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Cylindrical Vibratory Gyroscope (Springer Tracts in Mechanical Engineering)
by Xuezhong Wu Xiang Xi Yulie Wu Dingbang XiaoThis book introduces readers to the shell structure, operating principle, manufacturing process, and control theory for cylindrical vibratory gyroscopes. The cylindrical vibratory gyroscope is an important type of Coriolis vibratory gyroscope that holds considerable potential for development and application. The main aspects addressed include: operating principle and structure, theoretical analysis and modeling, dynamic analysis and modeling, manufacturing process, parameter testing methods, closed-loop control, and the error compensation mechanism in cylindrical vibratory gyroscopes.
Cyrus Field's Big Dream: The Daring Effort to Lay the First Transatlantic Telegraph Cable
by Mary Morton CowanIn this middle-grade nonfiction title, award-winning author Mary Morton Cowan explores the extraordinary achievement of Cyrus Field and one of the greatest engineering feats of the nineteenth century: laying a transatlantic telegraph cable to create instant communication between two continents. <P><P> Cyrus Field had a big dream to connect North America and Europe with a telegraph line, which would enable instant communication. In the mid-1800s, no one knew if it was possible. That didn’t dissuade Field, who set out to learn about undersea cables and build a network of influential people to raise money and create interest in his project. Field experienced numerous setbacks: many years of delays and failed attempts, millions of dollars lost, suspected sabotage, technological problems, and more. But Field did not give up, ultimately realizing his dream in the summer of 1866. <P><P>Mary Morton Cowan brilliantly captures Field’s life and his steadfast determination to achieve his dream. Back matter includes an author’s note, timeline, bibliography, source notes, and index.
Cyst Nematodes
by Maurice Moens Roland N. Perry Victoria Taylor John T. Jones Godelieve Gheysen Jon Pickup Matthew A. Back James G. Baldwin George W. Bird Vivian C. Blok David J. Chitwood Laura Cortada Matthias Daub Keith G. Davies Walter S. Jong Loes J.M.F. Nijs Sebastian Eves-van Akker Aska Goverse Ivan G. Grove Professor Johannes Hallmann Zafar A. Handoo Catherine J. Lilley Horacio D. Lopez-Nicora Edward P. Masler Melissa G. Mitchum Sharad Mohan Terry L. Niblack Adrian M.I. Roberts Andrea M. Skantar Geert Smant Richard W. Smiley Sergei A Subbotin Gregory L. Tylka Lieven Waeyenberge Inga A. ZasadaThis book is a compendium of current information on all aspects of these economically important parasites. It provides comprehensive coverage of their biology, management, morphology and diagnostics, in addition to up-to-date information on molecular aspects of taxonomy, host-parasitic relationships and resistance. Written by a team of international experts, Cyst Nematodes will be invaluable to all researchers, lecturers and students in nematology, parasitology, agriculture and agronomy, industries with an interest in chemical and biological control products for management of plant-parasitic nematodes, and any courses, quarantine and advisory services.
Cystic Fibrosis: Diagnosis and Protocols, Volume I: Approaches to Study and Correct CFTR Defects (Methods in Molecular Biology #741)
by Karl Kunzelmann Margarida D. AmaralDespite the many milestones in cystic fibrosis (CF) research, progress towards curing the disease has been slow, and it is increasingly difficult to grasp and use the already wide and still growing range of diverse methods currently employed to study CF so as to understand it in its multidisciplinary nature. Cystic Fibrosis: Diagnosis and Protocols aims to provide the CF research community and related researchers with a very wide range of high-quality experimental tools, as an easy way to grasp and use classical and novel methods applied to cystic fibrosis. Volume I: Approaches to Study and Correct CFTR Defects focuses on the cystic fibrosis transmembrane conductance regulator (CFTR) and its expression, biogenesis, structure, and function in terms of the defects causing CF. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Cystic Fibrosis: Diagnosis and Protocols will provide readers with optimal working tools to address pressing questions in the best technical way, while helping all of us, as a research and clinical community, to move faster hand-in-hand toward unravelling the secrets of this challenging disorder and cure it.
Cystic Fibrosis: Diagnosis and Protocols, Volume II: Methods and Resources to Understand Cystic Fibrosis (Methods in Molecular Biology #742)
by Karl Kunzelmann Margarida D. AmaralDespite the many milestones in cystic fibrosis (CF) research, progress toward curing the disease has been slow, and it is increasingly difficult to grasp and use the already wide and still growing range of diverse methods currently employed to study CF so as to understand it in its multidisciplinary nature. Cystic Fibrosis: Diagnosis and Protocols aims to provide the CF research community and related researchers with a very wide range of high-quality experimental tools, as an easy way to grasp and use classical and novel methods applied to cystic fibrosis. Volume II: Methods and Resources to Understand Cystic Fibrosis focuses on pathophysiology, Omics approaches, and a variety of key resources recently made available for CF research. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Cystic Fibrosis: Diagnosis and Protocols will provide readers with optimal working tools to address pressing questions in the best technical way, while helping all of us, as a research and clinical community, to move faster hand-in-hand toward unravelling the secrets of this challenging disorder and cure it.
Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates
by Susanne Radtke-SchullerDescriptionThis stereotaxic atlas of the ferret brain provides detailed architectonic subdivisions of the cortical and subcortical areas in the ferret brain using high-quality histological material stained for cells and myelin together with in vivo magnetic resonance (MR) images of the same animal. The skull-related position of the ferret brain was established according to in vivo MRI and additional CT measurements of the skull. Functional denotations from published physiology and connectivity studies are mapped onto the atlas sections and onto the brain surface, together with the architectonic subdivisions. High-resolution MR images are provided at levels of the corresponding histology atlas plates with labels of the respective brain structures. The book is the first atlas of the ferret brain and the most detailed brain atlas of a carnivore available to date. It provides a common reference base to collect and compare data from any kind of research in the ferret brain.Key Features Provides the first ferret brain atlas with detailed delineations of cortical and subcortical areas in frontal plane. Provides the most detailed brain atlas of a carnivore to date. Presents a stereotaxic atlas coordinate system derived from high-quality histological material and in vivo magnetic resonance (MR) images of the same animal. Covers the ferret brain from forebrain to spinal cord at intervals of 0.6 mm on 58 anterior-posterior levels with 5 plates each. Presents cell (Nissl) stained frontal sections (plate 1) and myelin stained sections (plate 2) in a stereotaxic frame. Provides detailed delineations of brain structures and their denomination on a Nissl stained background on a separate plate (3). Compiles abbreviations on plate 4, a plate that also displays the low resolution MRI of the atlas brain with the outlines of the Nissl sections in overlay. Displays high-resolution MR images at intervals of 0.15 mm from another animal with labeled brain structures as plate 5 corresponding to the anterior-posterior level of each atlas plate. Provides detailed references used for delineation of brain areas. Target audience of the book: The book addresses researchers and students in neurosciences who are interested in brain anatomy in general (e.g., for translational purposes/comparative aspects), particularly those who study the ferret as important animal model of growing interest in neurosciences.
Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling (Advances in Photosynthesis and Respiration #41)
by William A. Cramer Toivo KallasAn Introduction that describes the origin of cytochrome notation also connects to the history of the field, focusing on research in England in the pre-World War II era. The start of the modern era of studies on structure-function of cytochromes and energy-transducing membrane proteins was marked by the 1988 Nobel Prize in Chemistry, given to J. Deisenhofer, H. Michel, and R. Huber for determination of the crystal structure of the bacterial photosynthetic reaction center. An ab initio logic of presentation in the book discusses the evolution of cytochromes and hemes, followed by theoretical perspectives on electron transfer in proteins and specifically in cytochromes. There is an extensive description of the molecular structures of cytochromes and cytochrome complexes from eukaryotic and prokaryotic sources, bacterial, plant and animal. The presentation of atomic structure information has a major role in these discussions, and makes an important contribution to the broad field of membrane protein structure-function.
Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism
by Shufeng ZhouCytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism reviews the current knowledge of CYP2D6 as well as the maturing body of evidence indicating its significance to clinical and pharmacological researchers and practitioners. This book focuses on the critical role CYP2D6 plays in the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural factors of the gene that govern the highly variable metabolism of a number of drugs in clinical use. It highlights the impact of the functional roles of CYP2D6 on clinical practice and drug development and also discusses implications for precise medicine, strategies to avoid adverse drug reactions, and paths for future research. Cytochrome P450 2D6 is a unique, valuable book focusing on a single but immensely powerful human gene. It provides the first single source of comprehensive information on CYP2D6 that serves as an important reference for medical, biomedical, pharmaceutical, and nursing researchers, practitioners, and students.
Cytochrome P450 2E1: Its Role In Disease And Drug Metabolism (Subcellular Biochemistry #67)
by Aparajita DeyThe book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.
Cytochrome P450 Protocols (Methods in Molecular Biology #107)
by Elizabeth A. Shephard Ian R. PhillipsIan Phillips and Elizabeth Shephard assemble a comprehensive collection of cutting-edge techniques and invaluable classic methods for the investigation of cytochromes P450. Described in detail by hands-on experimentalists for easy reproducibility, these methods include spectral analysis, purification and enzymatic assays, expression in heterologous systems, and the production and use of antibodies, as well as methods for quantification of gene expression, transfection of hepatocytes, and for the investigation of DNA-protein interactions and genetic polymorphism. In addition, because of the growing importance of in vitro systems in pharmacological toxicology, the book contains techniques for the culture of rodent and human hepatocytes and human epidermis. Cytochrome P450 induction as a biomarker for environmental pollution and the generation of mice with targeted gene disruptions complete this exhaustive collection of core techniques. Cytochrome P450 Protocols provides both novice and experienced researchers across many fields-toxicology, pharmacology, environmental biology, biochemistry, and molecular biology-all the tools needed to elucidate the crucial biological role played by the cytochromes P450 in the metabolism of therapeutic drugs, chemical carcinogens, and environmental pollutants.
Cytochrome P450 Protocols (Methods in Molecular Biology #320)
by Ian R. PhillipsFor this second edition of their much praised Cytochrome P450, the editors have collected accounts of the essential core techniques that use the latest methodologies for the investigation of P450s. Highlights include protocols for spectral analysis and purification of P450s, enzymatic assays of P450s and flavin-containing monooxygenases (FMOs), expression of P450s and FMOs in heterologous systems, and the production and use of antipeptide antibodies. Additional chapters contain readily reproducible techniques for the transfection of hepatocytes for gene regulation studies, P450 reporter gene assays, in situ hybridization, and analysis of genetic polymorphisms. Although the emphasis is on P450s of mammalian origin, many of the readily reproducible methods described are suitable for P450s from any source.
Cytochrome P450 Protocols (Methods in Molecular Biology #987)
by Elizabeth A. Shephard Ian R. Phillips Paul R. Ortiz de MontellanoCytochromes P450 (CYPs) comprise a large superfamily of proteins that are of central importance in the detoxification or activation of a tremendous number of natural and synthetic hydrophobic xenobiotics, including many therapeutic drugs, chemical carcinogens and environmental pollutants. CYPs are important in mediating interactions between an organism and its chemical environment and in the regulation of physiological processes. Cytochrome P450 Protocols, Third Edition focuses on high-throughput methods for the simultaneous analysis of multiple CYPs, substrates or ligands. Although the emphasis is on CYPs of mammalian origin, it reflects an increasing interest in CYPs of bacterial species. Also included are chapters on cytochrome P450 reductase (the redox partner of CYPs) and the flavin-containing monooxygenases (FMOs), and metabolomic and lipidomic approaches for identification of endogenous substrates of CYPs ('de-orphanizing' CYP substrates). Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Cytochrome P450 Protocols, Third Edition provides a wide range of techniques accessible to researchers in fields as diverse as biochemistry, molecular biology, pharmacology, toxicology, environmental biology and genetics.
Cytochrome P450: In Vitro Methods and Protocols (Methods in Pharmacology and Toxicology)
by Gary W. Caldwell Zhengyin YanThis collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters for individual CYP enzymes, CYP inhibition and induction, time-dependent inhibition (TDI), CYP stability, non-CYP stability, UDP-glucuronosyltransferases (UGT) stability, excretion mechanisms, and drug-drug interactions (DDI), all addressed in this volume. Written for the Methods in Pharmacology and Toxicology series, chapters include helpful background information on the in vitro assay, a list of all the materials, reagents, and equipment necessary to carry out the assay, a step-by-step protocol, notes containing common and unexpected experimental problems in the assay, as well as references containing important supplementary reading. Authoritative and practical, Cytochrome P450: In Vitro Methods and Protocols serves as a key guide for researchers in the area of discovery and development of new medicines.
Cytochrome P450: Structure, Mechanism, and Biochemistry (Methods in Molecular Biology #987)
by Paul R. Ortiz de MontellanoThis authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems. Volume 1 begins with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a discussion of the structures of P450 enzymes and their electron donor partners, the mechanisms of oxygen activation and substrate oxidation, and the approaches and nature of cytochrome P450 inhibition. Two more chapters discuss the nature and roles of cytochrome P450 enzymes in microbes, plants and insects, and an eighth chapter is a survey of the potential utility of P450 enzymes in biotechnology. The first chapter of Volume 2 examines the roles of P450 enzymes in mammals, mainly humans. Four further chapters then deal with the genetic and hormonal regulation of P450 enzymes and their specific roles in the processing of sterols and lipids. Cytochrome P450: Structure, Mechanism, and Biochemistry is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.
Cytogenetic Abnormalities
by S. ZneimerThis guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports. Part one of the guide explores chromosomal, FISH, and microarray analysis in constitutional cytogenetic analyses, while part two looks at acquired abnormalities in cancers. Both sections provide illustrative examples of chromosomal abnormalities and how to communicate these findings in standardized laboratory reports.
Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures
by Susan Mahler ZneimerCytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for laboratory developed tests, and pre-clinical validation study designs. The second focus of the book describes best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides step-wise standard operating procedures for chromosomal, FISH and microarray-based tests, including pre-analytic, analytic and post-analytic steps in testing, and divided into categories by specimen type, and test-type. All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory. Providing both a wealth of information on laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians world-wide in the field of laboratory testing and genetics testing in particular. This book gives the essentials of: Developing and implementing good quality management programs in laboratories Understanding design control of tests and pre-clinical validations studies and reports FDA guidelines for laboratory developed tests Use of reagents, instruments and equipment Cost of testing assessment and process improvement using Six Sigma methodology Staffing training and competency objectives Complete training programs for molecular and cytogenetic technologists Standard operating procedures for all components of chromosomal analysis, FISH and microarray testing of different specimen types This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.
Cytogenetics and Molecular Cytogenetics (Medical Genomics and Proteomics)
by Thomas LiehrGenomic technologies provide the means of diagnosis and management of many human diseases. Without insights from cytogenetics, correct interpretation of modern high-throughput results is difficult, if not impossible. This book summarizes applications of cytogenetics and molecular cytogenetics for students, clinicians and researchers in genetics, genomics and diagnostics. The book combines the state-of-the-art knowledge and practical expertise from leading researchers and clinicians and provides a comprehensive overview of current medical and research applications of many of these technologies. KEY FEATURES • Provides clear summaries of fluorescence in situ hybridization technologies and others • Comprehensively covers established and emerging methods • Chapters from an international team of leading researchers • Useful for students, researchers and clinicians
Cytohistology of Small Tissue Samples
by Lester J. Layfield Carlos W. Bedrossian Julia R. Crim Lucio PalombiniEach volume in this richly illustrated series, sponsored by the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, tabulated specific morphologic criteria and appropriate ancillary testing algorithms. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume describes the cytologic, small core biopsy, immunohistochemical and molecular diagnostic features of musculoskeletal lesions. It provides the cytopathologist and histopathologist with a comprehensive survey of diagnostic approaches and diagnostic features for benign and malignant lesions. Each chapter contains a detailed summary of differential diagnostic features, supported by high-quality images and case studies. The print edition includes a CD-ROM offering all images in a downloadable format. With over 500 photomicrographs, this is an important resource for practising pathologists and residents in pathology.
Cytokine Gene Polymorphisms in Multifactorial Conditions
by Koen VandenbroeckThe literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism
Cytokine Inhibitors
by Gennaro Ciliberto Rocco SavinoCompiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of
Cytokine Protocols (Methods in Molecular Biology #249)
by Marc De LeyA collection of biochemical, cellular, and molecular techniques for unraveling and quantifying the events occurring between the initial contact of a cytokine at the membrane receptor and the eventual activation of gene transcription. The techniques used include the generation of transfectants, the immunohistochemical detection of cytokines in tissue sections, and optimized staining for cytoplasmic detection. Highlights include RT-PCR of small amounts of mRNA, in situ hybridization, biosensor analysis, measurement of biological activities and standardization, immunohistochemical and single-cell detection, and receptor isolation, characterization, and crystallization.
Cytokine Protocols, 2nd Edition (Methods in Molecular Biology #820)
by Marc De LeyRecent studies have discovered new known and characterized cytokines, allowing for advancement in miniaturization of micro-analytical methods as well as the extensive development of bio-informatics and nanotechnology. These advancements have allowed researchers to reduces sample sizes making for more accurate determinations then previously possible. In Cytokine Protocols: Second Edition, expert researchers in the field detail many of the methods which are now commonly used to study cytokines. These methods and techniques for studying cytokines include historical importance and the importance of researchers using bioassay, quantification, and characterization of cytokine related RNAs, posttranscriptional modifications of RNA, either naturally or artificially, and observations at the protein level. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.<P> Authoritative and practical, Cytokine Protocols: Second Edition seeks to aid scientists in furthering the crucially important advancement of cytokine research
Cytokine Storm Syndrome
by Randy Q. Cron Edward M. BehrensCytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals.A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.
Cytokine Storm Syndrome (Advances in Experimental Medicine and Biology #1448)
by Randy Q. Cron Edward M. BehrensCytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This second edition addresses all aspects of the disorder, from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors and treatment. New-to-this-edition features include dedicated chapters on severe COVID-19 CSS, and post-COVID CSS of multi-system inflammatory syndrome in children (MIS-C). In addition, novel topics including CSS associated with Castleman disease, pregnancy, therapeutics, transplantation, and cardiac bypass, as well as treatment with JAK inhibitors are addressed.
Cytokines and Cytokine Receptors: Physiology and Pathological Disorders
by Constantin A. Bona Jean-Pierre RevillardThe field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of