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Crossroads: Environmental Priorities For The Future

by James Gustave Speth Barry Commoner Robert Boyle Cynthia Wilson Richard S. Booth Amos Eno

The environmental movement today is at a critical crossroads. Crossroads: Environmental Priorities for the Future is an in-depth assessment of the movement's successes and failures, and also offers prescriptions for the future. It includes contributions from some of the country's top environmental leaders and activists, including Barry Commoner, Stewart Udall, William K. Reilly, Gus Speth, Jay Hair, Lois Gibbs, Michael Frome, Chuck Little, and William Futrell.

Crossroads between Innate and Adaptive Immunity II (Advances in Experimental Medicine and Biology #633)

by Bali Pulendran Peter D. Katsikis Stephen P. Schoenberger

Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. This volume will include mini-reviews derived from work to be presented at the Aegean Conference: Second Crossroads between Innate and Adaptive Immunity, in Crete, Greece, June 17-22, 2007. This meeting is designed to serve as a forum to discuss the most recent progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of development in complement basic research and the advent and application of new experimental approaches in this field have now allowed us to take an integrated view of the in vivo biology of the complement system. The availability of new reagents (e.g. synthetic and recombinant inhibitors) and animal models (e.g. transgenic and knockout mice) has enabled us to address, in an in vivo setting, its involvement in various pathophysiological conditions. Such studies are shedding new light on the pathogenetic mechanism of complement-related diseases such as autoimmune diseases and inflammatory tissue damage as well as defining new areas of high interest such as the developmental biology of complement. They also provide the basis for developing new therapeutic strategies for these diseases through manipulation of in vivo complement activity. This volume will serve as a resource where the latest development in these specific areas will be discussed in a more focused and detailed manner.

Crossroads between Innate and Adaptive Immunity III (Advances in Experimental Medicine and Biology #780)

by Bali Pulendran Peter D. Katsikis Stephen P. Schoenberger

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “3rd Crossroads between innate and adaptive immunity” which occurred during September 27 - October 2, 2009 at the Minoa Palace Conference Center in Chania, Crete, Greece. This meeting was the third in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The various facets of the innate response, including dendritic cells, T cells, B cells, NK cells, NK-T cells and the complement cascade during the host response to pathogens and tumors is only now starting to be elucidated. The respective fields that focus on these immune cells and molecules have tended to be relatively compartmentalized, and yet emerging evidence points to the interconnectedness of these facets in coordinating the innate response, and its subsequent impact on the adaptive response. The goal of this conference was to initiate cross-talk between these diverse immunological fields, and promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response and ultimately facilitate collaboration between these areas of study. Following on the footsteps of the outstanding success of its precursors, the “3rd Crossroads between Innate and Adaptive Immunity” Aegean Conference was highly successful in bringing together and connecting scientists and experts from around the world to address critical areas of Innate and Adaptive immunity. This volume will include mini-reviews derived from work to be presented at the Aegean Conference: Second Crossroads between Innate and Adaptive Immunity, in Crete, Greece, June 17-22, 2007. This meeting is designed to serve as a forum to discuss the most recent progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of development in complement basic research and the advent and application of new experimental approaches in this field have now allowed us to take an integrated view of the in vivo biology of the complement system. The availability of new reagents (e.g. synthetic and recombinant inhibitors) and animal models (e.g. transgenic and knockout mice) has enabled us to address, in an in vivo setting, its involvement in various pathophysiological conditions. Such studies are shedding new light on the pathogenetic mechanism of complement-related diseases such as autoimmune diseases and inflammatory tissue damage as well as defining new areas of high interest such as the developmental biology of complement. They also provide the basis for developing new therapeutic strategies for these diseases through manipulation of in vivo complement activity. This volume will serve as a resource where the latest development in these specific areas will be discussed in a more focused and detailed manner.

Crossroads Between Innate and Adaptive Immunity IV (Advances in Experimental Medicine and Biology #785)

by Bali Pulendran Peter D. Katsikis Stephen P. Schoenberger

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions. ​

Crossroads Between Innate and Adaptive Immunity V (Advances in Experimental Medicine and Biology #850)

by Bali Pulendran Peter D. Katsikis Stephen P. Schoenberger

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “5th Crossroads Between Innate and Adaptive Immunity”. This meeting was the fifth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive Immunity, a necessary step in the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive Immunity, and maximized scientific interchange through lecture presentations, poster sessions and informal discussions. This volume will include mini-reviews derived from work to be presented at the Aegean Conference: Second Crossroads between Innate and Adaptive Immunity, in Crete, Greece, June 17-22, 2007. This meeting is designed to serve as a forum to discuss the most recent progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of development in complement basic research and the advent and application of new experimental approaches in this field have now allowed us to take an integrated view of the in vivo biology of the complement system. The availability of new reagents (e.g. synthetic and recombinant inhibitors) and animal models (e.g. transgenic and knockout mice) has enabled us to address, in an in vivo setting, its involvement in various pathophysiological conditions. Such studies are shedding new light on the pathogenetic mechanism of complement-related diseases such as autoimmune diseases and inflammatory tissue damage as well as defining new areas of high interest such as the developmental biology of complement. They also provide the basis for developing new therapeutic strategies for these diseases through manipulation of in vivo complement activity. This volume will serve as a resource where the latest development in these specific areas will be discussed in a more focused and detailed manner.

The Crossroads of Science and Faith: Astronomy Through a Christian Worldview

by Susan Benecchi Paula Gossard Gladys Kober

This textbook is designed to be a resource for the Christian community (for both the home school environment and Christian schools) to teach Astronomy and introduce students to the science & faith dialog. The materials in this textbook will strengthen students' faith and prepare them to face a secular university or world environment with confidence. It is designed to equip them to defend their faith with good reasoning and to make them ready to engage unbelievers in respectful discussions. The textbook also encourages the search for truth in every area and promotes dialogue and integration between science and faith while also offering a Christian worldview, where God is the Author, Creator, and Designer of this mind-boggling and awesome universe. The textbook includes many interviews with professional Christian astronomers that we hope will inspire and encourage students and parents alike.

Crow Flight

by Susan Cunningham

The curious flight patterns of crows lead a teen computer programmer down a path of mystery and romance.Gin trusts logic a little too much. She even designs programs to decide what to eat and how to spend her time. All that changes when she's paired with a new transfer student, Felix, on a computer modeling assignment to explain certain anomalies in the behavior of crows.Speaking of anomalies, why is Gin so disappointed that Felix isn't a match for her in the dating app she's designing with local gamers?As she enters Felix's world and digs further into the data behind crow behavior, Gin uncovers a terrible secret. And the wrong decision could equal disaster squared...

Crow Smarts: Inside the Brain of the World's Brightest Bird (Scientists in the Field Series)

by Pamela S. Turner Andy Comins

<P>One of the biggest differences between humans and animals is the ability to understand the idea of "If I do X, Y might happen." New Caledonian crows seem to possess the intelligence to understand this "causal" concept. Why do crows have this ability? <P>What does the crow know and what does it tell us about brain size, the evolution of intelligence, and just who is the smartest creature on the planet? <P>In the latest addition to the Scientists in the Field series, the creators of The Frog Scientist take us to a beautiful Pacific island, where a lively cast of both crows and scientists is waiting to amuse and enlighten us. <P><B>Winner of the 2018 Riverby Award</b>

Crowd Dynamics, Volume 1: Theory, Models, and Safety Problems (Modeling and Simulation in Science, Engineering and Technology)

by Livio Gibelli Nicola Bellomo

This volume explores the complex problems that arise in the modeling and simulation of crowd dynamics in order to present the state-of-the-art of this emerging field and contribute to future research activities. Experts in various areas apply their unique perspectives to specific aspects of crowd dynamics, covering the topic from multiple angles. These include a demonstration of how virtual reality may solve dilemmas in collecting empirical data; a detailed study on pedestrian movement in smoke-filled environments; a presentation of one-dimensional conservation laws with point constraints on the flux; a collection of new ideas on the modeling of crowd dynamics at the microscopic scale; and others. Applied mathematicians interested in crowd dynamics, pedestrian movement, traffic flow modeling, urban planning, and other topics will find this volume a valuable resource. Additionally, researchers in social psychology, architecture, and engineering may find this information relevant to their work.

Crowd Dynamics, Volume 3: Modeling and Social Applications in the Time of COVID-19 (Modeling and Simulation in Science, Engineering and Technology)

by Nicola Bellomo Livio Gibelli

This contributed volume explores innovative research in the modeling, simulation, and control of crowd dynamics. Chapter authors approach the topic from the perspectives of mathematics, physics, engineering, and psychology, providing a comprehensive overview of the work carried out in this challenging interdisciplinary research field. In light of the recent COVID-19 pandemic, special consideration is given to applications of crowd dynamics to the prevention of the spreading of contagious diseases. Some of the specific topics covered in this volume include: - Impact of physical distancing on the evacuation of crowds- Generalized solutions of opinion dynamics models- Crowd dynamics coupled with models for infectious disease spreading- Optimized strategies for leaders in controlling the dynamics of a crowdCrowd Dynamics, Volume 3 is ideal for mathematicians, engineers, physicists, and other researchers working in the rapidly growing field of modeling and simulation of human crowds.

Crowd Dynamics, Volume 4: Analytics and Human Factors in Crowd Modeling (Modeling and Simulation in Science, Engineering and Technology)

by Nicola Bellomo Livio Gibelli

This contributed volume explores innovative research in the modeling, simulation, and control of crowd dynamics. Chapter authors approach the topic from the perspectives of mathematics, physics, engineering, and psychology, providing a comprehensive overview of the work carried out in this challenging interdisciplinary research field. The volume begins with an overview of analytical problems related to crowd modeling. Attention is then given to the importance of considering the social and psychological factors that influence crowd behavior – such as emotions, communication, and decision-making processes – in order to create reliable models. Finally, specific features of crowd behavior are explored, including single-file traffic, passenger movement, modeling multiple groups in crowds, and the interplay between crowd dynamics and the spread of disease.Crowd Dynamics, Volume 4 is ideal for mathematicians, engineers, physicists, and other researchers working in the rapidly growing field of modeling and simulation of human crowds.

The Crowded Greenhouse: Population, Climate Change, and Creating a Sustainable World

by John Firor Judith Jacobsen

What is the best way to move our planet to a safe and sustainable future? This book focuses on two global issues - rapid population growth and a human-induced climate change caused by emissions - that lie at the heart of this problem. John Firor and Judith Jacobsen summarize the current status of these two issues, show how they are related to one another, and prescribe steps that governments, economies, societies, and individuals can adopt to ensure their stability." --BOOK JACKET. Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Crowded Orbits: Conflict and Cooperation in Space

by James Clay Moltz

Space has become increasingly crowded since the end of the Cold War, with new countries, companies, and even private citizens operating satellites and becoming spacefarers. This book offers general readers a valuable primer on space policy from an international perspective. It examines the competing themes of space competition and cooperation while providing readers with an understanding of the basics of space technology, diplomacy, commerce, science, and military applications. The recent expansion of human space activity poses new challenges to existing treaties and other governance tools for space, increasing the likelihood of conflict over a diminishing pool of beneficial locations and resources close to Earth. Drawing on more than twenty years of experience in international space policy debates, James Clay Moltz examines possible avenues for cooperation among the growing pool of space actors, considering their shared interests in space traffic management, orbital debris control, division of the radio frequency spectrum, and the prevention of military conflict. Moltz concludes with policy recommendations for enhanced international collaboration in space situational awareness, scientific exploration, and restraining harmful military activities.

The Crowded Universe: The Search for Living Planets

by Alan Boss

We are nearing a turning point in our quest for life in the universe-we now have the capacity to detect Earth-like planets around other stars. But will we find any? In The Crowded Universe, renowned astronomer Alan Boss argues that based on what we already know about planetary systems, in the coming years we will find abundant Earths, including many that are indisputably alive. Life is not only possible elsewhere in the universe, Boss argues-it is common. Boss describes how our ideas about planetary formation have changed radically in the past decade and brings readers up to date on discoveries of bizarre inhabitants of various solar systems, including our own. America must stay in this new space race, Boss contends, or risk being left out of one of the most profoundly important discoveries of all time: the first confirmed finding of extraterrestrial life.

Crows: Explore the World Life Science

by Michèle Dufresne

This book is about big black birds called crows which can be found in many places.

Crows!: Strange and Wonderful (Strange and Wonderful)

by Laurence Pringle

You see them feeding along the sides of roads or flying to the tops of trees. They are known as common crows, but there is nothing common about them. The familiar sound of "caw, caw, caw" is just one of at least twenty-five distinct sounds crows make in order to communicate with one another. Laurence Pringle examines these remarkable creatures in a fact-filled text that explores how crows talk, behave, and survive. With beautifully detailed illustration by Bob Marstall, young readers get a fascinating look into the world of one of the smartest birds on earth in this winner of the John Burroughs Nature Books for Young Readers Award.

Crucial Event Rehabilitation Therapy: Multifractal Medicine (SpringerBriefs in Bioengineering)

by Bruce West Paolo Grigolini Mauro Bologna

This book describes a new strategy for rehabilitation from injury and/or disease using Crucial Event Therapy. Recent studies have shown that individuals can recuperate more rapidly from surgery and other invasive procedures intended to correct the negative effects of disease or injury through the use of life support systems that operate at the body's natural biofrequencies. The same observation has been clinically shown to reverse the degenerative effects of neurodegenerative diseases such as Parkinson’s and Alzheimer's Disease. Crucial Event Therapy describes medicine as the operational control of the functions of the human body treated as a network-of-networks, with 1/f-variable crucial events coding the dynamic states of health and disease through information flow within a network and information exchange between biomedical networks. A new way of thinking based on the statistics of Cortical Events is presented and the relevant literature is suitably referenced. This is an ideal book for biophysicists and data scientists seeking to understand the connection of complexity measures for the study of consciousness with the clinical aspects of designing a rehabilitation strategy.

Crucibles: The Story of Chemistry from Ancient Alchemy to Nuclear Fission

by Bernard Jaffe

This book is a classic in the field of popular science. Standard reading since the 1930s, it is one of the few historeis of chemistry to concentrate on the lives of the great chemists. Through these dramatic and human stories, it gives an authoritative and entertaining account of the great discoveries and advances in this scientific field. After many printings in three previous editions, this book has been newly revised by the author for this fourth edition. Beginning with Trevisan and his lifelong search for the "philosopher's stone," the author narrates the lives and discoveries of such towering figures as Paracelsus and his chemical treatment of disease; Priestley looking for phlogiston and finding oxygen and carbon dioxide, Lavoisier creating a new language of chemistry; Dalton and his Atomic Theory; Avogadro and the idea of molecules, Mendeleeff arranging the table of elements under his Periodic Law; the Curies isolating radium; Thomson discovering the electron; Moseley and his Law of Atomic Numbers; Lawrence and the construction of the cyclotron; and more. Probably the most dramatic chapter in the book, the account of the development of nuclear fission, ends the story of chemistry at its most monumental achievement. A final chapter discusses some of the consequences of nuclear fission, the discovery of nuclear fusion, and the recent work with subatomic particles. Bernard Jaffe is the author of many other science books and several science textbooks. Upon the original publication of this book, Mr. Jaffe received the Francis Bacon Award for the Humanizing of Knowledge. The American Chemical Society's History of Chemistry Division honored him in 1973 with its Dexter Award for "distinguished achievement in the history of chemistry."

A Crude Look at the Whole: The Science of Complex Systems in Business, Life, and Society

by John H. Miller

Imagine trying to understand a stained glass window by breaking it into pieces and examining it one shard at a time. While you could probably learn a lot about each piece, you would have no idea about what the entire picture looks like. This is reductionism--the idea that to understand the world we only need to study its pieces--and it is how most social scientists approach their work. In A Crude Look at the Whole, social scientist and economist John H. Miller shows why we need to start looking at whole pictures. For one thing, whether we are talking about stock markets, computer networks, or biological organisms, individual parts only make sense when we remember that they are part of larger wholes. And perhaps more importantly, those wholes can take on behaviors that are strikingly different from that of their pieces. Miller, a leading expert in the computational study of complex adaptive systems, reveals astounding global patterns linking the organization of otherwise radically different structures: It might seem crude, but a beehive’s temperature control system can help predict market fluctuations and a mammal’s heartbeat can help us understand the "heartbeat” of a city and adapt urban planning accordingly. From enduring racial segregation to sudden stock market disasters, once we start drawing links between complex systems, we can start solving what otherwise might be totally intractable problems. Thanks to this revolutionary perspective, we can finally transcend the limits of reductionism and discover crucial new ideas. Scientifically founded and beautifully written, A Crude Look at the Whole is a powerful exploration of the challenges that we face as a society. As it reveals, taking the crude look might be the only way to truly see.

Crude Oil Chemistry

by Vasily Simanzhenkov Raphael Idem

Crude Oil Chemistry is foremost a scientifically exact guide to the full family of classical and modern analytical and process technologies in petroleum refining. In widening its vision also to incorporate a geological history of petroleum formation, present-day geopolitical and economic issues, and approaches to redress and improve the delicate ties between the petroleum industry and the environment, this reference succeeds as a total representation of the factors going into the chemistry of crude oil and their outward bound ramifications. The book thoroughly evaluates the chemistry and processing of low API gravity high-sulfur heavy crude oil increasingly relied on in the industry.

Crude Oil Refining: A Simplified Approach

by Marcio Wagner da Silva

This book provides an overview of crude oil refining processes and presents a deep analysis of the current context and challenges imposed on players in the downstream industry. Crude Oil Refining: A Simplified Approach covers traditional processes of the refining industry, the impact of current trends, and technological routes available to help these players survive in a highly competitive environment. FEATURES Offers a simplified approach to crude oil refining processes Discusses economic information related to the downstream business, including refining margins and profitability Introduces newer trends in the industry, such as petrochemical integration, crude-to-chemicals refineries, and renewables coprocessing in crude oil refineries Presents the challenges related to these new trends and offers technological solutions to overcome them for profitable and sustainable operations Describes how the use of biofuels can minimize the environmental impact of transportation fuel in nations of high demand like Brazil Offering a contemporary view of current challenges and opportunities in the downstream oil and gas business, this practical book is aimed at readers working in the fields of petroleum and chemical engineering.

The Cruelest Miles: The Heroic Story of Dogs and Men in a Race Against an Epidemic

by Gay Salisbury Laney Salisbury

"A stirring tale of survival, thanks to man's best friend . . . reflects a transcendent understanding and impeccable research."--Seattle Times When a deadly diphtheria epidemic swept through Nome, Alaska, in 1925, the local doctor knew that without a fresh batch of antitoxin, his patients would die. The lifesaving serum was a thousand miles away, the port was icebound, and planes couldn't fly in blizzard conditions--only the dogs could make it. The heroic dash of dog teams across the Alaskan wilderness to Nome inspired the annual Iditarod Trail Sled Dog Race and immortalized Balto, the lead dog of the last team whose bronze statue still stands in New York City's Central Park. This is the greatest dog story, never fully told until now.

Cruise Ship Astronomy and Astrophotography (The\patrick Moore Practical Astronomy Ser.)

by Gregory I. Redfern

Enrich your next sea vacation with this fun how-to guide to observing and doing astrophotography on water. Collecting together the author’s five decades of astrophotography and teaching experience, this book shares all the practical information you will need to start on your own astronomy adventure.Part I is full of practical advice on what to pack, the best ways to enjoy the night sky from your cruise ship observatory, specific astronomical objects and events to look out for, and myriad other useful tips. Part II gives you a crash course on astrophotography at sea, teaching you the nitty-gritty details of taking pictures of the night sky. Proof that it can be done is provided by the many amazing color astrophotographs taken by the author while following the steps laid out in this book.

Cruise Tourism and Society: A Socio-economic Perspective

by Tihomir Lukovic Michael Vogel Alexis Papathanassis

The growth and increased popularity of cruises is accompanied by a number of sustainability issues concerning the environment, the port economies and societies; on board and at shore. The sustainability imperative ultimately leads to operational, economical as well as image-related challenges for the sector's decision-makers and stakeholders. This collection of peer-reviewed papers, presented during the 3rd International Cruise Conference (Dubrovnik, Croatia), seeks to address those issues and contribute to their management in the mid-term.

Crumbling Genome: The Impact of Deleterious Mutations on Humans

by Alexey S. Kondrashov

A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre?]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

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