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Connective Tissue: Histophysiology, Biochemistry, Molecular Biology
by Nikolay Petrovich Omelyanenko Leonid Ilyich Slutsky Sergey Pavlovich MironovConnective tissue is a multicomponent, polyfunctional complex of cells and extracellular matrix that serves as a framework for all organs, combining to form a unified organism. It is a structure responsible for numerous vital functions such as tissue-organ integration, morphogenesis, homeostasis maintenance, biomechanical support, and more. The reg
Connectome: How the Brain's Wiring Makes Us Who We Are
by Sebastian Seung&“Accessible, witty . . . an important new researcher, philosopher and popularizer of brain science . . . on par with cosmology&’s Brian Greene and the late Carl Sagan&” (The Plain Dealer). One of the Wall Street Journal&’s 10 Best Nonfiction Books of the Year and a Publishers Weekly &“Top Ten in Science&” Title Every person is unique, but science has struggled to pinpoint where, precisely, that uniqueness resides. Our genome may determine our eye color and even aspects of our character. But our friendships, failures, and passions also shape who we are. The question is: How? Sebastian Seung is at the forefront of a revolution in neuroscience. He believes that our identity lies not in our genes, but in the connections between our brain cells—our particular wiring. Seung and a dedicated group of researchers are leading the effort to map these connections, neuron by neuron, synapse by synapse. It&’s a monumental effort, but if they succeed, they will uncover the basis of personality, identity, intelligence, memory, and perhaps disorders such as autism and schizophrenia. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. &“This is complicated stuff, and it is a testament to Dr. Seung&’s remarkable clarity of exposition that the reader is swept along with his enthusiasm, as he moves from the basics of neuroscience out to the farthest regions of the hypothetical, sketching out a spectacularly illustrated giant map of the universe of man.&” —TheNew York Times &“An elegant primer on what&’s known about how the brain is organized and how it grows, wires its neurons, perceives its environment, modifies or repairs itself, and stores information. Seung is a clear, lively writer who chooses vivid examples.&” —TheWashington Post
Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology
by Ernesto Oviedo-Orta Brenda R. Kwak William Howard EvansPlasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes. This book assembles and synthesizes four decades of the most important research carried out in this field. The chapters focus on the latest progress made on translating the knowledge gained to specific treatment modalities, including approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system and enhancing epithelial tissue repair. The book will inform and update specialists, clinical practitioners and those studying the potential for commercial applications.
Connexin Hemichannels: Methods and Protocols (Methods in Molecular Biology #2801)
by Fabio Mammano Mauricio RetamalThis volume explores the latest developments in the study of connexin hemichannels (HCs). The chapters in this book cover topics such as purification, reconstitution, and functional analysis of connexin HCs; spatial and temporal localization of connexins in cells using confocal microscopy; evaluation of connexin HC activity in vivo; generation of connexin-expressing stable cell pools; and automated assessment of cutaneous pathology in a mouse model of HC dysfunction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Connexin Hemichannels: Methods and Protocols is a valuable resource that discusses the importance of HCs as drug targets, and how studying them is essential to identifying newcompounds capable of modulating HC function selectively and specifically.
Connexin Methods and Protocols (Methods in Molecular Biology #154)
by Christian Giaume Roberto BruzzoneLeading investigators describe in detail their best techniques to study the cellular and molecular biology of connexins, as well as physiological properties. These forefront methods are specifically designed to investigate the life of connexins from biosynthesis to assembly into gap junction channels, and also include powerful assays to perform functional studies on these routes of cell-cell communication. Also discussed are the many specific theoretical aspects of connexin biology and physiology. Cutting-edge and highly practical, Connexin Methods and Protocols offers laboratory researchers a comprehensive collection of proven methods for studying the role of connexins in intercellular communication and human genetic disorders, as well as finding promising new therapeutics for those disorders.
Connexins: A Guide
by Andrew Harris Darren LockeConnexins: A Guide is a practical and valuable reference and text covering a wide scope of information about the connexin family of membrane channel proteins. The editors and contributing authors intend for this cutting-edge work to be informative to scientists wishing to learn about the field, as well as to those who are active researchers in this area. Connexins: A Guide masterfully addresses specific needs of the scientific community; it is a comprehensive and comprehensible narrative of the uncommonly diverse connexin field, making previously hard-to-find information easily accessible, while also presenting intelligible insights into the extensive experimental methods and conceptual frameworks necessary to appreciate and understand the important roles that connexin channel proteins play in health and disease.
Connexins: The Gap Junction Proteins (SpringerBriefs in Biochemistry and Molecular Biology)
by Mahboob Ul HussainGap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins. The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.
Connie Willis’s Science Fiction: Doomsday Every Day (Routledge Studies in Contemporary Literature)
by Carissa Turner SmithIn spite of Connie Willis’s numerous science fiction awards and her groundbreaking history as a woman in the field, there is a surprising dearth of critical publication surrounding her work. Taking Doomsday Book as its cue, this collection argues that Connie Willis’s most famous novel, along with the rest of her oeuvre, performs science fiction’s task of cognitive estrangement by highlighting our human inability to read the times correctly—and yet also affirming the ethical imperative to attempt to truly observe and record our temporal location. Willis’s fiction emphasizes that doomsdays happen every day, and they risk being forgotten by some, even as their trauma repeats for others. However, disasters also have the potential to upend accepted knowledge and transform the social order for the better, and this collection considers the ways that Willis pairs comic and tragic modes to reflect these uncertainties.
Conquering the Physics GRE (Third Edition)
by Yoni Kahn Adam AndersonThe Physics GRE plays a significant role in deciding admissions to nearly all US physics Ph.D. programs, yet few exam-prep books focus on the test's actual content and unique structure. Recognized as one of the best student resources available, this tailored guide has been thoroughly updated for the current Physics GRE. It contains carefully selected review material matched to all of the topics covered, as well as tips and tricks to help solve problems under time pressure. It features three full-length practice exams, revised to accurately reflect the difficulty of the current test, with fully worked solutions so that students can simulate taking the test, review their preparedness, and identify areas in which further study is needed. Written by working physicists who took the Physics GRE for their own graduate admissions to the Massachusetts Institute of Technology, this self-contained reference guide will help students achieve their best score.
Conquest of Body: Biopower with Biotechnology (SpringerBriefs in Philosophy)
by Polona TratnikThis book reflects on the phenomenon of biotechnology and how it affects the body and discusses a number of related issues, including visualization, mediation, and epistemology. The author offers a compelling thesis, arguing that the exploration of the human body has one ultimate aim: to gain knowledge of it and to conquer it. Exploration of body has an intrinsic link to power, since knowledge is constitutive for the power over the body. Ultimately the conquest of body means the power to intervene into life processes. The book breaks new ground with its study of body visualizations, from the Renaissance drawings to the medical imaging. In particular, it investigates their complex mediality. It also considers the extension and the reach of biopower that is now possible thanks to a wide range of engineering applications. The author originally questions the research approach by rethinking the relationship between mental and sensual examination. She takes into consideration the epistemological problem of the two modes of exploration: obtaining knowledge from empirical exploration and projecting that knowledge to the object of exploration.
Conquest of Mind: Phrenology and Victorian Social Thought (Routledge Library Editions: The Victorian World #13)
by David de GiustinoFirst published in 1975. This study examines one of the popular scientific philosophies of the nineteenth-century. The first part deals with the reception and diffusion of phrenology in Britain, its usefulness to various professions, and its challenge to traditional religion. The second part considers the application of phrenology in two separate social movements: prison reform and national education. This title will be of interest to students of history and philosophy.
Conscience: The Origins Of Moral Intuition
by Patricia ChurchlandHow do we determine right from wrong? Conscience illuminates the answer through science and philosophy. In her brilliant work Touching a Nerve, Patricia S. Churchland, the distinguished founder of neurophilosophy, drew from scientific research on the brain to understand its philosophical and ethical implications for identity, consciousness, free will, and memory. In Conscience, she explores how moral systems arise from our physical selves in combination with environmental demands. All social groups have ideals for behavior, even though ethics vary among different cultures and among individuals within each culture. In trying to understand why, Churchland brings together an understanding of the influences of nature and nurture. She looks to evolution to elucidate how, from birth, our brains are configured to form bonds, to cooperate, and to care. She shows how children grow up in society to learn, through repetition and rewards, the norms, values, and behavior that their parents embrace. Conscience delves into scientific studies, particularly the fascinating work on twins, to deepen our understanding of whether people have a predisposition to embrace specific ethical stands. Research on psychopaths illuminates the knowledge about those who abide by no moral system and the explanations science gives for these disturbing individuals. Churchland then turns to philosophy—that of Socrates, Aquinas, and contemporary thinkers like Owen Flanagan—to explore why morality is central to all societies, how it is transmitted through the generations, and why different cultures live by different morals. Her unparalleled ability to join ideas rarely put into dialogue brings light to a subject that speaks to the meaning of being human.
Conscientious Objections: Stirring Up Trouble About Language, Technology and Education
by Neil PostmanIn a series of feisty and ultimately hopeful essays, one of America's sharpest social critics casts a shrewd eye over contemporary culture to reveal the worst -- and the best -- of our habits of discourse, tendencies in education, and obsessions with technological novelty. Readers will find themselves rethinking many of their bedrock assumptions: Should education transmit culture or defend us against it? Is technological innovation progress or a peculiarly American addiction? When everyone watches the same television programs -- and television producers don't discriminate between the audiences for Sesame Street and Dynasty -- is childhood anything more than a sentimental concept? Writing in the traditions of Orwell and H.L. Mencken, Neil Postman sends shock waves of wit and critical intelligence through the cultural wasteland.From the Trade Paperback edition.
Conscious Business in Deutschland: Bewertung des Status quo und Ausblick auf ein neues Paradigma in Wirtschaft und Gesellschaft
by Nicolas Josef Stahlhofer Christian Schmidkonz Patricia KraftDieses Buch stellt Conscious Business im Sinne eines bewussten Wirtschaftens als einen sich ständig erweiternden und kraftvollen Ansatz vor, um Organisationen neu zu erfinden und auf eine menschliche und nutzbringende Weise zu gestalten. Es untersucht insbesondere die Charakteristika, Haupttreiber und Herausforderungen von Conscious Businesses in Deutschland. Das Buch bietet einen strukturierten Überblick über die aktuelle Situation des Konzepts und skizziert wichtige Aspekte, die es zu beachten gilt, um eigenständige Entscheidungen zu treffen. Vier Fallstudien erfolgreicher bewusster Unternehmen - unterschiedlich in Größe, Branche, Rechtsform und internationaler Ausrichtung - zeigen konkrete Best-Practice-Beispiele auf und belegen die Fähigkeit des Ansatzes, zielführende und zugleich profitable Geschäftsmodelle zu entwickeln.
Conscious Business in Germany: Assessing the Current Situation and Creating an Outlook for a New Paradigm (CSR, Sustainability, Ethics & Governance)
by Nicolas Josef Stahlhofer Christian Schmidkonz Patricia KraftThis book presents conscious business as a constantly expanding and powerful approach to reinvent and shape organizations in a human and beneficial manner. In particular it examines the core characteristics, main drivers and challenges of conscious businesses in Germany. The book offers a structured overview of the current situation of the concept and outlines important issues that need to be considered in order to make independent decisions. Four case studies of successful conscious companies - differing in terms of their size, industry, legal form and international orientation - reveal concrete best practices and provide evidence for the approach's ability to deliver business paradigms that are simultaneously purposeful and profitable.
Conscious Experience: A Logical Inquiry
by Anil GuptaHow, theorists ask, can our private experiences guide us to knowledge of a mind-independent reality? Exploring topics in logic, philosophy of mind, and epistemology, Anil Gupta proposes a new answer to this age-old question, explaining how conscious experience contributes to the rationality and content of empirical beliefs.
Conscious Mind in the Physical World
by E.J SquiresWe have seen remarkable progress in our detailed understanding of the physical world, from the smallest constituents of atoms to the remotest distances seen by telescopes. However, we have yet to explore the phenomenon of consciousness. Can physical things be conscious or is consciousness something else, forever outside the range of physics? And ho
Conscious: A Brief Guide to the Fundamental Mystery of the Mind
by Annaka HarrisAs concise and enlightening as Seven Brief Lessons on Physics and Astrophysics for People in a Hurry, this mind-expanding dive into the mystery of consciousness is an illuminating meditation on the self, free will, and felt experience.What is consciousness? How does it arise? And why does it exist? We take our experience of being in the world for granted. But the very existence of consciousness raises profound questions: Why would any collection of matter in the universe be conscious? How are we able to think about this? And why should we?In this wonderfully accessible book, Annaka Harris guides us through the evolving definitions, philosophies, and scientific findings that probe our limited understanding of consciousness. Where does it reside, and what gives rise to it? Could it be an illusion, or a universal property of all matter? As we try to understand consciousness, we must grapple with how to define it and, in the age of artificial intelligence, who or what might possess it. Conscious offers lively and challenging arguments that alter our ideas about consciousness—allowing us to think freely about it for ourselves, if indeed we can.
Consciousness
by Rita CarterA guide to the hardest problem in science: the nature of consciousness.Is consciousness merely an illusion, a by-product of our brain's workings, or is it, as the latest physics may suggest, the basis for all reality? Your perception of the world around you, your consciousness, should be the one thing you could talk about with absolute confidence. But nothing about consciousness is clear-cut and understanding it is perhaps the hardest problem facing modern science. But some extraordinary insights gathered by the latest research suggest that the answers are within our grasp. Building on the success of her bestselling book MAPPING THE MIND, Rita Carter gathers these insights together to throw a new light on consciousness, its nature, its origins and its purpose.
Consciousness Demystified (The\mit Press Ser.)
by Todd E. Feinberg Jon M. MallattDemystifying consciousness: how subjective experience can be explained by natural brain and evolutionary processes.Consciousness is often considered a mystery. How can the seemingly immaterial experience of consciousness be explained by the material neurons of the brain? There seems to be an unbridgeable gap between understanding the brain as an objectively observed biological organ and accounting for the subjective experiences that come from the brain (and life processes). In this book, Todd Feinberg and Jon Mallatt attempt to demystify consciousness—to naturalize it, by explaining that the subjective, experiencing aspects of consciousness are created by natural brain processes that evolved in natural ways. Although subjective experience is unique in nature, they argue, it is not necessarily mysterious. We need not invoke the unknown or unknowable to explain its creation.Feinberg and Mallatt flesh out their theory of neurobiological naturalism (after John Searle's biological naturalism) that recognizes the many features that brains share with other living things, lists the neural features unique to conscious brains, and explains the subjective–objective barrier naturally. They investigate common neural features among the diverse groups of animals that have primary consciousness—the type of consciousness that experiences both sensations received from the world and affects such as emotions. They map the evolutionary development of consciousness and find an uninterrupted progression over time, without inserting any mysterious forces or exotic physics. Finally, bridging the previously unbridgeable, they show how subjective experience, although different from objective observation, can be naturally explained.
Consciousness Explained
by Daniel C. Dennett"Brilliant...as audacious as its title....Mr. Dennett's exposition is nothing short of brilliant." --George Johnson, New York Times Book Review Consciousness Explained is a a full-scale exploration of human consciousness. In this landmark book, Daniel Dennett refutes the traditional, commonsense theory of consciousness and presents a new model, based on a wealth of information from the fields of neuroscience, psychology, and artificial intelligence. Our current theories about conscious life-of people, animal, even robots--are transformed by the new perspectives found in this book.
Consciousness Studies in Sciences and Humanities: Eastern and Western Perspectives (Studies in Neuroscience, Consciousness and Spirituality #8)
by Anand Srivastav Prem Saran Satsangi Anna Margaretha HoratschekThis book presents consciousness models from Eastern and Western perspectives that accommodate current scientific research in the natural sciences and humanities, from neurological experiments through philosophical enquiries to spiritual approaches. It offers up to date research from key disciplines in consciousness studies ranging from neurology, quantum mechanics, algorithmic science, mathematics, and astrophysics to literary studies, philosophy, and (comparative) theology. The volume examines the dichotomy between Western and Eastern perceptions of consciousness – where consciousness is perceived as brain activity by Western scientists, and as a divine presence by various religions, especially in the East. The essays contextualize each other and reciprocally illuminate the potential and limits of the respective approaches. The texts aim at a transdisciplinary and transcultural exchange of ideas in consciousness studies and address a readership from interested lay-readers to experts of the field. The volume is of interest to researchers of consciousness studies.
Consciousness and Mental Life
by Daniel N. RobinsonIn recent decades, issues that reside at the center of philosophical and psychological inquiry have been absorbed into a scientific framework variously identified as "brain science," "cognitive science," and "cognitive neuroscience." Scholars have heralded this development as revolutionary, but a revolution implies an existing method has been overturned in favor of something new. What long-held theories have been abandoned or significantly modified in light of cognitive neuroscience? Consciousness and Mental Life questions our present approach to the study of consciousness and the way modern discoveries either mirror or contradict understandings reached in the centuries leading up to our own. Daniel N. Robinson does not wage an attack on the emerging discipline of cognitive science. Rather, he provides the necessary historical context to properly evaluate the relationship between issues of consciousness and neuroscience and their evolution over time. Robinson begins with Aristotle and the ancient Greeks and continues through to René Descartes, David Hume, William James, Daniel Dennett, John Searle, Richard Rorty, Hilary Putnam, and Derek Parfit. Approaching the issue from both a philosophical and a psychological perspective, Robinson identifies what makes the study of consciousness so problematic and asks whether cognitive neuroscience can truly reveal the origins of mental events, emotions, and preference, or if these occurrences are better understood by studying the whole person, not just the brain. Well-reasoned and thoroughly argued, Consciousness and Mental Life corrects many claims made about the success of brain science and provides a valuable historical context for the study of human consciousness.
Consciousness and Mental Life
by Daniel N. RobinsonIn recent decades, issues that reside at the center of philosophical and psychological inquiry have been absorbed into a scientific framework variously identified as "brain science," "cognitive science," and "cognitive neuroscience." Scholars have heralded this development as revolutionary, but a revolution implies an existing method has been overturned in favor of something new. What long-held theories have been abandoned or significantly modified in light of cognitive neuroscience? Consciousness and Mental Life questions our present approach to the study of consciousness and the way modern discoveries either mirror or contradict understandings reached in the centuries leading up to our own. Daniel N. Robinson does not wage an attack on the emerging discipline of cognitive science. Rather, he provides the necessary historical context to properly evaluate the relationship between issues of consciousness and neuroscience and their evolution over time. Robinson begins with Aristotle and the ancient Greeks and continues through to René Descartes, David Hume, William James, Daniel Dennett, John Searle, Richard Rorty, Hilary Putnam, and Derek Parfit. Approaching the issue from both a philosophical and a psychological perspective, Robinson identifies what makes the study of consciousness so problematic and asks whether cognitive neuroscience can truly reveal the origins of mental events, emotions, and preference, or if these occurrences are better understood by studying the whole person, not just the brain. Well-reasoned and thoroughly argued, Consciousness and Mental Life corrects many claims made about the success of brain science and provides a valuable historical context for the study of human consciousness.
Consciousness and Science Fiction (Science and Fiction)
by Damien BroderickScience fiction explores the wonderful, baffling and wildly entertaining aspects of a universe unimaginably old and vast, and with a future even more immense. It reaches into that endless cosmos with the tools of rational investigation and storytelling. At the core of both science and science fiction is the engaged human mind--a consciousness that sees and feels and thinks and loves. But what is this mind, this aware and self-aware consciousness that seems unlike anything else we experience? What makes consciousness the Hard Problem of philosophy, still unsolved after millennia of probing? This book looks into the heart of this mystery - at the science and philosophy of consciousness and at many inspiring fictional examples - and finds strange, challenging answers.The book's content and entertaining style will appeal equally to science fiction enthusiasts and scholars, including cognitive and neuroscientists, as well as philosophers of mind. It is a refreshing romp through the science and science fiction of consciousness.