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Aimed at advanced undergraduate and graduate students, this book provides a clear unified view of continuum mechanics that will be a welcome addition to the literature. Samuel Paolucci provides a well-grounded mathematical structure and also gives the reader a glimpse of how this material can be extended in a variety of directions, furnishing young researchers with the necessary tools to venture into brand new territory. Particular emphasis is given to the roles that thermodynamics and symmetries play in the development of constitutive equations for different materials. Continuum Mechanics and Thermodynamics of Matter is ideal for a one-semester course in continuum mechanics, with 250 end-of-chapter exercises designed to test and develop the reader's understanding of the concepts covered. Six appendices enhance the material further, including a comprehensive discussion of the kinematics, dynamics and balance laws applicable in Riemann spaces.
Continuum mechanics underlies many geological and geophysical phenomena, from earthquakes and faults to the fluid dynamics of the Earth. This interdisciplinary book provides geoscientists, physicists and applied mathematicians with a class-tested, accessible overview of continuum mechanics. Starting from thermodynamic principles and geometrical insights, the book surveys solid, fluid and gas dynamics. In later review chapters, it explores new aspects of the field emerging from nonlinearity and dynamical complexity and provides a brief introduction to computational modeling. Simple, yet rigorous, derivations are used to review the essential mathematics. The author emphasizes the full three-dimensional geometries of real-world examples, enabling students to apply this in deconstructing solid earth and planet-related problems. Problem sets and worked examples are provided, making this a practical resource for graduate students in geophysics, planetary physics and geology and a beneficial tool for professional scientists seeking a better understanding of the mathematics and physics within Earth sciences.
Continuum Mechanics of Anisotropic Materials(CMAM) presents an entirely new and unique development of material anisotropy in the context of an appropriate selection and organization of continuum mechanics topics. These features will distinguish this continuum mechanics book from other books on this subject. Textbooks on continuum mechanics are widely employed in engineering education, however, none of them deal specifically with anisotropy in materials. For the audience of Biomedical, Chemical and Civil Engineering students, these materials will be dealt with more frequently and greater accuracy in their analysis will be desired. Continuum Mechanics of Anisotropic Materials' author has been a leader in the field of developing new approaches for the understanding of anisotropic materials.
Sound knowledge of the latest research results in the thermodynamics and design of thermoelectric devices, providing a solid foundation for thermoelectric element and module design in the technical development process and thus serving as an indispensable tool for any application development. The text is aimed mainly at the project developer in the field of thermoelectric technology, both in academia and industry, as well as at graduate and advanced undergraduate students. Some core sections address the specialist in the field of thermoelectric energy conversion, providing detailed discussion of key points with regard to optimization. The international team of authors with experience in thermoelectrics research represents such institutes as EnsiCaen Université de Paris, JPL, CalTech, and the German Aerospace Center.
The leaps of knowledge in nineteenth-century science shook the foundations of religious and humanistic values throughout much of the world. The Darwinian Revolution and similar developments presented enormous philosophical challenges to Canadian scientists, philosophers, and men of letters. Their responses, many and varied, form a central theme in this collection of essays by one of Canada's leading intellectual historians.McKillop explores the thought of a number of English-Canadian thinkers from the 1860s to the 1920s, decades that saw Canada's entry into the modern age. We meet Daniel Wilson, an educator and ethnologist for whom the pursuit of science was a form of poetic engagement, requiring the poet's sensibilities; John Watson, one of the world's leading exponents of objective idealism, whose philosophical premises helped to undermine the very religious tradition he sought to bolster; and William Dawson LeSueur, an apostle of Positivism, whose spirited defence of critical inquiry and evolutionary social ethics led him towards an entirely contradictory position.In addition to profiles of individuals, McKillop considers the ways in which their ideas operated in the context of Canadian institutions including the universities and the press. From these prospectives emerges a detailed analysis of the life of the mind of English Canada in an age of questioning, of doubt, and of struggle to reorient the intellectual and philosophical positions of a quickly changing society.
The last 10 years have seen a seismic shift in therapeutic product development and testing. In both the pharmaceutical (both small and large molecule) and medical device sectors, the vast majority of testing and evaluation of products is not performed within innovator companies, but rather has been outsourced to a growing universe of commercial organizations. The authors both have more than 30 years experience in this field, and both have worked within innovator companies, for CROs, and as consultants in the field. Contract Research and Development Organizations: Their Role in Global Product Development has been crafted by these authors to provide a how to guide for all aspects of working with CROs in selecting, working with and ensuring the best possible desirable outcome of having the R&D function, or substantial parts of it, outsourced. It uses as the exemplary case nonclinical safety assessment, biocompatibility and efficacy testing which are to be performed to select the best possible candidate compound, device or formulation and then moving the resulting regulated therapeutic medical product into and through the development process and to marketing approval. But also covered are the contract synthesis of drug substances and corresponding manufacture of biologics and manufacture of products, formulation development, clinical evaluation, regulatory and document preparation support, and use of consultants. Included in the volume are an exhaustive listing of those CROs in the (drug and device) safety evaluation sector and their contact information and capabilities, and extensive similar listing for the other types of contract service providers. Also included are guidances on how to monitor ongoing work at contract facilities and audit check lists for GLP, GMP and GCP facilities. These listings are international in scope, and a specific chapter addresses working with some of the newer international CROs.
For fans of Uglies comes a spiraling, intense sci fi thriller."Control blew me away. The twists and turns and suspense made for a thrilling ride. Zel is as authentic a character as I've read in a very long time. Highly recommended" - James Dashner, New York Times bestselling author of The Maze RunnerSet in 2150 -- in a world of automatic cars, nightclubs with auditory ecstasy drugs, and guys with four arms -- this is about the human genetic "mistakes" that society wants to forget, and the way that outcasts can turn out to be heroes.When their overprotective father is killed in a terrible accident, Zel and her younger sister, Dylia, are lost in grief. But it's not until strangers appear, using bizarre sensory weapons, that the life they had is truly eviscerated. Zel ends up in a safe house for teens that aren't like any she's ever seen -- teens who, by law, shouldn't even exist. One of them -- an angry tattooed boy haunted by tragedy -- can help Zel reunite with her sister.But only if she is willing to lose him.
For fans of Uglies comes a spiraling, intense sci fi thriller. "Control blew me away. The twists and turns and suspense made for a thrilling ride. Zel is as authentic a character as I've read in a very long time. Highly recommended" - James Dashner, New York Times bestselling author of The Maze Runner Set in 2150 -- in a world of automatic cars, nightclubs with auditory ecstasy drugs, and guys with four arms -- this is about the human genetic "mistakes" that society wants to forget, and the way that outcasts can turn out to be heroes. When their overprotective father is killed in a terrible accident, Zel and her younger sister, Dylia, are lost in grief. But it's not until strangers appear, using bizarre sensory weapons, that the life they had is truly eviscerated. Zel ends up in a safe house for teens that aren't like any she's ever seen -- teens who, by law, shouldn't even exist. One of them -- an angry tattooed boy haunted by tragedy -- can help Zel reunite with her sister. But only if she is willing to lose him.
The Chemical Batch Reactor is aimed at tackling the above problems from a blending of academic and industrial perspectives. Advanced solutions (i.e., those based on recent research results) to the four fundamental problems of modeling, identification, control and fault diagnosis for batch processes are developed in detail in four distinct chapters. In each chapter, a general overview of foundational concepts is also given, together with a review of recent and classical literature on the various subjects. To provide a unitary treatment of the different topics and give a firm link to the underlying practical applications, a single case study is developed as the book progresses; a batch process of industrial interest, i.e., the phenol-formaldehyde reaction for the production of phenolic resins, is adopted to test the various techniques developed. In this way, a roadmap of the solutions to fundamental problems, ranging from the early stages of the production process to the complete design of control and diagnosis systems, is provided for both industrial practitioners and academic researchers.
Gives a real world explanation of how to analyze and troubleshoot a process control system in a batch process plant* Explains how to analyze the requirements for controlling a batch process, develop the control logic to meet these requirements, and troubleshoot the process controls in batch processes* Presents three categories of batch processes (cyclical batch, multigrade facilities, and flexible batch) and examines the differences in the control requirements in each* Examines various concepts of a product recipe and what its nature must be in a flexible batch facility* Approaches the subject from the process perspective, with emphasis on the advantages of using structured logic in the automation of all but the simplest batch processes.* Discusses the flow of information starting at the plant floor and continuing through various levels of the control logic up to the corporate IT level
The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined. Thus, this is a hugely important work that describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors such as quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.
Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineeringby Laurent Simon
Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problemsThe control of biological and drug delivery systems is critical to the health of millions of people worldwide. As a result, researchers in systems biology and drug delivery rely on process dynamics and control theory to build our knowledge of cell behavior and to develop more effective therapeutics, controlled release devices, and drug administration protocols to manage disease.Written by a leading expert and educator in the field, this text helps readers develop a deep understanding of process dynamics and control theory in order to analyze and solve a broad range of problems in bioprocess and drug delivery systems. For example, readers will learn how stability criteria can be used to gain new insights into the regulation of biological pathways and lung mechanics. They'll also learn how the concept of a time constant is used to capture the dynamics of diffusive processes. Readers will also master such topics as external disturbances, transfer functions, and input/output models with the support of the author's clear explanations, as well as:Detailed examples from the biological sciences and novel drug delivery technologies160 end-of-chapter problems with step-by-step solutionsDemonstrations of how computational software such as MATLAB and Mathematica solve complex drug delivery problemsControl of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering is written primarily for undergraduate chemical and biomedical engineering students; however, it is also recommended for students and researchers in pharmaceutical engineering, process control, and systems biology. All readers will gain a new perspective on process dynamics and control theory that will enable them to develop new and better technologies and therapeutics to treat human disease.
Thoroughly revised and updated to reflect current and emerging practices, this book explores modern methods of disease control in field and glasshouse crops. It outlines the major crop diseases, with a particular emphasis on those features of symptomology and life cycle that are most relevant to the development of control measures. Modern diagnostic techniques are considered, focusing on developments in nucleic acid and immunological based procedures and their use in plant quarantine and certification schemes. The potential impact of these advances in molecular technology on plant breeding and disease resistance is also covered. Fungicides are a central part of disease control in the EU and, as such, a comprehensive account of their use forms an important part of the text, along with strategies to minimise the incidence of fungicide resistance in pathogen populations. Looking to the future, the book also addresses legislative, environmental and food safety concerns.
Upon infection the host needs to mount vigorous immune response against pathogen in order to successfully control its replication. However, once the infectious agent is controlled or eliminated, host cells need to signal the immune system to slow or cease its activities. While vast knowledge has been accumulated through the years on the mechanisms involved in the initiation and effector phases of the immune responses, the pathways triggered in order to modulate or end innate and acquired immunity are becoming more evident as evidence for its relevance comes to surface. Due to its biological power, evidence has surfaced indicating that eventually pathogens may take advantage of such regulatory pathways in order to escape effector mechanisms and progress to persistence. This book will discuss several cellular pathways involved in controlling immune response in the context of infectious diseases, their biological consequences and potential "hijack" of these pathways for the benefit of pathogen leading towards pathogen persistence as opposed to clearance.
Control of Integral Processes with Dead Time provides a unified and coherent review of the various approaches devised for the control of integral processes, addressing the problem from different standpoints. In particular, the book treats the following topics: How to tune a PID controller and assess its performance; How to design a two-degree-of-freedom control scheme in order to deal with both the set-point following and load disturbance rejection tasks; How to modify the basic Smith predictor control scheme in order to cope with the presence of an integrator in the process; and how to address the presence of large process dead times. The methods are presented sequentially, highlighting the evolution of their rationale and implementation and thus clearly characterising them from both academic and industrial perspectives.
Control of Linear Parameter Varying Systems compiles state-of-the-art contributions on novel analytical and computational methods for addressing system identification, model reduction, performance analysis and feedback control design and addresses address theoretical developments, novel computational approaches and illustrative applications to various fields. Part I discusses modeling and system identification of linear parameter varying systems, Part II covers the importance of analysis and control design when working with linear parameter varying systems (LPVS) , Finally, Part III presents an applications based approach to linear parameter varying systems, including modeling of a turbocharged diesel engines, Multivariable control of wind turbines, modeling and control of aircraft engines, control of an autonomous underwater vehicles and analysis and synthesis of re-entry vehicles.
These three essays center around man's influence on nature and how it (nature) fights back. The First essay centers on New Orleans and how man's influence has contributed to it's now demise. Though written in 1989, Mcphee's research pretty much describes how Katrina, or in the case of the book, a theoretical storm, could have been made much less destructive had development been much less. The second article discusses efforts in Iceland to cool lava with saltwater and stop the destruction of a town. The third describes Los Angeles's expansion and possible demise due to run off and mud slides from the San Gabriel mountains. His premise in all three articles basically is, nature will ultimately have the last word in it's ultimate design.
Control of Solar Energy Systems details the main solar energy systems, problems involved with their control, and how control systems can help in increasing their efficiency. Thermal energy systems are explored in depth, as are photovoltaic generation and other solar energy applications such as solar furnaces and solar refrigeration systems. This second and updated edition of Advanced Control of Solar Plants includes new material on: solar towers and solar tracking; heliostat calibration, characterization and offset correction; solar radiation, estimation, prediction, and computation; and integrated control of solar plants. This new edition contains worked examples in the text as well as proposed exercises and simulation models and so will be of great use to the student and academic, as well as the industrial practitioner.
Surge Control of Active-magnetic-bearing-suspended Centrifugal Compressors sets out the fundamentals of integrating active magnetic bearing (AMB) rotor suspension technology in compressor systems, and describes how this relatively new bearing technology can be employed in active control of compressor surge initiation. The authors provide a self-contained and comprehensive review of rotordynamics and the fundamentals of AMB technology. The active stabilization of compressor surge employing AMBs in a machine is fully explored, from modeling of instability and controller design, to the implementation and experimental testing of the control algorithm in a specially-constructed, industrial-size centrifugal compression system. The results of these tests demonstrate the great potential of the new surge control method suggested in this text. This book will be useful for engineers in industries that involve turbocompressors and magnetic bearings, as well as for researchers and graduate students in the field of applied control. Whatever their level of experience, engineers working in the fields of turbomachinery, magnetic bearings, rotordynamics and controls will find the material in this book absorbing as all these important aspects of engineering are integrated to create a multi-disciplinary solution to a real-life industrial problem and the book is a suitable introduction to the area for newcomers.
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This revised edition incorporates the latest research to provide a comprehensive and up-to-date overview of controlled and modified atmosphere storage.
Cost and schedule growth is a problem experienced by many types of projects in many fields of endeavor. Based on prior studies of cost growth in NASA and Department of Defense projects,this book identifies specific causes of cost growth associated with NASA Earth and space science missions and provides guidance on how NASA can overcome these specific problems. The recommendations in this book focus on changes in NASA policies that would directly reduce or eliminate the cost growth of Earth and space science missions. Large cost growth is a concern for Earth and space science missions,and it can be a concern for other missions as well. If the cost growth is large enough,it can create liquidity problems for NASA's Science Mission Directorate that in turn cause cost profile changes and development delays that amplify the overall cost growth for other concurrent and/or pending missions. Addressing cost growth through the allocation of artificially high reserves is an inefficient use of resources because it unnecessarily diminishes the portfolio of planned flights. The most efficient use of resources is to establish realistic budgets and reserves and effective management processes that maximize the likelihood that mission costs will not exceed reserves. NASA is already taking action to reduce cost growth; additional steps,as recommended herein,will help improve NASA's mission planning process and achieve the goal of ensuring frequent mission opportunities for NASA Earth and space science.
As part of its Physics 2010 decadal survey, the NRC has undertaken a study of opportunities in atomic, molecular, and optical (AMO) science and technology over roughly the next decade. This study has been requested by the Department of Energy and the National Science Foundation. They asked the NRC to assess the state of AMO science, emphasizing recent accomplishments and identifying new and compelling scientific questions. A final report on this study is expected in the summer 2006. This interim report provides a preview of the final document. It presents a summary of the key opportunities in forefront AMO science and in closely related technologies, and a discussion of some of the broad-scale conclusions of the final report. The interim report also describes how AMO science supports national R&D priorities.
As part of the Physics 2010 decadal survey project, the Department of Energy and the National Science Foundation requested that the National Research Council assess the opportunities, over roughly the next decade, in atomic, molecular, and optical (AMO) science and technology. In particular, the National Research Council was asked to cover the state of AMO science, emphasizing recent accomplishments and identifying new and compelling scientific questions. Controlling the Quantum World, discusses both the roles and challenges for AMO science in instrumentation; scientific research near absolute zero; development of extremely intense x-ray and laser sources; exploration and control of molecular processes; photonics at the nanoscale level; and development of quantum information technology. This book also offers an assessment of and recommendations about critical issues concerning maintaining U.S. leadership in AMO science and technology.
McConachie (anesthesia and perioperative medicine, U. of Western Ontario, Canada) assembles 21 articles by obstetrics practitioners caring for high-risk patients at the University of Western Ontario and in the UK who outline debates in obstetric anesthesia and analgesia used in the perioperative and perinatal periods, for trainees and practitioners in anesthesia, obstetrics, and critical care medicine, as well as nurses and midwives. They address substance abuse and cardiac disease in pregnancy; management of pre-eclampsia and eclampsia, hemorrhage, and postdural puncture headache; anesthetic drugs and the developing fetal brain; ultrasound-guided epidural anesthesia, combined spinal-epidural anesthesia, and other types; coagulation and regional anesthesia; ambulatory and patient-controlled epidural analgesia; hypotension following spinal anesthesia; outcomes; cesarean section airway management, oxygen supplementation, oxytocin use and dosage, and analgesia; and other topics. Basic knowledge and experience in obstetric physiology, pharmacology, and anesthesia is assumed. Annotation ©2012 Book News, Inc. , Portland, OR (booknews. com)
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