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From the Web to the Grid and Beyond
by René Brun Giuliana Galli Carminati Federico CarminatiBorn after World War II, large-scale experimental high-energy physics (HEP) has found itself limited ever since by available accelerator, detector and computing technologies. Accordingly, HEP has made significant contributions to the development of these fields, more often than not driving their innovations. The invention of the World Wide Web at CERN is merely the best-known example out of many. This book is the first comprehensive account to trace the history of this pioneering spirit in the field of computing technologies. It covers everything up to and including the present-day handling of the huge demands imposed upon grid and distributed computing by full-scale LHC operations--operations which have for years involved many thousands of collaborating members worldwide and accordingly provide the original and natural testbed for grid computing concepts. This book takes the reader on a guided tour encompassing all relevant topics, including programming languages, software engineering, large databases, the Web, and grid- and cloud computing. The important issue of intellectual property regulations for distributed software engineering and computing is also addressed. Aptly, the book closes with a visionary chapter of what may lie ahead. Approachable and requiring only basic understanding of physics and computer sciences, this book is intended for both education and research.
Frontier Discoveries and Innovations in Interdisciplinary Microbiology
by Pratyoosh ShuklaThis excellent book covers wide-ranging topics in interdisciplinary microbiology, addressing various research aspects and highlighting advanced discoveries and innovations. It presents the fascinating topic of modern biotechnology, including agricultural microbiology, microalgae biotechnology, bio-energy, bioinformatics and metagenomics, environmental microbiology, enzyme technology and marine biology. It presents the most up-to-date areas of microbiology with an emphasis on shedding light on biotechnological advancements and integrating these interdisciplinary microbiology research topics into other biotechnology sub-disciplines. The book raises awareness of the industrial relevance of microbiology, which is key component of this unique collection. The topics include production of antioxidant-glutathione, enzyme-engineering methods, probiotic microbiology and features of microbial xylanases. It also covers some other remarkable aspects of microbiology, like potential health hazards in recreational water and fullerene nanocomposites, which are vital for biotechnological interventions. This book will be valuable resource for senior undergraduate and graduate students, researchers and other interested professionals or groups working in the interdisciplinary areas of microbiology and biotechnology.
Frontier Science: Northern Canada, Military Research, and the Cold War, 1945–1970
by Matthew WisemanBetween 1945 and 1970, Canada’s Department of National Defence sponsored scientific research into the myriad challenges of military operations in cold regions. To understand and overcome the impediments of the country’s cold climate, scientists studied cold-weather acclimatization, hypothermia, frostbite, and psychological morale for soldiers assigned to active duty in northern Canada. Frontier Science investigates the history of military science in northern Canada during this period of the Cold War, highlighting the consequences of government-funded research for humans and nature alike. The book reveals how under the guise of “environmental protection” research, the Canadian military sprayed pesticides to clear bushed areas, used radioactive substances to investigate vector-borne diseases, pursued race-based theories of cold tolerance, and enabled wide-ranging tests of newly developed weapons and equipment. In arguing that military research in northern Canada was a product of the Cold War, Matthew S. Wiseman tackles questions of government power, scientific authority, and medical and environmental research ethics. Based on a long and deep pursuit of declassified records, archival sources, and oral testimony, Frontier Science is a fascinating new history of military approaches to the human-nature relationship.
Frontier Studies in Soil Science (Frontier Studies in Soil Science)
by Avelino Núñez-DelgadoThis is the first book where top researchers focus on presenting new research proposals in soil science. All the authors contributing to the book have a solid background and experience in specific fields of soil science, allowing them to propose the critical lines of future development in their respective and particular paths of cut-edge investigation. The primary audiences for the work are scientists/researchers working in these fields, as well as students interested in the views from top scientists on recent and future trends in the area, and all those in the overall society desiring to be aware of possible pathways for the future of soil science.
Frontier Technologies for Crop Improvement (Sustainability Sciences in Asia and Africa)
by Rajeev K. Varshney Manish Roorkiwal Manish K. Pandey Alison Bentley Haile DesmaeThis edited book is a compilation of information on existing frontier technologies in agriculture, such as driving modernized crop improvement programs via digitalization, mechanization and automation, artificial intelligence, speed breeding. The major focus of the book is on the technologies related to genetic gain, nutrition and food safety. Agriculture is core to industry as well as human civilization and sustainability of the society. Therefore, advancement and investment of technology is essential for enhancing the quality and quantity of the produce for ensuring food and nutritional security. The frontier technologies bring drastic change in the way of functioning leading to multi-fold increase in efficiency and outcome. Chapters in this book addresses a particular enabling technology and forward-looking strategy. Compiled information with successful deployment examples of these technologies is not been made available from a single platform, therefore, this volume is a unified compilation of information from international experts. The book is a relevant reading material for students, researchers, academicians and industry players in agriculture.
Frontier Technologies in Bovine Reproduction
by A. Kumaresan A. K. SrivastavaThis book details the frontier technologies in the area of bovine reproduction. It describes the importance and significance of different technologies for improving reproduction efficiency in bovines. The book delineates the advancements in the technologies that are currently in use for faster multiplication of elite germ plasm including multiple ovulation and embryo transfer, ovum-pick-up, in vitro fertilization and embryo production, and semen sexing. Other emerging technologies, having potential for improving reproductive efficiency in bovines, including stem cells are also discussed with special reference to spermatogonial stem cells. Simple but effective tools having a great scope for day-to-day application in bovine farms for effective reproductive management like ultrasonography and thermal imaging are also covered in this book. The chapters on sperm transcriptomics, proteomics, metabolomics provide current developments in these areas and use of integrated approach for identification of fertility biomarkers. The chapters also describe technological advancements for early pregnancy diagnosis and offspring sex pre-selection in bovines. Additionally, this book discusses different sperm selection procedures including application of nanotechnology to obtain superior spermatozoa for assisted reproduction. Futuristic technologies including genomic selection and transgenesis are also discussed in detail. Finally, the book also elucidates a comprehensive description of challenges perceived with bovine reproduction and how effectively these technologies can help in improving fertility in bovines.
Frontiers and Challenges in Warm Dense Matter
by Frank Graziani Michael P. Desjarlais Ronald Redmer Samuel B. TrickeyWarm Dense Matter (WDM) occupies a loosely defined region of phase space intermediate between solid, liquid, gas, and plasma, and typically shares characteristics of two or more of these phases. WDM is generally associated with the combination of strongly coupled ions and moderately degenerate electrons, and careful attention to quantum physics and electronic structure is essential. The lack of a small perturbation parameter greatly limits approximate attempts at its accurate description. Since WDM resides at the intersection of solid state and high energy density physics, many high energy density physics (HEDP) experiments pass through this difficult region of phase space. Thus, understanding and modeling WDM is key to the success of experiments on diverse facilities. These include the National Ignition Campaign centered on the National Ignition Facility (NIF), pulsed-power driven experiments on the Z machine, ion-beam-driven WDM experiments on the NDCX-II, and fundamental WDM research at the Linear Coherent Light Source (LCLS). Warm Dense Matter is also ubiquitous in planetary science and astrophysics, particularly with respect to unresolved questions concerning the structure and age of the gas giants, the nature of exosolar planets, and the cosmochronology of white dwarf stars. In this book we explore established and promising approaches to the modeling of WDM, foundational issues concerning the correct theoretical description of WDM, and the challenging practical issues of numerically modeling strongly coupled systems with many degrees of freedom.
Frontiers and Progress in Multiphase Flow I
by Lixin ChengThis volume presents state-of-the-art of reviews in the field of multiphase flow. In focusses on nonlinear aspects of multiphase flow networks as well as visualization experiments. The first chapter presents nonlinear aspects or deterministic chaos issues in the systems of multi-phase reactors. The second chapter reviews two-phase flow dynamics in combination with complex network theory. The third chapter discusses evaporation mechanism in the wick of copper heat pipes. The last chapter investigates numerically the flow dynamics and heat and mass transfer in the laminar and turbulent boundary layer on the flat vertical plate.
Frontiers and Progress of Current Soft Matter Research (Soft and Biological Matter)
by Xiang-Yang LiuThis book covers some fundamental aspects and frontiers in non-equilibrium physics and soft matter research. Apart from the basic knowledge on nonlinear statistic physics, dynamics, computer simulations, and main approaches and emerging systems in soft matter research, particular attention is devoted to new conceptual flexible functional materials and the enriching areas, such as silk meso-molecular materials, molecular gels, liquid crystals, flexible electronics and new types of catalysis, etc. One of the main characteristics of this book is to start with the structure formation dynamics and the correlation between the structures and macroscopic performance. This lays down the foundation for the mesoscopic materials design and functionalization. The book is intended for upper undergraduate students, graduate students, and researchers who are interested in soft matter researches. As one of main references, the basic principles and technologies of computer simulations and experimental methods adopted in soft matter research are also explained. Illustrations and tables are included in this book to improve the readability, and examples and exercises are added to help understanding.
Frontiers in Biophotonics for Translational Medicine
by Malini Olivo U. S. DinishThe present book provides recent developments in various in vivo imaging and sensing techniques such as photo acoustics (PA) imaging and microscopy, ultrasound-PA combined modalities, optical coherence tomography (OCT) and micro OCT, Raman and surface enhanced Raman scattering (SERS), Fluorescence lifetime imaging (FLI) techniques and nanoparticle enabled endoscopy etc. There is also a contributing chapter from leading medical instrumentation company on their view of optical imaging techniques in clinical laparoscopic surgery. The UN proclaimed 2015 as the International Year of Light and Light-based Technologies, emphasizing achievements in the optical sciences and their importance to human beings. In this context, this book focusses on the recent advances in biophotonics techniques primarily focused towards translational medicine contributed by thought leaders who have made cutting edge developments in various photonics techniques.
Frontiers in Computational Fluid-Structure Interaction and Flow Simulation: Research From Lead Investigators Under Forty - 2018 (Modeling and Simulation in Science, Engineering and Technology)
by Tayfun E. TezduyarComputational fluid-structure interaction and flow simulation are challenging research areas that bring solution and analysis to many classes of problems in science, engineering, and technology. Young investigators under the age of 40 are conducting much of the frontier research in these areas, some of which is highlighted in this book. The first author of each chapter took the lead role in carrying out the research presented. The topics covered include Computational aerodynamic and FSI analysis of wind turbines,Simulating free-surface FSI and fatigue-damage in wind-turbine structural systems,Aorta flow analysis and heart valve flow and structure analysis,Interaction of multiphase fluids and solid structures,Computational analysis of tire aerodynamics with actual geometry and road contact, andA general-purpose NURBS mesh generation method for complex geometries.This book will be a valuable resource for early-career researchers and students — not only those interested in computational fluid-structure interaction and flow simulation, but also other fields of engineering and science, including fluid mechanics, solid mechanics and computational mathematics – as it will provide them with inspiration and guidance for conducting their own successful research. It will also be of interest to senior researchers looking to learn more about successful research led by those under 40 and possibly offer collaboration to these researchers.
Frontiers in Computational and Systems Biology
by Jianfeng Feng Wenjiang Fu Fengzhu SunThis unique volume surveys state-of-the-art research on statistical methods in molecular and systems biology, with contributions from leading experts in the field. Each chapter discusses theoretical aspects, applications to biological problems, and possible future developments. Topics and features: presents the use of thermodynamic models to analyze gene regulatory mechanisms; reviews major algorithms for RNA secondary structure prediction; discusses developments in the area of oligo arrays; examines the application of models of stochastic processes in nonequilibrium thermodynamics and biological signal transduction; describes phylogenetic footprinting methods for TFBS identification; introduces penalized regression-based methods for constructing genetic interaction or regulatory networks; investigates the specific role played by irreversible Markov processes in modeling cellular biochemical systems; explores the concept of gene modules in a transcriptional regulatory network.
Frontiers in Crystalline Matter: From Discovery to Technology
by National Research Council of the National AcademiesFor much of the past 60 years, the U.S. research community dominated the discovery of new crystalline materials and the growth of large single crystals, placing the country at the forefront of fundamental advances in condensed-matter sciences and fueling the development of many of the new technologies at the core of U.S. economic growth. The opportunities offered by future developments in this field remain as promising as the achievements of the past. However, the past 20 years have seen a substantial deterioration in the United States' capability to pursue those opportunities at a time when several European and Asian countries have significantly increased investments in developing their own capacities in these areas. This book seeks both to set out the challenges and opportunities facing those who discover new crystalline materials and grow large crystals and to chart a way for the United States to reinvigorate its efforts and thereby return to a position of leadership in this field.
Frontiers in Developmental Biology (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine)
by Robert A. MeyersThis topical volume in the respected Encyclopedia series is the first in many years to bring together all important aspects of developmental biology in one source, from morphogenesis and organogenesis, via epigenetic regulation of gene expression to evolutionary developmental biology. The editor-in-chief has assembled an outstanding team of contributors to review these topics, creating an authoritative work for many years to come. The result is a unique, top-level reference in developmental biology for researchers, students and professionals alike.
Frontiers in Food Biotechnology
by Jayachandra S. Yaradoddi Bharati S. Meti Sulochana B. Mudgulkar Dayanand AgsarThis is a great book to explore the science underlying the Food Biotechnology, which explores and presents current biotechnological advances and approaches to improving the nutritional value of modern-foods. Novel fermentation and enzyme technological processes, protein engineering, genetic engineering, metabolic engineering, bioengineering, quorum sensing and nanobiotechnology have been incorporated to fetch into new dimensions in current food biotechnology research and this book provides a deep insight on all these aspects as a comprehensive resource for anybody interested in all the types of foods, latest processing, preservation technology and safety. Written by leading scientists in the field, the book will be a valuable resource for students and researchers in the fields of food chemistry, nutritional science, taste physiology, and neuroscience, as well as for professionals in the food industry.
Frontiers in Fusion Research
by Mitsuru KikuchiFrontiers in Fusion Research provides a systematic overview of the latest physical principles of fusion and plasma confinement. It is primarily devoted to the principle of magnetic plasma confinement, that has been systematized through 50 years of fusion research. Frontiers in Fusion Research begins with an introduction to the study of plasma, discussing the astronomical birth of hydrogen energy and the beginnings of human attempts to harness the Sun's energy for use on Earth. It moves on to chapters that cover a variety of topics such as: * charged particle motion, * plasma kinetic theory, * wave dynamics, * force equilibrium, and * plasma turbulence. The final part of the book describes the characteristics of fusion as a source of energy and examines the current status of this particular field of research. Anyone with a grasp of basic quantum and analytical mechanics, especially physicists and researchers from a range of different backgrounds, may find Frontiers in Fusion Research an interesting and informative guide to the physics of magnetic confinement.
Frontiers in Fusion Research II
by Mitsuru Kikuchi Masafumi AzumiThis book reviews recent progress in our understanding of tokamak physics related to steady state operation, and addresses the scientific feasibility of a steady state tokamak fusion power system. It covers the physical principles behind continuous tokamak operation and details the challenges remaining and new lines of research towards the realization of such a system. Following a short introduction to tokamak physics and the fundamentals of steady state operation, later chapters cover parallel and perpendicular transport in tokamaks, MHD instabilities in advanced tokamak regimes, control issues, and SOL and divertor plasmas. A final chapter reviews key enabling technologies for steady state reactors, including negative ion source and NBI systems, Gyrotron and ECRF systems, superconductor and magnet systems, and structural materials for reactors. The tokamak has demonstrated an excellent plasma confinement capability with its symmetry, but has an intrinsic drawback with its pulsed operation with inductive operation. Efforts have been made over the last 20 years to realize steady state operation, most promisingly utilizing bootstrap current. Frontiers in Fusion Research II: Introduction to Modern Tokamak Physics will be of interest to graduate students and researchers involved in all aspects of tokamak science and technology.
Frontiers in General Relativity (Lecture Notes in Physics #984)
by Dirk Puetzfeld Peter A. HoganThis book discusses some of the open questions addressed by researchers in general relativity. Photons and particles play important roles in the theoretical framework, since they are involved in analyzing and measuring gravitational fields and in constructing mathematical models of gravitational fields of various types. The authors highlight this aspect covering topics such as the construction of models of Bateman electromagnetic waves and analogous gravitational waves, the studies of gravitational radiation in presence of a cosmological constant and the gravitational compass or clock compass for providing an operational way of measuring a gravitational field. The book is meant for advanced students and young researchers in general relativity, who look for an updated text which covers in depth the calculations and, equally, takes on new challenges. The reader, along the learning path, is stimulated by provocative examples interspersed in the text that help to find novel representations of the uses of particles and photons.
Frontiers in Geotechnical Engineering (Developments in Geotechnical Engineering)
by Madhavi Latha G.This volume contains contributions by eminent researchers in the field of geotechnical engineering. The chapters of this book are based on the keynote and theme lectures delivered at the Indian Geotechnical Conference 2018, and discuss the recent issues and challenges, while providing perspective on the possible solutions and future directions. A strong emphasis is placed on proving connections between academic research and field practice, with many examples and case studies. Topics covered in this volume include contemporary infrastructural challenges, underground space utilization, sustainable construction, dealing with problematic soils and situations and geo-environmental issues including landfills. This book will be of interest to researchers, practitioners and students alike.
Frontiers in Magnetic Materials: From Principles to Material Design and Practical Applications
by Chen Wu Jiaying JinThe book aims to provide comprehensive and practical guidance on magnetism and magnetic materials. It involves four parts, focusing on fundamental magnetism, hard magnetic materials, soft magnetic materials and other functional magnetic materials. Part I highlights the ubiquity of magnetism and the close relationships between magnetic materials and our daily life. Perspectives on magnetism from Engineering and Physics are provided to introduce the two unit systems, followed by the origin and categories of magnetisms. An introduction of important parameters during magnetization and magnetic measurement techniques are then provided to lay a solid foundation for the readers for better understandings of the design and development of different magnetic materials. Important magnetic materials are then introduced in the subsequent parts, delivering an overview of design principles, production technologies, research developments and real-world applications. For instance, rare-earth-free and rare-earth-based hard magnetic materials as well as soft magnetic materials such as Fe-based alloys, composites and ferrites are discussed. Other functional magnetic materials span a wide range, involving smart materials with magneto-X effects, together with magnetic materials for applications including electromagnetic wave absorption, biomedicine and catalysis, etc. For these magnetic materials, more emphasis is placed on the latest advances and interdisciplinary perspectives.
Frontiers in Nonlinear Optics, The Sergei Akhmanov Memorial Volume: The Sergei Akhmanov Memorial Volume
by H. Walther N. Koroteev M.O. ScullyIn tribute to the memory of Sergei Akhmanov, a pioneer in the field, Frontiers in Nonlinear Optics presents an overview of quantum electronics and nonlinear optics. The contributors, world leaders in this field, provide up-to-date surveys and current trends to ensure comprehensive coverage in all aspects of nonlinear optics. This fascinating collection is necessary reading both for researchers entering the field and for established researchers in nonlinear optics.
Frontiers in Optical Methods
by Ken-Ichi Shudo Ikufumui Katayama Shin-Ya OhnoThis collection of reviews by leading Japanese researchers covers topics like ultrafast optical responses, terahertz and phonon studies, super-sensitive surface and high-pressure spectroscopy, combination of visible and x-ray photonics. Several related areas at the cutting edge of measurement technology and materials science are included. This book is partly based on well-cited review articles in the Japanese language in special volumes of the Journal of the Vacuum Society of Japan.
Frontiers in Pharmacology of Neurotransmitters
by Puneet Kumar Pran Kishore DebNumerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels. It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels. Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.
Frontiers in Protein Structure, Function, and Dynamics
by Dev Bukhsh Singh Timir TripathiThis book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
Frontiers in Psychiatry: Artificial Intelligence, Precision Medicine, and Other Paradigm Shifts (Advances in Experimental Medicine and Biology #1192)
by Yong-Ku KimThis book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.