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Metal Ions in Biological Systems, Volume 43 - Biogeochemical Cycles of Elements: Volume 29: Biological Properties Of Metal Alkyl Derivatives (Metal Ions In Biological Systems Ser. #29)
by Astrid Sigel; Helmut SigelMetal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemis
Metal Ions in Biological Systems: Volume 14: Inorganic Drugs in Deficiency and Disease
by Astrid Sigel Helmut SigelThis book describes drug metal-ion interactions in the gut and deals with the deficiency of zinc and iron and their pharmacological use. It covers anti-inflammatory activities of copper and gold complexes and considers the role of metal ions and chelating agents in anti-viral chemotherapy.
Metal Ions in Biological Systems: Volume 15: Zinc and its Role in Biology and Nutrition (Metal Ions In Biological Systems Ser. #24)
by Helmut SigelThis volume first considers the categories of zinc metalloenzymes, together with models of the enzymic metal-ion binding sites. It covers the nutritional aspects of zinc: its absorption and excretion, its influence on the activity of enzymes and hormones, and the zinc deficiency syndrome.
Metal Ions in Biological Systems: Volume 17: Calcium and its Role in Biology (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis book is wholly devoted to Ca2+ metal ion, as it is so important in regulating a wide variety of biological activities. It deals with calcium and brain proteins, the role of ca2+ in exocytosis, blood coagulation, and the regulation of the skeletal muscle contraction-relaxation cycle.
Metal Ions in Biological Systems: Volume 19: Antibiotics and Their Complexes (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis volume is an attempt to improve the understanding of the coordination chemistry and action of the biologically important compounds, also termed antibiotics, and to stimulate further research in this area, describing the properties of the biologically important compounds.
Metal Ions in Biological Systems: Volume 21: Applications of Magnetic Resonance to Paramagnetic Species (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis book facilitates a wider use of nuclear magnetic resonance in studies of paramagnetic species. It summarizes studies of magnetically coupled metalloproteins, of paramagnetic heme proteins, and of metal-porphyrin-induced dipolar shifts for conformational analysis.
Metal Ions in Biological Systems: Volume 22: Endor: EPR, and Electron Spin Echo for Probing Coordination Spheres (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis volume focuses on the physical methods to probe the coordination sphere of metal ions in biological systems, which are based on para-magnetic species, namely, the electron nuclear double resonance (ENDOR), electron paramagnetic resonance (EPR), and electron spin echo (ESE) techniques.
Metal Ions in Biological Systems: Volume 23: Nickel and its Role in Biology (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis book considers nickel in the environment and in aquatic systems and outlines its role for plants. It discusses the toxicology of nickel compounds and the role of nickel in carcinogenesis, focusing on the analysis of nickel in biological materials and the related difficulties.
Metal Ions in Biological Systems: Volume 28: Degradation of Environmental Pollutants by Microorganisms and Their Metalloenzymes (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelContinuing to explore the relationship between the chemistry of metals and life processes, this volume in the Metal Ions in Biological Systems series examines the degradation of environmental pollutants by micro-organisms. It covers the action of micro-organisms and metalloenzymes on lignin, tannins, hemicelluloses, cellulose and aromatic compounds, as well as on halogenated aromatics and aliphatics; analyzes mechanistic aspects; considers the role of metalloproteases in biotechnology and wastewater sludge treatment; and describes the metal-dependent conversion of inorganic nitrogen and sulfur compounds.
Metal Ions in Biological Systems: Volume 29: Biological Properties of Metal Alkyl Derivatives (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis volume is devoted to the research area regarding the biological properties of metal alkyl derivatives, offering an authoritative account of this subject by 16 scientists. In 11 chapters, Biological Properties of Metal Alkyl Derivatives highlights, in detail, derivatives of germanium, tin, lead, arsenic, antimony, selenium, tellurium, cobalt (vitamin B12 derivatives) and nickel (coenzyme F430), including the role of (mainly) micro-organisms in their formation. The derivatives of indium, thallium, bismuth, various transition metals and mercury are also covered to some extent, as are those of the non-metals silicon, phosphorus and sulfur, and the haloperoxidase route of the biogenesis of halomethanes by fungi and plants. The properties of these alkyl derivatives, their biosynthesis, including mechanistic aspects, their appearance in waters (rivers, lakes, oceans) and sediments, and their physiological and toxic effects are summarized.
Metal Ions in Biological Systems: Volume 30: Metalloenzymes Involving Amino Acid-residue and Related Radicals (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelThis volume is devoted solely to the research area of metalloenzymes involving amino acid-residue and related radicals. Topics covered include: general considerations; structure, function and engineering of peroxidases; and ribonucleotide reductase in mammalian systems.
Metal Ions in Biological Systems: Volume 36: Interrelations Between Free Radicals and Metal Ions in Life Processes (Metal Ions In Biological Systems Ser. #28)
by Astrid Sigel Helmut SigelContinues the tradition of excellence established in previous volumes in this acclaimed series. Volume 36 focuses on the vibrant research area concerning the interrelation between free radicals and metal ions and their resulting effects on life processes; it offers an authoritative and timely account of this fascinating area of research in 21 chapters.
Metal Ions in Biological Systems: Volume 37: Manganese and Its Role in Biological Processes (Metal Ions in Biological Systems)
by Helmut Sigel"Highlights the availability of magnesium to organisms, its uptake and transport in microorganisms and plants as well as its role in health and disease of animals and humans including its toxicology."
Metal Ions in Biological Systems: Volume 38: Probing of Proteins by Metal Ions and Their Low-Molecular-Weight Complexes (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelVolume 38: Probing of Proteins by Metal Ions and Their Low-Molecular-Weight Complexes focuses on the vibrant area of probing enzymes or proteins by metal ions and small complexes. It offers a summary of the basic characteristics of the amide bond, emphasizing its proton and metal ion interactions, including a quantitative analysis of its hydrolysis and formation. Topics include Peptide bonds, footprinting, protein degradation, protein complexes, and protein cross-linking.
Metal Ions in Biological Systems: Volume 40: The Lanthanides and Their Interrelations with Biosystems (Metal Ions in Biological Systems)
by Astrid Sigel Helmut SigelMany may know lanthanides under the homier name of rare earth elements, but that is less used scientifically because they are, in fact, not at all rare. Highlighting fast-moving research on lanthanides and their interrelations with biosystems, this book emphasizes the recent impact of these metals in biochemical, biological, and medical research, including in magnetic resonance imaging (MRI). The first two chapters outline their abundance and distribution, chemical properties such as oxidation states and ionic radii, and their mobilization through microorganisms like bacteria and fungi. It is written by 38 internationally recognized experts and enriched with nearly 200 illustrations and 1900 references.
Metal Ions in Biological Systems: Volume 41: Metal Ions and Their Complexes in Medication (Metal Ions in Biological Systems #Vol. 41)
by Patrick Graupp Robert J. WronaMetal ions are currently used for such applications as diabetes, anti-inflammatory, rheumatoid arthritis, psychiatric, and anti-ulcer medications, using compounds of vanadium, copper and zinc, gold, lithium, and bismuth, respectively. This text explores these applications in addition to an assessment of chelation therapy, uses in environmental scie
Metal Ions in Biological Systems: Volume 42: Metal Complexes in Tumor Diagnosis and as Anticancer Agents (Metal Ions In Biological Systems Ser. #28)
by Astrid Sigel Helmut SigelOffering an authoritative and timely account by twenty-nine internationally recognized experts, Metal Ions in Biological Systems: Metal Complexes in Tumor Diagnosis and as Anticancer Agents is devoted solely to the vital research area concerning metal complexes in cancer diagnosis and therapy. In fourteen stimulating chapters, the book focuses on d
Metal Ions in Biological Systems: Volume 9: Amino Acids and Derivatives as Ambivalent Ligands (Metal Ions in Biological Systems)
by Helmut SigelThis book focuses on the connection between the chemistry of metal ions and their role for life, and covers complexes with a number of amino acids with chelatable side chain donor atoms. It discusses metal ion-protein interactions and the ligating ambivalency of nucleotides.
Metal Ions in Biology
by A. K. Tyagi Adish Tyagi Rohit Singh ChauhanThis book discusses the inherent need for and significance of metal ions in metabolic reactions. It details their essential elements and mechanistic prospects in regulating biological reactions, as well as covers the broad domain of elements, including main group as well as transition elements, in a comparative and comprehensive manner. Contemporary and advanced topics, such as nuclear medicine and biomineralization, are also covered.Features: Highlights the different behaviors of Fe/Cu proteins and the structural changes during their biological functioning. Discusses the mechanistic prospects of various enzymes and proteins, e.g., Cu‑Zn SOD, zinc finger, and ionophores. Explores the chemical and biological prospects of trace and ultra‑trace elements. Includes biomimetic models of iron and copper. Reviews the criteria for nature selecting metal ions, why only certain elements are essential, and the differences between biologically induced and biologically controlled biomineralization. This book is aimed at graduate students and researchers in chemical engineering, materials science, chemistry, and biological sciences.
Metal Ions in Fungi
by Günther WinkelmannPresents the latest advances in the study of the intracellular fate and transport of metal ions in fungi, emphasizing the mechanisms that regulate cellular concentration. The book explains the expanding relationship between molecular genetics and inorganic biochemistry.
Metal Ions in Neurological Systems
by Henryk Kozlowski Wolfgang LinertMetal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.
Metal Matrix Composites
by C.T. LynchThe concept of reinforcing a material by the use of a fiber is not a new one. The Egyptian brick layer employed the same principle more than three thousand years ago when straw was incorporated into the bricks. More recent examples of fiber reinforced composites are steel-reinforced concrete, nylon and rayon cord reinforced tires, and fiberglass reinforced plastics. In the last several years considerable progress has been made on new composite structures particularly utilizing boron (on tungsten substrate) fibers in various matrices. Many of these advances have been reviewed recently by P. M. Sinclair1 and by Alexander, Shaver, and Withers.2 An excellent earlier survey is available by Rauch Sutton, and McCreight.3 Boron-reinforced epoxy composites are being fabricated and tested as jet engine components, fuselage components, and even as a complete aircraft wing because of the tremendous gain in experimentally demonstrated properties such as modulus, strength, and fatigue resistance, particularly on a weight normalized (e.g., strength/density) basis. Other than glass/epoxy and boron/ epoxy composites and perhaps boron/aluminum, the systems now under study are in the early stages of research and development. These include other boron/metal composites, graphite/polymer, graphite/metal, graphite/graphite, alumina/metal, and aligned eutectic (directionally, solidified) combinations. As Sinclair points out, designers are wary about filamentary composites becausethere is little background information and scant experience.
Metal Micro-Droplet Based 3D Printing Technology
by Jun Luo Lehua Qi He Shen Hongcheng LianThis book introduces a unique 3D printing method that prints metal parts by ejecting metal micro-droplets: a low-cost, contactless, and environmentally friendly 3D printing technology. This book follows a deductive approach to describe the fundamentals of metal droplet-based 3D printing and reveal the relationships and unique features among multiple specific techniques used in droplet-based 3D printing. It starts with a general description of the principles and techniques involved in this technology and then focuses on the details of several specific metal droplet-ejection methods. Next, it puts forward various specific 3D printing techniques and illustrates their applications. This book is a valuable reference for scholars and researchers who work on metal 3D printing and other related areas. It is also used as a textbook for college graduate courses in mechanical manufacturing and material processing.
Metal Nanocomposites in Nanotherapeutics for Oxidative Stress-Induced Metabolic Disorders (Emerging Materials and Technologies)
by Anindita BeheraThis book highlights the role and mechanism of different metal nanocomposites toward oxidative stress-induced metabolic disorders including metabolic pathways affected by oxidative stress and related pathophysiology. The book includes an illustrative discussion about the methods of synthesis, characterization, and biomedical applications of metal nanocomposites. It focuses on the therapeutic approaches for metabolic disorders due to oxidative stress by nano delivery systems. Moreover, the book includes chapters on nanotherapeutic approaches toward different diseases, including diabetes mellitus, obesity, cardiovascular disorders, cancers, and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. This book is aimed at researchers and graduate students in nanocomposites, nano delivery systems, and bioengineering. Features Discusses nanocomposites in the field of therapy for diabetes, obesity, cardiovascular disorders, neurodegenerative diseases, and cancers Details the pathophysiology of oxidative stress-induced metabolic disorder Explains mechanisms of the antioxidant potential of metal nanocomposites Discusses pathways to elucidate the therapeutic activity Reviews specific and precise applications of metal nanocomposites against lifestyle-induced disorders
Metal Nanoparticles in Microbiology
by Mahendra Rai Nelson DuranFollowing an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.