studies on the cannabinoids; -therapeutic uses of agonists and antagonists of cannabinoids receptors. This book is a must for graduate and pre- and post-doctoral students in disciplines ranging from organic and natural product chemistry, pharmacology, biochemistry and medicine.
Cannabinoids and Neuropsychiatric Disorders (Advances in Experimental Medicine and Biology #1264)
by Jaime M. Monti S. R. Pandi-Perumal Eric Murillo-RodriguezThis volume highlights the recent advances in the understanding of the endocannabinoid system and the likely benefit from the therapeutic effects of cannabinoid treatment in a variety of health issues.Archeological evidence has shown that Cannabis has a long history of use for multiple purposes, including the treatment of medical conditions. The primary active constituent of the hemp plant Cannabis sativa, delta 9-tetrahydrocannabinol (Δ9-THC), causes euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory, among other effects. Despite these undesirable effects, signaling is mostly inhibitory and suggests a putative role for cannabinoids as therapeutic agents by managing several diseases where inhibition of neurotransmitter release would be beneficial. The themes of this book have been edited and written by world-leaders in the field, The contents of the volume aims at readers from a range of academic and professional disciplines, such as biomedicine, several areas of biology, neurology, clinical medicine and pharmacy.
Cannabinoids and Sleep: Molecular, Functional and Clinical Aspects (Advances in Experimental Medicine and Biology #1297)
by Jaime M. Monti S. R. Pandi-Perumal Eric Murillo-RodríguezResearch on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.
Cannabinoids and the Brain
by Linda A. ParkerThe cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic uses. Parker describes the discovery of tetrahydocannbinol (THC), the main psychoactive component of cannabis, and the further discovery of cannabinoid receptors in the brain. She explains that the brain produces chemicals similar to THC, which act on the same receptors as THC, and shows that the endocannabinoid system is involved in all aspects of brain functioning. Parker reports that cannabis contains not only the psychoactive compound THC, but also other compounds of potential therapeutic benefit, and that one of them, cannabidiol (CBD), shows promise for the treatment of pain, anxiety, and epilepsy. Parker reviews the evidence on cannabinoids and anxiety, depression, mood, sleep, schizophrenia, learning and memory, addiction, sex, appetite and obesity, chemotherapy-induced nausea, epilepsy, and such neurodegenerative disorders as multiple sclerosis and Alzheimer's Disease. Each chapter also links the scientific evidence to historical and anecdotal reports of the medicinal use of cannabis. As debate about the medical use of marijuana continues, Parker's balanced and objective review of the fundamental science and potential therapeutic effects of cannabis is especially timely.
Cannabinoids and the Brain (The\mit Press Ser.)
by Linda A. ParkerA review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic use.The cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic uses.Parker describes the discovery of tetrahydocannbinol (THC), the main psychoactive component of cannabis, and the further discovery of cannabinoid receptors in the brain. She explains that the brain produces chemicals similar to THC, which act on the same receptors as THC, and shows that the endocannabinoid system is involved in all aspects of brain functioning. Parker reports that cannabis contains not only the psychoactive compound THC, but also other compounds of potential therapeutic benefit, and that one of them, cannabidiol (CBD), shows promise for the treatment of pain, anxiety, and epilepsy. Parker reviews the evidence on cannabinoids and anxiety, depression, mood, sleep, schizophrenia, learning and memory, addiction, sex, appetite and obesity, chemotherapy-induced nausea, epilepsy, and such neurodegenerative disorders as multiple sclerosis and Alzheimer's Disease. Each chapter also links the scientific evidence to historical and anecdotal reports of the medicinal use of cannabis.As debate about the medical use of marijuana continues, Parker's balanced and objective review of the fundamental science and potential therapeutic effects of cannabis is especially timely.
Cannabis (seeing through the smoke): The New Science of Cannabis and Your Health
by Professor David NuttThe definitive guide to Cannabis and your health, from world-renowned Professor of Neuropsychopharmacology, David Nutt.Underpinned by his two-year research trial in partnership with the Royal College of Psychiatrists, involving up to 20,000 patients, which will create Europe's largest body of evidence on the plant's medicinal qualities - Professor David Nutt and his team of scientists will break the mould on the way we use Cannabis for our health in the future. In David's first ground-breaking book on the subject, he will cover its impact of all areas of the body and the brain and its effective use for treatment of illness from chronic pain, epilepsy, multiple sclerosis and PTSD, to anxiety and depression. This is the essential knowledge that cuts through the noise and give us evidence-based information that will change people's lives.(P)2021 Hodder & Stoughton Limited
Cannabis (seeing through the smoke): The New Science of Cannabis and Your Health
by Professor David NuttTHE DEFINITIVE GUIDE TO CANNABIS AND YOUR HEALTHUnderpinned by his two-year research trial in partnership with the Royal College of Psychiatrists, involving up to 20,000 patients, which will create Europe's largest body of evidence on the plant's medicinal qualities - Professor David Nutt and his team of scientists will break the mould on the way we use Cannabis for our health in the future. In David's first ground-breaking book on the subject, he will cover its impact of all areas of the body and the brain and its effective use for treatment of illness from chronic pain, epilepsy, multiple sclerosis and PTSD, to anxiety and depression. This is the essential knowledge that cuts through the noise and give us evidence-based information that will change people's lives.