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Frontiers in Pharmacology of Neurotransmitters
by Puneet Kumar Pran Kishore DebNumerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels. It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels. Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.
Frontiers in Protein Structure, Function, and Dynamics
by Dev Bukhsh Singh Timir TripathiThis book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
Frontiers in Psychiatry: Artificial Intelligence, Precision Medicine, and Other Paradigm Shifts (Advances in Experimental Medicine and Biology #1192)
by Yong-Ku KimThis book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.
Frontiers in Quantum Methods and Applications in Chemistry and Physics
by M.A.C. Nascimento Jean Maruani Erkki J. Brändas Gerardo Delgado-BarrioThis edited, multi-author volume contains 14 selected, peer-reviewed contributions based on the presentations given at the 18th International Workshop on Quantum Systems in Chemistry, Physics, and Biology (QSCP XVIII), held at Casa da Cultura de Paraty, Rio de Janeiro, Brazil, in December 2013. It is divided into several sections written by leaders in the respective fields of quantum methodology applied to atomic molecular and condensed matter systems, each containing the most relevant material based on related topics. Recent advances and state-of-the-art developments in the quantum theory of atomic, molecular and condensed matter systems (including bio and nano structures) are presented.
Frontiers in Soil and Environmental Microbiology
by Bibhuti Bhusan Mishra Suraja Kumar NayakSoil harbours a wide range of microorganisms with biotic potentials which can be explored for social benefits. The book Frontiers in Soil and Environmental Microbiology comprises an overview of the complex inter-relationship between beneficial soil microbes and crop plants, and highlights the potential for utilisation to enhance crop productivity, bioremediation and soil health. The book focusses on important areas of research such as biocide production, pesticide degradation and detoxification, microbial decay processes, remediation of soils contaminated with toxic metals, industrial wastes, and hydrocarbon pollutants. Features Presents the state of the art of microbial research in environmental and soil microbiology Discusses an integrated and systematic compilation of microbes in the soil environment and its role in agriculture and plant growth and productivity Elucidates microbial application in environmental remediation Explores advanced genomics topics for uncultivable microbes of soil
Frontiers in Spray Drying (Advances in Drying Science and Technology)
by Jie Xiao Meng Wai Woo Nan Fu Xiao Dong ChenThis book covers the latest developments and advances in spray drying and describes how they impact the basic aspect of designing and operating spray dryers. This generic approach allows users to understand how different basic aspects of spray drying have advanced. Users will learn how to apply these advances in their own specific spray drying applications. This book also discusses the handling and control of spray dried products. Includes the latest techniques for use in the design and operation of spray drying operations Covers the basic operations of spray drying that can be applied to different applications of spray drying Discusses the handling and control of spray dried product qualities from a general approach, allowing readers to tailor these approaches to their own specific products This book is aimed at professionals, researchers, and academics working in the fields of food, chemical, pharmaceutical, and industrial engineering.
Frontiers in Stochastic Analysis–BSDEs, SPDEs and their Applications: Edinburgh, July 2017 Selected, Revised and Extended Contributions (Springer Proceedings in Mathematics & Statistics #289)
by Samuel N. Cohen István Gyöngy Gonҫalo Dos Reis David Siska Łukasz SzpruchThis collection of selected, revised and extended contributions resulted from a Workshop on BSDEs, SPDEs and their Applications that took place in Edinburgh, Scotland, July 2017 and included the 8th World Symposium on BSDEs. The volume addresses recent advances involving backward stochastic differential equations (BSDEs) and stochastic partial differential equations (SPDEs). These equations are of fundamental importance in modelling of biological, physical and economic systems, and underpin many problems in control of random systems, mathematical finance, stochastic filtering and data assimilation. The papers in this volume seek to understand these equations, and to use them to build our understanding in other areas of mathematics.This volume will be of interest to those working at the forefront of modern probability theory, both established researchers and graduate students.
Frontiers in Water-Energy-Nexus—Nature-Based Solutions, Advanced Technologies and Best Practices for Environmental Sustainability: Proceedings of the 2nd WaterEnergyNEXUS Conference, November 2018, Salerno, Italy (Advances in Science, Technology & Innovation)
by Vincenzo Naddeo Malini Balakrishnan Kwang-Ho ChooThis volume includes selected contributions presented during the 2nd edition of the international conference on WaterEnergyNEXUS which was held in Salerno, Italy in November 2018. This conference was organized by the Sanitary Environmental Engineering Division (SEED) of the University of Salerno (Italy) in cooperation with Advanced Institute of Water Industry at Kyungpook National University (Korea) and with The Energy and Resources Institute, TERI (India). The initiative received the patronage of UNESCO – World Water Association Programme (WWAP) and of the International Water Association (IWA) and was organized with the support of Springer (MENA Publishing Program), Arab Water Council (AWC), Korean Society of Environmental Engineering (KSEE) and Italian Society of Sanitary Environmental Engineering Professors (GITISA). With the support of international experts invited as plenary and keynote speakers, the conference aimed to give a platform for Euro-Mediterranean countries to share and discuss key topics on such water-energy issues through the presentation of nature-based solutions, advanced technologies and best practices for a more sustainable environment. This volume gives a general and brief overview on current research focusing on emerging Water-Energy-Nexus issues and challenges and its potential applications to a variety of environmental problems that are impacting the Euro-Mediterranean zone and surrounding regions. A selection of novel and alternative solutions applied worldwide are included. The volume contains over about one hundred carefully refereed contributions from 44 countries worldwide selected for the conference. Topics covered include (1) Nexus framework and governance, (2) Environmental solutions for the sustainable development of the water sector, (3) future clean energy technologies and systems under water constraints, (4) environmental engineering and management, (5) Implementation and best practices Intended for researchers in environmental engineering, environmental science, chemistry, and civil engineering. This volume is also an invaluable guide for industry professionals working in both water and energy sectors.
Frontiers of Astrobiology
by Chris Impey Jonathan Lunine José FunesAstrobiology is an exciting interdisciplinary field that seeks to answer one of the most important and profound questions: are we alone? In this volume, leading international experts explore the frontiers of astrobiology, investigating the latest research questions that will fascinate a wide interdisciplinary audience at all levels. What is the earliest evidence for life on Earth? Where are the most likely sites for life in the Solar System? Could life have evolved elsewhere in the Galaxy? What are the best strategies for detecting intelligent extraterrestrial life? How many habitable or Earth-like exoplanets are there? Progress in astrobiology over the past decade has been rapid and, with evidence accumulating that Mars once hosted standing bodies of liquid water, the discovery of over 500 exoplanets and new insights into how life began on Earth, the scientific search for our origins and place in the cosmos continues.
Frontiers of Energy and Environmental Engineering
by Ran Chen Jimmy C.M. Kao Wen-Pei SungFrontiers of Energy and Environmental Engineering brings together 192 peer-reviewed papers presented at the 2012 International Conference on Frontiers of Energy and Environment Engineering, held in Hong Kong, December 11-13, 2012. The aim of the conference was to provide a platform for researchers, engineers and academics as well as industry profes
Frontiers of Engineering
by National Academy of EngineeringCe livre historique peut contenir de nombreuses coquilles et du texte manquant. Les acheteurs peuvent generalement telecharger une copie gratuite scannee du livre original (sans les coquilles) aupres de lediteur. Non reference. Non illustre. 1856 edition. Extrait: . . . separe, une quantite de tetes de betail proportionnee a letendue de lexploitation, et suivant les dispositions des regles que je vous ai ci-dessus tracees. (Art. 15. ) IV. Quelques precautions ont ete prises enfin par la loi, pour proteger les cultures et les recoltes contre les abus journaliers du parcours et de la vaine pature. 1 Dans aucun cas, et dans aucun temps, ces droits ne peuvent sexercer sur les prairies artificielles, et ne peuvent avoir lieu sur aucune terre ensemencee ou couverte de quelques productions que ce soit, quapres la recolte. (. , art. 9. ) 2 Partout ou les prairies naturelles sont sujettes au parcours ou a la vaine pature, ils nont lieu que dans le temps autorise par les lois et coutumes, et jamais tant que la premiere herbe nest pas recoltee. (Ib. , art. 10. ) 3 Enfin, dans les lieux de parcours ou de vaine pature, comme dans ceux ou ces usages ne sont pas etablis, les patres et les bergers ne peuvent mener les troupeaux daucune espece dans les champs moissonnes et ouverts, que deux jours apres la recolte entiere, sous peine dune amende de la valeur dune journee de travail: lamende est double si les bestiaux ont penetre dans un enclos rural. (Art. 22. ) Cette suspension de lintroduction du betail dans les champs cultives a surtout ete etablie dans linteret du glanage et des malheureux pour lesquels il est une precieuse ressource. V. 11 fallait enfin coordonner les regles du parcours et de la vaine pature avec. . .
Frontiers of Engineering: Reports on Leading-Edge Engineering from the 2010 Symposium
by National Academy of Engineering of the National AcademiesThis volume highlights the papers presented at the National Academy of Engineering's 2010 U.S. Frontiers of Engineering Symposium. Every year, the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and technical work. The 2010 symposium was held September 23 - 25, and hosted by IBM at the IBM Learning Center in Armonk, New York. Speakers were asked to prepare extended summaries of their presentations, which are reprinted here. The intent of this book is to convey the excitement of this unique meeting and to highlight cutting-edge developments in engineering research and technical work.
Frontiers of Engineering: Reports on Leading-Edge Engineering from the 2015 Symposium
by National Academy of EngineeringThis volume presents papers on the topics covered at the National Academy of Engineering's 2015 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2015 symposium was held September 9-11 at the Arnold and Mabel Beckman center in Irvine, California. The intent of this book is to highlight innovative developments in engineering research and technical work.
Frontiers of Engineering: Reports on Leading-edge Engineering from the 2002 NAE Symposium on Frontiers of Engineering
by National Academy of Engineering StaffThis collection includes summaries of presentations given at the NAE Symposium in September 2002. Topics include chemical and molecular engineering in the 21st century, human factors engineering, the future of nuclear energy, and engineering challenges for quantum information technology.
Frontiers of Forest Biology: Proceedings of the 1998 Joint Meeting of the North American Forest Biology Workshop and the Western
by A K Mitchell Pasi Puttonen M Stoehr Barbara J HawkinsDiscover new approaches to promote a viable forest industry while protecting non-timber values!Frontiers of Forest Biology: Proceedings of the 1998 Joint Meeting of the North American Forest Biology Workshop and the Western Forest Genetics Association gives you significant new insights on current initiatives in forest biology. Because the field is changing rapidly, you need to keep aware of current trends, as the emphasis in forest research shifts from productivity-based goals to sustainable development of forest resources. In this volume, you will find a comprehensive summary of the state of the art of forest science in North America. Whether your focus is on genetics or on the environmental aspects of forest science, plant physiology, or silviculture, you will find helpful chapters by practitioners as well as cutting-edge research by scientists. This integrated approach is unique in the field. Based on the 1998 Joint Meeting of the North American Forest Biology Workshop and the Western Forest Genetics Association, Frontiers of Forest Biology addresses changing priorities in forest resource management. This important book contains fascinating research studies, complete with tables and diagrams, on topics such as biodiversity research, the productivity of commercial species, conserving adaptive variation in forest ecosystems, and the effect of harvesting trees on nutrient leaching.The book maps the frontiers of this fast-changing science with chapters on: the social, biological, and industrial context of forest biology new directions for research into genetics, physiology, plant silviculture, and conservation the impact of genetics on sustainable forestry the effects of cold and disease on plant physiology regeneration of various species after logging new species adapted for agroforestry the impact and management of exotic weedsFrontiers of Forest Biology offers solid information on a broad spectrum of topics and suggests fresh avenues for your investigations in all aspects of forest biology.
Frontiers of Fundamental Physics FFP16: Fundamental Physics and Physics Education (Springer Proceedings in Physics #392)
by Burra G. Sidharth Marisa Michelini Ekrem Aydiner Christian CordaThis book is a collection of contributions presented at the 16th annual international symposium “Frontiers of Fundamental Physics” (FFP16), supported by Istanbul University. As a document of the latest occurrence of this very important gathering, it presents the most recent advances in fundamental physics and physics teaching. For nearly fifteen years, the FFP has attracted some of the greatest physicists in the world. The broad objective of the entire endeavor has been to enable scholars working in slightly different areas to meet on a single platform. Even with this particular year’s safety restrictions arising from Covid, we feel that the general mission has been carried out as fully as in any year. The book features addresses given by a host of expert contributors, all of which are organized according to seven individual themes. The areas covered include Astronomy and Astrophysics, Particle Physics, Theoretical Physics, Gravitation and Cosmology, Computational Physics, Condensed Matter Physics, Complex Systems and related areas. This book should prove to be a veritable bounty for anyone with an interest in the continued evolution of our understanding of the physical world.
Frontiers of Fundamental Physics and Physics Education Research
by Burra G. Sidharth Marisa Michelini Lorenzo SantiIn a knowledge-based society, research into fundamental physics plays a vital role not only in the enhancement of human knowledge but also in the development of new technology that affects everyday life. The international symposium series Frontiers of Fundamental Physics (FFP) regularly brings together eminent scholars and researchers working in various areas in physics to exchange expertise, ideas, results, and new research perspectives. The twelfth such symposium, FFP12, took place at the University of Udine, Italy, and covered diverse fields of research: astrophysics, high energy physics and particle physics, theoretical physics, gravitation and cosmology, condensed matter physics, statistical physics, computational physics, and mathematical physics. Importantly, it also devoted a great deal of attention to physics education research, teacher training in modern physics, and popularization of physics. The high scientific level of FFP12 was guaranteed by the careful selection made by scientific coordinators from among 250 submissions from 28 countries across the world. During the three days of the conference, nine general talks were delivered in plenary sessions, 29 invited talks were given in specific topic areas, and 59 oral presentations were made. This book presents a selection of the best contributions at FFP12 with the aim of acquainting readers with the most important recent advances in fundamental physics and in physics education and teacher development.
Frontiers of Green Catalytic Selective Oxidations (Green Chemistry and Sustainable Technology)
by Konstantin P. BryliakovThe demand for novel efficient and environmentally sustainable chemo, regio- and stereoselective catalyst systems for the oxidation of organic substrates is continuously growing in line with toughening economic and environmental constraints. This book addresses these issues; it consists of eleven chapters written by world-recognized experts in green and sustainable oxidation catalysis. The most urgent and challenging topics, in the judgment of the editor, such as green asymmetric epoxidations, sulfoxidatiuons, C–H oxidations; oxidation catalysis by polyoxometalates and oxidations in non-conventional solvents, etc. have been critically reviewed in this book. Both fundamental aspects, such as catalysts design, catalytic properties, nature of catalytically active sites and reaction mechanisms, and practical outlook of the oxidations have been addressed by the authors. The book appeals to a broad readership, particularly graduate students, employees of universities and research organizations, and industrial researchers, particularly those working in the areas of homogeneous oxidation catalysis, asymmetric synthesis, organocatalysis, sustainable catalytic processes and green chemistry, mechanisms of catalytic reactions, synthesis of bioactive compounds, biomimetic chemistry, etc.Konstantin Bryliakov is Leading Researcher at the Boreskov Institute of Catalysis. In 2016, he was elected Honorary Professor of the Russian Academy of Sciences.
Frontiers of Land and Water Governance in Urban Areas (Routledge Special Issues on Water Policy and Governance)
by Thomas Hartmann and Tejo SpitA society that intensifies and expands the use of land and water in urban areas needs to search for solutions to manage the frontiers between these two essential elements for urban living. Sustainable governance of land and water is one of the major challenges of our times. Managing retention areas for floods and droughts, designing resilient urban waterfronts, implementing floating homes, or managing wastewater in shrinking cities are just a few examples where spatial planning steps into the governance arena of water management and vice versa. However, water management and spatial planning pursue different modes of governance, and therefore the frontiers between the two disciplines require developing approaches for setting up governance schemes for sustainable cities of the future. What are the particularities of the governance of land and water? What is the role of regional and local spatial planning? What institutional barriers may arise? This book focuses on questions such as these, and covers groundwater governance, water supply and wastewater treatment, urban riverscapes, urban flooding, flood risk management, and concepts of resilience. The project resulted from a Summer School by the German Academy for Spatial Research and Planning (ARL) organized by the editors at Utrecht University in 2013.This book was published as a special issue of Water International.
Frontiers of Nanobiotechnology: Microfluidic Devices and BioMEMS for the Future (Series in BioEngineering)
by Seyed Morteza Naghib Yasaman RezaeianThis book provides a comprehensive overview of microfluidic-assisted devices and bioMEMS, covering their fundamental principles, manufacturing processes, and biomedical applications. It explores the design, fabrication, and integration of microfluidic devices and MEMS, emphasizing their role in microscale physics and biomedical engineering. Key topics include micropumps, biosensors, and organ-on-a-chip systems, with applications in drug discovery, disease diagnosis, and tissue engineering. The book also discusses recent advances in the field, particularly the integration of biosensors with microfluidic systems, highlighting their growing impact on biomedical research and healthcare innovations.
Frontiers of Performability Engineering: In Honor of Prof. K.B. Misra (Risk, Reliability and Safety Engineering)
by Durga Rao KarankiThis book presents recent advances in performability analysis methods and their applications in different fields. It covers various aspects of performability such as quality, reliability, maintainability, availability, safety, security, and sustainability that are essential in complex engineering systems such as electrical grids, chemical plants, naval defense systems, structures, nuclear reactors, railways, etc. This book is a collection of research works contributed by the former students of Professor KB Mishra who is a renowned researcher in reliability engineering. This book is useful for the researchers and professionals working in the area of performability engineering.
Frontiers of Quantum Chemistry
by Yukihiro Ozaki Bernard Kirtman Marek J. Wójcik Hiroshi NakatsujiThe purpose of this book is to convey to the worldwide scientific community the rapid and enthusiastic progress of state-of-the-art quantum chemistry. Quantum chemistry continues to grow with remarkable success particularly due to rapid progress in supercomputers. The usefulness of quantum chemistry is almost limitless. Its application covers not only physical chemistry but also organic and inorganic chemistry, physics, and life sciences. This book deals with all of these topics. Frontiers of Quantum Chemistry is closely related to the symposium of the same name held at Kwansei Gakuin University at Nishinomiya, Japan, in November 2015. The book's contributors, however, include not only invited speakers at the symposium but also many other distinguished scientists from wide areas of quantum chemistry around the world.
Frontiers of Science: Imperialism and Natural Knowledge in the Gulf South Borderlands, 1500-1850 (Published by the Omohundro Institute of Early American History and Culture and the University of North Carolina Press)
by Cameron B. StrangCameron Strang takes American scientific thought and discoveries away from the learned societies, museums, and teaching halls of the Northeast and puts the production of knowledge about the natural world in the context of competing empires and an expanding republic in the Gulf South. People often dismissed by starched northeasterners as nonintellectuals--Indian sages, African slaves, Spanish officials, Irishmen on the make, clearers of land and drivers of men--were also scientific observers, gatherers, organizers, and reporters. Skulls and stems, birds and bugs, rocks and maps, tall tales and fertile hypotheses came from them. They collected, described, and sent the objects that scientists gazed on and interpreted in polite Philadelphia. They made knowledge.Frontiers of Science offers a new framework for approaching American intellectual history, one that transcends political and cultural boundaries and reveals persistence across the colonial and national eras. The pursuit of knowledge in the United States did not cohere around democratic politics or the influence of liberty. It was, as in other empires, divided by multiple loyalties and identities, organized through contested hierarchies of ethnicity and place, and reliant on violence. By discovering the lost intellectual history of one region, Strang shows us how to recover a continent for science.
Frontiers of Shock Wave Research
by Ozer Igra Kazuyoshi TakayamaThe book contains 12 chapters written by well-known shock wave researchers from seven different countries. Each researcher provides a brief description of his main research interests and results, thereby providing the readers with an excellent view of shock wave research conducted in the past fifty years. It also provides hints as to what still needs further investigation. It will be an excellent guide for young researchers entering the field of shock wave phenomena. Among the described investigations are the following topics: Blast wave interaction with a body when the body is in the area of interference of two blast waves moving in different directions; equation of state for water based on the shock Hugoniot data; Mach waves occurring over a backward facing edge in supersonic flow; shock waves in dusty gas; shock wave interaction with various bodies; three shock interactions.
Frontiers of Space Risk: Natural Cosmic Hazards & Societal Challenges
by Richard J. Wilman and Christopher J. NewmanCHOICE Recommended Title, March 2019 This book brings together diverse new perspectives on current and emerging themes in space risk, covering both the threats to Earth-based activities arising from space events (natural and man-made), and those inherent in space activity itself. Drawing on the latest research, the opening chapters explore the dangers from asteroids and comets; the impact of space weather on critical technological infrastructure on the ground and in space; and the more uncertain threats posed by rare hazards further afield in the Milky Way. Contributors from a wide range of disciplines explore the nature of these risks and the appropriate engineering, financial, legal, and policy solutions to mitigate them. The coverage also includes an overview of the space insurance market; engineering and policy perspectives on space debris and the sustainability of the space environment. The discussion then examines the emerging threats from terrorist activity in space, a recognition that space is a domain of war, and the challenges to international cooperation in space governance from the nascent asteroid mining industry. Features: Discusses developments and risks relevant to the public and private sectors as access to the space environment expands Offers an interdisciplinary approach blending science, technology, and policy Presents a high-level international focus, with contributions from academics, policy makers, and commercial space consultants