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Gold Nanoparticles in Biomedical Applications
by Lev Dykman Nikolai KhlebtsovThis book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.
Gold Nanostars
by Giuseppe Chirico Mykola Borzenkov Piersandro PallaviciniThis Brief focuses on the synthesis, functionalization techniques, optical properties and biomedical application of gold nanostars (GNS). Various facilities of gold nanostars synthesis as well as functionalization of GNS with PEG, organic dyes, bioactive compounds are discussed. The authors discuss physical origin of the Localized Surface Plasmon Resonances and the way the nano-environment affects them. The implication of the LSPR of gold nanostars surface enhanced Raman scattering is also discussed. The emphasis has been done on the application of GNS for current and emerge needs of medicine, biology and pharmacy. Moreover, properties of gold nanostars as contrast agents for in vivo imaging and interaction of GNS with cells are also discussed in this Brief.
Gold Region:Sci Tra 1791-1877
by Thomas BainesThis book contains a preface, a memoir and an obituary notice, which together provide a good account of Thomas Baines' life. It includes advertisements aimed especially at would-be emigrants to South Africa. The book is an important document of colonial history and South African history.
Gold Rush in the Jungle: The Race to Discover and Defend the Rarest Animals of Vietnam's "Lost World"
by Dan DrolletteAn engrossing, adventure-filled account of the rush to discover and save Vietnam's most extraordinary animals Deep in the jungle where the borders of Vietnam meet those of Laos and Cambodia is a region known as "the lost world." Large mammals never seen before by Western science have popped up frequently in these mountains in the last decade, including a half-goat/half-ox, a deer that barks, and a close relative of the nearly extinct Javan rhino. In an age when scientists are excited by discovering a new kind of tube worm, the thought of finding and naming a new large terrestrial mammal is astonishing, and wildlife biologists from all over the world are flocking to this dangerous region. The result is a race between preservation and destruction. Containing research gathered from famous biologists, conservationists, indigenous peoples, former POWs, ex-Viet Cong, and the first U.S. ambassador to Vietnam since the war's end, Gold Rush in the Jungle goes deep into the valleys, hills, and hollows of Vietnam to explore the research, the international trade in endangered species, the lingering effects of Agent Orange, and the effort of a handful of biologists to save the world's rarest animals.
Gold and Silver Staining: Techniques in Molecular Morphology (Advances in Pathology, Microscopy, & Molecular Morphology)
by Gerhard W. Hacker Jiang GuImmunogold silver staining is one of the most sensitive techniques available for visualizing the location of antibodies and nucleotide probes that have been bounded to specific antigens or to nucleotide sequences. As gold and silver staining continues to advance research in molecular morphology, this book presents the information you need to know a
Gold and its Complexes in Anticancer Chemotherapy
by Mohmmad Younus Wani Manzoor Ahmad MalikThis book presents an overview of cancer and the genesis, and development of different treatment strategies and modalities against cancer. The emergence of gold and its complexes as promising anticancer chemotherapeutic agents have the potential to substitute or replace the platinum based chemotherapeutic agents. Gold complexes have demonstrated considerable anti-proliferative properties, chiefly attributed to their anti-mitochondrial effects, they make gold complexes excellent candidates as anti-cancer agents compared to their platinum-based counterparts. This book provides a critical review of recent advances made in the development of gold complexes as anti-cancer agents. In this context, it examines a number of different ligand architectures, provides comprehensive information on gold complexes’ mechanism of action and toxicity issues and, in closing, outlines future research directions.
Gold-Catalyzed Cycloisomerization Reactions Through Activation of Alkynes
by Antoine SimonneauAntoine Simonneau's thesis highlights the development of new cycloisomerization reactions through the activation of alkynes with gold complexes. First Simonneau describes 1,6-enynes and their direct conversion into allenes through 1,5-hydride or ester migration processes. The author and his team used appropriate propargylic functional groups to achieve this conversion. This study shows that O-tethered 1,6-enynes carrying a strained cycloalkane at the propargylic position could undergo a cyclopropanation/ring expansion cascade reaction. The author employed this rearrangement as the starting point in the design of a new macro cycle synthesis. The next part of the thesis focuses on the cycloisomerization of diynes involving as the first step of the process the rearrangement of one alkyne partner into an allene thanks to a gold-catalyzed 1,3-shift of a propargylic ester. The thesis discloses a new cycloisomerization pattern featuring a 1,5-carbonyl transfer, giving rise to unprecedented cross-conjugated diketones. In the final part of the research, Simmoneau investigates the gold-catalyzed cycloisomerization mechanism of 1,6-enynes and questions the intermediacy of gold acetylides. By the means of NMR and mass spectrometry analysis, theoretical treatment and solution experiments, it was possible to rule out the involvement of these species in the catalytic cycle. This thesis has led to a number of publications in high-impact journals.
Gold: Israel Regardie's Lost Book of Alchemy
by Israel Regardie Chic Cicero Sandra Tabatha CiceroIn this newly discovered text, famed occultist Israel Regardie sheds light on the psychological and spiritual meaning behind the symbols and metaphors of alchemy. Locked away for years before it was made available, and now fully annotated by Chic and Sandra Tabatha Cicero, Gold is the first new book by Regardie published in decades.Analyzing important seventeenth-century alchemical treatises, such as "The True Book of the Learned Synesius," Regardie uses the language of Jungian psychology, magnetism, and hypnosis while citing his own unique experiences as a therapist and healer. Learn about spiritual alchemy and the connection between ancient magic and modern-day psychology. Explore the similarities between alchemical theory, Taoist philosophy, yoga, Zen Buddhism, and experiments with the human aura. With illustrations and appendices, including Regardie's original text "The Art of True Healing," Gold is a definitive work by a true master.
Gold: Science and Applications
by Christopher Corti Richard HollidayGold is used in a wide range of industrial and medical applications and accounts for over 10 percent of the annual demand for metal, worth billions of dollars annually. While much has been written about the mystique and trade of gold, very little has been written about the science and technology in which it is involved. Edited by two respected auth
Golden Gate Cloning: Methods and Protocols (Methods in Molecular Biology #2850)
by Daniel SchindlerThis volume provides an overview of the latest protocols that cover the full range of in silico, in vitro, and in vivo approaches to help researchers plan, design, and perform Golden Gate cloning experiments. The chapters in this book cover topics such as Golden Gate cloning of standardized parts; modular DNA construct design for high-throughput Golden Gate Assembly; Golden Gate cloning of Synthetic CRISPR RNA spacer sequences; Golden Gate cloning in Actinobacteria; and YeastFab cloning of toxic genes and protein expression optimization in yeast. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Golden Gate Cloning: Methods and Protocols is a valuable resource for all researchers interested in learning more about this important and developing field. Chapter 3 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Golden Lads: Sir Francis Bacon, Anthony Bacon, and Their Friends
by Daphne Du Maurier"Daphne du Maurier has no equal." --Sunday TelegraphPrior to the publication of Golden Lads, Anthony Bacon was viewed as a footnote in the history of his younger brother, Francis. A fascinating historical figure in his own right, Anthony Bacon was a contemporary of the brilliant band of gallants who gathered around the court of Elizabeth I, was closely connected to the Earl of Essex, and worked in France as a spy for Sir Francis Walsingham. While living in France he became acquainted with Henri IV and the essayist Michel de Montaigne, and it was there that Daphne du Maurier discovered a secret that, if disclosed during Bacon's lifetime, could have put an end to his political career. Du Maurier did much to uncover the truth behind matters that had long puzzled Elizabethan historians, while telling a strange and fascinating tale.
Golden Retrievers and Other Sporting Dogs (World Book's Animals of the World)
by Robert Blackburn KnightIntroduces the Golden Retriever dog breed and talks about other sporting dogs, in a question and answer format.
Golden Shadows, Flying Hooves: With A New Afterword
by George B. SchallerGeorge Schaller here shares with his reader the fascinating personal story behind his scientific discoveries that have so notably advanced our knowledge of the great African predators. In his new books, he allows us to participate moment by moment in his work and his experience on the Tanzanian plains as for three years he made his extraordinary of the habits, the hunting methods, the social systems, and the behavior—the lives from birth to death—of the lion, the wild dog, the cheetah, the leopard, and the hyena. We follow him afoot and in a Land-Rover, through the thickets, plains, and wooded grasslands of this wild, harsh landscape as he tranquilizes and then tags the great predators, as he gets to know their individual characteristics, as he investigates the vast array of species they depend upon for survival. We feel Schaller’s exaltation in the pure sensual motions of a lion stalking its prey, watch with him as a small furry mouse defends itself valiantly against a pack of wild dogs, as an Egyptian vulture breaks an ostrich eggs with a stone . . . We come to know the various postures of the animals in the hunt, what their territorial range is, how they behave with one another, how they raise their young . . . We are there as Schaller hangs a tiny radio transmitter around the neck of an old lion—the beeps will enable him to track the animal by night as well as day. We observe the businesslike gatherings of wild dogs, the blinding speed and elegant graces of a coursing cheetah, the soft-footed stalk of the hunting leopard, the tension that ripples though a herd id gazelle when they sense an approaching predator. We go back in times, through two million years, while Schaller and his colleagues attempt to simulate the hunting behavior of that pre-human, the hominid Australopithecus, scrabbling and scavenging for food, developing, in the process of their experiment, an incredible sensitivity to the sounds of zebra, giraffe, hyena, and the low, purposeful flight of a vulture—any sign of a possible meal, shelter, enemy. And, throughout, we feel Schaller’s commitment, his strong emotional kinship with the animals he studies and with the wild landscape where he and his family created a full life for themselves far from the accouterments of modern civilizations. With the gift of expressive narrative that distinguished his famous international bestseller, The Year of the Gorilla, Schaller makes us know close-up not only the teeming life of the plains and the great human adventure he lived but also the inspired improvisation, the tirelessness, the flights of imaginations that, as much as meticulous fact-finding, are an organic part of the original scientific investigation.
Golden Years of Australian Radio Astronomy: An Illustrated History (Historical & Cultural Astronomy)
by Wayne Orchiston Peter Robertson Woodruff T. Sullivan IIIThe evolution of Australian radio astronomy from 1945 to 1960 has been studied in detail by numerous historians of science in recent years. This Open Access book is the first to present an overview of this remarkable chapter in Australian science. The book begins in the post-war period, as the Radiophysics Laboratory in Sydney switched from secret wartime research on radar to peacetime applications of this new technology. Next follows the detection of radio waves from space and the ensuing transformation of this fledgling science into the dominant research program at the Radiophysics Lab. Drawing from this history, the book shows how by 1960 the Radiophysics Lab had become the largest and most successful radio astronomy group in the world. The final chapter presents an overview of Australian radio astronomy from 1960 to the present day, as Australia prepares to co-host the multi-national, multi-billion-dollar Square Kilometre Array.Nearly 300 high-quality images complement the text, drawn from a wide range of sources including the extensive collection held by the CSIRO Radio Astronomy Image Archive. The book will be an essential reference for readers interested in the scientific and cultural development of radio astronomy.This book is published open access under a CC BY 4.0 license.
Golden-winged Warbler Ecology, Conservation, and Habitat Management (Studies in Avian Biology)
by Henry M. Streby, David E. Andersen and David A. BuehlerGolden-winged Warblers (Vermivora chrysoptera) are migratory songbirds that breed in temperate North America, primarily in the Great Lakes region with remnant populations throughout the Appalachian Mountains, and winter in Central and northern South America. Their breeding range has contracted dramatically in the Appalachian Mountains and many populations have dramatically declined, likely due to habitat loss, competition and interbreeding with Blue-winged Warblers (Vermivora pinus), andglobal climate change.. As a result of population declines in much of the eastern portion of their breeding range, Golden-winged Warblers are listed as endangered or threatened in 10 U.S. states and in Canada and have been petitioned for protection under the U.S. Endangered Species Act. Published in collaboration with and on behalf of The American Ornithological Society, this volume in the highly-regarded Studies in Avian Biology series compiles extensive, current research on Golden-winged Warblers and summarizes what is known and identifies many remaining unknowns, providing a wealth of peer-reviewed science on which future research and listing decisions can be based.
Goldfish Development and Evolution
by Kinya G. OtaThis book explains how the beautiful goldfish body develops from a single fertilized egg and how this developmental process was changed during the process of domestication. The contents can be categorized as follows: i) numerous high-quality live photo images of embryonic and larval stage goldfish, ii) detailed descriptions of skeletogenesis with fluorescent microscopic and histological images, iii) the most advanced interpretation of the relationship between artificial selection and developmental processes, iv) future perspectives of the application of the genome editing techniques for the ornamental goldfish breeding, and v) methodological descriptions for goldfish developmental biology. Goldfish is a popular ornamental domesticated fish species, and its highly diverged morphological features and color variations attract fanciers. The goldfish has been spread all over the world by breeders, and this fish has also been employed as an experimental organism by researchers in the field of life science. However, so far, no available scientific books provide a detailed description of the embryogenesis and morphogenesis of this animal. Compared with the number of published fancier books, the number of books on goldfish biology is very few. This publication will be useful not only for the research community particularly in the fields of developmental biology, evolutionary biology, zoology, aquaculture, fishery science, and related areas but also for enthusiastic goldfish fanciers and breeders.
Goldfish and Other Carp (World Book's Animals of the World)
by Al SmuskiewiczIntroduces the common goldfish, offers a history, discusses related species of fish, and explains how to care for a goldfish.
Goldie Blox Rules the School! (GoldieBlox)
by Stacy Mcanulty Lissy MarlinAn original chapter-book series featuring the characters from GoldieBlox!This all-new chapter-book series based on the successful toy line focuses on Goldie Blox’s mission to encourage girls to roll up their sleeves and get building! When Goldie Blox accidentally blows off the roof of her school, she and her friends Val, Ruby, and Li have to work together and use their creative know-how to rebuild the school. This 128-page early chapter book is a nonstop laugh-out-loud adventure and perfect for future engineers ages 6 to 9.From the Trade Paperback edition.
Goldie Blox and the Best Friend Fail! (GoldieBlox)
by Random House Stacy McAnultyCalling all Maker-kids! This STEM-based chapter book series stars engineering whiz Goldie Blox and her friends, the Gearheads!When Goldie Blox accidentally lets down her best friend, Ruby, she's determined to make it up to her by throwing her BFF the best birthday celebration ever. But will Goldie be able to pull off her wildly complicated party--or will it all end in disaster? This 128-page early chapter book is a nonstop laugh-out-loud adventure perfect for future engineers.
Goldie Blox and the Best! Pet! Ever! (GoldieBlox)
by Stacy Mcanulty Alan BatsonIn this exciting chapter book, Goldie Blox enters a pet talent show contest with the best dog ever—Nacho! When Goldie Blox enters her beloved dog Nacho in a pet talent show contest, she’s pretty sure he could win. But Nacho isn’t perfect. He doesn’t sit or shake. Instead, he farts and chases his tail. And the competition heats up when Goldie’s rival Zeek brags that he can beat Nacho with an expensive robot dog that obeys every command. Zeek thinks he can buy his way to the top, but Goldie is determined to prove him wrong. Goldie Blox’s mission is to encourage girls to roll up their sleeves and get building! This 128-page early chapter book is a nonstop laugh-out-loud adventure and perfect for future engineers ages 6 to 9.
Goldie Blox and the Haunted Hacks! (A Stepping Stone Book(TM))
by Random House Stacy McAnultyA spooky original chapter book featuring the characters from GoldieBlox!The Problem: Of course Goldie Blox doesn't believe in ghosts. But in order to save the cool old Bloxtown Inn, she will have to prove that it's haunted.The Mission: Invent glow-in-the-dark goo and pulley-operated ghosts. Use them to haunt the inn. And--yikes!--be sure not to run into an actual ghost!This chapter-book series based on the successful toy line focuses on Goldie Blox's mission to encourage girls to roll up their sleeves and get building! This 128-page early chapter book is a nonstop laugh-out-loud adventure and perfect for future engineers ages 6 to 9.The Summer 2018 GoldieBlox list includes one chapter book.
Goldie Blox and the Three Dares (GoldieBlox)
by Stacy Mcanulty Alan Batson Grace MillsAn original chapter-book series featuring the characters from GoldieBlox!This all-new chapter-book series based on the successful toy line focuses on Goldie Blox’s mission to encourage girls to roll up their sleeves and get building! When Goldie finds her beloved Gran’s book of 100 dares, she is determined to complete the last three challenges—before Gran’s 77th birthday. With the clock ticking, Goldie and her friends, the Gearheads, must use all their smarts and creativity to finish the dares and make Gran proud. This 128-page early chapter book is perfect for future engineers ages 6 to 9.From the Trade Paperback edition.
Golf Science: Optimum Performance from Tee to Green
by Mark F. SmithGolf is perhaps the most complicated simple game ever invented. Golfing greats like Jack Nicklaus and Tiger Woods make the sport look easy, but anyone who has ever picked up a club knows how truly frustrating golf can be. The success of each shot depends on a diverse range of factors, from the club you choose and the speed with which you swing it, to your mood, the weather, and even the type and cut of the grass. Science plays a crucial role in most, if not all, of these factors, and in Golf Science, sports science expert Mark F. Smith investigates the cutting-edge scientific wonders that take the ball from tee to hole. Each chapter explores a different facet of the game--mind and body, the swing, the equipment, the environment, coaching with technology, the practice process, and the score--and is organized around a series of questions. What happens in the brain during the preshot routine? Does head movement hinder swing performance? Will I hit the ball farther with a longer driver? Why do I lose distance into the wind? What can I learn from watching my ball in flight? How should practice be structured? What are the key stats in golf that I need to know? Each question is examined with the aid of explanatory diagrams and illustrations, and the book can be used to search for particular topics, or read straight through for a comprehensive overview of how golfer and equipment work together. A must-have for anyone who delights in the spirit of the game, Golf Science will be enjoyed not only by professionals and coaches but also by spectators of the PGA Tour and anyone who enjoys a round of eighteen holes on the weekend.
Golgi: Methods and Protocols (Methods in Molecular Biology #2557)
by Yanzhuang Wang Vladimir V Lupashin Todd R. GrahamThis volume provides readers with a collection of new and classical methods, techniques, and applications used to address enduring questions about the structure and functions of the Golgi complex. The chapters in this volume cover diverse topics ranging from model systems; live and fixed cell imaging techniques; in vitro biochemical reconstitution systems; and specific methods developed to study Golgi formation, maintenance, and functions under physiological and pathological conditions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Golgi: Methods and Protocols is a valuable tool for researchers in the field who wish to explore new areas of Golgi biology and for new investigators interested in exploring Golgi structure and function.
Gone Dark
by Amanda PanitchDry meets Hatchet in this thrilling tale of survival following a teen girl who must lead her friends across the country to the safety of her estranged father&’s survivalist compound after a mass power failure leaves the country in chaos.When seventeen-year-old Zara escaped her father&’s backwoods survivalist compound five years ago, she traded crossbows and skinning hides for electricity and video games…and tried to forget the tragedy that drove her away. Until a malware attack on the United States electrical grids cuts off the entire country&’s power. In the wake of the disaster and the chaos that ensues, Zara is forced to call upon skills she thought she&’d never use again—and her best bet to survive is to go back to the home she left behind. Drawing upon a resilience she didn&’t know she had, Zara leads a growing group of friends on an epic journey across a crumbling country back to her father&’s compound, where their only hope for salvation lies. But with every step she takes, Zara wonders if she truly has what it takes to face her father and the secrets of her past, or if she&’d be better off hiding in the dark.