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Mathematical Methods for Accident Reconstruction: A Forensic Engineering Perspective
by Harold Franck Darren FranckThis book demonstrates the application of mathematics to modeling accident reconstructions involving a range of moving vehicles, including automobiles, small and large trucks, bicycles, motorcycles, all‑terrain vehicles, and construction equipment, such as hoists and cranes.The book is anchored on the basic principles of physics that may be applied to any of the above‑named vehicles or equipment. Topics covered include the foundations of measurement, the various energy methods used in reconstruction, momentum methods, vehicle specifications, failure analysis, geometrical characteristics of highways, and softer scientific issues, such as visibility, perception, and reaction. The authors examine the fundamental characteristics of different vehicles, discuss the retrieval of data from crash data recorders, and review low‑speed impacts with an analysis of staged collisions. Finally, it details established standards and protocols for accident reconstruction for use in both investigations and in the courtroom. In addition, this new edition covers nonvehicle‑related topics like slip and fall analysis, fall protection, and engine and mechanical failure, as well as federal rules and laws that have been established for the work environment. Many reconstructions of incidents require extensive analysis that may require a variety of methods in order to properly model the incident.Exploring a broad range of accident scenarios, the breadth and depth of this book’s coverage makes Mathematical Methods for Accident Reconstruction, Second Edition, a critical reference for engineers and scientists who perform vehicular accident reconstructions.
Mathematical Methods for Life Sciences
by Rita Fioresi Cinzia BisiMathematical Methods for Life Sciences introduces calculus, and other key mathematical methods, to students from applied sciences (biology, biotechnology, chemistry, pharmacology, material science, etc). Special attention is paid to real-world applications, and for every concept, many concrete examples are provided. The book does not aim to enable students to prove theorems and construct elaborate proofs, but rather to leave students with a clear understanding of the practical mathematics behind the power of optimization, dynamical systems, and all the predictive tools these theories give rise to.Features No prerequisites beyond high school algebra and geometry Could serve as the primary text for a first-year course in mathematical methods for biology, biotechnology, or other life sciences Easy to read: the students may skip all the proofs and go directly to key examples and applications Cinzia Bisi is a professor of Geometry at the Department of Mathematics and Computer Sciences at the University of Ferrara, Italy. She has wide experience in teaching mathematics and statistics to students in the Department of Life Sciences. She has an interest in the areas of pure and applied mathematics. Rita Fioresi is a professor of Geometry at the FaBiT Department at the University of Bologna, Italy. She has written textbooks in linear algebra, and her research interests are primarily in the areas of pure and applied mathematics. .
Mathematical Methods for Optical Physics and Engineering
by Gregory J. Gbur"The first textbook on mathematical methods focusing on techniques for optical science and engineering, this text is ideal for upper division undergraduate and graduate students in optical physics. Containing detailed sections on the basic theory, the textbook places strong emphasis on connecting the abstract mathematical concepts to the optical systems to which they are applied. It covers many topics which usually only appear in more specialized books, such as Zernike polynomials, wavelet and fractional Fourier transforms, vector spherical harmonics, the z-transform, and the angular spectrum representation. Most chapters end by showing how the techniques covered can be used to solve an optical problem. Essay problems based on research publications and numerous exercises help to further strengthen the connection between the theory and its applications"--
Mathematical Methods for Physicists and Engineers: Second Corrected Edition
by Royal Eugene CollinsThis practical, highly readable text provides physics and engineering students with the essential mathematical tools for thorough comprehension of their disciplines. Featuring all the necessary topics in applied mathematics in the form of programmed instruction, the text can be understood by advanced undergraduates and beginning graduate students without any assistance from the instructor. Topics include elementary vector calculus, matrix algebra, and linear vector operations; the many and varied methods of solving linear boundary value problems, including the more common special functions of mathematical physics; the calculus of variations, and variational and perturbation approximations applicable to boundary value problems and nonlinear differential equations; curve fitting and numerical approximation methods; the basic elements of probability and their application to physical problems; and integral equations. Rather than aiming at a complete mastery of these complicated subjects, the text focuses on the fundamental applied mathematics the student needs to deal with physics and engineering problems. Instructors in those subjects will particularly appreciate this volume's function as a self-contained study resource, allowing them to devote fewer classroom hours to formal lectures in mathematics.
Mathematical Methods for Physics using Microsoft EXCEL
by Shinil ChoIn Mathematical Methods for Physics using Microsoft Excel, readers will investigate topics from classical to quantum mechanics, which are often omitted from the course work. Some of these topics include rocket propulsion, Rutherford scattering, precession and nutation of a top under gravity, parametric oscillation, relativistic Doppler effect, concepts of entropy, kinematics of wave packets, and boundary value problems and associated special functions as orthonormal bases. Recent topics such as the Lagrange point of the James Webb Space Telescope, a muon detector in relation to Cherenkov’s radiation, and information entropy and H-function are also discussed and analyzed. Additional interdisciplinary topics, such as self-avoiding random walks for polymer length and population dynamics, are also described.This book will allow readers to reproduce and replicate the data and experiments often found in physics textbooks, with a stronger foundation of knowledge. While investigating these subjects, readers will follow a step-by-step introduction to computational algorithms for solving differential equations for which analytical solutions are often challenging to find. For computational analysis, features of Microsoft Excel® including AutoFill, Iterative Calculation, and Visual Basic for Applications are useful to conduct hands-on projects. For the visualization of computed outcomes, the Chart output feature can be readily used. There are several first-time attempts on various topics introduced in this book such as 3D-like graphics using Euler’s angle and the behavior of wave functions of harmonic oscillators and hydrogen atoms near the true eigenvalues.
Mathematical Methods for Physics: 45th anniversary edition
by H.W. Wyld Gary PowellFrom classical mechanics and classical electrodynamics to modern quantum mechanics many physical phenomena are formulated in terms of similar partial differential equations while boundary conditions determine the specifics of the problem. This 45th anniversary edition of the advanced book classic Mathematical Methods for Physics demonstrates how many physics problems resolve into similar inhomogeneous partial differential equations and the mathematical techniques for solving them. The text has three parts: Part I establishes solving the homogenous Laplace and Helmholtz equations in the three main coordinate systems, rectilinear, cylindrical, and spherical and develops the solution space for series solutions to the Sturm-Liouville equation, indicial relations, and the expansion of orthogonal functions including spherical harmonics and Fourier series, Bessel, and Spherical Bessel functions. Many examples with figures are provided including electrostatics, wave guides and resonant cavities, vibrations of membranes, heat flow, potential flow in fluids, and plane and spherical waves. In Part II the inhomogeneous equations are addressed where source terms are included for Poisson's equation, the wave equation, and the diffusion equation. Coverage includes many examples from averaging approaches for electrostatics and magnetostatics, from Green function solutions for time independent and time dependent problems, and from integral equation methods. In Part III complex variable techniques are presented for solving integral equations involving Cauchy Residue theory, contour methods, analytic continuation, and transforming the contour; for addressing dispersion relations; for revisiting special functions in the complex plane; and for transforms in the complex plane including Green’s functions and Laplace transforms.Key Features: Mathematical Methods for Physics creates a strong, solid anchor of learning and is useful for reference Lecture note style suitable for advanced undergraduate and graduate students to learn many techniques for solving partial differential equations with boundary conditions Many examples across various subjects of physics in classical mechanics, classical electrodynamics, and quantum mechanics Updated typesetting and layout for improved clarity This book, in lecture note style with updated layout and typesetting, is suitable for advanced undergraduate, graduate students, and as a reference for researchers. It has been edited and carefully updated by Gary Powell.
Mathematical Methods in Chemical and Biological Engineering
by Binay Kanti DuttaMathematical Methods in Chemical and Biological Engineering describes basic to moderately advanced mathematical techniques useful for shaping the model-based analysis of chemical and biological engineering systems. Covering an ideal balance of basic mathematical principles and applications to physico-chemical problems, this book presents examples drawn from recent scientific and technical literature on chemical engineering, biological and biomedical engineering, food processing, and a variety of diffusional problems to demonstrate the real-world value of the mathematical methods. Emphasis is placed on the background and physical understanding of the problems to prepare students for future challenging and innovative applications.
Mathematical Methods in Elasticity Imaging
by Elie Bretin Abdul Wahab Hyeonbae Kang Habib Ammari Hyundae Lee Josselin GarnierThis book is the first to comprehensively explore elasticity imaging and examines recent, important developments in asymptotic imaging, modeling, and analysis of deterministic and stochastic elastic wave propagation phenomena. It derives the best possible functional images for small inclusions and cracks within the context of stability and resolution, and introduces a topological derivative-based imaging framework for detecting elastic inclusions in the time-harmonic regime. For imaging extended elastic inclusions, accurate optimal control methodologies are designed and the effects of uncertainties of the geometric or physical parameters on stability and resolution properties are evaluated. In particular, the book shows how localized damage to a mechanical structure affects its dynamic characteristics, and how measured eigenparameters are linked to elastic inclusion or crack location, orientation, and size. Demonstrating a novel method for identifying, locating, and estimating inclusions and cracks in elastic structures, the book opens possibilities for a mathematical and numerical framework for elasticity imaging of nanoparticles and cellular structures.
Mathematical Methods in Engineering: Applications in Dynamics of Complex Systems (Nonlinear Systems and Complexity #24)
by Dumitru Baleanu Kenan Taş J. A. MachadoThis book presents recent developments in nonlinear dynamics with an emphasis on complex systems. The volume illustrates new methods to characterize the solutions of nonlinear dynamics associated with complex systems. This book contains the following topics: new solutions of the functional equations, optimization algorithm for traveling salesman problem, fractals, control, fractional calculus models, fractional discretization, local fractional partial differential equations and their applications, and solutions of fractional kinetic equations.
Mathematical Methods in Engineering: Theoretical Aspects (Nonlinear Systems and Complexity #23)
by Dumitru Baleanu Kenan Taş J. A. MachadoThis book collects chapters dealing with some of the theoretical aspects needed to properly discuss the dynamics of complex engineering systems. The book illustrates advanced theoretical development and new techniques designed to better solve problems within the nonlinear dynamical systems. Topics covered in this volume include advances on fixed point results on partial metric spaces, localization of the spectral expansions associated with the partial differential operators, irregularity in graphs and inverse problems, Hyers-Ulam and Hyers-Ulam-Rassias stability for integro-differential equations, fixed point results for mixed multivalued mappings of Feng-Liu type on Mb-metric spaces, and the limit q-Bernstein operators, analytical investigation on the fractional diffusion absorption equation.
Mathematical Methods in Physics and Engineering (Dover Books on Physics)
by John W. DettmanIntended for college-level physics, engineering, or mathematics students, this volume offers an algebraically based approach to various topics in applied math. It is accessible to undergraduates with a good course in calculus which includes infinite series and uniform convergence. Exercises follow each chapter to test the student's grasp of the material; however, the author has also included exercises that extend the results to new situations and lay the groundwork for new concepts to be introduced later. A list of references for further reading will be found at the end of each chapter. For this second revised edition, Professor Dettman included a new section on generalized functions to help explain the use of the Dirac delta function in connection with Green's functions. In addition, a new approach to series solutions of ordinary differential equations has made the treatment independent of complex variable theory. This means that the first six chapters can be grasped without prior knowledge of complex variables. However, since Chapter 8 depends heavily on analytic functions of a complex variable, a new Chapter 7 on analytic function theory has been written.
Mathematical Methods in Robust Control of Linear Stochastic Systems
by Vasile Dragan Toader Morozan Adrian-Mihail StoicaThis second edition of Mathematical Methods in the Robust Control of Linear Stochastic Systems includes a large number of recent results in the control of linear stochastic systems. More specifically, the new results presented are: - A unified and abstract framework for Riccati type equations arising in the stochastic control - Stability and control problems for systems perturbed by homogeneous Markov processes with infinite number of states - Mixed H2 / H∞ control problem and numerical procedures - Linear differential equations with positive evolution on ordered Banach spaces with applications for stochastic systems including both multiplicative white noise and Markovian jumps represented by a Markov chain with countable infinite set of states - Kalman filtering for stochastic systems subject both to state dependent noise and Markovian jumps - H∞ reduced order filters for stochastic systems The book will appeal to graduate students, researchers in advanced control engineering, finance, mathematical systems theory, applied probability and stochastic processes, and numerical analysis. From Reviews of the First Edition: This book is concerned with robust control of stochastic systems. One of the main features is its coverage of jump Markovian systems. . . . Overall, this book presents results taking into consideration both white noise and Markov chain perturbations. It is clearly written and should be useful for people working in applied mathematics and in control and systems theory. The references cited provide further reading sources. (George Yin, Mathematical Reviews, Issue 2007 m) This book considers linear time varying stochastic systems, subjected to white noise disturbances and system parameter Markovian jumping, in the context of optimal control . . . robust stabilization, and disturbance attenuation. . . . The material presented in the book is organized in seven chapters. . . . The book is very well written and organized. . . . is a valuable reference for all researchers and graduate students in applied mathematics and control engineering interested in linear stochastic time varying control systems with Markovian parameter jumping and white noise disturbances. (Zoran Gajic, SIAM Review, Vol. 49 (3), 2007)
Mathematical Methods in the Physical Sciences (Third Edition)
by Mary L. BoasNow in its third edition, Mathematical Concepts in the Physical Sciences, 3rd Edition provides a comprehensive introduction to the areas of mathematical physics. It combines all the essential math concepts into one compact, clearly written reference. This book is intended for students who have had a two-semester or three-semester introductory calculus course. Its purpose is to help students develop, in a short time, a basic competence in each of the many areas of mathematics needed in advanced courses in physics, chemistry, and engineering. Students are given sufficient depth to gain a solid foundation (this is not a recipe book). At the same time, they are not overwhelmed with detailed proofs that are more appropriate for students of mathematics. The emphasis is on mathematical methods rather than applications, but students are given some idea of how the methods will be used along with some simple applications.
Mathematical Methods of Many-Body Quantum Field Theory (Chapman & Hall/CRC Research Notes in Mathematics Series)
by Detlef LehmannMathematical Methods of Many-Body Quantum Field Theory offers a comprehensive, mathematically rigorous treatment of many-body physics. It develops the mathematical tools for describing quantum many-body systems and applies them to the many-electron system. These tools include the formalism of second quantization, field theoretical perturbation theo
Mathematical Methods using Python: Applications in Physics and Engineering
by Vasilis Pagonis Christopher Wayne KulpThis advanced undergraduate textbook presents a new approach to teaching mathematical methods for scientists and engineers. It provides a practical, pedagogical introduction to utilizing Python in Mathematical and Computational Methods courses. Both analytical and computational examples are integrated from its start. Each chapter concludes with a set of problems designed to help students hone their skills in mathematical techniques, computer programming, and numerical analysis. The book places less emphasis on mathematical proofs, and more emphasis on how to use computers for both symbolic and numerical calculations. It contains 182 extensively documented coding examples, based on topics that students will encounter in their advanced courses in Mechanics, Electronics, Optics, Electromagnetism, Quantum Mechanics etc.An introductory chapter gives students a crash course in Python programming and the most often used libraries (SymPy, NumPy, SciPy, Matplotlib). This is followed by chapters dedicated to differentiation, integration, vectors and multiple integration techniques. The next group of chapters covers complex numbers, matrices, vector analysis and vector spaces. Extensive chapters cover ordinary and partial differential equations, followed by chapters on nonlinear systems and on the analysis of experimental data using linear and nonlinear regression techniques, Fourier transforms, binomial and Gaussian distributions. The book is accompanied by a dedicated GitHub website, which contains all codes from the book in the form of ready to run Jupyter notebooks. A detailed solutions manual is also available for instructors using the textbook in their courses.Key Features:· A unique teaching approach which merges mathematical methods and the Python programming skills which physicists and engineering students need in their courses.· Uses examples and models from physical and engineering systems, to motivate the mathematics being taught.· Students learn to solve scientific problems in three different ways: traditional pen-and-paper methods, using scientific numerical techniques with NumPy and SciPy, and using Symbolic Python (SymPy).Vasilis Pagonis is Professor of Physics Emeritus at McDaniel College, Maryland, USA. His research area is applications of thermally and optically stimulated luminescence. He taught courses in mathematical physics, classical and quantum mechanics, analog and digital electronics and numerous general science courses. Dr. Pagonis’ resume lists more than 200 peer-reviewed publications in international journals. He is currently associate editor of the journal Radiation Measurements. He is co-author with Christopher Kulp of the undergraduate textbook “Classical Mechanics: a computational approach, with examples in Python and Mathematica” (CRC Press, 2020). He has also co-authored four graduate-level textbooks in the field of luminescence dosimetry, and most recently published the book “Luminescence Signal analysis using Python” (Springer, 2022).Christopher Kulp is the John P. Graham Teaching Professor of Physics at Lycoming College. He has been teaching undergraduate physics at all levels for 20 years. Dr. Kulp’s research focuses on modelling complex systems, time series analysis, and machine learning. He has published 30 peer-reviewed papers in international journals, many of which include student co-authors. He is also co-author of the undergraduate textbook “Classical Mechanics: a computational approach, with examples in Python and Mathematica” (CRC Press, 2020).
Mathematical Modeling
by Peter Knabner Christof Eck Harald GarckeThe main aim of this paper is to present some new and general results, ap plicable to the the equations of two phase flow, as formulated in geothermal reservoir engineering. Two phase regions are important in many geothermal reservoirs, especially at depths of order several hundred metres, where ris ing, essentially isothermal single phase liquid first begins to boil. The fluid then continues to rise, with its temperature and pressure closely following the saturation (boiling) curve appropriate to the fluid composition. Perhaps the two most interesting theoretical aspects of the (idealised) two phase flow equations in geothermal reservoir engineering are that firstly, only one component (water) is involved; and secondly, that the densities of the two phases are so different. This has led to the approximation of ignoring capillary pressure. The main aim of this paper is to analyse some of the consequences of this assumption, especially in relation to saturation changes within a uniform porous medium. A general analytic treatment of three dimensional flow is considered. Pre viously, three dimensional modelling in geothermal reservoirs have relied on numerical simulators. In contrast, most of the past analytic work has been restricted to one dimensional examples.
Mathematical Modeling Of Melting And Freezing Processes
by V. AlexiadesThis reference book presents mathematical models of melting and solidification processes that are the key to the effective performance of latent heat thermal energy storage systems (LHTES), utilized in a wide range of heat transfer and industrial applications. This topic has spurred a growth in research into LHTES applications in energy conservation and utilization, space station power systems, and thermal protection of electronic equipment in hostile environments. Further, interest in mathematical modeling has increased with the speread of high powered computers used in most industrial and academic settings. In two sections, the book first describes modeling of phase change processes and then describes applications for LHTES. It is aimed at graduate students, researchers, and practicing engineers in heat transfer, materials processing, multiphase systems, energy conservation, metallurgy, microelectronics, and cryosurgery.
Mathematical Modeling Through Topological Surgery and Applications (Springer Theses)
by Stathis AntoniouTopological surgery is a mathematical technique used for creating new manifolds out of known ones. In this book the authors observe that it also occurs in natural phenomena of all scales: 1-dimensional surgery happens during DNA recombination and when cosmic magnetic lines reconnect; 2-dimensional surgery happens during tornado formation and cell mitosis; and they conjecture that 3-dimensional surgery happens during the formation of black holes from cosmic strings, offering an explanation for the existence of a black hole’s singularity. Inspired by such phenomena, the authors present a new topological model that extends the formal definition to a continuous process caused by local forces. Lastly, they describe an intrinsic connection between topological surgery and a chaotic dynamical system exhibiting a “hole drilling” behavior. The authors’ model indicates where to look for the forces causing surgery and what deformations should be observed in the local submanifolds involved. These predictions are significant for the study of phenomena exhibiting surgery and they also open new research directions. This novel study enables readers to gain a better understanding of the topology and dynamics of various natural phenomena, as well as topological surgery itself and serves as a basis for many more insightful observations and new physical implications.
Mathematical Modeling and Applications in Nonlinear Dynamics
by Albert C.J. Luo Hüseyin MerdanThe book covers nonlinear physical problems and mathematical modeling, including molecular biology, genetics, neurosciences, artificial intelligence with classical problems in mechanics and astronomy and physics. The chapters present nonlinear mathematical modeling in life science and physics through nonlinear differential equations, nonlinear discrete equations and hybrid equations. Such modeling can be effectively applied to the wide spectrum of nonlinear physical problems, including the KAM (Kolmogorov-Arnold-Moser (KAM)) theory, singular differential equations, impulsive dichotomous linear systems, analytical bifurcation trees of periodic motions, and almost or pseudo- almost periodic solutions in nonlinear dynamical systems.
Mathematical Modeling and Control in Life and Environmental Sciences: Regional Control Problems (Modeling and Simulation in Science, Engineering and Technology)
by Sebastian Aniţa Vincenzo Capasso Simone ScacchiThis monograph explores the use of mathematical modeling and control theory in a variety of contemporary challenges in mathematical biology and environmental sciences. Emphasizing an approach of learning by doing, the authors focus on a set of significant case studies emerging from real-world problems and illustrate how mathematical techniques and computational experiments can be employed in the search for sustainable solutions.The following topics are extensively discussed:Eradicability and control of a paradigmatic epidemic model, with a view to the existence of endemic states, their stability, and the existence of travelling wavesA spatially structured epidemic model concerning malaria as an example of vector-borne epidemicsOptimal harvesting problems for space-structured and age-structured population dynamicsControlling epidemics in agriculture due to pest insectsThe role of predators as a possible biocontrol agent of epidemics in agricultureControl by taxation of the environmental pollution produced by human activitiesThe originality of this text is in its leitmotif – regional control – along the principle of “Think Globally, Act Locally.” Indeed, for example, in many real spatially structured ecosystems, it is practically impossible to control the relevant system by global interventions in the whole habitat.Proofs are given whenever they may serve as a guide to the introduction of new concepts. Each chapter includes a comprehensive description of the numerical methods used for the computational experiments, and MATLAB© codes for many of the numerical simulations are available for download. Several challenging open problems are also provided to stimulate future research.This text is aimed at mathematicians, engineers, and other scientists working in areas such as biology, medicine, and economics. Graduate and advanced undergraduate students of a quantitative subject related to the analysis and applications of dynamical systems and their control will also find it to be a valuable resource.
Mathematical Modeling and Intelligent Control for Combating Pandemics (Springer Optimization and Its Applications #203)
by Dumitru Baleanu Zakia Hammouch Mohamed LahbyThe contributions in this carefully curated volume, present cutting-edge research in applied mathematical modeling for combating COVID-19 and other potential pandemics. Mathematical modeling and intelligent control have emerged as powerful computational models and have shown significant success in combating any pandemic. These models can be used to understand how COVID-19 or other pandemics can spread, analyze data on the incidence of infectious diseases, and predict possible future scenarios concerning pandemics. This book also discusses new models, practical solutions, and technological advances related to detecting and analyzing COVID-19 and other pandemics based on intelligent control systems that assist decision-makers, managers, professionals, and researchers. Much of the book focuses on preparing the scientific community for the next pandemic, particularly the application of mathematical modeling and intelligent control for combating the Monkeypox virus and Langya Henipavirus.
Mathematical Modeling and Numerical Techniques in Drying Technology
by Arun S. Mujumdar Ian TurnerOffers information necessary for the development of mathematical models and numerical techniques to solve specific drying problems. The book addresses difficult issues involved with the drying equations of numerical analysis, including mesh generation, discretinization strategies, the nonlinear equation set and the linearized algebraic system, convergance criteria, time step control, experimental validation, optimum methods of visualization results, and more.
Mathematical Modeling and Optimization of Complex Structures
by Pekka Neittaanmäki Tero Tuovinen Sergey RepinThis volume contains selected papers in three closely related areas: mathematical modeling in mechanics, numerical analysis, and optimization methods. The papers are based upon talks presented on the International Conference for Mathematical Modeling and Optimization in Mechanics, held in Jyväskylä, Finland, March 6-7, 2014 dedicated to Prof. N. Banichuk on the occasion of his 70th birthday. The articles are written by well-known scientists working in computational mechanics and in optimization of complicated technical models. Also, the volume contains papers discussing the historical development, the state of the art, new ideas, and open problems arising in modern continuum mechanics and applied optimization problems. Several papers are concerned with mathematical problems in numerical analysis, which are also closely related to important mechanical models. The main topics treated include: * Computer simulation methods in mechanics, physics, and biology; * Variational problems and methods; minimization algorithms; * Optimal control problems with distributed and discrete control; * Shape optimization and shape design problems in science and engineering; * Sensitivity analysis and parameters optimization of complex systems.
Mathematical Modeling and Scale-Up of Liquid Chromatography
by Tingyue GuTingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced since the first edition of this book and the author's software, described here, is now used for teaching and research in 32 different countries. This book comes together with a complete software package with graphical user interface for personal computers, offered free for academic applications. Additionally, this book provides detailed methods for parameter estimation of mass transfer coefficients, bed voidage, particle porosity and isotherms. The author gives examples of how to use the software for predicitons and scale-up. In contrast to the first edition, authors do not need to deal with complicated math. Instead, they focus on how to obtain a few parameters for simulation and how to compare simulation results with experimental data. After reading the detailed descriptions in the book, a reader is able to use the simulation software to investigate chromatographic behavior without doing actual experiments. This book is aimed at readers who are interested in learning about LC behaviors and at those who want to scale up LC for preparative- and large-scale applications. Both academic personnel and industrial practitioners can benefit from the use of the book. This new edition includes: - New models and software for pellicular (cored) beads in liquid chromatography - Introduction of user-friendly software (with graphical user interface) - Detailed descriptions on how to use the software - Step-by-step instructions on parameter estimation for the models - New mass-transfer correlations for parameter estimation - Experimental methods for parameter estimation - Several actual examples using the model for product development and scale-up - Updated literature review
Mathematical Modeling and Validation in Physiology
by Mostafa Bachar Jerry J. Batzel Franz KappelThis volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.