- Table View
- List View
Point-of-Care Diagnostics on a Chip
by David Issadore Robert M. WesterveltThe topic of this book is the development of automated and inexpensive tools that transfer medical tests from a specialized clinical laboratory directly to the point of care, using biochip technology. Immediate access to medically relevant biochemical information for doctors and nurses promises to revolutionize patient care and dramatically lower costs. The miniaturization and automation of medical tests are made possible by biochip technology, that integrates advances in integrated circuits, microelectromechanical systems (MEMS), microfluidics, and electronics. The target audience for this book includes engineering and biomedical researchers who would like to develop or apply biochip technology. They can use this book as a review of the field and as a guide for the development of novel biochip technology for point of care medicine. This book can also be used as a teaching tool for engineering and biomedical students, as well as a reference for physicians and health professionals.
Point-of-Care Solution for Osteoporosis Management: Design, Fabrication, and Validation of New Technology
by Patricia KhashayarThis book addresses the important clinical problem of accurately diagnosing osteoporosis, and analyzes how Bone Turnover Markers (BTMs) can improve osteoporosis detection. In her research, the author integrated microfluidic technology with electrochemical sensing to embody a reaction/detection chamber to measure serum levels of different biomarkers, creating a microfluidic proteomic platform that can easily be translated into a biomarker diagnostic. The Osteokit System, a result of the integration of electrochemical system and microfluidic chips, is a unique design that offers the potential for greater sensitivity. The implementation, feasibility, and specificity of the Osteokit platform is demonstrated in this book, which is appropriate for researchers working on bone biology and mechanics, as well as clinicians.
Point-of-Care Testing of COVID-19: Current Status, Clinical Impact, and Future Therapeutic Perspectives (SpringerBriefs in Applied Sciences and Technology)
by Abilash Gangula Brandon Kim Benjamin Casey Allison Hamill Hariharan Regunath Anandhi UpendranThis book highlights the role of point-of-care (POC) testing in the effective management of the coronavirus disease 2019 (COVID-19) pandemic with an in-depth focus on the recent developments in the field, existing gaps, and future directions. POC tests are of utmost importance as they facilitate rapid and decentralized testing without much instrumentation and technical expertise. The book describes the current status of POC COVID-19 testing in three broad categories: Molecular, antigen, and antibody. The advantages, limitations, and adaption of each of the POC tests are reviewed while highlighting their clinical impact in real-world settings. The role of POC testing for COVID-19 screening, diagnosis, and surveillance has been emphasized. The subtle difference between POC and at-home tests is discussed while elaborating on the necessity for the latter for enhancing clinical impacts. A spotlight on the influence of variants on the performance of POC-COVID-19 tests is provided. The consideration of clinical implications of POC testing in hospitals with regards to improving therapeutic options, patient flow, enhancing the infection control measures, and early recruitment of patients into clinical trials is explained. Finally, the future perspectives that will aid the research community in the development of POC tests for COVID-19 or any infectious disease, in general, are presented. Overall, we believe this book can benefit the research community as it (i) presents a comprehensive understanding of current COVID-19 POC testing methods (ii) highlights features required to transform the current tests developed during the past year as POC diagnostics, and (iii) provides insights to address the unmet challenges in the field.
Point-of-Care Ultrasound for the Neonatal and Pediatric Intensivist: A Practical Guide on the Use of POCUS
by Yogen Singh Cécile Tissot María Victoria Fraga Thomas ConlonThis book, written by internationally renowned experts, is a comprehensive text covering all aspects and recommendations regarding the use of POCUS for critically ill neonates and children. Point of Care Ultrasound (POCUS) for the Neonatal and Pediatric Intensivist is structured to address and expand upon recently published international evidence-based POCUS guidelines endorsed by the European Society of Paediatric and Neonatal Intensive Care (ESPNIC). The book is richly illustrated and includes a robust collection of individual POCUS images and cases. The Electronic Supplementary Materials offer high quality and interesting video clips complementing reader learning, particularly for neonatology, pediatric critical care, and general pediatric providers. Chapter authors provide a practical, experience-based approach to clinical integration of POCUS applications and highlight relevant supportive literature as well as important limitations to POCUS use in the management of critically ill children. The information within the book is also intended to support further clinical and educational research in the practice of pediatric POCUS.
Pointless: The Reality behind Quantum Theory
by RW BoyerThis book examines how major interpretations of quantum theory are progressing toward a more unified understanding and experience of nature. It offers subtle insights to address core issues of wave-particle duality, the measurement problem, the mind/body problem, determinism/indeterminism/free will, and the nature of consciousness. It draws from physics, consciousness studies, and ‘ancient Vedic science’ to outline a new holistic interpretation of quantum theory. Accessible and thought-provoking, it will be profoundly integrating for scholars and researchers in science and technology, in philosophy, and also in South Asian studies.
Points, Lines, and Surfaces at Criticality (Springer Theses)
by Edoardo LauriaThis thesis offers a fascinating journey through various non-perturbative aspects of Conformal Theories, in particular focusing on the Conformal Bootstrap Programme and its extensions to theories with various degrees of symmetry. Because of the preeminent role of Conformal Theories in Nature, as well as the great generality of the results here obtained, this analysis directly applies to many different areas of research. The content of this thesis is certainly relevant for the physics community as a whole and this relevance is well motivated and discussed along the various chapters of this work.The work is self-contained and starts with an original introduction to conformal theories, defects in such theories and how they lead to constraints on data and an extension of the bootstrap programme. This situation is often realized by critical systems with impurities, topological insulators, or – in the high-energy context – by Wilson and 't Hooft operators. The thesis continues with original research results of the author, including supersymmetric extensions. These results may be relevant non only in the high energy physics context - where supersymmetry is required for the theory to be consistent - but also for condensed matter systems that enjoy supersymmetry emergence at long distances.
Poison Arrows: North American Indian Hunting and Warfare
by David E. JonesA comprehensive survey of organic compounds used as poisons—on arrows and spears, in food, and even as insecticides—by numerous Native American tribes.Biological warfare is a menacing twenty-first-century issue, but its origins extend to antiquity. While the recorded use of toxins in warfare in some ancient populations is rarely disputed (the use of arsenical smoke in China, which dates to at least 1000 BC, for example) the use of &“poison arrows&” and other deadly substances by Native American groups has been fraught with contradiction. At last revealing clear documentation to support these theories, anthropologist David Jones transforms the realm of ethnobotany in Poison Arrows.Examining evidence within the few extant descriptive accounts of Native American warfare, along with grooved arrowheads and clues from botanical knowledge, Jones builds a solid case to indicate widespread and very effective use of many types of toxins. He argues that various groups applied them to not only warfare but also to hunting, and even as an early form of insect extermination. Culling extensive ethnological, historical, and archaeological data, Jones provides a thoroughly comprehensive survey of the use of ethnobotanical and entomological compounds applied in wide-ranging ways, including homicide and suicide. Although many narratives from the contact period in North America deny such uses, Jones now offers conclusive documentation to prove otherwise.A groundbreaking study of a subject that has been long overlooked, Poison Arrows imparts an extraordinary new perspective to the history of warfare, weaponry, and deadly human ingenuity.&“A unique contribution to the field of American Indian ethnology. . . . This information has never been compiled before, and I doubt that many ethnologists in the field have ever suspected the extent to which poison was used among North American Indians. This book significantly extends our understanding.&” —Wayne Van Horne, Associate Professor of Anthropology, Kennesaw State University
Poison and Poisoning: A Compendium of Cases, Catastrophes and Crimes
by Celia KellettThis fascinating book will be enjoyed both by those interested in the science of poisons and also by general readers who can dip in and find hair-raising horrors and calamities on every page.In this fascinating guide to poisons, Celia Kellett provides information and entertainment in equal measure as she explains clearly what all the different poisons are and how they work, giving us all the gory detail of how, by accident or design, they have led to the demise of so many people.From cyanide to the Black Widow spider, and from the Green Mamba snake to botulism, poisons can be found everywhere from the jungle to the refrigerator.Did you know, for example, that the Emperor Napoleon died from arsenic poisoning caused by the green dye used for the pattern on his wallpaper? Or that the Green Mamba’s venom is so toxic that a bite is fatal within half an hour? Or that 50,000 people die from snake bites every year in India?Poison is rarely out of the headlines, with recent stories including the murder, by polonium poisoning, of Alexander Litvinenko in London, allegedly by the KGB, The Horse Whisperer author Nicholas Evans becoming seriously ill in Scotland after eating poisonous mushrooms, and melamine poisoning in Chinese baby-milk formula.It is a subject that holds a fascination for the general public who (along with budding crime writers, and perhaps the KGB) will want to buy this excellent book in large numbers.
Poison and Poisoning: A Compendium of Cases, Catastrophes and Crimes
by Celia KellettThis fascinating book will be enjoyed both by those interested in the science of poisons and also by general readers who can dip in and find hair-raising horrors and calamities on every page.In this fascinating guide to poisons, Celia Kellett provides information and entertainment in equal measure as she explains clearly what all the different poisons are and how they work, giving us all the gory detail of how, by accident or design, they have led to the demise of so many people.From cyanide to the Black Widow spider, and from the Green Mamba snake to botulism, poisons can be found everywhere from the jungle to the refrigerator.Did you know, for example, that the Emperor Napoleon died from arsenic poisoning caused by the green dye used for the pattern on his wallpaper? Or that the Green Mamba’s venom is so toxic that a bite is fatal within half an hour? Or that 50,000 people die from snake bites every year in India?Poison is rarely out of the headlines, with recent stories including the murder, by polonium poisoning, of Alexander Litvinenko in London, allegedly by the KGB, The Horse Whisperer author Nicholas Evans becoming seriously ill in Scotland after eating poisonous mushrooms, and melamine poisoning in Chinese baby-milk formula.It is a subject that holds a fascination for the general public who (along with budding crime writers, and perhaps the KGB) will want to buy this excellent book in large numbers.
Poison or Medicine?
by Daniela WeilHave you ever wondered why most people can eat foods like chocolate, but dogs cannot? Or why you may get sick after drinking one too many sodas? Learn more about how some poisons are used for good. Some poisons can be used in medicines, but remember: too much of a good thing can be bad for you!
Poison: Deadly Deeds, Perilous Professions, and Murderous Medicines
by Sarah AlbeeScience geeks and armchair detectives will soak up this non-lethal, humorous account of the role poisons have played in human history. Perfect for STEM enthusiasts! For centuries, people have been poisoning one another—changing personal lives and the course of empires alike. From spurned spouses and rivals, to condemned prisoners like Socrates, to endangered emperors like Alexander the Great, to modern-day leaders like Joseph Stalin and Yasser Arafat, poison has played a starring role in the demise of countless individuals. And those are just the deliberate poisonings. Medical mishaps, greedy “snake oil” salesmen and food contaminants, poisonous Prohibition, and industrial toxins also impacted millions. Part history, part chemistry, part whodunit, Poison: Deadly Deeds, Perilous Professions, and Murderous Medicines traces the role poisons have played in history from antiquity to the present and shines a ghoulish light on the deadly intersection of human nature . . . and Mother Nature.
Poisoned Profits
by Philip Shabecoff Alice ShabecoffIn this shocking and sobering book, two fearless journalists directly and definitively link industrial toxins to the current rise in childhood disease and death. In the tradition of Silent Spring,Poisoned Profitsis a landmark investigation, an eye-opening account of a country that prizes money over children’s health. With indisputable data, Philip Shabecoff and Alice Shabecoff reveal that the children of baby boomers–the first to be raised in a truly “toxified” world–have higher rates of birth defects, asthma, cancer, autism, and other serious illnesses than previous generations. In piercing case histories, the authors identify the culprit as corporate pollution. Here are the stories of such places as Dickson, Tennessee, where babies were born with cleft lips and palates after landfill chemicals seeped into the water, and Port Neches, Texas, where so many graduates of a high school near synthetic rubber and chemical plants contracted cancer that the school was nicknamed “Leukemia High. ” The danger to our children isn’t just in the outside world, though. The Shabecoffs provide evidence that our homes are now infested with everything from dangerous flame retardants in crib mattresses to harmful plastic softeners in teething rings to antibiotics and arsenic in chicken–additives that are absorbed by growing and physically vulnerable kids as well as by pregnant women. Compounding the problem are chemical corporations that sabotage investigations and regulations, a government that refuses to police these companies, and corporate-hired scientists who keep pertinent secrets massaged with skewed data of their own. Poisoned Profitsalso demonstrates how people are fighting back, whether through grassroots parents’ groups putting pressure on politicians, the rise of “ecotheology” in the pulpits of formerly indifferent churches, or the new “green chemistry” being practiced in labs to replace bad elements with good. The Shabecoffs also include helpful tips on reducing risks to children in how they eat and play, and in how parents clean and maintain their homes. Powerful, unflinching, and eminently readable,Poisoned Profitsis a wake-up call that is bound to inspire talk and force change. From the Hardcover edition.
Poisoner in Chief: Sidney Gottlieb and the CIA Search for Mind Control
by Stephen KinzerThe bestselling author of All the Shah’s Men and The Brothers tells the astonishing story of the man who oversaw the CIA’s secret drug and mind-control experiments of the 1950s and ’60s.The visionary chemist Sidney Gottlieb was the CIA’s master magician and gentlehearted torturer—the agency’s “poisoner in chief.” As head of the MK-ULTRA mind control project, he directed brutal experiments at secret prisons on three continents. He made pills, powders, and potions that could kill or maim without a trace—including some intended for Fidel Castro and other foreign leaders. He paid prostitutes to lure clients to CIA-run bordellos, where they were secretly dosed with mind-altering drugs. His experiments spread LSD across the United States, making him a hidden godfather of the 1960s counterculture. For years he was the chief supplier of spy tools used by CIA officers around the world.Stephen Kinzer, author of groundbreaking books about U.S. clandestine operations, draws on new documentary research and original interviews to bring to life one of the most powerful unknown Americans of the twentieth century. Gottlieb’s reckless experiments on “expendable” human subjects destroyed many lives, yet he considered himself deeply spiritual. He lived in a remote cabin without running water, meditated, and rose before dawn to milk his goats.During his twenty-two years at the CIA, Gottlieb worked in the deepest secrecy. Only since his death has it become possible to piece together his astonishing career at the intersection of extreme science and covert action. Poisoner in Chief reveals him as a clandestine conjurer on an epic scale.
Poisonous Plants and Phytochemicals in Drug Discovery
by Chukwuebuka Egbuna Andrew G. Mtewa G.M. Narasimha RaoFocusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery - Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery - Written and edited by leading researchers in phytochemistry, medicinal chemistry, analytical chemistry, toxicology, and more - Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Poisonous Skies: Acid Rain and the Globalization of Pollution
by Rachel Emma RothschildThe climate change reckoning looms. As scientists try to discern what the Earth’s changing weather patterns mean for our future, Rachel Rothschild seeks to understand the current scientific and political debates surrounding the environment through the history of another global environmental threat: acid rain. The identification of acid rain in the 1960s changed scientific and popular understanding of fossil fuel pollution’s potential to cause regional—and even global—environmental harms. It showed scientists that the problem of fossil fuel pollution was one that crossed borders—it could travel across vast stretches of the earth’s atmosphere to impact ecosystems around the world. This unprecedented transnational reach prompted governments, for the first time, to confront the need to cooperate on pollution policies, transforming environmental science and diplomacy. Studies of acid rain and other pollutants brought about a reimagining of how to investigate the natural world as a complete entity, and the responses of policy makers, scientists, and the public set the stage for how societies have approached other prominent environmental dangers on a global scale, most notably climate change. Grounded in archival research spanning eight countries and five languages, as well as interviews with leading scientists from both government and industry, Poisonous Skies is the first book to examine the history of acid rain in an international context. By delving deep into our environmental past, Rothschild hopes to inform its future, showing us how much is at stake for the natural world as well as what we risk—and have already risked—by not acting.
Poisons: An Introduction for Forensic Investigators
by David J. GeorgeA unique book on recognition and investigation of criminal poisoning for investigators of all backgrounds and stages of their careers. Poisons: An Introduction for Forensic Investigators is a concise yet comprehensive overview of toxicants and unanticipated circumstances in which poisoning occurs. This book expands awareness of poisoning possibilities, heightens recognition of the toxic potential of many substances, and provides information to aid in focusing investigations. Poisons discusses life-threatening toxic substances and agents that modify behavior to achieve criminal goals. These include drugs that facilitate sexual assaults and robberies, and those found in medical child abuse and drug-product tampering. More than 230 case studies illustrate both unintentional and intentional poisoning and highlight situations where poisoning may not immediately be apparent. Information is included in pertinent criminal poisoning cases to illustrate the temperament of poisoners, their relationship to victims, their basis for poison selection, and their method of administration. Since Poisons is written by a single author, the discussions, format, educational level, and terminology remain consistent to aid crime scene investigators, homicide detectives, forensic scientists, death investigators, toxicologists, medical examiners, attorneys, and students. The book's more than 650 references are an asset to frame knowledge as well as a resource to return to again and again.
Poisson Theory of Elastic Plates (Springer Tracts in Mechanical Engineering)
by Kaza Vijayakumar Girish Kumar RamaiahThis groundbreaking book resolves the main lacuna in Kirchhoff theory of bending of plates in the Poisson-Kirchhoff boundary conditions paradox through the introduction of auxiliary problem governing transverse stresses. The book highlights new primary bending problem which is formulated and analyzed by the application of developed Poisson theory. Analysis with prescribed transverse stresses along faces of the plate, neglected in most reported theories, is presented with an additional term in displacements. The book presents a systematic procedure for the analysis of unsymmetrical laminates. This volume will be a useful reference for students, practicing engineers as well as researchers in applied mechanics.
Polar Auxin Transport
by František Baluška Rujin ChenThe importance of the plant growth regulator auxin for plant growth has long been recognized, even before the discovery of its chemical structures in the early 20th century. Physiological studies in the decades since have demonstrated that auxin is unidirectionally transported in plants, a process dubbed polar auxin transport. It is the polar auxin transport process that generates a local auxin concentration gradient and regulates a broad array of physiological and developmental processes. The discoveries of auxin transport carrier proteins that mediate auxin influx into and efflux out of transport-competent cells and auxin receptor proteins for auxin signaling in the last few decades represent significant milestones in auxin research and open up opportunities to probe the cellular and molecular processes that regulate auxin transport and integrate environmental cues with signaling processes. Remarkably, components of the polar auxin transport machinery are present in both lower plants such as mosses and higher plants including monocots and eudicots, illustrating the key role of polar auxin transport in plant evolution. This book highlights topics ranging from physiological and genetic studies of polar auxin transport in plant development, to growth responses to the environment and plant-microbe interactions, to hormonal cross-talks with various cellular and molecular regulatory processes essential for polar auxin transport.
Polar Bear
by Candace FlemingThis companion book to the authors&’ Sibert award-winning Honeybee explores the life and habitat of a majestic endangered species through dramatic text and sumptuous illustration.April in the Arctic . . .Cold winds send snow clouds scuttling across the sky.Temperatures barely nudge above freezing.But every now and again,The cloud cover parts,The sun shines down,And the frozen world stretches awake. As spring approaches in the Arctic, a mother polar bear and her two cubs tentatively emerge from hibernation to explore the changing landscape. When it is time, she takes her cubs on a forty-mile journey, back to their home on the ice. Along the way, she fends off wolves, hunts for food, and swims miles and miles. This companion book to Honeybee and Giant Squid features the unique talents of Fleming and Rohmann on a perennially popular subject. Eric Rohmann's magnificent oil paintings feature (as in Honeybee) a spectacular gatefold of the polar landscape.A Junior Library Guild Gold Standard Selection
Polar Bear, Why Is Your World Melting?
by Robert E WellsIn the Arctic, the summer ice is melting, making it hard for polar bears and their cubs to survive. Why is the world getting warmer? The heat of the sun is trapped by the "greenhouse" gases that surround Earth--carbon dioxide, methane, nitrous oxide, and water vapor. If there is just the right amount of these trapped gases, the air is warm enough for plants, animals, and people to thrive. But now there is too much greenhouse gas, especially carbon dioxide. Polar bears, and all of us, are in trouble. Robert E. Wells, who lives in Washington State, shows why so much carbon dioxide is going into the air and what we can do to help keep Earth cool.
Polar Bears (Readers)
by Laura MarshWith their beautiful white fur and powerful presence, polar bears rule the Arctic. These majestic giants swim from iceberg to iceberg in chilling waters, care for their adorable cubs, and are threatened by global warming. In this level 1 reader you'll learn all you ever wanted to know about polar bears and so much more. Complete with fascinating facts and beautiful images, National Geographic Readers: Polar Bears can't miss.
Polar Bears (Rigby PM Collection Ruby (Levels 27-28), Fountas & Pinnell Select Collections Grade 3 Level Q)
by Beverley RandellPolar Bears by Beverley Randell
Polar Bears' Search for Ice: A Cause and Effect Investigation (Animal's on the Edge)
by Gillia M. OlsonPolar bears are losing their Arctic homes. As the Arctic ice shrinks, so does their habitat. Polar bears have become animals on the edge. Discover how scientists are trying to answer the questions behind polar bears' search for ice.
Polar Bears: A Complete Guide to Their Biology and Behavior
by Andrew E. DerocherHonorable Mention, 2012 National Outdoor Book AwardsThe polar bear, king of the Arctic, is one of the world’s most recognizable animals. Images of the majestic beasts roaming across the ice cap, plunging into frigid waters, and playing with furry cubs have come to symbolize the beauty and grandeur of the Arctic. Andrew E. Derocher and Wayne Lynch have spent decades following the bears, and this book offers the most comprehensive and readable review of their biology, ecology, behavior, and conservation.With gripping photographs by Lynch, a preeminent wildlife photographer, and the personal stories of Derocher, this book is as stunning to look at as it is fascinating to read. It weaves together their remarkable experiences with the latest research to tell the amazing story of these Arctic predators, tracing the animals back to their evolutionary roots and looking ahead to the future of polar bears on a warming planet Earth.Through informative and engaging language, Derocher carefully explains the sea ice ecosystem that is essential to the survival of polar bears. He addresses the threat of global warming to the Arctic—home to polar bears for tens of thousands of years—and describes in impressive detail their feeding habits, distribution, den ecology, and reproduction. Lynch’s vivid photographs capture all this and more as they chronicle the wide range of polar bear behavior, from family rituals to ferocious predatory practices. Captivating, accurate, and inspiring, Polar Bears belongs in the hands of all who love the wild.
Polar Dielectrics and Their Applications
by Jack C. Burfoot George W. TaylorThis title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1979.