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5-HT2C Receptors in the Pathophysiology of CNS Disease

by Vincenzo Di Matteo Giuseppe Di Giovanni Ennio Esposito

Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors' therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson's disease, Prader-Willi Syndrome, Alzheimer's disease and epilepsy.

5 Steps to a 5 AP Biology, 2010-2011 Edition

by Mark Anestis

The effective, five-step plan to help you succeed on the AP Biology exam. Biology is one of the more popular AP tests; it is also one of the most demanding. This popular guide provides all the latest information on the course and on the test itself.

5 Steps to a 5 AP Chemistry, 2012-2013

by John Moore Richard H. Langley

A Perfect Plan for the Perfect Score. We want you to succeed on your AP* exam. That's why we've created this 5-step plan to help you study more effectively, use your preparation time wisely, and get your best score. This easy-to-follow guide offers you a complete review of your AP course, strategies to give you the edge on test day, and plenty of practice with AP-style test questions. You'll sharpen your subject knowledge, strengthen your thinking skills, and build your test-taking confidence with Full-length practice exams modeled on the real test All the terms and concepts you need to know to get your best score Your choice of three customized study schedules--so you can pick the one that meets your needs The 5-Step Plan helps you get the most out of your study time: Step 1: Set Up Your Study Program Step 2: Determine Your Readiness Step 3: Develop the Strategies Step 4: Review the Knowledge Step 5: Build Your Confidence Topics include:Listening Comprehension; Reading Comprehension: Longer Passages; Paragraph Completion with Root Words; Paragraph Completion without Root Words; Informal Writing (Interpersonal); Formal Writing / Integrated Skills (Presentational); Informal Speaking--Simulated Conversation (Interpersonal); and Formal Oral Presentation / Integrated Skills (Presentational) Also includes: An MP3 disk and practice exams *AP, Advanced Placement Program, and College Board are registered trademarks of the College Entrance Examination Board, which was not involved in the production of, and does not endorse, this product.

5 Steps to a 5 AP Environmental Science, 2010-2011 Edition

by Linda Williams

The effective, five-step plan to help you succeed on the AP Environmental Science exam - This new addition to the 5 Steps to a 5 series covers the latest AP Environmental Science syllabus and provides model tests that reflect the latest version of the exam.

50 and More Essential NMR Experiments

by Stefan Berger Matthias Findeisen

This book is the perfect link for learning how to perform the experiments after only having studied theory. In eight chapters more than 50 essential NMR experiments are described in detail. Special focus is put on the organic set of NMR spectra (1H, 13C-APT, COSY, NOESY, HSQC and HMBC). Different chapters deal with advanced organic NMR, selective methods, heteronuclear NMR, relaxation and diffusion measurements, organic applications and maintenance. Every experiment has a section providing the reader with the purpose and scope of the specific experiment. Every experiment is concluded with the spectrum as it is obtained under the conditions described. Questionsand comments enable the reader to check their understanding. The authors are very experienced and the whole book is in full color, which enhances the reading experience and makes the spectra and other figures easier to understand.This book is strongly recommended for all students and researchers who are involved in the structural elucidation of chemical compounds both in practical education and in pursuing research, in particular if they handle an NMR spectrometer.

50 Biology Ideas You Really Need to Know

by Jv Chamary

50 Biology Ideas You Really Need to Know is your guide to the most significant and stimulating questions in the study of life. Why do species evolve? Can characteristics be inherited without DNA? Are all organisms made of cells? What makes us human? This book provides succinct answers to all these questions, and many more, in 50 lucid and engaging essays that cover both classic experiments and the latest research.From the mysteries of sex and sleep, from mass extinction to immunity, 50 Biology Ideas You Really Need to Know will open your eyes to the fundamental processes that are vital to life on Earth, including how genes control the growth and behaviour of living things, how a body develops from a single cell, and how environmental forces create natural diversity through evolution. Featuring key concepts explained in simple terms, and with clear diagrams and timelines showing major scientific discoveries within their historical context, this book will give you a complete overview of a fascinating subject.Contents include: Evolution, Genes, Homeostasis, Endosymbiosis, Sex, Multicellularity, Nerves, Genetic Drift, Speciation, Convergent Evolution, Pollination, Mimicry, Laws of Inheritance, DNA, Alternative Splicing, Viruses, Epigenetics, Photosynthesis, Cancer, Differentiation, Regeneration, Morphogenesis, Memory, Sleep, Ageing, Consciousness and the Gaia Hypothesis.

50 Earth Ideas You Really Need to Know

by Martin Redfern

This latest book in Quercus's bestselling "50 Ideas" series is a wonderfully accessible overview of the only place we know of in the universe that is capable of sustaining life. Expert popular science writer Martin Redfern covers all the natural processes of the Earth: climate, ocean currents, air currents, the elements, plate tectonics, fossils, the evolution of life, volcanology, sea levels and the ultimate fate of the Earth.

50 Facts That Should Change the World (revised and updated)

by Jessica Williams

Jessica Williams revisits her classic series of snapshots of life in the twenty-first century. Revised and updated with lots of new material, this book is every bit as vital as the first edition. From the inequalities and absurdities of the so-called developed world to the vast scale of suffering wreaked by war, famine, and AIDS in developing countries, it paints a picture of incredible contrasts. This 2.0 edition again contains an eclectic selection of facts addressing a broad range of global issues, now with added emphasis on climate change, the decline in human rights and democratic freedoms around the world, the unexpected global impact of corporate growth, sports and media madness and inequality, and lots of updated facts and figures. Each is followed by a short essay explaining the story behind the fact, fleshing out the bigger problem lurking behind the numbers. Real-life stories, anecdotes, and case studies help to humanize the figures and make clear the human impact of the bald statistics. All of the facts remind us that whether we like to think of it or not, the world is interconnected and civilization is a fragile concept. Williams makes us think about some of the hard facts about our civilization and what we can do about them.

50 Future Ideas You Really Need to Know

by Richard Watson

What will the world look like in 2020, 2030 or even 2100? How will progress in scientific research affect human life in the areas of health and lifestyle, energy and the environment, politics and conflict, space exploration and even the ultimate questions of existence? This thoroughly researched and superbly written book offers an electrifying trip through the wonders--and terrors--awaiting us over the next hundred years.

50 Future Ideas You Really Need to Know

by Richard Watson

What will the world look like in 2020, 2030 or even 2100? How will progress in scientific research affect human life in the areas of health and lifestyle, energy and the environment, politics and conflict, space exploration and even the ultimate questions of existence? This thoroughly researched and superbly written book offers an electrifying trip through the wonders--and terrors--awaiting us over the next hundred years.

50 Genetics Ideas You Really Need to Know

by Mark Henderson

In recent years knowledge of our genetic code has changed our understanding of life on Earth. New genetic technologies are transforming the way we live and promise treatments for otherwise incurable diseases. But these advances are also generating controversy, particularly surrounding issues such as cloning and designer babies. In 50 Genetics Ideas, Mark Henderson distills the central ideas of genetics in a series of clear and concise essays. Beginning with the theory of evolution, and covering such topics as the genome and how nature and nurture work together, he not only illuminates the role of genes in shaping our behaviour and sexuality, but also the very latest, cutting-edge developments in gene therapy and artificial life. Accessible and informative, 50 Genetics Ideas is a timely introduction to this young and ground-breaking strand of science.

50 Genetics Ideas You Really Need to Know

by Mark Henderson

In recent years knowledge of our genetic code has changed our understanding of life on Earth. New genetic technologies are transforming the way we live and promise treatments for otherwise incurable diseases. But these advances are also generating controversy, particularly surrounding issues such as cloning and designer babies. In 50 Genetics Ideas, Mark Henderson distills the central ideas of genetics in a series of clear and concise essays. Beginning with the theory of evolution, and covering such topics as the genome and how nature and nurture work together, he not only illuminates the role of genes in shaping our behaviour and sexuality, but also the very latest, cutting-edge developments in gene therapy and artificial life. Accessible and informative, 50 Genetics Ideas is a timely introduction to this young and ground-breaking strand of science.

50 Human Brain Ideas You Really Need to Know

by Moheb Costandi

Neuroscience is one of the most fascinating and complex areas of scientific research, with new advances being made every day. In 50 Human Brain Ideas You Really Need to Know, Mo Costandi condenses all we know about the brain and how it works into series of introductions to the most important concepts. Outlining both long-standing theories - such as the function of neurons and synaptic transmission - and cutting-edge ideas - including neuroethics and brain-computer interfacing - with straightforward narrative and clear two-colour illustrations, this book is a perfect beginner's guide to the most powerful and mysterious organ in the body. The ideas explored include: The nervous impulse; Differences between the male and female brain; The root of addiction; Neurobiological basis for personality; The relationship between sleep and memory.

50 Ideas You Really Need to Know: Universe

by Joanne Baker

From dwarf planets to dark energy; and from the Big Bang to the death of stars, this book is the perfect introduction to the cutting-edge science that is shaping our understanding of our place in the Universe and that could lead to the next great discovery--the detection of life beyond Earth.

50 Ideas You Really Need to Know: Universe

by Joanne Baker

From dwarf planets to dark energy; and from the Big Bang to the death of stars, this book is the perfect introduction to the cutting-edge science that is shaping our understanding of our place in the Universe and that could lead to the next great discovery--the detection of life beyond Earth.

50 Physics Ideas You Really Need to Know

by Joanne Baker

In this, the second volume in an important new series presenting core concepts across a range of critical areas of human knowledge, author Joanne Baker unravels the complexities of 20th-century scientific theory for a general readership. From Hubble's law to the Pauli exclusion principle, and from Schrödinger's cat to Heisenberg's uncertainty principle, she explains ideas at the cutting-edge of scientific enquiry, making them comprehensible and accessible to the layperson.

50 Physics Ideas You Really Need to Know

by Joanne Baker

In this, the second volume in an important new series presenting core concepts across a range of critical areas of human knowledge, author Joanne Baker unravels the complexities of 20th-century scientific theory for a general readership. From Hubble's law to the Pauli exclusion principle, and from Schrodinger's cat to Heisenberg's uncertainty principle, she explains ideas at the cutting-edge of scientific enquiry, making them comprehensible and accessible to the layperson.

50 Simple Ways to Live a Longer Life

by Suzanne Bohan Glenn Thompson

In 2011, the first wave of the 76 million Baby Boomers will reach age 65, and one in three American adults will be senior citizens. Everyone wants to know how to live the healthiest and longest life. 50 Simple Ways to Live a Longer Life is an easy-to-comprehend resource packed with the most amazing health discoveries from the forefront of science. It leaves readers inspired to take active roles in extending their own lives and improving their own health. Each chapter contains a different way to extend your life, plus a "Making It Real" section that tells readers what they specifically can do to achieve these benefits. 50 Simple Ways to Live a Longer Life offers fresh perspectives and intriguing information, even on those frequently covered topics like exercise and diet. This book is an affordable, easy-to-assimilate book that will help people add years and vigor to their life.

550 AP Biology Practice Questions

by Princeton Review

THE PRINCETON REVIEW GETS RESULTS. Get extra preparation for an excellent AP Biology score with 550 extra practice questions and answers. This eBook edition has been formatted for on-screen viewing with cross-linked questions, answers, and explanations. Practice makes perfect--and The Princeton Review's 550 AP Biology Practice Questions gives you everything you need to work your way to the top. Inside, you'll find tips and strategies for tackling and overcoming challenging questions, plus all the practice you need to get the score you want. Practice Your Way to Perfection.* 2 full-length practice tests and 16 practice drills covering each subject type* Practice drills organized by the 4 "Big Ideas"Academic and Strategic Explanations.* Detailed walk-throughs of free-response questions to help you write a winning essay* Answer keys and detailed explanations for each drill and test question Techniques That Actually Work.* Tried-and-true strategies to avoid traps and beat the test* Essential tactics to help you work smarter, not harder

60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center

by M. Alma Rodriguez Thomas W. Burke Ronald S. Walters

This unique book provides a retrospective analysis of the changes in survival outcomes at the University of Texas, M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the center's tumor registry which makes this groundbreaking book possible. Tracking results across time, this book shows radical shifts in outcomes trends, where great progress has been made, and where there is still a long way to go, and offers a snapshot into the parallel history of developments in care. Such data is crucial to informing how patients are counseled, how treatment decisions are determined, and how prognoses are made. 60 Years of Survival Outcomes at the University of Texas, M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers. Each chapter deals with a specific disease site, discussing current management approaches and presenting key data replete with illustrative charts, graphs, and tables. With the resources available only to the practitioners at this inimitable institution, this book heralds a cornerstone moment in the study of survival outcomes and the depth of our knowledge of cancer care.

7.0 Tesla MRI Brain Atlas

by Zang-Hee Cho

Recent advances in MRI, especially those in the area of ultra high field (UHF) MRI, have attracted significant attention in the field of brain imaging for neuroscience research, as well as for clinical applications. In 7.0 Tesla MRI Brain Atlas: In Vivo Atlas with Cryomacrotome Correlation, Zang-Hee Cho and his colleagues at the Neuroscience Research Institute, Gachon University of Medicine and Science set new standards in neuro-anatomy. This unprecedented atlas presents the future of MR imaging of the brain. Taken at 7.0 Tesla, the images are of a live subject with correlating cryomacrotome photographs. Exquisitely produced in an oversized format to allow careful examination of the brain in real scale, each image is precisely annotated and detailed. The images in the Atlas reveal a wealth of details of the main stem and midbrain structures that were once thought impossible to visualize in-vivo. Ground breaking and thought provoking, 7.0 Tesla MRI Brain Atlas is sure to provide answers and inspiration for further studies, and is a valuable resource for medical libraries, neuroradiologists and neuroscientists.

The 7 Laws of Magical Thinking

by Matthew Hutson

Everyone - even the most jaded and sceptical - believes in 'magic', in the form of luck, mind over matter, the power of similarities, jinxes, and destiny. In this wonderful exploration of psychology, Matthew Hutson takes us on a fascinating tour of magical thinking in everyday life, revealing the healing power of John Lennon's piano; the reason gamblers kiss their tickets; and why admitting you have no free will staves off addiction.

The 7 Sexes

by Elof Axel Carlson Becky Phillips

Few of us know much about the biology of sex determination, but what could be more interesting than to discover how we are shaped into males and females? In this book, Elof Carlson tells the incredible story of the difficult quest to understand how the body forms girls and boys. Carlson's history takes us from antiquity to the present day to detail how each component of human reproduction and sexuality was identified and studied, how this knowledge enlarged our understanding of sex determination, and how it was employed to interpret such little understood aspects of human biology as the origin of intersex births.

747: Creating the World's First Jumbo Jet and Other Adventures from a Life in Aviation

by Jay Spenser Joe Sutter

This is the thrilling story behind "the Queen of the Skies"--the Boeing 747--as told by Joe Sutter, one of the most celebrated engineers of the twentieth century, who spearheaded its design and construction. Born in 1921 in Seattle, Sutter grew up on a hilltop overlooking the Boeing plant and flying field. It was a thrilling era of open cockpits, silk scarves, leather helmets, and goggles. After serving in World War 2, Sutter joined Boeing, then a small company, eager to build airplanes. In July 1965, he was asked to lead the large Boeing team designing the new 747. Pan Am wanted a new airliner as quickly as possible. This all-new transport had to be far bigger than anything in service or even on anybody's drawing board. To make it fly, Sutter and his team would have to push far beyond the technological boundaries of the late 1960s. Could it be done? Almost everything about the 747 would be unprecedented. Its cabin would be so wide that it would need two aisles. Its horizontal tail would be bigger than the wings of most airliners ever built. Jet engines big enough to lift it off the ground didn't yet exist. Runways at the world's airports couldn't handle it, and neither could Boeing's factories. They had to erect the world's largest building just to produce it. A truly mammoth undertaking, the 747 became one of the most successful airplane models ever. Sutter's vivid narrative takes us back to a time when American technology was cutting-edge--the 747, came on the market the same year that men first set foot on the moon--and jet travel was still glamorous and new. With wit and warmth, he gives an insider's sense of the larger-than-life-size personalities and the tensions in the aeronautical world. Ultimately, 747 is an inspiring story of grit and glory.

The 80/20 Principle and 92 Other Powerful Laws of Nature

by Richard Koch

In this follow-up to his best-selling The 80/20 Principle, the power law that helped hundreds of thousands achieve more by doing less, Richard Koch puts science to work, applying ninety-two other natural laws to promote the "science of success" within the ever-changing world of business. What does Charles Darwin's theory of natural selection prove about developing a niche product line? How can Isaac Newton's laws of motion and gravity help in a crowded marketplace? This is a must-have book for business leaders looking for clear, evidence-based reasoning that explains why some companies seem to find success everywhere they turn, while others don't make progress.

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