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Cis/Transgene Optimization: Systematic Discovery Of Novel Gene Expression Elements Using Bioinformatics And Computational Biology Approaches (Springerbriefs In Systems Biology Ser.)
by Saeid Kadkhodaei Farahnaz Sadat Golestan Hashemi Morvarid Akhavan Rezaei Sahar Abbasiliasi Joo Shun Tan Hamid Rajabi Memari Faruku Bande Ali Baradaran Mahdi Moradpour Arbakariya B. AriffThis book is a practical review which focuses on computational analysis and on in silico approaches towards the systematic discovery of various key functional gene expression elements in microalgae as a model. So far, in this regard very little information is available. Efficient stepwise procedures for analysing the matrix attachment regions (MARs) are outlined, as well as for translation initiation sites (TIS), signal peptide (SP) sequences, gene optimization and transformation systems. These outlines can be efficiently deployed as practical models for the systematic discovery of key expression elements and for the optimization of cis/transgenes in other micro/organisms. The first chapter is an introduction on the key gene expression elements analysed in this book, including scaffold/matrix attachment regions, translation initiation sites, signal peptides as well as gene optimization. Chapter 2 focuses on systematic strategies and computational approaches toward in silico analysis of each factor. The analyses outcomes is assessed individually in chapter 3 followed by developing the specific conceptual models for each element in Chapter 4. The concluding remarks are discussed in Chapter 5. This work is of interest to computational and experimental biologists interested in transcriptional regulation analysis as well as to researchers and scientists who wish to consider the use of bioinformatics and computational biology in design, analysis, or regulatory reviews of key gene expression elements for the production of recombinant proteins experiments.
Cisgenic Crops: Potential and Prospects (Concepts and Strategies in Plant Sciences)
by Chittaranjan Kole Anurag ChaurasiaThis book is the first attempt for in-depth compilation of current knowledge on cisgenic crops and their potential prospects as a sustainable substitute for the controversial genetically modified crops. Innovative methodologies for the development of cisgenic crops for disease resistance, improved nutritional contents, suitability for organic farming, survival under climate change, and their role in conservation of plant genetic resources have been highlighted. Combined with molecular markers and genome editing, an advanced approach for crop improvement is reported. The book has 14 chapters authored by globally leading experts on the subject. This book is useful to the students, teachers, researchers and policy planners working across the disciplines of classical plant breeding up to the recent genetically modified and genome edited crops.
Cisgenic Crops: Safety, Legal and Social Issues (Concepts and Strategies in Plant Sciences)
by Chittaranjan Kole Anurag ChaurasiaThis book is the first comprehensive compilation of existing knowledge on the impact of cisgenic crops on biodiversity, environment, and ecosystem. Strategies to create and access cisgenic crops, potential risks assessment, and legal implications across the globe (European Union, North and South Americas, Africa, and Asia) are enumerated. Ethics, economics, safety, social concerns, and consumer acceptance of cisgenic foods are deliberated. Policy paradigm and ways to overcome GM regulations through cisgenic crops are highlighted. The book has 12 chapters authored by internationally leading experts on the subject. This book will be useful especially for the policy makers and GMO regulators, while the students, teachers, and researchers from across the globe will be equally benefited.
Cisgenics and Transgenics: Strategies for Sustainable Crop Development and Food Security
by Bhupendra KoulThis book presents up-to-date information on various vector-less/direct (physical, chemical) and vector-mediated/indirect (Agrobacterium-mediated) plant transformation techniques. It summarizes various strategies that facilitate a gene from lower organism to be expressed in higher plants and also in silico designing of synthetic gene for higher expression. It also highlights the importance of strong promoters to drive the expression of transgene(s). This book encompasses the advantages and drawbacks of cisgenesis and transgenesis, their implications towards sustainable crop improvement, and their future prospects. The importance, limitations, challenges, recent developments, and future prospects of molecular pharming is also discussed. The book concludes with a chapter that summarizes the major contribution of GM-crops towards global food security and economy, advances in genome editing for crop improvement, challenges and risk associated with the release of GM-crops, and the future of GM technology. This book is meant for students and researchers in the field of life sciences, food science, and agriculture.
Citation Analysis and Dynamics of Citation Networks (SpringerBriefs in Complexity)
by Michael GolosovskyThis book deals with the science of science by applying network science methods to citation networks and uniquely presents a physics-inspired model of citation dynamics. This stochastic model of citation dynamics is based on a well-known copying or recursive search mechanism. The measurements covered in this text yield parameters of the model and reveal that citation dynamics of scientific papers is not linear, as was previously assumed. This nonlinearity has far-reaching consequences including non-stationary citation distributions, diverging citation trajectories of similar papers, and runaways or "immortal papers" with an infinite citation lifespan. The author shows us that nonlinear stochastic models of citation dynamics can be the basis for a quantitative probabilistic prediction of citation dynamics of individual papers and of the overall journal impact factor. This book appeals to students and researchers from differing subject areas working in network science and bibliometrics.
Cities In Space (Endless Frontier Volume #3)
by Jerry Pournelle John F. CarrSomeday in the near future, our pioneer spirit will take us to the stars. But how will we organize our colonies? What unforeseen dangers will we face? And who will be chosen to go? Now today's masters of science fiction offer some startling possibilities. Introduction: The endless frontier by Jerry Pournelle Consort by Jerry Pournelle The Free Agent by Michael Cassutt What are these Lagrange points anyway by Doug Beason The Christmas Count by Henry Melton The Lagrange League Stationary Habitats by William John Watkins When Silver Plums Fall by Bruce Boston High Flight by John Gillespie MaGee Jr. Lifeguard by Doug Beason New Worlds in Space by Norman Spinrad The Software Plague by John Park Blindsight by Robert Silverberg Access to Space, SSX by Jim Ransom Ghost Town by Chad Oliver Poppa Was a Catcher by Steven Gould In appreciation Robert A. Heinlein by Jerry Pournelle The Long Watch by Robert A. Heinlein
Cities and Climate Change (Routledge Studies in Physical Geography and Environment)
by Harriet Bulkeley Michelle BetsillClimate change is one of the most challenging issues of our time. As key sites in the production and management of emissions of greenhouse gases, cities will be crucial for the implementation of international agreements and national policies on climate change. This book provides a critical analysis of the role of cities in addressing climate change and the prospects for urban sustainability. Cities and Climate Change is the first in-depth analysis of the role of cities in addressing climate change. The book argues that key challenges concerning the resources and powers of local government, as well as conflicts between local goals for economic development and climate change mitigation, have restricted the level of local action on climate change. These findings have significant implications for the prospects of mitigating climate change and achieving urban sustainability. This book provides a valuable interdisciplinary analysis of these issues, and will appeal to students and researchers interested in sustainability at local and global scales.
Cities and Disasters
by Davia C. DowneyCities and Disasters presents interdisciplinary and multinational perspectives on emergency management policy, economic development, and the various factors that affect the recovery process after natural disasters strike urban areas. The book has three central themes: policy, urbanity, and the interplay of events after disasters that affect the pro
Cities and Mega Risks: COVID-19 and Climate Change
by Mohammad Aslam KhanThis book focuses on the emergence of COVID-19 and climate change as twin mega risks to cities of both developed and developing countries. The work analyses how the pandemic has transformed city functions, promoted remote working, and affected socializing, education and learning patterns, recreation, as well as shopping and entertainment. It discusses the lessons learned from these two Mega Risks, the evolution of urban patterns and functions in their wake, and provides visionary thinking for the improvement of cities from the experiences gained. The COVID-19 Pandemic and climate change are both posing serious threats to cities’ future. Together, they demand changes in the ways cities’ function and operate. The work presents a case for a better understanding of the twin mega risks, the magnitude of their impacts, the responses of cities in combating these issues, and planning strategies for preparing, mitigating and adapting to these and future risks. The book is designed to provide reliable resource materials for a wide audience such as planners, professional practitioners, scientists, students, teachers and researchers working in various fields including geography, environmental sciences, social sciences, policy and planning.
Cities and Mega-Cities: Problems and Solution Strategies (SpringerBriefs in Geography)
by Frederic R. SiegelThis book discusses existing and future global problems of physical, chemical, biological and societal origins faced by increasingly populated cities and mega-cities, and options to mitigate or eliminate them. In nine chapters, the book focuses on rehabilitation and redevelopment projects aimed at converting shantytowns/slums into well serviced neighborhoods via secure housing, clean piped water, adequate access to sanitation, and other amenities for good living conditions. Examples of rehabilitation (restore capacity, structures, efficiency) and redevelopment (redesign, rebuild, attract investment) are addressed in detail, as are the sources of major financing to support such projects and proposals. The final chapters also discuss problems faced by countries with contracting populations, and their viable solutions. The book will be of interest to academics, city planners, land-use planners, NGOs, and designers /architects specializing in urban development and redevelopment.
Cities and Nature (Routledge Critical Introductions to Urbanism and the City)
by John Rennie Short Lisa Benton-ShortCities and Nature connects environmental processes with social and political actions. The book reconnects science and social science to demonstrate how the city is part of the environment and how it is subject to environmental constraints and opportunities. This second edition has been extensively revised and updated with in-depth examination of theory and critical themes. Greater discussion is given to urbanization trends and megacities; the post-industrial city and global economic changes; developing cities and slums; urban political ecology; the role of the city in climate change; and sustainability. The book explores the historical relationship between cities and nature, contemporary challenges to this relationship, and attempts taken to create more sustainable cities. The historical context situates urban development and its impact on the environment, and in turn the environmental impact on people in cities. This provides a foundation from which to understand contemporary issues, such as urban political ecology, hazards and disasters, water quality and supply, air pollution and climate change. The book then considers sustainability and how it has been informed by different theoretical approaches. Issues of environmental justice and the role of gender and race are explored. The final chapter examines the ways in which cities are practicing sustainability, from light "greening" efforts such as planting trees, to more comprehensive sustainability plans that integrate the multiple dimensions of sustainability. The text contains case studies from around the globe, with many drawn from cities in the developing world, as well as reviews of recent research, updated and expanded further reading to highlight relevant films, websites and journal articles. This book is an asset to students and researchers in geography, environmental studies, urban studies and planning and sustainability.
Cities and Regions as Self-Organizing Systems: Models of Complexity (Environmental Problems And Social Dynamics Ser. #Vol. 1)
by Peter M. AllenA clear methodological and philosophical introduction to complexity theory as applied to urban and regional systems is given, together with a detailed series of modelling case studies compiled over the last couple of decades. Based on the new complex systems thinking, mathematical models are developed which attempt to simulate the evolution of towns, cities, and regions and the complicated co-evolutionary interaction there is both between and within them. The aim of these models is to help policy analysis and decision-making in urban and regional planning, energy policy, transport policy, and many other areas of service provision, infrastructure planning, and investment that are necessary for a successful society.
Cities as Anticipatory Systems (The Urban Book Series)
by Bruno Gandlgruber Salomón González-ArellanoThe theory of anticipation suggests that systems, both biological and social, can adapt and update based on predictive models. Cities, which can be seen as complex systems that are associated with innovation, are undergoing changes in response to current socio-ecological transitions. Therefore, cities can be viewed as anticipatory systems that may signal future transformations that arise in response to the challenges posed by these ongoing socio-ecological transitions. This book combines futures studies and anticipation theories with urban studies and theories of urban transition. Chapters address theoretical and empirical aspects of both fields and present case studies from a wide array of international perspectives. These diverse examples demonstrate how cities implement arrangements and strategies to allow their actors of all kinds to anticipate change. As such, contributions in this edited volume explore possible scenarios and proposals for strengthening anticipatory competences in urban areas and examine the potential consequences of these innovations in the cities of the future.
Cities of Tomorrow: Urban Resilience and Climate Change Preparedness (Urban Sustainability)
by Ali Cheshmehzangi Sushobhan Majumdar Shovan GhoshThis book takes a comprehensive and forward-looking approach to urban resilience and climate change preparedness. It combines theoretical insights, practical case studies and innovative strategies to address the complex challenges cities face in an era of rapid urbanisation and changing climate patterns. It presents a fresh and innovative approach to addressing the intertwined challenges of urban resilience and climate change preparedness. What sets this book apart is its emphasis on forward-looking strategies, multidisciplinary insights and a comprehensive exploration of cutting-edge technologies and collaborative approaches. This book is likely to be diverse, encompassing professionals, academics, researchers, policymakers, practitioners, students and individuals interested in the fields of urban planning, environmental science, sustainability, climate change adaptation and related disciplines. The book aims to appeal to both experts in the field and those new to the subject, providing a valuable resource for different audiences.
Cities of the Future: Challenges and Opportunities
by Asmaa Ibrahim Mady Mohamed Mohamed FekryThis book seeks to address the key challenges and opportunities of "future cities" embracing novel approaches and grounded technologies in pursuing a vision for smart, inclusive cities. The objective of this book is to discuss multiple areas at the local, national, and international levels and how these challenges can hinder the development objectives planned to be achieved by the cities of the future. The chapters featured in this collection were presented at the 6th Memaryat International Conference (MIC 2022), held at the Effat University, Jeddah. MIC’s objective is to build bridges between science, technology, and innovation, seen as the key levers of attaining the SDGs.This book provides the most innovative ideas presented at the conference to address the key manifestation of “future cities" to embrace novel approaches and grounded technologies in the pursue of a vision for smart inclusive cities. It thus represents a platform for diverse contributions from academics and practitioners to present their different perspectives addressed theoretically as well as in practice concerning the challenges and opportunities of future cities. This includes contributions from decision-makers, architects, urban planners, urban designers, entrepreneurs, and educators to stimulate discussion covering the latest on the challenges and opportunities for better future cities in the different domains of architecture, building science and technology, environmental design, mobility & infrastructure, urban design & landscape, housing & real estate developments, urban planning, governance, socio-cultural & economic development, community engagement, tourism and heritage revitalization.
Cities’ Vocabularies and the Sustainable Development of the Silkroads (Advances in Science, Technology & Innovation)
by Kheir Al-Kodmany Stella Kostopoulou Jacob Wood Gricelda Herrera-FrancoThis book discusses how cities’ identities are formed and developed over time and portrays architecture and the arts as the embodiment of the historical, cultural, and economic characteristics of cities. Furthermore, it explores strategies and solutions to preserve the cultural heritage along the Silk Road, representing a compilation of research addressing the economic and social opportunities and challenges related to the development of a more sustainable and responsible approach to tourism development and the preservation of heritage. As such, it covers a wide range of audiences including economists, architects, planners, tourism experts, and decision-makers interested in making use of cities' available resources and features, offering strategies to explore development opportunities through sustainable and responsible tourism along the Silk Road. This book is a culmination of selected research papers from the first version of the International Conference on "Silk Road Sustainable Tourism Development and Cultural Heritage (SRSTDCH)" which was held in 2021 in collaboration with Aristotle University of Thessaloniki, the European Interdisciplinary Silk Road Tourism Centre, Greece and the 5th Edition of the International Conference on “Cities’ Identity Through Architecture and Arts (CITAA)” which was held in 2021 in collaboration with University of Pisa, Italy.
Citizen Canine: Our Evolving Relationship with Cats and Dogs
by David GrimmDogs are getting lawyers. Cats are getting kidney transplants. Could they one day be fellow citizens?Cats and dogs were once wild animals. Today, they are family members and surrogate children. A little over a century ago, pets didn't warrant the meager legal status of property. Now, they have more rights and protections than any other animal in the country. Some say they're even on the verge of becoming legal persons.How did we get here-and what happens next?In this fascinating exploration of the changing status of dogs and cats in society, pet lover and award-winning journalist David Grimm explores the rich and surprising history of our favorite companion animals. He treks the long and often torturous path from their wild origins to their dark days in the middle ages to their current standing as the most valued animals on Earth. As he travels across the country-riding along with Los Angeles detectives as they investigate animal cruelty cases, touring the devastation of New Orleans in search of the orphaned pets of Hurricane Katrina, and coming face-to-face with wolves and feral cats-Grimm reveals the changing social attitudes that have turned pets into family members, and the remarkable laws and court cases that have elevated them to quasi citizens.The journey to citizenship isn't a smooth one, however. As Grimm finds, there's plenty of opposition to the rising status of cats and dogs. From scientists and farmers worried that our affection for pets could spill over to livestock and lab rats to philosophers who say the only way to save society is to wipe cats and dogs from the face of the earth, the battle lines are being drawn. We are entering a new age of pets-one that is fundamentally transforming our relationship with these animals and reshaping the very fabric of society.For pet lovers or anyone interested in how we decide who gets to be a "person" in today's world, Citizen Canine is a must read. It is a pet book like no other.
Citizen Science: How Ordinary People are Changing the Face of Discovery
by Caren CooperThe engaging history of the people whose contributions to scientific pursuits make us rethink the meaning of the word "scientist." Think you need a degree in science to contribute to important scientific discoveries? Think again. All around the world, in fields ranging from astronomy to zoology, millions of everyday people are choosing to participate in the scientific process. Working in cooperation with scientists in pursuit of information, innovation, and discovery, these volunteers are following protocols, collecting and reviewing data, and sharing their observations. They are our neighbors, our in-laws, and people in the office down the hall. Their story, along with the story of the social good that can result from citizen science, has largely been untold, until now. Citizen scientists are challenging old notions about who can conduct research, where knowledge can be acquired, and even how solutions to some of our biggest societal problems might emerge. In telling their story, Cooper will inspire readers to rethink their own assumptions about the role that individuals can play in gaining scientific understanding and putting that understanding to use as stewards of our world. Citizen Science will be a rallying call-to-arms, and will also function as an authoritative resource for those inspired by the featured stories and message.
Citizen Science: Public Participation in Environmental Research
by Richard Louv John W. Fitzpatrick Janis L. Dickinson Rick BonneyCitizen science enlists members of the public to make and record useful observations, such as counting birds in their backyards, watching for the first budding leaf in spring, or measuring local snowfall. The large numbers of volunteers who participate in projects such as Project FeederWatch or Project BudBurst collect valuable research data, which, when pooled together, create an enormous body of scientific data on a vast geographic scale. In return, such projects aim to increase participants' connections to science, place, and nature, while supporting science literacy and environmental stewardship. In Citizen Science, experts from a variety of disciplines-including scientists and education specialists working at the Cornell Lab of Ornithology, where many large citizen science programs use birds as proxies for biodiversity-share their experiences of creating and implementing successful citizen science projects, primarily those that use massive data sets gathered by citizen scientists to better understand the impact of environmental change.This first and foundational book for this developing field of inquiry addresses basic aspects of how to conduct citizen science projects, including goal-setting, program design, and evaluation, as well as the nuances of creating a robust digital infrastructure and recruiting a large participant base through communications and marketing. An overview of the types of research approaches and techniques demonstrates how to make use of large data sets arising from citizen science projects. A final section focuses on citizen science's impacts and its broad connections to understanding the human dimensions and educational aspects of participation. Citizen Science teaches teams of program developers and researchers how to cross the bridge from success at public engagement to using citizen science data to understand patterns and trends or to test hypotheses about how ecological processes respond to change at large geographic scales. Intended as a resource for a broad audience of experts and practitioners in natural sciences, information science, and social sciences, this book can be used to better understand how to improve existing programs, develop new ones, and make better use of the data resources that have accumulated from citizen science efforts. Its focus on harnessing the impact of "crowdsourcing" for scientific and educational endeavors is applicable to a wide range of fields, especially those that touch on the importance of massive collaboration aimed at understanding and conserving what we can of the natural world.
Citizen Scientist: Searching for Heroes and Hope in an Age of Extinction
by Mary Ellen HannibalA San Francisco Chronicle Best Book of the Year: “Intelligent and impassioned, Citizen Scientist is essential reading for anyone interested in the natural world.”A Nautilus Award Winner in Ecology and EnvironmentAward-winning writer Mary Ellen Hannibal has long reported on scientists’ efforts to protect vanishing species. But it was only through citizen science that she found she could take action herself. As she wades into tide pools, spots hawks, and scours mountains, she discovers the power of the heroic volunteers who are helping scientists measure—and even slow—today’s unprecedented mass extinction. Citizen science may be the future of large-scale field research—and “might be our last, best hope for solving myriad environmental predicaments” (Library Journal).our planet’s last, best hope.“Inspired by the likes of marine biologist Ed Ricketts, [Hannibal] records starfish die-offs, meets the geeks who track deforestation, and plans a web-based supercommunity of citizen scientists to counter what many are calling the sixth great extinction. A cogent call to action.” —Nature“Hannibal’s use of details verges on the sublime.” —East Hampton Star“[A] celebration of nonexperts’ contributions to science.” —Scientific American
Citizens of Worlds: Open-Air Toolkits for Environmental Struggle
by Jennifer GabrysAn unparalleled how-to guide to citizen-sensing practices that monitor air pollution Modern environments are awash with pollutants churning through the air, from toxic gases and intensifying carbon to carcinogenic particles and novel viruses. The effects on our bodies and our planet are perilous. Citizens of Worlds is the first thorough study of the increasingly widespread use of digital technologies to monitor and respond to air pollution. It presents practice-based research on working with communities and making sensor toolkits to detect pollution while examining the political subjects, relations, and worlds these technologies generate. Drawing on data from the Citizen Sense research group, which worked with communities in the United States and the United Kingdom to develop digital-sensor toolkits, Jennifer Gabrys argues that citizen-oriented technologies promise positive change but then collide with entrenched and inequitable power structures. She asks: Who or what constitutes a &“citizen&” in citizen sensing? How do digital sensing technologies enable or constrain environmental citizenship? Spanning three project areas, this study describes collaborations to monitor air pollution from fracking infrastructure, to document emissions in urban environments, and to create air-quality gardens. As these projects show, how people respond to, care for, and struggle to transform environmental conditions informs the political subjects and collectives they become as they strive for more breathable worlds.
Citizenship, Culture and Coexistence: Trends and Dynamics
by Alexander Cotte Poveda Clara Ines Pardo MartinezThis book seeks to contribute to the most recent discussions on Citizenship, Culture and Coexistence in different context considering the importance of these elements for society and urban environments. The book offers different perspectives on citizenship culture and analysis that can be inputs for policy and decision makers to design the policies, strategies and programs that strengthen urban process from culture, art, and education to improve citizen coexistence, respect for differences and better societies in a dynamic world with permanent challenges.
Citric Acid Biotechnology
by Bjørn Kristiansen Michael Mattey Joan LindenThis work covers citric acid fermentation methods including recent advances and approaches. The book looks at all aspects of the fermentation process and should be of interest to those working in biotechnology, microbiology and biochemistry.
Citrus (Crop Production Science In Horticulture Ser.)
by L. Gene Albrigo Dr Lukasz L. Stelinski Lavern TimmerCitrus fruit, originating in Southeast Asia, have been cultivated and enjoyed for over 4000 years. Moreover, they are grown in nearly every country within 40°north-south latitude, the major producers being China, Brazil, the USA, and countries bordering the Mediterranean. This new edition continues to adopt an international perspective on citrus, covering its biology and cultivation as well as considering issues in the citrus industry and providing examples from around the world. The authors include discussion on important topics such as biotechnical advances in citrus genetics, current techniques in breeding, the role of climatic factors in worldwide production, the importance of rootstocks, plant husbandry, pests and diseases, and postharvest technology. They emphasize current theories and technological advances in citriculture, citing specific examples of how they are used and in which regions. Citrus 2nd edition describes the scientific basis of production practices and is aimed at professionals in the industry as well as advanced students of horticulture and allied disciplines within plant science and food science.
Citrus Genetics, Breeding and Biotechnology
by Iqrar Ahmad KhanThis book provides a comprehensive review of citrus breeding, including relevant genetics, molecular biology and biotechnology.