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Computational Electrophysiology: Dynamical Systems And Bifurcations (A First Course in “In Silico Medicine” #2)
by Masao Tanaka Zhenxing Pan Junko Inoue Shinji Doi Kunichika TsumotoBiological systems inherently possess much ambiguity or uncertainty. Computational electrophysiology is the one area, from among the vast and rapidly growing discipline of computational and systems biology, in which computational or mathematical models have succeeded. This textbook provides a practical and quick guide to both computational electrophysiology and numerical bifurcation analysis. Bifurcation analysis is a very powerful tool for the analysis of such highly nonlinear biological systems. Bifurcation theory provides a way to analyze the effect of a parameter change on a system and to detect a critical parameter value when the qualitative nature of the system changes. Included in this work are many examples of numerical computations of bifurcation analysis of various models as well as mathematical models with different abstraction levels from neuroscience and electrophysiology. This volume will benefit graduate and undergraduate students as well as researchers in diverse fields of science.
Computational Electrostatics for Biological Applications: Geometric and Numerical Approaches to the Description of Electrostatic Interaction Between Macromolecules
by Walter Rocchia Michela SpagnuoloThis book presents established and new approaches to perform calculations of electrostatic interactions at the nanoscale, with particular focus on molecular biology applications. It is based on the proceedings of the Computational Electrostatics for Biological Applications international meeting, which brought together researchers in computational disciplines to discuss and explore diverse methods to improve electrostatic calculations. Fostering an interdisciplinary approach to the description of complex physical and biological problems, this book encompasses contributions originating in the fields of geometry processing, shape modeling, applied mathematics, and computational biology and chemistry. The main topics covered are theoretical and numerical aspects of the solution of the Poisson-Boltzmann equation, surveys and comparison among geometric approaches to the modelling of molecular surfaces and related discretization and computational issues. It also includes a number of contributions addressing applications in biology, biophysics and nanotechnology. The book is primarily intended as a reference for researchers in the computational molecular biology and chemistry fields. As such, it also aims at becoming a key source of information for a wide range of scientists who need to know how modeling and computing at the molecular level may influence the design and interpretation of their experiments.
Computational Engineering - Introduction to Numerical Methods
by Michael SchäferNumerical simulation methods in all engineering disciplines gains more and more importance.The successful and efficient application of such tools requires certain basic knowledge about the underlying numerical techniques.The text gives a practice-oriented introduction in modern numerical methods as they typically are applied in mechanical, chemical, or civil engineering. Problems from heat transfer, structural mechanics, and fluid mechanics constitute a thematical focus of the text.For the basic understanding of the topic aspects of numerical mathematics, natural sciences, computer science, and the corresponding engineering area are simultaneously important. Usually, the necessary information is distributed in different textbooks from the individual disciplines. In the present text the subject matter is presented in a comprehensive multidisciplinary way, where aspects from the different fields are treated insofar as it is necessary for general understanding. Overarching aspects and important questions related to accuracy, efficiency, and cost effectiveness are discussed.The topics are presented in an introductory manner, such that besides basic mathematical standard knowledge in analysis and linear algebra no further prerequisites are necessary. The book is suitable either for self-study or as an accompanying textbook for corresponding lectures. It can be useful for students of engineering disciplines as well as for computational engineers in industrial practice.
Computational Engineering 2: Theorie und Anwendungen im Bereich der Elektrodynamik
by Jürgen GeiserDas Buch zeigt Theorie und praktische Anwendungen im Bereich des Computational Engineering (berechnendes Ingenieurwesen) für elektrodynamische Anwendungen. Es illustriert sowohl die mathematischen Modelle wie auch die zugehörigen Simulationsmethoden für die verschiedenen Ingenieursanwendungen. Außerdem präsentiert es Strategien zur Verbesserung der numerischen Methoden wie z. B. Zeit-Raum-Verfahren, hyperbolische Löser, Multiskalenlöser oder strukturerhaltende Verfahren sowie Kopplungsverfahren für elektrodynamische und hydrodynamische Modelle auf verschiedenen Zeit- und Raumskalen. Dabei werden Ansätze zur Zerlegung in einfachere und effizient lösbare Teilprobleme vorgestellt. Gerade im Bereich der Multikomponenten- und Multiskalenmodelle bei komplizierten Ingenieursproblemen sind solche neuartigen Multiskalenverfahren wichtig. Weiter werden auch stochastische Modelle im Bereich der Partikelmodelle und deren Einbindung in deterministische Modelle besprochen. Diese neueren Problemstellungen brauchen iterative Löser zur Kopplung der verschiedenen Zeit- und Raumskalen. Die umfangreichen Beispiele aus dem Bereich der Elektrodynamik (inkl. elektromagnetische Felder, Antennenmodelle, Teilchenmodelle im Bereich der Plasmasimulation) geben dem Leser einen Überblick zu den aktuellen Themen und deren praktischer Umsetzung in spätere Simulationsprogramme.
Computational Exome and Genome Analysis (Chapman & Hall/CRC Computational Biology Series)
by Peter N. Robinson Rosario Michael Piro Marten JagerExome and genome sequencing are revolutionizing medical research and diagnostics, but the computational analysis of the data has become an extremely heterogeneous and often challenging area of bioinformatics. <P><P> Computational Exome and Genome Analysis provides a practical introduction to all of the major areas in the field, enabling readers to develop a comprehensive understanding of the sequencing process and the entire computational analysis pipeline.
Computational Finite Element Methods in Nanotechnology
by Sarhan M. MusaComputational Finite Element Methods in Nanotechnology demonstrates the capabilities of finite element methods in nanotechnology for a range of fields. Bringing together contributions from researchers around the world, it covers key concepts as well as cutting-edge research and applications to inspire new developments and future interdisciplinary research. In particular, it emphasizes the importance of finite element methods (FEMs) for computational tools in the development of efficient nanoscale systems. The book explores a variety of topics, including: A novel FE-based thermo-electrical-mechanical-coupled model to study mechanical stress, temperature, and electric fields in nano- and microelectronics The integration of distributed element, lumped element, and system-level methods for the design, modeling, and simulation of nano- and micro-electromechanical systems (N/MEMS) Challenges in the simulation of nanorobotic systems and macro-dimensions The simulation of structures and processes such as dislocations, growth of epitaxial films, and precipitation Modeling of self-positioning nanostructures, nanocomposites, and carbon nanotubes and their composites Progress in using FEM to analyze the electric field formed in needleless electrospinning How molecular dynamic (MD) simulations can be integrated into the FEM Applications of finite element analysis in nanomaterials and systems used in medicine, dentistry, biotechnology, and other areas The book includes numerous examples and case studies, as well as recent applications of microscale and nanoscale modeling systems with FEMs using COMSOL Multiphysics® and MATLAB®. A one-stop reference for professionals, researchers, and students, this is also an accessible introduction to computational FEMs in nanotechnology for those new to the field.
Computational Flexible Multibody Dynamics: A Differential-Algebraic Approach (Differential-Algebraic Equations Forum)
by Bernd SimeonThis monograph, written from a numerical analysis perspective, aims to provide a comprehensive treatment of both the mathematical framework and the numerical methods for flexible multibody dynamics. Not only is this field permanently and rapidly growing, with various applications in aerospace engineering, biomechanics, robotics, and vehicle analysis, its foundations can also be built on reasonably established mathematical models. Regarding actual computations, great strides have been made over the last two decades, as sophisticated software packages are now capable of simulating highly complex structures with rigid and deformable components. The approach used in this book should benefit graduate students and scientists working in computational mechanics and related disciplines as well as those interested in time-dependent partial differential equations and heterogeneous problems with multiple time scales. Additionally, a number of open issues at the frontiers of research are addressed by taking a differential-algebraic approach and extending it to the notion of transient saddle point problems.
Computational Fluid Dynamics (Chapman & Hall/CRC Numerical Analysis and Scientific Computing Series)
by Frédéric MagoulèsExploring new variations of classical methods as well as recent approaches appearing in the field, Computational Fluid Dynamics demonstrates the extensive use of numerical techniques and mathematical models in fluid mechanics. It presents various numerical methods, including finite volume, finite difference, finite element, spectral, smoothed parti
Computational Fluid Dynamics 2010: Proceedings of the Sixth International Conference on Computational Fluid Dynamics, ICCFD6, St Petersburg, Russia, on July 12-16, 2010
by Alexander KuzminThe International Conference on Computational Fluid Dynamics is held every two years and brings together physicists, mathematicians and engineers to review and share recent advances in mathematical and computational techniques for modeling fluid flow. The proceedings of the 2010 conference (ICCFD6) held in St Petersburg, Russia, contain a selection of refereed contributions and are meant to serve as a source of reference for all those interested in the state of the art in computational fluid dynamics.
Computational Fluid Dynamics Applications in Bio and Biomedical Processes: Biotechnology Applications
by Satya Eswari Jujjavarapu Tukendra Kumar Sharda GuptaThis book covers emerging areas in novel design and their hydrodynamic properties relevant to bioreactors, environmental system, electrochemical systems, food processing and biomedical engineering. This book uses an interdisciplinary approach to provide a comprehensive prospective simulation modeling and hydrodynamic study in advanced biotechnological process and includes reviews of the most recent state of art in modeling and simulation of flows in biological process, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas.
Computational Fluid Dynamics Applications in Food Processing (SpringerBriefs in Food, Health, and Nutrition)
by C. AnandharamakrishnanComputational Fluid Dynamics (CFD) has been applied extensively to great benefit in the food processing sector. Its numerous applications include: predicting the gas flow pattern and particle histories, such as temperature, velocity, residence time, and impact position during spray drying; modeling of ovens to provide information about temperature and airflow pattern throughout the baking chamber to enhance heat transfer and in turn final product quality; designing hybrid heating ovens, such as microwave-infrared, infrared-electrical or microwave-electrical ovens for rapid baking; model the dynamics of gastrointestinal contents during digestion based on the motor response of the GI tract and the physicochemical properties of luminal contents; retort processing of canned solid and liquid foods for understanding and optimization of the heat transfer processes. This Brief will recapitulate the various applications of CFD modeling, discuss the recent developments in this field, and identify the strengths and weaknesses of CFD when applied in the food industry.
Computational Fluid Dynamics Simulation of Spray Dryers: An Engineer’s Guide (Advances in Drying Science and Technology #Vol. 2)
by Meng Wai WooBridging the gap in understanding between the spray drying industry and the numerical modeler on spray drying, Computational Fluid Dynamics Simulation of Spray Dryers: An Engineer’s Guide shows how to numerically capture important physical phenomena within a spray drying process using the CFD technique. It includes numerical strategies to effectively describe these phenomena, which are collated from research work and CFD industrial consultation, in particular to the dairy industry. Along with showing how to set up models, the book helps readers identify the capabilities and uncertainties of the CFD technique for spray drying. After briefly covering the basics of CFD, the book discusses airflow modeling, atomization and particle tracking, droplet drying, quality modeling, agglomeration and wall deposition modeling, and simulation validation techniques. The book also answers questions related to common challenges in industrial applications.
Computational Fluid Dynamics and Heat Transfer (Series In Computational And Physical Processes In Mechanics And Thermal Sciences Ser.)
by Pradip MajumdarThis book provides a thorough understanding of fluid dynamics and heat and mass transfer. The Second Edition contains new chapters on mesh generation and computational modeling of turbulent flow. Combining theory and practice in classic problems and computer code, the text includes numerous worked-out examples. Students will be able to develop computational analysis models for complex problems more efficiently using commercial codes such as ANSYS, STAR CCM+, and COMSOL. With detailed explanations on how to implement computational methodology into computer code, students will be able to solve complex problems on their own and develop their own customized simulation models, including problems in heat transfer, mass transfer, and fluid flows. These problems are solved and illustrated in step-by-step derivations and figures. FEATURES Provides unified coverage of computational heat transfer and fluid dynamics Covers basic concepts and then applies computational methods for problem analysis and solution Covers most common higher-order time-approximation schemes Covers most common and advanced linear solvers Contains new chapters on mesh generation and computer modeling of turbulent flow Computational Fluid Dynamics and Heat Transfer, Second Edition, is valuable to engineering instructors and students taking courses in computational heat transfer and computational fluid dynamics.
Computational Fluid Dynamics and its Applications in Echinoderm Palaeobiology (Elements of Paleontology)
by Imran A. RahmanComputational fluid dynamics (CFD), which involves using computers to simulate fluid flow, is emerging as a powerful approach for elucidating the palaeobiology of ancient organisms. Here, Imran A. Rahman describes its applications for studying fossil echinoderms. When properly configured, CFD simulations can be used to test functional hypotheses in extinct species, informing on aspects such as feeding and stability. They also show great promise for addressing ecological questions related to the interaction between organisms and their environment. CFD has the potential to become an important tool in echinoderm palaeobiology over the coming years.
Computational Fluid Dynamics and the Theory of Fluidization: Applications of the Kinetic Theory of Granular Flow
by Dimitri Gidaspow Huilin Lu Shuyan WangThis book is for engineers and students to solve issues concerning the fluidized bed systems. It presents an analysis that focuses directly on the problem of predicting the fluid dynamic behavior which empirical data is limited or unavailable. The second objective is to provide a treatment of computational fluidization dynamics that is readily accessible to the non-specialist. The approach adopted in this book, starting with the formulation of predictive expressions for the basic conservation equations for mass and momentum using kinetic theory of granular flow. The analyses presented in this book represent a body of simulations and experiments research that has appeared in numerous publications over the last 20 years. This material helps to form the basis for university course modules in engineering and applied science at undergraduate and graduate level, as well as focused, post-experienced courses for the process, and allied industries.
Computational Fluid Dynamics for Built and Natural Environments
by Zhiqiang (John) ZhaiThis book introduces readers to the fundamentals of simulating and analyzing built and natural environments using the Computational Fluid Dynamics (CFD) method. CFD offers a powerful tool for dealing with various scientific and engineering problems and is widely used in diverse industries. This book focuses on the most important aspects of applying CFD to the study of urban, buildings, and indoor and outdoor environments. Following the logical procedure used to prepare a CFD simulation, the book covers e.g. the governing equations, boundary conditions, numerical methods, modeling of different fluid flows, and various turbulence models. Furthermore, it demonstrates how CFD can be applied to solve a range of engineering problems, providing detailed hands-on exercises on air and water flow, heat transfer, and pollution dispersion problems that typically arise in the study of buildings and environments. The book also includes practical guidance on analyzing and reporting CFD results, as well as writing CFD reports/papers.
Computational Fluid Dynamics for Engineers
by Mikael Mortensen Love Håkansson Ronnie Andersson Bengt Andersson Berend Van Wachem Rahman SudiyoComputational fluid dynamics, CFD, has become an indispensable tool for many engineers. This book gives an introduction to CFD simulations of turbulence, mixing, reaction, combustion and multiphase flows. The emphasis on understanding the physics of these flows helps the engineer to select appropriate models to obtain reliable simulations. Besides presenting the equations involved, the basics and limitations of the models are explained and discussed. The book combined with tutorials, project and power-point lecture notes (all available for download) forms a complete course. The reader is given hands-on experience of drawing, meshing and simulation. The tutorials cover flow and reactions inside a porous catalyst, combustion in turbulent non-premixed flow, and multiphase simulation of evaporation spray respectively. The project deals with design of an industrial-scale selective catalytic reduction process and allows the reader to explore various design improvements and apply best practice guidelines in the CFD simulations.
Computational Fluid Dynamics for Engineers and Scientists
by Sreenivas JayantiThis book offers a practical, application-oriented introduction to computational fluid dynamics (CFD), with a focus on the concepts and principles encountered when using CFD in industry. Presuming no more knowledge than college-level understanding of the core subjects, the book puts together all the necessary topics to give the reader a comprehensive introduction to CFD. It includes discussion of the derivation of equations, grid generation and solution algorithms for compressible, incompressible and hypersonic flows. The final two chapters of the book are intended for the more advanced user. In the penultimate chapter, the special difficulties that arise while solving practical problems are addressed. Distinction is made between complications arising out of geometrical complexity and those arising out of the complexity of the physics (and chemistry) of the problem. The last chapter contains a brief discussion of what can be considered as the Holy Grail of CFD, namely, finding the optimal design of a fluid flow component. A number of problems are given at the end of each chapter to reinforce the concepts and ideas discussed in that chapter. CFD has come of age and is widely used in industry as well as in academia as an analytical tool to investigate a wide range of fluid flow problems. This book is written for two groups: for those students who are encountering CFD for the first time in the form of a taught lecture course, and for those practising engineers and scientists who are already using CFD as an analysis tool in their professions but would like to deepen and broaden their understanding of the subject.
Computational Fluid Dynamics for Mechanical Engineering
by George QinThis textbook presents the basic methods, numerical schemes, and algorithms of computational fluid dynamics (CFD). Readers will learn to compose MATLAB® programs to solve realistic fluid flow problems.Newer research results on the stability and boundedness of various numerical schemes are incorporated. The book emphasizes large eddy simulation (LES) in the chapter on turbulent flow simulation besides the two-equation models. Volume of fraction (VOF) and level-set methods are the focus of the chapter on two-phase flows.The textbook was written for a first course in computational fluid dynamics (CFD) taken by undergraduate students in a Mechanical Engineering major.Access the Support Materials: https://www.routledge.com/9780367687298.
Computational Fluid Dynamics for Wind Engineering
by R. Panneer SelvamCOMPUTATIONAL FLUID DYNAMICS FOR WIND ENGINEERING An intuitive and comprehensive exploration of computational fluid dynamics in the study of wind engineering Computational Fluid Dynamics for Wind Engineering provides readers with a detailed overview of the use of computational fluid dynamics (CFD) in understanding wind loading on structures, a problem becoming more pronounced as urban density increases and buildings become larger. The work emphasizes the application of CFD to practical problems in wind loading and helps readers understand important associated factors such as turbulent flow around buildings and bridges. The author, with extensive research experience in this and related fields, offers relevant and engaging practice material to help readers learn and retain the concepts discussed, and each chapter includes accessible summaries at the end. In addition, the use of the OpenFOAM tool—an open-source wind engineering application—is explored. Computational Fluid Dynamics for Wind Engineering covers topics such as: Fluid mechanics, turbulence in fluid mechanics, turbulence modelling, and mathematical modelling of wind engineering problems The finite difference method for CFD, solutions to the incompressible Navier-Stokes equations, visualization, and animation in CFD, and the application of CFD to building and bridge aerodynamics How to compare CFD analysis with wind tunnel measurements, field measurements, and the ASCE-7 pressure coefficients Wind effects and strain on large structures Providing comprehensive coverage of how CFD can explain wind load on structures along with helpful examples of practical applications, Computational Fluid Dynamics for Wind Engineering serves as an invaluable resource for senior undergraduate students, graduate students, researchers and practitioners of civil and structural engineering.
Computational Fluid Dynamics in Food Processing (Contemporary Food Engineering)
by Da-Wen SunSince many processes in the food industry involve fluid flow and heat and mass transfer, Computational Fluid Dynamics (CFD) provides a powerful early-stage simulation tool for gaining a qualitative and quantitative assessment of the performance of food processing, allowing engineers to test concepts all the way through the development of a process or system. <P><P>Published in 2007, the first edition was the first book to address the use of CFD in food processing applications, and its aims were to present a comprehensive review of CFD applications for the food industry and pinpoint the research and development trends in the development of the technology; to provide the engineer and technologist working in research, development, and operations in the food industry with critical, comprehensive, and readily accessible information on the art and science of CFD; and to serve as an essential reference source to undergraduate and postgraduate students and researchers in universities and research institutions. This will continue to be the purpose of this second edition. <P><P>In the second edition, in order to reflect the most recent research and development trends in the technology, only a few original chapters are updated with the latest developments. Therefore, this new edition mostly contains new chapters covering the analysis and optimization of cold chain facilities, simulation of thermal processing and modeling of heat exchangers, and CFD applications in other food processes.
Computational Fluid Dynamics in Industrial Combustion
by Charles E. Baukal Vladimir Y. Cershtein Xianming LiAlthough many books have been written on computational fluid dynamics (CFD) and many written on combustion, most contain very limited coverage of the combination of CFD and industrial combustion. Furthermore, most of these books are written at an advanced academic level, emphasize theory over practice, and provide little help to engineers who need
Computational Fluid Dynamics: An Introduction for Mechanical Engineering Students (Mathematical Engineering)
by Sergei S. SazhinThis book introduces the basic concepts of the Computational Fluid Dynamics (CFD) of single-phase and multiphase flows. While the opening chapter focuses on the key equations that are solved numerically using classical CFD codes, the intention is not just to show these equations, but also to present key ideas of the calculus on which the formulations of these equations, and the analysis of other parts of the book, are based. Various approaches to the discretisation of conservation equations describing single-phase flows and the methods for solving the algebraic equations are demonstrated, including the details of some derivations usually omitted in classical textbooks. Also, the details of the SIMPLE algorithm is described. In contrast to most classical CFD books, this textbook also develops the basic principles of modelling multiphase flows, including approaches to modelling spray formation and droplet dynamics, analyses of flow instabilities, and droplet heating and evaporation. Completing the coverage, approaches to modelling the processes in multicomponent droplets, including puffing and micro-explosion in composite droplets, are discussed and the modelling of thermal radiation transfer using CFD codes is treated.
Computational Fluid Dynamics: Incompressible Turbulent Flows
by Takeo Kajishima Kunihiko TairaThis textbook presents numerical solution techniques for incompressible turbulent flows that occur in a variety of scientific and engineering settings including aerodynamics of ground-based vehicles and low-speed aircraft, fluid flows in energy systems, atmospheric flows, and biological flows. This book encompasses fluid mechanics, partial differential equations, numerical methods, and turbulence models, and emphasizes the foundation on how the governing partial differential equations for incompressible fluid flow can be solved numerically in an accurate and efficient manner. Extensive discussions on incompressible flow solvers and turbulence modeling are also offered. This text is an ideal instructional resource and reference for students, research scientists, and professional engineers interested in analyzing fluid flows using numerical simulations for fundamental research and industrial applications.
Computational Fluid Dynamics: Methodology and Numerics (Infosys Science Foundation Series)
by Dia Zeidan Lucy T. Zhang Eric Goncalves Da Silva Arturo HidalgoThis book reveals the latest research outputs in computational fluid dynamics. It contains selected chapters on fluid flow problems authored by international researchers. It highlights the current trends in the modelling and simulation aspects of fluid dynamics. Even though modelling and simulations in fluid dynamics are now considered mainstream in analysing fluid flows, heat and mass transfer problems, researchers are still exploring various numerical approaches and recipes to achieve better accuracy and efficiency for challenging applications in biomedical, aerospace, renewable energy and other industrial engineering applications. The book aims to bring many of the diverse modelling and simulation tools in one place and to advance existing progress in the emerging sciences of fluid dynamics. It summarizes current mathematical and physical modelling approaches as well as computational techniques applicable to fluid dynamics. The book would be of special interest to physicists and researchers in several fields related to computational, applied sciences and engineering.