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Optimization Methods in Metabolic Networks
by Ali R. Zomorrodi Costas D. MaranasProvides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks Organizes, for the first time, the fundamentals of mathematical optimization in the context of metabolic network analysis Reviews the fundamentals of different classes of optimization problems including LP, MILP, MLP and MINLP Explains the most efficient ways of formulating a biological problem using mathematical optimization Reviews a variety of relevant problems in metabolic network curation, analysis and redesign with an emphasis on details of optimization formulations Provides a detailed treatment of bilevel optimization techniques for computational strain design and other relevant problems
Optimization Problems in Radiotherapy for Hypoxic Tumors (Biological and Medical Physics, Biomedical Engineering)
by Alexei V. ChvetsovThis book highlights the mathematical aspects of treatment outcomes analysis and dose optimization in radiotherapy for heterogeneous hypoxic tumors. Hypoxia is a major factor of cancer resistance to radiotherapy treatment and is present in most tumors encountered in humans. The author tried to present a systematic consideration of radiotherapy for hypoxic tumors, but the emphasis was put on mathematical content of the problems. The book contains new approaches to the concepts of tumor control probability, equivalent uniform dose and radiotherapy dose optimization for hypoxic tumors developed by the author. Significant attention in this book is paid to comparison of models with measured and clinical data; therefore, the reduction of model parameters to overcome overfitting (model parsimony) was followed as much as possible.
Optimization Techniques for Sustainable Environment Under Uncertainty (Engineering Optimization: Methods and Applications)
by Ritu Arora Shalini AroraThe book's objective is to develop mathematical structures that can be applied to real-life problems with sustainable goals. It focuses on the impact of sustainable living on social, economic, and environmental aspects, aiming to create optimization techniques that minimize emissions and maximize green energy. These optimization problems may include sustainable transport, cities, economic development, living, and tourism. The book brings together researchers, academics, and professionals from various fields to find optimal or satisfactory solutions for various environmentally friendly sustainable problems. It aims to achieve this not only with existing optimization techniques, but also with novel approaches such as lexicographic optimization, heuristic approaches, DEA, and genetic algorithms. The goal is to develop practical algorithms and methods applicable to these problems under uncertain circumstances and explore the potential for improving the efficiency of existing algorithms.
Optimization and Applicability of Bioprocesses
by Vipin Chandra Kalia Hemant J. Purohit Atul N. Vaidya Anshuman A. KhardenavisThis book argues that the sustainable management of resources requires a systematic approach that primarily involves the integration of green innovative biotechnological strategies and eco-engineering. It discusses how microbial community intelligence can be used for waste management and bio-remediation and explains how biological processes can be optimized by integrating genomics tools to provide perspectives on sustainable development. The book describes the application of modern molecular techniques such as fluorescence in situ hybridization (FISH), highly sensitive catalyzed reporter deposition (CARD)-FISH, in situ DNA-hybridization chain reaction (HCR) and methods for detecting mRNA and/or functional genes to optimize bioprocessess. These techniques, supplemented with metagenomic analysis, reveal that a large proportion of micro-organisms still remain to be identified and also that they play a vital role in establishing bioprocesses.
Optimization and Control Methods in Industrial Engineering and Construction
by Xiangyu Wang Honglei XuThis book presents recent advances in optimization and control methods with applications to industrial engineering and construction management. It consists of 15 chapters authored by recognized experts in a variety of fields including control and operation research, industrial engineering and project management. Topics include numerical methods in unconstrained optimization, robust optimal control problems, set splitting problems, optimum confidence interval analysis, a monitoring networks optimization survey, distributed fault detection, nonferrous industrial optimization approaches, neural networks in traffic flows, economic scheduling of CCHP systems, a project scheduling optimization survey, lean and agile construction project management, practical construction projects in Hong Kong, dynamic project management, production control in PC4P and target contracts optimization. The book offers a valuable reference work for scientists, engineers, researchers and practitioners in industrial engineering and construction management.
Optimization and Control of Bilinear Systems
by Panos M. Pardalos Vitaliy A. YatsenkoCovers developments in bilinear systems theory Focuses on the control of open physical processes functioning in a non-equilibrium mode Emphasis is on three primary disciplines: modern differential geometry, control of dynamical systems, and optimization theory Includes applications to the fields of quantum and molecular computing, control of physical processes, biophysics, superconducting magnetism, and physical information science
Optimization and Optimal Control in Automotive Systems
by Luigi Del Re Harald Waschl Ilya Kolmanovsky Maarten SteinbuchThis book demonstrates the use of the optimization techniques that are becoming essential to meet the increasing stringency and variety of requirements for automotive systems. It shows the reader how to move away from earlier approaches, based on some degree of heuristics, to the use of more and more common systematic methods. Even systematic methods can be developed and applied in a large number of forms so the text collects contributions from across the theory, methods and real-world automotive applications of optimization. Greater fuel economy, significant reductions in permissible emissions, new drivability requirements and the generally increasing complexity of automotive systems are among the criteria that the contributing authors set themselves to meet. In many cases multiple and often conflicting requirements give rise to multi-objective constrained optimization problems which are also considered. Some of these problems fall into the domain of the traditional multi-disciplinary optimization applied to system, sub-system or component design parameters and is performed based on system models; others require applications of optimization directly to experimental systems to determine either optimal calibration or the optimal control trajectory/control law. Optimization and Optimal Control in Automotive Systems reflects the state-of-the-art in and promotes a comprehensive approach to optimization in automotive systems by addressing its different facets, by discussing basic methods and showing practical approaches and specific applications of optimization to design and control problems for automotive systems. The book will be of interest both to academic researchers, either studying optimization or who have links with the automotive industry and to industrially-based engineers and automotive designers.
Optimization for Chemical and Biochemical Engineering: Theory, Algorithms, Modeling and Applications (Cambridge Series in Chemical Engineering)
by Ye Yuan Vassilios S. Vassiliadis Ehecatl Antonio del Rio Chanona Walter KähmDiscover the subject of optimization in a new light with this modern and unique treatment. Includes a thorough exposition of applications and algorithms in sufficient detail for practical use, while providing you with all the necessary background in a self-contained manner. Features a deeper consideration of optimal control, global optimization, optimization under uncertainty, multiobjective optimization, mixed-integer programming and model predictive control. Presents a complete coverage of formulations and instances in modelling where optimization can be applied for quantitative decision-making. As a thorough grounding to the subject, covering everything from basic to advanced concepts and addressing real-life problems faced by modern industry, this is a perfect tool for advanced undergraduate and graduate courses in chemical and biochemical engineering.
Optimization for Energy Systems and Supply Chains: Fundamentals and Applications (Green Chemistry and Chemical Engineering)
by Santanu Bandyopadhyay Viknesh Andiappan Denny K. S. NgTo curb the impacts of rising CO2 emissions, the Intergovernmental Panel on Climate Change report states that a net zero target needs to be achieved by the year 2055. Experts argue that this is a critical time to make important and accurate decisions. Thus, it is essential to have the right tools to efficiently plan and deploy future energy systems and supply chains. Mathematical models can provide decision-makers with the tools required to make well-informed decisions relating to development of energy systems and supply chains. This book provides an understanding of the various available energy systems, the basics behind mathematical models, the steps required to develop mathematical models, and examples/case studies where such models are applied. Divided into two parts, one covering basics for beginners and the other featuring contributed chapters offering illustrative examples, this book: Shows how mathematical models are applied to solve problems in energy systems and supply chains Provides fundamentals of the working principles of various energy systems and their technologies Offers basics of how to formulate and best practices for developing mathematical models, topics not covered in other titles Features a wide range of case studies Teaches readers to develop their own mathematical models to make decisions on energy systems This book is aimed at chemical, process, mechanical, and energy engineers.
Optimization for Thermal Design of Shell and Tube Heat Exchangers
by Mehdi HanifzadehA comprehensive guide to ensuring efficient, accurate, and cost-effective design of shell and tube heat exchangers across a variety of industries Effective thermal design of shell and tube heat exchangers is essential for maintaining performance and reducing costs in industries such as oil, gas, petrochemicals, and energy. In a field where heat exchangers are a significant investment, understanding how to design them efficiently is vital. Optimization for Thermal Design of Shell and Tube Heat Exchangers presents a clear, practical approach to achieving optimal results with minimal trials. Incorporating real-world examples and fast-track methodologies, this authoritative guide provides valuable tools to improve efficiency and manage data effectively while running design programs. Mehdi Hanifzadeh, a seasoned process principal engineer with more than 38 years of experience, offers proven strategies to reduce construction and maintenance costs while maintaining high design standards. Providing step-by-step guidance to designing these essential components with accuracy and speed, this book: Designed in oil refineries, gas processing, petrochemicals and power plants.Helps readers reduce construction costs while complying with industry design standardsFocuses on practical design methods and data management for cost-effective, high-quality outcomes.Provides clear and transparent design and calculation methods illustrated through numerous real-world examples and case studiesServes as a valuable educational and training resource for readers This title is an invaluable resource for new designers and experienced professionals specializing in the design and optimization of heat exchangers, and an ideal textbook for advanced chemical and mechanical engineering students taking courses in process design, energy systems, and industrial equipment.
Optimization in Food Engineering (Contemporary Food Engineering)
by Ferruh ErdoǧduWhile mathematically sophisticated methods can be used to better understand and improve processes, the nonlinear nature of food processing models can make their dynamic optimization a daunting task. With contributions from a virtual who's who in the food processing industry, Optimization in Food Engineering evaluates the potential uses and limitati
Optimization in Green Sustainability and Ecological Transition: ODS, Ischia, Italy, September 4–7, 2023 (AIRO Springer Series #12)
by Paola Festa Maurizio Bruglieri Giusy Macrina Ornella PisacaneThis book collects selected contributions of the “Optimization and Decision Science - ODS2023” international conference on the theme of optimization in green sustainability and ecological transition. ODS2023 was held in Ischia, 4–7 September 2023, and was organized by AIRO, the Italian Operations Research Society. The book offers new and original contributions on operations research, optimization, decision science, and prescriptive analytics from both a methodological and applied perspectives with a special focus on SDG related topics.It provides a state-of-the art on problem models and solving methods to address a widely class of real-world problems, arising in different application areas such as logistics, transportation, manufacturing, health, ICT and mobile networks, and emergency/disaster management. In addition, the scientific works collected in this book aim at providing significant contributions in the themes of sustainability, traffic and pollution reductions, and energy management.This book is aimed primarily at researchers and Ph.D. students in the Operations Research community. However, due to its interdisciplinary contents, this book is of high interest also for students and researchers from other disciplines, including artificial intelligence, computer sciences, finance, mathematics, and engineering as well as for practitioners facing complex decision-making problems in logistics, manufacturing production, and services.
Optimization in HPLC: Concepts and Strategies
by Stavros KromidasLearn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems.
Optimization in Industry: Present Practices And Future Scopes (Management And Industrial Engineering Ser.)
by J. Paulo Davim Shubhabrata DattaThis book describes different approaches for solving industrial problems like product design, process optimization, quality enhancement, productivity improvement and cost minimization. Several optimization techniques are described. The book covers case studies on the applications of classical as well as evolutionary and swarm optimization tools for solving industrial issues. The content is very helpful for industry personnel, particularly engineers from the Operation, R&D and Quality Assurance sectors, and also the academic researchers of different engineering and/or business administration background.
Optimization in Medicine and Biology (Engineering and Management Innovation)
by Gino J. Lim and Eva K. LeeThanks to recent advancements, optimization is now recognized as a crucial component in research and decision-making across a number of fields. Through optimization, scientists have made tremendous advances in cancer treatment planning, disease control, and drug development, as well as in sequencing DNA, and identifying protein structures.Op
Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: Advanced Topics (Statistics for Social and Behavioral Sciences)
by Linda M. Collins Kari C. KuglerBehavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This book provides additional information on a principled empirical framework for developing interventions that are more effective, efficient, economical, and scalable. This framework is introduced in the monograph, "Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy (MOST)" by Linda M. Collins (Springer, 2018). The present book is focused on advanced topics related to MOST. The chapters, all written by experts, are devoted to topics ranging from experimental design and data analysis to development of a conceptual model and implementation of a complex experiment in the field. Intervention scientists who are preparing to apply MOST will find this book an important reference and guide for their research. Fields to which this work pertains include public health (medicine, nursing, health economics, implementation sciences), behavioral sciences (psychology, criminal justice), statistics, and education.
Optimization of Chemical Processes: A Sustainable Perspective
by José María Ponce-Ortega Rogelio Ochoa-Barragán César Ramírez-MárquezThis textbook introduces readers to a comprehensive framework for the application of deterministic optimization strategies in the field of chemical processes, with a strong emphasis on sustainability.The book establishes a vital connection between fundamental deterministic optimization principles, optimization tools, and real-world application instances, all within the context of environmentally responsible practices. The approach put forth in this book is exceptionally versatile, allowing for the use of many optimization software and deterministic techniques.Contained in the book are many fundamental optimization concepts, encompassing linear programming, nonlinear programming, integer programming, and multi-objective optimization, all tailored to promote sustainable decision-making. Furthermore, the book provides practical examples illustrating the application of these techniques within sustainable chemical processes as tutorials.The textbook also explores the utilization of popular optimization software platforms such as GAMS, MATLAB, and Python, demonstrating how these tools can be leveraged for eco-friendly process optimization. Through this comprehensive framework, readers can not only acquire the skills needed to optimize a wide range of processes but also learn how to do so with sustainability at the forefront of their considerations. This approach streamlines the optimization process, eliminating unnecessary complications along the way and ensuring that environmental and ethical considerations are integral to the decision-making process.
Optimization of Dynamical Systems with Impulse Controls and Shocks (Systems & Control: Foundations & Applications)
by Boris Miller Evgeny RubinovichThis text explores the state-of-the-art in the rapidly developing theory of impulse control and introduces the theory of singular space-time transformations, a new method for studying shock mechanical systems. Two approaches in the theory of impulse control are presented: The first, more traditional approach defines the impulsive action as a discontinuity of phase coordinates depending on the current time, the state preceding the action, and its magnitude. The second requires the use of modern methods for describing dynamical systems - differential equations with measures. The impulse is treated as an idealization of a very short action of high magnitude, which produces an almost abrupt change of phase coordinates. The relation between these two approaches is also discussed, and several applications, both traditional and emerging, are considered. This text is intended for graduate students and researchers in control engineering and optimal control theory for dynamical systems. Readers are assumed to be familiar with the theory of ODEs, optimal control, and functional analysis, though an appendix is included that covers many of the necessary mathematical concepts.
Optimization of Energy Supply Systems: Modelling, Programming and Analysis (Lecture Notes in Energy #69)
by Janet NagelThis book describes how a model for optimizing the energy supply system in Germany can be implemented. It focuses on the open energy modeling framework (Oemof) program for modeling energy supply systems. The individual elements of Oemof are described, as well as the model’s structure. The technical components of Oemof are subsequently demonstrated in mathematical calculations, along with sufficient Python code to begin basic modeling. The book will appeal to anyone with an interest in optimization models for energy supply systems, or in the mathematical description of the technical components of such systems in practical implementation, using a real example, Oemof. Thermodynamic descriptions of combustion are provided, so that readers can focus on modeling aspects. Researchers and practitioners will also find the book useful, as it expands on their knowledge of the technical components of energy supply systems, supported with detailed mathematical calculations.
Optimization of Hydraulic Fracture Stages and Sequencing in Unconventional Formations
by Ahmed Alzahabi Mohamed Y. SolimanShale gas and/or oil play identification is subject to many screening processes for characteristics such as porosity, permeability, and brittleness. Evaluating shale gas and/or oil reservoirs and identifying potential sweet spots (portions of the reservoir rock that have high-quality kerogen content and brittle rock) requires taking into consideration multiple rock, reservoir, and geological parameters that govern production. The early determination of sweet spots for well site selection and fracturing in shale reservoirs is a challenge for many operators. With this limitation in mind, Optimization of Hydraulic Fracture Stages and Sequencing in Unconventional Formations develops an approach to improve the industry’s ability to evaluate shale gas and oil plays and is structured to lead the reader from general shale oil and gas characteristics to detailed sweet-spot classifications. The approach uses a new candidate selection and evaluation algorithm and screening criteria based on key geomechanical, petrophysical, and geochemical parameters and indices to obtain results consistent with existing shale plays and gain insights on the best development strategies going forward. The work introduces new criteria that accurately guide the development process in unconventional reservoirs in addition to reducing uncertainty and cost.
Optimization of Micro Processes in Fine Particle Agglomeration by Pelleting Flocculation
by Benjamin OyegbileEfficient particle separation in order to meet stringent regulatory standards represent one of the biggest challenges facing the process industry operators today. Emerging environmental problems such as climate change, population growth and natural resource depletion make it more compelling to undertake research into alternative phase separation techniques and optimization of existing ones. Meeting this challenge requires innovative, revolutionary and integrated approach in the design and optimization of various unit processes in fine particle separation. Flocculation is widely used as an effective phase separation technique across many process industries such as water and wastewater treatment and in minerals processing. In this work, a new pre-treatment technique was developed using a patented bench scale reactor unit as a technical proof of concept. Furthermore, the book provides a valuable insight into the hydrodynamics and fluid-particle interactions within the agglomeration units. The relatively high solids content of the stable pellets (approximately 30 %) and very low residual turbidity of the post-sedimentation supernatant (7 NTU) clearly demonstrate the potential of this technique. In addition to significantly improving the subsequent solid-liquid separation efficiency, this study also showed that the effluent can be recycled back into the sewer network or utilized for non-portable reuse. The findings obtained from this research will be extremely useful in the scaling up and optimization of the reactor system.
Optimization of Photovoltaic Power Systems
by Djamila Rekioua Ernest MatagnePhotovoltaic generation is one of the cleanest forms of energy conversion available. One of the advantages offered by solar energy is its potential to provide sustainable electricity in areas not served by the conventional power grid. Optimisation of Photovoltaic Power Systems details explicit modelling, control and optimisation of the most popular stand-alone applications such as pumping, power supply, and desalination. Each section is concluded by an example using the MATLAB® and Simulink® packages to help the reader understand and evaluate the performance of different photovoltaic systems. Optimisation of Photovoltaic Power Systems provides engineers, graduate and postgraduate students with the means to understand, assess and develop their own photovoltaic systems. As such, it is an essential tool for all those wishing to specialise in stand-alone photovoltaic systems. Optimisation of Photovoltaic Power Systems aims to enable all researchers in the field of electrical engineering to thoroughly understand the concepts of photovoltaic systems; find solutions to their problems; and choose the appropriate mathematical model for optimising photovoltaic energy.
Optimization of Process Flowsheets through Metaheuristic Techniques
by José María Ponce-Ortega Luis Germán Hernández-PérezThis textbook presents a general multi-objective optimization framework for optimizing chemical processes by implementing a link between process simulators and metaheuristic techniques. The proposed approach is general and shows how to implement links between different process simulators such as Aspen Plus®, HYSIS®, Super Pro Designer® linked to a variety of metaheuristic techniques implemented in Matlab®, Excel®, C++, and others, eliminating the numerical complications through the optimization process. Furthermore, the proposed framework allows the use of thermodynamic, design and constitutive equations implemented in the process simulator to implement any process. Aimed at graduate and undergraduate students, it presents introductory chapters for process simulators and metaheuristic optimization techniques and provides several worked exercises as well as proposed exercises. In addition, accompanying tutorial videos clearly explaining the implemented methodologies are available online. Also, some Matlab® routines are included as electronic supporting material.
Optimization of Solid-Phase Combinatorial Synthesis
by Bing Yan Anthony W. Czarnik"Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies."
Optimization of the Characterization of the Thermal Properties of the Building Envelope: Analysis of the Characterization of the Façades using Artificial Intelligence (SpringerBriefs in Applied Sciences and Technology)
by Carlos Rubio-Bellido David Bienvenido-HuertasThis book is about the optimization of the characterization of the thermal properties of building envelopes, through experimental tests and the use of artificial intelligence. It analyses periodic and stationary thermal properties using measurement approaches based on the heat flow meter method and the thermometric method. These measurements are then analysed using advanced artificial intelligence algorithms.The book is structured in four parts, beginning with a discussion of the importance of thermal properties in the energy performance of buildings. Secondly, theoretical and experimental methods for characterizing thermal properties are analysed. Then, the methodology is developed, and the characteristics and properties of the algorithms used are explored. Finally, the results obtained with the algorithms are analysed and the most appropriate approaches are determined.This book is of interest to researchers, civil and industrial engineers, energy auditors and architects, by providing a resource which improves energy audit tasks in existing buildings.