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Filaggrin
by Jacob P. Thyssen Howard I. MaibachFilaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major predisposing factors for related asthma and hay fever. This textbook provides comprehensive and detailed coverage of the effects of FLG mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
Filamentary Ion Flow: Theory and Experiments
by Vitantonio Amoruso Francesco LattaruloPresents all-new laboratory-tested theory for calculating more accurate ionized electric fields to aid in designing high-voltage devices and its components Understanding and accurately calculating corona originated electric fields are important issues for scientists who are involved in electromagnetic and electrostatic studies. High-voltage dc lines and equipment, in particular, can generate ion flows that can give rise to environmental inconveniences. Filamentary Ion Flow: Theory and Experiments provides interdisciplinary theoretical arguments to attain a final model for computational electrostatics in the presence of flowing space charge. Based on years of extensive lab tests pertaining to the physical performance of unipolar corona ion flows, the book covers the enlarging of conventional electrostatic applications, which allows for some emerging and uncharted interests to be explored. Filamentary Ion Flow: Examines the theoretical discussions for creating a model of computational electrostatics involved with flowing space charges Presents new theory and experimental data based on extensive testing Offers potential design applications utilizing the theory Helps scientists who are involved in electromagnetic and electrostatic studies understand and accurately calculate corona originated ion flow fields Filamentary Ion Flow: Theory and Experiments is ideal for electrical engineers and research scientists interested in high-voltage technology, computational electrostatics, and electromagnetic theory.
Filaments in Bioprocesses
by Rainer Krull Thomas BleyThis book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Filling and Wrapping: Three-Dimensional Measurement
by Glenda Lappan Elizabeth Difanis Phillips James T. Fey Susan N. FrielNIMAC-sourced textbook
Filling and Wrapping, Three-Dimensional Measurement
by Glenda Lappan James T. Fey William M. Fitzgerald Susan N. Friel Elizabeth Difanis PhillipsNIMAC-sourced textbook
La Filosofía en 100 preguntas (100 Preguntas esenciales)
by Vicente Caballero de la TorreLos temas clave para sumergirse en el apasionante y complejo mundo de la Filosofía, ordenados por temas y descritos con rigor académico en un lenguaje ameno y divulgativo. ¿Qué es la Filosofía?, metafísica, ontología, los límites del conocimiento, el hombre en el cosmos, filosofía de la religión, filosofía y economía, sociedad y política, arte y estética. Todas las respuestas a las preguntas que siempre se ha hecho. ¿Sabías que la filosofía oriental está tan de moda porque vivimos en tiempos de crisis?, ¿Existe Dios o nos lo hemos inventado?, ¿Cómo podemos distinguir las paraciencias de las ciencias?, ¿Qué quiso decir Descartes con su «Pienso, luego existo»?, ¿Tenemos un cuerpo o somos nuestro cuerpo?, ¿Somos realmente libres o la libertad es una ilusión?, ¿Se pueden educar las emociones?, ¿Necesitamos realmente vivir en sociedad o estaríamos mejor en soledad?, ¿Será posible la paz para siempre?, ¿Sabías que los economistas discuten más por Filosofía que por Economía?, ¿Hay una belleza objetiva o cualquier cosa puede ser bella para alguien y fea para otro?
Filosofía natural: Una historia de nuestras ideas sobre la naturaleza
by Paul FeyerabendUna historia de nuestras ideas sobre la naturaleza desde la Edad de Piedra hasta la era de la física cuántica. La obra póstuma de Paul Feyerabend, uno de los filósofos más importantes del siglo XX. Paul Feyerabend fue uno de los científicos más originales y controvertidos de su tiempo. Su «todo vale» se ha convertido en un lema, y la claridad en la exposición de sus ideas atrajo al público dentro y fuera de las universidades. Filosofía natural pretende reconstruir la historia de las concepciones humanas de la naturaleza desde sus primeras expresiones en las pinturas rupestres de la Edad de Piedra hasta las discusiones del siglo XX sobre física nuclear. Publicada con más de treinta años de retraso, fue concebida originalmente como una obra en tres tomos que nunca llegaron a escribirse. El manuscrito se dio por perdido durante mucho tiempo, hasta que una copia mecanografiada apareció en los archivos de la Universidad de Constanza. Paul Feyerabend examina el significado de los mitos desde los albores de la filosofía natural hasta Parménides, y centra sus reflexiones en el crecimiento devastador del racionalismo durante la antigüedad griega y la consecuente separación del hombre y la naturaleza. Reseña:«El texto póstumo de Paul Feyerabend animará a buscar una nueva interpretación de la naturaleza y una mejor forma de vivir.»Neue Zürcher Zeitung
Filter Banks and Audio Coding: Compressing Audio Signals Using Python
by Gerald SchullerThis textbook presents the fundamentals of audio coding, used to compress audio and music signals, using Python programs both as examples to illustrate the principles and for experiments for the reader. Together, these programs then form complete audio coders. The author starts with basic knowledge of digital signal processing (sampling, filtering) to give a thorough introduction to filter banks as used in audio coding, and their design methods. He then continues with the next core component, which are psycho-acoustic models. The author finally shows how to design and implement them. Lastly, the author goes on to describe components for more specialized coders, like the Integer-to-Integer MDCT filter bank, and predictive coding for lossless and low delay coding. Included are Python program examples for each section, which illustrate the principles and provide the tools for experiments.Comprehensively explains the fundamentals of filter banks and audio coding;Provides Python examples for each principle so that completed audio coders are obtained in the language;Includes a suite of classroom materials including exercises, experiments, and examples.
Filterbänke und Audiocodierung: Komprimierung von Audiosignalen mit Python
by Gerald SchullerDieses Lehrbuch stellt die Grundlagen der Audiocodierung vor, die zur Komprimierung von Audio- und Musiksignalen verwendet wird. Dabei werden Python-Programme sowohl als Beispiele zur Veranschaulichung der Prinzipien als auch für Experimente für den Leser verwendet. Zusammen bilden diese Programme dann komplette Audiocodierer. Der Autor beginnt mit grundlegenden Kenntnissen der digitalen Signalverarbeitung (Abtastung, Filterung), um eine gründliche Einführung in Filterbänke, wie sie in der Audiocodierung verwendet werden, und deren Entwurfsmethoden zu geben. Er fährt dann mit der nächsten Kernkomponente fort, den psycho-akustischen Modellen. Der Autor zeigt schließlich, wie man sie entwirft und implementiert. Schließlich beschreibt der Autor Komponenten für speziellere Kodierer, wie die Integer-to-Integer MDCT-Filterbank und prädiktive Kodierung für verlustfreie und verzögerungsarme Kodierung. Zu jedem Abschnitt gibt es Python-Programmbeispiele, die die Prinzipien veranschaulichen und die Werkzeuge für Experimente bereitstellen. Umfassende Erläuterung der Grundlagen von Filterbänken und Audiocodierung; Bietet Python-Beispiele für jedes Prinzip, so dass fertige Audiocodierer in der Sprache erhalten werden; Enthält eine Reihe von Unterrichtsmaterialien mit Übungen, Experimenten und Beispielen.
Filtered Repetitive Control with Nonlinear Systems
by Quan Quan Kai-Yuan CaiThough there have been significant advances in the theory and applications of linear time-invariant systems, developments regarding repetitive control have been sporadic. At the same time, there is a dearth of literature on repetitive control (RC) for nonlinear systems.Addressing that gap, this book discusses a range of basic methods for solving RC problems in nonlinear systems, including two commonly used methods and three original ones. Providing valuable tools for researchers working on the development of repetitive control, these new and fundamental methods are one of the major features of the book, which will benefit researchers, engineers, and graduate students in e.g. the field of control theory.
Filtering and Control for Classes of Two-Dimensional Systems
by Ligang Wu Zidong WangThis book focuses on filtering, control and model-reduction problems for two-dimensional (2-D) systems with imperfect information. The time-delayed 2-D systems covered have system parameters subject to uncertain, stochastic and parameter-varying changes. After an initial introduction of 2-D systems and the ideas of linear repetitive processes, the text is divided into two parts detailing: · General theory and methods of analysis and optimal synthesis for 2-D systems; and · Application of the general theory to the particular case of differential/discrete linear repetitive processes. The methods developed provide a framework for stability and performance analysis, optimal and robust controller and filter design and model approximation for the systems considered. Solutions to the design problems are couched in terms of linear matrix inequalities. For readers interested in the state of the art in linear filtering, control and model reduction, Filtering and Control for Classes of Two-Dimensional Systems will be a useful reference for exploring the field of 2-D systems either from a purely theoretical research perspective or from the point of view of a multitude of potential applications including image processing, and the study of seismographic data or thermal processes.
Filtering and System Identification
by Michel Verhaegen Vincent VerdultFiltering and system identification are powerful techniques for building models of complex systems. This 2007 book discusses the design of reliable numerical methods to retrieve missing information in models derived using these techniques. Emphasis is on the least squares approach as applied to the linear state-space model, and problems of increasing complexity are analyzed and solved within this framework, starting with the Kalman filter and concluding with the estimation of a full model, noise statistics and state estimator directly from the data. Key background topics, including linear matrix algebra and linear system theory, are covered, followed by different estimation and identification methods in the state-space model. With end-of-chapter exercises, MATLAB simulations and numerous illustrations, this book will appeal to graduate students and researchers in electrical, mechanical and aerospace engineering. It is also useful for practitioners. Additional resources for this title, including solutions for instructors, are available online at www. cambridge. org/9780521875127.
Filtering Media by Electrospinning: Next Generation Membranes For Separation Applications
by Seeram Ramakrishna Chiara Gualandi Maria Letizia FocareteThis book covers the state-of-the-art on electrospun materials for the use of filters for water remediation, ion-exchange membranes and affinity membranes for the capture of selected chemical and biochemical species, as well as filtering applications covering air treatment, defense and protective applications, and oil-water separation. The book also provides an overview of the landscape of marketed electrospun filters and of technical approaches for the large scale production of nanofibrous non-woven filter media. This is an ideal book for biomaterials and polymer researchers interested in the applications of filtering media by electrospinning.This book also:Covers the latest research on ion-exchange membranes and affinity membranes for capture of cells and biological substancesBroadens reader understanding of antimicrobial electrospun filters and sieving filters for liquid microfiltrationReviews exhaustively the key recent research into electrospun filters for oil-water separation, heavy metals removal, and defense and protective applications
Filtration: Principles and Practices, Second Edition, Revised and Expanded
by MattesonCompletely revised and updated, this Second Edition of the critically acclaimed referenceprovides the very latest theoretical and practical data on filtration of gases and liquids.Filtration: Principles and Practices, Second Edition, Revised and Expanded features severalall-new chapters which detail filtration in the mineral industry, high-efficiency air filtration,cartridge filters, and ultrafiltration.The most authoritative and comprehensive guide to essential, state-of-the-art data, Filtration:Principles and Practices, Second Edition, Revised and Expanded is an indispensable referencefor industrial process and chemical engineers and scientists engaged in research, development,and production in the chemical, mineral, food, beverage, and pharmaceutical industries. Itis also a valuable reference for upper-level undergraduate and graduate students in chemicalengineering courses in unit operations.
Filtration and Purification in the Biopharmaceutical Industry, Third Edition (Drugs and the Pharmaceutical Sciences)
by Maik W. JornitzSince sterile filtration and purification steps are becoming more prevalent and critical within medicinal drug manufacturing, the third edition of Filtration and Purification in the Biopharmaceutical Industry greatly expands its focus with extensive new material on the critical role of purification and advances in filtration science and technology. It provides state-of-the-science information on all aspects of bioprocessing including the current methods, processes, technologies and equipment. It also covers industry standards and regulatory requirements for the pharmaceutical and biopharmaceutical industries. The book is an essential, comprehensive source for all involved in filtration and purification practices, training and compliance. It describes such technologies as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration. Features: Addresses recent biotechnology-related processes and advanced technologies such as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration of medium, buffer and end product Presents detailed updates on the latest FDA and EMA regulatory requirements involving filtration and purification practices, as well as discussions on best practises in filter integrity testing Describes current industry quality standards and validation requirements and provides guidance for compliance, not just from an end-user perspective, but also supplier requirement It discusses the advantages of single-use process technologies and the qualification needs Sterilizing grade filtration qualification and process validation is presented in detail to gain the understanding of the regulatory needs The book has been compilated by highly experienced contributors in the field of pharmaceutical and biopharmaceutical processing. Each specific topic has been thoroughly examined by a subject matter expert.
Fimbriae Adhesion, Genetics, Biogenesis, and Vaccines
by Per KlemmFimbriae are the best-studied bacterial colonization factors. They are of paramount importance in bacterial pathogenesis and microbial ecology. Due to the advent of new and powerful techniques, an impressive amount of information has been accumulated on these important surface organelles over the last decade. The first book of its kind, Fimbriae brings together into one volume the state of the art of this very active field. Internationally recognized researchers give both a horizontal and lateral approach to fimbriology. Selected types of fimbriae are extensively reviewed and fundamental questions such as evolution, control or regulation, biogenesis, bacteria-host interaction, and fimbriae-based vaccines are examined.
El fin de la ciencia: Todo Lo Que Un Ciudadano Debe Saber Sobre Ciencia Y No Sabe Cómo Preguntar Ni De
by Manuel Lozano LeyvaTodo lo que un ciudadano (que no sabe qué preguntar ni de quién fiarse) debería saber sobre ciencia. El fin de la ciencia responde a una doble pregunta: ¿se puede acabar la ciencia? y ¿qué busca la ciencia? Tras un irreverente recorrido por la historia de la ciencia y la tecnología, el prestigioso científico y gran divulgador Lozano Leyva realiza un ameno e inteligente recorrido por los riesgos y las amenazas actuales, desde la mediocridad y la falta de recursos hasta las pseudociencias o el negacionismo ambiental, para repasar a continuación sus objetivos en los campos más diversos. La idea de partida del libro es que los ciudadanos no pueden ejercer la democracia apropiadamente sin unos conocimientos básicos de lo que es la ciencia y la tecnología, incluidos no sólo sus grandezas y milagros, sino también sus miserias y peligros. La expansión del conocimiento científico y técnico que arrancó en el Renacimiento,tomó impulso en la Ilustración y eclosionó con las grandes y sangrientas convulsiones del siglo XX es un fenómeno único en la historia al que nos tenemos que enfrentar en el siglo XXI. Lo hemos de hacer ilusionados, sí, pero también alertas. Y nuestros políticos saben de esto lo mismo que los ciudadanos: poco o nada. Esclarecer esas ideas, o contribuir a hacerlo, es lo que pretende El fin de la ciencia. «Lo único que quiero con este libro es que cualquier persona tenga una razón más para meter un voto en la urna.»Manuel Lozano Leyva Reseña:«El fin de la ciencia se ocupa, principalmente, de revelar errores de juicio, supercherías notorias y campos donde la ciencia será decisiva en un futuro inmediato: la pesca, la alimentación, el suministro de agua, la prevención y el combate de enfermedades endémicas, etc.»Diario de Sevilla
El fin de la ciencia
by Manuel Lozano LeyvaEl fin de la ciencia es la respuesta a una doble pregunta: ¿se puede acabar la ciencia? y ¿qué busca la ciencia? Tras un irreverente recorrido por la historia de la ciencia y la tecnología, el prestigioso científico y gran divulgador Lozano Leyva realiza un ameno e inteligente recorrido por los riesgos y amenazas actuales, desde la mediocridad y la falta de recursos hasta las pseudo ciencias o el negacionismo ambiental, para a continuación repasar sus objetivos en los campos más diversos. Porque la idea de partida del libro es que los ciudadanos no pueden ejercer la democracia apropiadamente sin unos conocimientos básicos de lo que es la ciencia y la tecnología, incluidos no sólo sus grandezas y milagros sino también sus miserias y peligros. La expansión del conocimiento científico y técnico que arrancó en el Renacimiento, tomó impulso en la Ilustración y eclosionó con las grandes y sangrientas convulsiones del siglo XX es un fenómeno único en la historia al que nos tenemos que enfrentar en el siglo XXI. Lo hemos de hacer ilusionados, sí, pero también alertas. Y nuestros políticos saben de esto lo mismo que los ciudadanos: poco o nada. Esclarecer esas ideas, o contribuir a hacerlo, es lo que pretende El fin de la ciencia.
Final Comments on the Science Plan for the North Pacific Research Board
by National Research Council of the National AcademiesThe North Pacific Research Board (NPRB) was established by Congress in 1997 to recommend marine research activities to the Secretary of Commerce on or relating to the fisheries or marine ecosystem in the North Pacific Ocean, Bering Sea, Arctic Ocean, and related bodies of water. NPRB called on the National Academies to develop a comprehensive long range science plan pertaining to its research activities. This assistance has been provided in two phases. In phase one, beginning in early 2003, a National Academies committee worked to understand the purpose of the NPRB, gather information to help identify research needs, and provide advice on the components of a sound science plan. The committee's assessment is contained in a report released in early 2004, Elements of a Science Plan for the North Pacific Research Board. With this guidance as a tool, the NPRB staff, Science Panel, and Advisory Panel worked together to write a draft science plan to steer the program in the coming decade. During the second phase, the same committee reviewed the NPRB's draft science plan and provided final feedback to the NPRB. It is a focused review, generally following the organization of the NPRB document. This report is intended primarily as a direct communication from the committee to those planning the NPRB's programs, to help them improve the science plan and ensure successful implementation.
Final Report of the Committee on a Strategic Plan for U.S. Burning Plasma Research
by National Academies of Sciences Engineering MedicineFusion offers the prospect of virtually unlimited energy. The United States and many nations around the world have made enormous progress toward achieving fusion energy. With ITER scheduled to go online within a decade and demonstrate controlled fusion ten years later, now is the right time for the United States to develop plans to benefit from its investment in burning plasma research and take steps to develop fusion electricity for the nation’s future energy needs. At the request of the Department of Energy, the National Academies of Sciences, Engineering, and Medicine organized a committee to develop a strategic plan for U.S. fusion research. The final report’s two main recommendations are: (1) The United States should remain an ITER partner as the most cost-effective way to gain experience with a burning plasma at the scale of a power plant. (2) The United States should start a national program of accompanying research and technology leading to the construction of a compact pilot plant that produces electricity from fusion at the lowest possible capital cost.
A Final Story: Science, Myth, and Beginnings
by Nasser ZakariyaPopular science readers embrace epics—the sweeping stories that claim to tell the history of all the universe, from the cosmological to the biological to the social. And the appeal is understandable: in writing these works, authors such as E. O. Wilson or Steven Weinberg deliberately seek to move beyond particular disciplines, to create a compelling story weaving together natural historical events, scientific endeavor, human discovery, and contemporary existential concerns. In A Final Story, Nasser Zakariya delves into the origins and ambitions of these scientific epics, from the nineteenth century to the present, to see what they reveal about the relationship between storytelling, integrated scientific knowledge, and historical method. While seeking to transcend the perspectives of their own eras, the authors of the epics and the debates surrounding them are embedded in political and social struggles of their own times, struggles to which the epics in turn respond. In attempts to narrate an approach to a final, true account, these synthesizing efforts shape and orient scientific developments old and new. By looking closely at the composition of science epics and the related genres developed along with them, we are able to view the historical narrative of science as a form of knowledge itself, one that discloses much about the development of our understanding of and relationship to science over time.
Finance and Accounting for Energy Engineers: & Engineers in All Disciplines (River Publishers Series in Energy Management)
by S. Bobby RaufThe purpose of this second edition is to provide an overview of important principles in the fields of finance and accounting, and the application of those principles for financial analysis of energy and non-energy capital investments. This book is written as a self-study guide for energy and non-energy engineers and managers who either lack formal training in the subjects of finance, accounting, and engineering economics, or simply need a means to refresh their knowledge in these subjects. This book bridges the gap between the typical business school "MBA" knowledge and its application in enery and non-engergy engineering, project management or manufacturing management. Many energy and non-energy engineers and technical managers feel inadequately equipped to comprehend and apply certain important finance and accounting principles. Understanding of finance and accounting principles is important in interfacing and conducting business with accountants, financial analysts, and members of upper management. This book is designed to familiarize energy engineers and other engineering professionals - in a relatively simple and easy to understand fashion - with decision making skills founded on financial calculations and case study based quantitative analysis.
Financial Crimes: A Threat to Global Security (Advances in Police Theory and Practice)
by Maximillian Edelbacher Peter Kratcoski Michael TheilFinancial market reform has focused chiefly on the threats to stability arising from the risky, uncontrolled activity of the leaders of financial institutions. Nevertheless, organized crime, white-collar crime, and corruption have a huge impact on financial systems worldwide and must also be confronted if true reform is to be achieved. A collection
Financial Crimes: A Threat to Global Security
by Maximillian Edelbacher, Peter Kratcoski and Michael TheilFinancial market reform has focused chiefly on the threats to stability arising from the risky, uncontrolled activity of the leaders of financial institutions. Nevertheless, organized crime, white-collar crime, and corruption have a huge impact on financial systems worldwide and must also be confronted if true reform is to be achieved. A collection
Financial Crimes and Existential Philosophy
by Michel DionThe aim of this book is to deepen our understanding of financial crimes as phenomena. It uses concepts of existential philosophies that are relevant to dissecting the phenomenon of financial crimes. With the help of these concepts, the book makes clear what the impact of financial crimes is on the way a human being defines himself or the way he focuses on a given notion of humankind. The book unveils how the growth of financial crimes has contributed to the increase of the anthropological gap, and how the phenomenon of financial crimes now distorts the way we understand humankind. Using the existential philosophies of Kierkegaard, Nietzsche, Jaspers, Buber, Heidegger, and Marcel, the book sheds light on how these philosophies can help to better perceive and describe financial crimes. Next it looks at prevention strategies from an organizational perspective, using concepts of Sartre, Gadamer and Tillich. The book provides readers with existential principles that will help them be more efficient when they have to design and implement prevention strategies against corporate crime.