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Metagenomics of the Human Body
by Karen E. NelsonThe book brings a completely different perspective than available books by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. Although there are a number of books that focus on the human genome that are currently available, there are no books that bring to the forefront the mix of the human genome and the genomes and metagenomes of the microbial species that live within and on us.
Metagenomics: Methods and Protocols (Methods in Molecular Biology #2555)
by Rolf Daniel Wolfgang R. StreitThis volume provides up-to-date and novel techniques for various screening technologies currently used in metagenomics and related areas. Starting with DNA/RNA isolation from environmental samples, the book continues by delving into areas such as current methods used to isolate DNA and construct metagenomic libraries, establishment of metagenome libraries in non-E. coli hosts, and topics like function-driven mining of metagenomic DNA, screening and analyzing protocols for a wide array of different genes encoding enzymes, bacterial viruses and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Metagenomics: Methods and Protocols, Third Edition provides a comprehensive collection of up-to-date metagenome protocols and tools for the recovery of many major types of biocatalysts and allows for the easy setup of these screens in microbiology laboratories.
Metagenomics: Techniques, Applications, Challenges and Opportunities
by Neeta Raj Sharma Reena Singh Chopra Chirag ChopraThis book summarizes the various areas of research in metagenomics and their potential applications in medicine, the environment and biotechnology. The book presents the recent advances in theoretical, methodological and applied aspects of metagenomics and highlights their applications in the fields of environmental microbial forensics, bioremediation, drug-discovery and agriculture. In addition, the book discusses various metagenomics approaches used for understanding the microbial physiology and biochemistry. Lastly the book describes a range of bioinformatics tools and computational methods for metagenomics analysis as well as the functional diversity and dynamics of microbial communities colonizing the human skin.
Metagovernance for Sustainability: A Framework for Implementing the Sustainable Development Goals (Routledge Studies in Sustainable Development)
by Louis MeulemanThe 17 Sustainable Development Goals (SDGs) which were adopted by the United Nations in September 2015 are universally applicable in all 193 UN Member States and connect the big challenges of our time, such as hunger and poverty, climate change, health in an urbanised environment, sustainable energy, mobility, economic development and environmental degradation. Sustainability has the characteristics of a ‘wicked problem’, for which there are no one-size-fits-all solutions. This book tests the hypothesis that the implementation of sustainable development, and in particular the 2015 SDGs, requires tailor-made metagovernance or ‘governance of governance’. This is necessary to develop effective governance and high quality and inclusive public administration and to foster policy and institutional coherence to support implementing the SDGs. Based on the growing literature on governance and metagovernance, and taking into account the specificities of societal factors such as different values and traditions in different countries, the book presents a framework for the design and management of SDG implementation. It shows how hierarchical, network and market governance styles can be combined and how governance failure can be prevented or dealt with. The book presents an overview of fifty ‘shades of governance’ which differ for each governance style, and a sketch of a concrete method to apply sustainability metagovernance. Metagovernance for Sustainability is relevant to academic and practitioner fields across many disciplines and problem areas. It will be of particular interest to scholars, students and policy-makers studying Sustainable Development, Governance and Metagovernance, Public Management and Capacity Building.
Metaheuristics for Resource Deployment under Uncertainty in Complex Systems
by Panos M. Pardalos Qi Zhang Chen Chen Shuxin Ding Bin XinMetaheuristics for Resource Deployment under Uncertainty in Complex Systems analyzes how to set locations for the deployment of resources to incur the best performance at the lowest cost. Resources can be static nodes and moving nodes while services for a specific area or for customers can be provided. Theories of modeling and solution techniques are used with uncertainty taken into account and real-world applications used. The authors present modeling and metaheuristics for solving resource deployment problems under uncertainty while the models deployed are related to stochastic programming, robust optimization, fuzzy programming, risk management, and single/multi-objective optimization. The resources are heterogeneous and can be sensors and actuators providing different tasks. Both separate and cooperative coverage of the resources are analyzed. Previous research has generally dealt with one type of resource and considers static and deterministic problems, so the book breaks new ground in its analysis of cooperative coverage with heterogeneous resources and the uncertain and dynamic properties of these resources using metaheuristics. This book will help researchers, professionals, academics, and graduate students in related areas to better understand the theory and application of resource deployment problems and theories of uncertainty, including problem formulations, assumptions, and solution methods.
Metahuman: Unleashing Your Infinite Potential
by Deepak ChopraIs it possible to venture beyond daily living and experience heightened states of awareness? In his latest book, Deepak Chopra says that higher consciousness is available here and now. “Metahuman helps us harvest peak experiences so we can see our truth and mold the universe’s chaos into a form that brings light to the world.”—Dr. Mehmet Oz, Attending Physician, New York–Presbyterian, Columbia University New York Times bestselling author Deepak Chopra unlocks the secrets to moving beyond our present limitations to access a field of infinite possibilities. How does one do this? By becoming metahuman. To be metahuman, however, isn’t science fiction and is certainly not about being a superhero. To be metahuman means to move past the limitation constructed by the mind and enter a new state of awareness where we have deliberate and concrete access to peak experiences that can transform people’s lives from the inside out. Humans do this naturally—to a point. For centuries the great artists, scientists, writers, and many so-called ordinary people have gone beyond the everyday physical world. But if we could channel these often bewildering experiences, what would happen? Chopra argues we would wake up to experiences that would blow open your body, mind, and soul. Metahuman invites the reader to walk the path here and now. Waking up, we learn, isn’t just about mindfulness or meditation. Waking up, to become metahuman, is to expand our consciousness in all that we think, say, and do. By going beyond, we liberate ourselves from old conditioning and all the mental constructs that underlie anxiety, tension, and ego-driven demands. Waking up allows life to make sense as never before. To make this as practical as possible, Chopra ends the book with a 31-day guide to becoming metahuman. Once you wake up, he writes, life becomes transformed, because pure consciousness—which is the field of all possibilities—dawns in your life. Only then does your infinite potential become your personal reality.Advance praise for Metahuman“Our world is preoccupied with material progress, yet too often we overlook the miracle of our very existence. In this remarkable book, Deepak Chopra reminds us not to be distracted by the idols of our age but to marvel at the deep truths of being. Metahuman is a handbook to becoming fully alive.”—Arthur C. Brooks, PhD, Professor, Harvard Kennedy School; author of Love Your Enemies
Metakaolin and Fly Ash as Mineral Admixtures for Concrete
by Leonid Dvorkin Vadim Zhitkovsky Yuri Ribakov Nataliya LushnikovaThe book deals with modern theoretical concepts related to the impact of fly ash and metakaolin admixtures on structure formation processes of concrete. Results of the effect of fly ash, metakaolin and their composition on properties of self-compacting and self-leveling concrete are presented. Based on mathematical models, obtained using mathematical experiments planning methodology, the impact of the main factors and their combination on workability, strength and other properties that determine efficiency and durability of concrete are analyzed. Using calculated dependencies, a methodology for designing optimal compositions of concrete containing active mineral admixtures and superplasticizers is proposed. Features of industrial production of concrete for the proposed compositions are discussed. The book is intended for specialists working in the production of concrete and reinforced concrete products and elements. It can also be used by construction engineers to design compositions of cost-effective self-compacting and self-leveling concrete as well as to determine the rational direction of using technogenic raw materials like ash and metakaolin.
Metal Additive Manufacturing
by Ehsan Toyserkani Dyuti Sarker Osezua Obehi Ibhadode Farzad Liravi Paola Russo Katayoon TaherkhaniMETAL ADDITIVE MANUFACTURING A comprehensive review of additive manufacturing processes for metallic structures Additive Manufacturing (AM)—also commonly referred to as 3D printing—builds three-dimensional objects by adding materials layer by layer. Recent years have seen unprecedented investment in additive manufacturing research and development by governments and corporations worldwide. This technology has the potential to replace many conventional manufacturing processes, enable the development of new industry practices, and transform the entire manufacturing enterprise. Metal Additive Manufacturing provides an up-to-date review of all essential physics of metal additive manufacturing techniques with emphasis on both laser-based and non-laser-based additive manufacturing processes. This comprehensive volume covers fundamental processes and equipment, governing physics and modelling, design and topology optimization, and more. The text adresses introductory, intermediate, and advanced topics ranging from basic additive manufacturing process classification to practical and material design aspects of additive manufacturability. Written by a panel of expert authors in the field, this authoritative resource: Provides a thorough analysis of AM processes and their theoretical foundations Explains the classification, advantages, and applications of AM processes Describes the equipment required for different AM processes for metallic structures, including laser technologies, positioning devices, feeder and spreader mechanisms, and CAD software Discusses the opportunities, challenges, and current and emerging trends within the field Covers practical considerations, including design for AM, safety, quality assurance, automation, and real-time control of AM processes Includes illustrative cases studies and numerous figures and tables Featuring material drawn from the lead author’s research and professional experience on laser additive manufacturing, Metal Additive Manufacturing is an important source for manufacturing professionals, research and development engineers in the additive industry, and students and researchers involved in mechanical, mechatronics, automatic control, and materials engineering and science.
Metal Catalyzed Cross-Coupling Reactions and More, 3 Volume Set
by Stefan Bräse Armin De Meijere Martin OestreichThis is the follow-up handbook to the bestselling Metal-Catalyzed Cross Coupling Reactions, the definitive reference in the field. In line with the enormous developments in this area, this is not so much a new edition, but rather a new book in three volumes with over 50% more content. This new content includes C-H activation, shifting the focus away from typical crosscoupling reactions, while those topics and chapters found in Diederich/de Meijere's book have been updated and expanded.With its highly experienced editor team and the authors reading like an international Who's-Who in the field, this handbook is of great interest to every synthetic chemist working in academia and industry.Take advantage of the introductory offer!Introductory price, valid until 30 April 2014: USD $540.00 / £325.00 / 399.00Thereafter: USD $605.00 / £365.00 / 449.00 From the reviews of the bestselling Metal-Catalyzed Cross Coupling Reactions:"... this book provides a very broad and interesting overview of what has been done in the particular field over the last years and every major advance is described and properly referenced. ... The chapters are all written by internationally recognized leaders in the field and are of uniformly high quality providing an excellent insight into the material." - Advanced Synthesis & Catalysis"... thoroughly referenced, consistently well written, clear and free from errors ...This is an absolutely essential reference work and it is highly recommended for anyone engaged in the field of organic synthesis." - Applied Organometallic Chemistry
Metal Clusters and Nanoalloys
by Marcelo Mario Mariscal Oscar Alejandro Oviedo Ezequiel Pedro LeivaMetallic nanoparticles hold promise for their potential applications in a wide array of disciplines ranging from materials science to medicine. This book brings the power of theoretical methods to an audience of experimentalists, and explicates the simulation of metallic clusters and nanoparticles. It begins with a summary of the current state of research on metallic nanoparticles, then moves on to the current state of the art in theory of metallic nanoparticldes, and then explains why and how these tools help experimentalists. Contributions are provided by renowned experts in the field from across the world.
Metal Clusters and Their Reactivity
by Zhixun Luo Shiv N. KhannaThis book discusses current techniques and instrumentation for cluster chemistry. It addresses both the experimental and theoretical aspects of gas-phase metal cluster reactivities, especially those pertaining to pollution removal, energetic reactions and corrosion and anticorrosion. These metal cluster systems have attracted enormous interest as they display a completely new class of physical, chemical, electronic, magnetic and catalytic properties. As these properties change with size and composition, it can thus be understood how their nature evolves from atoms to bulk solids. The book offers readers a basic understanding of the structural chemistry and reactivity of metal clusters in both gas-phase and wet chemistry. Further, the lessons they learn here regarding metal cluster chemistry will prepare researchers for the study of condensed phase dynamics that pertain to wet chemical synthesis, soft-landing deposition and cluster assembly.
Metal Contaminated Aquatic Sediments
by HerbertE. AllenOver the past decade the sediments of many rivers, lakes, and estuaries have been contaminated by inorganic and organic materials. Contaminants from sediments, under certain conditions, can be released into overlying waters. Thus, sediments may be an important source of contaminants to waters in which littoral and atmospheric contaminants have been reduced or eliminated.Often found in aquatic sediments, metals are exposed to many reactions, such as sorption and precipitation, and are greatly influenced by the redox conditions in the sediment. The reactions - usually over a period of time - reflect biotic processing as well as chemical transformations. This book describes these important processes. Metal Contaminated Aquatic Sediments outlines advances in environmental chemistry, effective new modeling techniques, applications for biological treatment, and cycling and transport of trace metals in sedimentary environments.Each chapter contains a detailed reference section that draws upon a stunning array of sources. The book includes many figures and tables that illustrate the process under discussion.Features
Metal Cutting Mechanics
by Viktor P. AstakhovMetal Cutting Mechanics outlines the fundamentals of metal cutting analysis, reducing the extent of empirical approaches to the problems as well as bridging the gap between design and manufacture. The author distinguishes his work from other works through these aspects:considering the system engineering of the cutting process id
Metal Cutting Theory and Practice
by David A. Stephenson John S. AgapiouA Complete Reference Covering the Latest Technology in Metal Cutting Tools, Processes, and Equipment Metal Cutting Theory and Practice, Third Edition shapes the future of material removal in new and lasting ways. Centered on metallic work materials and traditional chip-forming cutting methods, the book provides a physical understanding of conventional and high-speed machining processes applied to metallic work pieces, and serves as a basis for effective process design and troubleshooting. This latest edition of a well-known reference highlights recent developments, covers the latest research results, and reflects current areas of emphasis in industrial practice. Based on the authors’ extensive automotive production experience, it covers several structural changes, and includes an extensive review of computer aided engineering (CAE) methods for process analysis and design. Providing updated material throughout, it offers insight and understanding to engineers looking to design, operate, troubleshoot, and improve high quality, cost effective metal cutting operations. The book contains extensive up-to-date references to both scientific and trade literature, and provides a description of error mapping and compensation strategies for CNC machines based on recently issued international standards, and includes chapters on cutting fluids and gear machining. The authors also offer updated information on tooling grades and practices for machining compacted graphite iron, nickel alloys, and other hard-to-machine materials, as well as a full description of minimum quantity lubrication systems, tooling, and processing practices. In addition, updated topics include machine tool types and structures, cutting tool materials and coatings, cutting mechanics and temperatures, process simulation and analysis, and tool wear from both chemical and mechanical viewpoints. Comprised of 17 chapters, this detailed study: Describes the common machining operations used to produce specific shapes or surface characteristics Contains conventional and advanced cutting tool technologies Explains the properties and characteristics of tools which influence tool design or selection Clarifies the physical mechanisms which lead to tool failure and identifies general strategies for reducing failure rates and increasing tool life Includes common machinability criteria, tests, and indices Breaks down the economics of machining operations Offers an overview of the engineering aspects of MQL machining Summarizes gear machining and finishing methods for common gear types, and more Metal Cutting Theory and Practice, Third Edition emphasizes the physical understanding and analysis for robust process design, troubleshooting, and improvement, and aids manufacturing engineering professionals, and engineering students in manufacturing engineering and machining processes programs.
Metal Ecotoxicology Concepts and Applications (Advances In Trace Substances Research Ser. #2)
by Michael C. Newman Alan W. McIntoshThis book provides an in-depth discussion of various aspects of metal ecotoxicology. State-of-the-art information and techniques in areas ranging from metal behavior in surface waters to bioaccumulation kinetics and toxicokinetics to community effects are presented in a hierarchical arrangement. Specific topics discussed include metals in abiotic components of ecosystems, autecology (effects of metals relative to the individual or a single species), and metals in marine and freshwater systems in the context of synecology (species associated and interacting as a unit). This is an important book that will be useful to researchers, risk assessment consultants, regulatory personnel, and teachers and students.
Metal Forming
by William F. Hosford Robert M. CaddellThis book helps the engineer understand the principles of metal forming and analyze forming problems - both the mechanics of forming processes and how the properties of metals interact with the processes. In this fourth edition, an entire chapter has been devoted to forming limit diagrams and various aspects of stamping and another on other sheet forming operations. Sheet testing is covered in a separate chapter. Coverage of sheet metal properties has been expanded. Interesting end-of-chapter notes have been added throughout, as well as references. More than 200 end-of-chapter problems are also included.
Metal Forming Processes: Developments in Experimental and Numerical Approaches
by Anupam Agrawal Kakandikar Ganesh Marotrao D. Ravi KumarMetal forming processes include bulk forming and sheet metal forming with numerous applications. This book covers some of the latest developments aspects of these processes such as numerical simulations to achieve optimum combinations and to get insight into process capability. Implementation of new technologies to improve performance based on Computer Numerical Control (CNC) technologies are also discussed, including the use of CAD/CAM/CAE techniques to enhance precision in manufacturing. Applications of AI/ML, the Internet of Things (IoT), and the role of tribological aspects in green engineering are included to suit Industry 4.0. Features: • Covers latest developments in various sheet metal forming processes • Discusses improvements in numerical simulation with various material models • Proposes improvements by optimum combination of process parameters • Includes finite element simulation of processes and formability • Presents a review on techniques to produce ultra-fine-grained materials This book is aimed at graduate students, engineers, and researchers in sheet metal forming, materials processing and their applications, finite element analysis, manufacturing, and production engineering.
Metal Free C-H Functionalization of Aromatics
by Valery Charushin Oleg ChupakhinThe series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
Metal Ions In Biological Systems, Volume 44: Biogeochemistry, Availability, and Transport of Metals in the Environment
by Helmut Sigel Roland SigelVolume 44, devoted solely to the vital research areas concerning the biogeochemistry of metals and their transport in the environment and availability to living systems, offers 9 timely and authoritative chapters on these fascinating topics by 19 internationally recognized experts.
Metal Ions in Biochemistry: 2nd Edition
by Pabitra Krishna Bhattacharya Prakash B. SamnaniThe second edition of Metal Ions in Biochemistry deals with the multidisciplinary subject of bio-inorganic chemistry, encompassing the disciplines of inorganic chemistry, biochemistry and medicine. The book deals with the role of metal ions in biochemistry, emphasising that biochemistry is mainly the chemistry of metal-biochemical complexes. Hence, the book starts with the structures of biochemicals and the identification of their metal binding sites. Thermodynamic and kinetic properties of the complexes are explained from the point of view of the nature of metal-ligand bonds. Various catalytic and structural roles of metal ions in biochemicals are discussed in detail. Features The role of Na+ and K+ in brain chemistry. The role of zinc insulin in glucose metabolism and its enhancement by vanadium and chromium compounds. Discussion of the role of zinc signals, zinc fingers and cascade effect in biochemistry. Haemoglobin synthesis and the role of vitamin B12 in it. The role of lanthanides in biochemical systems. A detailed discussion of the role of non-metals in biochemistry, a topic missing in most of the books on bio-inorganic chemistry. The study of bio-inorganic chemistry makes biochemists rethink the mechanistic pathways of biochemical reactions mediated by metal ions. There is a realisation of the role of metal complexes and inorganic ions as therapeutics such as iron in leukaemia, thalassemia and sickle cell anaemia, iodine in hypothyroidism and zinc, vanadium and chromium in glucose metabolism. The most recent realisation is of the use of zinc in the prevention and treatment of COVID-19.
Metal Ions in Biological Systems, Volume 43 - Biogeochemical Cycles of Elements: Volume 29: Biological Properties Of Metal Alkyl Derivatives (Metal Ions In Biological Systems Ser. #29)
by Astrid Sigel; Helmut SigelMetal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemis
Metal Ions in Biological Systems: Volume 14: Inorganic Drugs in Deficiency and Disease
by Astrid Sigel Helmut SigelThis book describes drug metal-ion interactions in the gut and deals with the deficiency of zinc and iron and their pharmacological use. It covers anti-inflammatory activities of copper and gold complexes and considers the role of metal ions and chelating agents in anti-viral chemotherapy.
Metal Ions in Biological Systems: Volume 15: Zinc and its Role in Biology and Nutrition (Metal Ions In Biological Systems Ser. #24)
by Helmut SigelThis volume first considers the categories of zinc metalloenzymes, together with models of the enzymic metal-ion binding sites. It covers the nutritional aspects of zinc: its absorption and excretion, its influence on the activity of enzymes and hormones, and the zinc deficiency syndrome.
Metal Ions in Biological Systems: Volume 17: Calcium and its Role in Biology (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis book is wholly devoted to Ca2+ metal ion, as it is so important in regulating a wide variety of biological activities. It deals with calcium and brain proteins, the role of ca2+ in exocytosis, blood coagulation, and the regulation of the skeletal muscle contraction-relaxation cycle.
Metal Ions in Biological Systems: Volume 19: Antibiotics and Their Complexes (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis volume is an attempt to improve the understanding of the coordination chemistry and action of the biologically important compounds, also termed antibiotics, and to stimulate further research in this area, describing the properties of the biologically important compounds.