- Table View
- List View
Carcinoma of the Larynx and Hypopharynx
by Sudhir Bahadur Alok Thakar Bidhu K. MohantiCarcinomas of the larynx and hypopharynx present unique challenges when it comes to their assessment and management. Management involves the essential dilemma of optimizing cure rates while also ensuring that potential disability due to compromised airway, voice and swallowing is minimized. Treatment decisions involve careful disease assessment, judicious multispecialty decision-making, and subsequent meticulous implementation of the selected treatment modalities.The critical nature of each of these steps has led to dramatic advances in assessment techniques (radiology, endoscopy and photography, stroboscopy, narrow band imaging, contact endoscopy) and also in treatment methods (radiation therapy, combined concurrent chemo-radiation, combined sequential chemo-radiation, trans-oral CO2 laser and robotic surgery, partial laryngectomy, total laryngectomy, extended total laryngectomy). As such, treatment decisions have become increasingly complex with the twin objectives of maximizing cure as well as function preservation and are based on tumor stage, tumor location, systemic co-morbidities, nutritional status, patient priorities, and social and economic factors. This multidisciplinary book has been written by a team of editors with considerable experience and expertise in these critical areas and a deep understanding of teamwork and the strengths and limitations of individual technologies and treatments. It presents a homogeneous and unbiased view that is applicable to all specialties involved in the care of larynx and hypopharynx cancers.
Cardamom: The Genus Elettaria (Medicinal And Aromatic Plants - Industrial Profiles Ser. #Vol. 30)
by P. N. Ravindran K. J. MadhusoodananCardamom otherwise known as Malabar cardamom, true cardamom or small cardamom second only to pepper in its importance during the Renaissance period, is often qualified as the Queen of Spices because of its very pleasant aroma and taste. The Western Ghat forest of the Malabar coast, India, is the center of origin and diversity for cardamom and it mi
Cardboard Box Engineering: Cool, Inventive Projects for Tinkerers, Makers & Future Scientists
by Jonathan AdolphCardboard is everywhere! For creative kids aged 9 to 14, it&’s the perfect eco-friendly building material, and Cardboard Box Engineering is the perfect guide to get them started on inventive tinkering. A working kaleidoscope, a marble roller coaster, a robotic hand, and a wind-powered tractor with cardboard gears are just some of the ingenious projects developed by Jonathan Adolph, author of the best-selling Mason Jar Science. Working with simple household tools, kids can follow the step-by-step photographic instructions to exercise their design smarts, expand their 3-D thinking, and learn the basics of physics and engineering with activities that have real-life applications.
Cardiac Adaptations: Molecular Mechanisms (Advances in Biochemistry in Health and Disease #4)
by Bohuslav Ostadal Naranjan S. DhallaThis book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.
Cardiac CT Imaging: Diagnosis of Cardiovascular Disease
by Matthew J. Budoff Jerold S. ShinbaneCT is an accurate technique for assessing cardiac structure and function, but advances in computing power and scanning technology have resulted in increased popularity. It is useful in evaluating the myocardium, coronary arteries, pulmonary veins, thoracic aorta, pericardium, and cardiac masses; because of this and the speed at which scans can be performed, CT is even more attractive as a cost-effective and integral part of patient evaluation. This book collates all the current knowledge of cardiac CT and presents it in a clinically relevant and practical format appropriate for both cardiologists and radiologists. The images have been supplied by an experienced set of contributing authors and represent the full spectrum of cardiac CT. As increasing numbers have access to cardiac CT scanners, this book provides all the relevant information on this modality. This is an extensive update of the previous edition bringing the reader up-to-date with the immense amount of updated content in the discipline.
Cardiac Cytoarchitecture: How to Maintain a Working Heart
by Elisabeth EhlerThis book presents a collection of expert reviews on different subcellular compartments of the cardiomyocyte, addressing fundamental questions such as how these compartments are assembled during development, how they are changed in and by disease and which signaling pathways have been implicated in these processes so far. As such, it offers the first overview of the cell biology of heart disease of its kind, addressing the needs of cell biology students specializing in vascular and cardiac biology, as well as those of cardiologists and researchers in the field of cell biology.
Cardiac Electrosonography
by David Leibowitz Eyal Herzog Yair ElitzurThis book focuses on a new clinical algorithmic approach to acute patient care based on the combination of electrocardiography (ECG) and echocardiography performance and interpretation, now renamed: ECG-sonography or electrosonography. The combination of these two basic skills improves patient management by healthcare providers in the acute setting. ECG is one of the oldest diagnostic tools in evaluating patients with cardiovascular symptoms and multiple and complex criteria for its interpretation have been developed over the past decades. The use of point of care ultrasound based on handheld echocardiography has recently emerged as an important clinical tool, particularly in the emergency department (ED) and intensive care unit. These studies are mainly performed by non-cardiologists including intensivists and ED physicians in addition to the physical exam and standard diagnostic tests such as the chest X-ray and laboratory tests to evaluate patients quickly and efficiently.Cardiac Electrosonography provides a new algorithmic approach to ECG interpretation and a simple tutorial of echocardiography performance and interpretation with a major focus on handheld echocardiography. It includes representative cases of patients presenting to the ED with a specific, acute cardiovascular symptom and demonstrates appropriate use of both ECG and echocardiography to improve patient management and outcome. It therefore represents an essential guide to this hybrid procedure for all practicing and trainee cardiologists and all healthcare professionals who manage these patients.
Cardiac Energy Metabolism in Health and Disease (Advances in Biochemistry in Health and Disease #11)
by Naranjan S. Dhalla Gary D. LopaschukThe heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.
Cardiac Gene Expression: Methods and Protocols (Methods in Molecular Biology #366)
by Jun Zhang Gregg RokoshThis book presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function. The concluding section of the book highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.
Cardiac Gene Therapy: Methods and Protocols (Methods in Molecular Biology #2573)
by Kiyotake IshikawaThis second edition volume expands on the previous edition with updated techniques and discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Cardiac Gene Therapy: Methods and Protocols, Second Edition is a valuable tool for researchers in cardiology who are conducting gene therapy research. This book will lead to further advancements and successful clinical translations in the field.
Cardiac Imaging in Electrophysiology
by Frank E. Rademakers Jagmeet Singh Angelo AuricchioCardiac arrhythmias are a major cause of death (7 million cases annually worldwide; 400,000 in the U.S. alone) and disability. Yet, a noninvasive imaging modality to identify patients at risk, provide accurate diagnosis and guide therapy is not yet available in clinical practice. Nevertheless, there are various applications of electrophysiologic imaging in humans from ECG/CT reconstructions, MRI to tissue Doppler investigations that provide supplimentary diagnostic data to the cardiologist. EP laboratories are experiencing an increase in volume, for both diagnostic and interventional electrophysiology studies, including mapping, ablation, and pacemaker implants. The equipment requirements for these procedures are stringent, include positioning capabilities, and dose management. This book is designed to review all of the current imaging methodologies that assist in diagnosis within the electrophysiology department.
Cardiac MRI Certification Exam: 150 Questions and Review
by Scott E. Janus Sadeer G. Al-KindiThis book serves as a board review book for cardiovascular magnetic resonance imaging (CMR). CMR is now an essential part of cardiology training and there is yet to be a dedicated review book for the topic. This book seeks to fill that gap. With 150 questions and answers, this review provides a comprehensive and easily readable educational tool for trainees and cardiologists. The book is divided into 10 chapters, each about 15 questions. The multiple-choice questions cover topics according to the board examinations blueprints, including a wide spectrum of cardiac pathologies and concepts. Answers are supported by concise summaries and explanations to aid understanding. Each question also includes links to the latest resources and literature. This book helps readers not only prepare for CMR boards, but provides a good review of anatomy and pathology for cardiac imagers.
Cardiac Magnetic Resonance Atlas: 101 Clinical Cases
by Yasmin Rustamova Massimo LombardiThis book presents the main cardiac pathologies, providing a helpful guide featuring clinical cases and electronic supplementary material. There are several systematic books on cardiac magnetic resonance, which approach the different pathologies and related pathophysiology in a general manner, and these are useful for readers at an early stage in their medical careers. However, when it comes to individual patients (during the acquisition of images and reporting activities) there is no book providing operative protocols or systematic descriptions of details to look for. In the eight chapters (Cardiomyopathies, Myocarditis, Ischemic Heart Disease, Valvular Heart Diseases, Cardiac Masses, Pericardial Diseases, Congenital Heart Disease, and Miscellanea), the individual pathology is illustrated with a clinical case.The cases are divided into four sections: An introduction with a short medical history and the purpose of the diagnostic CMRA detailed CMR acquisition protocolCMR images, indicating purpose, method, analysis and meaning of the image, as well as videos.Concluding paragraph with the final diagnosis reached on the basis of the findings obtained in each image This book, collecting one hundred one clinical cases covering a broad spectrum of cardiac diseases, is an invaluable tool for radiologists and cardiologists.
Cardiac Mechanobiology in Physiology and Disease (Cardiac and Vascular Biology #9)
by Markus Hecker Dirk J. DunckerThis book presents the latest findings in the field of cardiac mechanobiology in health and disease.Cardiac mechanobiology provides knowledge of all aspects of mechanobiology of the heart. Cardiomyogenesis is discussed as well as the mechanobiology of cardiac remodeling and regeneration. The molecular mechanisms of mechanoperception and mechanotransduction in cardiomyocytes are explained, as well as stretch induced differentiation of cardiomyocytes derived from induced pluripotent stem cells. This volume of the series Cardiac and Vascular Biology complements the volume Vascular Mechanobiology in Physiology and Disease (volume 8) published in this series. The book is aimed at clinicians as well as researchers in cardiovascular biology, bioengineering and biophysics, and also represents an educational resource for young researchers and students in these fields.
Cardiac Pathology: A Guide to Current Practice
by S. Kim SuvarnaThis updated second edition provides a comprehensive overview of cardiac pathology. Clear illustrations of the common styles of dissection are provided along with the normal anatomy and histology. The chapters cover autopsy heart examination, ischemic heart disease, myocarditis, sudden death, valvular disease, transplant pathology, cardiomyopathy, cardiac neoplasia and congenital heart disease with a clear analysis of diagnostic criteria (macroscopic, microscopic and genetic) for both common cardiac diseases and those of less common types. The text is accompanied by high quality macroscopic and microscopic images and references to other specialty data sources. Cardiac Pathology: A Guide to Current Practice is aimed at established pathologists and trainees, as well as any clinician with an interest in cardiac disease. It will be of value to those working in cardiac surgery, cardiology and those in the autopsy/forensic fields.
Cardiac Pathology: A Guide to Current Practice
by Simon SuvarnaCardiac disorders are an exciting area of classic pathology and recently defined disease. Cardiac Pathology: A Guide to Current Practice discusses the various disorders and also provides a backdrop of developmental embryology, diagnostic imaging and current therapeutics. Cardiac Pathology: A Guide to Current Practice aims to deliver in bench-book format a comprehensive overview of cardiac pathology that is relevant to those practicing in surgical pathology and autopsy arenas. Clear illustrations of the common styles of dissection are provided along with the normal anatomy and histology. Chapters cover the approach to the autopsy heart, ischemic heart disease, myocarditis, sudden death, valvular disease, transplant pathology, cardiomyopathy, cardiac neoplasia and congenital heart disease with a clear analysis of diagnostic criteria (macroscopic, microscopic and genetic) for both common cardiac diseases and those of rare format. The text is accompanied by high-quality macroscopic and microscopic images and references to other in-depth specialty data sources. Although aimed in particular at pathologists, Cardiac Pathology: A Guide to Current Practice should also be of value to cardiologists, cardiothoracic surgeons and other professions allied to medicine.
Cardiac Regeneration (Cardiac and Vascular Biology #4)
by Masaki Ieda Wolfram-Hubertus ZimmermannThis Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Cardiac Regeneration: Methods and Protocols (Methods in Molecular Biology #2158)
by Kenneth D. Poss Bernhard KühnThis detailed book addresses major goals of regenerative medicine and the cardiovascular research community with techniques to replenish lost cardiomyocytes, avoid scar-associated pathology, and improve myocardial infarction (MI) outcomes. The collection begins with a section on cardiac injury models, including zebrafish, neonatal and adult mice, and pigs, and continues with sections covering culturing cardiomyocytes from different species as well as methods for labeling or manipulation of cardiac tissue for the purpose of answering questions in regeneration. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Regeneration: Methods and Protocols provides the latest models and methods used in the field of heart regeneration, designed for researchers interested in establishing these assays in their laboratories to reproduce or extend findings, and for familiarizing themselves with the field if it is new to them.
Cardiac Remodeling: Molecular Mechanisms (Advances in Biochemistry in Health and Disease #5)
by Naranjan S. Dhalla Bodh I. JugduttThe main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside.
Cardiac Tissue Engineering: Methods and Protocols (Methods in Molecular Biology #1181)
by Milica Radisic Lauren D. Black IIICardiac Tissue Engineering: Methods and Protocols presents a collection of protocols on cardiac tissue engineering from pioneering and leading researchers around the globe. These include methods and protocols for cell preparation, biomaterial preparation, cell seeding, and cultivation in various systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols highlights the major techniques, both experimental and computational, for the study of cardiovascular tissue engineering.
Cardiac Tissue Engineering: Methods and Protocols (Methods in Molecular Biology #2485)
by Lauren D. Black III Kareen L. K. CoulombeThis detailed volume presents an updated collection of state-of-the-art protocols in cardiac tissue engineering. These protocols demonstrate advancements in cell sourcing, assembly, and use of engineered cardiac tissues, imaging and diagnostics, as well as therapeutic applications. New animal models, biomaterials, and quantitative analyses are described for broad adoption. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols, Second Edition serves as an ideal resource for inspiring the advancement of cardiotoxicity assessment, drug discovery, and heart repair and regeneration in order to accelerate heart health improvement around the globe.
Cardio-Respiratory Control in Vertebrates: Comparative and Evolutionary Aspects
by Mogens L. Glass Stephen C. WoodThe focus of this book is the evolution of cardiovascular and respiratory control in vertebrates. Life originated in water, which has constantly changing temperatures and O2 levels. Fish gills can extract up to 80% of their inspired O2, because they have a countercurrent bloodstream. Oxygen sensors have been found within the gill arches of ray-finned fish such as carp and trout, and these O2 sensors screen the inspired water and the capillary blood. Very likely, land vertebrates and the lungfish arose as a sister group, and both possess real lungs. Lungfish include 6 species, inhabiting shallow lakes or rivers, whereas the second ramification includes all the land vertebrates. A possible ancestor to the lungfish and land vertebrates has been discovered in China, and this fossil (Styloichthys) bridges a gap. Living 417 million years ago, it could represent one of the last ramifications before the common ancestor to the lungfish and land vertebrates. In addition, rather constant atmospheric O2 levels permit a joint acid-base regulation by the lung and the kidney. Likewise, lungfish and land vertebrates share a central control of pulmonary ventilation, while the peripheral receptor contribution to acid-base regulation is minor.
Cardiology Procedures: A Clinical Primer
by Robert C. Hendel Carey KimmelstielThis extensively revised edition is a single compact reference that describes a wide variety of diagnostic and therapeutic procedures performed by cardiologists. The focus is on the clinical application of these procedures with descriptions of their technical aspects, as well as contraindications and potential complications. The book provides detailed instruction on the interpretation of clinical data generated during these procedures and includes case presentations to illustrate how they are utilized in clinical practice.Cardiology Procedures: A Clinical Primer contains distilled clinical information and data important to those involved in the clinical care of cardiac patients. Comprising practical material designed to help in learning the diagnostic and therapeutic cardiology procedures performed in clinical practice, it will also be useful for trainees and practitioners in related disciplines.
Cardiology Science and Technology
by Dhanjoo N. GhistaCardiology Science and Technology comprehensively deals with the science and biomedical engineering formulations of cardiology. As a textbook, it addresses the teaching, research, and clinical aspects of cardiovascular medical engineering and computational cardiology. The books consists of two sections. The first section deals with left ventricular
Cardiomyocytes in Health and Disease
by Chandrasekharan C. KarthaThis book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon.