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Mit Quanten rechnen: Quantencomputer für Neugierige (essentials)
by Beatrice Marie EllerhoffDieses essential schafft lebendig und anschaulich ein Verständnis für die Vorgänge in Quantencomputern. Es geht den Quantenphänomenen der Verschränkung und Überlagerung sowie der Frage, wie sie zum Rechnen verwendet werden können, auf den Grund. Gezeigt werden die Kodierung von Information, die Erklärung einfacher Algorithmen und die mögliche Anwendung. Ein Glossar am Ende des essentials erklärt die wichtigsten Begriffe.
Mit der Stringtheorie zum Urknall: Eine Reise an den Ursprung des Universums (essentials)
by Jan LouisDie Geschichte des Universums fasziniert seit jeher den Menschen. Durch das Zusammenspiel von Kosmologie, Allgemeiner Relativitätstheorie, Teilchenphysik und Quantentheorie gelingt es heute, sie physikalisch zu rekonstruieren. Nur der Anfang, der Urknall, entzieht sich bisher den gesicherten Gesetzen der Physik. Je mehr man sich ihm nähert, umso spekulativer wird die Geschichte. Mit diesem Buch wird der Leser auf eine Reise zum Urknall eingeladen und unterwegs lernt er die verschiedenen, zum Verständnis notwendigen, physikalischen Entdeckungen kennen. Dabei wird auch die Stringtheorie als eine mögliche allumfassende physikalische Theorie vorgestellt, die das Potenzial hat, den Urknall zu erklären. Ihre zum Teil spektakulären Vorhersagen, wie z.B. zusätzliche Raumdimensionen oder Paralleluniversen, werden prägnant erläutert.
Mit einfacher Sprache Wissenschaft kommunizieren (essentials)
by Andreas BaumertSchreiben für den fachfremden, gut ausgebildeten Leser: Worauf muss ein Autor achten? Was geschieht, wenn jemand einen Text versteht, wie kann man ihn dabei unterstützen? Was ist einfache Sprache in Wissenschaft und Technik? Wer eine Vorstellung vom Leser hat, kann auch für diesen schreiben. Mit einfacher Sprache, korrektem und stilistisch hochwertigem Deutsch unterstützt der Schreiber die Prozesse im Gehirn des Lesers. Dieses essential sieht das Arbeitsgedächtnis und seine Anbindung an das Langzeitgedächtnis als entscheidend für das Verstehen. Dessen Aufgaben können Autoren unterstützen und dem Leser so die Lektüre erleichtern. Einfache Sprache fällt dem Leser nur dadurch auf, dass er einen Text gut versteht. Voraussetzung ist immer, dass dieser Text für die Zielgruppe geschrieben ist, der ein Leser angehört.
Mites: Ecology, Evolution & Behaviour
by David Evans Walter Heather C. ProctorThere are over 40 000 named species of mite, and if estimates for unnamed species are included, then up to 1 million may grace the planet. By comparison, there are approximately 40 000 species of vertebrates, half of them fish, alive today. Mites are predators, parasites, herbivores and detritivores. They live in the dark depths of the ocean, in the lungs of birds, on the leaves of rainforest plants, and in human clothes and bedding. They are vectors of disease, vital players in soil formation, and important agents of biological control. Despite the grand diversity of mites, these small arthropods are often overlooked, and even trained biologists can be unaware of their significance. This books aims to fill the gap in our understanding of these intriguing creatures. It surveys life cycles, feeding behaviour, reproductive biology and host-associations of mites, without requiring prior knowledge of their morphology or taxonomy. The text is richly illustrated with line drawings and photographs. Topics covered include evolution of mites and other arachnids, mites in soil and water, mites on plants and animals, sperm transfer and reproduction, and mites as models of ecological and evolutionary theories.
Mitigating Environmental Stresses for Agricultural Sustainability in Egypt (Springer Water)
by Mohamed Abu-Hashim Hassan Awaad Abdelazim NegmThis book focuses on the soil and environmental resources and how to utilize them under Egyptian conditions to achieve tolerance to environmental abiotic stresses, i.e., drought, heat, salt, pollutants, and biotic stresses such as disease resistance. Further, it explores ways to increase productivity, improve the quality of field crops, and reduce the food gap. The application of modern technologies is an essential mechanism for improving crops' productivity through laser, seed technology, mycorrhiza, and biotechnology to enhance the yield of genotypes in sustainable farming systems. Therefore, this book discusses fundamental ways to increase productivity under various environmental circumstances. The book reflects the enormous potential held by horizontal expansion in the newly reclaimed lands in Egypt. Tapping that potential depends on developing crops that are highly tolerant to environmental stresses and mitigating the impacts of climate changes around the world to help Egypt and countries with similar weather and water deficits achieve the 2030 sustainability agenda for agriculture. Given its profundity and scope, the book offers a valuable asset for stakeholders, policy planners, decision-makers, researchers, and scientists in Egypt and worldwide.
Mitigating Shipping Emissions in European Ports: Social and Environmental Benefits (SpringerBriefs in Applied Sciences and Technology)
by Constantin Zopounidis Alexandra Maragkogianni Spiros PapaefthimiouThe book quantifies the impact of in-port ships’ greenhouse gas emissions and air pollution in adjacent cities, and evaluates the feasibility of implementing shore-side electricity facilities in Europe to reduce the unwanted social and environmental effects of ships at berth. The book also discusses the potential of future “green” ports and the use of shore side electricity as a means of achieving them. Individual chapters focus on the economic and social costs of in-port ships’ emissions by illustrating current environmental policies to mitigate air emissions and the available abatement measures for in-port emissions. It also discusses the external cost of vessel emissions in ports as well as the impacts on air quality and human health. Examining the expected barriers to the implementation of shore- side electricity facilities, it proposes policies to accelerate the implementation of relevant mitigation measures.
Mitigation and Adaptation Strategies Against Climate Change in Natural Systems (Environmental Earth Sciences)
by Rajiv Kumar Srivastava Arun ChakrabortyThis book addresses strategies for mitigating and adapting to climate change in natural systems. According to the IPCC (2021) report, human-induced climate change has widespread global effects, significantly impacting natural ecosystems. Extreme weather events linked to climate change harm terrestrial, freshwater, ocean, and coastal ecosystems, reduce food security, displace populations, damage livelihoods, health, and security, and exacerbate inequality. While the impacts of climate change are vast and varied, making it impossible to cover every sector, the authors have aimed to address key areas and offer strategies for combating climate change through mitigation and adaptation. The book is structured into five sections: • Land (agriculture, horticulture, soil, forest) • Water (rivers, lakes) • Atmosphere (hydrology, climate) • Technologies/Approaches (remote sensing, GIS, AI tools, ChatGPT) • Case Studies (crops, forests, soil glomalin application, eco-friendly fertilizers), with a focus on modelling approaches to assess these strategies. Additionally, the authors reviewed related works on climate change mitigation and adaptation, identifying a gap in using newer technologies and approaches. The book also covers topics such as water quality and the analysis of several greenhouse gases such ad NO2, O3, CO2 and CH4 in the environment. This book will be beneficial for students, educators, professionals, researchers, policymakers, and farmers. It provides content ranging from introductory to advanced levels, making it accessible to those working in environmental science.
Mitigation of Landfill Gas Emissions
by Malgorzata PawlowskaLandfilling has been and still remains an important means of municipal solid waste management but it poses a threat to the purity of the environment, especially air. In the coming years, a radical decline in the share of landfilling in waste disposal practices should not be expected. However, this is not to say that people are powerless in the face
Mitochondria
by Dario Leister Johannes M. HerrmannThis book offers a broad collection of methods for studying the molecular biology, function, and features of mitochondria. In the past decade, mitochondrial research has elucidated the important influence of mitochondrial processes on integral cell processes. This practical guide presents a wide spectrum of mitochondrial methods, each written by specialists with solid experience and intended for implementation by novice and expert researchers alike.
Mitochondria
by Dejana Mokranjac Fabiana PerocchiThis volume compiles a broad range of step-by-step protocols, complementary to the ones published in the first edition of this book, to study various aspects of mitochondrial structure and function in different model organisms, both in vitro and in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mitochondria: Practical Protocols, Second Edition aims to be useful for beginners as well as for experienced researchers in the field.
Mitochondria
by Immo E. Scheffler"This volume inspires. It certainly will be much appreciated by cell biologists all over the world. " Quarterly Review of Biology, March 2009 This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria. This new edition brings readers completely up to date on the many significant findings that have occurred in the eight years since the book was first published. As in that seminal first edition, the second edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The new edition provides thorough updates of all literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-à-vis a broad range of issues in cellular and molecular biology. The book includes detailed descriptions of current and developing technologies around mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics. This book is an invaluable resource for all geneticists, biologists, and educators in life sciences. It is also of interest for advanced students in genetics and molecular biology.
Mitochondria and Cancer
by Keshav Singh Leslie CostelloThe book begins with a general overview of Warburg Hypothesis, mitochondrial structure and function, and then outline more specifically the metabolic and molecular alterations in mitochondria that are associated with human cancer and their clinical implications. An emphasis is also placed on mtDNA mutations and their potential role in carcinogenesis. The potential use of mitochondria as biomarkers for early detection of cancer, or as unique cellular targets for novel and selective anti-cancer agents will also be discussed.
Mitochondria and Cell Death
by David M. HockenberyThis volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material. Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology, as well as those interested in the study of mitochondria and cell biology.
Mitochondria and Their Role in Cardiovascular Disease
by José Marín-GarcíaOver the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in the field of mitochondrial cardiovascular medicine. The book begins with a general introduction to mitochondria, followed by laboratory methods to study the structure and function of the organelle, regulation of replication and biogenesis, and the mechanisms and functional consequences of mitophagia and mitochondrial dynamics. Subsequent chapters deal with mitochondrial oxidative stress and the role that the organelle plays in cell signaling and cell death. Discussions will be undertaken on the biochemistry of mitochondrial cell signaling, including the nature of the proteins engaged in these processes, many of them only recently discovered. Later chapters examine the role of mitochondria and mitochondrial abnormalities in cardiovascular diseases, including their diagnosis, therapeutic options currently available, animal models of mitochondrial disease, and new frontiers in mitochondria cardiovascular medicine, including areas of research that are relatively new or developing, such as proteomics, next generation sequencing, and systems biology.
Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself
by Lee Know&“From infertility to aging to cancer and neurological disease, Dr. Lee Know will teach you that mitochondria play a central role in much that we care about in health and disease.&”—Stephanie Seneff, senior research scientist, MIT and author of Toxic Legacy With information for patients and practitioners on optimizing mitochondrial function for greater health and longevityWhy do we age? Why does cancer develop? What&’s the connection between heart failure and Alzheimer&’s disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it&’s the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years.Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity.Dr. Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization and how to implement their use successfully, including:CoQ10D-RiboseCannabinoidsKetogenic dietary therapyand more!Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.&“Dr. Lee Know does a brilliant job shedding light on this once ignored organelle and shows us how to care for our most important metabolic system.&”—Dr. Nasha Winters, co-author of The Metabolic Approach to Cancer
Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy
by Dhyan ChandraThis book highlights the importance of phytochemicals and mitochondria in cancer prevention and therapy. Recent scientific discoveries have identified that naturally occurring biologically active compounds (i. e. phytochemicals) target multiple steps of tumorigenesis leading to the inhibition or delay in cancer progression. Mitochondria, organelles within a cell, are a critical target for phytochemicals in regulating the initiation, promotion, and progression of cancer. The book is divided into three parts to better communicate the important findings related to phytochemicals and mitochondria in cancer research. The first part describes updates on environmental and genetic factors causing cancer initiation and progression, the role of mitochondria function in regulating the process of tumorigenesis, and the role of mitochondria in regulating cell death such as apoptosis, autophagy, and necroptosis. The second part focuses on the elucidation of key target proteins that could be exploited for cancer prevention, an the role of phytochemicals in cancer prevention, updates on basic research related to phytochemicals action critical for cancer prevention, and updates on translational knowledge on cancer prevention by phytochemicals. The third part provides updates on phytochemicals targeting mitochondria for cancer therapy, an overview of action of phytochemicals on cancer stem cells, updates on the role of microRNA in phytochemicals-based therapy of cancer, and updates on phytochemicals-based translation research on therapy for metastatic cancer.
Mitochondria in Health and Disease
by Carolyn D. BerdanierIt was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text discusses f
Mitochondria in Health and in Sickness (Advances in Experimental Medicine and Biology #1158)
by Mohan Babu Andrea UrbaniBesides bringing together researchers and clinicians from various disciplines to share their scope of research on the seminal role of mitochondria in human disease, this original volume of the book has a broader appeal by exploring the health and disease of mitochondria, with specific emphasis on how mitochondrial dysfunction contributes to the development of various neurodegeneration, cancer, and metabolic disorders. The book also provides a foundational overview of the mitochondrial pathogenic or genetic variants and highlights various analytical tools used in the field of mitochondrial genetics; mitochondrial replacement therapy and strategies geared towards shifting heteroplasmy in individuals with mitochondrial disease; how state-of-the-art omics technologies (proteomics, functional genomics) have been employed to study mitochondrial biology in healthy and disease states; post-translational modifications in the regulation of mitochondrial proteins; and the role of mitochondria in host-pathogen interactions. Current approaches taken to study steady-state characteristics of mitochondrial structure and function in live mammalian cells in the contexts of normal and diseased states, and most recent research efforts to develop compounds with anti-cancer potential by targeting mitochondrial proteases or advances in therapeutic approaches towards mitochondrial disease were also explored. By covering this broad range of topics, our hope is to disseminate a wealth of knowledge on the critical role of mitochondria, and how to probe its function in health and in sickness.
Mitochondria in Liver Disease
by DERICK HAN NEIL KAPLOWITZ" excellent, well-organized, and timely."-Lester Packer and Enrique Cardenas, University of Southern California, Los Angeles, from the Series PrefaceThe liver is a vital organ that is responsible for a wide range of functions, most of which are essential for survival. The multitude of functions the liver performs makes it vulnerable to a wide range
Mitochondria: Methods and Protocols (Methods in Molecular Biology #2497)
by Namrata TomarThis volume details comprehensive protocols and methodologies to assess mitochondrial bioenergetics and dynamics in different tissues and cells involving health and pathological states. Chapters guide readers through methods for assessment of the energy metabolism including Oxygen Consumption Rate (OCR), mitochondrial membrane potential, and measuring mitochondrial Ca2+ handling, and ROS emission. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting, and systematic reproducible protocols. Authoritative and cutting-edge, Mitochondria: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Mitochondrial Bioenergetics
by Carlos M. Palmeira António J. MorenoIncreasing interest in mitochondrial bioenergetics is being driven by the impact of drug and environmental chemical-induced disturbances of mitochondrial function as well as hereditary deficiencies and the progressive deterioration of bioenergetic performance with age. These initiatives have fostered the investigation of genetic and environmental influences on bioenergetics. In Mitochondrial Bioenergetics: Methods and Protocols, researchers in the field detail the practical principles and assays designed to derive quantitative assessment of each set of parameters that reflect different aspects of mitochondrial bioenergetics. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls Authoritative and practical, Mitochondrial Bioenergetics: Methods and Protocols helps elevate the quality and rate of investigative discoveries regarding disease states associated with environmental or genetic influences on mitochondrial bioenergetics.
Mitochondrial Bioenergetics: Methods And Protocols (Methods in Molecular Biology #810)
by Carlos M. Palmeira António J. MorenoThis second edition volume expands on the previous edition with chapters discussing the latest developments and research initiatives in mitochondrial functions. The chapters in this book explore topics such as high-resolution fluorespirometry and OXPHOS protocols in human cells, analysis of mitochondrial oxygen consumption, mitochondrial bioenergetics, and mitochondrial dynamics in mammalian cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Mitochondrial Bioenergetics: Methods and Protocols, Second Edition is a valuable resource for students, and practitioners in the pharmaceutical sciences, environmental sciences, and mitochondrial genetics industries.
Mitochondrial Bioenergetics: Methods and Protocols (Methods in Molecular Biology #2878)
by Carlos M. Palmeira Paulo J. OliveiraThis updated volume provides a concise set of protocols on the conceptual principles and practical considerations pertinent to research in mitochondrial function. Driven by the impact of drug- and environmental chemical-induced disturbances on mitochondrial function, hereditary deficiencies, and the age-related decline in bioenergetic performance, this book explores the latest approaches developed in this field by presenting practical principles and assays for quantitative assessments of various parameters reflecting aspects of mitochondrial bioenergetics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Mitochondrial Bioenergetics: Methods and Protocols, Third Edition serves as an ideal guide for scientists endeavoring to enhance the quality of mitochondrial research.
Mitochondrial Biology and Experimental Therapeutics
by Paulo J. OliveiraThis book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.
Mitochondrial DNA
by Jeffrey A StuartSince the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In Mitochondrial DNA: Methods and Protocols, Second Edition, specialists from eight countries share their expertise, providing detailed protocols for studying many aspects of mtDNA. The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes sections, highlighting tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Mitrochondrial DNA: Methods and Protocols, Second Edition promises to aid researchers in further expanding our knowledge of this vital area of cell biology.