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Nrf2 and its Modulation in Inflammation (Progress in Inflammation Research #85)
by Huai DengNrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation, respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors.
Nuclear Astrophysics: A Course of Lectures
by Md A. KhanIn this volume the physics involved in various astrophysical processes like the synthesis of light and heavier elements, explosive burning processes, core collapse supernova etc have been critically addressed with minimum mathematical derivations so as to suit all faculties of the readers. For graduate students there are solved problems with exercises at the end of each chapter, for researchers some recent works on the calculation of physical parameters of astrophysical importance like the calculation of Sfactors at low energies have been included, and for amateur readers there are lot of history, information and discussion on the astronuclear phenomenon.
Nuclear Batteries and Radioisotopes
by Mark Prelas Matthew Boraas Fernando De La Torre Aguilar John-David Seelig Modeste Tchakoua Tchouaso Denis WisniewskiThis book explains the physics of nuclear battery operation. It provides a comprehensive background that allows readers to understand all past and future developments in the field. The supply and cost of radioisotopes for use in applications (focused on nuclear batteries) are covered in the initial sections of the text. The interaction of ionizing radiation with matter is discussed as applied to nuclear batteries. The physics of interfacing the radioisotopes to the transducers which represent the energy conversion mechanism for nuclear batteries are described for possible nuclear battery configurations. Last but not least the efficiencies of nuclear battery configurations are discussed combined with a review of the literature on nuclear battery research.
Nuclear Bodies and Noncoding RNAs
by Shinichi Nakagawa Tetsuro HiroseThis volume focuses on cytological, biochemical, and molecular biological methods to identify and examine the function of each nuclear body, with an emphasis on the analysis of long non-coding RNAs. Chapters focus on exploring recent studies that reveal how certain long non protein-coding RNAs accumulate in specific nuclear bodies and regulate the function of the bodies by serving as architectural components or controlling the dynamics of associating protein components. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Nuclear Bodies and Noncoding RNAs: Methods and Protocols serves as a guideline for further study into the sophisticated regulation of gene expression.
Nuclear Bodies: The Global Hibakusha
by Robert A. JacobsThe Cold War reconsidered as a limited nuclear war &“Inexorable clarity and care for his fellow humans mark Robert Jacobs's guide to the Cold War as a limited nuclear war, whose harms disfigure any possible future.&”—Norma Field, author of In the Realm of a Dying Emperor: Japan at Century&’s End In the fall of 1961, President Kennedy somberly warned Americans about deadly radioactive fallout clouds extending hundreds of miles from H‑bomb detonations, yet he approved ninety‑six US nuclear weapon tests for 1962. Cold War nuclear testing, production, and disasters like Chernobyl and Fukushima have exposed millions to dangerous radioactive particles; these millions are the global hibakusha. Many communities continue to be plagued with dire legacies and ongoing risks: sickness and early mortality, forced displacement, uncertainty and anxiety, dislocation from ancestors and traditional lifestyles, and contamination of food sources and ecosystems. Robert A. Jacobs re‑envisions the history of the Cold War as a slow nuclear war, fought on remote battlegrounds against populations powerless to prevent the contamination of their lands and bodies. His comprehensive account necessitates a profound rethinking of the meaning, costs, and legacies of our embrace of nuclear weapons and technologies.
Nuclear Chemistry: Detection And Analysis Of Radiation
by Maheshwar Sharon Madhuri SharonThis book is designed to serve as a textbook for core courses offered to postgraduate students enrolled in chemistry. This book can also be used as a core or supplementary text for nuclear chemistry courses offered to students of chemical engineering. The book covers various topics of nuclear chemistry like Shell model, fission/fusion reaction, natural radioactive equilibrium series, nuclear reactions carried by various types of accelerators. In addition, it describes the law of decay of radioactivity, type of decay, and interaction of radiation with matter. It explains the difference between ionization counter, scintillation counter and solid state detector. This book also consists of end-of-book problems to help readers aid self-learning. The detailed coverage and pedagogical tools make this an ideal textbook for postgraduate students and researchers enrolled in various chemistry and engineering courses. This book will also be beneficial for industry professionals in the allied fields.
Nuclear Choices for the Twenty-First Century: A Citizen's Guide
by Richard Wolfson Ferenc Dalnoki-VeressAn authoritative and unbiased guide to nuclear technology and the controversies that surround it.Are you for nuclear power or against it? What's the basis of your opinion? Did you know a CT scan gives you some 2 millisieverts of radiation? Do you know how much a millisievert is? Does irradiation make foods safer or less safe? What is the point of a bilateral Russia-US nuclear weapons treaty in a multipolar world? These are nuclear questions that call for nuclear choices, and this book equips citizens to make these choices informed ones. It explains, clearly and accessibly, the basics of nuclear technology and describes the controversies surrounding its use.
Nuclear Decommissioning: Planning, Execution And International Experience (Woodhead Publishing Series In Energy Ser.)
by Michele LaraiaThis book discusses the history of nuclear decommissioning as a science and industry. It explores the early, little-known period when the term “decommissioning” was not used in the nuclear context and the end-of-life operations of a nuclear facility were a low priority. It then describes the subsequent period when decommissioning was recognized as a separate phase of the nuclear lifecycle, before bringing readers up to date with today’s state of the art.The author addresses decommissioning as a mature industry in an era in which large, commercial nuclear reactors and other fuel-cycle installations have been fully dismantled, and their sites returned to other uses. The book also looks at the birth, growth and maturity of decommissioning, focusing on how new issues emerged, how these were gradually addressed, and the lessons learned from them. Further, it examines the technologies and management advances in science and industry that followed these solutions. Nuclear Decommissioning is a point of reference for industry researchers and decommissioning practitioners looking to enrich their knowledge of decommissioning in recent decades as well as the modern industry. The book is also of interest to historians and students who wish to learn more about the history of nuclear decommissioning.
Nuclear Dynamics in the Nucleonic Regime (Series in Fundamental and Applied Nuclear Physics)
by D Durand E Suraud B TamainOver the last decade one of the most active areas of research in nuclear physics has been the study of systems of nucleons in various dynamical situations. Heavy-ion collisions at beam energies in the range 30-150 MeV per nucleon, where subnucleaonic degrees of freedom can be considered as frozen, allow such systems to be studied in detail. Nuclear
Nuclear Electric Power
by J. Brian KnowlesAssesses the engineering of renewable sources for commercial power generation and discusses the safety, operation, and control aspects of nuclear electric powerFrom an expert who advised the European Commission and UK government in the aftermath of Three Mile Island and Chernobyl comes a book that contains experienced engineering assessments of the options for replacing the existing, aged, fossil-fired power stations with renewable, gas-fired, or nuclear plants.From geothermal, solar, and wind to tidal and hydro generation, Nuclear Electric Power: Safety, Operation, and Control Aspects assesses the engineering of renewable sources for commercial power generation and discusses the important aspects of the design, operation, and safety of nuclear stations.Nuclear Electric Power offers:Novel, practical engineering assessments for geothermal, hydro, solar, tidal, and wind generation in terms of the available data on cost, safety, environmental damage, capacity factor reliability, and grid compatibility, with some nuclear comparisonsEigenvalues and real frequency response functions to assess the stabilities of reactor power, two-phase channel flow, and a Grid networkA non-linear control strategy with simulation results for a Design Base Accident scenarioOriginal analyses with experimental validation of molten fuel coolant interactions and aircraft impacts on rigid structuresAnalysis of the circumstances that led to the Fukushima disasterNuclear Electric Power is an important book for all international nuclear power agencies and those who work within the field.
Nuclear Electronics with Quantum Cryogenic Detectors
by Vladimir PolushkinNUCLEAR ELECTRONICS WITH QUANTUM CRYOGENIC DETECTORS An ideal, comprehensive reference on quantum cryogenic detector instrumentation for the semiconductor and nuclear electronics industries Quantum nuclear electronics is an important scientific and technological field that overviews the development of the most advanced analytical instrumentation. This instrumentation covers a broad range of applications such as astrophysics, fundamental nuclear research facilities, chemical nano-spectroscopy laboratories, remote sensing, security systems, forensic investigations, and more. In the years since the first edition of this popular resource, the discipline has developed from demonstrating the unprecedented energy resolving power of individual devices to building large frame cameras with hundreds of thousands of pixel arrays capable of measuring and processing massive information flow. Building upon its first edition, the second edition of Nuclear Electronics with Quantum Cryogenic Detectors reflects the latest advances by focusing on novel microwave kinetic inductance detection devices (MKIDs), the microwave superconducting quantum interferometers (MSQUIDs) extending by orders of magnitude the scalability of cryogenic detectors implementing newly developed multiplexing techniques and decoding algorithms. More, it reflects on the interaction of quantum cryogenic detectors—which in turn can be paired with semiconductor large frame cameras to provide a broad picture of a sky or chemical sample—and quantum devices, making this second edition of Nuclear Electronics a one-stop reference for the combined technologies. The book also provides an overview of latest developments in front-end electronics, signal processing channels, and cryogenics—all components of quantum spectroscopic systems—and provides guidance on the design and applications of the future quantum cryogenic ultra-high-resolution spectrometers. Nuclear Electronics with Quantum Cryogenic Detectors readers will also find: Fully revised material from the first edition relating to cryogenic requirements Brand new chapters on semiconductor radiation sensors, cooling and magnetic shielding for cryogenic detector systems; front-end readout electronic circuits for quantum cryogenic detectors; energy resolution of quantum cryogenic spectrometers; and applications of spectrometers based on cryogenic detectors A number of brand-new chapters dedicated to applications using MSQUID multiplexing technique, an area that will dominate the cryogenic detector field in the next decades Nuclear Electronics with Quantum Cryogenic Detectors provides a comprehensive overview of the entire discipline for researchers, industrial engineers, and graduate students involved in the development of high-precision nuclear measurements, nuclear analytical instrumentation, and advanced superconductor primary sensors. It is also a helpful resource for electrical and electronic engineers and physicists in the nuclear industry, as well as specialist researchers or professionals working in cryogenics applications like biomagnetism, quantum computing, gravitation measurement, and more.
Nuclear Endocrinology
by Doina PiciuNuclear medicine is an important element of daily practice for the endocrinologist, both for diagnosis and for treatment. The continuous rapid development of nuclear medicine procedures has created the need for a concise, up-to-date practical guide that presents the essential information required by the endocrinologist. This book is designed to ensure ease of use in clinical practice and provides the most relevant information on nuclear medicine as applied to endocrine pathology. It is divided into three sections covering general aspects of nuclear medicine, the role of nuclear endocrinology in diagnosis, and the role of nuclear endocrinology in therapy. The endocrine glands are covered by organ and by pathology. Pertinent background information is provided, choice of radiopharmaceutical is explained, and the role of different image acquisition techniques is discussed. In addition, informative clinical cases are presented with the aid of high-quality images.
Nuclear Energy
by Nicholas TsoulfanidisNuclear Energy provides an authoritative reference on all aspects of the nuclear industry from fundamental reactor physics calculations to reactor design, nuclear fuel resources, nuclear fuel cycle, radiation detection and protection, and nuclear power economics. Featuring 19 peer-reviewed entries by recognized authorities in the field, this book provides comprehensive, streamlined coverage of fundamentals, current areas of research, and goals for the future. The chapters will appeal to undergraduate and graduate students, researchers, and energy industry experts.
Nuclear Energy: An Answer to Climate Change?
by James Weber Michael W. Toffel Glen W. S. DowellEnvironmental activist groups have traditionally opposed nuclear energy. However, the growing environmental problems associated with global climate change require major changes to reduce the carbon intensity of electricity generation. Should environmental groups reverse course and support the construction of new nuclear plants—using technology that could be rapidly deployed at scale—to reduce greenhouse gas emissions that are causing global climate change?
Nuclear Energy: Power From the Atom
by Troon Harrison AdamsBecause of global warming, nuclear energy is getting a second look. This important book discusses the benefits and drawbacks of this controversial, but clean and reliable, source of power. Case studies show how new technologies are helping make production of nuclear energy safer.
Nuclear Energy: Selected Entries From The Encyclopedia Of Sustainability Science And Technology (Encyclopedia Of Sustainability Science And Technology Ser.)
by Nicholas TsoulfanidisThis book provides an authoritative reference on all aspects of the nuclear energy enterprise for both fission and fusion reactors. Featuring 22 peer-reviewed chapters by recognized authorities in the field, the book offers concise yet comprehensive coverage of fundamentals, current areas of research, and goals for the future. Topics range from fundamental reactor physics calculations, reactor design, nuclear fuel resources, and the nuclear fuel cycle, to radiation detection and protection and the economics of nuclear power. All chapters have been updated from the first edition, with new chapters added on small modular reactors, medical applications - atomic and nuclear, and applications of radioisotopes. As each chapter is written by an acknowledged expert in the area, the reader can be assured that the text is accurate, up-to-date, and will appeal to a broad audience of undergraduate and graduate students, researchers, and energy industry experts.
Nuclear Engineering Fundamentals: A Practical Perspective
by Robert E. MastersonNUCLEAR ENGINEERING FUNDAMENTALS is the most modern, up-to-date, and reader friendly nuclear engineering textbook on the market today. It provides a thoroughly modern alternative to classical nuclear engineering textbooks that have not been updated over the last 20 years. Printed in full color, it conveys a sense of awe and wonder to anyone interested in the field of nuclear energy. It discusses nuclear reactor design, nuclear fuel cycles, reactor thermal-hydraulics, reactor operation, reactor safety, radiation detection and protection, and the interaction of radiation with matter. It presents an in-depth introduction to the science of nuclear power, nuclear energy production, the nuclear chain reaction, nuclear cross sections, radioactivity, and radiation transport. All major types of reactors are introduced and discussed, and the role of internet tools in their analysis and design is explored. Reactor safety and reactor containment systems are explored as well. To convey the evolution of nuclear science and engineering, historical figures and their contributions to evolution of the nuclear power industry are explored. Numerous examples are provided throughout the text, and are brought to life through life-like portraits, photographs, and colorful illustrations. The text follows a well-structured pedagogical approach, and provides a wide range of student learning features not available in other textbooks including useful equations, numerous worked examples, and lists of key web resources. As a bonus, a complete Solutions Manual and .PDF slides of all figures are available to qualified instructors who adopt the text. More than any other fundamentals book in a generation, it is student-friendly, and truly impressive in its design and its scope. It can be used for a one semester, a two semester, or a three semester course in the fundamentals of nuclear power. It can also serve as a great reference book for practicing nuclear scientists and engineers. To date, it has achieved the highest overall satisfaction of any mainstream nuclear engineering textbook available on the market today.
Nuclear Engineering Handbook (Mechanical and Aerospace Engineering Series)
by Kenneth D. KokBuilding upon the success of the first edition, the Nuclear Engineering Handbook, Second Edition, provides a comprehensive, up-to-date overview of nuclear power engineering. Consisting of chapters written by leading experts, this volume spans a wide range of topics in the areas of nuclear power reactor design and operation, nuclear fuel cycles, and radiation detection. Plant safety issues are addressed, and the economics of nuclear power generation in the 21st century are presented. The Second Edition also includes full coverage of Generation IV reactor designs, and new information on MRS technologies, small modular reactors, and fast reactors.
Nuclear Fission: Theories, Experiments and Applications
by Patrick Talou Ramona VogtThis book provides advanced students and postdocs, as well as current practitioners of any field of nuclear physics involving fission an understanding of the nuclear fission process. Key topics covered are: fission cross sections, fission fragment yields, neutron and gamma emission from fission and key nuclear technologies and applications where fission plays an important role. It addresses both fundamental aspects of the fission process and fission-based technologies including combining quantitative and microscopic modeling.
Nuclear Forces: The Making of the Physicist Hans Bethe
by Silvan S. SchweberOn the fiftieth anniversary of Hiroshima, Nobel-winning physicist Hans Bethe called on his fellow scientists to stop working on weapons of mass destruction. What drove Bethe, the head of Theoretical Physics at Los Alamos during the Manhattan Project, to renounce the weaponry he had once worked so tirelessly to create? That is one of the questions answered by Nuclear Forces, a riveting biography of Bethe’s early life and development as both a scientist and a man of principle. As Silvan Schweber follows Bethe from his childhood in Germany, to laboratories in Italy and England, and on to Cornell University, he shows how these differing environments were reflected in the kind of physics Bethe produced. Many of the young quantum physicists in the 1930s, including Bethe, had Jewish roots, and Schweber considers how Liberal Judaism in Germany helps explain their remarkable contributions. A portrait emerges of a man whose strategy for staying on top of a deeply hierarchical field was to tackle only those problems he knew he could solve. Bethe’s emotional maturation was shaped by his father and by two women of Jewish background: his overly possessive mother and his wife, who would later serve as an ethical touchstone during the turbulent years he spent designing nuclear bombs. Situating Bethe in the context of the various communities where he worked, Schweber provides a full picture of prewar developments in physics that changed the modern world, and of a scientist shaped by the unprecedented moral dilemmas those developments in turn created.
Nuclear Forces: The Making of the Physicist Hans Bethe
by Silvan S. Schweber“A highly readable account . . . tracing the future Nobel laureate through his formative years and up to the eve of World War II” (The Wall Street Journal).On the fiftieth anniversary of Hiroshima, Nobel-winning physicist Hans Bethe called on his fellow scientists to stop working on weapons of mass destruction. What drove Bethe, the head of Theoretical Physics at Los Alamos during the Manhattan Project, to renounce the weaponry he had once worked so tirelessly to create? That is one of the questions answered by Nuclear Forces, a riveting biography of Bethe’s early life and development as both a scientist and a man of principle.As Silvan Schweber follows Bethe from his childhood in Germany, to laboratories in Italy and England, and on to Cornell University, he shows how these differing environments were reflected in the kind of physics Bethe produced. Many of the young quantum physicists in the 1930s, including Bethe, had Jewish roots, and Schweber considers how Liberal Judaism in Germany helps explain their remarkable contributions. A portrait emerges of a man whose strategy for staying on top of a deeply hierarchical field was to tackle only those problems he knew he could solve.Bethe’s emotional maturation was shaped by his father and by two women of Jewish background: his overly possessive mother and his wife, who would later serve as an ethical touchstone during the turbulent years he spent designing nuclear bombs. Situating Bethe in the context of the various communities where he worked, Schweber provides a full picture of prewar developments in physics that changed the modern world, and of a scientist shaped by the unprecedented moral dilemmas those developments in turn created.Praise for Nuclear Forces“Schweber’s account of Hans Bethe’s life . . . reveals the origins of a charismatic scientist, grounded in the importance of his parents and his Jewish roots . . . [Schweber] recreates the social world that shaped the character of the last of the memorable young scientists who established the field of quantum mechanics.” —Publishers Weekly“Nuclear Forces is a carefully researched, historically and biographically insightful account of the development of a profession and of one of its leading representatives during a century in which physics and physicists played key roles in scientific, cultural, political, and military developments.” —David C. Cassidy, author of A Short History of Physics in the American Century
Nuclear Forensic Analysis
by Kenton J. Moody Patrick M. Grant Ian D. HutcheonNow in its second edition, Nuclear Forensic Analysis provides a multidisciplinary reference for forensic scientists, analytical and nuclear chemists, and nuclear physicists in one convenient source. The authors focus particularly on the chemical, physical, and nuclear aspects associated with the production or interrogation of a radioactive sample.
Nuclear Fuel Cycle
by B. S. Tomar P. R. Vasudeva Rao S. B. Roy Jose P. Panakkal Kanwar Raj A. N. NandakumarThe present book describes the various processes involved in different stages of the entire nuclear fuel cycle, which include exploration of uranium, thorium, and other nuclear materials, mining and milling of ores, conversion of the separated nuclear material into nuclear grade, fabrication of different types of nuclear fuels and their physical as well as chemical quality control, thermodynamics of the interaction among fuel and fission products during reactor operation, post irradiation examination, spent fuel reprocessing, radioactive waste management, accounting and control of nuclear materials, and safety aspects involved in handling and transportation of nuclear materials. The book provides the fundamental knowledge to the practicing nuclear scientists and engineers, young researchers, and postgraduate students interested in pursuing a career in nuclear industry in general and those engaged in human resource development in the field of nuclear science and technology in particular. It can also be prescribed as a textbook for a course on nuclear fuel cycle at postgraduate level.
Nuclear Functions in Plant Transcription, Signaling and Development
by Hailing Jin Olga PontesThe genome is more than a linear code as depicted by its DNA sequences as several interacting factors play a crucial role in shaping its organization and function. The complete sequences of a number of plant genomes and the recent advances of high-throughput technologies has fueled research efforts in the field of Plant Nuclear Biology unveiling numerous insights about the mechanisms underlying genome regulation. Genomic information is being integrated into molecular- and cellular-level mechanisms of the plant processes. A host of nuclear processes underlie key developmental processes as well as biotic and abiotic interactions. Non-coding RNAs have been increasingly recognized as players in gene expression and genome defense and integrity. However, in vivo, genomes exist as elaborate physical structures, and their functional properties are strongly determined by their cellular organization. Various types of subcellular structure have been identified in the nucleus, which are associated with transcription factors, RNA processing proteins and epigenetic regulators. Interestingly, these nuclear bodies display different behaviors in response to the environment. This book compiles a series of landmark discussions of the recent advances in plant nuclear biology research focusing in the functional relevance of the arrangement of genomes and nuclear processes that impact plant physiology and development.
Nuclear Fusion (Graduate Texts in Physics)
by Edward MorseThe pursuit of nuclear fusion as an energy source requires a broad knowledge of several disciplines. These include plasma physics, atomic physics, electromagnetics, materials science, computational modeling, superconducting magnet technology, accelerators, lasers, and health physics. Nuclear Fusion distills and combines these disparate subjects to create a concise and coherent foundation to both fusion science and technology. It examines all aspects of physics and technology underlying the major magnetic and inertial confinement approaches to developing nuclear fusion energy. It further chronicles latest developments in the field, and reflects the multi-faceted nature of fusion research, preparing advanced undergraduate and graduate students in physics and engineering to launch into successful and diverse fusion-related research.Nuclear Fusion reflects Dr. Morse’s research in both magnetic and inertial confinement fusion, working with the world’s top laboratories, and embodies his extensive thirty-five year career in teaching three courses in fusion plasma physics and fusion technology at University of California, Berkeley.